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Network neighborhood for query Sequence : ZAN_MOUSE

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ZAN_MOUSE
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ZAN_HUMAN
θ value	0 (rank : 1)	NC score	0.801019 (rank : 2)
Query Neighborhood Hits	808	Target Neighborhood Hits	679	Shared Neighborhood Hits	427
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	808	Target Neighborhood Hits	808	Shared Neighborhood Hits	808
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

TECTA_HUMAN
θ value	4.12933e-154 (rank : 3)	NC score	0.606324 (rank : 38)
Query Neighborhood Hits	808	Target Neighborhood Hits	239	Shared Neighborhood Hits	199
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	2.04937e-153 (rank : 4)	NC score	0.614464 (rank : 32)
Query Neighborhood Hits	808	Target Neighborhood Hits	244	Shared Neighborhood Hits	206
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

MUC5B_HUMAN
θ value	2.23575e-83 (rank : 5)	NC score	0.715387 (rank : 3)
Query Neighborhood Hits	808	Target Neighborhood Hits	1020	Shared Neighborhood Hits	415
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

VWF_MOUSE
θ value	1.65806e-78 (rank : 6)	NC score	0.630246 (rank : 24)
Query Neighborhood Hits	808	Target Neighborhood Hits	381	Shared Neighborhood Hits	277
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

SSPO_MOUSE
θ value	3.69378e-78 (rank : 7)	NC score	0.650209 (rank : 7)
Query Neighborhood Hits	808	Target Neighborhood Hits	800	Shared Neighborhood Hits	452
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

MUC2_HUMAN
θ value	7.45998e-71 (rank : 8)	NC score	0.617896 (rank : 28)
Query Neighborhood Hits	808	Target Neighborhood Hits	906	Shared Neighborhood Hits	303
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

VWF_HUMAN
θ value	2.17053e-70 (rank : 9)	NC score	0.649651 (rank : 8)
Query Neighborhood Hits	808	Target Neighborhood Hits	396	Shared Neighborhood Hits	280
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

BMPER_MOUSE
θ value	8.87376e-48 (rank : 10)	NC score	0.642600 (rank : 15)
Query Neighborhood Hits	808	Target Neighborhood Hits	194	Shared Neighborhood Hits	169
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BMPER_HUMAN
θ value	5.7518e-47 (rank : 11)	NC score	0.625438 (rank : 26)
Query Neighborhood Hits	808	Target Neighborhood Hits	175	Shared Neighborhood Hits	151
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

FBN1_MOUSE
θ value	4.41421e-39 (rank : 12)	NC score	0.647533 (rank : 13)
Query Neighborhood Hits	808	Target Neighborhood Hits	563	Shared Neighborhood Hits	407
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_HUMAN
θ value	1.08726e-37 (rank : 13)	NC score	0.648107 (rank : 11)
Query Neighborhood Hits	808	Target Neighborhood Hits	557	Shared Neighborhood Hits	406
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
θ value	5.39604e-37 (rank : 14)	NC score	0.650662 (rank : 5)
Query Neighborhood Hits	808	Target Neighborhood Hits	549	Shared Neighborhood Hits	420
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

NOTC1_HUMAN
θ value	1.24399e-33 (rank : 15)	NC score	0.613190 (rank : 33)
Query Neighborhood Hits	808	Target Neighborhood Hits	906	Shared Neighborhood Hits	420
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
θ value	1.24399e-33 (rank : 16)	NC score	0.604650 (rank : 39)
Query Neighborhood Hits	808	Target Neighborhood Hits	1069	Shared Neighborhood Hits	435
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

MEGF6_HUMAN
θ value	1.0531e-32 (rank : 17)	NC score	0.672076 (rank : 4)
Query Neighborhood Hits	808	Target Neighborhood Hits	671	Shared Neighborhood Hits	475
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

FRAS1_HUMAN
θ value	1.37539e-32 (rank : 18)	NC score	0.536119 (rank : 88)
Query Neighborhood Hits	808	Target Neighborhood Hits	759	Shared Neighborhood Hits	387
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FBN2_HUMAN
θ value	3.06405e-32 (rank : 19)	NC score	0.650606 (rank : 6)
Query Neighborhood Hits	808	Target Neighborhood Hits	560	Shared Neighborhood Hits	412
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

NOTC3_HUMAN
θ value	2.59387e-31 (rank : 20)	NC score	0.608812 (rank : 36)
Query Neighborhood Hits	808	Target Neighborhood Hits	1062	Shared Neighborhood Hits	465
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FRAS1_MOUSE
θ value	3.3877e-31 (rank : 21)	NC score	0.526664 (rank : 96)
Query Neighborhood Hits	808	Target Neighborhood Hits	747	Shared Neighborhood Hits	383
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NOTC3_MOUSE
θ value	3.3877e-31 (rank : 22)	NC score	0.608175 (rank : 37)
Query Neighborhood Hits	808	Target Neighborhood Hits	975	Shared Neighborhood Hits	454
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_MOUSE
θ value	5.77852e-31 (rank : 23)	NC score	0.629426 (rank : 25)
Query Neighborhood Hits	808	Target Neighborhood Hits	916	Shared Neighborhood Hits	435
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC4_MOUSE
θ value	5.97985e-28 (rank : 24)	NC score	0.588582 (rank : 51)
Query Neighborhood Hits	808	Target Neighborhood Hits	872	Shared Neighborhood Hits	432
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

FBN3_HUMAN
θ value	6.61148e-27 (rank : 25)	NC score	0.642197 (rank : 16)
Query Neighborhood Hits	808	Target Neighborhood Hits	543	Shared Neighborhood Hits	395
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

PCSK5_MOUSE
θ value	4.28545e-26 (rank : 26)	NC score	0.491622 (rank : 130)
Query Neighborhood Hits	808	Target Neighborhood Hits	613	Shared Neighborhood Hits	388
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

NOTC2_HUMAN
θ value	3.07116e-24 (rank : 27)	NC score	0.602169 (rank : 41)
Query Neighborhood Hits	808	Target Neighborhood Hits	1113	Shared Neighborhood Hits	460
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_HUMAN
θ value	3.39556e-23 (rank : 28)	NC score	0.592799 (rank : 44)
Query Neighborhood Hits	808	Target Neighborhood Hits	905	Shared Neighborhood Hits	435
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NELL1_HUMAN
θ value	4.15078e-21 (rank : 29)	NC score	0.649584 (rank : 10)
Query Neighborhood Hits	808	Target Neighborhood Hits	451	Shared Neighborhood Hits	359
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NACAM_MOUSE
θ value	1.74391e-19 (rank : 30)	NC score	0.177798 (rank : 401)
Query Neighborhood Hits	808	Target Neighborhood Hits	1866	Shared Neighborhood Hits	169
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CRIM1_HUMAN
θ value	1.13037e-18 (rank : 31)	NC score	0.618361 (rank : 27)
Query Neighborhood Hits	808	Target Neighborhood Hits	362	Shared Neighborhood Hits	291
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

JAG1_HUMAN
θ value	1.24977e-17 (rank : 32)	NC score	0.649632 (rank : 9)
Query Neighborhood Hits	808	Target Neighborhood Hits	514	Shared Neighborhood Hits	399
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

MUC1_HUMAN
θ value	1.058e-16 (rank : 33)	NC score	0.102989 (rank : 591)
Query Neighborhood Hits	808	Target Neighborhood Hits	975	Shared Neighborhood Hits	87
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

JAG1_MOUSE
θ value	1.38178e-16 (rank : 34)	NC score	0.647749 (rank : 12)
Query Neighborhood Hits	808	Target Neighborhood Hits	518	Shared Neighborhood Hits	396
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

NELL2_HUMAN
θ value	1.38178e-16 (rank : 35)	NC score	0.632859 (rank : 22)
Query Neighborhood Hits	808	Target Neighborhood Hits	449	Shared Neighborhood Hits	350
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

MAMC2_MOUSE
θ value	2.35696e-16 (rank : 36)	NC score	0.243618 (rank : 303)
Query Neighborhood Hits	808	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

JAG2_HUMAN
θ value	4.02038e-16 (rank : 37)	NC score	0.640119 (rank : 19)
Query Neighborhood Hits	808	Target Neighborhood Hits	491	Shared Neighborhood Hits	387
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

MAP4_HUMAN
θ value	6.85773e-16 (rank : 38)	NC score	0.192526 (rank : 365)
Query Neighborhood Hits	808	Target Neighborhood Hits	428	Shared Neighborhood Hits	67
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

LRP2_HUMAN
θ value	8.95645e-16 (rank : 39)	NC score	0.504359 (rank : 117)
Query Neighborhood Hits	808	Target Neighborhood Hits	573	Shared Neighborhood Hits	383
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

MAMC2_HUMAN
θ value	5.8054e-15 (rank : 40)	NC score	0.242016 (rank : 307)
Query Neighborhood Hits	808	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MDC1_HUMAN
θ value	5.8054e-15 (rank : 41)	NC score	0.175982 (rank : 404)
Query Neighborhood Hits	808	Target Neighborhood Hits	1446	Shared Neighborhood Hits	121
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

GP112_HUMAN
θ value	1.68911e-14 (rank : 42)	NC score	0.162805 (rank : 433)
Query Neighborhood Hits	808	Target Neighborhood Hits	441	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

LTBP2_HUMAN
θ value	2.20605e-14 (rank : 43)	NC score	0.617095 (rank : 29)
Query Neighborhood Hits	808	Target Neighborhood Hits	552	Shared Neighborhood Hits	380
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

SREC_HUMAN
θ value	2.20605e-14 (rank : 44)	NC score	0.644003 (rank : 14)
Query Neighborhood Hits	808	Target Neighborhood Hits	645	Shared Neighborhood Hits	432
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

JAG2_MOUSE
θ value	3.76295e-14 (rank : 45)	NC score	0.634097 (rank : 20)
Query Neighborhood Hits	808	Target Neighborhood Hits	504	Shared Neighborhood Hits	393
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LRP1B_HUMAN
θ value	1.09485e-13 (rank : 46)	NC score	0.533069 (rank : 92)
Query Neighborhood Hits	808	Target Neighborhood Hits	602	Shared Neighborhood Hits	396
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TENX_HUMAN
θ value	1.09485e-13 (rank : 47)	NC score	0.509747 (rank : 108)
Query Neighborhood Hits	808	Target Neighborhood Hits	789	Shared Neighborhood Hits	408
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LRP1_HUMAN
θ value	1.86753e-13 (rank : 48)	NC score	0.536179 (rank : 87)
Query Neighborhood Hits	808	Target Neighborhood Hits	617	Shared Neighborhood Hits	400
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP1B_MOUSE
θ value	4.16044e-13 (rank : 49)	NC score	0.529456 (rank : 95)
Query Neighborhood Hits	808	Target Neighborhood Hits	606	Shared Neighborhood Hits	397
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SCUB3_HUMAN
θ value	4.16044e-13 (rank : 50)	NC score	0.564398 (rank : 67)
Query Neighborhood Hits	808	Target Neighborhood Hits	428	Shared Neighborhood Hits	307
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

NELL2_MOUSE
θ value	7.09661e-13 (rank : 51)	NC score	0.632044 (rank : 23)
Query Neighborhood Hits	808	Target Neighborhood Hits	436	Shared Neighborhood Hits	347
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

TENA_HUMAN
θ value	7.09661e-13 (rank : 52)	NC score	0.521666 (rank : 98)
Query Neighborhood Hits	808	Target Neighborhood Hits	631	Shared Neighborhood Hits	384
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

LTBP4_MOUSE
θ value	1.58096e-12 (rank : 53)	NC score	0.615490 (rank : 30)
Query Neighborhood Hits	808	Target Neighborhood Hits	607	Shared Neighborhood Hits	365
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FBLN2_MOUSE
θ value	4.59992e-12 (rank : 54)	NC score	0.581448 (rank : 58)
Query Neighborhood Hits	808	Target Neighborhood Hits	505	Shared Neighborhood Hits	316
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

CSPG2_MOUSE
θ value	7.84624e-12 (rank : 55)	NC score	0.381045 (rank : 210)
Query Neighborhood Hits	808	Target Neighborhood Hits	711	Shared Neighborhood Hits	299
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

HMCN1_HUMAN
θ value	7.84624e-12 (rank : 56)	NC score	0.357843 (rank : 228)
Query Neighborhood Hits	808	Target Neighborhood Hits	983	Shared Neighborhood Hits	334
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

LTBP2_MOUSE
θ value	7.84624e-12 (rank : 57)	NC score	0.611060 (rank : 35)
Query Neighborhood Hits	808	Target Neighborhood Hits	617	Shared Neighborhood Hits	382
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

SREC2_MOUSE
θ value	1.02475e-11 (rank : 58)	NC score	0.614785 (rank : 31)
Query Neighborhood Hits	808	Target Neighborhood Hits	605	Shared Neighborhood Hits	403
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

KR104_HUMAN
θ value	1.74796e-11 (rank : 59)	NC score	0.640817 (rank : 18)
Query Neighborhood Hits	808	Target Neighborhood Hits	313	Shared Neighborhood Hits	257
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

LTBP3_HUMAN
θ value	1.74796e-11 (rank : 60)	NC score	0.589442 (rank : 49)
Query Neighborhood Hits	808	Target Neighborhood Hits	502	Shared Neighborhood Hits	358
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

KR107_HUMAN
θ value	2.28291e-11 (rank : 61)	NC score	0.640927 (rank : 17)
Query Neighborhood Hits	808	Target Neighborhood Hits	330	Shared Neighborhood Hits	275
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

SCUB3_MOUSE
θ value	5.08577e-11 (rank : 62)	NC score	0.566060 (rank : 66)
Query Neighborhood Hits	808	Target Neighborhood Hits	442	Shared Neighborhood Hits	313
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SREC2_HUMAN
θ value	8.67504e-11 (rank : 63)	NC score	0.612081 (rank : 34)
Query Neighborhood Hits	808	Target Neighborhood Hits	645	Shared Neighborhood Hits	401
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LTB1L_MOUSE
θ value	1.47974e-10 (rank : 64)	NC score	0.583000 (rank : 55)
Query Neighborhood Hits	808	Target Neighborhood Hits	514	Shared Neighborhood Hits	357
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	1.47974e-10 (rank : 65)	NC score	0.582352 (rank : 57)
Query Neighborhood Hits	808	Target Neighborhood Hits	479	Shared Neighborhood Hits	338
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SORL_MOUSE
θ value	1.47974e-10 (rank : 66)	NC score	0.380435 (rank : 212)
Query Neighborhood Hits	808	Target Neighborhood Hits	439	Shared Neighborhood Hits	252
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

FBLN2_HUMAN
θ value	1.9326e-10 (rank : 67)	NC score	0.576097 (rank : 61)
Query Neighborhood Hits	808	Target Neighborhood Hits	392	Shared Neighborhood Hits	282
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LAMA5_HUMAN
θ value	1.9326e-10 (rank : 68)	NC score	0.466835 (rank : 140)
Query Neighborhood Hits	808	Target Neighborhood Hits	976	Shared Neighborhood Hits	400
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MDGA1_HUMAN
θ value	4.30538e-10 (rank : 69)	NC score	0.113141 (rank : 551)
Query Neighborhood Hits	808	Target Neighborhood Hits	358	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

TENA_MOUSE
θ value	4.30538e-10 (rank : 70)	NC score	0.506495 (rank : 115)
Query Neighborhood Hits	808	Target Neighborhood Hits	596	Shared Neighborhood Hits	368
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

KR106_HUMAN
θ value	7.34386e-10 (rank : 71)	NC score	0.633140 (rank : 21)
Query Neighborhood Hits	808	Target Neighborhood Hits	347	Shared Neighborhood Hits	285
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

SORL_HUMAN
θ value	1.25267e-09 (rank : 72)	NC score	0.368834 (rank : 220)
Query Neighborhood Hits	808	Target Neighborhood Hits	440	Shared Neighborhood Hits	250
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

DLL1_MOUSE
θ value	2.13673e-09 (rank : 73)	NC score	0.602991 (rank : 40)
Query Neighborhood Hits	808	Target Neighborhood Hits	456	Shared Neighborhood Hits	373
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

GRN_MOUSE
θ value	2.13673e-09 (rank : 74)	NC score	0.535951 (rank : 89)
Query Neighborhood Hits	808	Target Neighborhood Hits	248	Shared Neighborhood Hits	221
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

LDLR_HUMAN
θ value	2.79066e-09 (rank : 75)	NC score	0.485515 (rank : 131)
Query Neighborhood Hits	808	Target Neighborhood Hits	375	Shared Neighborhood Hits	285
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

AGRIN_HUMAN
θ value	3.64472e-09 (rank : 76)	NC score	0.540253 (rank : 84)
Query Neighborhood Hits	808	Target Neighborhood Hits	582	Shared Neighborhood Hits	384
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

DLL4_MOUSE
θ value	4.76016e-09 (rank : 77)	NC score	0.592188 (rank : 45)
Query Neighborhood Hits	808	Target Neighborhood Hits	440	Shared Neighborhood Hits	360
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

GRN_HUMAN
θ value	4.76016e-09 (rank : 78)	NC score	0.543667 (rank : 81)
Query Neighborhood Hits	808	Target Neighborhood Hits	268	Shared Neighborhood Hits	226
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KR109_HUMAN
θ value	6.21693e-09 (rank : 79)	NC score	0.523210 (rank : 97)
Query Neighborhood Hits	808	Target Neighborhood Hits	226	Shared Neighborhood Hits	200
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10B_HUMAN
θ value	6.21693e-09 (rank : 80)	NC score	0.519144 (rank : 103)
Query Neighborhood Hits	808	Target Neighborhood Hits	269	Shared Neighborhood Hits	224
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LTB1L_HUMAN
θ value	6.21693e-09 (rank : 81)	NC score	0.585209 (rank : 53)
Query Neighborhood Hits	808	Target Neighborhood Hits	553	Shared Neighborhood Hits	360
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	6.21693e-09 (rank : 82)	NC score	0.582772 (rank : 56)
Query Neighborhood Hits	808	Target Neighborhood Hits	502	Shared Neighborhood Hits	341
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MATN2_MOUSE
θ value	8.11959e-09 (rank : 83)	NC score	0.507237 (rank : 114)
Query Neighborhood Hits	808	Target Neighborhood Hits	356	Shared Neighborhood Hits	251
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

CSPG2_HUMAN
θ value	1.06045e-08 (rank : 84)	NC score	0.371489 (rank : 218)
Query Neighborhood Hits	808	Target Neighborhood Hits	681	Shared Neighborhood Hits	291
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

DLL4_HUMAN
θ value	1.80886e-08 (rank : 85)	NC score	0.588977 (rank : 50)
Query Neighborhood Hits	808	Target Neighborhood Hits	435	Shared Neighborhood Hits	350
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

MAP4_MOUSE
θ value	1.80886e-08 (rank : 86)	NC score	0.184251 (rank : 381)
Query Neighborhood Hits	808	Target Neighborhood Hits	409	Shared Neighborhood Hits	65
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

STAB1_MOUSE
θ value	1.80886e-08 (rank : 87)	NC score	0.574193 (rank : 64)
Query Neighborhood Hits	808	Target Neighborhood Hits	566	Shared Neighborhood Hits	413
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

KR101_HUMAN
θ value	3.08544e-08 (rank : 88)	NC score	0.550562 (rank : 77)
Query Neighborhood Hits	808	Target Neighborhood Hits	261	Shared Neighborhood Hits	216
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

MAMC1_MOUSE
θ value	3.08544e-08 (rank : 89)	NC score	0.104256 (rank : 584)
Query Neighborhood Hits	808	Target Neighborhood Hits	357	Shared Neighborhood Hits	37
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

LAMA5_MOUSE
θ value	4.0297e-08 (rank : 90)	NC score	0.470285 (rank : 138)
Query Neighborhood Hits	808	Target Neighborhood Hits	828	Shared Neighborhood Hits	402
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LRP4_MOUSE
θ value	4.0297e-08 (rank : 91)	NC score	0.425599 (rank : 165)
Query Neighborhood Hits	808	Target Neighborhood Hits	351	Shared Neighborhood Hits	247
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LYAM3_MOUSE
θ value	4.0297e-08 (rank : 92)	NC score	0.326067 (rank : 258)
Query Neighborhood Hits	808	Target Neighborhood Hits	390	Shared Neighborhood Hits	245
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MAMC1_HUMAN
θ value	4.0297e-08 (rank : 93)	NC score	0.103083 (rank : 589)
Query Neighborhood Hits	808	Target Neighborhood Hits	357	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

CUBN_HUMAN
θ value	5.26297e-08 (rank : 94)	NC score	0.508316 (rank : 110)
Query Neighborhood Hits	808	Target Neighborhood Hits	482	Shared Neighborhood Hits	332
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

KR108_HUMAN
θ value	5.26297e-08 (rank : 95)	NC score	0.494991 (rank : 127)
Query Neighborhood Hits	808	Target Neighborhood Hits	226	Shared Neighborhood Hits	191
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

LAMA2_HUMAN
θ value	5.26297e-08 (rank : 96)	NC score	0.407190 (rank : 189)
Query Neighborhood Hits	808	Target Neighborhood Hits	1092	Shared Neighborhood Hits	361
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CRUM1_HUMAN
θ value	6.87365e-08 (rank : 97)	NC score	0.594730 (rank : 43)
Query Neighborhood Hits	808	Target Neighborhood Hits	457	Shared Neighborhood Hits	353
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

EMR1_MOUSE
θ value	6.87365e-08 (rank : 98)	NC score	0.428392 (rank : 161)
Query Neighborhood Hits	808	Target Neighborhood Hits	349	Shared Neighborhood Hits	227
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

LTBP3_MOUSE
θ value	6.87365e-08 (rank : 99)	NC score	0.583795 (rank : 54)
Query Neighborhood Hits	808	Target Neighborhood Hits	475	Shared Neighborhood Hits	351
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

TXND2_HUMAN
θ value	6.87365e-08 (rank : 100)	NC score	0.090016 (rank : 636)
Query Neighborhood Hits	808	Target Neighborhood Hits	793	Shared Neighborhood Hits	68
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

LRP4_HUMAN
θ value	8.97725e-08 (rank : 101)	NC score	0.424834 (rank : 167)
Query Neighborhood Hits	808	Target Neighborhood Hits	355	Shared Neighborhood Hits	252
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

DLL3_MOUSE
θ value	1.17247e-07 (rank : 102)	NC score	0.563904 (rank : 68)
Query Neighborhood Hits	808	Target Neighborhood Hits	399	Shared Neighborhood Hits	322
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

LDLR_MOUSE
θ value	1.17247e-07 (rank : 103)	NC score	0.468472 (rank : 139)
Query Neighborhood Hits	808	Target Neighborhood Hits	382	Shared Neighborhood Hits	281
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

FBLN1_MOUSE
θ value	1.53129e-07 (rank : 104)	NC score	0.550577 (rank : 76)
Query Neighborhood Hits	808	Target Neighborhood Hits	329	Shared Neighborhood Hits	269
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

KRA53_HUMAN
θ value	1.53129e-07 (rank : 105)	NC score	0.600815 (rank : 42)
Query Neighborhood Hits	808	Target Neighborhood Hits	331	Shared Neighborhood Hits	274
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

VLDLR_MOUSE
θ value	1.53129e-07 (rank : 106)	NC score	0.470922 (rank : 137)
Query Neighborhood Hits	808	Target Neighborhood Hits	360	Shared Neighborhood Hits	268
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

PTPRK_HUMAN
θ value	1.99992e-07 (rank : 107)	NC score	0.084717 (rank : 650)
Query Neighborhood Hits	808	Target Neighborhood Hits	228	Shared Neighborhood Hits	58
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

STAB2_MOUSE
θ value	1.99992e-07 (rank : 108)	NC score	0.559665 (rank : 71)
Query Neighborhood Hits	808	Target Neighborhood Hits	528	Shared Neighborhood Hits	388
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

PTPRK_MOUSE
θ value	2.61198e-07 (rank : 109)	NC score	0.085108 (rank : 648)
Query Neighborhood Hits	808	Target Neighborhood Hits	223	Shared Neighborhood Hits	57
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

LAMB3_MOUSE
θ value	3.41135e-07 (rank : 110)	NC score	0.386234 (rank : 200)
Query Neighborhood Hits	808	Target Neighborhood Hits	444	Shared Neighborhood Hits	243
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LR37A_HUMAN
θ value	3.41135e-07 (rank : 111)	NC score	0.122179 (rank : 530)
Query Neighborhood Hits	808	Target Neighborhood Hits	720	Shared Neighborhood Hits	97
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

STAB1_HUMAN
θ value	3.41135e-07 (rank : 112)	NC score	0.560839 (rank : 70)
Query Neighborhood Hits	808	Target Neighborhood Hits	546	Shared Neighborhood Hits	394
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

VLDLR_HUMAN
θ value	3.41135e-07 (rank : 113)	NC score	0.475937 (rank : 135)
Query Neighborhood Hits	808	Target Neighborhood Hits	383	Shared Neighborhood Hits	281
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

C1QR1_MOUSE
θ value	5.81887e-07 (rank : 114)	NC score	0.531962 (rank : 94)
Query Neighborhood Hits	808	Target Neighborhood Hits	342	Shared Neighborhood Hits	265
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

KR105_HUMAN
θ value	5.81887e-07 (rank : 115)	NC score	0.536182 (rank : 86)
Query Neighborhood Hits	808	Target Neighborhood Hits	271	Shared Neighborhood Hits	230
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

STAB2_HUMAN
θ value	5.81887e-07 (rank : 116)	NC score	0.554305 (rank : 75)
Query Neighborhood Hits	808	Target Neighborhood Hits	534	Shared Neighborhood Hits	386
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

ELF4_MOUSE
θ value	7.59969e-07 (rank : 117)	NC score	0.057889 (rank : 853)
Query Neighborhood Hits	808	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

MATN2_HUMAN
θ value	7.59969e-07 (rank : 118)	NC score	0.508411 (rank : 109)
Query Neighborhood Hits	808	Target Neighborhood Hits	365	Shared Neighborhood Hits	251
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

SON_MOUSE
θ value	7.59969e-07 (rank : 119)	NC score	0.144881 (rank : 463)
Query Neighborhood Hits	808	Target Neighborhood Hits	957	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CRUM2_HUMAN
θ value	9.92553e-07 (rank : 120)	NC score	0.591710 (rank : 46)
Query Neighborhood Hits	808	Target Neighborhood Hits	453	Shared Neighborhood Hits	350
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

MAGE1_HUMAN
θ value	9.92553e-07 (rank : 121)	NC score	0.098357 (rank : 604)
Query Neighborhood Hits	808	Target Neighborhood Hits	1389	Shared Neighborhood Hits	129
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

DLL1_HUMAN
θ value	1.29631e-06 (rank : 122)	NC score	0.590870 (rank : 47)
Query Neighborhood Hits	808	Target Neighborhood Hits	455	Shared Neighborhood Hits	371
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

LAMB1_HUMAN
θ value	1.29631e-06 (rank : 123)	NC score	0.382560 (rank : 208)
Query Neighborhood Hits	808	Target Neighborhood Hits	1018	Shared Neighborhood Hits	323
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LRP8_MOUSE
θ value	1.29631e-06 (rank : 124)	NC score	0.462278 (rank : 143)
Query Neighborhood Hits	808	Target Neighborhood Hits	385	Shared Neighborhood Hits	271
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

NRP2_HUMAN
θ value	1.29631e-06 (rank : 125)	NC score	0.133341 (rank : 487)
Query Neighborhood Hits	808	Target Neighborhood Hits	120	Shared Neighborhood Hits	53
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

CRUM1_MOUSE
θ value	1.69304e-06 (rank : 126)	NC score	0.589827 (rank : 48)
Query Neighborhood Hits	808	Target Neighborhood Hits	444	Shared Neighborhood Hits	350
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

LAMA2_MOUSE
θ value	1.69304e-06 (rank : 127)	NC score	0.386915 (rank : 199)
Query Neighborhood Hits	808	Target Neighborhood Hits	1198	Shared Neighborhood Hits	365
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

KR10C_HUMAN
θ value	2.21117e-06 (rank : 128)	NC score	0.484235 (rank : 132)
Query Neighborhood Hits	808	Target Neighborhood Hits	219	Shared Neighborhood Hits	186
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KRA51_HUMAN
θ value	2.88788e-06 (rank : 129)	NC score	0.546665 (rank : 79)
Query Neighborhood Hits	808	Target Neighborhood Hits	288	Shared Neighborhood Hits	223
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LAMB1_MOUSE
θ value	2.88788e-06 (rank : 130)	NC score	0.395667 (rank : 196)
Query Neighborhood Hits	808	Target Neighborhood Hits	919	Shared Neighborhood Hits	305
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LRP8_HUMAN
θ value	2.88788e-06 (rank : 131)	NC score	0.442003 (rank : 152)
Query Neighborhood Hits	808	Target Neighborhood Hits	346	Shared Neighborhood Hits	246
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

SUSD2_HUMAN
θ value	2.88788e-06 (rank : 132)	NC score	0.208134 (rank : 339)
Query Neighborhood Hits	808	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

TRBM_MOUSE
θ value	2.88788e-06 (rank : 133)	NC score	0.542956 (rank : 82)
Query Neighborhood Hits	808	Target Neighborhood Hits	361	Shared Neighborhood Hits	279
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

CORIN_HUMAN
θ value	3.77169e-06 (rank : 134)	NC score	0.195429 (rank : 362)
Query Neighborhood Hits	808	Target Neighborhood Hits	453	Shared Neighborhood Hits	214
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

LAMA1_MOUSE
θ value	3.77169e-06 (rank : 135)	NC score	0.450622 (rank : 147)
Query Neighborhood Hits	808	Target Neighborhood Hits	838	Shared Neighborhood Hits	365
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

TRBM_HUMAN
θ value	3.77169e-06 (rank : 136)	NC score	0.546454 (rank : 80)
Query Neighborhood Hits	808	Target Neighborhood Hits	339	Shared Neighborhood Hits	270
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

RECK_HUMAN
θ value	4.92598e-06 (rank : 137)	NC score	0.331227 (rank : 255)
Query Neighborhood Hits	808	Target Neighborhood Hits	189	Shared Neighborhood Hits	139
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

C1QR1_HUMAN
θ value	6.43352e-06 (rank : 138)	NC score	0.532762 (rank : 93)
Query Neighborhood Hits	808	Target Neighborhood Hits	493	Shared Neighborhood Hits	293
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CSMD1_HUMAN
θ value	6.43352e-06 (rank : 139)	NC score	0.104357 (rank : 582)
Query Neighborhood Hits	808	Target Neighborhood Hits	176	Shared Neighborhood Hits	68
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

EMR1_HUMAN
θ value	6.43352e-06 (rank : 140)	NC score	0.454912 (rank : 146)
Query Neighborhood Hits	808	Target Neighborhood Hits	382	Shared Neighborhood Hits	247
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

LAMC3_MOUSE
θ value	6.43352e-06 (rank : 141)	NC score	0.417070 (rank : 179)
Query Neighborhood Hits	808	Target Neighborhood Hits	624	Shared Neighborhood Hits	317
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

CUBN_MOUSE
θ value	8.40245e-06 (rank : 142)	NC score	0.510627 (rank : 107)
Query Neighborhood Hits	808	Target Neighborhood Hits	477	Shared Neighborhood Hits	332
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

FBLN1_HUMAN
θ value	8.40245e-06 (rank : 143)	NC score	0.549240 (rank : 78)
Query Neighborhood Hits	808	Target Neighborhood Hits	324	Shared Neighborhood Hits	270
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

KR102_HUMAN
θ value	8.40245e-06 (rank : 144)	NC score	0.536563 (rank : 85)
Query Neighborhood Hits	808	Target Neighborhood Hits	264	Shared Neighborhood Hits	224
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

TNR6B_HUMAN
θ value	8.40245e-06 (rank : 145)	NC score	0.135644 (rank : 483)
Query Neighborhood Hits	808	Target Neighborhood Hits	103	Shared Neighborhood Hits	67
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

CK024_MOUSE
θ value	1.09739e-05 (rank : 146)	NC score	0.171657 (rank : 413)
Query Neighborhood Hits	808	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

KR511_HUMAN
θ value	1.09739e-05 (rank : 147)	NC score	0.480275 (rank : 134)
Query Neighborhood Hits	808	Target Neighborhood Hits	231	Shared Neighborhood Hits	187
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

AMPH_HUMAN
θ value	1.43324e-05 (rank : 148)	NC score	0.069517 (rank : 735)
Query Neighborhood Hits	808	Target Neighborhood Hits	455	Shared Neighborhood Hits	43
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

CSPG3_HUMAN
θ value	1.43324e-05 (rank : 149)	NC score	0.345841 (rank : 243)
Query Neighborhood Hits	808	Target Neighborhood Hits	676	Shared Neighborhood Hits	274
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

MDC1_MOUSE
θ value	1.43324e-05 (rank : 150)	NC score	0.158610 (rank : 444)
Query Neighborhood Hits	808	Target Neighborhood Hits	998	Shared Neighborhood Hits	103
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MEGF8_MOUSE
θ value	1.43324e-05 (rank : 151)	NC score	0.502181 (rank : 118)
Query Neighborhood Hits	808	Target Neighborhood Hits	520	Shared Neighborhood Hits	335
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

OVGP1_MOUSE
θ value	1.43324e-05 (rank : 152)	NC score	0.046802 (rank : 948)
Query Neighborhood Hits	808	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	Q62010	Gene names	Ovgp1, Chit5, Ogp
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein).

RECK_MOUSE
θ value	1.43324e-05 (rank : 153)	NC score	0.302588 (rank : 269)
Query Neighborhood Hits	808	Target Neighborhood Hits	158	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

CSMD1_MOUSE
θ value	1.87187e-05 (rank : 154)	NC score	0.105159 (rank : 579)
Query Neighborhood Hits	808	Target Neighborhood Hits	193	Shared Neighborhood Hits	78
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CORIN_MOUSE
θ value	2.44474e-05 (rank : 155)	NC score	0.179467 (rank : 397)
Query Neighborhood Hits	808	Target Neighborhood Hits	451	Shared Neighborhood Hits	208
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

KR10A_HUMAN
θ value	2.44474e-05 (rank : 156)	NC score	0.438564 (rank : 153)
Query Neighborhood Hits	808	Target Neighborhood Hits	232	Shared Neighborhood Hits	196
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

LAMC1_MOUSE
θ value	2.44474e-05 (rank : 157)	NC score	0.384965 (rank : 202)
Query Neighborhood Hits	808	Target Neighborhood Hits	856	Shared Neighborhood Hits	315
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SON_HUMAN
θ value	2.44474e-05 (rank : 158)	NC score	0.116794 (rank : 542)
Query Neighborhood Hits	808	Target Neighborhood Hits	1568	Shared Neighborhood Hits	143
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

LAMA1_HUMAN
θ value	3.19293e-05 (rank : 159)	NC score	0.430933 (rank : 159)
Query Neighborhood Hits	808	Target Neighborhood Hits	804	Shared Neighborhood Hits	356
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

CELR1_HUMAN
θ value	4.1701e-05 (rank : 160)	NC score	0.254195 (rank : 288)
Query Neighborhood Hits	808	Target Neighborhood Hits	613	Shared Neighborhood Hits	299
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CREL1_HUMAN
θ value	4.1701e-05 (rank : 161)	NC score	0.541676 (rank : 83)
Query Neighborhood Hits	808	Target Neighborhood Hits	441	Shared Neighborhood Hits	272
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

DLK_MOUSE
θ value	4.1701e-05 (rank : 162)	NC score	0.574652 (rank : 63)
Query Neighborhood Hits	808	Target Neighborhood Hits	374	Shared Neighborhood Hits	327
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DNER_MOUSE
θ value	4.1701e-05 (rank : 163)	NC score	0.577946 (rank : 60)
Query Neighborhood Hits	808	Target Neighborhood Hits	413	Shared Neighborhood Hits	333
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

FATH_HUMAN
θ value	4.1701e-05 (rank : 164)	NC score	0.280595 (rank : 277)
Query Neighborhood Hits	808	Target Neighborhood Hits	570	Shared Neighborhood Hits	301
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

PTPRU_HUMAN
θ value	4.1701e-05 (rank : 165)	NC score	0.082898 (rank : 654)
Query Neighborhood Hits	808	Target Neighborhood Hits	237	Shared Neighborhood Hits	58
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

ADAM7_HUMAN
θ value	5.44631e-05 (rank : 166)	NC score	0.156176 (rank : 450)
Query Neighborhood Hits	808	Target Neighborhood Hits	221	Shared Neighborhood Hits	187
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

DNER_HUMAN
θ value	5.44631e-05 (rank : 167)	NC score	0.587799 (rank : 52)
Query Neighborhood Hits	808	Target Neighborhood Hits	460	Shared Neighborhood Hits	357
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

ITB2_MOUSE
θ value	5.44631e-05 (rank : 168)	NC score	0.354942 (rank : 231)
Query Neighborhood Hits	808	Target Neighborhood Hits	326	Shared Neighborhood Hits	281
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

NFH_MOUSE
θ value	5.44631e-05 (rank : 169)	NC score	0.041493 (rank : 968)
Query Neighborhood Hits	808	Target Neighborhood Hits	2247	Shared Neighborhood Hits	123
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NRP1_MOUSE
θ value	5.44631e-05 (rank : 170)	NC score	0.133992 (rank : 486)
Query Neighborhood Hits	808	Target Neighborhood Hits	120	Shared Neighborhood Hits	52
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

DLK_HUMAN
θ value	7.1131e-05 (rank : 171)	NC score	0.580309 (rank : 59)
Query Neighborhood Hits	808	Target Neighborhood Hits	401	Shared Neighborhood Hits	342
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

KRA54_HUMAN
θ value	7.1131e-05 (rank : 172)	NC score	0.500934 (rank : 120)
Query Neighborhood Hits	808	Target Neighborhood Hits	270	Shared Neighborhood Hits	213
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

MEGF8_HUMAN
θ value	7.1131e-05 (rank : 173)	NC score	0.507246 (rank : 113)
Query Neighborhood Hits	808	Target Neighborhood Hits	528	Shared Neighborhood Hits	339
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TSP2_HUMAN
θ value	7.1131e-05 (rank : 174)	NC score	0.347223 (rank : 242)
Query Neighborhood Hits	808	Target Neighborhood Hits	359	Shared Neighborhood Hits	270
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

EGFL9_HUMAN
θ value	9.29e-05 (rank : 175)	NC score	0.561218 (rank : 69)
Query Neighborhood Hits	808	Target Neighborhood Hits	365	Shared Neighborhood Hits	312
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

LAMA3_MOUSE
θ value	9.29e-05 (rank : 176)	NC score	0.375170 (rank : 216)
Query Neighborhood Hits	808	Target Neighborhood Hits	859	Shared Neighborhood Hits	348
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

USH2A_MOUSE
θ value	9.29e-05 (rank : 177)	NC score	0.402720 (rank : 192)
Query Neighborhood Hits	808	Target Neighborhood Hits	626	Shared Neighborhood Hits	339
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

DLL3_HUMAN
θ value	0.000121331 (rank : 178)	NC score	0.571793 (rank : 65)
Query Neighborhood Hits	808	Target Neighborhood Hits	419	Shared Neighborhood Hits	340
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

FLIP1_HUMAN
θ value	0.000121331 (rank : 179)	NC score	0.027353 (rank : 1006)
Query Neighborhood Hits	808	Target Neighborhood Hits	1405	Shared Neighborhood Hits	44
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

KRA58_HUMAN
θ value	0.000121331 (rank : 180)	NC score	0.575008 (rank : 62)
Query Neighborhood Hits	808	Target Neighborhood Hits	324	Shared Neighborhood Hits	261
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

NRP1_HUMAN
θ value	0.000121331 (rank : 181)	NC score	0.136807 (rank : 479)
Query Neighborhood Hits	808	Target Neighborhood Hits	119	Shared Neighborhood Hits	53
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

CELR2_MOUSE
θ value	0.000158464 (rank : 182)	NC score	0.244740 (rank : 301)
Query Neighborhood Hits	808	Target Neighborhood Hits	584	Shared Neighborhood Hits	297
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

ENTK_HUMAN
θ value	0.000158464 (rank : 183)	NC score	0.090146 (rank : 635)
Query Neighborhood Hits	808	Target Neighborhood Hits	310	Shared Neighborhood Hits	85
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

FINC_MOUSE
θ value	0.000158464 (rank : 184)	NC score	0.112085 (rank : 555)
Query Neighborhood Hits	808	Target Neighborhood Hits	309	Shared Neighborhood Hits	88
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

KRA15_HUMAN
θ value	0.000158464 (rank : 185)	NC score	0.381739 (rank : 209)
Query Neighborhood Hits	808	Target Neighborhood Hits	126	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

LAMC1_HUMAN
θ value	0.000158464 (rank : 186)	NC score	0.376035 (rank : 215)
Query Neighborhood Hits	808	Target Neighborhood Hits	922	Shared Neighborhood Hits	320
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LYAM3_HUMAN
θ value	0.000158464 (rank : 187)	NC score	0.291407 (rank : 271)
Query Neighborhood Hits	808	Target Neighborhood Hits	378	Shared Neighborhood Hits	234
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

TSP2_MOUSE
θ value	0.000158464 (rank : 188)	NC score	0.344572 (rank : 245)
Query Neighborhood Hits	808	Target Neighborhood Hits	352	Shared Neighborhood Hits	263
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

CELR2_HUMAN
θ value	0.00020696 (rank : 189)	NC score	0.273217 (rank : 280)
Query Neighborhood Hits	808	Target Neighborhood Hits	657	Shared Neighborhood Hits	342
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CSPG3_MOUSE
θ value	0.00020696 (rank : 190)	NC score	0.347668 (rank : 241)
Query Neighborhood Hits	808	Target Neighborhood Hits	657	Shared Neighborhood Hits	285
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

FBLN3_HUMAN
θ value	0.00020696 (rank : 191)	NC score	0.508105 (rank : 111)
Query Neighborhood Hits	808	Target Neighborhood Hits	293	Shared Neighborhood Hits	241
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

KRA55_HUMAN
θ value	0.00020696 (rank : 192)	NC score	0.493195 (rank : 129)
Query Neighborhood Hits	808	Target Neighborhood Hits	257	Shared Neighborhood Hits	207
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA92_HUMAN
θ value	0.00020696 (rank : 193)	NC score	0.413727 (rank : 183)
Query Neighborhood Hits	808	Target Neighborhood Hits	198	Shared Neighborhood Hits	169
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

SELPL_MOUSE
θ value	0.00020696 (rank : 194)	NC score	0.131132 (rank : 498)
Query Neighborhood Hits	808	Target Neighborhood Hits	588	Shared Neighborhood Hits	76
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

CRDL2_HUMAN
θ value	0.000270298 (rank : 195)	NC score	0.239527 (rank : 310)
Query Neighborhood Hits	808	Target Neighborhood Hits	99	Shared Neighborhood Hits	73
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

KR412_HUMAN
θ value	0.000270298 (rank : 196)	NC score	0.419301 (rank : 175)
Query Neighborhood Hits	808	Target Neighborhood Hits	178	Shared Neighborhood Hits	154
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA59_HUMAN
θ value	0.000270298 (rank : 197)	NC score	0.534675 (rank : 90)
Query Neighborhood Hits	808	Target Neighborhood Hits	310	Shared Neighborhood Hits	239
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

NID2_HUMAN
θ value	0.000270298 (rank : 198)	NC score	0.512505 (rank : 106)
Query Neighborhood Hits	808	Target Neighborhood Hits	456	Shared Neighborhood Hits	275
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

ST14_MOUSE
θ value	0.000270298 (rank : 199)	NC score	0.165306 (rank : 429)
Query Neighborhood Hits	808	Target Neighborhood Hits	419	Shared Neighborhood Hits	197
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

CELR3_HUMAN
θ value	0.00035302 (rank : 200)	NC score	0.268014 (rank : 282)
Query Neighborhood Hits	808	Target Neighborhood Hits	680	Shared Neighborhood Hits	319
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

LAMB2_HUMAN
θ value	0.00035302 (rank : 201)	NC score	0.426115 (rank : 164)
Query Neighborhood Hits	808	Target Neighborhood Hits	692	Shared Neighborhood Hits	319
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LYAM2_HUMAN
θ value	0.00035302 (rank : 202)	NC score	0.289188 (rank : 274)
Query Neighborhood Hits	808	Target Neighborhood Hits	394	Shared Neighborhood Hits	248
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

PCSK5_HUMAN
θ value	0.00035302 (rank : 203)	NC score	0.275301 (rank : 279)
Query Neighborhood Hits	808	Target Neighborhood Hits	291	Shared Neighborhood Hits	228
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

SLIT3_HUMAN
θ value	0.00035302 (rank : 204)	NC score	0.382840 (rank : 207)
Query Neighborhood Hits	808	Target Neighborhood Hits	682	Shared Neighborhood Hits	328
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SUSD2_MOUSE
θ value	0.00035302 (rank : 205)	NC score	0.211204 (rank : 332)
Query Neighborhood Hits	808	Target Neighborhood Hits	104	Shared Neighborhood Hits	41
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

AKA12_HUMAN
θ value	0.000461057 (rank : 206)	NC score	0.052736 (rank : 900)
Query Neighborhood Hits	808	Target Neighborhood Hits	825	Shared Neighborhood Hits	49
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ATS9_HUMAN
θ value	0.000461057 (rank : 207)	NC score	0.094891 (rank : 621)
Query Neighborhood Hits	808	Target Neighborhood Hits	219	Shared Neighborhood Hits	130
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

CYR61_HUMAN
θ value	0.000461057 (rank : 208)	NC score	0.182356 (rank : 390)
Query Neighborhood Hits	808	Target Neighborhood Hits	159	Shared Neighborhood Hits	105
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

FLIP1_MOUSE
θ value	0.000461057 (rank : 209)	NC score	0.032622 (rank : 990)
Query Neighborhood Hits	808	Target Neighborhood Hits	1176	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

ITB7_HUMAN
θ value	0.000461057 (rank : 210)	NC score	0.341617 (rank : 247)
Query Neighborhood Hits	808	Target Neighborhood Hits	290	Shared Neighborhood Hits	250
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

LAD1_MOUSE
θ value	0.000461057 (rank : 211)	NC score	0.076338 (rank : 690)
Query Neighborhood Hits	808	Target Neighborhood Hits	391	Shared Neighborhood Hits	49
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

ALMS1_HUMAN
θ value	0.000602161 (rank : 212)	NC score	0.089695 (rank : 638)
Query Neighborhood Hits	808	Target Neighborhood Hits	356	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

HGFA_MOUSE
θ value	0.000602161 (rank : 213)	NC score	0.185888 (rank : 377)
Query Neighborhood Hits	808	Target Neighborhood Hits	419	Shared Neighborhood Hits	213
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

MEGF9_MOUSE
θ value	0.000602161 (rank : 214)	NC score	0.446799 (rank : 150)
Query Neighborhood Hits	808	Target Neighborhood Hits	896	Shared Neighborhood Hits	321
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PCSK6_HUMAN
θ value	0.000602161 (rank : 215)	NC score	0.246341 (rank : 299)
Query Neighborhood Hits	808	Target Neighborhood Hits	298	Shared Neighborhood Hits	188
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

RTN4_MOUSE
θ value	0.000602161 (rank : 216)	NC score	0.071267 (rank : 722)
Query Neighborhood Hits	808	Target Neighborhood Hits	341	Shared Neighborhood Hits	44
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SLIT2_HUMAN
θ value	0.000602161 (rank : 217)	NC score	0.402331 (rank : 193)
Query Neighborhood Hits	808	Target Neighborhood Hits	708	Shared Neighborhood Hits	359
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	0.000602161 (rank : 218)	NC score	0.395122 (rank : 197)
Query Neighborhood Hits	808	Target Neighborhood Hits	684	Shared Neighborhood Hits	338
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

USH2A_HUMAN
θ value	0.000602161 (rank : 219)	NC score	0.369428 (rank : 219)
Query Neighborhood Hits	808	Target Neighborhood Hits	600	Shared Neighborhood Hits	311
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

ADM1A_MOUSE
θ value	0.000786445 (rank : 220)	NC score	0.152409 (rank : 456)
Query Neighborhood Hits	808	Target Neighborhood Hits	230	Shared Neighborhood Hits	193
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

CD97_HUMAN
θ value	0.000786445 (rank : 221)	NC score	0.421978 (rank : 168)
Query Neighborhood Hits	808	Target Neighborhood Hits	353	Shared Neighborhood Hits	237
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CHRD_HUMAN
θ value	0.000786445 (rank : 222)	NC score	0.231518 (rank : 313)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

COMP_MOUSE
θ value	0.000786445 (rank : 223)	NC score	0.424847 (rank : 166)
Query Neighborhood Hits	808	Target Neighborhood Hits	290	Shared Neighborhood Hits	247
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CREL1_MOUSE
θ value	0.000786445 (rank : 224)	NC score	0.533377 (rank : 91)
Query Neighborhood Hits	808	Target Neighborhood Hits	524	Shared Neighborhood Hits	289
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

KR103_HUMAN
θ value	0.000786445 (rank : 225)	NC score	0.419782 (rank : 173)
Query Neighborhood Hits	808	Target Neighborhood Hits	212	Shared Neighborhood Hits	187
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KRA98_HUMAN
θ value	0.000786445 (rank : 226)	NC score	0.417700 (rank : 177)
Query Neighborhood Hits	808	Target Neighborhood Hits	185	Shared Neighborhood Hits	155
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

MCSP_MOUSE
θ value	0.000786445 (rank : 227)	NC score	0.261502 (rank : 286)
Query Neighborhood Hits	808	Target Neighborhood Hits	108	Shared Neighborhood Hits	77
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

NID2_MOUSE
θ value	0.000786445 (rank : 228)	NC score	0.506203 (rank : 116)
Query Neighborhood Hits	808	Target Neighborhood Hits	338	Shared Neighborhood Hits	257
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

FST_MOUSE
θ value	0.00102713 (rank : 229)	NC score	0.203273 (rank : 349)
Query Neighborhood Hits	808	Target Neighborhood Hits	146	Shared Neighborhood Hits	92
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

KRA13_HUMAN
θ value	0.00102713 (rank : 230)	NC score	0.432376 (rank : 158)
Query Neighborhood Hits	808	Target Neighborhood Hits	144	Shared Neighborhood Hits	125
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA94_HUMAN
θ value	0.00102713 (rank : 231)	NC score	0.436906 (rank : 155)
Query Neighborhood Hits	808	Target Neighborhood Hits	204	Shared Neighborhood Hits	183
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

PGCB_MOUSE
θ value	0.00102713 (rank : 232)	NC score	0.212990 (rank : 328)
Query Neighborhood Hits	808	Target Neighborhood Hits	459	Shared Neighborhood Hits	195
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PROS_MOUSE
θ value	0.00102713 (rank : 233)	NC score	0.494334 (rank : 128)
Query Neighborhood Hits	808	Target Neighborhood Hits	330	Shared Neighborhood Hits	278
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

ADA32_HUMAN
θ value	0.00134147 (rank : 234)	NC score	0.138910 (rank : 471)
Query Neighborhood Hits	808	Target Neighborhood Hits	216	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

CYR61_MOUSE
θ value	0.00134147 (rank : 235)	NC score	0.183350 (rank : 387)
Query Neighborhood Hits	808	Target Neighborhood Hits	156	Shared Neighborhood Hits	101
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

EDIL3_MOUSE
θ value	0.00134147 (rank : 236)	NC score	0.430000 (rank : 160)
Query Neighborhood Hits	808	Target Neighborhood Hits	317	Shared Neighborhood Hits	260
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

FBLN5_MOUSE
θ value	0.00134147 (rank : 237)	NC score	0.516377 (rank : 104)
Query Neighborhood Hits	808	Target Neighborhood Hits	317	Shared Neighborhood Hits	253
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

LAMC2_HUMAN
θ value	0.00134147 (rank : 238)	NC score	0.373237 (rank : 217)
Query Neighborhood Hits	808	Target Neighborhood Hits	715	Shared Neighborhood Hits	295
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

TNR8_HUMAN
θ value	0.00134147 (rank : 239)	NC score	0.182700 (rank : 389)
Query Neighborhood Hits	808	Target Neighborhood Hits	198	Shared Neighborhood Hits	114
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

CRDL2_MOUSE
θ value	0.00175202 (rank : 240)	NC score	0.242389 (rank : 306)
Query Neighborhood Hits	808	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

EMR2_HUMAN
θ value	0.00175202 (rank : 241)	NC score	0.426424 (rank : 163)
Query Neighborhood Hits	808	Target Neighborhood Hits	345	Shared Neighborhood Hits	233
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

KRA11_HUMAN
θ value	0.00175202 (rank : 242)	NC score	0.383619 (rank : 205)
Query Neighborhood Hits	808	Target Neighborhood Hits	155	Shared Neighborhood Hits	129
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA45_HUMAN
θ value	0.00175202 (rank : 243)	NC score	0.434036 (rank : 156)
Query Neighborhood Hits	808	Target Neighborhood Hits	194	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA57_HUMAN
θ value	0.00175202 (rank : 244)	NC score	0.519766 (rank : 101)
Query Neighborhood Hits	808	Target Neighborhood Hits	269	Shared Neighborhood Hits	224
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

MAP1B_HUMAN
θ value	0.00175202 (rank : 245)	NC score	0.063271 (rank : 788)
Query Neighborhood Hits	808	Target Neighborhood Hits	903	Shared Neighborhood Hits	69
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MFGM_MOUSE
θ value	0.00175202 (rank : 246)	NC score	0.325364 (rank : 259)
Query Neighborhood Hits	808	Target Neighborhood Hits	233	Shared Neighborhood Hits	188
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

NRP2_MOUSE
θ value	0.00175202 (rank : 247)	NC score	0.119305 (rank : 537)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PROS_HUMAN
θ value	0.00175202 (rank : 248)	NC score	0.498021 (rank : 122)
Query Neighborhood Hits	808	Target Neighborhood Hits	340	Shared Neighborhood Hits	276
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SLIT1_HUMAN
θ value	0.00175202 (rank : 249)	NC score	0.414121 (rank : 182)
Query Neighborhood Hits	808	Target Neighborhood Hits	700	Shared Neighborhood Hits	350
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

ST14_HUMAN
θ value	0.00175202 (rank : 250)	NC score	0.159102 (rank : 443)
Query Neighborhood Hits	808	Target Neighborhood Hits	409	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

CELR3_MOUSE
θ value	0.00228821 (rank : 251)	NC score	0.266541 (rank : 283)
Query Neighborhood Hits	808	Target Neighborhood Hits	687	Shared Neighborhood Hits	335
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CN037_HUMAN
θ value	0.00228821 (rank : 252)	NC score	0.092709 (rank : 629)
Query Neighborhood Hits	808	Target Neighborhood Hits	118	Shared Neighborhood Hits	24
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

ENTK_MOUSE
θ value	0.00228821 (rank : 253)	NC score	0.096720 (rank : 612)
Query Neighborhood Hits	808	Target Neighborhood Hits	338	Shared Neighborhood Hits	93
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

FST_HUMAN
θ value	0.00228821 (rank : 254)	NC score	0.189570 (rank : 371)
Query Neighborhood Hits	808	Target Neighborhood Hits	129	Shared Neighborhood Hits	74
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

KRA52_HUMAN
θ value	0.00228821 (rank : 255)	NC score	0.458980 (rank : 145)
Query Neighborhood Hits	808	Target Neighborhood Hits	236	Shared Neighborhood Hits	196
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LAMC3_HUMAN
θ value	0.00228821 (rank : 256)	NC score	0.417040 (rank : 180)
Query Neighborhood Hits	808	Target Neighborhood Hits	588	Shared Neighborhood Hits	331
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

PROZ_MOUSE
θ value	0.00228821 (rank : 257)	NC score	0.359599 (rank : 225)
Query Neighborhood Hits	808	Target Neighborhood Hits	410	Shared Neighborhood Hits	237
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FA12_HUMAN
θ value	0.00298849 (rank : 258)	NC score	0.173207 (rank : 410)
Query Neighborhood Hits	808	Target Neighborhood Hits	425	Shared Neighborhood Hits	209
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FSTL3_HUMAN
θ value	0.00298849 (rank : 259)	NC score	0.197800 (rank : 358)
Query Neighborhood Hits	808	Target Neighborhood Hits	162	Shared Neighborhood Hits	108
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

KR414_HUMAN
θ value	0.00298849 (rank : 260)	NC score	0.417500 (rank : 178)
Query Neighborhood Hits	808	Target Neighborhood Hits	199	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

SLIT1_MOUSE
θ value	0.00298849 (rank : 261)	NC score	0.405381 (rank : 190)
Query Neighborhood Hits	808	Target Neighborhood Hits	715	Shared Neighborhood Hits	357
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

WISP2_MOUSE
θ value	0.00298849 (rank : 262)	NC score	0.188532 (rank : 372)
Query Neighborhood Hits	808	Target Neighborhood Hits	129	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

CNTP1_HUMAN
θ value	0.00390308 (rank : 263)	NC score	0.176009 (rank : 403)
Query Neighborhood Hits	808	Target Neighborhood Hits	196	Shared Neighborhood Hits	127
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

ITB2_HUMAN
θ value	0.00390308 (rank : 264)	NC score	0.323205 (rank : 261)
Query Neighborhood Hits	808	Target Neighborhood Hits	282	Shared Neighborhood Hits	241
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

PGBM_MOUSE
θ value	0.00390308 (rank : 265)	NC score	0.353180 (rank : 234)
Query Neighborhood Hits	808	Target Neighborhood Hits	1073	Shared Neighborhood Hits	385
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TIE1_MOUSE
θ value	0.00390308 (rank : 266)	NC score	0.155987 (rank : 451)
Query Neighborhood Hits	808	Target Neighborhood Hits	1266	Shared Neighborhood Hits	302
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

WIF1_HUMAN
θ value	0.00390308 (rank : 267)	NC score	0.557473 (rank : 73)
Query Neighborhood Hits	808	Target Neighborhood Hits	392	Shared Neighborhood Hits	340
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CNTP1_MOUSE
θ value	0.00509761 (rank : 268)	NC score	0.171171 (rank : 414)
Query Neighborhood Hits	808	Target Neighborhood Hits	183	Shared Neighborhood Hits	122
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

FBLN4_MOUSE
θ value	0.00509761 (rank : 269)	NC score	0.507768 (rank : 112)
Query Neighborhood Hits	808	Target Neighborhood Hits	270	Shared Neighborhood Hits	220
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	0.00509761 (rank : 270)	NC score	0.519361 (rank : 102)
Query Neighborhood Hits	808	Target Neighborhood Hits	329	Shared Neighborhood Hits	267
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

HABP2_MOUSE
θ value	0.00509761 (rank : 271)	NC score	0.229735 (rank : 315)
Query Neighborhood Hits	808	Target Neighborhood Hits	445	Shared Neighborhood Hits	248
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

INSR_MOUSE
θ value	0.00509761 (rank : 272)	NC score	0.039652 (rank : 974)
Query Neighborhood Hits	808	Target Neighborhood Hits	968	Shared Neighborhood Hits	134
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

ITB5_MOUSE
θ value	0.00509761 (rank : 273)	NC score	0.360264 (rank : 224)
Query Neighborhood Hits	808	Target Neighborhood Hits	329	Shared Neighborhood Hits	287
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

KR510_HUMAN
θ value	0.00509761 (rank : 274)	NC score	0.418658 (rank : 176)
Query Neighborhood Hits	808	Target Neighborhood Hits	217	Shared Neighborhood Hits	172
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA42_HUMAN
θ value	0.00509761 (rank : 275)	NC score	0.335278 (rank : 251)
Query Neighborhood Hits	808	Target Neighborhood Hits	149	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA99_HUMAN
θ value	0.00509761 (rank : 276)	NC score	0.377058 (rank : 214)
Query Neighborhood Hits	808	Target Neighborhood Hits	173	Shared Neighborhood Hits	149
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

MLL3_MOUSE
θ value	0.00509761 (rank : 277)	NC score	0.078525 (rank : 676)
Query Neighborhood Hits	808	Target Neighborhood Hits	1399	Shared Neighborhood Hits	157
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NID1_HUMAN
θ value	0.00509761 (rank : 278)	NC score	0.499354 (rank : 121)
Query Neighborhood Hits	808	Target Neighborhood Hits	329	Shared Neighborhood Hits	259
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TENN_MOUSE
θ value	0.00509761 (rank : 279)	NC score	0.290213 (rank : 272)
Query Neighborhood Hits	808	Target Neighborhood Hits	484	Shared Neighborhood Hits	287
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TR10D_HUMAN
θ value	0.00509761 (rank : 280)	NC score	0.077001 (rank : 685)
Query Neighborhood Hits	808	Target Neighborhood Hits	62	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TSP1_HUMAN
θ value	0.00509761 (rank : 281)	NC score	0.384776 (rank : 203)
Query Neighborhood Hits	808	Target Neighborhood Hits	389	Shared Neighborhood Hits	281
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

FBLN3_MOUSE
θ value	0.00665767 (rank : 282)	NC score	0.497743 (rank : 124)
Query Neighborhood Hits	808	Target Neighborhood Hits	279	Shared Neighborhood Hits	228
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FSTL3_MOUSE
θ value	0.00665767 (rank : 283)	NC score	0.198611 (rank : 357)
Query Neighborhood Hits	808	Target Neighborhood Hits	152	Shared Neighborhood Hits	104
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

ITB3_HUMAN
θ value	0.00665767 (rank : 284)	NC score	0.352321 (rank : 235)
Query Neighborhood Hits	808	Target Neighborhood Hits	325	Shared Neighborhood Hits	284
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

KRA47_HUMAN
θ value	0.00665767 (rank : 285)	NC score	0.436953 (rank : 154)
Query Neighborhood Hits	808	Target Neighborhood Hits	204	Shared Neighborhood Hits	172
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

TNR25_HUMAN
θ value	0.00665767 (rank : 286)	NC score	0.212516 (rank : 329)
Query Neighborhood Hits	808	Target Neighborhood Hits	172	Shared Neighborhood Hits	103
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR9_HUMAN
θ value	0.00665767 (rank : 287)	NC score	0.196475 (rank : 360)
Query Neighborhood Hits	808	Target Neighborhood Hits	166	Shared Neighborhood Hits	118
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TSP1_MOUSE
θ value	0.00665767 (rank : 288)	NC score	0.383538 (rank : 206)
Query Neighborhood Hits	808	Target Neighborhood Hits	396	Shared Neighborhood Hits	285
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

UROM_HUMAN
θ value	0.00665767 (rank : 289)	NC score	0.521574 (rank : 99)
Query Neighborhood Hits	808	Target Neighborhood Hits	284	Shared Neighborhood Hits	237
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	0.00665767 (rank : 290)	NC score	0.519795 (rank : 100)
Query Neighborhood Hits	808	Target Neighborhood Hits	276	Shared Neighborhood Hits	233
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

EGF_HUMAN
θ value	0.00869519 (rank : 291)	NC score	0.483094 (rank : 133)
Query Neighborhood Hits	808	Target Neighborhood Hits	343	Shared Neighborhood Hits	265
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	0.00869519 (rank : 292)	NC score	0.496747 (rank : 126)
Query Neighborhood Hits	808	Target Neighborhood Hits	358	Shared Neighborhood Hits	284
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

HABP2_HUMAN
θ value	0.00869519 (rank : 293)	NC score	0.231703 (rank : 312)
Query Neighborhood Hits	808	Target Neighborhood Hits	431	Shared Neighborhood Hits	242
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HCFC1_MOUSE
θ value	0.00869519 (rank : 294)	NC score	0.101412 (rank : 595)
Query Neighborhood Hits	808	Target Neighborhood Hits	348	Shared Neighborhood Hits	72
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

ITB5_HUMAN
θ value	0.00869519 (rank : 295)	NC score	0.343613 (rank : 246)
Query Neighborhood Hits	808	Target Neighborhood Hits	310	Shared Neighborhood Hits	269
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

KRA44_HUMAN
θ value	0.00869519 (rank : 296)	NC score	0.398909 (rank : 194)
Query Neighborhood Hits	808	Target Neighborhood Hits	162	Shared Neighborhood Hits	143
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

LAMA3_HUMAN
θ value	0.00869519 (rank : 297)	NC score	0.310248 (rank : 268)
Query Neighborhood Hits	808	Target Neighborhood Hits	760	Shared Neighborhood Hits	264
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

OVGP1_HUMAN
θ value	0.00869519 (rank : 298)	NC score	0.054388 (rank : 877)
Query Neighborhood Hits	808	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q12889, Q15841	Gene names	OVGP1, MUC9, OGP
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein) (Mucin 9).

PGCB_HUMAN
θ value	0.00869519 (rank : 299)	NC score	0.199728 (rank : 353)
Query Neighborhood Hits	808	Target Neighborhood Hits	478	Shared Neighborhood Hits	199
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

EDIL3_HUMAN
θ value	0.0113563 (rank : 300)	NC score	0.420991 (rank : 171)
Query Neighborhood Hits	808	Target Neighborhood Hits	292	Shared Neighborhood Hits	242
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

FBLN4_HUMAN
θ value	0.0113563 (rank : 301)	NC score	0.514064 (rank : 105)
Query Neighborhood Hits	808	Target Neighborhood Hits	278	Shared Neighborhood Hits	228
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

NAGPA_MOUSE
θ value	0.0113563 (rank : 302)	NC score	0.447836 (rank : 148)
Query Neighborhood Hits	808	Target Neighborhood Hits	308	Shared Neighborhood Hits	276
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

PME17_HUMAN
θ value	0.0113563 (rank : 303)	NC score	0.085578 (rank : 646)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	30
SwissProt Accessions	P40967, Q12763, Q14448, Q14817, Q16565	Gene names	SILV, D12S53E, PMEL17
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Melanocyte lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (ME20M/ME20S) (ME20- M/ME20-S) (95 kDa melanocyte-specific secreted glycoprotein).

TNR14_HUMAN
θ value	0.0113563 (rank : 304)	NC score	0.162387 (rank : 434)
Query Neighborhood Hits	808	Target Neighborhood Hits	149	Shared Neighborhood Hits	101
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

VEGFC_HUMAN
θ value	0.0113563 (rank : 305)	NC score	0.182827 (rank : 388)
Query Neighborhood Hits	808	Target Neighborhood Hits	128	Shared Neighborhood Hits	105
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

EGFL9_MOUSE
θ value	0.0148317 (rank : 306)	NC score	0.559534 (rank : 72)
Query Neighborhood Hits	808	Target Neighborhood Hits	379	Shared Neighborhood Hits	319
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

HCFC1_HUMAN
θ value	0.0148317 (rank : 307)	NC score	0.104291 (rank : 583)
Query Neighborhood Hits	808	Target Neighborhood Hits	331	Shared Neighborhood Hits	74
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

LAMB3_HUMAN
θ value	0.0148317 (rank : 308)	NC score	0.351817 (rank : 238)
Query Neighborhood Hits	808	Target Neighborhood Hits	461	Shared Neighborhood Hits	212
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMC2_MOUSE
θ value	0.0148317 (rank : 309)	NC score	0.385191 (rank : 201)
Query Neighborhood Hits	808	Target Neighborhood Hits	614	Shared Neighborhood Hits	306
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

SLIT3_MOUSE
θ value	0.0148317 (rank : 310)	NC score	0.397360 (rank : 195)
Query Neighborhood Hits	808	Target Neighborhood Hits	700	Shared Neighborhood Hits	344
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TNR21_MOUSE
θ value	0.0148317 (rank : 311)	NC score	0.126604 (rank : 510)
Query Neighborhood Hits	808	Target Neighborhood Hits	108	Shared Neighborhood Hits	66
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

WIF1_MOUSE
θ value	0.0148317 (rank : 312)	NC score	0.555377 (rank : 74)
Query Neighborhood Hits	808	Target Neighborhood Hits	393	Shared Neighborhood Hits	335
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ADA17_HUMAN
θ value	0.0193708 (rank : 313)	NC score	0.177917 (rank : 400)
Query Neighborhood Hits	808	Target Neighborhood Hits	223	Shared Neighborhood Hits	172
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ITB6_MOUSE
θ value	0.0193708 (rank : 314)	NC score	0.362770 (rank : 223)
Query Neighborhood Hits	808	Target Neighborhood Hits	341	Shared Neighborhood Hits	278
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

KRA93_HUMAN
θ value	0.0193708 (rank : 315)	NC score	0.411469 (rank : 186)
Query Neighborhood Hits	808	Target Neighborhood Hits	203	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

MEGF9_HUMAN
θ value	0.0193708 (rank : 316)	NC score	0.472080 (rank : 136)
Query Neighborhood Hits	808	Target Neighborhood Hits	557	Shared Neighborhood Hits	342
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MSMB_HUMAN
θ value	0.0193708 (rank : 317)	NC score	0.093501 (rank : 626)
Query Neighborhood Hits	808	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	P08118, P11999, Q13125, Q9UC59	Gene names	MSMB, PRSP
Domain Architecture
Description	Beta-microseminoprotein precursor (Prostate secreted seminal plasma protein) (Prostate secretory protein PSP94) (PSP-94) (Seminal plasma beta-inhibin) (Immunoglobulin-binding factor) (IGBF) (PN44).

MT4_HUMAN
θ value	0.0193708 (rank : 318)	NC score	0.208183 (rank : 338)
Query Neighborhood Hits	808	Target Neighborhood Hits	83	Shared Neighborhood Hits	69
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

NOV_HUMAN
θ value	0.0193708 (rank : 319)	NC score	0.187097 (rank : 375)
Query Neighborhood Hits	808	Target Neighborhood Hits	128	Shared Neighborhood Hits	84
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NRX1A_HUMAN
θ value	0.0193708 (rank : 320)	NC score	0.199834 (rank : 352)
Query Neighborhood Hits	808	Target Neighborhood Hits	170	Shared Neighborhood Hits	132
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	0.0193708 (rank : 321)	NC score	0.199314 (rank : 355)
Query Neighborhood Hits	808	Target Neighborhood Hits	164	Shared Neighborhood Hits	131
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

PAPPA_HUMAN
θ value	0.0193708 (rank : 322)	NC score	0.132155 (rank : 493)
Query Neighborhood Hits	808	Target Neighborhood Hits	161	Shared Neighborhood Hits	83
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PGBM_HUMAN
θ value	0.0193708 (rank : 323)	NC score	0.339966 (rank : 249)
Query Neighborhood Hits	808	Target Neighborhood Hits	1113	Shared Neighborhood Hits	386
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGH2_MOUSE
θ value	0.0193708 (rank : 324)	NC score	0.155963 (rank : 452)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	101
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

ADA17_MOUSE
θ value	0.0252991 (rank : 325)	NC score	0.152811 (rank : 454)
Query Neighborhood Hits	808	Target Neighborhood Hits	201	Shared Neighborhood Hits	160
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA24_MOUSE
θ value	0.0252991 (rank : 326)	NC score	0.133039 (rank : 489)
Query Neighborhood Hits	808	Target Neighborhood Hits	230	Shared Neighborhood Hits	183
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

COMP_HUMAN
θ value	0.0252991 (rank : 327)	NC score	0.402958 (rank : 191)
Query Neighborhood Hits	808	Target Neighborhood Hits	258	Shared Neighborhood Hits	221
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CSMD3_HUMAN
θ value	0.0252991 (rank : 328)	NC score	0.096736 (rank : 611)
Query Neighborhood Hits	808	Target Neighborhood Hits	199	Shared Neighborhood Hits	73
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

FA47B_HUMAN
θ value	0.0252991 (rank : 329)	NC score	0.063232 (rank : 790)
Query Neighborhood Hits	808	Target Neighborhood Hits	431	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GAS6_MOUSE
θ value	0.0252991 (rank : 330)	NC score	0.497981 (rank : 123)
Query Neighborhood Hits	808	Target Neighborhood Hits	343	Shared Neighborhood Hits	279
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

KRA56_HUMAN
θ value	0.0252991 (rank : 331)	NC score	0.461608 (rank : 144)
Query Neighborhood Hits	808	Target Neighborhood Hits	207	Shared Neighborhood Hits	173
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LAMB2_MOUSE
θ value	0.0252991 (rank : 332)	NC score	0.421623 (rank : 169)
Query Neighborhood Hits	808	Target Neighborhood Hits	722	Shared Neighborhood Hits	316
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

MAVS_HUMAN
θ value	0.0252991 (rank : 333)	NC score	0.107549 (rank : 570)
Query Neighborhood Hits	808	Target Neighborhood Hits	271	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

NAGPA_HUMAN
θ value	0.0252991 (rank : 334)	NC score	0.447035 (rank : 149)
Query Neighborhood Hits	808	Target Neighborhood Hits	282	Shared Neighborhood Hits	249
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NOV_MOUSE
θ value	0.0252991 (rank : 335)	NC score	0.166637 (rank : 424)
Query Neighborhood Hits	808	Target Neighborhood Hits	130	Shared Neighborhood Hits	85
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

TR11B_HUMAN
θ value	0.0252991 (rank : 336)	NC score	0.096372 (rank : 613)
Query Neighborhood Hits	808	Target Neighborhood Hits	92	Shared Neighborhood Hits	57
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

WISP2_HUMAN
θ value	0.0252991 (rank : 337)	NC score	0.183954 (rank : 383)
Query Neighborhood Hits	808	Target Neighborhood Hits	126	Shared Neighborhood Hits	76
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

ZNFX1_HUMAN
θ value	0.0252991 (rank : 338)	NC score	0.215972 (rank : 325)
Query Neighborhood Hits	808	Target Neighborhood Hits	308	Shared Neighborhood Hits	160
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ADA12_MOUSE
θ value	0.0330416 (rank : 339)	NC score	0.131460 (rank : 495)
Query Neighborhood Hits	808	Target Neighborhood Hits	474	Shared Neighborhood Hits	165
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM7_MOUSE
θ value	0.0330416 (rank : 340)	NC score	0.128533 (rank : 507)
Query Neighborhood Hits	808	Target Neighborhood Hits	200	Shared Neighborhood Hits	155
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

CELR1_MOUSE
θ value	0.0330416 (rank : 341)	NC score	0.252200 (rank : 292)
Query Neighborhood Hits	808	Target Neighborhood Hits	617	Shared Neighborhood Hits	301
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

FAT2_HUMAN
θ value	0.0330416 (rank : 342)	NC score	0.176701 (rank : 402)
Query Neighborhood Hits	808	Target Neighborhood Hits	507	Shared Neighborhood Hits	218
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

INSR_HUMAN
θ value	0.0330416 (rank : 343)	NC score	0.041026 (rank : 969)
Query Neighborhood Hits	808	Target Neighborhood Hits	963	Shared Neighborhood Hits	135
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

MINT_MOUSE
θ value	0.0330416 (rank : 344)	NC score	0.060445 (rank : 820)
Query Neighborhood Hits	808	Target Neighborhood Hits	1514	Shared Neighborhood Hits	108
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ZEP1_HUMAN
θ value	0.0330416 (rank : 345)	NC score	0.004052 (rank : 1105)
Query Neighborhood Hits	808	Target Neighborhood Hits	1036	Shared Neighborhood Hits	46
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ADAM8_MOUSE
θ value	0.0431538 (rank : 346)	NC score	0.190345 (rank : 368)
Query Neighborhood Hits	808	Target Neighborhood Hits	326	Shared Neighborhood Hits	231
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADM1B_MOUSE
θ value	0.0431538 (rank : 347)	NC score	0.138867 (rank : 472)
Query Neighborhood Hits	808	Target Neighborhood Hits	236	Shared Neighborhood Hits	165
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ATF2_HUMAN
θ value	0.0431538 (rank : 348)	NC score	0.058676 (rank : 841)
Query Neighborhood Hits	808	Target Neighborhood Hits	402	Shared Neighborhood Hits	32
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	0.0431538 (rank : 349)	NC score	0.057072 (rank : 858)
Query Neighborhood Hits	808	Target Neighborhood Hits	397	Shared Neighborhood Hits	31
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

CD45_HUMAN
θ value	0.0431538 (rank : 350)	NC score	0.050453 (rank : 931)
Query Neighborhood Hits	808	Target Neighborhood Hits	243	Shared Neighborhood Hits	48
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD97_MOUSE
θ value	0.0431538 (rank : 351)	NC score	0.366074 (rank : 222)
Query Neighborhood Hits	808	Target Neighborhood Hits	295	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CHRD_MOUSE
θ value	0.0431538 (rank : 352)	NC score	0.217031 (rank : 323)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

EMSY_MOUSE
θ value	0.0431538 (rank : 353)	NC score	0.079036 (rank : 672)
Query Neighborhood Hits	808	Target Neighborhood Hits	294	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

HNF1A_HUMAN
θ value	0.0431538 (rank : 354)	NC score	0.054149 (rank : 879)
Query Neighborhood Hits	808	Target Neighborhood Hits	193	Shared Neighborhood Hits	29
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

ITB6_HUMAN
θ value	0.0431538 (rank : 355)	NC score	0.348335 (rank : 240)
Query Neighborhood Hits	808	Target Neighborhood Hits	318	Shared Neighborhood Hits	271
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

LAMA4_MOUSE
θ value	0.0431538 (rank : 356)	NC score	0.319403 (rank : 265)
Query Neighborhood Hits	808	Target Neighborhood Hits	584	Shared Neighborhood Hits	227
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LY6D_MOUSE
θ value	0.0431538 (rank : 357)	NC score	0.048426 (rank : 944)
Query Neighborhood Hits	808	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	P35459	Gene names	Ly6d, Ly61, Thb
Domain Architecture
Description	Lymphocyte antigen Ly-6D precursor (Thymocyte B-cell antigen) (ThB).

MT4_MOUSE
θ value	0.0431538 (rank : 358)	NC score	0.243293 (rank : 305)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

PTPRM_HUMAN
θ value	0.0431538 (rank : 359)	NC score	0.071589 (rank : 717)
Query Neighborhood Hits	808	Target Neighborhood Hits	244	Shared Neighborhood Hits	57
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRT_HUMAN
θ value	0.0431538 (rank : 360)	NC score	0.072368 (rank : 711)
Query Neighborhood Hits	808	Target Neighborhood Hits	217	Shared Neighborhood Hits	56
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	0.0431538 (rank : 361)	NC score	0.072577 (rank : 708)
Query Neighborhood Hits	808	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

TENR_HUMAN
θ value	0.0431538 (rank : 362)	NC score	0.334376 (rank : 252)
Query Neighborhood Hits	808	Target Neighborhood Hits	526	Shared Neighborhood Hits	311
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TR11B_MOUSE
θ value	0.0431538 (rank : 363)	NC score	0.099429 (rank : 601)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

ADA19_HUMAN
θ value	0.0563607 (rank : 364)	NC score	0.160785 (rank : 437)
Query Neighborhood Hits	808	Target Neighborhood Hits	381	Shared Neighborhood Hits	203
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

EMSY_HUMAN
θ value	0.0563607 (rank : 365)	NC score	0.080250 (rank : 665)
Query Neighborhood Hits	808	Target Neighborhood Hits	296	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

LCE3A_HUMAN
θ value	0.0563607 (rank : 366)	NC score	0.330042 (rank : 256)
Query Neighborhood Hits	808	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LYAM2_MOUSE
θ value	0.0563607 (rank : 367)	NC score	0.284196 (rank : 276)
Query Neighborhood Hits	808	Target Neighborhood Hits	420	Shared Neighborhood Hits	273
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MEP1B_HUMAN
θ value	0.0563607 (rank : 368)	NC score	0.112683 (rank : 554)
Query Neighborhood Hits	808	Target Neighborhood Hits	98	Shared Neighborhood Hits	72
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

PGCA_HUMAN
θ value	0.0563607 (rank : 369)	NC score	0.184373 (rank : 379)
Query Neighborhood Hits	808	Target Neighborhood Hits	821	Shared Neighborhood Hits	223
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

SPR2B_MOUSE
θ value	0.0563607 (rank : 370)	NC score	0.126376 (rank : 512)
Query Neighborhood Hits	808	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

TR10C_HUMAN
θ value	0.0563607 (rank : 371)	NC score	0.089927 (rank : 637)
Query Neighborhood Hits	808	Target Neighborhood Hits	105	Shared Neighborhood Hits	59
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

WISP1_MOUSE
θ value	0.0563607 (rank : 372)	NC score	0.174840 (rank : 406)
Query Neighborhood Hits	808	Target Neighborhood Hits	123	Shared Neighborhood Hits	81
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WWP1_HUMAN
θ value	0.0563607 (rank : 373)	NC score	0.016030 (rank : 1045)
Query Neighborhood Hits	808	Target Neighborhood Hits	262	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

ARID2_HUMAN
θ value	0.0736092 (rank : 374)	NC score	0.062479 (rank : 797)
Query Neighborhood Hits	808	Target Neighborhood Hits	302	Shared Neighborhood Hits	44
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

CEL_HUMAN
θ value	0.0736092 (rank : 375)	NC score	0.042488 (rank : 963)
Query Neighborhood Hits	808	Target Neighborhood Hits	896	Shared Neighborhood Hits	69
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

COFA1_MOUSE
θ value	0.0736092 (rank : 376)	NC score	0.045028 (rank : 955)
Query Neighborhood Hits	808	Target Neighborhood Hits	305	Shared Neighborhood Hits	40
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

CRDL1_MOUSE
θ value	0.0736092 (rank : 377)	NC score	0.221924 (rank : 319)
Query Neighborhood Hits	808	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

FA9_HUMAN
θ value	0.0736092 (rank : 378)	NC score	0.197495 (rank : 359)
Query Neighborhood Hits	808	Target Neighborhood Hits	421	Shared Neighborhood Hits	232
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FINC_HUMAN
θ value	0.0736092 (rank : 379)	NC score	0.099615 (rank : 600)
Query Neighborhood Hits	808	Target Neighborhood Hits	302	Shared Neighborhood Hits	82
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

MATN3_HUMAN
θ value	0.0736092 (rank : 380)	NC score	0.411862 (rank : 185)
Query Neighborhood Hits	808	Target Neighborhood Hits	268	Shared Neighborhood Hits	190
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

NET2_MOUSE
θ value	0.0736092 (rank : 381)	NC score	0.252945 (rank : 291)
Query Neighborhood Hits	808	Target Neighborhood Hits	193	Shared Neighborhood Hits	154
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NRX2A_HUMAN
θ value	0.0736092 (rank : 382)	NC score	0.188338 (rank : 373)
Query Neighborhood Hits	808	Target Neighborhood Hits	614	Shared Neighborhood Hits	157
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

PROZ_HUMAN
θ value	0.0736092 (rank : 383)	NC score	0.359542 (rank : 226)
Query Neighborhood Hits	808	Target Neighborhood Hits	422	Shared Neighborhood Hits	248
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

RTP3_MOUSE
θ value	0.0736092 (rank : 384)	NC score	0.082690 (rank : 655)
Query Neighborhood Hits	808	Target Neighborhood Hits	374	Shared Neighborhood Hits	52
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

ATS13_HUMAN
θ value	0.0961366 (rank : 385)	NC score	0.064877 (rank : 770)
Query Neighborhood Hits	808	Target Neighborhood Hits	238	Shared Neighborhood Hits	82
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

CNTP3_HUMAN
θ value	0.0961366 (rank : 386)	NC score	0.180331 (rank : 394)
Query Neighborhood Hits	808	Target Neighborhood Hits	195	Shared Neighborhood Hits	138
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

ERBB2_MOUSE
θ value	0.0961366 (rank : 387)	NC score	0.021800 (rank : 1027)
Query Neighborhood Hits	808	Target Neighborhood Hits	918	Shared Neighborhood Hits	89
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ITB4_HUMAN
θ value	0.0961366 (rank : 388)	NC score	0.318293 (rank : 266)
Query Neighborhood Hits	808	Target Neighborhood Hits	458	Shared Neighborhood Hits	269
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

LCE1E_HUMAN
θ value	0.0961366 (rank : 389)	NC score	0.356519 (rank : 230)
Query Neighborhood Hits	808	Target Neighborhood Hits	53	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	0.0961366 (rank : 390)	NC score	0.359334 (rank : 227)
Query Neighborhood Hits	808	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

MFGM_HUMAN
θ value	0.0961366 (rank : 391)	NC score	0.190437 (rank : 367)
Query Neighborhood Hits	808	Target Neighborhood Hits	150	Shared Neighborhood Hits	126
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

SPR2D_MOUSE
θ value	0.0961366 (rank : 392)	NC score	0.163996 (rank : 431)
Query Neighborhood Hits	808	Target Neighborhood Hits	61	Shared Neighborhood Hits	35
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2H_MOUSE
θ value	0.0961366 (rank : 393)	NC score	0.133007 (rank : 490)
Query Neighborhood Hits	808	Target Neighborhood Hits	82	Shared Neighborhood Hits	42
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2I_MOUSE
θ value	0.0961366 (rank : 394)	NC score	0.143248 (rank : 467)
Query Neighborhood Hits	808	Target Neighborhood Hits	45	Shared Neighborhood Hits	26
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

TARSH_HUMAN
θ value	0.0961366 (rank : 395)	NC score	0.131169 (rank : 497)
Query Neighborhood Hits	808	Target Neighborhood Hits	768	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TRI42_HUMAN
θ value	0.0961366 (rank : 396)	NC score	0.052438 (rank : 903)
Query Neighborhood Hits	808	Target Neighborhood Hits	283	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TS1R2_MOUSE
θ value	0.0961366 (rank : 397)	NC score	0.011863 (rank : 1066)
Query Neighborhood Hits	808	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

ADA33_MOUSE
θ value	0.125558 (rank : 398)	NC score	0.149944 (rank : 458)
Query Neighborhood Hits	808	Target Neighborhood Hits	231	Shared Neighborhood Hits	180
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

AL2SA_HUMAN
θ value	0.125558 (rank : 399)	NC score	0.035674 (rank : 985)
Query Neighborhood Hits	808	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	Q53TS8, Q8NCN6, Q96LN4	Gene names	ALS2CR11
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein.

CRDL1_HUMAN
θ value	0.125558 (rank : 400)	NC score	0.203399 (rank : 348)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

ELTD1_MOUSE
θ value	0.125558 (rank : 401)	NC score	0.353321 (rank : 233)
Query Neighborhood Hits	808	Target Neighborhood Hits	288	Shared Neighborhood Hits	191
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

FA7_MOUSE
θ value	0.125558 (rank : 402)	NC score	0.157979 (rank : 446)
Query Neighborhood Hits	808	Target Neighborhood Hits	374	Shared Neighborhood Hits	194
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

GAS6_HUMAN
θ value	0.125558 (rank : 403)	NC score	0.496753 (rank : 125)
Query Neighborhood Hits	808	Target Neighborhood Hits	348	Shared Neighborhood Hits	277
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

MKS3_MOUSE
θ value	0.125558 (rank : 404)	NC score	0.132818 (rank : 492)
Query Neighborhood Hits	808	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

PCLO_HUMAN
θ value	0.125558 (rank : 405)	NC score	0.069497 (rank : 736)
Query Neighborhood Hits	808	Target Neighborhood Hits	2046	Shared Neighborhood Hits	142
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SEM5A_HUMAN
θ value	0.125558 (rank : 406)	NC score	0.065394 (rank : 764)
Query Neighborhood Hits	808	Target Neighborhood Hits	177	Shared Neighborhood Hits	69
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SPR2E_MOUSE
θ value	0.125558 (rank : 407)	NC score	0.132932 (rank : 491)
Query Neighborhood Hits	808	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

TIE1_HUMAN
θ value	0.125558 (rank : 408)	NC score	0.156244 (rank : 449)
Query Neighborhood Hits	808	Target Neighborhood Hits	1241	Shared Neighborhood Hits	303
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TNR8_MOUSE
θ value	0.125558 (rank : 409)	NC score	0.174813 (rank : 408)
Query Neighborhood Hits	808	Target Neighborhood Hits	208	Shared Neighborhood Hits	110
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

ADA21_MOUSE
θ value	0.163984 (rank : 410)	NC score	0.130216 (rank : 500)
Query Neighborhood Hits	808	Target Neighborhood Hits	172	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

CNTP4_MOUSE
θ value	0.163984 (rank : 411)	NC score	0.186874 (rank : 376)
Query Neighborhood Hits	808	Target Neighborhood Hits	193	Shared Neighborhood Hits	147
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

DGKK_HUMAN
θ value	0.163984 (rank : 412)	NC score	0.061025 (rank : 815)
Query Neighborhood Hits	808	Target Neighborhood Hits	378	Shared Neighborhood Hits	60
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

FA7_HUMAN
θ value	0.163984 (rank : 413)	NC score	0.184357 (rank : 380)
Query Neighborhood Hits	808	Target Neighborhood Hits	404	Shared Neighborhood Hits	219
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

GON4L_MOUSE
θ value	0.163984 (rank : 414)	NC score	0.040963 (rank : 970)
Query Neighborhood Hits	808	Target Neighborhood Hits	455	Shared Neighborhood Hits	52
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

IGF1R_HUMAN
θ value	0.163984 (rank : 415)	NC score	0.042818 (rank : 962)
Query Neighborhood Hits	808	Target Neighborhood Hits	977	Shared Neighborhood Hits	155
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

ITB1_HUMAN
θ value	0.163984 (rank : 416)	NC score	0.331643 (rank : 254)
Query Neighborhood Hits	808	Target Neighborhood Hits	298	Shared Neighborhood Hits	253
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KR122_HUMAN
θ value	0.163984 (rank : 417)	NC score	0.203875 (rank : 347)
Query Neighborhood Hits	808	Target Neighborhood Hits	97	Shared Neighborhood Hits	75
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

MATN4_HUMAN
θ value	0.163984 (rank : 418)	NC score	0.416496 (rank : 181)
Query Neighborhood Hits	808	Target Neighborhood Hits	287	Shared Neighborhood Hits	211
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MMRN1_HUMAN
θ value	0.163984 (rank : 419)	NC score	0.164975 (rank : 430)
Query Neighborhood Hits	808	Target Neighborhood Hits	636	Shared Neighborhood Hits	155
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

NID1_MOUSE
θ value	0.163984 (rank : 420)	NC score	0.501011 (rank : 119)
Query Neighborhood Hits	808	Target Neighborhood Hits	335	Shared Neighborhood Hits	252
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

PTPRM_MOUSE
θ value	0.163984 (rank : 421)	NC score	0.070629 (rank : 728)
Query Neighborhood Hits	808	Target Neighborhood Hits	238	Shared Neighborhood Hits	55
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

SYNPO_HUMAN
θ value	0.163984 (rank : 422)	NC score	0.048296 (rank : 945)
Query Neighborhood Hits	808	Target Neighborhood Hits	281	Shared Neighborhood Hits	47
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TITIN_HUMAN
θ value	0.163984 (rank : 423)	NC score	0.043050 (rank : 960)
Query Neighborhood Hits	808	Target Neighborhood Hits	2923	Shared Neighborhood Hits	198
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TNR7_HUMAN
θ value	0.163984 (rank : 424)	NC score	0.138301 (rank : 474)
Query Neighborhood Hits	808	Target Neighborhood Hits	120	Shared Neighborhood Hits	91
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TR10A_HUMAN
θ value	0.163984 (rank : 425)	NC score	0.079968 (rank : 668)
Query Neighborhood Hits	808	Target Neighborhood Hits	82	Shared Neighborhood Hits	50
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

ADA12_HUMAN
θ value	0.21417 (rank : 426)	NC score	0.139430 (rank : 470)
Query Neighborhood Hits	808	Target Neighborhood Hits	224	Shared Neighborhood Hits	158
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

BAI3_HUMAN
θ value	0.21417 (rank : 427)	NC score	0.096923 (rank : 610)
Query Neighborhood Hits	808	Target Neighborhood Hits	246	Shared Neighborhood Hits	82
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CFC1_HUMAN
θ value	0.21417 (rank : 428)	NC score	0.289206 (rank : 273)
Query Neighborhood Hits	808	Target Neighborhood Hits	148	Shared Neighborhood Hits	127
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

HGFA_HUMAN
θ value	0.21417 (rank : 429)	NC score	0.180614 (rank : 393)
Query Neighborhood Hits	808	Target Neighborhood Hits	436	Shared Neighborhood Hits	212
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

IBRD2_HUMAN
θ value	0.21417 (rank : 430)	NC score	0.020769 (rank : 1031)
Query Neighborhood Hits	808	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

KIF17_MOUSE
θ value	0.21417 (rank : 431)	NC score	0.002796 (rank : 1114)
Query Neighborhood Hits	808	Target Neighborhood Hits	452	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

KR261_HUMAN
θ value	0.21417 (rank : 432)	NC score	0.160921 (rank : 436)
Query Neighborhood Hits	808	Target Neighborhood Hits	65	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

KR410_HUMAN
θ value	0.21417 (rank : 433)	NC score	0.357476 (rank : 229)
Query Neighborhood Hits	808	Target Neighborhood Hits	156	Shared Neighborhood Hits	140
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

NET2_HUMAN
θ value	0.21417 (rank : 434)	NC score	0.250958 (rank : 294)
Query Neighborhood Hits	808	Target Neighborhood Hits	194	Shared Neighborhood Hits	149
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET4_HUMAN
θ value	0.21417 (rank : 435)	NC score	0.253368 (rank : 290)
Query Neighborhood Hits	808	Target Neighborhood Hits	191	Shared Neighborhood Hits	156
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

PAPPA_MOUSE
θ value	0.21417 (rank : 436)	NC score	0.122322 (rank : 529)
Query Neighborhood Hits	808	Target Neighborhood Hits	153	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PCSK9_HUMAN
θ value	0.21417 (rank : 437)	NC score	0.028612 (rank : 1002)
Query Neighborhood Hits	808	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NBP7, Q5PSM5	Gene names	PCSK9, NARC1
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 9 precursor (EC 3.4.21.-) (Proprotein convertase PC9) (Subtilisin/kexin-like protease PC9) (Neural apoptosis-regulated convertase 1) (NARC-1).

SPR2F_MOUSE
θ value	0.21417 (rank : 438)	NC score	0.122813 (rank : 528)
Query Neighborhood Hits	808	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

TACC3_HUMAN
θ value	0.21417 (rank : 439)	NC score	0.022765 (rank : 1025)
Query Neighborhood Hits	808	Target Neighborhood Hits	779	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TENR_MOUSE
θ value	0.21417 (rank : 440)	NC score	0.339438 (rank : 250)
Query Neighborhood Hits	808	Target Neighborhood Hits	531	Shared Neighborhood Hits	318
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TM108_MOUSE
θ value	0.21417 (rank : 441)	NC score	0.094378 (rank : 622)
Query Neighborhood Hits	808	Target Neighborhood Hits	336	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMPS7_MOUSE
θ value	0.21417 (rank : 442)	NC score	0.083281 (rank : 652)
Query Neighborhood Hits	808	Target Neighborhood Hits	275	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TNR11_MOUSE
θ value	0.21417 (rank : 443)	NC score	0.106791 (rank : 575)
Query Neighborhood Hits	808	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR1A_MOUSE
θ value	0.21417 (rank : 444)	NC score	0.111846 (rank : 556)
Query Neighborhood Hits	808	Target Neighborhood Hits	131	Shared Neighborhood Hits	72
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR21_HUMAN
θ value	0.21417 (rank : 445)	NC score	0.113364 (rank : 550)
Query Neighborhood Hits	808	Target Neighborhood Hits	90	Shared Neighborhood Hits	59
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

ADA15_HUMAN
θ value	0.279714 (rank : 446)	NC score	0.170410 (rank : 418)
Query Neighborhood Hits	808	Target Neighborhood Hits	288	Shared Neighborhood Hits	216
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA25_MOUSE
θ value	0.279714 (rank : 447)	NC score	0.127607 (rank : 508)
Query Neighborhood Hits	808	Target Neighborhood Hits	213	Shared Neighborhood Hits	164
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA28_MOUSE
θ value	0.279714 (rank : 448)	NC score	0.137853 (rank : 477)
Query Neighborhood Hits	808	Target Neighborhood Hits	241	Shared Neighborhood Hits	184
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

CNTP4_HUMAN
θ value	0.279714 (rank : 449)	NC score	0.182103 (rank : 392)
Query Neighborhood Hits	808	Target Neighborhood Hits	187	Shared Neighborhood Hits	131
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CO1A1_MOUSE
θ value	0.279714 (rank : 450)	NC score	0.072274 (rank : 713)
Query Neighborhood Hits	808	Target Neighborhood Hits	457	Shared Neighborhood Hits	86
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

IBRD2_MOUSE
θ value	0.279714 (rank : 451)	NC score	0.023090 (rank : 1024)
Query Neighborhood Hits	808	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

LRP10_MOUSE
θ value	0.279714 (rank : 452)	NC score	0.172714 (rank : 411)
Query Neighborhood Hits	808	Target Neighborhood Hits	169	Shared Neighborhood Hits	99
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

ODFP_MOUSE
θ value	0.279714 (rank : 453)	NC score	0.080927 (rank : 662)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

SEPP1_MOUSE
θ value	0.279714 (rank : 454)	NC score	0.046851 (rank : 947)
Query Neighborhood Hits	808	Target Neighborhood Hits	35	Shared Neighborhood Hits	28
SwissProt Accessions	P70274, Q9Z2T7	Gene names	Sepp1, Selp
Domain Architecture
Description	Selenoprotein P precursor (SeP) (Plasma selenoprotein P).

TLL2_HUMAN
θ value	0.279714 (rank : 455)	NC score	0.205633 (rank : 344)
Query Neighborhood Hits	808	Target Neighborhood Hits	241	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TNR7_MOUSE
θ value	0.279714 (rank : 456)	NC score	0.118339 (rank : 539)
Query Neighborhood Hits	808	Target Neighborhood Hits	112	Shared Neighborhood Hits	77
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

UBP28_MOUSE
θ value	0.279714 (rank : 457)	NC score	0.013076 (rank : 1059)
Query Neighborhood Hits	808	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

WFDC3_HUMAN
θ value	0.279714 (rank : 458)	NC score	0.231388 (rank : 314)
Query Neighborhood Hits	808	Target Neighborhood Hits	138	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WISP3_HUMAN
θ value	0.279714 (rank : 459)	NC score	0.111696 (rank : 557)
Query Neighborhood Hits	808	Target Neighborhood Hits	87	Shared Neighborhood Hits	49
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

ADA30_HUMAN
θ value	0.365318 (rank : 460)	NC score	0.138419 (rank : 473)
Query Neighborhood Hits	808	Target Neighborhood Hits	391	Shared Neighborhood Hits	154
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ATS16_HUMAN
θ value	0.365318 (rank : 461)	NC score	0.071950 (rank : 714)
Query Neighborhood Hits	808	Target Neighborhood Hits	208	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS1_MOUSE
θ value	0.365318 (rank : 462)	NC score	0.066348 (rank : 754)
Query Neighborhood Hits	808	Target Neighborhood Hits	158	Shared Neighborhood Hits	89
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

BAI3_MOUSE
θ value	0.365318 (rank : 463)	NC score	0.099903 (rank : 598)
Query Neighborhood Hits	808	Target Neighborhood Hits	250	Shared Neighborhood Hits	86
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CO5A2_HUMAN
θ value	0.365318 (rank : 464)	NC score	0.063699 (rank : 782)
Query Neighborhood Hits	808	Target Neighborhood Hits	760	Shared Neighborhood Hits	101
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

DGKD_HUMAN
θ value	0.365318 (rank : 465)	NC score	0.015357 (rank : 1048)
Query Neighborhood Hits	808	Target Neighborhood Hits	231	Shared Neighborhood Hits	15
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

ERN2_HUMAN
θ value	0.365318 (rank : 466)	NC score	-0.005766 (rank : 1129)
Query Neighborhood Hits	808	Target Neighborhood Hits	844	Shared Neighborhood Hits	31
SwissProt Accessions	Q76MJ5, Q6ZNC0	Gene names	ERN2, IRE2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (hIRE2p) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

IGF1R_MOUSE
θ value	0.365318 (rank : 467)	NC score	0.044402 (rank : 957)
Query Neighborhood Hits	808	Target Neighborhood Hits	973	Shared Neighborhood Hits	151
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSRR_MOUSE
θ value	0.365318 (rank : 468)	NC score	0.050284 (rank : 933)
Query Neighborhood Hits	808	Target Neighborhood Hits	961	Shared Neighborhood Hits	152
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

ITB8_HUMAN
θ value	0.365318 (rank : 469)	NC score	0.286097 (rank : 275)
Query Neighborhood Hits	808	Target Neighborhood Hits	280	Shared Neighborhood Hits	230
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

MT1_MOUSE
θ value	0.365318 (rank : 470)	NC score	0.144329 (rank : 465)
Query Neighborhood Hits	808	Target Neighborhood Hits	72	Shared Neighborhood Hits	63
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

NET4_MOUSE
θ value	0.365318 (rank : 471)	NC score	0.248831 (rank : 298)
Query Neighborhood Hits	808	Target Neighborhood Hits	180	Shared Neighborhood Hits	154
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NRX3A_HUMAN
θ value	0.365318 (rank : 472)	NC score	0.184973 (rank : 378)
Query Neighborhood Hits	808	Target Neighborhood Hits	164	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PG12A_MOUSE
θ value	0.365318 (rank : 473)	NC score	0.033988 (rank : 987)
Query Neighborhood Hits	808	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPR2, Q3TQC4, Q9CQR3, Q9CTL1, Q9D7L3, Q9EPR1	Gene names	Pla2g12a, Pla2g12
Domain Architecture
Description	Group XIIA secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GXII) (GXII sPLA2).

SEM5B_HUMAN
θ value	0.365318 (rank : 474)	NC score	0.062218 (rank : 802)
Query Neighborhood Hits	808	Target Neighborhood Hits	178	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

TRAF7_MOUSE
θ value	0.365318 (rank : 475)	NC score	0.000328 (rank : 1120)
Query Neighborhood Hits	808	Target Neighborhood Hits	470	Shared Neighborhood Hits	10
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

ZN274_HUMAN
θ value	0.365318 (rank : 476)	NC score	-0.013930 (rank : 1133)
Query Neighborhood Hits	808	Target Neighborhood Hits	770	Shared Neighborhood Hits	10
SwissProt Accessions	Q96GC6, Q8WY37, Q8WY38, Q92969, Q9UII0, Q9UII1	Gene names	ZNF274
Domain Architecture
Description	Zinc finger protein 274 (Zinc finger protein HFB101) (Zinc finger protein zfp2) (Zf2).

ZNFX1_MOUSE
θ value	0.365318 (rank : 477)	NC score	0.205488 (rank : 345)
Query Neighborhood Hits	808	Target Neighborhood Hits	407	Shared Neighborhood Hits	169
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ADA22_MOUSE
θ value	0.47712 (rank : 478)	NC score	0.139862 (rank : 469)
Query Neighborhood Hits	808	Target Neighborhood Hits	225	Shared Neighborhood Hits	176
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA32_MOUSE
θ value	0.47712 (rank : 479)	NC score	0.131339 (rank : 496)
Query Neighborhood Hits	808	Target Neighborhood Hits	219	Shared Neighborhood Hits	179
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

BMP1_HUMAN
θ value	0.47712 (rank : 480)	NC score	0.211164 (rank : 333)
Query Neighborhood Hits	808	Target Neighborhood Hits	233	Shared Neighborhood Hits	159
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	0.47712 (rank : 481)	NC score	0.212432 (rank : 330)
Query Neighborhood Hits	808	Target Neighborhood Hits	236	Shared Neighborhood Hits	160
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CR1_HUMAN
θ value	0.47712 (rank : 482)	NC score	0.058285 (rank : 848)
Query Neighborhood Hits	808	Target Neighborhood Hits	108	Shared Neighborhood Hits	40
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

FURIN_MOUSE
θ value	0.47712 (rank : 483)	NC score	0.063901 (rank : 778)
Query Neighborhood Hits	808	Target Neighborhood Hits	49	Shared Neighborhood Hits	26
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

IMPG1_MOUSE
θ value	0.47712 (rank : 484)	NC score	0.043952 (rank : 958)
Query Neighborhood Hits	808	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).

LHX6_MOUSE
θ value	0.47712 (rank : 485)	NC score	-0.002050 (rank : 1124)
Query Neighborhood Hits	808	Target Neighborhood Hits	399	Shared Neighborhood Hits	6
SwissProt Accessions	O88706	Gene names	Lhx6
Domain Architecture
Description	LIM/homeobox protein Lhx6.

MKS3_HUMAN
θ value	0.47712 (rank : 486)	NC score	0.137268 (rank : 478)
Query Neighborhood Hits	808	Target Neighborhood Hits	79	Shared Neighborhood Hits	68
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

PF21A_HUMAN
θ value	0.47712 (rank : 487)	NC score	0.032021 (rank : 993)
Query Neighborhood Hits	808	Target Neighborhood Hits	303	Shared Neighborhood Hits	32
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PG12A_HUMAN
θ value	0.47712 (rank : 488)	NC score	0.037985 (rank : 978)
Query Neighborhood Hits	808	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZM1, Q9BZ89	Gene names	PLA2G12A, PLA2G12
Domain Architecture
Description	Group XIIA secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GXII) (GXII sPLA2).

RELN_HUMAN
θ value	0.47712 (rank : 489)	NC score	0.169511 (rank : 420)
Query Neighborhood Hits	808	Target Neighborhood Hits	233	Shared Neighborhood Hits	176
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

SPRR3_MOUSE
θ value	0.47712 (rank : 490)	NC score	0.082942 (rank : 653)
Query Neighborhood Hits	808	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

TENN_HUMAN
θ value	0.47712 (rank : 491)	NC score	0.264547 (rank : 284)
Query Neighborhood Hits	808	Target Neighborhood Hits	453	Shared Neighborhood Hits	271
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TIE2_HUMAN
θ value	0.47712 (rank : 492)	NC score	0.135070 (rank : 485)
Query Neighborhood Hits	808	Target Neighborhood Hits	1192	Shared Neighborhood Hits	280
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

VEGFC_MOUSE
θ value	0.47712 (rank : 493)	NC score	0.146197 (rank : 462)
Query Neighborhood Hits	808	Target Neighborhood Hits	119	Shared Neighborhood Hits	97
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

WISP1_HUMAN
θ value	0.47712 (rank : 494)	NC score	0.160313 (rank : 438)
Query Neighborhood Hits	808	Target Neighborhood Hits	121	Shared Neighborhood Hits	81
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

ALK1_HUMAN
θ value	0.62314 (rank : 495)	NC score	0.045147 (rank : 953)
Query Neighborhood Hits	808	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	P03973, P07757	Gene names	SLPI, WAP4, WFDC4
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (HUSI-1) (Seminal proteinase inhibitor) (Secretory leukocyte protease inhibitor) (BLPI) (Mucus proteinase inhibitor) (MPI) (WAP four-disulfide core domain protein 4) (Protease inhibitor WAP4).

CU063_MOUSE
θ value	0.62314 (rank : 496)	NC score	0.019360 (rank : 1035)
Query Neighborhood Hits	808	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P58659	Gene names
Domain Architecture
Description	Protein C21orf63 homolog precursor.

DGKH_HUMAN
θ value	0.62314 (rank : 497)	NC score	0.016163 (rank : 1044)
Query Neighborhood Hits	808	Target Neighborhood Hits	255	Shared Neighborhood Hits	19
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

EZH1_HUMAN
θ value	0.62314 (rank : 498)	NC score	0.045559 (rank : 952)
Query Neighborhood Hits	808	Target Neighborhood Hits	121	Shared Neighborhood Hits	51
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	0.62314 (rank : 499)	NC score	0.049337 (rank : 942)
Query Neighborhood Hits	808	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

KAISO_HUMAN
θ value	0.62314 (rank : 500)	NC score	-0.008024 (rank : 1130)
Query Neighborhood Hits	808	Target Neighborhood Hits	840	Shared Neighborhood Hits	24
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

KR171_HUMAN
θ value	0.62314 (rank : 501)	NC score	0.432458 (rank : 157)
Query Neighborhood Hits	808	Target Neighborhood Hits	144	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

LCE2B_HUMAN
θ value	0.62314 (rank : 502)	NC score	0.188278 (rank : 374)
Query Neighborhood Hits	808	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

MT1G_HUMAN
θ value	0.62314 (rank : 503)	NC score	0.113870 (rank : 546)
Query Neighborhood Hits	808	Target Neighborhood Hits	63	Shared Neighborhood Hits	55
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

PGH2_HUMAN
θ value	0.62314 (rank : 504)	NC score	0.136086 (rank : 481)
Query Neighborhood Hits	808	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PROC_MOUSE
θ value	0.62314 (rank : 505)	NC score	0.196042 (rank : 361)
Query Neighborhood Hits	808	Target Neighborhood Hits	426	Shared Neighborhood Hits	244
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

SEM5A_MOUSE
θ value	0.62314 (rank : 506)	NC score	0.053959 (rank : 880)
Query Neighborhood Hits	808	Target Neighborhood Hits	162	Shared Neighborhood Hits	51
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SPR2G_MOUSE
θ value	0.62314 (rank : 507)	NC score	0.130764 (rank : 499)
Query Neighborhood Hits	808	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

TARA_HUMAN
θ value	0.62314 (rank : 508)	NC score	0.061532 (rank : 809)
Query Neighborhood Hits	808	Target Neighborhood Hits	1626	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TNR3_HUMAN
θ value	0.62314 (rank : 509)	NC score	0.104830 (rank : 580)
Query Neighborhood Hits	808	Target Neighborhood Hits	145	Shared Neighborhood Hits	73
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

ADA20_HUMAN
θ value	0.813845 (rank : 510)	NC score	0.101263 (rank : 596)
Query Neighborhood Hits	808	Target Neighborhood Hits	143	Shared Neighborhood Hits	106
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

AT2A3_HUMAN
θ value	0.813845 (rank : 511)	NC score	0.005997 (rank : 1096)
Query Neighborhood Hits	808	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q93084, O60900, O60901, O75501, O75502, Q16115, Q8TEX5, Q8TEX6	Gene names	ATP2A3
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8) (Calcium pump 3) (SERCA3) (SR Ca(2+)-ATPase 3).

AT2A3_MOUSE
θ value	0.813845 (rank : 512)	NC score	0.004961 (rank : 1102)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q64518, O70625, Q64517	Gene names	Atp2a3
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8) (Calcium pump 3) (SERCA3) (SR Ca(2+)-ATPase 3).

ATS8_HUMAN
θ value	0.813845 (rank : 513)	NC score	0.062083 (rank : 804)
Query Neighborhood Hits	808	Target Neighborhood Hits	145	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

EGFR_MOUSE
θ value	0.813845 (rank : 514)	NC score	0.021367 (rank : 1029)
Query Neighborhood Hits	808	Target Neighborhood Hits	927	Shared Neighborhood Hits	107
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

FA10_HUMAN
θ value	0.813845 (rank : 515)	NC score	0.206139 (rank : 343)
Query Neighborhood Hits	808	Target Neighborhood Hits	431	Shared Neighborhood Hits	240
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

LCE2D_HUMAN
θ value	0.813845 (rank : 516)	NC score	0.199599 (rank : 354)
Query Neighborhood Hits	808	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE4A_HUMAN
θ value	0.813845 (rank : 517)	NC score	0.244772 (rank : 300)
Query Neighborhood Hits	808	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LY6H_HUMAN
θ value	0.813845 (rank : 518)	NC score	0.029627 (rank : 1001)
Query Neighborhood Hits	808	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	O94772	Gene names	LY6H
Domain Architecture
Description	Lymphocyte antigen Ly-6H precursor.

LYAM1_MOUSE
θ value	0.813845 (rank : 519)	NC score	0.232339 (rank : 311)
Query Neighborhood Hits	808	Target Neighborhood Hits	332	Shared Neighborhood Hits	202
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MATN3_MOUSE
θ value	0.813845 (rank : 520)	NC score	0.407672 (rank : 188)
Query Neighborhood Hits	808	Target Neighborhood Hits	261	Shared Neighborhood Hits	193
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

NGL1_HUMAN
θ value	0.813845 (rank : 521)	NC score	0.018447 (rank : 1038)
Query Neighborhood Hits	808	Target Neighborhood Hits	511	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

PRG4_MOUSE
θ value	0.813845 (rank : 522)	NC score	0.105802 (rank : 577)
Query Neighborhood Hits	808	Target Neighborhood Hits	624	Shared Neighborhood Hits	109
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RP1_HUMAN
θ value	0.813845 (rank : 523)	NC score	0.012431 (rank : 1062)
Query Neighborhood Hits	808	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	P56715	Gene names	RP1, ORP1
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein) (Retinitis pigmentosa 1 protein).

TAF9B_HUMAN
θ value	0.813845 (rank : 524)	NC score	0.031502 (rank : 995)
Query Neighborhood Hits	808	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HBM6, Q9Y2S3	Gene names	TAF9B, TAF9L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 9B (Transcription initiation factor TFIID subunit 9-like protein) (Transcription- associated factor TAFII31L) (Neuronal cell death-related protein 7) (DN-7).

THYG_HUMAN
θ value	0.813845 (rank : 525)	NC score	0.051592 (rank : 918)
Query Neighborhood Hits	808	Target Neighborhood Hits	154	Shared Neighborhood Hits	60
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

ADA23_HUMAN
θ value	1.06291 (rank : 526)	NC score	0.165807 (rank : 427)
Query Neighborhood Hits	808	Target Neighborhood Hits	235	Shared Neighborhood Hits	194
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADAM8_HUMAN
θ value	1.06291 (rank : 527)	NC score	0.183530 (rank : 386)
Query Neighborhood Hits	808	Target Neighborhood Hits	327	Shared Neighborhood Hits	241
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADDB_MOUSE
θ value	1.06291 (rank : 528)	NC score	0.023633 (rank : 1021)
Query Neighborhood Hits	808	Target Neighborhood Hits	574	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ALMS1_MOUSE
θ value	1.06291 (rank : 529)	NC score	0.041520 (rank : 966)
Query Neighborhood Hits	808	Target Neighborhood Hits	181	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

AQR_HUMAN
θ value	1.06291 (rank : 530)	NC score	0.029959 (rank : 998)
Query Neighborhood Hits	808	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

ATL1_MOUSE
θ value	1.06291 (rank : 531)	NC score	0.038593 (rank : 976)
Query Neighborhood Hits	808	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

BRD1_HUMAN
θ value	1.06291 (rank : 532)	NC score	0.007340 (rank : 1089)
Query Neighborhood Hits	808	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

CABYR_HUMAN
θ value	1.06291 (rank : 533)	NC score	0.029730 (rank : 999)
Query Neighborhood Hits	808	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

CFAI_HUMAN
θ value	1.06291 (rank : 534)	NC score	0.075621 (rank : 698)
Query Neighborhood Hits	808	Target Neighborhood Hits	289	Shared Neighborhood Hits	75
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CNTP2_HUMAN
θ value	1.06291 (rank : 535)	NC score	0.189802 (rank : 370)
Query Neighborhood Hits	808	Target Neighborhood Hits	199	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	1.06291 (rank : 536)	NC score	0.190049 (rank : 369)
Query Neighborhood Hits	808	Target Neighborhood Hits	194	Shared Neighborhood Hits	147
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CTGF_HUMAN
θ value	1.06291 (rank : 537)	NC score	0.169860 (rank : 419)
Query Neighborhood Hits	808	Target Neighborhood Hits	128	Shared Neighborhood Hits	88
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

EPHB6_HUMAN
θ value	1.06291 (rank : 538)	NC score	0.024974 (rank : 1012)
Query Neighborhood Hits	808	Target Neighborhood Hits	912	Shared Neighborhood Hits	112
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

HYAL3_HUMAN
θ value	1.06291 (rank : 539)	NC score	0.040087 (rank : 973)
Query Neighborhood Hits	808	Target Neighborhood Hits	45	Shared Neighborhood Hits	36
SwissProt Accessions	O43820, O60540, Q8NFK2, Q8NFK3, Q8NFK4, Q96E56, Q9BRW9	Gene names	HYAL3, LUCA3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3) (LUCA-3).

IMPG1_HUMAN
θ value	1.06291 (rank : 540)	NC score	0.063725 (rank : 781)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	29
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

INSRR_HUMAN
θ value	1.06291 (rank : 541)	NC score	0.052102 (rank : 907)
Query Neighborhood Hits	808	Target Neighborhood Hits	950	Shared Neighborhood Hits	137
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

ITB3_MOUSE
θ value	1.06291 (rank : 542)	NC score	0.333110 (rank : 253)
Query Neighborhood Hits	808	Target Neighborhood Hits	319	Shared Neighborhood Hits	266
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

LCE1C_HUMAN
θ value	1.06291 (rank : 543)	NC score	0.345545 (rank : 244)
Query Neighborhood Hits	808	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE2C_HUMAN
θ value	1.06291 (rank : 544)	NC score	0.214783 (rank : 326)
Query Neighborhood Hits	808	Target Neighborhood Hits	53	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LEUK_HUMAN
θ value	1.06291 (rank : 545)	NC score	0.113714 (rank : 547)
Query Neighborhood Hits	808	Target Neighborhood Hits	213	Shared Neighborhood Hits	43
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LR37B_HUMAN
θ value	1.06291 (rank : 546)	NC score	0.063567 (rank : 783)
Query Neighborhood Hits	808	Target Neighborhood Hits	392	Shared Neighborhood Hits	55
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MAP1A_HUMAN
θ value	1.06291 (rank : 547)	NC score	0.028599 (rank : 1003)
Query Neighborhood Hits	808	Target Neighborhood Hits	1626	Shared Neighborhood Hits	74
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MEP1A_HUMAN
θ value	1.06291 (rank : 548)	NC score	0.183838 (rank : 384)
Query Neighborhood Hits	808	Target Neighborhood Hits	162	Shared Neighborhood Hits	141
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	1.06291 (rank : 549)	NC score	0.190558 (rank : 366)
Query Neighborhood Hits	808	Target Neighborhood Hits	166	Shared Neighborhood Hits	146
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MT2_MOUSE
θ value	1.06291 (rank : 550)	NC score	0.135962 (rank : 482)
Query Neighborhood Hits	808	Target Neighborhood Hits	81	Shared Neighborhood Hits	70
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MUCEN_MOUSE
θ value	1.06291 (rank : 551)	NC score	0.078619 (rank : 675)
Query Neighborhood Hits	808	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

NGL1_MOUSE
θ value	1.06291 (rank : 552)	NC score	0.018174 (rank : 1039)
Query Neighborhood Hits	808	Target Neighborhood Hits	512	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

SPIT1_MOUSE
θ value	1.06291 (rank : 553)	NC score	0.084788 (rank : 649)
Query Neighborhood Hits	808	Target Neighborhood Hits	96	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPR2A_MOUSE
θ value	1.06291 (rank : 554)	NC score	0.059953 (rank : 827)
Query Neighborhood Hits	808	Target Neighborhood Hits	35	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CQK8, O70553	Gene names	Sprr2a
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2A.

SPR2F_HUMAN
θ value	1.06291 (rank : 555)	NC score	0.105366 (rank : 578)
Query Neighborhood Hits	808	Target Neighborhood Hits	33	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

TNR1B_MOUSE
θ value	1.06291 (rank : 556)	NC score	0.093636 (rank : 625)
Query Neighborhood Hits	808	Target Neighborhood Hits	123	Shared Neighborhood Hits	68
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

UBP8_HUMAN
θ value	1.06291 (rank : 557)	NC score	0.004340 (rank : 1104)
Query Neighborhood Hits	808	Target Neighborhood Hits	751	Shared Neighborhood Hits	29
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

ADA19_MOUSE
θ value	1.38821 (rank : 558)	NC score	0.159763 (rank : 440)
Query Neighborhood Hits	808	Target Neighborhood Hits	315	Shared Neighborhood Hits	209
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA33_HUMAN
θ value	1.38821 (rank : 559)	NC score	0.152648 (rank : 455)
Query Neighborhood Hits	808	Target Neighborhood Hits	264	Shared Neighborhood Hits	182
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CTGF_MOUSE
θ value	1.38821 (rank : 560)	NC score	0.165486 (rank : 428)
Query Neighborhood Hits	808	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

ELTD1_HUMAN
θ value	1.38821 (rank : 561)	NC score	0.263169 (rank : 285)
Query Neighborhood Hits	808	Target Neighborhood Hits	269	Shared Neighborhood Hits	177
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ESM1_MOUSE
θ value	1.38821 (rank : 562)	NC score	0.156625 (rank : 448)
Query Neighborhood Hits	808	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA10_MOUSE
θ value	1.38821 (rank : 563)	NC score	0.209624 (rank : 335)
Query Neighborhood Hits	808	Target Neighborhood Hits	435	Shared Neighborhood Hits	240
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

HYAL3_MOUSE
θ value	1.38821 (rank : 564)	NC score	0.042139 (rank : 964)
Query Neighborhood Hits	808	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

ITB1_MOUSE
θ value	1.38821 (rank : 565)	NC score	0.323033 (rank : 262)
Query Neighborhood Hits	808	Target Neighborhood Hits	283	Shared Neighborhood Hits	242
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KR121_HUMAN
θ value	1.38821 (rank : 566)	NC score	0.095813 (rank : 614)
Query Neighborhood Hits	808	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	P59990	Gene names	KRTAP12-1, KAP12.1, KRTAP12.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-1 (Keratin-associated protein 12.1) (High sulfur keratin-associated protein 12.1).

KR413_HUMAN
θ value	1.38821 (rank : 567)	NC score	0.260743 (rank : 287)
Query Neighborhood Hits	808	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

LCE1A_HUMAN
θ value	1.38821 (rank : 568)	NC score	0.351830 (rank : 237)
Query Neighborhood Hits	808	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	1.38821 (rank : 569)	NC score	0.341151 (rank : 248)
Query Neighborhood Hits	808	Target Neighborhood Hits	58	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE3C_HUMAN
θ value	1.38821 (rank : 570)	NC score	0.125847 (rank : 516)
Query Neighborhood Hits	808	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

MATN4_MOUSE
θ value	1.38821 (rank : 571)	NC score	0.392760 (rank : 198)
Query Neighborhood Hits	808	Target Neighborhood Hits	277	Shared Neighborhood Hits	202
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

NSD1_MOUSE
θ value	1.38821 (rank : 572)	NC score	0.052643 (rank : 902)
Query Neighborhood Hits	808	Target Neighborhood Hits	472	Shared Neighborhood Hits	59
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PF21B_MOUSE
θ value	1.38821 (rank : 573)	NC score	0.051870 (rank : 913)
Query Neighborhood Hits	808	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PGH1_MOUSE
θ value	1.38821 (rank : 574)	NC score	0.129840 (rank : 502)
Query Neighborhood Hits	808	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

RET_HUMAN
θ value	1.38821 (rank : 575)	NC score	0.003343 (rank : 1110)
Query Neighborhood Hits	808	Target Neighborhood Hits	873	Shared Neighborhood Hits	40
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

SLK_HUMAN
θ value	1.38821 (rank : 576)	NC score	-0.010529 (rank : 1132)
Query Neighborhood Hits	808	Target Neighborhood Hits	1775	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

TAU_MOUSE
θ value	1.38821 (rank : 577)	NC score	0.085781 (rank : 645)
Query Neighborhood Hits	808	Target Neighborhood Hits	502	Shared Neighborhood Hits	55
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TIE2_MOUSE
θ value	1.38821 (rank : 578)	NC score	0.137876 (rank : 476)
Query Neighborhood Hits	808	Target Neighborhood Hits	1204	Shared Neighborhood Hits	289
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TTLL5_MOUSE
θ value	1.38821 (rank : 579)	NC score	0.011403 (rank : 1070)
Query Neighborhood Hits	808	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

VMDL3_HUMAN
θ value	1.38821 (rank : 580)	NC score	0.011246 (rank : 1071)
Query Neighborhood Hits	808	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N1M1, Q8N356, Q8NFT9, Q9BR80	Gene names	VMD2L3
Domain Architecture
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

ADA15_MOUSE
θ value	1.81305 (rank : 581)	NC score	0.179259 (rank : 398)
Query Neighborhood Hits	808	Target Neighborhood Hits	324	Shared Neighborhood Hits	234
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA22_HUMAN
θ value	1.81305 (rank : 582)	NC score	0.132140 (rank : 494)
Query Neighborhood Hits	808	Target Neighborhood Hits	211	Shared Neighborhood Hits	165
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ATS1_HUMAN
θ value	1.81305 (rank : 583)	NC score	0.063116 (rank : 793)
Query Neighborhood Hits	808	Target Neighborhood Hits	159	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

C163A_HUMAN
θ value	1.81305 (rank : 584)	NC score	0.008587 (rank : 1085)
Query Neighborhood Hits	808	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

IBP7_MOUSE
θ value	1.81305 (rank : 585)	NC score	0.050192 (rank : 935)
Query Neighborhood Hits	808	Target Neighborhood Hits	230	Shared Neighborhood Hits	54
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

KLH23_HUMAN
θ value	1.81305 (rank : 586)	NC score	0.003695 (rank : 1106)
Query Neighborhood Hits	808	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NBE8, Q8N9B9, Q96FT8	Gene names	KLHL23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

LCE2A_HUMAN
θ value	1.81305 (rank : 587)	NC score	0.217078 (rank : 322)
Query Neighborhood Hits	808	Target Neighborhood Hits	50	Shared Neighborhood Hits	36
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE3B_HUMAN
θ value	1.81305 (rank : 588)	NC score	0.240231 (rank : 309)
Query Neighborhood Hits	808	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LY6D_HUMAN
θ value	1.81305 (rank : 589)	NC score	0.030682 (rank : 996)
Query Neighborhood Hits	808	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q14210, O43783, Q8TBD4, Q92933	Gene names	LY6D, E48
Domain Architecture
Description	Lymphocyte antigen Ly-6D precursor (E48 antigen).

NUD12_HUMAN
θ value	1.81305 (rank : 590)	NC score	0.007301 (rank : 1090)
Query Neighborhood Hits	808	Target Neighborhood Hits	222	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

PTPRO_HUMAN
θ value	1.81305 (rank : 591)	NC score	0.036940 (rank : 983)
Query Neighborhood Hits	808	Target Neighborhood Hits	139	Shared Neighborhood Hits	26
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

RELN_MOUSE
θ value	1.81305 (rank : 592)	NC score	0.173294 (rank : 409)
Query Neighborhood Hits	808	Target Neighborhood Hits	235	Shared Neighborhood Hits	179
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

SPY4_MOUSE
θ value	1.81305 (rank : 593)	NC score	0.049351 (rank : 941)
Query Neighborhood Hits	808	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

TLL2_MOUSE
θ value	1.81305 (rank : 594)	NC score	0.202706 (rank : 350)
Query Neighborhood Hits	808	Target Neighborhood Hits	240	Shared Neighborhood Hits	159
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TNR3_MOUSE
θ value	1.81305 (rank : 595)	NC score	0.107340 (rank : 572)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR9_MOUSE
θ value	1.81305 (rank : 596)	NC score	0.159365 (rank : 442)
Query Neighborhood Hits	808	Target Neighborhood Hits	137	Shared Neighborhood Hits	103
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TULP4_HUMAN
θ value	1.81305 (rank : 597)	NC score	0.017274 (rank : 1041)
Query Neighborhood Hits	808	Target Neighborhood Hits	426	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

X3CL1_MOUSE
θ value	1.81305 (rank : 598)	NC score	0.024150 (rank : 1017)
Query Neighborhood Hits	808	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	O35188, O35933	Gene names	Cx3cl1, Cx3c, Fkn, Scyd1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

ZHX1_MOUSE
θ value	1.81305 (rank : 599)	NC score	0.016574 (rank : 1043)
Query Neighborhood Hits	808	Target Neighborhood Hits	334	Shared Neighborhood Hits	16
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

ZN185_MOUSE
θ value	1.81305 (rank : 600)	NC score	0.023114 (rank : 1023)
Query Neighborhood Hits	808	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q62394	Gene names	Znf185, Zfp185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein Zfp185) (P1-A).

AAK1_MOUSE
θ value	2.36792 (rank : 601)	NC score	0.003625 (rank : 1108)
Query Neighborhood Hits	808	Target Neighborhood Hits	1051	Shared Neighborhood Hits	67
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ADAM2_HUMAN
θ value	2.36792 (rank : 602)	NC score	0.129492 (rank : 504)
Query Neighborhood Hits	808	Target Neighborhood Hits	175	Shared Neighborhood Hits	143
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM9_MOUSE
θ value	2.36792 (rank : 603)	NC score	0.158578 (rank : 445)
Query Neighborhood Hits	808	Target Neighborhood Hits	325	Shared Neighborhood Hits	216
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

BRD8_MOUSE
θ value	2.36792 (rank : 604)	NC score	0.033783 (rank : 988)
Query Neighborhood Hits	808	Target Neighborhood Hits	422	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BSN_HUMAN
θ value	2.36792 (rank : 605)	NC score	0.053349 (rank : 894)
Query Neighborhood Hits	808	Target Neighborhood Hits	1537	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CADH3_MOUSE
θ value	2.36792 (rank : 606)	NC score	0.012809 (rank : 1061)
Query Neighborhood Hits	808	Target Neighborhood Hits	160	Shared Neighborhood Hits	15
SwissProt Accessions	P10287, Q61465	Gene names	Cdh3, Cdhp
Domain Architecture
Description	Cadherin-3 precursor (Placental-cadherin) (P-cadherin).

CN037_MOUSE
θ value	2.36792 (rank : 607)	NC score	0.066779 (rank : 750)
Query Neighborhood Hits	808	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

CO6_HUMAN
θ value	2.36792 (rank : 608)	NC score	0.184078 (rank : 382)
Query Neighborhood Hits	808	Target Neighborhood Hits	331	Shared Neighborhood Hits	185
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO8A_HUMAN
θ value	2.36792 (rank : 609)	NC score	0.129297 (rank : 505)
Query Neighborhood Hits	808	Target Neighborhood Hits	200	Shared Neighborhood Hits	119
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

DCR1A_HUMAN
θ value	2.36792 (rank : 610)	NC score	0.009639 (rank : 1081)
Query Neighborhood Hits	808	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PJP8, Q14701, Q6P5Y3, Q6PKL4	Gene names	DCLRE1A, KIAA0086, SNM1, SNM1A
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein (hSNM1) (hSNM1A).

FURIN_HUMAN
θ value	2.36792 (rank : 611)	NC score	0.060398 (rank : 821)
Query Neighborhood Hits	808	Target Neighborhood Hits	52	Shared Neighborhood Hits	26
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

KLH23_MOUSE
θ value	2.36792 (rank : 612)	NC score	0.002410 (rank : 1116)
Query Neighborhood Hits	808	Target Neighborhood Hits	188	Shared Neighborhood Hits	11
SwissProt Accessions	Q6GQU2, Q8C840	Gene names	Klhl23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

KRA24_HUMAN
θ value	2.36792 (rank : 613)	NC score	0.276966 (rank : 278)
Query Neighborhood Hits	808	Target Neighborhood Hits	192	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

LCE5A_HUMAN
θ value	2.36792 (rank : 614)	NC score	0.206598 (rank : 342)
Query Neighborhood Hits	808	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LCP2_HUMAN
θ value	2.36792 (rank : 615)	NC score	0.024202 (rank : 1016)
Query Neighborhood Hits	808	Target Neighborhood Hits	531	Shared Neighborhood Hits	40
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MT1A_HUMAN
θ value	2.36792 (rank : 616)	NC score	0.124798 (rank : 522)
Query Neighborhood Hits	808	Target Neighborhood Hits	74	Shared Neighborhood Hits	64
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1F_HUMAN
θ value	2.36792 (rank : 617)	NC score	0.095011 (rank : 619)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	65
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1L_HUMAN
θ value	2.36792 (rank : 618)	NC score	0.119240 (rank : 538)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	65
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

NFX1_HUMAN
θ value	2.36792 (rank : 619)	NC score	0.368433 (rank : 221)
Query Neighborhood Hits	808	Target Neighborhood Hits	405	Shared Neighborhood Hits	208
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NRG1_HUMAN
θ value	2.36792 (rank : 620)	NC score	0.125240 (rank : 521)
Query Neighborhood Hits	808	Target Neighborhood Hits	285	Shared Neighborhood Hits	97
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

PODXL_HUMAN
θ value	2.36792 (rank : 621)	NC score	0.115494 (rank : 544)
Query Neighborhood Hits	808	Target Neighborhood Hits	191	Shared Neighborhood Hits	50
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PRAX_MOUSE
θ value	2.36792 (rank : 622)	NC score	0.050041 (rank : 940)
Query Neighborhood Hits	808	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SEBP2_HUMAN
θ value	2.36792 (rank : 623)	NC score	0.014333 (rank : 1056)
Query Neighborhood Hits	808	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T21, Q8IYC0	Gene names	SECISBP2, SBP2
Domain Architecture
Description	SECIS-binding protein 2 (Selenocysteine insertion sequence-binding protein 2).

SOX30_HUMAN
θ value	2.36792 (rank : 624)	NC score	0.023977 (rank : 1018)
Query Neighborhood Hits	808	Target Neighborhood Hits	305	Shared Neighborhood Hits	30
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

TACC2_HUMAN
θ value	2.36792 (rank : 625)	NC score	0.027263 (rank : 1007)
Query Neighborhood Hits	808	Target Neighborhood Hits	856	Shared Neighborhood Hits	63
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TIP60_MOUSE
θ value	2.36792 (rank : 626)	NC score	0.014889 (rank : 1052)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

TNR1A_HUMAN
θ value	2.36792 (rank : 627)	NC score	0.103011 (rank : 590)
Query Neighborhood Hits	808	Target Neighborhood Hits	121	Shared Neighborhood Hits	65
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR22_MOUSE
θ value	2.36792 (rank : 628)	NC score	0.113019 (rank : 553)
Query Neighborhood Hits	808	Target Neighborhood Hits	97	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TRI42_MOUSE
θ value	2.36792 (rank : 629)	NC score	0.072857 (rank : 706)
Query Neighborhood Hits	808	Target Neighborhood Hits	316	Shared Neighborhood Hits	83
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ZHX1_HUMAN
θ value	2.36792 (rank : 630)	NC score	0.013586 (rank : 1058)
Query Neighborhood Hits	808	Target Neighborhood Hits	307	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKY1, Q8IWD8	Gene names	ZHX1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

ZN679_HUMAN
θ value	2.36792 (rank : 631)	NC score	-0.014415 (rank : 1134)
Query Neighborhood Hits	808	Target Neighborhood Hits	746	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IYX0	Gene names	ZNF679
Domain Architecture	No domain graphic available
Description	Zinc finger protein 679.

ADA11_MOUSE
θ value	3.0926 (rank : 632)	NC score	0.169181 (rank : 421)
Query Neighborhood Hits	808	Target Neighborhood Hits	263	Shared Neighborhood Hits	204
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA18_MOUSE
θ value	3.0926 (rank : 633)	NC score	0.160270 (rank : 439)
Query Neighborhood Hits	808	Target Neighborhood Hits	227	Shared Neighborhood Hits	192
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

COGA1_HUMAN
θ value	3.0926 (rank : 634)	NC score	0.040847 (rank : 971)
Query Neighborhood Hits	808	Target Neighborhood Hits	345	Shared Neighborhood Hits	46
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

EGFR_HUMAN
θ value	3.0926 (rank : 635)	NC score	0.025144 (rank : 1011)
Query Neighborhood Hits	808	Target Neighborhood Hits	939	Shared Neighborhood Hits	121
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EPHB3_HUMAN
θ value	3.0926 (rank : 636)	NC score	0.011784 (rank : 1068)
Query Neighborhood Hits	808	Target Neighborhood Hits	996	Shared Neighborhood Hits	94
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

GP110_MOUSE
θ value	3.0926 (rank : 637)	NC score	0.050368 (rank : 932)
Query Neighborhood Hits	808	Target Neighborhood Hits	92	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP123_HUMAN
θ value	3.0926 (rank : 638)	NC score	0.045144 (rank : 954)
Query Neighborhood Hits	808	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

HSPB1_MOUSE
θ value	3.0926 (rank : 639)	NC score	0.007367 (rank : 1088)
Query Neighborhood Hits	808	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P14602	Gene names	Hspb1, Hsp25, Hsp27
Domain Architecture
Description	Heat-shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27) (Growth-related 25 kDa protein) (P25) (HSP25).

LRP3_HUMAN
θ value	3.0926 (rank : 640)	NC score	0.199210 (rank : 356)
Query Neighborhood Hits	808	Target Neighborhood Hits	280	Shared Neighborhood Hits	137
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

MLL3_HUMAN
θ value	3.0926 (rank : 641)	NC score	0.076402 (rank : 689)
Query Neighborhood Hits	808	Target Neighborhood Hits	1644	Shared Neighborhood Hits	163
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PALB2_MOUSE
θ value	3.0926 (rank : 642)	NC score	0.028439 (rank : 1004)
Query Neighborhood Hits	808	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

PGCA_MOUSE
θ value	3.0926 (rank : 643)	NC score	0.078849 (rank : 674)
Query Neighborhood Hits	808	Target Neighborhood Hits	643	Shared Neighborhood Hits	71
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

RSPO4_HUMAN
θ value	3.0926 (rank : 644)	NC score	0.128546 (rank : 506)
Query Neighborhood Hits	808	Target Neighborhood Hits	110	Shared Neighborhood Hits	86
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SPR2E_HUMAN
θ value	3.0926 (rank : 645)	NC score	0.079841 (rank : 669)
Query Neighborhood Hits	808	Target Neighborhood Hits	32	Shared Neighborhood Hits	20
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPY1_HUMAN
θ value	3.0926 (rank : 646)	NC score	0.046267 (rank : 951)
Query Neighborhood Hits	808	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

SUSD1_HUMAN
θ value	3.0926 (rank : 647)	NC score	0.463556 (rank : 142)
Query Neighborhood Hits	808	Target Neighborhood Hits	285	Shared Neighborhood Hits	220
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TINAG_HUMAN
θ value	3.0926 (rank : 648)	NC score	0.069237 (rank : 738)
Query Neighborhood Hits	808	Target Neighborhood Hits	63	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

UBR1_HUMAN
θ value	3.0926 (rank : 649)	NC score	0.006315 (rank : 1095)
Query Neighborhood Hits	808	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

WFDC2_HUMAN
θ value	3.0926 (rank : 650)	NC score	0.104728 (rank : 581)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	57
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

AD26A_MOUSE
θ value	4.03905 (rank : 651)	NC score	0.106519 (rank : 576)
Query Neighborhood Hits	808	Target Neighborhood Hits	165	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA28_HUMAN
θ value	4.03905 (rank : 652)	NC score	0.138129 (rank : 475)
Query Neighborhood Hits	808	Target Neighborhood Hits	244	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADAM9_HUMAN
θ value	4.03905 (rank : 653)	NC score	0.148763 (rank : 460)
Query Neighborhood Hits	808	Target Neighborhood Hits	243	Shared Neighborhood Hits	196
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ASXL1_MOUSE
θ value	4.03905 (rank : 654)	NC score	0.020381 (rank : 1033)
Query Neighborhood Hits	808	Target Neighborhood Hits	182	Shared Neighborhood Hits	16
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

ATL3_HUMAN
θ value	4.03905 (rank : 655)	NC score	0.060910 (rank : 817)
Query Neighborhood Hits	808	Target Neighborhood Hits	414	Shared Neighborhood Hits	91
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATRN_HUMAN
θ value	4.03905 (rank : 656)	NC score	0.322718 (rank : 263)
Query Neighborhood Hits	808	Target Neighborhood Hits	525	Shared Neighborhood Hits	298
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

CCNB2_MOUSE
θ value	4.03905 (rank : 657)	NC score	0.003239 (rank : 1111)
Query Neighborhood Hits	808	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P30276	Gene names	Ccnb2, Cycb2
Domain Architecture
Description	G2/mitotic-specific cyclin-B2.

CP135_MOUSE
θ value	4.03905 (rank : 658)	NC score	0.001065 (rank : 1119)
Query Neighborhood Hits	808	Target Neighborhood Hits	1278	Shared Neighborhood Hits	46
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DCP1A_HUMAN
θ value	4.03905 (rank : 659)	NC score	0.046676 (rank : 949)
Query Neighborhood Hits	808	Target Neighborhood Hits	228	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

ESM1_HUMAN
θ value	4.03905 (rank : 660)	NC score	0.174831 (rank : 407)
Query Neighborhood Hits	808	Target Neighborhood Hits	110	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

EZH2_HUMAN
θ value	4.03905 (rank : 661)	NC score	0.036993 (rank : 981)
Query Neighborhood Hits	808	Target Neighborhood Hits	84	Shared Neighborhood Hits	38
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	4.03905 (rank : 662)	NC score	0.037835 (rank : 979)
Query Neighborhood Hits	808	Target Neighborhood Hits	86	Shared Neighborhood Hits	40
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

GFRAL_MOUSE
θ value	4.03905 (rank : 663)	NC score	0.035607 (rank : 986)
Query Neighborhood Hits	808	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GP156_MOUSE
θ value	4.03905 (rank : 664)	NC score	0.015133 (rank : 1050)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

IC1_MOUSE
θ value	4.03905 (rank : 665)	NC score	0.005319 (rank : 1099)
Query Neighborhood Hits	808	Target Neighborhood Hits	164	Shared Neighborhood Hits	14
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

IL6_MOUSE
θ value	4.03905 (rank : 666)	NC score	0.014522 (rank : 1055)
Query Neighborhood Hits	808	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	P08505, Q3UCQ0, Q8BN26	Gene names	Il6, Il-6
Domain Architecture
Description	Interleukin-6 precursor (IL-6) (Interleukin HP-1) (B-cell hybridoma growth factor).

JHD3B_HUMAN
θ value	4.03905 (rank : 667)	NC score	0.004808 (rank : 1103)
Query Neighborhood Hits	808	Target Neighborhood Hits	128	Shared Neighborhood Hits	17
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

KALM_HUMAN
θ value	4.03905 (rank : 668)	NC score	0.035698 (rank : 984)
Query Neighborhood Hits	808	Target Neighborhood Hits	114	Shared Neighborhood Hits	33
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

MAP2_MOUSE
θ value	4.03905 (rank : 669)	NC score	0.042907 (rank : 961)
Query Neighborhood Hits	808	Target Neighborhood Hits	342	Shared Neighborhood Hits	38
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

NBR1_MOUSE
θ value	4.03905 (rank : 670)	NC score	0.009658 (rank : 1080)
Query Neighborhood Hits	808	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

NFAC1_HUMAN
θ value	4.03905 (rank : 671)	NC score	0.025667 (rank : 1010)
Query Neighborhood Hits	808	Target Neighborhood Hits	312	Shared Neighborhood Hits	44
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

PALB2_HUMAN
θ value	4.03905 (rank : 672)	NC score	0.017563 (rank : 1040)
Query Neighborhood Hits	808	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

PLXB1_HUMAN
θ value	4.03905 (rank : 673)	NC score	0.022387 (rank : 1026)
Query Neighborhood Hits	808	Target Neighborhood Hits	360	Shared Neighborhood Hits	49
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

RSPO3_HUMAN
θ value	4.03905 (rank : 674)	NC score	0.142681 (rank : 468)
Query Neighborhood Hits	808	Target Neighborhood Hits	128	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

SENP7_HUMAN
θ value	4.03905 (rank : 675)	NC score	0.010639 (rank : 1075)
Query Neighborhood Hits	808	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

SMG7_MOUSE
θ value	4.03905 (rank : 676)	NC score	0.015189 (rank : 1049)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	20
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

TLL1_HUMAN
θ value	4.03905 (rank : 677)	NC score	0.201243 (rank : 351)
Query Neighborhood Hits	808	Target Neighborhood Hits	236	Shared Neighborhood Hits	155
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TMF1_HUMAN
θ value	4.03905 (rank : 678)	NC score	0.006624 (rank : 1093)
Query Neighborhood Hits	808	Target Neighborhood Hits	987	Shared Neighborhood Hits	42
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TPA_MOUSE
θ value	4.03905 (rank : 679)	NC score	0.103310 (rank : 586)
Query Neighborhood Hits	808	Target Neighborhood Hits	335	Shared Neighborhood Hits	145
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRIM3_MOUSE
θ value	4.03905 (rank : 680)	NC score	-0.002200 (rank : 1125)
Query Neighborhood Hits	808	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

ABCG5_MOUSE
θ value	5.27518 (rank : 681)	NC score	-0.001091 (rank : 1123)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PE8	Gene names	Abcg5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ANK2_HUMAN
θ value	5.27518 (rank : 682)	NC score	0.063220 (rank : 791)
Query Neighborhood Hits	808	Target Neighborhood Hits	1615	Shared Neighborhood Hits	119
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ATS16_MOUSE
θ value	5.27518 (rank : 683)	NC score	0.068230 (rank : 743)
Query Neighborhood Hits	808	Target Neighborhood Hits	179	Shared Neighborhood Hits	99
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

BTC_HUMAN
θ value	5.27518 (rank : 684)	NC score	0.066173 (rank : 757)
Query Neighborhood Hits	808	Target Neighborhood Hits	70	Shared Neighborhood Hits	46
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CADH3_HUMAN
θ value	5.27518 (rank : 685)	NC score	0.011846 (rank : 1067)
Query Neighborhood Hits	808	Target Neighborhood Hits	159	Shared Neighborhood Hits	12
SwissProt Accessions	P22223	Gene names	CDH3, CDHP
Domain Architecture
Description	Cadherin-3 precursor (Placental-cadherin) (P-cadherin).

CO002_HUMAN
θ value	5.27518 (rank : 686)	NC score	0.085136 (rank : 647)
Query Neighborhood Hits	808	Target Neighborhood Hits	387	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CSPG5_HUMAN
θ value	5.27518 (rank : 687)	NC score	0.047351 (rank : 946)
Query Neighborhood Hits	808	Target Neighborhood Hits	199	Shared Neighborhood Hits	38
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

EPHB3_MOUSE
θ value	5.27518 (rank : 688)	NC score	0.009976 (rank : 1078)
Query Neighborhood Hits	808	Target Neighborhood Hits	996	Shared Neighborhood Hits	93
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

ERBB3_HUMAN
θ value	5.27518 (rank : 689)	NC score	0.033070 (rank : 989)
Query Neighborhood Hits	808	Target Neighborhood Hits	918	Shared Neighborhood Hits	122
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

FAM5B_HUMAN
θ value	5.27518 (rank : 690)	NC score	0.025733 (rank : 1008)
Query Neighborhood Hits	808	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

FAM5B_MOUSE
θ value	5.27518 (rank : 691)	NC score	0.029724 (rank : 1000)
Query Neighborhood Hits	808	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

GAS1_HUMAN
θ value	5.27518 (rank : 692)	NC score	0.021377 (rank : 1028)
Query Neighborhood Hits	808	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P54826	Gene names	GAS1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

GFRAL_HUMAN
θ value	5.27518 (rank : 693)	NC score	0.021102 (rank : 1030)
Query Neighborhood Hits	808	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UXV0, Q5VTF6	Gene names	GFRAL
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

HELI_MOUSE
θ value	5.27518 (rank : 694)	NC score	-0.014475 (rank : 1135)
Query Neighborhood Hits	808	Target Neighborhood Hits	746	Shared Neighborhood Hits	10
SwissProt Accessions	P81183	Gene names	Ikzf2, Helios, Zfpn1a2, Znfn1a2
Domain Architecture	No domain graphic available
Description	Zinc finger protein Helios (IKAROS family zinc finger protein 2).

HNF1A_MOUSE
θ value	5.27518 (rank : 695)	NC score	0.041517 (rank : 967)
Query Neighborhood Hits	808	Target Neighborhood Hits	212	Shared Neighborhood Hits	28
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

K0586_HUMAN
θ value	5.27518 (rank : 696)	NC score	0.024425 (rank : 1014)
Query Neighborhood Hits	808	Target Neighborhood Hits	311	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

LCE1D_HUMAN
θ value	5.27518 (rank : 697)	NC score	0.271040 (rank : 281)
Query Neighborhood Hits	808	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LRP5_MOUSE
θ value	5.27518 (rank : 698)	NC score	0.250402 (rank : 296)
Query Neighborhood Hits	808	Target Neighborhood Hits	236	Shared Neighborhood Hits	152
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

MSMB_MOUSE
θ value	5.27518 (rank : 699)	NC score	0.052054 (rank : 909)
Query Neighborhood Hits	808	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	O08540	Gene names	Msmb, Psp94
Domain Architecture
Description	Beta-microseminoprotein precursor (Prostate secreted seminal plasma protein) (Prostate secretory protein PSP94) (PSP-94).

MT1E_HUMAN
θ value	5.27518 (rank : 700)	NC score	0.091112 (rank : 632)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

PRP40_MOUSE
θ value	5.27518 (rank : 701)	NC score	0.012076 (rank : 1064)
Query Neighborhood Hits	808	Target Neighborhood Hits	447	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RBL2_MOUSE
θ value	5.27518 (rank : 702)	NC score	0.009428 (rank : 1082)
Query Neighborhood Hits	808	Target Neighborhood Hits	40	Shared Neighborhood Hits	11
SwissProt Accessions	Q64700	Gene names	Rbl2
Domain Architecture
Description	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (PRB2) (P130) (RBR-2).

RSPO1_HUMAN
θ value	5.27518 (rank : 703)	NC score	0.095397 (rank : 616)
Query Neighborhood Hits	808	Target Neighborhood Hits	101	Shared Neighborhood Hits	66
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

SEPT9_MOUSE
θ value	5.27518 (rank : 704)	NC score	0.008792 (rank : 1084)
Query Neighborhood Hits	808	Target Neighborhood Hits	238	Shared Neighborhood Hits	23
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SPR2K_MOUSE
θ value	5.27518 (rank : 705)	NC score	0.053817 (rank : 886)
Query Neighborhood Hits	808	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	O70562	Gene names	Sprr2k
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2K.

THYG_MOUSE
θ value	5.27518 (rank : 706)	NC score	0.043050 (rank : 959)
Query Neighborhood Hits	808	Target Neighborhood Hits	161	Shared Neighborhood Hits	69
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TIP60_HUMAN
θ value	5.27518 (rank : 707)	NC score	0.012978 (rank : 1060)
Query Neighborhood Hits	808	Target Neighborhood Hits	90	Shared Neighborhood Hits	17
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TLL1_MOUSE
θ value	5.27518 (rank : 708)	NC score	0.205444 (rank : 346)
Query Neighborhood Hits	808	Target Neighborhood Hits	237	Shared Neighborhood Hits	159
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TNR16_HUMAN
θ value	5.27518 (rank : 709)	NC score	0.170839 (rank : 416)
Query Neighborhood Hits	808	Target Neighborhood Hits	183	Shared Neighborhood Hits	127
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TSP4_HUMAN
θ value	5.27518 (rank : 710)	NC score	0.413699 (rank : 184)
Query Neighborhood Hits	808	Target Neighborhood Hits	277	Shared Neighborhood Hits	237
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TXND2_MOUSE
θ value	5.27518 (rank : 711)	NC score	0.024406 (rank : 1015)
Query Neighborhood Hits	808	Target Neighborhood Hits	828	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UBP20_HUMAN
θ value	5.27518 (rank : 712)	NC score	0.001201 (rank : 1118)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

VASN_MOUSE
θ value	5.27518 (rank : 713)	NC score	0.087368 (rank : 643)
Query Neighborhood Hits	808	Target Neighborhood Hits	426	Shared Neighborhood Hits	126
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

WFDC5_HUMAN
θ value	5.27518 (rank : 714)	NC score	0.057983 (rank : 851)
Query Neighborhood Hits	808	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TCV5, Q6UWE4	Gene names	WFDC5, WAP1
Domain Architecture
Description	WAP four-disulfide core domain protein 5 precursor (Putative protease inhibitor WAP1).

ZN588_HUMAN
θ value	5.27518 (rank : 715)	NC score	-0.015006 (rank : 1137)
Query Neighborhood Hits	808	Target Neighborhood Hits	759	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UII5	Gene names	ZNF588, ZFD25
Domain Architecture	No domain graphic available
Description	Zinc finger protein 588 (Zinc finger protein ZFD25).

ADA11_HUMAN
θ value	6.88961 (rank : 716)	NC score	0.167596 (rank : 422)
Query Neighborhood Hits	808	Target Neighborhood Hits	259	Shared Neighborhood Hits	203
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA23_MOUSE
θ value	6.88961 (rank : 717)	NC score	0.161866 (rank : 435)
Query Neighborhood Hits	808	Target Neighborhood Hits	245	Shared Neighborhood Hits	209
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ARHGA_HUMAN
θ value	6.88961 (rank : 718)	NC score	-0.000535 (rank : 1121)
Query Neighborhood Hits	808	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ATRN_MOUSE
θ value	6.88961 (rank : 719)	NC score	0.324313 (rank : 260)
Query Neighborhood Hits	808	Target Neighborhood Hits	519	Shared Neighborhood Hits	296
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ATX7_MOUSE
θ value	6.88961 (rank : 720)	NC score	0.015876 (rank : 1046)
Query Neighborhood Hits	808	Target Neighborhood Hits	328	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CD017_HUMAN
θ value	6.88961 (rank : 721)	NC score	0.013728 (rank : 1057)
Query Neighborhood Hits	808	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q53FE4, Q6FI84, Q6IS77, Q9H0D9	Gene names	C4orf17
Domain Architecture	No domain graphic available
Description	Protein C4orf17.

CD177_HUMAN
θ value	6.88961 (rank : 722)	NC score	0.008884 (rank : 1083)
Query Neighborhood Hits	808	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N6Q3, Q711Q2, Q8NCV9, Q96QH1, Q9HDA5	Gene names	CD177, NB1, PRV1
Domain Architecture	No domain graphic available
Description	CD177 antigen precursor (Polycythemia rubra vera protein 1) (PRV-1) (NB1 glycoprotein) (NB1 GP) (Human neutrophil alloantigen 2a) (HNA- 2a).

CD5_MOUSE
θ value	6.88961 (rank : 723)	NC score	0.007539 (rank : 1087)
Query Neighborhood Hits	808	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	P13379	Gene names	Cd5, Ly-1
Domain Architecture
Description	T-cell surface glycoprotein CD5 precursor (Lymphocyte antigen Ly-1) (Lyt-1).

COFA1_HUMAN
θ value	6.88961 (rank : 724)	NC score	0.031915 (rank : 994)
Query Neighborhood Hits	808	Target Neighborhood Hits	292	Shared Neighborhood Hits	39
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

CR2_MOUSE
θ value	6.88961 (rank : 725)	NC score	0.052985 (rank : 897)
Query Neighborhood Hits	808	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

DCC_MOUSE
θ value	6.88961 (rank : 726)	NC score	0.055759 (rank : 867)
Query Neighborhood Hits	808	Target Neighborhood Hits	896	Shared Neighborhood Hits	103
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

EGFL7_HUMAN
θ value	6.88961 (rank : 727)	NC score	0.466014 (rank : 141)
Query Neighborhood Hits	808	Target Neighborhood Hits	325	Shared Neighborhood Hits	262
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

ELF4_HUMAN
θ value	6.88961 (rank : 728)	NC score	0.018763 (rank : 1037)
Query Neighborhood Hits	808	Target Neighborhood Hits	87	Shared Neighborhood Hits	13
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

EPHA4_MOUSE
θ value	6.88961 (rank : 729)	NC score	0.010566 (rank : 1076)
Query Neighborhood Hits	808	Target Neighborhood Hits	982	Shared Neighborhood Hits	93
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

ERBB4_HUMAN
θ value	6.88961 (rank : 730)	NC score	0.023683 (rank : 1020)
Query Neighborhood Hits	808	Target Neighborhood Hits	910	Shared Neighborhood Hits	103
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

FSTL1_MOUSE
θ value	6.88961 (rank : 731)	NC score	0.079009 (rank : 673)
Query Neighborhood Hits	808	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

GPVI_HUMAN
θ value	6.88961 (rank : 732)	NC score	0.003096 (rank : 1112)
Query Neighborhood Hits	808	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HCN6, Q9HCN7, Q9UIF2	Gene names	GP6, GPVI
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein VI precursor.

HSF1_MOUSE
θ value	6.88961 (rank : 733)	NC score	0.024926 (rank : 1013)
Query Neighborhood Hits	808	Target Neighborhood Hits	267	Shared Neighborhood Hits	18
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

INVS_HUMAN
θ value	6.88961 (rank : 734)	NC score	0.037019 (rank : 980)
Query Neighborhood Hits	808	Target Neighborhood Hits	455	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

INVS_MOUSE
θ value	6.88961 (rank : 735)	NC score	0.038448 (rank : 977)
Query Neighborhood Hits	808	Target Neighborhood Hits	609	Shared Neighborhood Hits	32
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

K1958_MOUSE
θ value	6.88961 (rank : 736)	NC score	0.011723 (rank : 1069)
Query Neighborhood Hits	808	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C4P0, Q8BN62, Q8K1X8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1958 homolog.

KR123_HUMAN
θ value	6.88961 (rank : 737)	NC score	0.183822 (rank : 385)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	64
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

KR241_HUMAN
θ value	6.88961 (rank : 738)	NC score	0.110951 (rank : 562)
Query Neighborhood Hits	808	Target Neighborhood Hits	71	Shared Neighborhood Hits	55
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

LPP_HUMAN
θ value	6.88961 (rank : 739)	NC score	0.025730 (rank : 1009)
Query Neighborhood Hits	808	Target Neighborhood Hits	775	Shared Neighborhood Hits	53
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

LRP6_HUMAN
θ value	6.88961 (rank : 740)	NC score	0.251288 (rank : 293)
Query Neighborhood Hits	808	Target Neighborhood Hits	235	Shared Neighborhood Hits	155
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	6.88961 (rank : 741)	NC score	0.249480 (rank : 297)
Query Neighborhood Hits	808	Target Neighborhood Hits	232	Shared Neighborhood Hits	152
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRRC4_HUMAN
θ value	6.88961 (rank : 742)	NC score	0.014631 (rank : 1054)
Query Neighborhood Hits	808	Target Neighborhood Hits	444	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

MT1B_HUMAN
θ value	6.88961 (rank : 743)	NC score	0.125982 (rank : 514)
Query Neighborhood Hits	808	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1I_HUMAN
θ value	6.88961 (rank : 744)	NC score	0.071303 (rank : 721)
Query Neighborhood Hits	808	Target Neighborhood Hits	64	Shared Neighborhood Hits	57
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

MT1M_HUMAN
θ value	6.88961 (rank : 745)	NC score	0.075146 (rank : 700)
Query Neighborhood Hits	808	Target Neighborhood Hits	72	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

MT1X_HUMAN
θ value	6.88961 (rank : 746)	NC score	0.113605 (rank : 549)
Query Neighborhood Hits	808	Target Neighborhood Hits	76	Shared Neighborhood Hits	68
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT2_HUMAN
θ value	6.88961 (rank : 747)	NC score	0.079561 (rank : 670)
Query Neighborhood Hits	808	Target Neighborhood Hits	69	Shared Neighborhood Hits	62
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

MUC13_MOUSE
θ value	6.88961 (rank : 748)	NC score	0.244091 (rank : 302)
Query Neighborhood Hits	808	Target Neighborhood Hits	447	Shared Neighborhood Hits	206
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

NAT6_HUMAN
θ value	6.88961 (rank : 749)	NC score	0.010309 (rank : 1077)
Query Neighborhood Hits	808	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q93015, Q93014	Gene names	NAT6, FUS2
Domain Architecture
Description	N-acetyltransferase 6 (EC 2.3.1.-) (Fus-2 protein) (Fusion 2 protein).

NTNG2_HUMAN
θ value	6.88961 (rank : 750)	NC score	0.348616 (rank : 239)
Query Neighborhood Hits	808	Target Neighborhood Hits	276	Shared Neighborhood Hits	224
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

OC90_HUMAN
θ value	6.88961 (rank : 751)	NC score	0.023155 (rank : 1022)
Query Neighborhood Hits	808	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	Q02509	Gene names	OC90, PLA2L
Domain Architecture
Description	Otoconin 90 precursor (Oc90) (Phospholipase A2 homolog).

RC3H1_HUMAN
θ value	6.88961 (rank : 752)	NC score	0.008472 (rank : 1086)
Query Neighborhood Hits	808	Target Neighborhood Hits	433	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RET_MOUSE
θ value	6.88961 (rank : 753)	NC score	0.002937 (rank : 1113)
Query Neighborhood Hits	808	Target Neighborhood Hits	884	Shared Neighborhood Hits	45
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RGS3_MOUSE
θ value	6.88961 (rank : 754)	NC score	0.046670 (rank : 950)
Query Neighborhood Hits	808	Target Neighborhood Hits	1621	Shared Neighborhood Hits	122
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SEM6D_MOUSE
θ value	6.88961 (rank : 755)	NC score	0.007021 (rank : 1092)
Query Neighborhood Hits	808	Target Neighborhood Hits	161	Shared Neighborhood Hits	14
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SPY3_HUMAN
θ value	6.88961 (rank : 756)	NC score	0.040520 (rank : 972)
Query Neighborhood Hits	808	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	O43610	Gene names	SPRY3
Domain Architecture
Description	Sprouty homolog 3 (Spry-3).

TNR17_HUMAN
θ value	6.88961 (rank : 757)	NC score	0.011984 (rank : 1065)
Query Neighborhood Hits	808	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q02223	Gene names	TNFRSF17, BCM, BCMA
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD269 antigen).

TSP3_MOUSE
θ value	6.88961 (rank : 758)	NC score	0.383622 (rank : 204)
Query Neighborhood Hits	808	Target Neighborhood Hits	247	Shared Neighborhood Hits	214
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

VEGFD_HUMAN
θ value	6.88961 (rank : 759)	NC score	0.030318 (rank : 997)
Query Neighborhood Hits	808	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	O43915	Gene names	FIGF, VEGFD
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

WWP1_MOUSE
θ value	6.88961 (rank : 760)	NC score	0.005190 (rank : 1100)
Query Neighborhood Hits	808	Target Neighborhood Hits	138	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

AAK1_HUMAN
θ value	8.99809 (rank : 761)	NC score	0.002562 (rank : 1115)
Query Neighborhood Hits	808	Target Neighborhood Hits	1077	Shared Neighborhood Hits	69
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ADA21_HUMAN
θ value	8.99809 (rank : 762)	NC score	0.123147 (rank : 526)
Query Neighborhood Hits	808	Target Neighborhood Hits	181	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ATF1_HUMAN
θ value	8.99809 (rank : 763)	NC score	0.005856 (rank : 1097)
Query Neighborhood Hits	808	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	P18846, P25168	Gene names	ATF1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TREB36 protein).

ATS14_HUMAN
θ value	8.99809 (rank : 764)	NC score	0.065328 (rank : 765)
Query Neighborhood Hits	808	Target Neighborhood Hits	382	Shared Neighborhood Hits	106
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS2_HUMAN
θ value	8.99809 (rank : 765)	NC score	0.055590 (rank : 870)
Query Neighborhood Hits	808	Target Neighborhood Hits	179	Shared Neighborhood Hits	82
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS7_HUMAN
θ value	8.99809 (rank : 766)	NC score	0.070686 (rank : 726)
Query Neighborhood Hits	808	Target Neighborhood Hits	169	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

BCL9_HUMAN
θ value	8.99809 (rank : 767)	NC score	0.041798 (rank : 965)
Query Neighborhood Hits	808	Target Neighborhood Hits	1008	Shared Neighborhood Hits	83
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CDAN1_HUMAN
θ value	8.99809 (rank : 768)	NC score	0.020768 (rank : 1032)
Query Neighborhood Hits	808	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

CP270_MOUSE
θ value	8.99809 (rank : 769)	NC score	-0.004883 (rank : 1128)
Query Neighborhood Hits	808	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	Q91W64, Q5GLY9, Q80VW0, Q8R120, Q8VC00	Gene names	Cyp2c70, Cyp2c-70, Cyp2c22
Domain Architecture	No domain graphic available
Description	Cytochrome P450 2C70 (EC 1.14.14.1) (CYPIIC70).

CT127_HUMAN
θ value	8.99809 (rank : 770)	NC score	0.126901 (rank : 509)
Query Neighborhood Hits	808	Target Neighborhood Hits	67	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

DSG2_MOUSE
θ value	8.99809 (rank : 771)	NC score	0.012254 (rank : 1063)
Query Neighborhood Hits	808	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	O55111, Q8K069, Q8R517	Gene names	Dsg2
Domain Architecture
Description	Desmoglein-2 precursor.

DTBP1_MOUSE
θ value	8.99809 (rank : 772)	NC score	0.002095 (rank : 1117)
Query Neighborhood Hits	808	Target Neighborhood Hits	209	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

EGR2_HUMAN
θ value	8.99809 (rank : 773)	NC score	-0.014882 (rank : 1136)
Query Neighborhood Hits	808	Target Neighborhood Hits	728	Shared Neighborhood Hits	15
SwissProt Accessions	P11161, Q8IV26, Q9UNA6	Gene names	EGR2, KROX20
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein) (AT591).

EPHB4_MOUSE
θ value	8.99809 (rank : 774)	NC score	0.023695 (rank : 1019)
Query Neighborhood Hits	808	Target Neighborhood Hits	1013	Shared Neighborhood Hits	139
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

FHR1_HUMAN
θ value	8.99809 (rank : 775)	NC score	0.036972 (rank : 982)
Query Neighborhood Hits	808	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

FSTL1_HUMAN
θ value	8.99809 (rank : 776)	NC score	0.082409 (rank : 656)
Query Neighborhood Hits	808	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

GAS1_MOUSE
θ value	8.99809 (rank : 777)	NC score	0.019938 (rank : 1034)
Query Neighborhood Hits	808	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q01721	Gene names	Gas1, Gas-1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

GTF2I_HUMAN
θ value	8.99809 (rank : 778)	NC score	0.014927 (rank : 1051)
Query Neighborhood Hits	808	Target Neighborhood Hits	151	Shared Neighborhood Hits	10
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

GTF2I_MOUSE
θ value	8.99809 (rank : 779)	NC score	0.010712 (rank : 1074)
Query Neighborhood Hits	808	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

HHIP_HUMAN
θ value	8.99809 (rank : 780)	NC score	0.380992 (rank : 211)
Query Neighborhood Hits	808	Target Neighborhood Hits	249	Shared Neighborhood Hits	223
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HMGA2_MOUSE
θ value	8.99809 (rank : 781)	NC score	0.015703 (rank : 1047)
Query Neighborhood Hits	808	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	P52927, Q3UQW0	Gene names	Hmga2, Hmgic
Domain Architecture	No domain graphic available
Description	High mobility group protein HMGI-C (High mobility group AT-hook protein 2).

LYAM1_HUMAN
θ value	8.99809 (rank : 782)	NC score	0.226519 (rank : 316)
Query Neighborhood Hits	808	Target Neighborhood Hits	315	Shared Neighborhood Hits	199
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

M4K1_HUMAN
θ value	8.99809 (rank : 783)	NC score	-0.010427 (rank : 1131)
Query Neighborhood Hits	808	Target Neighborhood Hits	884	Shared Neighborhood Hits	32
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

MDM2_MOUSE
θ value	8.99809 (rank : 784)	NC score	0.003675 (rank : 1107)
Query Neighborhood Hits	808	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

MLL2_HUMAN
θ value	8.99809 (rank : 785)	NC score	0.074990 (rank : 701)
Query Neighborhood Hits	808	Target Neighborhood Hits	1788	Shared Neighborhood Hits	169
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MTF2_HUMAN
θ value	8.99809 (rank : 786)	NC score	0.005079 (rank : 1101)
Query Neighborhood Hits	808	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	8.99809 (rank : 787)	NC score	0.005516 (rank : 1098)
Query Neighborhood Hits	808	Target Neighborhood Hits	126	Shared Neighborhood Hits	12
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

NPAS4_HUMAN
θ value	8.99809 (rank : 788)	NC score	0.032079 (rank : 992)
Query Neighborhood Hits	808	Target Neighborhood Hits	214	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

OR6N2_HUMAN
θ value	8.99809 (rank : 789)	NC score	-0.015315 (rank : 1138)
Query Neighborhood Hits	808	Target Neighborhood Hits	698	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGY6	Gene names	OR6N2
Domain Architecture
Description	Olfactory receptor 6N2.

PARC_MOUSE
θ value	8.99809 (rank : 790)	NC score	0.010956 (rank : 1072)
Query Neighborhood Hits	808	Target Neighborhood Hits	114	Shared Neighborhood Hits	14
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

PARM1_HUMAN
θ value	8.99809 (rank : 791)	NC score	0.048668 (rank : 943)
Query Neighborhood Hits	808	Target Neighborhood Hits	86	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PCSK4_HUMAN
θ value	8.99809 (rank : 792)	NC score	0.056696 (rank : 860)
Query Neighborhood Hits	808	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

PER3_HUMAN
θ value	8.99809 (rank : 793)	NC score	0.039259 (rank : 975)
Query Neighborhood Hits	808	Target Neighborhood Hits	479	Shared Neighborhood Hits	45
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PHF12_HUMAN
θ value	8.99809 (rank : 794)	NC score	0.014818 (rank : 1053)
Query Neighborhood Hits	808	Target Neighborhood Hits	174	Shared Neighborhood Hits	24
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PKHA4_MOUSE
θ value	8.99809 (rank : 795)	NC score	0.007141 (rank : 1091)
Query Neighborhood Hits	808	Target Neighborhood Hits	202	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PO6F1_MOUSE
θ value	8.99809 (rank : 796)	NC score	0.010861 (rank : 1073)
Query Neighborhood Hits	808	Target Neighborhood Hits	581	Shared Neighborhood Hits	29
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

RBL2_HUMAN
θ value	8.99809 (rank : 797)	NC score	0.006574 (rank : 1094)
Query Neighborhood Hits	808	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q08999, Q15073, Q16084, Q92812	Gene names	RBL2, RB2
Domain Architecture
Description	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (PRB2) (P130) (RBR-2).

RKHD1_HUMAN
θ value	8.99809 (rank : 798)	NC score	0.009689 (rank : 1079)
Query Neighborhood Hits	808	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

ROBO3_HUMAN
θ value	8.99809 (rank : 799)	NC score	0.032436 (rank : 991)
Query Neighborhood Hits	808	Target Neighborhood Hits	570	Shared Neighborhood Hits	65
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

RXFP2_MOUSE
θ value	8.99809 (rank : 800)	NC score	0.027590 (rank : 1005)
Query Neighborhood Hits	808	Target Neighborhood Hits	760	Shared Neighborhood Hits	50
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

SO1C1_MOUSE
θ value	8.99809 (rank : 801)	NC score	0.003348 (rank : 1109)
Query Neighborhood Hits	808	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

SVIL_MOUSE
θ value	8.99809 (rank : 802)	NC score	0.016611 (rank : 1042)
Query Neighborhood Hits	808	Target Neighborhood Hits	439	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TGFA_MOUSE
θ value	8.99809 (rank : 803)	NC score	0.044785 (rank : 956)
Query Neighborhood Hits	808	Target Neighborhood Hits	62	Shared Neighborhood Hits	38
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TICN3_HUMAN
θ value	8.99809 (rank : 804)	NC score	0.019021 (rank : 1036)
Query Neighborhood Hits	808	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TRAF7_HUMAN
θ value	8.99809 (rank : 805)	NC score	-0.000901 (rank : 1122)
Query Neighborhood Hits	808	Target Neighborhood Hits	482	Shared Neighborhood Hits	13
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TSP4_MOUSE
θ value	8.99809 (rank : 806)	NC score	0.419650 (rank : 174)
Query Neighborhood Hits	808	Target Neighborhood Hits	276	Shared Neighborhood Hits	244
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

VDR_HUMAN
θ value	8.99809 (rank : 807)	NC score	-0.003645 (rank : 1126)
Query Neighborhood Hits	808	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_MOUSE
θ value	8.99809 (rank : 808)	NC score	-0.003677 (rank : 1127)
Query Neighborhood Hits	808	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

ADA10_HUMAN
θ value	θ > 10 (rank : 809)	NC score	0.149360 (rank : 459)
Query Neighborhood Hits	808	Target Neighborhood Hits	189	Shared Neighborhood Hits	150
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 810)	NC score	0.146765 (rank : 461)
Query Neighborhood Hits	808	Target Neighborhood Hits	194	Shared Neighborhood Hits	150
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA18_HUMAN
θ value	θ > 10 (rank : 811)	NC score	0.135569 (rank : 484)
Query Neighborhood Hits	808	Target Neighborhood Hits	184	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA29_HUMAN
θ value	θ > 10 (rank : 812)	NC score	0.118335 (rank : 540)
Query Neighborhood Hits	808	Target Neighborhood Hits	247	Shared Neighborhood Hits	144
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADAM2_MOUSE
θ value	θ > 10 (rank : 813)	NC score	0.143342 (rank : 466)
Query Neighborhood Hits	808	Target Neighborhood Hits	209	Shared Neighborhood Hits	165
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADEC1_HUMAN
θ value	θ > 10 (rank : 814)	NC score	0.064931 (rank : 768)
Query Neighborhood Hits	808	Target Neighborhood Hits	80	Shared Neighborhood Hits	48
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	θ > 10 (rank : 815)	NC score	0.066579 (rank : 752)
Query Neighborhood Hits	808	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ALEX_HUMAN
θ value	θ > 10 (rank : 816)	NC score	0.051705 (rank : 916)
Query Neighborhood Hits	808	Target Neighborhood Hits	361	Shared Neighborhood Hits	48
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ANR38_MOUSE
θ value	θ > 10 (rank : 817)	NC score	0.050049 (rank : 939)
Query Neighborhood Hits	808	Target Neighborhood Hits	512	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

APR3_HUMAN
θ value	θ > 10 (rank : 818)	NC score	0.108934 (rank : 564)
Query Neighborhood Hits	808	Target Neighborhood Hits	50	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

APR3_MOUSE
θ value	θ > 10 (rank : 819)	NC score	0.111598 (rank : 559)
Query Neighborhood Hits	808	Target Neighborhood Hits	61	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ASTN_HUMAN
θ value	θ > 10 (rank : 820)	NC score	0.130114 (rank : 501)
Query Neighborhood Hits	808	Target Neighborhood Hits	105	Shared Neighborhood Hits	82
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 821)	NC score	0.126279 (rank : 513)
Query Neighborhood Hits	808	Target Neighborhood Hits	98	Shared Neighborhood Hits	78
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATL2_HUMAN
θ value	θ > 10 (rank : 822)	NC score	0.056887 (rank : 859)
Query Neighborhood Hits	808	Target Neighborhood Hits	125	Shared Neighborhood Hits	58
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
θ value	θ > 10 (rank : 823)	NC score	0.052756 (rank : 899)
Query Neighborhood Hits	808	Target Neighborhood Hits	137	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATS12_HUMAN
θ value	θ > 10 (rank : 824)	NC score	0.072448 (rank : 710)
Query Neighborhood Hits	808	Target Neighborhood Hits	251	Shared Neighborhood Hits	116
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_MOUSE
θ value	θ > 10 (rank : 825)	NC score	0.067198 (rank : 746)
Query Neighborhood Hits	808	Target Neighborhood Hits	220	Shared Neighborhood Hits	110
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS13_MOUSE
θ value	θ > 10 (rank : 826)	NC score	0.065924 (rank : 760)
Query Neighborhood Hits	808	Target Neighborhood Hits	227	Shared Neighborhood Hits	108
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS15_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.057846 (rank : 854)
Query Neighborhood Hits	808	Target Neighborhood Hits	151	Shared Neighborhood Hits	80
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS17_HUMAN
θ value	θ > 10 (rank : 828)	NC score	0.066021 (rank : 759)
Query Neighborhood Hits	808	Target Neighborhood Hits	194	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS18_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.070292 (rank : 729)
Query Neighborhood Hits	808	Target Neighborhood Hits	169	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_MOUSE
θ value	θ > 10 (rank : 830)	NC score	0.064014 (rank : 776)
Query Neighborhood Hits	808	Target Neighborhood Hits	163	Shared Neighborhood Hits	88
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS19_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.058662 (rank : 842)
Query Neighborhood Hits	808	Target Neighborhood Hits	203	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS19_MOUSE
θ value	θ > 10 (rank : 832)	NC score	0.060111 (rank : 826)
Query Neighborhood Hits	808	Target Neighborhood Hits	188	Shared Neighborhood Hits	87
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS20_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.077234 (rank : 683)
Query Neighborhood Hits	808	Target Neighborhood Hits	192	Shared Neighborhood Hits	107
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_MOUSE
θ value	θ > 10 (rank : 834)	NC score	0.080184 (rank : 667)
Query Neighborhood Hits	808	Target Neighborhood Hits	225	Shared Neighborhood Hits	122
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS2_MOUSE
θ value	θ > 10 (rank : 835)	NC score	0.054413 (rank : 876)
Query Neighborhood Hits	808	Target Neighborhood Hits	179	Shared Neighborhood Hits	80
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS3_HUMAN
θ value	θ > 10 (rank : 836)	NC score	0.060141 (rank : 825)
Query Neighborhood Hits	808	Target Neighborhood Hits	179	Shared Neighborhood Hits	89
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS4_HUMAN
θ value	θ > 10 (rank : 837)	NC score	0.053359 (rank : 893)
Query Neighborhood Hits	808	Target Neighborhood Hits	138	Shared Neighborhood Hits	69
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS4_MOUSE
θ value	θ > 10 (rank : 838)	NC score	0.056615 (rank : 861)
Query Neighborhood Hits	808	Target Neighborhood Hits	145	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS5_HUMAN
θ value	θ > 10 (rank : 839)	NC score	0.055585 (rank : 871)
Query Neighborhood Hits	808	Target Neighborhood Hits	141	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS5_MOUSE
θ value	θ > 10 (rank : 840)	NC score	0.059243 (rank : 835)
Query Neighborhood Hits	808	Target Neighborhood Hits	147	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS6_HUMAN
θ value	θ > 10 (rank : 841)	NC score	0.062412 (rank : 798)
Query Neighborhood Hits	808	Target Neighborhood Hits	141	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS8_MOUSE
θ value	θ > 10 (rank : 842)	NC score	0.057219 (rank : 857)
Query Neighborhood Hits	808	Target Neighborhood Hits	139	Shared Neighborhood Hits	68
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

BAI1_HUMAN
θ value	θ > 10 (rank : 843)	NC score	0.102299 (rank : 593)
Query Neighborhood Hits	808	Target Neighborhood Hits	375	Shared Neighborhood Hits	102
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	θ > 10 (rank : 844)	NC score	0.098308 (rank : 605)
Query Neighborhood Hits	808	Target Neighborhood Hits	340	Shared Neighborhood Hits	97
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
θ value	θ > 10 (rank : 845)	NC score	0.088527 (rank : 640)
Query Neighborhood Hits	808	Target Neighborhood Hits	332	Shared Neighborhood Hits	79
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	θ > 10 (rank : 846)	NC score	0.090421 (rank : 634)
Query Neighborhood Hits	808	Target Neighborhood Hits	323	Shared Neighborhood Hits	83
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BASP_MOUSE
θ value	θ > 10 (rank : 847)	NC score	0.053257 (rank : 895)
Query Neighborhood Hits	808	Target Neighborhood Hits	260	Shared Neighborhood Hits	32
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BSN_MOUSE
θ value	θ > 10 (rank : 848)	NC score	0.062528 (rank : 796)
Query Neighborhood Hits	808	Target Neighborhood Hits	2057	Shared Neighborhood Hits	136
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BTC_MOUSE
θ value	θ > 10 (rank : 849)	NC score	0.062248 (rank : 800)
Query Neighborhood Hits	808	Target Neighborhood Hits	67	Shared Neighborhood Hits	45
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

C1RA_MOUSE
θ value	θ > 10 (rank : 850)	NC score	0.125585 (rank : 518)
Query Neighborhood Hits	808	Target Neighborhood Hits	379	Shared Neighborhood Hits	154
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 851)	NC score	0.124010 (rank : 523)
Query Neighborhood Hits	808	Target Neighborhood Hits	380	Shared Neighborhood Hits	154
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 852)	NC score	0.113680 (rank : 548)
Query Neighborhood Hits	808	Target Neighborhood Hits	364	Shared Neighborhood Hits	147
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 853)	NC score	0.100580 (rank : 597)
Query Neighborhood Hits	808	Target Neighborhood Hits	359	Shared Neighborhood Hits	145
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CD248_HUMAN
θ value	θ > 10 (rank : 854)	NC score	0.420359 (rank : 172)
Query Neighborhood Hits	808	Target Neighborhood Hits	679	Shared Neighborhood Hits	265
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 855)	NC score	0.410551 (rank : 187)
Query Neighborhood Hits	808	Target Neighborhood Hits	578	Shared Neighborhood Hits	247
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD2A1_MOUSE
θ value	θ > 10 (rank : 856)	NC score	0.053551 (rank : 890)
Query Neighborhood Hits	808	Target Neighborhood Hits	206	Shared Neighborhood Hits	11
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CD320_HUMAN
θ value	θ > 10 (rank : 857)	NC score	0.192804 (rank : 364)
Query Neighborhood Hits	808	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CDN2B_HUMAN
θ value	θ > 10 (rank : 858)	NC score	0.053943 (rank : 881)
Query Neighborhood Hits	808	Target Neighborhood Hits	196	Shared Neighborhood Hits	11
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CFAB_MOUSE
θ value	θ > 10 (rank : 859)	NC score	0.052267 (rank : 904)
Query Neighborhood Hits	808	Target Neighborhood Hits	262	Shared Neighborhood Hits	56
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAI_MOUSE
θ value	θ > 10 (rank : 860)	NC score	0.074907 (rank : 702)
Query Neighborhood Hits	808	Target Neighborhood Hits	290	Shared Neighborhood Hits	79
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFC1_MOUSE
θ value	θ > 10 (rank : 861)	NC score	0.250650 (rank : 295)
Query Neighborhood Hits	808	Target Neighborhood Hits	125	Shared Neighborhood Hits	108
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CI094_HUMAN
θ value	θ > 10 (rank : 862)	NC score	0.051009 (rank : 925)
Query Neighborhood Hits	808	Target Neighborhood Hits	310	Shared Neighborhood Hits	49
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CIC_MOUSE
θ value	θ > 10 (rank : 863)	NC score	0.052243 (rank : 905)
Query Neighborhood Hits	808	Target Neighborhood Hits	742	Shared Neighborhood Hits	86
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CILP1_HUMAN
θ value	θ > 10 (rank : 864)	NC score	0.053666 (rank : 887)
Query Neighborhood Hits	808	Target Neighborhood Hits	266	Shared Neighborhood Hits	50
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_MOUSE
θ value	θ > 10 (rank : 865)	NC score	0.053601 (rank : 889)
Query Neighborhood Hits	808	Target Neighborhood Hits	282	Shared Neighborhood Hits	47
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP2_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.056278 (rank : 863)
Query Neighborhood Hits	808	Target Neighborhood Hits	307	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CK024_HUMAN
θ value	θ > 10 (rank : 867)	NC score	0.126593 (rank : 511)
Query Neighborhood Hits	808	Target Neighborhood Hits	408	Shared Neighborhood Hits	67
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CLC14_HUMAN
θ value	θ > 10 (rank : 868)	NC score	0.166504 (rank : 425)
Query Neighborhood Hits	808	Target Neighborhood Hits	143	Shared Neighborhood Hits	98
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 869)	NC score	0.178924 (rank : 399)
Query Neighborhood Hits	808	Target Neighborhood Hits	120	Shared Neighborhood Hits	95
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CN155_HUMAN
θ value	θ > 10 (rank : 870)	NC score	0.091281 (rank : 631)
Query Neighborhood Hits	808	Target Neighborhood Hits	385	Shared Neighborhood Hits	66
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CO1A1_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.066181 (rank : 756)
Query Neighborhood Hits	808	Target Neighborhood Hits	475	Shared Neighborhood Hits	86
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_HUMAN
θ value	θ > 10 (rank : 872)	NC score	0.059329 (rank : 832)
Query Neighborhood Hits	808	Target Neighborhood Hits	452	Shared Neighborhood Hits	69
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO3A1_MOUSE
θ value	θ > 10 (rank : 873)	NC score	0.061058 (rank : 814)
Query Neighborhood Hits	808	Target Neighborhood Hits	466	Shared Neighborhood Hits	66
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO6A3_HUMAN
θ value	θ > 10 (rank : 874)	NC score	0.058445 (rank : 846)
Query Neighborhood Hits	808	Target Neighborhood Hits	317	Shared Neighborhood Hits	50
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

CO7A1_HUMAN
θ value	θ > 10 (rank : 875)	NC score	0.068376 (rank : 742)
Query Neighborhood Hits	808	Target Neighborhood Hits	807	Shared Neighborhood Hits	96
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO7_HUMAN
θ value	θ > 10 (rank : 876)	NC score	0.171843 (rank : 412)
Query Neighborhood Hits	808	Target Neighborhood Hits	278	Shared Neighborhood Hits	160
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_MOUSE
θ value	θ > 10 (rank : 877)	NC score	0.121983 (rank : 531)
Query Neighborhood Hits	808	Target Neighborhood Hits	182	Shared Neighborhood Hits	101
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	θ > 10 (rank : 878)	NC score	0.125859 (rank : 515)
Query Neighborhood Hits	808	Target Neighborhood Hits	199	Shared Neighborhood Hits	106
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 879)	NC score	0.152079 (rank : 457)
Query Neighborhood Hits	808	Target Neighborhood Hits	224	Shared Neighborhood Hits	132
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO9_HUMAN
θ value	θ > 10 (rank : 880)	NC score	0.125677 (rank : 517)
Query Neighborhood Hits	808	Target Neighborhood Hits	147	Shared Neighborhood Hits	89
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 881)	NC score	0.129674 (rank : 503)
Query Neighborhood Hits	808	Target Neighborhood Hits	153	Shared Neighborhood Hits	95
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

COCA1_HUMAN
θ value	θ > 10 (rank : 882)	NC score	0.077728 (rank : 682)
Query Neighborhood Hits	808	Target Neighborhood Hits	458	Shared Neighborhood Hits	70
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 883)	NC score	0.081309 (rank : 661)
Query Neighborhood Hits	808	Target Neighborhood Hits	467	Shared Neighborhood Hits	72
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCH_HUMAN
θ value	θ > 10 (rank : 884)	NC score	0.051895 (rank : 912)
Query Neighborhood Hits	808	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

COCH_MOUSE
θ value	θ > 10 (rank : 885)	NC score	0.051746 (rank : 915)
Query Neighborhood Hits	808	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

COEA1_HUMAN
θ value	θ > 10 (rank : 886)	NC score	0.071248 (rank : 723)
Query Neighborhood Hits	808	Target Neighborhood Hits	427	Shared Neighborhood Hits	61
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 887)	NC score	0.072338 (rank : 712)
Query Neighborhood Hits	808	Target Neighborhood Hits	402	Shared Neighborhood Hits	62
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COKA1_HUMAN
θ value	θ > 10 (rank : 888)	NC score	0.078197 (rank : 678)
Query Neighborhood Hits	808	Target Neighborhood Hits	403	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CP003_HUMAN
θ value	θ > 10 (rank : 889)	NC score	0.066535 (rank : 753)
Query Neighborhood Hits	808	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

CR001_HUMAN
θ value	θ > 10 (rank : 890)	NC score	0.069270 (rank : 737)
Query Neighborhood Hits	808	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CR001_MOUSE
θ value	θ > 10 (rank : 891)	NC score	0.067841 (rank : 745)
Query Neighborhood Hits	808	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

CR2_HUMAN
θ value	θ > 10 (rank : 892)	NC score	0.055655 (rank : 868)
Query Neighborhood Hits	808	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

CRAC1_HUMAN
θ value	θ > 10 (rank : 893)	NC score	0.214780 (rank : 327)
Query Neighborhood Hits	808	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 894)	NC score	0.216412 (rank : 324)
Query Neighborhood Hits	808	Target Neighborhood Hits	112	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CS016_HUMAN
θ value	θ > 10 (rank : 895)	NC score	0.051595 (rank : 917)
Query Neighborhood Hits	808	Target Neighborhood Hits	310	Shared Neighborhood Hits	59
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

CS1A_MOUSE
θ value	θ > 10 (rank : 896)	NC score	0.103401 (rank : 585)
Query Neighborhood Hits	808	Target Neighborhood Hits	360	Shared Neighborhood Hits	143
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 897)	NC score	0.103192 (rank : 587)
Query Neighborhood Hits	808	Target Neighborhood Hits	361	Shared Neighborhood Hits	141
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CSKI1_HUMAN
θ value	θ > 10 (rank : 898)	NC score	0.053893 (rank : 882)
Query Neighborhood Hits	808	Target Neighborhood Hits	997	Shared Neighborhood Hits	84
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	θ > 10 (rank : 899)	NC score	0.058094 (rank : 850)
Query Neighborhood Hits	808	Target Neighborhood Hits	1031	Shared Neighborhood Hits	93
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 900)	NC score	0.090902 (rank : 633)
Query Neighborhood Hits	808	Target Neighborhood Hits	188	Shared Neighborhood Hits	68
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSPG4_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.072475 (rank : 709)
Query Neighborhood Hits	808	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 902)	NC score	0.073449 (rank : 705)
Query Neighborhood Hits	808	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CUZD1_HUMAN
θ value	θ > 10 (rank : 903)	NC score	0.095691 (rank : 615)
Query Neighborhood Hits	808	Target Neighborhood Hits	89	Shared Neighborhood Hits	29
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 904)	NC score	0.093071 (rank : 628)
Query Neighborhood Hits	808	Target Neighborhood Hits	91	Shared Neighborhood Hits	31
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DAF1_MOUSE
θ value	θ > 10 (rank : 905)	NC score	0.063242 (rank : 789)
Query Neighborhood Hits	808	Target Neighborhood Hits	204	Shared Neighborhood Hits	47
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DAG1_HUMAN
θ value	θ > 10 (rank : 906)	NC score	0.052158 (rank : 906)
Query Neighborhood Hits	808	Target Neighborhood Hits	104	Shared Neighborhood Hits	38
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

DCBD1_HUMAN
θ value	θ > 10 (rank : 907)	NC score	0.068846 (rank : 741)
Query Neighborhood Hits	808	Target Neighborhood Hits	110	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 908)	NC score	0.064400 (rank : 773)
Query Neighborhood Hits	808	Target Neighborhood Hits	118	Shared Neighborhood Hits	39
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 909)	NC score	0.064925 (rank : 769)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DKK3_HUMAN
θ value	θ > 10 (rank : 910)	NC score	0.077085 (rank : 684)
Query Neighborhood Hits	808	Target Neighborhood Hits	74	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
θ value	θ > 10 (rank : 911)	NC score	0.086991 (rank : 644)
Query Neighborhood Hits	808	Target Neighborhood Hits	83	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

DMBT1_HUMAN
θ value	θ > 10 (rank : 912)	NC score	0.066672 (rank : 751)
Query Neighborhood Hits	808	Target Neighborhood Hits	152	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	θ > 10 (rank : 913)	NC score	0.071583 (rank : 718)
Query Neighborhood Hits	808	Target Neighborhood Hits	134	Shared Neighborhood Hits	34
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

ECM2_HUMAN
θ value	θ > 10 (rank : 914)	NC score	0.053490 (rank : 891)
Query Neighborhood Hits	808	Target Neighborhood Hits	402	Shared Neighborhood Hits	58
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

EGFL7_MOUSE
θ value	θ > 10 (rank : 915)	NC score	0.446259 (rank : 151)
Query Neighborhood Hits	808	Target Neighborhood Hits	287	Shared Neighborhood Hits	245
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 916)	NC score	0.426501 (rank : 162)
Query Neighborhood Hits	808	Target Neighborhood Hits	270	Shared Neighborhood Hits	219
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 917)	NC score	0.421338 (rank : 170)
Query Neighborhood Hits	808	Target Neighborhood Hits	266	Shared Neighborhood Hits	224
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EMR3_HUMAN
θ value	θ > 10 (rank : 918)	NC score	0.208303 (rank : 337)
Query Neighborhood Hits	808	Target Neighborhood Hits	245	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 919)	NC score	0.157038 (rank : 447)
Query Neighborhood Hits	808	Target Neighborhood Hits	191	Shared Neighborhood Hits	109
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

EPGN_HUMAN
θ value	θ > 10 (rank : 920)	NC score	0.061132 (rank : 813)
Query Neighborhood Hits	808	Target Neighborhood Hits	59	Shared Neighborhood Hits	40
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EPGN_MOUSE
θ value	θ > 10 (rank : 921)	NC score	0.070001 (rank : 731)
Query Neighborhood Hits	808	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EREG_HUMAN
θ value	θ > 10 (rank : 922)	NC score	0.087906 (rank : 642)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	52
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

EREG_MOUSE
θ value	θ > 10 (rank : 923)	NC score	0.051495 (rank : 920)
Query Neighborhood Hits	808	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

FA47A_HUMAN
θ value	θ > 10 (rank : 924)	NC score	0.057938 (rank : 852)
Query Neighborhood Hits	808	Target Neighborhood Hits	451	Shared Neighborhood Hits	40
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FREM1_HUMAN
θ value	θ > 10 (rank : 925)	NC score	0.058771 (rank : 840)
Query Neighborhood Hits	808	Target Neighborhood Hits	170	Shared Neighborhood Hits	18
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM1_MOUSE
θ value	θ > 10 (rank : 926)	NC score	0.054373 (rank : 878)
Query Neighborhood Hits	808	Target Neighborhood Hits	163	Shared Neighborhood Hits	15
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM2_HUMAN
θ value	θ > 10 (rank : 927)	NC score	0.057432 (rank : 855)
Query Neighborhood Hits	808	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FREM2_MOUSE
θ value	θ > 10 (rank : 928)	NC score	0.058879 (rank : 838)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

FREM3_HUMAN
θ value	θ > 10 (rank : 929)	NC score	0.050510 (rank : 929)
Query Neighborhood Hits	808	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

FREM3_MOUSE
θ value	θ > 10 (rank : 930)	NC score	0.050229 (rank : 934)
Query Neighborhood Hits	808	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

GGN_HUMAN
θ value	θ > 10 (rank : 931)	NC score	0.055505 (rank : 872)
Query Neighborhood Hits	808	Target Neighborhood Hits	269	Shared Neighborhood Hits	42
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 932)	NC score	0.060381 (rank : 822)
Query Neighborhood Hits	808	Target Neighborhood Hits	311	Shared Neighborhood Hits	54
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GLU2B_HUMAN
θ value	θ > 10 (rank : 933)	NC score	0.081410 (rank : 660)
Query Neighborhood Hits	808	Target Neighborhood Hits	377	Shared Neighborhood Hits	59
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GLU2B_MOUSE
θ value	θ > 10 (rank : 934)	NC score	0.070642 (rank : 727)
Query Neighborhood Hits	808	Target Neighborhood Hits	357	Shared Neighborhood Hits	49
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GNPTA_HUMAN
θ value	θ > 10 (rank : 935)	NC score	0.071206 (rank : 724)
Query Neighborhood Hits	808	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GNPTA_MOUSE
θ value	θ > 10 (rank : 936)	NC score	0.069913 (rank : 732)
Query Neighborhood Hits	808	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GP113_HUMAN
θ value	θ > 10 (rank : 937)	NC score	0.058621 (rank : 843)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP114_HUMAN
θ value	θ > 10 (rank : 938)	NC score	0.052882 (rank : 898)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP116_HUMAN
θ value	θ > 10 (rank : 939)	NC score	0.053110 (rank : 896)
Query Neighborhood Hits	808	Target Neighborhood Hits	167	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP126_HUMAN
θ value	θ > 10 (rank : 940)	NC score	0.075862 (rank : 696)
Query Neighborhood Hits	808	Target Neighborhood Hits	187	Shared Neighborhood Hits	44
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP128_HUMAN
θ value	θ > 10 (rank : 941)	NC score	0.063809 (rank : 780)
Query Neighborhood Hits	808	Target Neighborhood Hits	135	Shared Neighborhood Hits	49
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP128_MOUSE
θ value	θ > 10 (rank : 942)	NC score	0.068076 (rank : 744)
Query Neighborhood Hits	808	Target Neighborhood Hits	141	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP133_HUMAN
θ value	θ > 10 (rank : 943)	NC score	0.050981 (rank : 926)
Query Neighborhood Hits	808	Target Neighborhood Hits	115	Shared Neighborhood Hits	18
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP144_HUMAN
θ value	θ > 10 (rank : 944)	NC score	0.051850 (rank : 914)
Query Neighborhood Hits	808	Target Neighborhood Hits	108	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GP2_HUMAN
θ value	θ > 10 (rank : 945)	NC score	0.116751 (rank : 543)
Query Neighborhood Hits	808	Target Neighborhood Hits	34	Shared Neighborhood Hits	13
SwissProt Accessions	P55259, Q13338, Q9UIF1	Gene names	GP2
Domain Architecture
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2) (ZAP75).

GP2_MOUSE
θ value	θ > 10 (rank : 946)	NC score	0.111664 (rank : 558)
Query Neighborhood Hits	808	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D733	Gene names	Gp2
Domain Architecture	No domain graphic available
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2).

GPR64_HUMAN
θ value	θ > 10 (rank : 947)	NC score	0.060448 (rank : 819)
Query Neighborhood Hits	808	Target Neighborhood Hits	207	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GPR64_MOUSE
θ value	θ > 10 (rank : 948)	NC score	0.059560 (rank : 831)
Query Neighborhood Hits	808	Target Neighborhood Hits	156	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR98_HUMAN
θ value	θ > 10 (rank : 949)	NC score	0.053867 (rank : 884)
Query Neighborhood Hits	808	Target Neighborhood Hits	202	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GPR98_MOUSE
θ value	θ > 10 (rank : 950)	NC score	0.058321 (rank : 847)
Query Neighborhood Hits	808	Target Neighborhood Hits	206	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

GRIN1_MOUSE
θ value	θ > 10 (rank : 951)	NC score	0.056200 (rank : 864)
Query Neighborhood Hits	808	Target Neighborhood Hits	337	Shared Neighborhood Hits	49
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

GSCR1_HUMAN
θ value	θ > 10 (rank : 952)	NC score	0.081632 (rank : 658)
Query Neighborhood Hits	808	Target Neighborhood Hits	674	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HBEGF_HUMAN
θ value	θ > 10 (rank : 953)	NC score	0.053636 (rank : 888)
Query Neighborhood Hits	808	Target Neighborhood Hits	61	Shared Neighborhood Hits	41
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

HHIP_MOUSE
θ value	θ > 10 (rank : 954)	NC score	0.351943 (rank : 236)
Query Neighborhood Hits	808	Target Neighborhood Hits	219	Shared Neighborhood Hits	192
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HPLN1_HUMAN
θ value	θ > 10 (rank : 955)	NC score	0.059632 (rank : 830)
Query Neighborhood Hits	808	Target Neighborhood Hits	67	Shared Neighborhood Hits	15
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN1_MOUSE
θ value	θ > 10 (rank : 956)	NC score	0.059679 (rank : 829)
Query Neighborhood Hits	808	Target Neighborhood Hits	64	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN2_HUMAN
θ value	θ > 10 (rank : 957)	NC score	0.061328 (rank : 812)
Query Neighborhood Hits	808	Target Neighborhood Hits	80	Shared Neighborhood Hits	17
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN2_MOUSE
θ value	θ > 10 (rank : 958)	NC score	0.061699 (rank : 806)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN3_HUMAN
θ value	θ > 10 (rank : 959)	NC score	0.060334 (rank : 823)
Query Neighborhood Hits	808	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

HPLN3_MOUSE
θ value	θ > 10 (rank : 960)	NC score	0.061576 (rank : 808)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

HPLN4_HUMAN
θ value	θ > 10 (rank : 961)	NC score	0.059254 (rank : 834)
Query Neighborhood Hits	808	Target Neighborhood Hits	100	Shared Neighborhood Hits	17
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

HPLN4_MOUSE
θ value	θ > 10 (rank : 962)	NC score	0.059297 (rank : 833)
Query Neighborhood Hits	808	Target Neighborhood Hits	98	Shared Neighborhood Hits	17
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

IDD_HUMAN
θ value	θ > 10 (rank : 963)	NC score	0.108322 (rank : 566)
Query Neighborhood Hits	808	Target Neighborhood Hits	127	Shared Neighborhood Hits	57
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

IDD_MOUSE
θ value	θ > 10 (rank : 964)	NC score	0.098511 (rank : 603)
Query Neighborhood Hits	808	Target Neighborhood Hits	151	Shared Neighborhood Hits	59
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

ITB7_MOUSE
θ value	θ > 10 (rank : 965)	NC score	0.326912 (rank : 257)
Query Neighborhood Hits	808	Target Neighborhood Hits	277	Shared Neighborhood Hits	240
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

K1683_HUMAN
θ value	θ > 10 (rank : 966)	NC score	0.071496 (rank : 720)
Query Neighborhood Hits	808	Target Neighborhood Hits	240	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

KI67_HUMAN
θ value	θ > 10 (rank : 967)	NC score	0.065143 (rank : 766)
Query Neighborhood Hits	808	Target Neighborhood Hits	581	Shared Neighborhood Hits	47
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

KR111_HUMAN
θ value	θ > 10 (rank : 968)	NC score	0.182225 (rank : 391)
Query Neighborhood Hits	808	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

KR124_HUMAN
θ value	θ > 10 (rank : 969)	NC score	0.218601 (rank : 321)
Query Neighborhood Hits	808	Target Neighborhood Hits	124	Shared Neighborhood Hits	103
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR131_HUMAN
θ value	θ > 10 (rank : 970)	NC score	0.123914 (rank : 524)
Query Neighborhood Hits	808	Target Neighborhood Hits	123	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

KR132_HUMAN
θ value	θ > 10 (rank : 971)	NC score	0.097857 (rank : 606)
Query Neighborhood Hits	808	Target Neighborhood Hits	69	Shared Neighborhood Hits	55
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

KR133_HUMAN
θ value	θ > 10 (rank : 972)	NC score	0.095046 (rank : 618)
Query Neighborhood Hits	808	Target Neighborhood Hits	66	Shared Neighborhood Hits	58
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

KR134_HUMAN
θ value	θ > 10 (rank : 973)	NC score	0.107127 (rank : 573)
Query Neighborhood Hits	808	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

KR221_HUMAN
θ value	θ > 10 (rank : 974)	NC score	0.057225 (rank : 856)
Query Neighborhood Hits	808	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.

KRA32_HUMAN
θ value	θ > 10 (rank : 975)	NC score	0.067189 (rank : 747)
Query Neighborhood Hits	808	Target Neighborhood Hits	51	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYR7	Gene names	KRTAP3-2, KAP3.2, KRTAP3.2
Domain Architecture
Description	Keratin-associated protein 3-2 (Keratin-associated protein 3.2) (High sulfur keratin-associated protein 3.2).

KRA33_HUMAN
θ value	θ > 10 (rank : 976)	NC score	0.060805 (rank : 818)
Query Neighborhood Hits	808	Target Neighborhood Hits	53	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BYR6, Q52LP0	Gene names	KRTAP3-3, KAP3.3, KRTAP3.3
Domain Architecture
Description	Keratin-associated protein 3-3 (Keratin-associated protein 3.3) (High sulfur keratin-associated protein 3.3).

LAD1_HUMAN
θ value	θ > 10 (rank : 977)	NC score	0.065709 (rank : 761)
Query Neighborhood Hits	808	Target Neighborhood Hits	441	Shared Neighborhood Hits	42
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LAMA4_HUMAN
θ value	θ > 10 (rank : 978)	NC score	0.294222 (rank : 270)
Query Neighborhood Hits	808	Target Neighborhood Hits	708	Shared Neighborhood Hits	224
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LEUK_MOUSE
θ value	θ > 10 (rank : 979)	NC score	0.066146 (rank : 758)
Query Neighborhood Hits	808	Target Neighborhood Hits	147	Shared Neighborhood Hits	31
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

LORI_MOUSE
θ value	θ > 10 (rank : 980)	NC score	0.111049 (rank : 560)
Query Neighborhood Hits	808	Target Neighborhood Hits	47	Shared Neighborhood Hits	22
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LPHN1_HUMAN
θ value	θ > 10 (rank : 981)	NC score	0.051980 (rank : 910)
Query Neighborhood Hits	808	Target Neighborhood Hits	155	Shared Neighborhood Hits	29
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
θ value	θ > 10 (rank : 982)	NC score	0.051130 (rank : 924)
Query Neighborhood Hits	808	Target Neighborhood Hits	136	Shared Neighborhood Hits	24
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LPHN3_HUMAN
θ value	θ > 10 (rank : 983)	NC score	0.050080 (rank : 937)
Query Neighborhood Hits	808	Target Neighborhood Hits	139	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LRP10_HUMAN
θ value	θ > 10 (rank : 984)	NC score	0.167113 (rank : 423)
Query Neighborhood Hits	808	Target Neighborhood Hits	197	Shared Neighborhood Hits	105
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP11_HUMAN
θ value	θ > 10 (rank : 985)	NC score	0.076965 (rank : 686)
Query Neighborhood Hits	808	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP11_MOUSE
θ value	θ > 10 (rank : 986)	NC score	0.081632 (rank : 659)
Query Neighborhood Hits	808	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 987)	NC score	0.166047 (rank : 426)
Query Neighborhood Hits	808	Target Neighborhood Hits	205	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 988)	NC score	0.163651 (rank : 432)
Query Neighborhood Hits	808	Target Neighborhood Hits	180	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP5_HUMAN
θ value	θ > 10 (rank : 989)	NC score	0.243352 (rank : 304)
Query Neighborhood Hits	808	Target Neighborhood Hits	224	Shared Neighborhood Hits	144
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

MARCS_HUMAN
θ value	θ > 10 (rank : 990)	NC score	0.050117 (rank : 936)
Query Neighborhood Hits	808	Target Neighborhood Hits	204	Shared Neighborhood Hits	30
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MASP1_HUMAN
θ value	θ > 10 (rank : 991)	NC score	0.101606 (rank : 594)
Query Neighborhood Hits	808	Target Neighborhood Hits	369	Shared Neighborhood Hits	143
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 992)	NC score	0.098846 (rank : 602)
Query Neighborhood Hits	808	Target Neighborhood Hits	364	Shared Neighborhood Hits	141
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 993)	NC score	0.109410 (rank : 563)
Query Neighborhood Hits	808	Target Neighborhood Hits	364	Shared Neighborhood Hits	144
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 994)	NC score	0.107980 (rank : 568)
Query Neighborhood Hits	808	Target Neighborhood Hits	382	Shared Neighborhood Hits	150
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MATN1_HUMAN
θ value	θ > 10 (rank : 995)	NC score	0.179776 (rank : 395)
Query Neighborhood Hits	808	Target Neighborhood Hits	191	Shared Neighborhood Hits	118
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 996)	NC score	0.179702 (rank : 396)
Query Neighborhood Hits	808	Target Neighborhood Hits	186	Shared Neighborhood Hits	116
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MBD6_HUMAN
θ value	θ > 10 (rank : 997)	NC score	0.065101 (rank : 767)
Query Neighborhood Hits	808	Target Neighborhood Hits	349	Shared Neighborhood Hits	53
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MCSP_HUMAN
θ value	θ > 10 (rank : 998)	NC score	0.071806 (rank : 715)
Query Neighborhood Hits	808	Target Neighborhood Hits	48	Shared Neighborhood Hits	31
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEP1B_MOUSE
θ value	θ > 10 (rank : 999)	NC score	0.125242 (rank : 520)
Query Neighborhood Hits	808	Target Neighborhood Hits	127	Shared Neighborhood Hits	95
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MFRP_HUMAN
θ value	θ > 10 (rank : 1000)	NC score	0.106917 (rank : 574)
Query Neighborhood Hits	808	Target Neighborhood Hits	165	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 1001)	NC score	0.091905 (rank : 630)
Query Neighborhood Hits	808	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MT1H_HUMAN
θ value	θ > 10 (rank : 1002)	NC score	0.108820 (rank : 565)
Query Neighborhood Hits	808	Target Neighborhood Hits	78	Shared Neighborhood Hits	69
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT3_HUMAN
θ value	θ > 10 (rank : 1003)	NC score	0.170521 (rank : 417)
Query Neighborhood Hits	808	Target Neighborhood Hits	82	Shared Neighborhood Hits	67
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 1004)	NC score	0.159429 (rank : 441)
Query Neighborhood Hits	808	Target Neighborhood Hits	68	Shared Neighborhood Hits	58
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MUC13_HUMAN
θ value	θ > 10 (rank : 1005)	NC score	0.144497 (rank : 464)
Query Neighborhood Hits	808	Target Neighborhood Hits	164	Shared Neighborhood Hits	115
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MUC1_MOUSE
θ value	θ > 10 (rank : 1006)	NC score	0.120179 (rank : 536)
Query Neighborhood Hits	808	Target Neighborhood Hits	388	Shared Neighborhood Hits	72
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC7_HUMAN
θ value	θ > 10 (rank : 1007)	NC score	0.125391 (rank : 519)
Query Neighborhood Hits	808	Target Neighborhood Hits	538	Shared Neighborhood Hits	100
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MUCDL_HUMAN
θ value	θ > 10 (rank : 1008)	NC score	0.063943 (rank : 777)
Query Neighborhood Hits	808	Target Neighborhood Hits	777	Shared Neighborhood Hits	78
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MUCDL_MOUSE
θ value	θ > 10 (rank : 1009)	NC score	0.055476 (rank : 873)
Query Neighborhood Hits	808	Target Neighborhood Hits	461	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NCOA6_HUMAN
θ value	θ > 10 (rank : 1010)	NC score	0.060954 (rank : 816)
Query Neighborhood Hits	808	Target Neighborhood Hits	1202	Shared Neighborhood Hits	107
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	θ > 10 (rank : 1011)	NC score	0.072650 (rank : 707)
Query Neighborhood Hits	808	Target Neighborhood Hits	1076	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NET1_HUMAN
θ value	θ > 10 (rank : 1012)	NC score	0.212206 (rank : 331)
Query Neighborhood Hits	808	Target Neighborhood Hits	149	Shared Neighborhood Hits	116
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	θ > 10 (rank : 1013)	NC score	0.207292 (rank : 341)
Query Neighborhood Hits	808	Target Neighborhood Hits	151	Shared Neighborhood Hits	114
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NETO1_HUMAN
θ value	θ > 10 (rank : 1014)	NC score	0.075895 (rank : 695)
Query Neighborhood Hits	808	Target Neighborhood Hits	110	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 1015)	NC score	0.076099 (rank : 694)
Query Neighborhood Hits	808	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 1016)	NC score	0.078324 (rank : 677)
Query Neighborhood Hits	808	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 1017)	NC score	0.078044 (rank : 679)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NEU1_MOUSE
θ value	θ > 10 (rank : 1018)	NC score	0.065427 (rank : 763)
Query Neighborhood Hits	808	Target Neighborhood Hits	64	Shared Neighborhood Hits	53
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

NFRKB_HUMAN
θ value	θ > 10 (rank : 1019)	NC score	0.060186 (rank : 824)
Query Neighborhood Hits	808	Target Neighborhood Hits	211	Shared Neighborhood Hits	45
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NFRKB_MOUSE
θ value	θ > 10 (rank : 1020)	NC score	0.061409 (rank : 811)
Query Neighborhood Hits	808	Target Neighborhood Hits	393	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NOLC1_HUMAN
θ value	θ > 10 (rank : 1021)	NC score	0.054466 (rank : 874)
Query Neighborhood Hits	808	Target Neighborhood Hits	452	Shared Neighborhood Hits	46
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NRG2_HUMAN
θ value	θ > 10 (rank : 1022)	NC score	0.103116 (rank : 588)
Query Neighborhood Hits	808	Target Neighborhood Hits	419	Shared Neighborhood Hits	113
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 1023)	NC score	0.121980 (rank : 532)
Query Neighborhood Hits	808	Target Neighborhood Hits	392	Shared Neighborhood Hits	121
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG3_HUMAN
θ value	θ > 10 (rank : 1024)	NC score	0.068925 (rank : 740)
Query Neighborhood Hits	808	Target Neighborhood Hits	119	Shared Neighborhood Hits	67
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG3_MOUSE
θ value	θ > 10 (rank : 1025)	NC score	0.076296 (rank : 691)
Query Neighborhood Hits	808	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG4_HUMAN
θ value	θ > 10 (rank : 1026)	NC score	0.136554 (rank : 480)
Query Neighborhood Hits	808	Target Neighborhood Hits	85	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 1027)	NC score	0.121578 (rank : 533)
Query Neighborhood Hits	808	Target Neighborhood Hits	79	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NTNG1_HUMAN
θ value	θ > 10 (rank : 1028)	NC score	0.320485 (rank : 264)
Query Neighborhood Hits	808	Target Neighborhood Hits	247	Shared Neighborhood Hits	203
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 1029)	NC score	0.317269 (rank : 267)
Query Neighborhood Hits	808	Target Neighborhood Hits	246	Shared Neighborhood Hits	199
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_MOUSE
θ value	θ > 10 (rank : 1030)	NC score	0.353786 (rank : 232)
Query Neighborhood Hits	808	Target Neighborhood Hits	276	Shared Neighborhood Hits	232
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NU214_HUMAN
θ value	θ > 10 (rank : 1031)	NC score	0.080623 (rank : 664)
Query Neighborhood Hits	808	Target Neighborhood Hits	657	Shared Neighborhood Hits	78
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NUP62_MOUSE
θ value	θ > 10 (rank : 1032)	NC score	0.053867 (rank : 885)
Query Neighborhood Hits	808	Target Neighborhood Hits	200	Shared Neighborhood Hits	30
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

PAP2_HUMAN
θ value	θ > 10 (rank : 1033)	NC score	0.080228 (rank : 666)
Query Neighborhood Hits	808	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PARM1_MOUSE
θ value	θ > 10 (rank : 1034)	NC score	0.069767 (rank : 733)
Query Neighborhood Hits	808	Target Neighborhood Hits	140	Shared Neighborhood Hits	35
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PCLO_MOUSE
θ value	θ > 10 (rank : 1035)	NC score	0.056563 (rank : 862)
Query Neighborhood Hits	808	Target Neighborhood Hits	2275	Shared Neighborhood Hits	153
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PCOC1_HUMAN
θ value	θ > 10 (rank : 1036)	NC score	0.062233 (rank : 801)
Query Neighborhood Hits	808	Target Neighborhood Hits	146	Shared Neighborhood Hits	30
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 1037)	NC score	0.064342 (rank : 775)
Query Neighborhood Hits	808	Target Neighborhood Hits	100	Shared Neighborhood Hits	33
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 1038)	NC score	0.061531 (rank : 810)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 1039)	NC score	0.062017 (rank : 805)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 1040)	NC score	0.053472 (rank : 892)
Query Neighborhood Hits	808	Target Neighborhood Hits	74	Shared Neighborhood Hits	26
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 1041)	NC score	0.050538 (rank : 927)
Query Neighborhood Hits	808	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PERT_HUMAN
θ value	θ > 10 (rank : 1042)	NC score	0.208568 (rank : 336)
Query Neighborhood Hits	808	Target Neighborhood Hits	221	Shared Neighborhood Hits	151
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 1043)	NC score	0.195015 (rank : 363)
Query Neighborhood Hits	808	Target Neighborhood Hits	221	Shared Neighborhood Hits	145
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGH1_HUMAN
θ value	θ > 10 (rank : 1044)	NC score	0.108093 (rank : 567)
Query Neighborhood Hits	808	Target Neighborhood Hits	91	Shared Neighborhood Hits	72
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PHXR5_MOUSE
θ value	θ > 10 (rank : 1045)	NC score	0.153700 (rank : 453)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	70
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PO121_HUMAN
θ value	θ > 10 (rank : 1046)	NC score	0.076166 (rank : 693)
Query Neighborhood Hits	808	Target Neighborhood Hits	344	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	θ > 10 (rank : 1047)	NC score	0.063026 (rank : 794)
Query Neighborhood Hits	808	Target Neighborhood Hits	345	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PODXL_MOUSE
θ value	θ > 10 (rank : 1048)	NC score	0.065560 (rank : 762)
Query Neighborhood Hits	808	Target Neighborhood Hits	130	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R0M4, Q9ESZ1	Gene names	Podxl, Pclp1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PRG4_HUMAN
θ value	θ > 10 (rank : 1049)	NC score	0.120612 (rank : 534)
Query Neighborhood Hits	808	Target Neighborhood Hits	764	Shared Neighborhood Hits	132
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PROC_HUMAN
θ value	θ > 10 (rank : 1050)	NC score	0.171092 (rank : 415)
Query Neighborhood Hits	808	Target Neighborhood Hits	406	Shared Neighborhood Hits	227
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROP_HUMAN
θ value	θ > 10 (rank : 1051)	NC score	0.084122 (rank : 651)
Query Neighborhood Hits	808	Target Neighborhood Hits	126	Shared Neighborhood Hits	52
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	θ > 10 (rank : 1052)	NC score	0.097061 (rank : 609)
Query Neighborhood Hits	808	Target Neighborhood Hits	165	Shared Neighborhood Hits	70
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PRP1_HUMAN
θ value	θ > 10 (rank : 1053)	NC score	0.051918 (rank : 911)
Query Neighborhood Hits	808	Target Neighborhood Hits	385	Shared Neighborhood Hits	41
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 1054)	NC score	0.076856 (rank : 688)
Query Neighborhood Hits	808	Target Neighborhood Hits	347	Shared Neighborhood Hits	43
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR12_HUMAN
θ value	θ > 10 (rank : 1055)	NC score	0.063208 (rank : 792)
Query Neighborhood Hits	808	Target Neighborhood Hits	460	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PTPRB_HUMAN
θ value	θ > 10 (rank : 1056)	NC score	0.051229 (rank : 921)
Query Neighborhood Hits	808	Target Neighborhood Hits	242	Shared Neighborhood Hits	36
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRS_HUMAN
θ value	θ > 10 (rank : 1057)	NC score	0.050466 (rank : 930)
Query Neighborhood Hits	808	Target Neighborhood Hits	472	Shared Neighborhood Hits	60
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

RAPH1_HUMAN
θ value	θ > 10 (rank : 1058)	NC score	0.063003 (rank : 795)
Query Neighborhood Hits	808	Target Neighborhood Hits	593	Shared Neighborhood Hits	70
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RERE_HUMAN
θ value	θ > 10 (rank : 1059)	NC score	0.051212 (rank : 923)
Query Neighborhood Hits	808	Target Neighborhood Hits	779	Shared Neighborhood Hits	90
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 1060)	NC score	0.052662 (rank : 901)
Query Neighborhood Hits	808	Target Neighborhood Hits	785	Shared Neighborhood Hits	82
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RPB1_HUMAN
θ value	θ > 10 (rank : 1061)	NC score	0.058946 (rank : 837)
Query Neighborhood Hits	808	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	θ > 10 (rank : 1062)	NC score	0.058470 (rank : 845)
Query Neighborhood Hits	808	Target Neighborhood Hits	363	Shared Neighborhood Hits	49
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RSPO1_MOUSE
θ value	θ > 10 (rank : 1063)	NC score	0.075642 (rank : 697)
Query Neighborhood Hits	808	Target Neighborhood Hits	85	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO2_HUMAN
θ value	θ > 10 (rank : 1064)	NC score	0.097129 (rank : 608)
Query Neighborhood Hits	808	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
θ value	θ > 10 (rank : 1065)	NC score	0.097699 (rank : 607)
Query Neighborhood Hits	808	Target Neighborhood Hits	88	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO3_MOUSE
θ value	θ > 10 (rank : 1066)	NC score	0.123580 (rank : 525)
Query Neighborhood Hits	808	Target Neighborhood Hits	120	Shared Neighborhood Hits	79
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_MOUSE
θ value	θ > 10 (rank : 1067)	NC score	0.107558 (rank : 569)
Query Neighborhood Hits	808	Target Neighborhood Hits	110	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SDC3_HUMAN
θ value	θ > 10 (rank : 1068)	NC score	0.089079 (rank : 639)
Query Neighborhood Hits	808	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

SDC3_MOUSE
θ value	θ > 10 (rank : 1069)	NC score	0.076195 (rank : 692)
Query Neighborhood Hits	808	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SELPL_HUMAN
θ value	θ > 10 (rank : 1070)	NC score	0.066981 (rank : 748)
Query Neighborhood Hits	808	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

SELV_HUMAN
θ value	θ > 10 (rank : 1071)	NC score	0.054422 (rank : 875)
Query Neighborhood Hits	808	Target Neighborhood Hits	118	Shared Neighborhood Hits	29
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SEM5B_MOUSE
θ value	θ > 10 (rank : 1072)	NC score	0.063438 (rank : 784)
Query Neighborhood Hits	808	Target Neighborhood Hits	190	Shared Neighborhood Hits	74
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEZ6L_HUMAN
θ value	θ > 10 (rank : 1073)	NC score	0.076918 (rank : 687)
Query Neighborhood Hits	808	Target Neighborhood Hits	289	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SF3A2_MOUSE
θ value	θ > 10 (rank : 1074)	NC score	0.056049 (rank : 866)
Query Neighborhood Hits	808	Target Neighborhood Hits	247	Shared Neighborhood Hits	41
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SHAN1_HUMAN
θ value	θ > 10 (rank : 1075)	NC score	0.064356 (rank : 774)
Query Neighborhood Hits	808	Target Neighborhood Hits	1041	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SHBG_HUMAN
θ value	θ > 10 (rank : 1076)	NC score	0.074054 (rank : 703)
Query Neighborhood Hits	808	Target Neighborhood Hits	45	Shared Neighborhood Hits	34
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SHBG_MOUSE
θ value	θ > 10 (rank : 1077)	NC score	0.069586 (rank : 734)
Query Neighborhood Hits	808	Target Neighborhood Hits	50	Shared Neighborhood Hits	39
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SMDF_HUMAN
θ value	θ > 10 (rank : 1078)	NC score	0.133053 (rank : 488)
Query Neighborhood Hits	808	Target Neighborhood Hits	117	Shared Neighborhood Hits	70
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SPIT1_HUMAN
θ value	θ > 10 (rank : 1079)	NC score	0.080820 (rank : 663)
Query Neighborhood Hits	808	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPON1_HUMAN
θ value	θ > 10 (rank : 1080)	NC score	0.071562 (rank : 719)
Query Neighborhood Hits	808	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	θ > 10 (rank : 1081)	NC score	0.073909 (rank : 704)
Query Neighborhood Hits	808	Target Neighborhood Hits	123	Shared Neighborhood Hits	58
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPRR3_HUMAN
θ value	θ > 10 (rank : 1082)	NC score	0.050051 (rank : 938)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SRPX_HUMAN
θ value	θ > 10 (rank : 1083)	NC score	0.058860 (rank : 839)
Query Neighborhood Hits	808	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

SRPX_MOUSE
θ value	θ > 10 (rank : 1084)	NC score	0.062215 (rank : 803)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

SRRM1_HUMAN
θ value	θ > 10 (rank : 1085)	NC score	0.061600 (rank : 807)
Query Neighborhood Hits	808	Target Neighborhood Hits	690	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 1086)	NC score	0.071204 (rank : 725)
Query Neighborhood Hits	808	Target Neighborhood Hits	966	Shared Neighborhood Hits	83
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 1087)	NC score	0.056054 (rank : 865)
Query Neighborhood Hits	808	Target Neighborhood Hits	1296	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 1088)	NC score	0.063337 (rank : 787)
Query Neighborhood Hits	808	Target Neighborhood Hits	1470	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TAF4_HUMAN
θ value	θ > 10 (rank : 1089)	NC score	0.063340 (rank : 786)
Query Neighborhood Hits	808	Target Neighborhood Hits	687	Shared Neighborhood Hits	62
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TAU_HUMAN
θ value	θ > 10 (rank : 1090)	NC score	0.063871 (rank : 779)
Query Neighborhood Hits	808	Target Neighborhood Hits	448	Shared Neighborhood Hits	56
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TCOF_HUMAN
θ value	θ > 10 (rank : 1091)	NC score	0.059905 (rank : 828)
Query Neighborhood Hits	808	Target Neighborhood Hits	543	Shared Neighborhood Hits	62
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 1092)	NC score	0.064747 (rank : 771)
Query Neighborhood Hits	808	Target Neighborhood Hits	471	Shared Neighborhood Hits	52
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TDGF1_HUMAN
θ value	θ > 10 (rank : 1093)	NC score	0.210991 (rank : 334)
Query Neighborhood Hits	808	Target Neighborhood Hits	132	Shared Neighborhood Hits	110
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 1094)	NC score	0.253511 (rank : 289)
Query Neighborhood Hits	808	Target Neighborhood Hits	146	Shared Neighborhood Hits	125
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 1095)	NC score	0.207304 (rank : 340)
Query Neighborhood Hits	808	Target Neighborhood Hits	131	Shared Neighborhood Hits	106
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TECTB_HUMAN
θ value	θ > 10 (rank : 1096)	NC score	0.075504 (rank : 699)
Query Neighborhood Hits	808	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PL2	Gene names	TECTB
Domain Architecture
Description	Beta-tectorin precursor.

TECTB_MOUSE
θ value	θ > 10 (rank : 1097)	NC score	0.077913 (rank : 680)
Query Neighborhood Hits	808	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	O08524	Gene names	Tectb
Domain Architecture
Description	Beta-tectorin precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 1098)	NC score	0.222337 (rank : 318)
Query Neighborhood Hits	808	Target Neighborhood Hits	211	Shared Neighborhood Hits	140
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 1099)	NC score	0.224395 (rank : 317)
Query Neighborhood Hits	808	Target Neighborhood Hits	214	Shared Neighborhood Hits	142
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TGFA_HUMAN
θ value	θ > 10 (rank : 1100)	NC score	0.052093 (rank : 908)
Query Neighborhood Hits	808	Target Neighborhood Hits	61	Shared Neighborhood Hits	42
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TM108_HUMAN
θ value	θ > 10 (rank : 1101)	NC score	0.063359 (rank : 785)
Query Neighborhood Hits	808	Target Neighborhood Hits	166	Shared Neighborhood Hits	35
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TMPS6_HUMAN
θ value	θ > 10 (rank : 1102)	NC score	0.107508 (rank : 571)
Query Neighborhood Hits	808	Target Neighborhood Hits	338	Shared Neighborhood Hits	138
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 1103)	NC score	0.102737 (rank : 592)
Query Neighborhood Hits	808	Target Neighborhood Hits	341	Shared Neighborhood Hits	140
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_HUMAN
θ value	θ > 10 (rank : 1104)	NC score	0.079377 (rank : 671)
Query Neighborhood Hits	808	Target Neighborhood Hits	275	Shared Neighborhood Hits	85
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TNR11_HUMAN
θ value	θ > 10 (rank : 1105)	NC score	0.111034 (rank : 561)
Query Neighborhood Hits	808	Target Neighborhood Hits	135	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR16_MOUSE
θ value	θ > 10 (rank : 1106)	NC score	0.175592 (rank : 405)
Query Neighborhood Hits	808	Target Neighborhood Hits	178	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR18_HUMAN
θ value	θ > 10 (rank : 1107)	NC score	0.069221 (rank : 739)
Query Neighborhood Hits	808	Target Neighborhood Hits	55	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR19_HUMAN
θ value	θ > 10 (rank : 1108)	NC score	0.071797 (rank : 716)
Query Neighborhood Hits	808	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 1109)	NC score	0.066884 (rank : 749)
Query Neighborhood Hits	808	Target Neighborhood Hits	100	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR1B_HUMAN
θ value	θ > 10 (rank : 1110)	NC score	0.093921 (rank : 624)
Query Neighborhood Hits	808	Target Neighborhood Hits	127	Shared Neighborhood Hits	78
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR23_MOUSE
θ value	θ > 10 (rank : 1111)	NC score	0.120368 (rank : 535)
Query Neighborhood Hits	808	Target Neighborhood Hits	114	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR26_MOUSE
θ value	θ > 10 (rank : 1112)	NC score	0.114195 (rank : 545)
Query Neighborhood Hits	808	Target Neighborhood Hits	106	Shared Neighborhood Hits	82
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR4_HUMAN
θ value	θ > 10 (rank : 1113)	NC score	0.117111 (rank : 541)
Query Neighborhood Hits	808	Target Neighborhood Hits	152	Shared Neighborhood Hits	93
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR4_MOUSE
θ value	θ > 10 (rank : 1114)	NC score	0.123107 (rank : 527)
Query Neighborhood Hits	808	Target Neighborhood Hits	137	Shared Neighborhood Hits	90
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR5_HUMAN
θ value	θ > 10 (rank : 1115)	NC score	0.087932 (rank : 641)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR5_MOUSE
θ value	θ > 10 (rank : 1116)	NC score	0.113102 (rank : 552)
Query Neighborhood Hits	808	Target Neighborhood Hits	131	Shared Neighborhood Hits	91
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR6_HUMAN
θ value	θ > 10 (rank : 1117)	NC score	0.082044 (rank : 657)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	63
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
θ value	θ > 10 (rank : 1118)	NC score	0.095048 (rank : 617)
Query Neighborhood Hits	808	Target Neighborhood Hits	99	Shared Neighborhood Hits	70
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TPA_HUMAN
θ value	θ > 10 (rank : 1119)	NC score	0.099875 (rank : 599)
Query Neighborhood Hits	808	Target Neighborhood Hits	324	Shared Neighborhood Hits	142
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TR10B_HUMAN
θ value	θ > 10 (rank : 1120)	NC score	0.066207 (rank : 755)
Query Neighborhood Hits	808	Target Neighborhood Hits	71	Shared Neighborhood Hits	46
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10B_MOUSE
θ value	θ > 10 (rank : 1121)	NC score	0.070007 (rank : 730)
Query Neighborhood Hits	808	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR19L_HUMAN
θ value	θ > 10 (rank : 1122)	NC score	0.050515 (rank : 928)
Query Neighborhood Hits	808	Target Neighborhood Hits	99	Shared Neighborhood Hits	46
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR19L_MOUSE
θ value	θ > 10 (rank : 1123)	NC score	0.051544 (rank : 919)
Query Neighborhood Hits	808	Target Neighborhood Hits	85	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TSG6_HUMAN
θ value	θ > 10 (rank : 1124)	NC score	0.094111 (rank : 623)
Query Neighborhood Hits	808	Target Neighborhood Hits	91	Shared Neighborhood Hits	37
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 1125)	NC score	0.094899 (rank : 620)
Query Neighborhood Hits	808	Target Neighborhood Hits	91	Shared Neighborhood Hits	36
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSP3_HUMAN
θ value	θ > 10 (rank : 1126)	NC score	0.379295 (rank : 213)
Query Neighborhood Hits	808	Target Neighborhood Hits	250	Shared Neighborhood Hits	210
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

UROK_HUMAN
θ value	θ > 10 (rank : 1127)	NC score	0.058476 (rank : 844)
Query Neighborhood Hits	808	Target Neighborhood Hits	272	Shared Neighborhood Hits	97
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROK_MOUSE
θ value	θ > 10 (rank : 1128)	NC score	0.059120 (rank : 836)
Query Neighborhood Hits	808	Target Neighborhood Hits	273	Shared Neighborhood Hits	101
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROL1_HUMAN
θ value	θ > 10 (rank : 1129)	NC score	0.221551 (rank : 320)
Query Neighborhood Hits	808	Target Neighborhood Hits	213	Shared Neighborhood Hits	132
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 1130)	NC score	0.240449 (rank : 308)
Query Neighborhood Hits	808	Target Neighborhood Hits	235	Shared Neighborhood Hits	145
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

VASN_HUMAN
θ value	θ > 10 (rank : 1131)	NC score	0.093236 (rank : 627)
Query Neighborhood Hits	808	Target Neighborhood Hits	449	Shared Neighborhood Hits	138
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VITRN_MOUSE
θ value	θ > 10 (rank : 1132)	NC score	0.051224 (rank : 922)
Query Neighborhood Hits	808	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

WASIP_HUMAN
θ value	θ > 10 (rank : 1133)	NC score	0.058136 (rank : 849)
Query Neighborhood Hits	808	Target Neighborhood Hits	458	Shared Neighborhood Hits	56
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 1134)	NC score	0.062251 (rank : 799)
Query Neighborhood Hits	808	Target Neighborhood Hits	392	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ZN207_HUMAN
θ value	θ > 10 (rank : 1135)	NC score	0.077794 (rank : 681)
Query Neighborhood Hits	808	Target Neighborhood Hits	326	Shared Neighborhood Hits	47
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZP2_HUMAN
θ value	θ > 10 (rank : 1136)	NC score	0.055610 (rank : 869)
Query Neighborhood Hits	808	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q05996	Gene names	ZP2, ZPA
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

ZP2_MOUSE
θ value	θ > 10 (rank : 1137)	NC score	0.053891 (rank : 883)
Query Neighborhood Hits	808	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	P20239	Gene names	Zp2, Zp-2, Zpa
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

ZP4_HUMAN
θ value	θ > 10 (rank : 1138)	NC score	0.064566 (rank : 772)
Query Neighborhood Hits	808	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

Hits sorted by NC score

ZAN_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	808	Target Neighborhood Hits	808	Shared Neighborhood Hits	808
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZAN_HUMAN
NC score	0.801019 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	808	Target Neighborhood Hits	679	Shared Neighborhood Hits	427
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

MUC5B_HUMAN
NC score	0.715387 (rank : 3)	θ value	2.23575e-83 (rank : 5)
Query Neighborhood Hits	808	Target Neighborhood Hits	1020	Shared Neighborhood Hits	415
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MEGF6_HUMAN
NC score	0.672076 (rank : 4)	θ value	1.0531e-32 (rank : 17)
Query Neighborhood Hits	808	Target Neighborhood Hits	671	Shared Neighborhood Hits	475
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

FBN2_MOUSE
NC score	0.650662 (rank : 5)	θ value	5.39604e-37 (rank : 14)
Query Neighborhood Hits	808	Target Neighborhood Hits	549	Shared Neighborhood Hits	420
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_HUMAN
NC score	0.650606 (rank : 6)	θ value	3.06405e-32 (rank : 19)
Query Neighborhood Hits	808	Target Neighborhood Hits	560	Shared Neighborhood Hits	412
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

SSPO_MOUSE
NC score	0.650209 (rank : 7)	θ value	3.69378e-78 (rank : 7)
Query Neighborhood Hits	808	Target Neighborhood Hits	800	Shared Neighborhood Hits	452
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

VWF_HUMAN
NC score	0.649651 (rank : 8)	θ value	2.17053e-70 (rank : 9)
Query Neighborhood Hits	808	Target Neighborhood Hits	396	Shared Neighborhood Hits	280
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

JAG1_HUMAN
NC score	0.649632 (rank : 9)	θ value	1.24977e-17 (rank : 32)
Query Neighborhood Hits	808	Target Neighborhood Hits	514	Shared Neighborhood Hits	399
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

NELL1_HUMAN
NC score	0.649584 (rank : 10)	θ value	4.15078e-21 (rank : 29)
Query Neighborhood Hits	808	Target Neighborhood Hits	451	Shared Neighborhood Hits	359
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

FBN1_HUMAN
NC score	0.648107 (rank : 11)	θ value	1.08726e-37 (rank : 13)
Query Neighborhood Hits	808	Target Neighborhood Hits	557	Shared Neighborhood Hits	406
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

JAG1_MOUSE
NC score	0.647749 (rank : 12)	θ value	1.38178e-16 (rank : 34)
Query Neighborhood Hits	808	Target Neighborhood Hits	518	Shared Neighborhood Hits	396
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

FBN1_MOUSE
NC score	0.647533 (rank : 13)	θ value	4.41421e-39 (rank : 12)
Query Neighborhood Hits	808	Target Neighborhood Hits	563	Shared Neighborhood Hits	407
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

SREC_HUMAN
NC score	0.644003 (rank : 14)	θ value	2.20605e-14 (rank : 44)
Query Neighborhood Hits	808	Target Neighborhood Hits	645	Shared Neighborhood Hits	432
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

BMPER_MOUSE
NC score	0.642600 (rank : 15)	θ value	8.87376e-48 (rank : 10)
Query Neighborhood Hits	808	Target Neighborhood Hits	194	Shared Neighborhood Hits	169
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

FBN3_HUMAN
NC score	0.642197 (rank : 16)	θ value	6.61148e-27 (rank : 25)
Query Neighborhood Hits	808	Target Neighborhood Hits	543	Shared Neighborhood Hits	395
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

KR107_HUMAN
NC score	0.640927 (rank : 17)	θ value	2.28291e-11 (rank : 61)
Query Neighborhood Hits	808	Target Neighborhood Hits	330	Shared Neighborhood Hits	275
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR104_HUMAN
NC score	0.640817 (rank : 18)	θ value	1.74796e-11 (rank : 59)
Query Neighborhood Hits	808	Target Neighborhood Hits	313	Shared Neighborhood Hits	257
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

JAG2_HUMAN
NC score	0.640119 (rank : 19)	θ value	4.02038e-16 (rank : 37)
Query Neighborhood Hits	808	Target Neighborhood Hits	491	Shared Neighborhood Hits	387
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
NC score	0.634097 (rank : 20)	θ value	3.76295e-14 (rank : 45)
Query Neighborhood Hits	808	Target Neighborhood Hits	504	Shared Neighborhood Hits	393
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR106_HUMAN
NC score	0.633140 (rank : 21)	θ value	7.34386e-10 (rank : 71)
Query Neighborhood Hits	808	Target Neighborhood Hits	347	Shared Neighborhood Hits	285
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

NELL2_HUMAN
NC score	0.632859 (rank : 22)	θ value	1.38178e-16 (rank : 35)
Query Neighborhood Hits	808	Target Neighborhood Hits	449	Shared Neighborhood Hits	350
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
NC score	0.632044 (rank : 23)	θ value	7.09661e-13 (rank : 51)
Query Neighborhood Hits	808	Target Neighborhood Hits	436	Shared Neighborhood Hits	347
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

VWF_MOUSE
NC score	0.630246 (rank : 24)	θ value	1.65806e-78 (rank : 6)
Query Neighborhood Hits	808	Target Neighborhood Hits	381	Shared Neighborhood Hits	277
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

NOTC1_MOUSE
NC score	0.629426 (rank : 25)	θ value	5.77852e-31 (rank : 23)
Query Neighborhood Hits	808	Target Neighborhood Hits	916	Shared Neighborhood Hits	435
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

BMPER_HUMAN
NC score	0.625438 (rank : 26)	θ value	5.7518e-47 (rank : 11)
Query Neighborhood Hits	808	Target Neighborhood Hits	175	Shared Neighborhood Hits	151
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CRIM1_HUMAN
NC score	0.618361 (rank : 27)	θ value	1.13037e-18 (rank : 31)
Query Neighborhood Hits	808	Target Neighborhood Hits	362	Shared Neighborhood Hits	291
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

MUC2_HUMAN
NC score	0.617896 (rank : 28)	θ value	7.45998e-71 (rank : 8)
Query Neighborhood Hits	808	Target Neighborhood Hits	906	Shared Neighborhood Hits	303
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

LTBP2_HUMAN
NC score	0.617095 (rank : 29)	θ value	2.20605e-14 (rank : 43)
Query Neighborhood Hits	808	Target Neighborhood Hits	552	Shared Neighborhood Hits	380
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP4_MOUSE
NC score	0.615490 (rank : 30)	θ value	1.58096e-12 (rank : 53)
Query Neighborhood Hits	808	Target Neighborhood Hits	607	Shared Neighborhood Hits	365
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

SREC2_MOUSE
NC score	0.614785 (rank : 31)	θ value	1.02475e-11 (rank : 58)
Query Neighborhood Hits	808	Target Neighborhood Hits	605	Shared Neighborhood Hits	403
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TECTA_MOUSE
NC score	0.614464 (rank : 32)	θ value	2.04937e-153 (rank : 4)
Query Neighborhood Hits	808	Target Neighborhood Hits	244	Shared Neighborhood Hits	206
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

NOTC1_HUMAN
NC score	0.613190 (rank : 33)	θ value	1.24399e-33 (rank : 15)
Query Neighborhood Hits	808	Target Neighborhood Hits	906	Shared Neighborhood Hits	420
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SREC2_HUMAN
NC score	0.612081 (rank : 34)	θ value	8.67504e-11 (rank : 63)
Query Neighborhood Hits	808	Target Neighborhood Hits	645	Shared Neighborhood Hits	401
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LTBP2_MOUSE
NC score	0.611060 (rank : 35)	θ value	7.84624e-12 (rank : 57)
Query Neighborhood Hits	808	Target Neighborhood Hits	617	Shared Neighborhood Hits	382
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NOTC3_HUMAN
NC score	0.608812 (rank : 36)	θ value	2.59387e-31 (rank : 20)
Query Neighborhood Hits	808	Target Neighborhood Hits	1062	Shared Neighborhood Hits	465
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
NC score	0.608175 (rank : 37)	θ value	3.3877e-31 (rank : 22)
Query Neighborhood Hits	808	Target Neighborhood Hits	975	Shared Neighborhood Hits	454
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TECTA_HUMAN
NC score	0.606324 (rank : 38)	θ value	4.12933e-154 (rank : 3)
Query Neighborhood Hits	808	Target Neighborhood Hits	239	Shared Neighborhood Hits	199
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

NOTC2_MOUSE
NC score	0.604650 (rank : 39)	θ value	1.24399e-33 (rank : 16)
Query Neighborhood Hits	808	Target Neighborhood Hits	1069	Shared Neighborhood Hits	435
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DLL1_MOUSE
NC score	0.602991 (rank : 40)	θ value	2.13673e-09 (rank : 73)
Query Neighborhood Hits	808	Target Neighborhood Hits	456	Shared Neighborhood Hits	373
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

NOTC2_HUMAN
NC score	0.602169 (rank : 41)	θ value	3.07116e-24 (rank : 27)
Query Neighborhood Hits	808	Target Neighborhood Hits	1113	Shared Neighborhood Hits	460
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KRA53_HUMAN
NC score	0.600815 (rank : 42)	θ value	1.53129e-07 (rank : 105)
Query Neighborhood Hits	808	Target Neighborhood Hits	331	Shared Neighborhood Hits	274
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

CRUM1_HUMAN
NC score	0.594730 (rank : 43)	θ value	6.87365e-08 (rank : 97)
Query Neighborhood Hits	808	Target Neighborhood Hits	457	Shared Neighborhood Hits	353
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

NOTC4_HUMAN
NC score	0.592799 (rank : 44)	θ value	3.39556e-23 (rank : 28)
Query Neighborhood Hits	808	Target Neighborhood Hits	905	Shared Neighborhood Hits	435
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

DLL4_MOUSE
NC score	0.592188 (rank : 45)	θ value	4.76016e-09 (rank : 77)
Query Neighborhood Hits	808	Target Neighborhood Hits	440	Shared Neighborhood Hits	360
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

CRUM2_HUMAN
NC score	0.591710 (rank : 46)	θ value	9.92553e-07 (rank : 120)
Query Neighborhood Hits	808	Target Neighborhood Hits	453	Shared Neighborhood Hits	350
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

DLL1_HUMAN
NC score	0.590870 (rank : 47)	θ value	1.29631e-06 (rank : 122)
Query Neighborhood Hits	808	Target Neighborhood Hits	455	Shared Neighborhood Hits	371
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

CRUM1_MOUSE
NC score	0.589827 (rank : 48)	θ value	1.69304e-06 (rank : 126)
Query Neighborhood Hits	808	Target Neighborhood Hits	444	Shared Neighborhood Hits	350
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

LTBP3_HUMAN
NC score	0.589442 (rank : 49)	θ value	1.74796e-11 (rank : 60)
Query Neighborhood Hits	808	Target Neighborhood Hits	502	Shared Neighborhood Hits	358
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

DLL4_HUMAN
NC score	0.588977 (rank : 50)	θ value	1.80886e-08 (rank : 85)
Query Neighborhood Hits	808	Target Neighborhood Hits	435	Shared Neighborhood Hits	350
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NOTC4_MOUSE
NC score	0.588582 (rank : 51)	θ value	5.97985e-28 (rank : 24)
Query Neighborhood Hits	808	Target Neighborhood Hits	872	Shared Neighborhood Hits	432
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

DNER_HUMAN
NC score	0.587799 (rank : 52)	θ value	5.44631e-05 (rank : 167)
Query Neighborhood Hits	808	Target Neighborhood Hits	460	Shared Neighborhood Hits	357
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

LTB1L_HUMAN
NC score	0.585209 (rank : 53)	θ value	6.21693e-09 (rank : 81)
Query Neighborhood Hits	808	Target Neighborhood Hits	553	Shared Neighborhood Hits	360
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_MOUSE
NC score	0.583795 (rank : 54)	θ value	6.87365e-08 (rank : 99)
Query Neighborhood Hits	808	Target Neighborhood Hits	475	Shared Neighborhood Hits	351
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTB1L_MOUSE
NC score	0.583000 (rank : 55)	θ value	1.47974e-10 (rank : 64)
Query Neighborhood Hits	808	Target Neighborhood Hits	514	Shared Neighborhood Hits	357
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.582772 (rank : 56)	θ value	6.21693e-09 (rank : 82)
Query Neighborhood Hits	808	Target Neighborhood Hits	502	Shared Neighborhood Hits	341
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.582352 (rank : 57)	θ value	1.47974e-10 (rank : 65)
Query Neighborhood Hits	808	Target Neighborhood Hits	479	Shared Neighborhood Hits	338
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBLN2_MOUSE
NC score	0.581448 (rank : 58)	θ value	4.59992e-12 (rank : 54)
Query Neighborhood Hits	808	Target Neighborhood Hits	505	Shared Neighborhood Hits	316
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

DLK_HUMAN
NC score	0.580309 (rank : 59)	θ value	7.1131e-05 (rank : 171)
Query Neighborhood Hits	808	Target Neighborhood Hits	401	Shared Neighborhood Hits	342
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DNER_MOUSE
NC score	0.577946 (rank : 60)	θ value	4.1701e-05 (rank : 163)
Query Neighborhood Hits	808	Target Neighborhood Hits	413	Shared Neighborhood Hits	333
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

FBLN2_HUMAN
NC score	0.576097 (rank : 61)	θ value	1.9326e-10 (rank : 67)
Query Neighborhood Hits	808	Target Neighborhood Hits	392	Shared Neighborhood Hits	282
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

KRA58_HUMAN
NC score	0.575008 (rank : 62)	θ value	0.000121331 (rank : 180)
Query Neighborhood Hits	808	Target Neighborhood Hits	324	Shared Neighborhood Hits	261
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

DLK_MOUSE
NC score	0.574652 (rank : 63)	θ value	4.1701e-05 (rank : 162)
Query Neighborhood Hits	808	Target Neighborhood Hits	374	Shared Neighborhood Hits	327
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

STAB1_MOUSE
NC score	0.574193 (rank : 64)	θ value	1.80886e-08 (rank : 87)
Query Neighborhood Hits	808	Target Neighborhood Hits	566	Shared Neighborhood Hits	413
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

DLL3_HUMAN
NC score	0.571793 (rank : 65)	θ value	0.000121331 (rank : 178)
Query Neighborhood Hits	808	Target Neighborhood Hits	419	Shared Neighborhood Hits	340
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

SCUB3_MOUSE
NC score	0.566060 (rank : 66)	θ value	5.08577e-11 (rank : 62)
Query Neighborhood Hits	808	Target Neighborhood Hits	442	Shared Neighborhood Hits	313
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.564398 (rank : 67)	θ value	4.16044e-13 (rank : 50)
Query Neighborhood Hits	808	Target Neighborhood Hits	428	Shared Neighborhood Hits	307
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

DLL3_MOUSE
NC score	0.563904 (rank : 68)	θ value	1.17247e-07 (rank : 102)
Query Neighborhood Hits	808	Target Neighborhood Hits	399	Shared Neighborhood Hits	322
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

EGFL9_HUMAN
NC score	0.561218 (rank : 69)	θ value	9.29e-05 (rank : 175)
Query Neighborhood Hits	808	Target Neighborhood Hits	365	Shared Neighborhood Hits	312
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

STAB1_HUMAN
NC score	0.560839 (rank : 70)	θ value	3.41135e-07 (rank : 112)
Query Neighborhood Hits	808	Target Neighborhood Hits	546	Shared Neighborhood Hits	394
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB2_MOUSE
NC score	0.559665 (rank : 71)	θ value	1.99992e-07 (rank : 108)
Query Neighborhood Hits	808	Target Neighborhood Hits	528	Shared Neighborhood Hits	388
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

EGFL9_MOUSE
NC score	0.559534 (rank : 72)	θ value	0.0148317 (rank : 306)
Query Neighborhood Hits	808	Target Neighborhood Hits	379	Shared Neighborhood Hits	319
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

WIF1_HUMAN
NC score	0.557473 (rank : 73)	θ value	0.00390308 (rank : 267)
Query Neighborhood Hits	808	Target Neighborhood Hits	392	Shared Neighborhood Hits	340
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
NC score	0.555377 (rank : 74)	θ value	0.0148317 (rank : 312)
Query Neighborhood Hits	808	Target Neighborhood Hits	393	Shared Neighborhood Hits	335
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

STAB2_HUMAN
NC score	0.554305 (rank : 75)	θ value	5.81887e-07 (rank : 116)
Query Neighborhood Hits	808	Target Neighborhood Hits	534	Shared Neighborhood Hits	386
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

FBLN1_MOUSE
NC score	0.550577 (rank : 76)	θ value	1.53129e-07 (rank : 104)
Query Neighborhood Hits	808	Target Neighborhood Hits	329	Shared Neighborhood Hits	269
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

KR101_HUMAN
NC score	0.550562 (rank : 77)	θ value	3.08544e-08 (rank : 88)
Query Neighborhood Hits	808	Target Neighborhood Hits	261	Shared Neighborhood Hits	216
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

FBLN1_HUMAN
NC score	0.549240 (rank : 78)	θ value	8.40245e-06 (rank : 143)
Query Neighborhood Hits	808	Target Neighborhood Hits	324	Shared Neighborhood Hits	270
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

KRA51_HUMAN
NC score	0.546665 (rank : 79)	θ value	2.88788e-06 (rank : 129)
Query Neighborhood Hits	808	Target Neighborhood Hits	288	Shared Neighborhood Hits	223
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

TRBM_HUMAN
NC score	0.546454 (rank : 80)	θ value	3.77169e-06 (rank : 136)
Query Neighborhood Hits	808	Target Neighborhood Hits	339	Shared Neighborhood Hits	270
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

GRN_HUMAN
NC score	0.543667 (rank : 81)	θ value	4.76016e-09 (rank : 78)
Query Neighborhood Hits	808	Target Neighborhood Hits	268	Shared Neighborhood Hits	226
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

TRBM_MOUSE
NC score	0.542956 (rank : 82)	θ value	2.88788e-06 (rank : 133)
Query Neighborhood Hits	808	Target Neighborhood Hits	361	Shared Neighborhood Hits	279
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

CREL1_HUMAN
NC score	0.541676 (rank : 83)	θ value	4.1701e-05 (rank : 161)
Query Neighborhood Hits	808	Target Neighborhood Hits	441	Shared Neighborhood Hits	272
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

AGRIN_HUMAN
NC score	0.540253 (rank : 84)	θ value	3.64472e-09 (rank : 76)
Query Neighborhood Hits	808	Target Neighborhood Hits	582	Shared Neighborhood Hits	384
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

KR102_HUMAN
NC score	0.536563 (rank : 85)	θ value	8.40245e-06 (rank : 144)
Query Neighborhood Hits	808	Target Neighborhood Hits	264	Shared Neighborhood Hits	224
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR105_HUMAN
NC score	0.536182 (rank : 86)	θ value	5.81887e-07 (rank : 115)
Query Neighborhood Hits	808	Target Neighborhood Hits	271	Shared Neighborhood Hits	230
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

LRP1_HUMAN
NC score	0.536179 (rank : 87)	θ value	1.86753e-13 (rank : 48)
Query Neighborhood Hits	808	Target Neighborhood Hits	617	Shared Neighborhood Hits	400
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

FRAS1_HUMAN
NC score	0.536119 (rank : 88)	θ value	1.37539e-32 (rank : 18)
Query Neighborhood Hits	808	Target Neighborhood Hits	759	Shared Neighborhood Hits	387
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GRN_MOUSE
NC score	0.535951 (rank : 89)	θ value	2.13673e-09 (rank : 74)
Query Neighborhood Hits	808	Target Neighborhood Hits	248	Shared Neighborhood Hits	221
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KRA59_HUMAN
NC score	0.534675 (rank : 90)	θ value	0.000270298 (rank : 197)
Query Neighborhood Hits	808	Target Neighborhood Hits	310	Shared Neighborhood Hits	239
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

CREL1_MOUSE
NC score	0.533377 (rank : 91)	θ value	0.000786445 (rank : 224)
Query Neighborhood Hits	808	Target Neighborhood Hits	524	Shared Neighborhood Hits	289
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LRP1B_HUMAN
NC score	0.533069 (rank : 92)	θ value	1.09485e-13 (rank : 46)
Query Neighborhood Hits	808	Target Neighborhood Hits	602	Shared Neighborhood Hits	396
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

C1QR1_HUMAN
NC score	0.532762 (rank : 93)	θ value	6.43352e-06 (rank : 138)
Query Neighborhood Hits	808	Target Neighborhood Hits	493	Shared Neighborhood Hits	293
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
NC score	0.531962 (rank : 94)	θ value	5.81887e-07 (rank : 114)
Query Neighborhood Hits	808	Target Neighborhood Hits	342	Shared Neighborhood Hits	265
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

LRP1B_MOUSE
NC score	0.529456 (rank : 95)	θ value	4.16044e-13 (rank : 49)
Query Neighborhood Hits	808	Target Neighborhood Hits	606	Shared Neighborhood Hits	397
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FRAS1_MOUSE
NC score	0.526664 (rank : 96)	θ value	3.3877e-31 (rank : 21)
Query Neighborhood Hits	808	Target Neighborhood Hits	747	Shared Neighborhood Hits	383
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KR109_HUMAN
NC score	0.523210 (rank : 97)	θ value	6.21693e-09 (rank : 79)
Query Neighborhood Hits	808	Target Neighborhood Hits	226	Shared Neighborhood Hits	200
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

TENA_HUMAN
NC score	0.521666 (rank : 98)	θ value	7.09661e-13 (rank : 52)
Query Neighborhood Hits	808	Target Neighborhood Hits	631	Shared Neighborhood Hits	384
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

UROM_HUMAN
NC score	0.521574 (rank : 99)	θ value	0.00665767 (rank : 289)
Query Neighborhood Hits	808	Target Neighborhood Hits	284	Shared Neighborhood Hits	237
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
NC score	0.519795 (rank : 100)	θ value	0.00665767 (rank : 290)
Query Neighborhood Hits	808	Target Neighborhood Hits	276	Shared Neighborhood Hits	233
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

KRA57_HUMAN
NC score	0.519766 (rank : 101)	θ value	0.00175202 (rank : 244)
Query Neighborhood Hits	808	Target Neighborhood Hits	269	Shared Neighborhood Hits	224
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

FBLN5_HUMAN
NC score	0.519361 (rank : 102)	θ value	0.00509761 (rank : 270)
Query Neighborhood Hits	808	Target Neighborhood Hits	329	Shared Neighborhood Hits	267
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

KR10B_HUMAN
NC score	0.519144 (rank : 103)	θ value	6.21693e-09 (rank : 80)
Query Neighborhood Hits	808	Target Neighborhood Hits	269	Shared Neighborhood Hits	224
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

FBLN5_MOUSE
NC score	0.516377 (rank : 104)	θ value	0.00134147 (rank : 237)
Query Neighborhood Hits	808	Target Neighborhood Hits	317	Shared Neighborhood Hits	253
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBLN4_HUMAN
NC score	0.514064 (rank : 105)	θ value	0.0113563 (rank : 301)
Query Neighborhood Hits	808	Target Neighborhood Hits	278	Shared Neighborhood Hits	228
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

NID2_HUMAN
NC score	0.512505 (rank : 106)	θ value	0.000270298 (rank : 198)
Query Neighborhood Hits	808	Target Neighborhood Hits	456	Shared Neighborhood Hits	275
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

CUBN_MOUSE
NC score	0.510627 (rank : 107)	θ value	8.40245e-06 (rank : 142)
Query Neighborhood Hits	808	Target Neighborhood Hits	477	Shared Neighborhood Hits	332
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

TENX_HUMAN
NC score	0.509747 (rank : 108)	θ value	1.09485e-13 (rank : 47)
Query Neighborhood Hits	808	Target Neighborhood Hits	789	Shared Neighborhood Hits	408
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

MATN2_HUMAN
NC score	0.508411 (rank : 109)	θ value	7.59969e-07 (rank : 118)
Query Neighborhood Hits	808	Target Neighborhood Hits	365	Shared Neighborhood Hits	251
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

CUBN_HUMAN
NC score	0.508316 (rank : 110)	θ value	5.26297e-08 (rank : 94)
Query Neighborhood Hits	808	Target Neighborhood Hits	482	Shared Neighborhood Hits	332
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

FBLN3_HUMAN
NC score	0.508105 (rank : 111)	θ value	0.00020696 (rank : 191)
Query Neighborhood Hits	808	Target Neighborhood Hits	293	Shared Neighborhood Hits	241
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN4_MOUSE
NC score	0.507768 (rank : 112)	θ value	0.00509761 (rank : 269)
Query Neighborhood Hits	808	Target Neighborhood Hits	270	Shared Neighborhood Hits	220
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

MEGF8_HUMAN
NC score	0.507246 (rank : 113)	θ value	7.1131e-05 (rank : 173)
Query Neighborhood Hits	808	Target Neighborhood Hits	528	Shared Neighborhood Hits	339
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MATN2_MOUSE
NC score	0.507237 (rank : 114)	θ value	8.11959e-09 (rank : 83)
Query Neighborhood Hits	808	Target Neighborhood Hits	356	Shared Neighborhood Hits	251
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

TENA_MOUSE
NC score	0.506495 (rank : 115)	θ value	4.30538e-10 (rank : 70)
Query Neighborhood Hits	808	Target Neighborhood Hits	596	Shared Neighborhood Hits	368
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

NID2_MOUSE
NC score	0.506203 (rank : 116)	θ value	0.000786445 (rank : 228)
Query Neighborhood Hits	808	Target Neighborhood Hits	338	Shared Neighborhood Hits	257
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

LRP2_HUMAN
NC score	0.504359 (rank : 117)	θ value	8.95645e-16 (rank : 39)
Query Neighborhood Hits	808	Target Neighborhood Hits	573	Shared Neighborhood Hits	383
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

MEGF8_MOUSE
NC score	0.502181 (rank : 118)	θ value	1.43324e-05 (rank : 151)
Query Neighborhood Hits	808	Target Neighborhood Hits	520	Shared Neighborhood Hits	335
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NID1_MOUSE
NC score	0.501011 (rank : 119)	θ value	0.163984 (rank : 420)
Query Neighborhood Hits	808	Target Neighborhood Hits	335	Shared Neighborhood Hits	252
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

KRA54_HUMAN
NC score	0.500934 (rank : 120)	θ value	7.1131e-05 (rank : 172)
Query Neighborhood Hits	808	Target Neighborhood Hits	270	Shared Neighborhood Hits	213
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

NID1_HUMAN
NC score	0.499354 (rank : 121)	θ value	0.00509761 (rank : 278)
Query Neighborhood Hits	808	Target Neighborhood Hits	329	Shared Neighborhood Hits	259
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

PROS_HUMAN
NC score	0.498021 (rank : 122)	θ value	0.00175202 (rank : 248)
Query Neighborhood Hits	808	Target Neighborhood Hits	340	Shared Neighborhood Hits	276
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

GAS6_MOUSE
NC score	0.497981 (rank : 123)	θ value	0.0252991 (rank : 330)
Query Neighborhood Hits	808	Target Neighborhood Hits	343	Shared Neighborhood Hits	279
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBLN3_MOUSE
NC score	0.497743 (rank : 124)	θ value	0.00665767 (rank : 282)
Query Neighborhood Hits	808	Target Neighborhood Hits	279	Shared Neighborhood Hits	228
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

GAS6_HUMAN
NC score	0.496753 (rank : 125)	θ value	0.125558 (rank : 403)
Query Neighborhood Hits	808	Target Neighborhood Hits	348	Shared Neighborhood Hits	277
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

EGF_MOUSE
NC score	0.496747 (rank : 126)	θ value	0.00869519 (rank : 292)
Query Neighborhood Hits	808	Target Neighborhood Hits	358	Shared Neighborhood Hits	284
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

KR108_HUMAN
NC score	0.494991 (rank : 127)	θ value	5.26297e-08 (rank : 95)
Query Neighborhood Hits	808	Target Neighborhood Hits	226	Shared Neighborhood Hits	191
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

PROS_MOUSE
NC score	0.494334 (rank : 128)	θ value	0.00102713 (rank : 233)
Query Neighborhood Hits	808	Target Neighborhood Hits	330	Shared Neighborhood Hits	278
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

KRA55_HUMAN
NC score	0.493195 (rank : 129)	θ value	0.00020696 (rank : 192)
Query Neighborhood Hits	808	Target Neighborhood Hits	257	Shared Neighborhood Hits	207
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

PCSK5_MOUSE
NC score	0.491622 (rank : 130)	θ value	4.28545e-26 (rank : 26)
Query Neighborhood Hits	808	Target Neighborhood Hits	613	Shared Neighborhood Hits	388
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

LDLR_HUMAN
NC score	0.485515 (rank : 131)	θ value	2.79066e-09 (rank : 75)
Query Neighborhood Hits	808	Target Neighborhood Hits	375	Shared Neighborhood Hits	285
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

KR10C_HUMAN
NC score	0.484235 (rank : 132)	θ value	2.21117e-06 (rank : 128)
Query Neighborhood Hits	808	Target Neighborhood Hits	219	Shared Neighborhood Hits	186
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

EGF_HUMAN
NC score	0.483094 (rank : 133)	θ value	0.00869519 (rank : 291)
Query Neighborhood Hits	808	Target Neighborhood Hits	343	Shared Neighborhood Hits	265
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

KR511_HUMAN
NC score	0.480275 (rank : 134)	θ value	1.09739e-05 (rank : 147)
Query Neighborhood Hits	808	Target Neighborhood Hits	231	Shared Neighborhood Hits	187
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

VLDLR_HUMAN
NC score	0.475937 (rank : 135)	θ value	3.41135e-07 (rank : 113)
Query Neighborhood Hits	808	Target Neighborhood Hits	383	Shared Neighborhood Hits	281
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

MEGF9_HUMAN
NC score	0.472080 (rank : 136)	θ value	0.0193708 (rank : 316)
Query Neighborhood Hits	808	Target Neighborhood Hits	557	Shared Neighborhood Hits	342
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

VLDLR_MOUSE
NC score	0.470922 (rank : 137)	θ value	1.53129e-07 (rank : 106)
Query Neighborhood Hits	808	Target Neighborhood Hits	360	Shared Neighborhood Hits	268
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LAMA5_MOUSE
NC score	0.470285 (rank : 138)	θ value	4.0297e-08 (rank : 90)
Query Neighborhood Hits	808	Target Neighborhood Hits	828	Shared Neighborhood Hits	402
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LDLR_MOUSE
NC score	0.468472 (rank : 139)	θ value	1.17247e-07 (rank : 103)
Query Neighborhood Hits	808	Target Neighborhood Hits	382	Shared Neighborhood Hits	281
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LAMA5_HUMAN
NC score	0.466835 (rank : 140)	θ value	1.9326e-10 (rank : 68)
Query Neighborhood Hits	808	Target Neighborhood Hits	976	Shared Neighborhood Hits	400
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

EGFL7_HUMAN
NC score	0.466014 (rank : 141)	θ value	6.88961 (rank : 727)
Query Neighborhood Hits	808	Target Neighborhood Hits	325	Shared Neighborhood Hits	262
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

SUSD1_HUMAN
NC score	0.463556 (rank : 142)	θ value	3.0926 (rank : 647)
Query Neighborhood Hits	808	Target Neighborhood Hits	285	Shared Neighborhood Hits	220
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

LRP8_MOUSE
NC score	0.462278 (rank : 143)	θ value	1.29631e-06 (rank : 124)
Query Neighborhood Hits	808	Target Neighborhood Hits	385	Shared Neighborhood Hits	271
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

KRA56_HUMAN
NC score	0.461608 (rank : 144)	θ value	0.0252991 (rank : 331)
Query Neighborhood Hits	808	Target Neighborhood Hits	207	Shared Neighborhood Hits	173
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA52_HUMAN
NC score	0.458980 (rank : 145)	θ value	0.00228821 (rank : 255)
Query Neighborhood Hits	808	Target Neighborhood Hits	236	Shared Neighborhood Hits	196
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

EMR1_HUMAN
NC score	0.454912 (rank : 146)	θ value	6.43352e-06 (rank : 140)
Query Neighborhood Hits	808	Target Neighborhood Hits	382	Shared Neighborhood Hits	247
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

LAMA1_MOUSE
NC score	0.450622 (rank : 147)	θ value	3.77169e-06 (rank : 135)
Query Neighborhood Hits	808	Target Neighborhood Hits	838	Shared Neighborhood Hits	365
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NAGPA_MOUSE
NC score	0.447836 (rank : 148)	θ value	0.0113563 (rank : 302)
Query Neighborhood Hits	808	Target Neighborhood Hits	308	Shared Neighborhood Hits	276
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_HUMAN
NC score	0.447035 (rank : 149)	θ value	0.0252991 (rank : 334)
Query Neighborhood Hits	808	Target Neighborhood Hits	282	Shared Neighborhood Hits	249
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

MEGF9_MOUSE
NC score	0.446799 (rank : 150)	θ value	0.000602161 (rank : 214)
Query Neighborhood Hits	808	Target Neighborhood Hits	896	Shared Neighborhood Hits	321
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

EGFL7_MOUSE
NC score	0.446259 (rank : 151)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	808	Target Neighborhood Hits	287	Shared Neighborhood Hits	245
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

LRP8_HUMAN
NC score	0.442003 (rank : 152)	θ value	2.88788e-06 (rank : 131)
Query Neighborhood Hits	808	Target Neighborhood Hits	346	Shared Neighborhood Hits	246
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

KR10A_HUMAN
NC score	0.438564 (rank : 153)	θ value	2.44474e-05 (rank : 156)
Query Neighborhood Hits	808	Target Neighborhood Hits	232	Shared Neighborhood Hits	196
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KRA47_HUMAN
NC score	0.436953 (rank : 154)	θ value	0.00665767 (rank : 285)
Query Neighborhood Hits	808	Target Neighborhood Hits	204	Shared Neighborhood Hits	172
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA94_HUMAN
NC score	0.436906 (rank : 155)	θ value	0.00102713 (rank : 231)
Query Neighborhood Hits	808	Target Neighborhood Hits	204	Shared Neighborhood Hits	183
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA45_HUMAN
NC score	0.434036 (rank : 156)	θ value	0.00175202 (rank : 243)
Query Neighborhood Hits	808	Target Neighborhood Hits	194	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KR171_HUMAN
NC score	0.432458 (rank : 157)	θ value	0.62314 (rank : 501)
Query Neighborhood Hits	808	Target Neighborhood Hits	144	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KRA13_HUMAN
NC score	0.432376 (rank : 158)	θ value	0.00102713 (rank : 230)
Query Neighborhood Hits	808	Target Neighborhood Hits	144	Shared Neighborhood Hits	125
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

LAMA1_HUMAN
NC score	0.430933 (rank : 159)	θ value	3.19293e-05 (rank : 159)
Query Neighborhood Hits	808	Target Neighborhood Hits	804	Shared Neighborhood Hits	356
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

EDIL3_MOUSE
NC score	0.430000 (rank : 160)	θ value	0.00134147 (rank : 236)
Query Neighborhood Hits	808	Target Neighborhood Hits	317	Shared Neighborhood Hits	260
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EMR1_MOUSE
NC score	0.428392 (rank : 161)	θ value	6.87365e-08 (rank : 98)
Query Neighborhood Hits	808	Target Neighborhood Hits	349	Shared Neighborhood Hits	227
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EGFL8_HUMAN
NC score	0.426501 (rank : 162)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	808	Target Neighborhood Hits	270	Shared Neighborhood Hits	219
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EMR2_HUMAN
NC score	0.426424 (rank : 163)	θ value	0.00175202 (rank : 241)
Query Neighborhood Hits	808	Target Neighborhood Hits	345	Shared Neighborhood Hits	233
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

LAMB2_HUMAN
NC score	0.426115 (rank : 164)	θ value	0.00035302 (rank : 201)
Query Neighborhood Hits	808	Target Neighborhood Hits	692	Shared Neighborhood Hits	319
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LRP4_MOUSE
NC score	0.425599 (rank : 165)	θ value	4.0297e-08 (rank : 91)
Query Neighborhood Hits	808	Target Neighborhood Hits	351	Shared Neighborhood Hits	247
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

COMP_MOUSE
NC score	0.424847 (rank : 166)	θ value	0.000786445 (rank : 223)
Query Neighborhood Hits	808	Target Neighborhood Hits	290	Shared Neighborhood Hits	247
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

LRP4_HUMAN
NC score	0.424834 (rank : 167)	θ value	8.97725e-08 (rank : 101)
Query Neighborhood Hits	808	Target Neighborhood Hits	355	Shared Neighborhood Hits	252
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

CD97_HUMAN
NC score	0.421978 (rank : 168)	θ value	0.000786445 (rank : 221)
Query Neighborhood Hits	808	Target Neighborhood Hits	353	Shared Neighborhood Hits	237
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

LAMB2_MOUSE
NC score	0.421623 (rank : 169)	θ value	0.0252991 (rank : 332)
Query Neighborhood Hits	808	Target Neighborhood Hits	722	Shared Neighborhood Hits	316
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

EGFL8_MOUSE
NC score	0.421338 (rank : 170)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	808	Target Neighborhood Hits	266	Shared Neighborhood Hits	224
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EDIL3_HUMAN
NC score	0.420991 (rank : 171)	θ value	0.0113563 (rank : 300)
Query Neighborhood Hits	808	Target Neighborhood Hits	292	Shared Neighborhood Hits	242
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

CD248_HUMAN
NC score	0.420359 (rank : 172)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	808	Target Neighborhood Hits	679	Shared Neighborhood Hits	265
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

KR103_HUMAN
NC score	0.419782 (rank : 173)	θ value	0.000786445 (rank : 225)
Query Neighborhood Hits	808	Target Neighborhood Hits	212	Shared Neighborhood Hits	187
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

TSP4_MOUSE
NC score	0.419650 (rank : 174)	θ value	8.99809 (rank : 806)
Query Neighborhood Hits	808	Target Neighborhood Hits	276	Shared Neighborhood Hits	244
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

KR412_HUMAN
NC score	0.419301 (rank : 175)	θ value	0.000270298 (rank : 196)
Query Neighborhood Hits	808	Target Neighborhood Hits	178	Shared Neighborhood Hits	154
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR510_HUMAN
NC score	0.418658 (rank : 176)	θ value	0.00509761 (rank : 274)
Query Neighborhood Hits	808	Target Neighborhood Hits	217	Shared Neighborhood Hits	172
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA98_HUMAN
NC score	0.417700 (rank : 177)	θ value	0.000786445 (rank : 226)
Query Neighborhood Hits	808	Target Neighborhood Hits	185	Shared Neighborhood Hits	155
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KR414_HUMAN
NC score	0.417500 (rank : 178)	θ value	0.00298849 (rank : 260)
Query Neighborhood Hits	808	Target Neighborhood Hits	199	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

LAMC3_MOUSE
NC score	0.417070 (rank : 179)	θ value	6.43352e-06 (rank : 141)
Query Neighborhood Hits	808	Target Neighborhood Hits	624	Shared Neighborhood Hits	317
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_HUMAN
NC score	0.417040 (rank : 180)	θ value	0.00228821 (rank : 256)
Query Neighborhood Hits	808	Target Neighborhood Hits	588	Shared Neighborhood Hits	331
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MATN4_HUMAN
NC score	0.416496 (rank : 181)	θ value	0.163984 (rank : 418)
Query Neighborhood Hits	808	Target Neighborhood Hits	287	Shared Neighborhood Hits	211
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

SLIT1_HUMAN
NC score	0.414121 (rank : 182)	θ value	0.00175202 (rank : 249)
Query Neighborhood Hits	808	Target Neighborhood Hits	700	Shared Neighborhood Hits	350
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

KRA92_HUMAN
NC score	0.413727 (rank : 183)	θ value	0.00020696 (rank : 193)
Query Neighborhood Hits	808	Target Neighborhood Hits	198	Shared Neighborhood Hits	169
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

TSP4_HUMAN
NC score	0.413699 (rank : 184)	θ value	5.27518 (rank : 710)
Query Neighborhood Hits	808	Target Neighborhood Hits	277	Shared Neighborhood Hits	237
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

MATN3_HUMAN
NC score	0.411862 (rank : 185)	θ value	0.0736092 (rank : 380)
Query Neighborhood Hits	808	Target Neighborhood Hits	268	Shared Neighborhood Hits	190
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

KRA93_HUMAN
NC score	0.411469 (rank : 186)	θ value	0.0193708 (rank : 315)
Query Neighborhood Hits	808	Target Neighborhood Hits	203	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

CD248_MOUSE
NC score	0.410551 (rank : 187)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	808	Target Neighborhood Hits	578	Shared Neighborhood Hits	247
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MATN3_MOUSE
NC score	0.407672 (rank : 188)	θ value	0.813845 (rank : 520)
Query Neighborhood Hits	808	Target Neighborhood Hits	261	Shared Neighborhood Hits	193
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

LAMA2_HUMAN
NC score	0.407190 (rank : 189)	θ value	5.26297e-08 (rank : 96)
Query Neighborhood Hits	808	Target Neighborhood Hits	1092	Shared Neighborhood Hits	361
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

SLIT1_MOUSE
NC score	0.405381 (rank : 190)	θ value	0.00298849 (rank : 261)
Query Neighborhood Hits	808	Target Neighborhood Hits	715	Shared Neighborhood Hits	357
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

COMP_HUMAN
NC score	0.402958 (rank : 191)	θ value	0.0252991 (rank : 327)
Query Neighborhood Hits	808	Target Neighborhood Hits	258	Shared Neighborhood Hits	221
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

USH2A_MOUSE
NC score	0.402720 (rank : 192)	θ value	9.29e-05 (rank : 177)
Query Neighborhood Hits	808	Target Neighborhood Hits	626	Shared Neighborhood Hits	339
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

SLIT2_HUMAN
NC score	0.402331 (rank : 193)	θ value	0.000602161 (rank : 217)
Query Neighborhood Hits	808	Target Neighborhood Hits	708	Shared Neighborhood Hits	359
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

KRA44_HUMAN
NC score	0.398909 (rank : 194)	θ value	0.00869519 (rank : 296)
Query Neighborhood Hits	808	Target Neighborhood Hits	162	Shared Neighborhood Hits	143
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

SLIT3_MOUSE
NC score	0.397360 (rank : 195)	θ value	0.0148317 (rank : 310)
Query Neighborhood Hits	808	Target Neighborhood Hits	700	Shared Neighborhood Hits	344
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

LAMB1_MOUSE
NC score	0.395667 (rank : 196)	θ value	2.88788e-06 (rank : 130)
Query Neighborhood Hits	808	Target Neighborhood Hits	919	Shared Neighborhood Hits	305
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SLIT2_MOUSE
NC score	0.395122 (rank : 197)	θ value	0.000602161 (rank : 218)
Query Neighborhood Hits	808	Target Neighborhood Hits	684	Shared Neighborhood Hits	338
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

MATN4_MOUSE
NC score	0.392760 (rank : 198)	θ value	1.38821 (rank : 571)
Query Neighborhood Hits	808	Target Neighborhood Hits	277	Shared Neighborhood Hits	202
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

LAMA2_MOUSE
NC score	0.386915 (rank : 199)	θ value	1.69304e-06 (rank : 127)
Query Neighborhood Hits	808	Target Neighborhood Hits	1198	Shared Neighborhood Hits	365
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB3_MOUSE
NC score	0.386234 (rank : 200)	θ value	3.41135e-07 (rank : 110)
Query Neighborhood Hits	808	Target Neighborhood Hits	444	Shared Neighborhood Hits	243
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC2_MOUSE
NC score	0.385191 (rank : 201)	θ value	0.0148317 (rank : 309)
Query Neighborhood Hits	808	Target Neighborhood Hits	614	Shared Neighborhood Hits	306
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC1_MOUSE
NC score	0.384965 (rank : 202)	θ value	2.44474e-05 (rank : 157)
Query Neighborhood Hits	808	Target Neighborhood Hits	856	Shared Neighborhood Hits	315
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

TSP1_HUMAN
NC score	0.384776 (rank : 203)	θ value	0.00509761 (rank : 281)
Query Neighborhood Hits	808	Target Neighborhood Hits	389	Shared Neighborhood Hits	281
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP3_MOUSE
NC score	0.383622 (rank : 204)	θ value	6.88961 (rank : 758)
Query Neighborhood Hits	808	Target Neighborhood Hits	247	Shared Neighborhood Hits	214
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

KRA11_HUMAN
NC score	0.383619 (rank : 205)	θ value	0.00175202 (rank : 242)
Query Neighborhood Hits	808	Target Neighborhood Hits	155	Shared Neighborhood Hits	129
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

TSP1_MOUSE
NC score	0.383538 (rank : 206)	θ value	0.00665767 (rank : 288)
Query Neighborhood Hits	808	Target Neighborhood Hits	396	Shared Neighborhood Hits	285
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

SLIT3_HUMAN
NC score	0.382840 (rank : 207)	θ value	0.00035302 (rank : 204)
Query Neighborhood Hits	808	Target Neighborhood Hits	682	Shared Neighborhood Hits	328
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

LAMB1_HUMAN
NC score	0.382560 (rank : 208)	θ value	1.29631e-06 (rank : 123)
Query Neighborhood Hits	808	Target Neighborhood Hits	1018	Shared Neighborhood Hits	323
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

KRA15_HUMAN
NC score	0.381739 (rank : 209)	θ value	0.000158464 (rank : 185)
Query Neighborhood Hits	808	Target Neighborhood Hits	126	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

CSPG2_MOUSE
NC score	0.381045 (rank : 210)	θ value	7.84624e-12 (rank : 55)
Query Neighborhood Hits	808	Target Neighborhood Hits	711	Shared Neighborhood Hits	299
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

HHIP_HUMAN
NC score	0.380992 (rank : 211)	θ value	8.99809 (rank : 780)
Query Neighborhood Hits	808	Target Neighborhood Hits	249	Shared Neighborhood Hits	223
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

SORL_MOUSE
NC score	0.380435 (rank : 212)	θ value	1.47974e-10 (rank : 66)
Query Neighborhood Hits	808	Target Neighborhood Hits	439	Shared Neighborhood Hits	252
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TSP3_HUMAN
NC score	0.379295 (rank : 213)	θ value	θ > 10 (rank : 1126)
Query Neighborhood Hits	808	Target Neighborhood Hits	250	Shared Neighborhood Hits	210
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

KRA99_HUMAN
NC score	0.377058 (rank : 214)	θ value	0.00509761 (rank : 276)
Query Neighborhood Hits	808	Target Neighborhood Hits	173	Shared Neighborhood Hits	149
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMC1_HUMAN
NC score	0.376035 (rank : 215)	θ value	0.000158464 (rank : 186)
Query Neighborhood Hits	808	Target Neighborhood Hits	922	Shared Neighborhood Hits	320
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMA3_MOUSE
NC score	0.375170 (rank : 216)	θ value	9.29e-05 (rank : 176)
Query Neighborhood Hits	808	Target Neighborhood Hits	859	Shared Neighborhood Hits	348
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMC2_HUMAN
NC score	0.373237 (rank : 217)	θ value	0.00134147 (rank : 238)
Query Neighborhood Hits	808	Target Neighborhood Hits	715	Shared Neighborhood Hits	295
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

CSPG2_HUMAN
NC score	0.371489 (rank : 218)	θ value	1.06045e-08 (rank : 84)
Query Neighborhood Hits	808	Target Neighborhood Hits	681	Shared Neighborhood Hits	291
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

USH2A_HUMAN
NC score	0.369428 (rank : 219)	θ value	0.000602161 (rank : 219)
Query Neighborhood Hits	808	Target Neighborhood Hits	600	Shared Neighborhood Hits	311
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

SORL_HUMAN
NC score	0.368834 (rank : 220)	θ value	1.25267e-09 (rank : 72)
Query Neighborhood Hits	808	Target Neighborhood Hits	440	Shared Neighborhood Hits	250
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

NFX1_HUMAN
NC score	0.368433 (rank : 221)	θ value	2.36792 (rank : 619)
Query Neighborhood Hits	808	Target Neighborhood Hits	405	Shared Neighborhood Hits	208
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

CD97_MOUSE
NC score	0.366074 (rank : 222)	θ value	0.0431538 (rank : 351)
Query Neighborhood Hits	808	Target Neighborhood Hits	295	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

ITB6_MOUSE
NC score	0.362770 (rank : 223)	θ value	0.0193708 (rank : 314)
Query Neighborhood Hits	808	Target Neighborhood Hits	341	Shared Neighborhood Hits	278
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB5_MOUSE
NC score	0.360264 (rank : 224)	θ value	0.00509761 (rank : 273)
Query Neighborhood Hits	808	Target Neighborhood Hits	329	Shared Neighborhood Hits	287
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

PROZ_MOUSE
NC score	0.359599 (rank : 225)	θ value	0.00228821 (rank : 257)
Query Neighborhood Hits	808	Target Neighborhood Hits	410	Shared Neighborhood Hits	237
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_HUMAN
NC score	0.359542 (rank : 226)	θ value	0.0736092 (rank : 383)
Query Neighborhood Hits	808	Target Neighborhood Hits	422	Shared Neighborhood Hits	248
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

LCE1F_HUMAN
NC score	0.359334 (rank : 227)	θ value	0.0961366 (rank : 390)
Query Neighborhood Hits	808	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

HMCN1_HUMAN
NC score	0.357843 (rank : 228)	θ value	7.84624e-12 (rank : 56)
Query Neighborhood Hits	808	Target Neighborhood Hits	983	Shared Neighborhood Hits	334
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KR410_HUMAN
NC score	0.357476 (rank : 229)	θ value	0.21417 (rank : 433)
Query Neighborhood Hits	808	Target Neighborhood Hits	156	Shared Neighborhood Hits	140
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

LCE1E_HUMAN
NC score	0.356519 (rank : 230)	θ value	0.0961366 (rank : 389)
Query Neighborhood Hits	808	Target Neighborhood Hits	53	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

ITB2_MOUSE
NC score	0.354942 (rank : 231)	θ value	5.44631e-05 (rank : 168)
Query Neighborhood Hits	808	Target Neighborhood Hits	326	Shared Neighborhood Hits	281
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

NTNG2_MOUSE
NC score	0.353786 (rank : 232)	θ value	θ > 10 (rank : 1030)
Query Neighborhood Hits	808	Target Neighborhood Hits	276	Shared Neighborhood Hits	232
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ELTD1_MOUSE
NC score	0.353321 (rank : 233)	θ value	0.125558 (rank : 401)
Query Neighborhood Hits	808	Target Neighborhood Hits	288	Shared Neighborhood Hits	191
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

PGBM_MOUSE
NC score	0.353180 (rank : 234)	θ value	0.00390308 (rank : 265)
Query Neighborhood Hits	808	Target Neighborhood Hits	1073	Shared Neighborhood Hits	385
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ITB3_HUMAN
NC score	0.352321 (rank : 235)	θ value	0.00665767 (rank : 284)
Query Neighborhood Hits	808	Target Neighborhood Hits	325	Shared Neighborhood Hits	284
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

HHIP_MOUSE
NC score	0.351943 (rank : 236)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	808	Target Neighborhood Hits	219	Shared Neighborhood Hits	192
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

LCE1A_HUMAN
NC score	0.351830 (rank : 237)	θ value	1.38821 (rank : 568)
Query Neighborhood Hits	808	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LAMB3_HUMAN
NC score	0.351817 (rank : 238)	θ value	0.0148317 (rank : 308)
Query Neighborhood Hits	808	Target Neighborhood Hits	461	Shared Neighborhood Hits	212
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

NTNG2_HUMAN
NC score	0.348616 (rank : 239)	θ value	6.88961 (rank : 750)
Query Neighborhood Hits	808	Target Neighborhood Hits	276	Shared Neighborhood Hits	224
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ITB6_HUMAN
NC score	0.348335 (rank : 240)	θ value	0.0431538 (rank : 355)
Query Neighborhood Hits	808	Target Neighborhood Hits	318	Shared Neighborhood Hits	271
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

CSPG3_MOUSE
NC score	0.347668 (rank : 241)	θ value	0.00020696 (rank : 190)
Query Neighborhood Hits	808	Target Neighborhood Hits	657	Shared Neighborhood Hits	285
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TSP2_HUMAN
NC score	0.347223 (rank : 242)	θ value	7.1131e-05 (rank : 174)
Query Neighborhood Hits	808	Target Neighborhood Hits	359	Shared Neighborhood Hits	270
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

CSPG3_HUMAN
NC score	0.345841 (rank : 243)	θ value	1.43324e-05 (rank : 149)
Query Neighborhood Hits	808	Target Neighborhood Hits	676	Shared Neighborhood Hits	274
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LCE1C_HUMAN
NC score	0.345545 (rank : 244)	θ value	1.06291 (rank : 543)
Query Neighborhood Hits	808	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

TSP2_MOUSE
NC score	0.344572 (rank : 245)	θ value	0.000158464 (rank : 188)
Query Neighborhood Hits	808	Target Neighborhood Hits	352	Shared Neighborhood Hits	263
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ITB5_HUMAN
NC score	0.343613 (rank : 246)	θ value	0.00869519 (rank : 295)
Query Neighborhood Hits	808	Target Neighborhood Hits	310	Shared Neighborhood Hits	269
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB7_HUMAN
NC score	0.341617 (rank : 247)	θ value	0.000461057 (rank : 210)
Query Neighborhood Hits	808	Target Neighborhood Hits	290	Shared Neighborhood Hits	250
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

LCE1B_HUMAN
NC score	0.341151 (rank : 248)	θ value	1.38821 (rank : 569)
Query Neighborhood Hits	808	Target Neighborhood Hits	58	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

PGBM_HUMAN
NC score	0.339966 (rank : 249)	θ value	0.0193708 (rank : 323)
Query Neighborhood Hits	808	Target Neighborhood Hits	1113	Shared Neighborhood Hits	386
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TENR_MOUSE
NC score	0.339438 (rank : 250)	θ value	0.21417 (rank : 440)
Query Neighborhood Hits	808	Target Neighborhood Hits	531	Shared Neighborhood Hits	318
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

KRA42_HUMAN
NC score	0.335278 (rank : 251)	θ value	0.00509761 (rank : 275)
Query Neighborhood Hits	808	Target Neighborhood Hits	149	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

TENR_HUMAN
NC score	0.334376 (rank : 252)	θ value	0.0431538 (rank : 362)
Query Neighborhood Hits	808	Target Neighborhood Hits	526	Shared Neighborhood Hits	311
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ITB3_MOUSE
NC score	0.333110 (rank : 253)	θ value	1.06291 (rank : 542)
Query Neighborhood Hits	808	Target Neighborhood Hits	319	Shared Neighborhood Hits	266
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB1_HUMAN
NC score	0.331643 (rank : 254)	θ value	0.163984 (rank : 416)
Query Neighborhood Hits	808	Target Neighborhood Hits	298	Shared Neighborhood Hits	253
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

RECK_HUMAN
NC score	0.331227 (rank : 255)	θ value	4.92598e-06 (rank : 137)
Query Neighborhood Hits	808	Target Neighborhood Hits	189	Shared Neighborhood Hits	139
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

LCE3A_HUMAN
NC score	0.330042 (rank : 256)	θ value	0.0563607 (rank : 366)
Query Neighborhood Hits	808	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

ITB7_MOUSE
NC score	0.326912 (rank : 257)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	808	Target Neighborhood Hits	277	Shared Neighborhood Hits	240
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

LYAM3_MOUSE
NC score	0.326067 (rank : 258)	θ value	4.0297e-08 (rank : 92)
Query Neighborhood Hits	808	Target Neighborhood Hits	390	Shared Neighborhood Hits	245
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MFGM_MOUSE
NC score	0.325364 (rank : 259)	θ value	0.00175202 (rank : 246)
Query Neighborhood Hits	808	Target Neighborhood Hits	233	Shared Neighborhood Hits	188
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

ATRN_MOUSE
NC score	0.324313 (rank : 260)	θ value	6.88961 (rank : 719)
Query Neighborhood Hits	808	Target Neighborhood Hits	519	Shared Neighborhood Hits	296
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ITB2_HUMAN
NC score	0.323205 (rank : 261)	θ value	0.00390308 (rank : 264)
Query Neighborhood Hits	808	Target Neighborhood Hits	282	Shared Neighborhood Hits	241
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB1_MOUSE
NC score	0.323033 (rank : 262)	θ value	1.38821 (rank : 565)
Query Neighborhood Hits	808	Target Neighborhood Hits	283	Shared Neighborhood Hits	242
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ATRN_HUMAN
NC score	0.322718 (rank : 263)	θ value	4.03905 (rank : 656)
Query Neighborhood Hits	808	Target Neighborhood Hits	525	Shared Neighborhood Hits	298
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

NTNG1_HUMAN
NC score	0.320485 (rank : 264)	θ value	θ > 10 (rank : 1028)
Query Neighborhood Hits	808	Target Neighborhood Hits	247	Shared Neighborhood Hits	203
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LAMA4_MOUSE
NC score	0.319403 (rank : 265)	θ value	0.0431538 (rank : 356)
Query Neighborhood Hits	808	Target Neighborhood Hits	584	Shared Neighborhood Hits	227
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

ITB4_HUMAN
NC score	0.318293 (rank : 266)	θ value	0.0961366 (rank : 388)
Query Neighborhood Hits	808	Target Neighborhood Hits	458	Shared Neighborhood Hits	269
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

NTNG1_MOUSE
NC score	0.317269 (rank : 267)	θ value	θ > 10 (rank : 1029)
Query Neighborhood Hits	808	Target Neighborhood Hits	246	Shared Neighborhood Hits	199
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LAMA3_HUMAN
NC score	0.310248 (rank : 268)	θ value	0.00869519 (rank : 297)
Query Neighborhood Hits	808	Target Neighborhood Hits	760	Shared Neighborhood Hits	264
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

RECK_MOUSE
NC score	0.302588 (rank : 269)	θ value	1.43324e-05 (rank : 153)
Query Neighborhood Hits	808	Target Neighborhood Hits	158	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

LAMA4_HUMAN
NC score	0.294222 (rank : 270)	θ value	θ > 10 (rank : 978)
Query Neighborhood Hits	808	Target Neighborhood Hits	708	Shared Neighborhood Hits	224
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LYAM3_HUMAN
NC score	0.291407 (rank : 271)	θ value	0.000158464 (rank : 187)
Query Neighborhood Hits	808	Target Neighborhood Hits	378	Shared Neighborhood Hits	234
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

TENN_MOUSE
NC score	0.290213 (rank : 272)	θ value	0.00509761 (rank : 279)
Query Neighborhood Hits	808	Target Neighborhood Hits	484	Shared Neighborhood Hits	287
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CFC1_HUMAN
NC score	0.289206 (rank : 273)	θ value	0.21417 (rank : 428)
Query Neighborhood Hits	808	Target Neighborhood Hits	148	Shared Neighborhood Hits	127
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

LYAM2_HUMAN
NC score	0.289188 (rank : 274)	θ value	0.00035302 (rank : 202)
Query Neighborhood Hits	808	Target Neighborhood Hits	394	Shared Neighborhood Hits	248
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

ITB8_HUMAN
NC score	0.286097 (rank : 275)	θ value	0.365318 (rank : 469)
Query Neighborhood Hits	808	Target Neighborhood Hits	280	Shared Neighborhood Hits	230
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

LYAM2_MOUSE
NC score	0.284196 (rank : 276)	θ value	0.0563607 (rank : 367)
Query Neighborhood Hits	808	Target Neighborhood Hits	420	Shared Neighborhood Hits	273
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

FATH_HUMAN
NC score	0.280595 (rank : 277)	θ value	4.1701e-05 (rank : 164)
Query Neighborhood Hits	808	Target Neighborhood Hits	570	Shared Neighborhood Hits	301
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

KRA24_HUMAN
NC score	0.276966 (rank : 278)	θ value	2.36792 (rank : 613)
Query Neighborhood Hits	808	Target Neighborhood Hits	192	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

PCSK5_HUMAN
NC score	0.275301 (rank : 279)	θ value	0.00035302 (rank : 203)
Query Neighborhood Hits	808	Target Neighborhood Hits	291	Shared Neighborhood Hits	228
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

CELR2_HUMAN
NC score	0.273217 (rank : 280)	θ value	0.00020696 (rank : 189)
Query Neighborhood Hits	808	Target Neighborhood Hits	657	Shared Neighborhood Hits	342
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

LCE1D_HUMAN
NC score	0.271040 (rank : 281)	θ value	5.27518 (rank : 697)
Query Neighborhood Hits	808	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

CELR3_HUMAN
NC score	0.268014 (rank : 282)	θ value	0.00035302 (rank : 200)
Query Neighborhood Hits	808	Target Neighborhood Hits	680	Shared Neighborhood Hits	319
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
NC score	0.266541 (rank : 283)	θ value	0.00228821 (rank : 251)
Query Neighborhood Hits	808	Target Neighborhood Hits	687	Shared Neighborhood Hits	335
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

TENN_HUMAN
NC score	0.264547 (rank : 284)	θ value	0.47712 (rank : 491)
Query Neighborhood Hits	808	Target Neighborhood Hits	453	Shared Neighborhood Hits	271
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

ELTD1_HUMAN
NC score	0.263169 (rank : 285)	θ value	1.38821 (rank : 561)
Query Neighborhood Hits	808	Target Neighborhood Hits	269	Shared Neighborhood Hits	177
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

MCSP_MOUSE
NC score	0.261502 (rank : 286)	θ value	0.000786445 (rank : 227)
Query Neighborhood Hits	808	Target Neighborhood Hits	108	Shared Neighborhood Hits	77
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

KR413_HUMAN
NC score	0.260743 (rank : 287)	θ value	1.38821 (rank : 567)
Query Neighborhood Hits	808	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

CELR1_HUMAN
NC score	0.254195 (rank : 288)	θ value	4.1701e-05 (rank : 160)
Query Neighborhood Hits	808	Target Neighborhood Hits	613	Shared Neighborhood Hits	299
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

TDGF1_MOUSE
NC score	0.253511 (rank : 289)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	808	Target Neighborhood Hits	146	Shared Neighborhood Hits	125
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

NET4_HUMAN
NC score	0.253368 (rank : 290)	θ value	0.21417 (rank : 435)
Query Neighborhood Hits	808	Target Neighborhood Hits	191	Shared Neighborhood Hits	156
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET2_MOUSE
NC score	0.252945 (rank : 291)	θ value	0.0736092 (rank : 381)
Query Neighborhood Hits	808	Target Neighborhood Hits	193	Shared Neighborhood Hits	154
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

CELR1_MOUSE
NC score	0.252200 (rank : 292)	θ value	0.0330416 (rank : 341)
Query Neighborhood Hits	808	Target Neighborhood Hits	617	Shared Neighborhood Hits	301
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

LRP6_HUMAN
NC score	0.251288 (rank : 293)	θ value	6.88961 (rank : 740)
Query Neighborhood Hits	808	Target Neighborhood Hits	235	Shared Neighborhood Hits	155
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

NET2_HUMAN
NC score	0.250958 (rank : 294)	θ value	0.21417 (rank : 434)
Query Neighborhood Hits	808	Target Neighborhood Hits	194	Shared Neighborhood Hits	149
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

CFC1_MOUSE
NC score	0.250650 (rank : 295)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	808	Target Neighborhood Hits	125	Shared Neighborhood Hits	108
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

LRP5_MOUSE
NC score	0.250402 (rank : 296)	θ value	5.27518 (rank : 698)
Query Neighborhood Hits	808	Target Neighborhood Hits	236	Shared Neighborhood Hits	152
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_MOUSE
NC score	0.249480 (rank : 297)	θ value	6.88961 (rank : 741)
Query Neighborhood Hits	808	Target Neighborhood Hits	232	Shared Neighborhood Hits	152
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

NET4_MOUSE
NC score	0.248831 (rank : 298)	θ value	0.365318 (rank : 471)
Query Neighborhood Hits	808	Target Neighborhood Hits	180	Shared Neighborhood Hits	154
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

PCSK6_HUMAN
NC score	0.246341 (rank : 299)	θ value	0.000602161 (rank : 215)
Query Neighborhood Hits	808	Target Neighborhood Hits	298	Shared Neighborhood Hits	188
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

LCE4A_HUMAN
NC score	0.244772 (rank : 300)	θ value	0.813845 (rank : 517)
Query Neighborhood Hits	808	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

CELR2_MOUSE
NC score	0.244740 (rank : 301)	θ value	0.000158464 (rank : 182)
Query Neighborhood Hits	808	Target Neighborhood Hits	584	Shared Neighborhood Hits	297
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

MUC13_MOUSE
NC score	0.244091 (rank : 302)	θ value	6.88961 (rank : 748)
Query Neighborhood Hits	808	Target Neighborhood Hits	447	Shared Neighborhood Hits	206
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MAMC2_MOUSE
NC score	0.243618 (rank : 303)	θ value	2.35696e-16 (rank : 36)
Query Neighborhood Hits	808	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

LRP5_HUMAN
NC score	0.243352 (rank : 304)	θ value	θ > 10 (rank : 989)
Query Neighborhood Hits	808	Target Neighborhood Hits	224	Shared Neighborhood Hits	144
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

MT4_MOUSE
NC score	0.243293 (rank : 305)	θ value	0.0431538 (rank : 358)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

CRDL2_MOUSE
NC score	0.242389 (rank : 306)	θ value	0.00175202 (rank : 240)
Query Neighborhood Hits	808	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

MAMC2_HUMAN
NC score	0.242016 (rank : 307)	θ value	5.8054e-15 (rank : 40)
Query Neighborhood Hits	808	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

UROL1_MOUSE
NC score	0.240449 (rank : 308)	θ value	θ > 10 (rank : 1130)
Query Neighborhood Hits	808	Target Neighborhood Hits	235	Shared Neighborhood Hits	145
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

LCE3B_HUMAN
NC score	0.240231 (rank : 309)	θ value	1.81305 (rank : 588)
Query Neighborhood Hits	808	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

CRDL2_HUMAN
NC score	0.239527 (rank : 310)	θ value	0.000270298 (rank : 195)
Query Neighborhood Hits	808	Target Neighborhood Hits	99	Shared Neighborhood Hits	73
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

LYAM1_MOUSE
NC score	0.232339 (rank : 311)	θ value	0.813845 (rank : 519)
Query Neighborhood Hits	808	Target Neighborhood Hits	332	Shared Neighborhood Hits	202
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

HABP2_HUMAN
NC score	0.231703 (rank : 312)	θ value	0.00869519 (rank : 293)
Query Neighborhood Hits	808	Target Neighborhood Hits	431	Shared Neighborhood Hits	242
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

CHRD_HUMAN
NC score	0.231518 (rank : 313)	θ value	0.000786445 (rank : 222)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

WFDC3_HUMAN
NC score	0.231388 (rank : 314)	θ value	0.279714 (rank : 458)
Query Neighborhood Hits	808	Target Neighborhood Hits	138	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

HABP2_MOUSE
NC score	0.229735 (rank : 315)	θ value	0.00509761 (rank : 271)
Query Neighborhood Hits	808	Target Neighborhood Hits	445	Shared Neighborhood Hits	248
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LYAM1_HUMAN
NC score	0.226519 (rank : 316)	θ value	8.99809 (rank : 782)
Query Neighborhood Hits	808	Target Neighborhood Hits	315	Shared Neighborhood Hits	199
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

TEFF2_MOUSE
NC score	0.224395 (rank : 317)	θ value	θ > 10 (rank : 1099)
Query Neighborhood Hits	808	Target Neighborhood Hits	214	Shared Neighborhood Hits	142
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEFF2_HUMAN
NC score	0.222337 (rank : 318)	θ value	θ > 10 (rank : 1098)
Query Neighborhood Hits	808	Target Neighborhood Hits	211	Shared Neighborhood Hits	140
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

CRDL1_MOUSE
NC score	0.221924 (rank : 319)	θ value	0.0736092 (rank : 377)
Query Neighborhood Hits	808	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

UROL1_HUMAN
NC score	0.221551 (rank : 320)	θ value	θ > 10 (rank : 1129)
Query Neighborhood Hits	808	Target Neighborhood Hits	213	Shared Neighborhood Hits	132
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

KR124_HUMAN
NC score	0.218601 (rank : 321)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	808	Target Neighborhood Hits	124	Shared Neighborhood Hits	103
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

LCE2A_HUMAN
NC score	0.217078 (rank : 322)	θ value	1.81305 (rank : 587)
Query Neighborhood Hits	808	Target Neighborhood Hits	50	Shared Neighborhood Hits	36
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

CHRD_MOUSE
NC score	0.217031 (rank : 323)	θ value	0.0431538 (rank : 352)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CRAC1_MOUSE
NC score	0.216412 (rank : 324)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	808	Target Neighborhood Hits	112	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

ZNFX1_HUMAN
NC score	0.215972 (rank : 325)	θ value	0.0252991 (rank : 338)
Query Neighborhood Hits	808	Target Neighborhood Hits	308	Shared Neighborhood Hits	160
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

LCE2C_HUMAN
NC score	0.214783 (rank : 326)	θ value	1.06291 (rank : 544)
Query Neighborhood Hits	808	Target Neighborhood Hits	53	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

CRAC1_HUMAN
NC score	0.214780 (rank : 327)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	808	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

PGCB_MOUSE
NC score	0.212990 (rank : 328)	θ value	0.00102713 (rank : 232)
Query Neighborhood Hits	808	Target Neighborhood Hits	459	Shared Neighborhood Hits	195
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

TNR25_HUMAN
NC score	0.212516 (rank : 329)	θ value	0.00665767 (rank : 286)
Query Neighborhood Hits	808	Target Neighborhood Hits	172	Shared Neighborhood Hits	103
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

BMP1_MOUSE
NC score	0.212432 (rank : 330)	θ value	0.47712 (rank : 481)
Query Neighborhood Hits	808	Target Neighborhood Hits	236	Shared Neighborhood Hits	160
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

NET1_HUMAN
NC score	0.212206 (rank : 331)	θ value	θ > 10 (rank : 1012)
Query Neighborhood Hits	808	Target Neighborhood Hits	149	Shared Neighborhood Hits	116
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

SUSD2_MOUSE
NC score	0.211204 (rank : 332)	θ value	0.00035302 (rank : 205)
Query Neighborhood Hits	808	Target Neighborhood Hits	104	Shared Neighborhood Hits	41
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

BMP1_HUMAN
NC score	0.211164 (rank : 333)	θ value	0.47712 (rank : 480)
Query Neighborhood Hits	808	Target Neighborhood Hits	233	Shared Neighborhood Hits	159
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TDGF1_HUMAN
NC score	0.210991 (rank : 334)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	808	Target Neighborhood Hits	132	Shared Neighborhood Hits	110
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

FA10_MOUSE
NC score	0.209624 (rank : 335)	θ value	1.38821 (rank : 563)
Query Neighborhood Hits	808	Target Neighborhood Hits	435	Shared Neighborhood Hits	240
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

PERT_HUMAN
NC score	0.208568 (rank : 336)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	808	Target Neighborhood Hits	221	Shared Neighborhood Hits	151
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

EMR3_HUMAN
NC score	0.208303 (rank : 337)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	808	Target Neighborhood Hits	245	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

MT4_HUMAN
NC score	0.208183 (rank : 338)	θ value	0.0193708 (rank : 318)
Query Neighborhood Hits	808	Target Neighborhood Hits	83	Shared Neighborhood Hits	69
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

SUSD2_HUMAN
NC score	0.208134 (rank : 339)	θ value	2.88788e-06 (rank : 132)
Query Neighborhood Hits	808	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

TDGF2_HUMAN
NC score	0.207304 (rank : 340)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	808	Target Neighborhood Hits	131	Shared Neighborhood Hits	106
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

NET1_MOUSE
NC score	0.207292 (rank : 341)	θ value	θ > 10 (rank : 1013)
Query Neighborhood Hits	808	Target Neighborhood Hits	151	Shared Neighborhood Hits	114
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

LCE5A_HUMAN
NC score	0.206598 (rank : 342)	θ value	2.36792 (rank : 614)
Query Neighborhood Hits	808	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

FA10_HUMAN
NC score	0.206139 (rank : 343)	θ value	0.813845 (rank : 515)
Query Neighborhood Hits	808	Target Neighborhood Hits	431	Shared Neighborhood Hits	240
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

TLL2_HUMAN
NC score	0.205633 (rank : 344)	θ value	0.279714 (rank : 455)
Query Neighborhood Hits	808	Target Neighborhood Hits	241	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

ZNFX1_MOUSE
NC score	0.205488 (rank : 345)	θ value	0.365318 (rank : 477)
Query Neighborhood Hits	808	Target Neighborhood Hits	407	Shared Neighborhood Hits	169
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

TLL1_MOUSE
NC score	0.205444 (rank : 346)	θ value	5.27518 (rank : 708)
Query Neighborhood Hits	808	Target Neighborhood Hits	237	Shared Neighborhood Hits	159
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

KR122_HUMAN
NC score	0.203875 (rank : 347)	θ value	0.163984 (rank : 417)
Query Neighborhood Hits	808	Target Neighborhood Hits	97	Shared Neighborhood Hits	75
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

CRDL1_HUMAN
NC score	0.203399 (rank : 348)	θ value	0.125558 (rank : 400)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

FST_MOUSE
NC score	0.203273 (rank : 349)	θ value	0.00102713 (rank : 229)
Query Neighborhood Hits	808	Target Neighborhood Hits	146	Shared Neighborhood Hits	92
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

TLL2_MOUSE
NC score	0.202706 (rank : 350)	θ value	1.81305 (rank : 594)
Query Neighborhood Hits	808	Target Neighborhood Hits	240	Shared Neighborhood Hits	159
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_HUMAN
NC score	0.201243 (rank : 351)	θ value	4.03905 (rank : 677)
Query Neighborhood Hits	808	Target Neighborhood Hits	236	Shared Neighborhood Hits	155
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

NRX1A_HUMAN
NC score	0.199834 (rank : 352)	θ value	0.0193708 (rank : 320)
Query Neighborhood Hits	808	Target Neighborhood Hits	170	Shared Neighborhood Hits	132
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

PGCB_HUMAN
NC score	0.199728 (rank : 353)	θ value	0.00869519 (rank : 299)
Query Neighborhood Hits	808	Target Neighborhood Hits	478	Shared Neighborhood Hits	199
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

LCE2D_HUMAN
NC score	0.199599 (rank : 354)	θ value	0.813845 (rank : 516)
Query Neighborhood Hits	808	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

NRX1A_MOUSE
NC score	0.199314 (rank : 355)	θ value	0.0193708 (rank : 321)
Query Neighborhood Hits	808	Target Neighborhood Hits	164	Shared Neighborhood Hits	131
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

LRP3_HUMAN
NC score	0.199210 (rank : 356)	θ value	3.0926 (rank : 640)
Query Neighborhood Hits	808	Target Neighborhood Hits	280	Shared Neighborhood Hits	137
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

FSTL3_MOUSE
NC score	0.198611 (rank : 357)	θ value	0.00665767 (rank : 283)
Query Neighborhood Hits	808	Target Neighborhood Hits	152	Shared Neighborhood Hits	104
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_HUMAN
NC score	0.197800 (rank : 358)	θ value	0.00298849 (rank : 259)
Query Neighborhood Hits	808	Target Neighborhood Hits	162	Shared Neighborhood Hits	108
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FA9_HUMAN
NC score	0.197495 (rank : 359)	θ value	0.0736092 (rank : 378)
Query Neighborhood Hits	808	Target Neighborhood Hits	421	Shared Neighborhood Hits	232
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

TNR9_HUMAN
NC score	0.196475 (rank : 360)	θ value	0.00665767 (rank : 287)
Query Neighborhood Hits	808	Target Neighborhood Hits	166	Shared Neighborhood Hits	118
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

PROC_MOUSE
NC score	0.196042 (rank : 361)	θ value	0.62314 (rank : 505)
Query Neighborhood Hits	808	Target Neighborhood Hits	426	Shared Neighborhood Hits	244
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

CORIN_HUMAN
NC score	0.195429 (rank : 362)	θ value	3.77169e-06 (rank : 134)
Query Neighborhood Hits	808	Target Neighborhood Hits	453	Shared Neighborhood Hits	214
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

PERT_MOUSE
NC score	0.195015 (rank : 363)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	808	Target Neighborhood Hits	221	Shared Neighborhood Hits	145
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

CD320_HUMAN
NC score	0.192804 (rank : 364)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	808	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

MAP4_HUMAN
NC score	0.192526 (rank : 365)	θ value	6.85773e-16 (rank : 38)
Query Neighborhood Hits	808	Target Neighborhood Hits	428	Shared Neighborhood Hits	67
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MEP1A_MOUSE
NC score	0.190558 (rank : 366)	θ value	1.06291 (rank : 549)
Query Neighborhood Hits	808	Target Neighborhood Hits	166	Shared Neighborhood Hits	146
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MFGM_HUMAN
NC score	0.190437 (rank : 367)	θ value	0.0961366 (rank : 391)
Query Neighborhood Hits	808	Target Neighborhood Hits	150	Shared Neighborhood Hits	126
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

ADAM8_MOUSE
NC score	0.190345 (rank : 368)	θ value	0.0431538 (rank : 346)
Query Neighborhood Hits	808	Target Neighborhood Hits	326	Shared Neighborhood Hits	231
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

CNTP2_MOUSE
NC score	0.190049 (rank : 369)	θ value	1.06291 (rank : 536)
Query Neighborhood Hits	808	Target Neighborhood Hits	194	Shared Neighborhood Hits	147
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_HUMAN
NC score	0.189802 (rank : 370)	θ value	1.06291 (rank : 535)
Query Neighborhood Hits	808	Target Neighborhood Hits	199	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

FST_HUMAN
NC score	0.189570 (rank : 371)	θ value	0.00228821 (rank : 254)
Query Neighborhood Hits	808	Target Neighborhood Hits	129	Shared Neighborhood Hits	74
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

WISP2_MOUSE
NC score	0.188532 (rank : 372)	θ value	0.00298849 (rank : 262)
Query Neighborhood Hits	808	Target Neighborhood Hits	129	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

NRX2A_HUMAN
NC score	0.188338 (rank : 373)	θ value	0.0736092 (rank : 382)
Query Neighborhood Hits	808	Target Neighborhood Hits	614	Shared Neighborhood Hits	157
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

LCE2B_HUMAN
NC score	0.188278 (rank : 374)	θ value	0.62314 (rank : 502)
Query Neighborhood Hits	808	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

NOV_HUMAN
NC score	0.187097 (rank : 375)	θ value	0.0193708 (rank : 319)
Query Neighborhood Hits	808	Target Neighborhood Hits	128	Shared Neighborhood Hits	84
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

CNTP4_MOUSE
NC score	0.186874 (rank : 376)	θ value	0.163984 (rank : 411)
Query Neighborhood Hits	808	Target Neighborhood Hits	193	Shared Neighborhood Hits	147
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

HGFA_MOUSE
NC score	0.185888 (rank : 377)	θ value	0.000602161 (rank : 213)
Query Neighborhood Hits	808	Target Neighborhood Hits	419	Shared Neighborhood Hits	213
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

NRX3A_HUMAN
NC score	0.184973 (rank : 378)	θ value	0.365318 (rank : 472)
Query Neighborhood Hits	808	Target Neighborhood Hits	164	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PGCA_HUMAN
NC score	0.184373 (rank : 379)	θ value	0.0563607 (rank : 369)
Query Neighborhood Hits	808	Target Neighborhood Hits	821	Shared Neighborhood Hits	223
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

FA7_HUMAN
NC score	0.184357 (rank : 380)	θ value	0.163984 (rank : 413)
Query Neighborhood Hits	808	Target Neighborhood Hits	404	Shared Neighborhood Hits	219
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

MAP4_MOUSE
NC score	0.184251 (rank : 381)	θ value	1.80886e-08 (rank : 86)
Query Neighborhood Hits	808	Target Neighborhood Hits	409	Shared Neighborhood Hits	65
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CO6_HUMAN
NC score	0.184078 (rank : 382)	θ value	2.36792 (rank : 608)
Query Neighborhood Hits	808	Target Neighborhood Hits	331	Shared Neighborhood Hits	185
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

WISP2_HUMAN
NC score	0.183954 (rank : 383)	θ value	0.0252991 (rank : 337)
Query Neighborhood Hits	808	Target Neighborhood Hits	126	Shared Neighborhood Hits	76
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

MEP1A_HUMAN
NC score	0.183838 (rank : 384)	θ value	1.06291 (rank : 548)
Query Neighborhood Hits	808	Target Neighborhood Hits	162	Shared Neighborhood Hits	141
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

KR123_HUMAN
NC score	0.183822 (rank : 385)	θ value	6.88961 (rank : 737)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	64
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

ADAM8_HUMAN
NC score	0.183530 (rank : 386)	θ value	1.06291 (rank : 527)
Query Neighborhood Hits	808	Target Neighborhood Hits	327	Shared Neighborhood Hits	241
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

CYR61_MOUSE
NC score	0.183350 (rank : 387)	θ value	0.00134147 (rank : 235)
Query Neighborhood Hits	808	Target Neighborhood Hits	156	Shared Neighborhood Hits	101
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

VEGFC_HUMAN
NC score	0.182827 (rank : 388)	θ value	0.0113563 (rank : 305)
Query Neighborhood Hits	808	Target Neighborhood Hits	128	Shared Neighborhood Hits	105
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

TNR8_HUMAN
NC score	0.182700 (rank : 389)	θ value	0.00134147 (rank : 239)
Query Neighborhood Hits	808	Target Neighborhood Hits	198	Shared Neighborhood Hits	114
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

CYR61_HUMAN
NC score	0.182356 (rank : 390)	θ value	0.000461057 (rank : 208)
Query Neighborhood Hits	808	Target Neighborhood Hits	159	Shared Neighborhood Hits	105
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

KR111_HUMAN
NC score	0.182225 (rank : 391)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	808	Target Neighborhood Hits	90	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

CNTP4_HUMAN
NC score	0.182103 (rank : 392)	θ value	0.279714 (rank : 449)
Query Neighborhood Hits	808	Target Neighborhood Hits	187	Shared Neighborhood Hits	131
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

HGFA_HUMAN
NC score	0.180614 (rank : 393)	θ value	0.21417 (rank : 429)
Query Neighborhood Hits	808	Target Neighborhood Hits	436	Shared Neighborhood Hits	212
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

CNTP3_HUMAN
NC score	0.180331 (rank : 394)	θ value	0.0961366 (rank : 386)
Query Neighborhood Hits	808	Target Neighborhood Hits	195	Shared Neighborhood Hits	138
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

MATN1_HUMAN
NC score	0.179776 (rank : 395)	θ value	θ > 10 (rank : 995)
Query Neighborhood Hits	808	Target Neighborhood Hits	191	Shared Neighborhood Hits	118
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
NC score	0.179702 (rank : 396)	θ value	θ > 10 (rank : 996)
Query Neighborhood Hits	808	Target Neighborhood Hits	186	Shared Neighborhood Hits	116
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

CORIN_MOUSE
NC score	0.179467 (rank : 397)	θ value	2.44474e-05 (rank : 155)
Query Neighborhood Hits	808	Target Neighborhood Hits	451	Shared Neighborhood Hits	208
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

ADA15_MOUSE
NC score	0.179259 (rank : 398)	θ value	1.81305 (rank : 581)
Query Neighborhood Hits	808	Target Neighborhood Hits	324	Shared Neighborhood Hits	234
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

CLC14_MOUSE
NC score	0.178924 (rank : 399)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	808	Target Neighborhood Hits	120	Shared Neighborhood Hits	95
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

ADA17_HUMAN
NC score	0.177917 (rank : 400)	θ value	0.0193708 (rank : 313)
Query Neighborhood Hits	808	Target Neighborhood Hits	223	Shared Neighborhood Hits	172
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

NACAM_MOUSE
NC score	0.177798 (rank : 401)	θ value	1.74391e-19 (rank : 30)
Query Neighborhood Hits	808	Target Neighborhood Hits	1866	Shared Neighborhood Hits	169
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

FAT2_HUMAN
NC score	0.176701 (rank : 402)	θ value	0.0330416 (rank : 342)
Query Neighborhood Hits	808	Target Neighborhood Hits	507	Shared Neighborhood Hits	218
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

CNTP1_HUMAN
NC score	0.176009 (rank : 403)	θ value	0.00390308 (rank : 263)
Query Neighborhood Hits	808	Target Neighborhood Hits	196	Shared Neighborhood Hits	127
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

MDC1_HUMAN
NC score	0.175982 (rank : 404)	θ value	5.8054e-15 (rank : 41)
Query Neighborhood Hits	808	Target Neighborhood Hits	1446	Shared Neighborhood Hits	121
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TNR16_MOUSE
NC score	0.175592 (rank : 405)	θ value	θ > 10 (rank : 1106)
Query Neighborhood Hits	808	Target Neighborhood Hits	178	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

WISP1_MOUSE
NC score	0.174840 (rank : 406)	θ value	0.0563607 (rank : 372)
Query Neighborhood Hits	808	Target Neighborhood Hits	123	Shared Neighborhood Hits	81
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

ESM1_HUMAN
NC score	0.174831 (rank : 407)	θ value	4.03905 (rank : 660)
Query Neighborhood Hits	808	Target Neighborhood Hits	110	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

TNR8_MOUSE
NC score	0.174813 (rank : 408)	θ value	0.125558 (rank : 409)
Query Neighborhood Hits	808	Target Neighborhood Hits	208	Shared Neighborhood Hits	110
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

RELN_MOUSE
NC score	0.173294 (rank : 409)	θ value	1.81305 (rank : 592)
Query Neighborhood Hits	808	Target Neighborhood Hits	235	Shared Neighborhood Hits	179
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

FA12_HUMAN
NC score	0.173207 (rank : 410)	θ value	0.00298849 (rank : 258)
Query Neighborhood Hits	808	Target Neighborhood Hits	425	Shared Neighborhood Hits	209
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

LRP10_MOUSE
NC score	0.172714 (rank : 411)	θ value	0.279714 (rank : 452)
Query Neighborhood Hits	808	Target Neighborhood Hits	169	Shared Neighborhood Hits	99
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

CO7_HUMAN
NC score	0.171843 (rank : 412)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	808	Target Neighborhood Hits	278	Shared Neighborhood Hits	160
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CK024_MOUSE
NC score	0.171657 (rank : 413)	θ value	1.09739e-05 (rank : 146)
Query Neighborhood Hits	808	Target Neighborhood Hits	307	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CNTP1_MOUSE
NC score	0.171171 (rank : 414)	θ value	0.00509761 (rank : 268)
Query Neighborhood Hits	808	Target Neighborhood Hits	183	Shared Neighborhood Hits	122
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

PROC_HUMAN
NC score	0.171092 (rank : 415)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	808	Target Neighborhood Hits	406	Shared Neighborhood Hits	227
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

TNR16_HUMAN
NC score	0.170839 (rank : 416)	θ value	5.27518 (rank : 709)
Query Neighborhood Hits	808	Target Neighborhood Hits	183	Shared Neighborhood Hits	127
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

MT3_HUMAN
NC score	0.170521 (rank : 417)	θ value	θ > 10 (rank : 1003)
Query Neighborhood Hits	808	Target Neighborhood Hits	82	Shared Neighborhood Hits	67
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

ADA15_HUMAN
NC score	0.170410 (rank : 418)	θ value	0.279714 (rank : 446)
Query Neighborhood Hits	808	Target Neighborhood Hits	288	Shared Neighborhood Hits	216
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

CTGF_HUMAN
NC score	0.169860 (rank : 419)	θ value	1.06291 (rank : 537)
Query Neighborhood Hits	808	Target Neighborhood Hits	128	Shared Neighborhood Hits	88
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

RELN_HUMAN
NC score	0.169511 (rank : 420)	θ value	0.47712 (rank : 489)
Query Neighborhood Hits	808	Target Neighborhood Hits	233	Shared Neighborhood Hits	176
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

ADA11_MOUSE
NC score	0.169181 (rank : 421)	θ value	3.0926 (rank : 632)
Query Neighborhood Hits	808	Target Neighborhood Hits	263	Shared Neighborhood Hits	204
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_HUMAN
NC score	0.167596 (rank : 422)	θ value	6.88961 (rank : 716)
Query Neighborhood Hits	808	Target Neighborhood Hits	259	Shared Neighborhood Hits	203
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

LRP10_HUMAN
NC score	0.167113 (rank : 423)	θ value	θ > 10 (rank : 984)
Query Neighborhood Hits	808	Target Neighborhood Hits	197	Shared Neighborhood Hits	105
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

NOV_MOUSE
NC score	0.166637 (rank : 424)	θ value	0.0252991 (rank : 335)
Query Neighborhood Hits	808	Target Neighborhood Hits	130	Shared Neighborhood Hits	85
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

CLC14_HUMAN
NC score	0.166504 (rank : 425)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	808	Target Neighborhood Hits	143	Shared Neighborhood Hits	98
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

LRP12_HUMAN
NC score	0.166047 (rank : 426)	θ value	θ > 10 (rank : 987)
Query Neighborhood Hits	808	Target Neighborhood Hits	205	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

ADA23_HUMAN
NC score	0.165807 (rank : 427)	θ value	1.06291 (rank : 526)
Query Neighborhood Hits	808	Target Neighborhood Hits	235	Shared Neighborhood Hits	194
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

CTGF_MOUSE
NC score	0.165486 (rank : 428)	θ value	1.38821 (rank : 560)
Query Neighborhood Hits	808	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

ST14_MOUSE
NC score	0.165306 (rank : 429)	θ value	0.000270298 (rank : 199)
Query Neighborhood Hits	808	Target Neighborhood Hits	419	Shared Neighborhood Hits	197
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

MMRN1_HUMAN
NC score	0.164975 (rank : 430)	θ value	0.163984 (rank : 419)
Query Neighborhood Hits	808	Target Neighborhood Hits	636	Shared Neighborhood Hits	155
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

SPR2D_MOUSE
NC score	0.163996 (rank : 431)	θ value	0.0961366 (rank : 392)
Query Neighborhood Hits	808	Target Neighborhood Hits	61	Shared Neighborhood Hits	35
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

LRP12_MOUSE
NC score	0.163651 (rank : 432)	θ value	θ > 10 (rank : 988)
Query Neighborhood Hits	808	Target Neighborhood Hits	180	Shared Neighborhood Hits	98
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

GP112_HUMAN
NC score	0.162805 (rank : 433)	θ value	1.68911e-14 (rank : 42)
Query Neighborhood Hits	808	Target Neighborhood Hits	441	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

TNR14_HUMAN
NC score	0.162387 (rank : 434)	θ value	0.0113563 (rank : 304)
Query Neighborhood Hits	808	Target Neighborhood Hits	149	Shared Neighborhood Hits	101
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

ADA23_MOUSE
NC score	0.161866 (rank : 435)	θ value	6.88961 (rank : 717)
Query Neighborhood Hits	808	Target Neighborhood Hits	245	Shared Neighborhood Hits	209
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

KR261_HUMAN
NC score	0.160921 (rank : 436)	θ value	0.21417 (rank : 432)
Query Neighborhood Hits	808	Target Neighborhood Hits	65	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

ADA19_HUMAN
NC score	0.160785 (rank : 437)	θ value	0.0563607 (rank : 364)
Query Neighborhood Hits	808	Target Neighborhood Hits	381	Shared Neighborhood Hits	203
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

WISP1_HUMAN
NC score	0.160313 (rank : 438)	θ value	0.47712 (rank : 494)
Query Neighborhood Hits	808	Target Neighborhood Hits	121	Shared Neighborhood Hits	81
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

ADA18_MOUSE
NC score	0.160270 (rank : 439)	θ value	3.0926 (rank : 633)
Query Neighborhood Hits	808	Target Neighborhood Hits	227	Shared Neighborhood Hits	192
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA19_MOUSE
NC score	0.159763 (rank : 440)	θ value	1.38821 (rank : 558)
Query Neighborhood Hits	808	Target Neighborhood Hits	315	Shared Neighborhood Hits	209
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

MT3_MOUSE
NC score	0.159429 (rank : 441)	θ value	θ > 10 (rank : 1004)
Query Neighborhood Hits	808	Target Neighborhood Hits	68	Shared Neighborhood Hits	58
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

TNR9_MOUSE
NC score	0.159365 (rank : 442)	θ value	1.81305 (rank : 596)
Query Neighborhood Hits	808	Target Neighborhood Hits	137	Shared Neighborhood Hits	103
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

ST14_HUMAN
NC score	0.159102 (rank : 443)	θ value	0.00175202 (rank : 250)
Query Neighborhood Hits	808	Target Neighborhood Hits	409	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

MDC1_MOUSE
NC score	0.158610 (rank : 444)	θ value	1.43324e-05 (rank : 150)
Query Neighborhood Hits	808	Target Neighborhood Hits	998	Shared Neighborhood Hits	103
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

ADAM9_MOUSE
NC score	0.158578 (rank : 445)	θ value	2.36792 (rank : 603)
Query Neighborhood Hits	808	Target Neighborhood Hits	325	Shared Neighborhood Hits	216
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

FA7_MOUSE
NC score	0.157979 (rank : 446)	θ value	0.125558 (rank : 402)
Query Neighborhood Hits	808	Target Neighborhood Hits	374	Shared Neighborhood Hits	194
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

EMR4_MOUSE
NC score	0.157038 (rank : 447)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	808	Target Neighborhood Hits	191	Shared Neighborhood Hits	109
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

ESM1_MOUSE
NC score	0.156625 (rank : 448)	θ value	1.38821 (rank : 562)
Query Neighborhood Hits	808	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

TIE1_HUMAN
NC score	0.156244 (rank : 449)	θ value	0.125558 (rank : 408)
Query Neighborhood Hits	808	Target Neighborhood Hits	1241	Shared Neighborhood Hits	303
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

ADAM7_HUMAN
NC score	0.156176 (rank : 450)	θ value	5.44631e-05 (rank : 166)
Query Neighborhood Hits	808	Target Neighborhood Hits	221	Shared Neighborhood Hits	187
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

TIE1_MOUSE
NC score	0.155987 (rank : 451)	θ value	0.00390308 (rank : 266)
Query Neighborhood Hits	808	Target Neighborhood Hits	1266	Shared Neighborhood Hits	302
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

PGH2_MOUSE
NC score	0.155963 (rank : 452)	θ value	0.0193708 (rank : 324)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	101
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PHXR5_MOUSE
NC score	0.153700 (rank : 453)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	70
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

ADA17_MOUSE
NC score	0.152811 (rank : 454)	θ value	0.0252991 (rank : 325)
Query Neighborhood Hits	808	Target Neighborhood Hits	201	Shared Neighborhood Hits	160
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA33_HUMAN
NC score	0.152648 (rank : 455)	θ value	1.38821 (rank : 559)
Query Neighborhood Hits	808	Target Neighborhood Hits	264	Shared Neighborhood Hits	182
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADM1A_MOUSE
NC score	0.152409 (rank : 456)	θ value	0.000786445 (rank : 220)
Query Neighborhood Hits	808	Target Neighborhood Hits	230	Shared Neighborhood Hits	193
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

CO8B_MOUSE
NC score	0.152079 (rank : 457)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	808	Target Neighborhood Hits	224	Shared Neighborhood Hits	132
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADA33_MOUSE
NC score	0.149944 (rank : 458)	θ value	0.125558 (rank : 398)
Query Neighborhood Hits	808	Target Neighborhood Hits	231	Shared Neighborhood Hits	180
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA10_HUMAN
NC score	0.149360 (rank : 459)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	808	Target Neighborhood Hits	189	Shared Neighborhood Hits	150
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADAM9_HUMAN
NC score	0.148763 (rank : 460)	θ value	4.03905 (rank : 653)
Query Neighborhood Hits	808	Target Neighborhood Hits	243	Shared Neighborhood Hits	196
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADA10_MOUSE
NC score	0.146765 (rank : 461)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	808	Target Neighborhood Hits	194	Shared Neighborhood Hits	150
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

VEGFC_MOUSE
NC score	0.146197 (rank : 462)	θ value	0.47712 (rank : 493)
Query Neighborhood Hits	808	Target Neighborhood Hits	119	Shared Neighborhood Hits	97
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

SON_MOUSE
NC score	0.144881 (rank : 463)	θ value	7.59969e-07 (rank : 119)
Query Neighborhood Hits	808	Target Neighborhood Hits	957	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

MUC13_HUMAN
NC score	0.144497 (rank : 464)	θ value	θ > 10 (rank : 1005)
Query Neighborhood Hits	808	Target Neighborhood Hits	164	Shared Neighborhood Hits	115
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MT1_MOUSE
NC score	0.144329 (rank : 465)	θ value	0.365318 (rank : 470)
Query Neighborhood Hits	808	Target Neighborhood Hits	72	Shared Neighborhood Hits	63
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

ADAM2_MOUSE
NC score	0.143342 (rank : 466)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	808	Target Neighborhood Hits	209	Shared Neighborhood Hits	165
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

SPR2I_MOUSE
NC score	0.143248 (rank : 467)	θ value	0.0961366 (rank : 394)
Query Neighborhood Hits	808	Target Neighborhood Hits	45	Shared Neighborhood Hits	26
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

RSPO3_HUMAN
NC score	0.142681 (rank : 468)	θ value	4.03905 (rank : 674)
Query Neighborhood Hits	808	Target Neighborhood Hits	128	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

ADA22_MOUSE
NC score	0.139862 (rank : 469)	θ value	0.47712 (rank : 478)
Query Neighborhood Hits	808	Target Neighborhood Hits	225	Shared Neighborhood Hits	176
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA12_HUMAN
NC score	0.139430 (rank : 470)	θ value	0.21417 (rank : 426)
Query Neighborhood Hits	808	Target Neighborhood Hits	224	Shared Neighborhood Hits	158
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA32_HUMAN
NC score	0.138910 (rank : 471)	θ value	0.00134147 (rank : 234)
Query Neighborhood Hits	808	Target Neighborhood Hits	216	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADM1B_MOUSE
NC score	0.138867 (rank : 472)	θ value	0.0431538 (rank : 347)
Query Neighborhood Hits	808	Target Neighborhood Hits	236	Shared Neighborhood Hits	165
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA30_HUMAN
NC score	0.138419 (rank : 473)	θ value	0.365318 (rank : 460)
Query Neighborhood Hits	808	Target Neighborhood Hits	391	Shared Neighborhood Hits	154
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

TNR7_HUMAN
NC score	0.138301 (rank : 474)	θ value	0.163984 (rank : 424)
Query Neighborhood Hits	808	Target Neighborhood Hits	120	Shared Neighborhood Hits	91
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

ADA28_HUMAN
NC score	0.138129 (rank : 475)	θ value	4.03905 (rank : 652)
Query Neighborhood Hits	808	Target Neighborhood Hits	244	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

TIE2_MOUSE
NC score	0.137876 (rank : 476)	θ value	1.38821 (rank : 578)
Query Neighborhood Hits	808	Target Neighborhood Hits	1204	Shared Neighborhood Hits	289
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

ADA28_MOUSE
NC score	0.137853 (rank : 477)	θ value	0.279714 (rank : 448)
Query Neighborhood Hits	808	Target Neighborhood Hits	241	Shared Neighborhood Hits	184
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

MKS3_HUMAN
NC score	0.137268 (rank : 478)	θ value	0.47712 (rank : 486)
Query Neighborhood Hits	808	Target Neighborhood Hits	79	Shared Neighborhood Hits	68
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

NRP1_HUMAN
NC score	0.136807 (rank : 479)	θ value	0.000121331 (rank : 181)
Query Neighborhood Hits	808	Target Neighborhood Hits	119	Shared Neighborhood Hits	53
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRG4_HUMAN
NC score	0.136554 (rank : 480)	θ value	θ > 10 (rank : 1026)
Query Neighborhood Hits	808	Target Neighborhood Hits	85	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

PGH2_HUMAN
NC score	0.136086 (rank : 481)	θ value	0.62314 (rank : 504)
Query Neighborhood Hits	808	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

MT2_MOUSE
NC score	0.135962 (rank : 482)	θ value	1.06291 (rank : 550)
Query Neighborhood Hits	808	Target Neighborhood Hits	81	Shared Neighborhood Hits	70
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

TNR6B_HUMAN
NC score	0.135644 (rank : 483)	θ value	8.40245e-06 (rank : 145)
Query Neighborhood Hits	808	Target Neighborhood Hits	103	Shared Neighborhood Hits	67
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

ADA18_HUMAN
NC score	0.135569 (rank : 484)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	808	Target Neighborhood Hits	184	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

TIE2_HUMAN
NC score	0.135070 (rank : 485)	θ value	0.47712 (rank : 492)
Query Neighborhood Hits	808	Target Neighborhood Hits	1192	Shared Neighborhood Hits	280
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

NRP1_MOUSE
NC score	0.133992 (rank : 486)	θ value	5.44631e-05 (rank : 170)
Query Neighborhood Hits	808	Target Neighborhood Hits	120	Shared Neighborhood Hits	52
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
NC score	0.133341 (rank : 487)	θ value	1.29631e-06 (rank : 125)
Query Neighborhood Hits	808	Target Neighborhood Hits	120	Shared Neighborhood Hits	53
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

SMDF_HUMAN
NC score	0.133053 (rank : 488)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	808	Target Neighborhood Hits	117	Shared Neighborhood Hits	70
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

ADA24_MOUSE
NC score	0.133039 (rank : 489)	θ value	0.0252991 (rank : 326)
Query Neighborhood Hits	808	Target Neighborhood Hits	230	Shared Neighborhood Hits	183
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

SPR2H_MOUSE
NC score	0.133007 (rank : 490)	θ value	0.0961366 (rank : 393)
Query Neighborhood Hits	808	Target Neighborhood Hits	82	Shared Neighborhood Hits	42
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2E_MOUSE
NC score	0.132932 (rank : 491)	θ value	0.125558 (rank : 407)
Query Neighborhood Hits	808	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

MKS3_MOUSE
NC score	0.132818 (rank : 492)	θ value	0.125558 (rank : 404)
Query Neighborhood Hits	808	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

PAPPA_HUMAN
NC score	0.132155 (rank : 493)	θ value	0.0193708 (rank : 322)
Query Neighborhood Hits	808	Target Neighborhood Hits	161	Shared Neighborhood Hits	83
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

ADA22_HUMAN
NC score	0.132140 (rank : 494)	θ value	1.81305 (rank : 582)
Query Neighborhood Hits	808	Target Neighborhood Hits	211	Shared Neighborhood Hits	165
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA12_MOUSE
NC score	0.131460 (rank : 495)	θ value	0.0330416 (rank : 339)
Query Neighborhood Hits	808	Target Neighborhood Hits	474	Shared Neighborhood Hits	165
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA32_MOUSE
NC score	0.131339 (rank : 496)	θ value	0.47712 (rank : 479)
Query Neighborhood Hits	808	Target Neighborhood Hits	219	Shared Neighborhood Hits	179
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

TARSH_HUMAN
NC score	0.131169 (rank : 497)	θ value	0.0961366 (rank : 395)
Query Neighborhood Hits	808	Target Neighborhood Hits	768	Shared Neighborhood Hits	107
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

SELPL_MOUSE
NC score	0.131132 (rank : 498)	θ value	0.00020696 (rank : 194)
Query Neighborhood Hits	808	Target Neighborhood Hits	588	Shared Neighborhood Hits	76
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SPR2G_MOUSE
NC score	0.130764 (rank : 499)	θ value	0.62314 (rank : 507)
Query Neighborhood Hits	808	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

ADA21_MOUSE
NC score	0.130216 (rank : 500)	θ value	0.163984 (rank : 410)
Query Neighborhood Hits	808	Target Neighborhood Hits	172	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ASTN_HUMAN
NC score	0.130114 (rank : 501)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	808	Target Neighborhood Hits	105	Shared Neighborhood Hits	82
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

PGH1_MOUSE
NC score	0.129840 (rank : 502)	θ value	1.38821 (rank : 574)
Query Neighborhood Hits	808	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

CO9_MOUSE
NC score	0.129674 (rank : 503)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	808	Target Neighborhood Hits	153	Shared Neighborhood Hits	95
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

ADAM2_HUMAN
NC score	0.129492 (rank : 504)	θ value	2.36792 (rank : 602)
Query Neighborhood Hits	808	Target Neighborhood Hits	175	Shared Neighborhood Hits	143
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

CO8A_HUMAN
NC score	0.129297 (rank : 505)	θ value	2.36792 (rank : 609)
Query Neighborhood Hits	808	Target Neighborhood Hits	200	Shared Neighborhood Hits	119
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

RSPO4_HUMAN
NC score	0.128546 (rank : 506)	θ value	3.0926 (rank : 644)
Query Neighborhood Hits	808	Target Neighborhood Hits	110	Shared Neighborhood Hits	86
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

ADAM7_MOUSE
NC score	0.128533 (rank : 507)	θ value	0.0330416 (rank : 340)
Query Neighborhood Hits	808	Target Neighborhood Hits	200	Shared Neighborhood Hits	155
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADA25_MOUSE
NC score	0.127607 (rank : 508)	θ value	0.279714 (rank : 447)
Query Neighborhood Hits	808	Target Neighborhood Hits	213	Shared Neighborhood Hits	164
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

CT127_HUMAN
NC score	0.126901 (rank : 509)	θ value	8.99809 (rank : 770)
Query Neighborhood Hits	808	Target Neighborhood Hits	67	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

TNR21_MOUSE
NC score	0.126604 (rank : 510)	θ value	0.0148317 (rank : 311)
Query Neighborhood Hits	808	Target Neighborhood Hits	108	Shared Neighborhood Hits	66
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

CK024_HUMAN
NC score	0.126593 (rank : 511)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	808	Target Neighborhood Hits	408	Shared Neighborhood Hits	67
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

SPR2B_MOUSE
NC score	0.126376 (rank : 512)	θ value	0.0563607 (rank : 370)
Query Neighborhood Hits	808	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

ASTN_MOUSE
NC score	0.126279 (rank : 513)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	808	Target Neighborhood Hits	98	Shared Neighborhood Hits	78
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

MT1B_HUMAN
NC score	0.125982 (rank : 514)	θ value	6.88961 (rank : 743)
Query Neighborhood Hits	808	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

CO8B_HUMAN
NC score	0.125859 (rank : 515)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	808	Target Neighborhood Hits	199	Shared Neighborhood Hits	106
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

LCE3C_HUMAN
NC score	0.125847 (rank : 516)	θ value	1.38821 (rank : 570)
Query Neighborhood Hits	808	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

CO9_HUMAN
NC score	0.125677 (rank : 517)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	808	Target Neighborhood Hits	147	Shared Neighborhood Hits	89
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

C1RA_MOUSE
NC score	0.125585 (rank : 518)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	808	Target Neighborhood Hits	379	Shared Neighborhood Hits	154
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

MUC7_HUMAN
NC score	0.125391 (rank : 519)	θ value	θ > 10 (rank : 1007)
Query Neighborhood Hits	808	Target Neighborhood Hits	538	Shared Neighborhood Hits	100
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MEP1B_MOUSE
NC score	0.125242 (rank : 520)	θ value	θ > 10 (rank : 999)
Query Neighborhood Hits	808	Target Neighborhood Hits	127	Shared Neighborhood Hits	95
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

NRG1_HUMAN
NC score	0.125240 (rank : 521)	θ value	2.36792 (rank : 620)
Query Neighborhood Hits	808	Target Neighborhood Hits	285	Shared Neighborhood Hits	97
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

MT1A_HUMAN
NC score	0.124798 (rank : 522)	θ value	2.36792 (rank : 616)
Query Neighborhood Hits	808	Target Neighborhood Hits	74	Shared Neighborhood Hits	64
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

C1RB_MOUSE
NC score	0.124010 (rank : 523)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	808	Target Neighborhood Hits	380	Shared Neighborhood Hits	154
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

KR131_HUMAN
NC score	0.123914 (rank : 524)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	808	Target Neighborhood Hits	123	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

RSPO3_MOUSE
NC score	0.123580 (rank : 525)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	808	Target Neighborhood Hits	120	Shared Neighborhood Hits	79
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

ADA21_HUMAN
NC score	0.123147 (rank : 526)	θ value	8.99809 (rank : 762)
Query Neighborhood Hits	808	Target Neighborhood Hits	181	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

TNR4_MOUSE
NC score	0.123107 (rank : 527)	θ value	θ > 10 (rank : 1114)
Query Neighborhood Hits	808	Target Neighborhood Hits	137	Shared Neighborhood Hits	90
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

SPR2F_MOUSE
NC score	0.122813 (rank : 528)	θ value	0.21417 (rank : 438)
Query Neighborhood Hits	808	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

PAPPA_MOUSE
NC score	0.122322 (rank : 529)	θ value	0.21417 (rank : 436)
Query Neighborhood Hits	808	Target Neighborhood Hits	153	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

LR37A_HUMAN
NC score	0.122179 (rank : 530)	θ value	3.41135e-07 (rank : 111)
Query Neighborhood Hits	808	Target Neighborhood Hits	720	Shared Neighborhood Hits	97
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

CO8A_MOUSE
NC score	0.121983 (rank : 531)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	808	Target Neighborhood Hits	182	Shared Neighborhood Hits	101
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

NRG2_MOUSE
NC score	0.121980 (rank : 532)	θ value	θ > 10 (rank : 1023)
Query Neighborhood Hits	808	Target Neighborhood Hits	392	Shared Neighborhood Hits	121
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG4_MOUSE
NC score	0.121578 (rank : 533)	θ value	θ > 10 (rank : 1027)
Query Neighborhood Hits	808	Target Neighborhood Hits	79	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

PRG4_HUMAN
NC score	0.120612 (rank : 534)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	808	Target Neighborhood Hits	764	Shared Neighborhood Hits	132
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TNR23_MOUSE
NC score	0.120368 (rank : 535)	θ value	θ > 10 (rank : 1111)
Query Neighborhood Hits	808	Target Neighborhood Hits	114	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

MUC1_MOUSE
NC score	0.120179 (rank : 536)	θ value	θ > 10 (rank : 1006)
Query Neighborhood Hits	808	Target Neighborhood Hits	388	Shared Neighborhood Hits	72
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NRP2_MOUSE
NC score	0.119305 (rank : 537)	θ value	0.00175202 (rank : 247)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

MT1L_HUMAN
NC score	0.119240 (rank : 538)	θ value	2.36792 (rank : 618)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	65
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

TNR7_MOUSE
NC score	0.118339 (rank : 539)	θ value	0.279714 (rank : 456)
Query Neighborhood Hits	808	Target Neighborhood Hits	112	Shared Neighborhood Hits	77
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

ADA29_HUMAN
NC score	0.118335 (rank : 540)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	808	Target Neighborhood Hits	247	Shared Neighborhood Hits	144
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

TNR4_HUMAN
NC score	0.117111 (rank : 541)	θ value	θ > 10 (rank : 1113)
Query Neighborhood Hits	808	Target Neighborhood Hits	152	Shared Neighborhood Hits	93
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

SON_HUMAN
NC score	0.116794 (rank : 542)	θ value	2.44474e-05 (rank : 158)
Query Neighborhood Hits	808	Target Neighborhood Hits	1568	Shared Neighborhood Hits	143
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

GP2_HUMAN
NC score	0.116751 (rank : 543)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	808	Target Neighborhood Hits	34	Shared Neighborhood Hits	13
SwissProt Accessions	P55259, Q13338, Q9UIF1	Gene names	GP2
Domain Architecture
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2) (ZAP75).

PODXL_HUMAN
NC score	0.115494 (rank : 544)	θ value	2.36792 (rank : 621)
Query Neighborhood Hits	808	Target Neighborhood Hits	191	Shared Neighborhood Hits	50
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

TNR26_MOUSE
NC score	0.114195 (rank : 545)	θ value	θ > 10 (rank : 1112)
Query Neighborhood Hits	808	Target Neighborhood Hits	106	Shared Neighborhood Hits	82
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

MT1G_HUMAN
NC score	0.113870 (rank : 546)	θ value	0.62314 (rank : 503)
Query Neighborhood Hits	808	Target Neighborhood Hits	63	Shared Neighborhood Hits	55
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

LEUK_HUMAN
NC score	0.113714 (rank : 547)	θ value	1.06291 (rank : 545)
Query Neighborhood Hits	808	Target Neighborhood Hits	213	Shared Neighborhood Hits	43
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

C1R_HUMAN
NC score	0.113680 (rank : 548)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	808	Target Neighborhood Hits	364	Shared Neighborhood Hits	147
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

MT1X_HUMAN
NC score	0.113605 (rank : 549)	θ value	6.88961 (rank : 746)
Query Neighborhood Hits	808	Target Neighborhood Hits	76	Shared Neighborhood Hits	68
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

TNR21_HUMAN
NC score	0.113364 (rank : 550)	θ value	0.21417 (rank : 445)
Query Neighborhood Hits	808	Target Neighborhood Hits	90	Shared Neighborhood Hits	59
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

MDGA1_HUMAN
NC score	0.113141 (rank : 551)	θ value	4.30538e-10 (rank : 69)
Query Neighborhood Hits	808	Target Neighborhood Hits	358	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

TNR5_MOUSE
NC score	0.113102 (rank : 552)	θ value	θ > 10 (rank : 1116)
Query Neighborhood Hits	808	Target Neighborhood Hits	131	Shared Neighborhood Hits	91
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR22_MOUSE
NC score	0.113019 (rank : 553)	θ value	2.36792 (rank : 628)
Query Neighborhood Hits	808	Target Neighborhood Hits	97	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

MEP1B_HUMAN
NC score	0.112683 (rank : 554)	θ value	0.0563607 (rank : 368)
Query Neighborhood Hits	808	Target Neighborhood Hits	98	Shared Neighborhood Hits	72
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

FINC_MOUSE
NC score	0.112085 (rank : 555)	θ value	0.000158464 (rank : 184)
Query Neighborhood Hits	808	Target Neighborhood Hits	309	Shared Neighborhood Hits	88
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

TNR1A_MOUSE
NC score	0.111846 (rank : 556)	θ value	0.21417 (rank : 444)
Query Neighborhood Hits	808	Target Neighborhood Hits	131	Shared Neighborhood Hits	72
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

WISP3_HUMAN
NC score	0.111696 (rank : 557)	θ value	0.279714 (rank : 459)
Query Neighborhood Hits	808	Target Neighborhood Hits	87	Shared Neighborhood Hits	49
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

GP2_MOUSE
NC score	0.111664 (rank : 558)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	808	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D733	Gene names	Gp2
Domain Architecture	No domain graphic available
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2).

APR3_MOUSE
NC score	0.111598 (rank : 559)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	808	Target Neighborhood Hits	61	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

LORI_MOUSE
NC score	0.111049 (rank : 560)	θ value	θ > 10 (rank : 980)
Query Neighborhood Hits	808	Target Neighborhood Hits	47	Shared Neighborhood Hits	22
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

TNR11_HUMAN
NC score	0.111034 (rank : 561)	θ value	θ > 10 (rank : 1105)
Query Neighborhood Hits	808	Target Neighborhood Hits	135	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

KR241_HUMAN
NC score	0.110951 (rank : 562)	θ value	6.88961 (rank : 738)
Query Neighborhood Hits	808	Target Neighborhood Hits	71	Shared Neighborhood Hits	55
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

MASP2_HUMAN
NC score	0.109410 (rank : 563)	θ value	θ > 10 (rank : 993)
Query Neighborhood Hits	808	Target Neighborhood Hits	364	Shared Neighborhood Hits	144
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

APR3_HUMAN
NC score	0.108934 (rank : 564)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	808	Target Neighborhood Hits	50	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

MT1H_HUMAN
NC score	0.108820 (rank : 565)	θ value	θ > 10 (rank : 1002)
Query Neighborhood Hits	808	Target Neighborhood Hits	78	Shared Neighborhood Hits	69
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

IDD_HUMAN
NC score	0.108322 (rank : 566)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	808	Target Neighborhood Hits	127	Shared Neighborhood Hits	57
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

PGH1_HUMAN
NC score	0.108093 (rank : 567)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	808	Target Neighborhood Hits	91	Shared Neighborhood Hits	72
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

MASP2_MOUSE
NC score	0.107980 (rank : 568)	θ value	θ > 10 (rank : 994)
Query Neighborhood Hits	808	Target Neighborhood Hits	382	Shared Neighborhood Hits	150
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

RSPO4_MOUSE
NC score	0.107558 (rank : 569)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	808	Target Neighborhood Hits	110	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

MAVS_HUMAN
NC score	0.107549 (rank : 570)	θ value	0.0252991 (rank : 333)
Query Neighborhood Hits	808	Target Neighborhood Hits	271	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

TMPS6_HUMAN
NC score	0.107508 (rank : 571)	θ value	θ > 10 (rank : 1102)
Query Neighborhood Hits	808	Target Neighborhood Hits	338	Shared Neighborhood Hits	138
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TNR3_MOUSE
NC score	0.107340 (rank : 572)	θ value	1.81305 (rank : 595)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

KR134_HUMAN
NC score	0.107127 (rank : 573)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	808	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

MFRP_HUMAN
NC score	0.106917 (rank : 574)	θ value	θ > 10 (rank : 1000)
Query Neighborhood Hits	808	Target Neighborhood Hits	165	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

TNR11_MOUSE
NC score	0.106791 (rank : 575)	θ value	0.21417 (rank : 443)
Query Neighborhood Hits	808	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

AD26A_MOUSE
NC score	0.106519 (rank : 576)	θ value	4.03905 (rank : 651)
Query Neighborhood Hits	808	Target Neighborhood Hits	165	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

PRG4_MOUSE
NC score	0.105802 (rank : 577)	θ value	0.813845 (rank : 522)
Query Neighborhood Hits	808	Target Neighborhood Hits	624	Shared Neighborhood Hits	109
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SPR2F_HUMAN
NC score	0.105366 (rank : 578)	θ value	1.06291 (rank : 555)
Query Neighborhood Hits	808	Target Neighborhood Hits	33	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

CSMD1_MOUSE
NC score	0.105159 (rank : 579)	θ value	1.87187e-05 (rank : 154)
Query Neighborhood Hits	808	Target Neighborhood Hits	193	Shared Neighborhood Hits	78
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

TNR3_HUMAN
NC score	0.104830 (rank : 580)	θ value	0.62314 (rank : 509)
Query Neighborhood Hits	808	Target Neighborhood Hits	145	Shared Neighborhood Hits	73
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

WFDC2_HUMAN
NC score	0.104728 (rank : 581)	θ value	3.0926 (rank : 650)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	57
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

CSMD1_HUMAN
NC score	0.104357 (rank : 582)	θ value	6.43352e-06 (rank : 139)
Query Neighborhood Hits	808	Target Neighborhood Hits	176	Shared Neighborhood Hits	68
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

HCFC1_HUMAN
NC score	0.104291 (rank : 583)	θ value	0.0148317 (rank : 307)
Query Neighborhood Hits	808	Target Neighborhood Hits	331	Shared Neighborhood Hits	74
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MAMC1_MOUSE
NC score	0.104256 (rank : 584)	θ value	3.08544e-08 (rank : 89)
Query Neighborhood Hits	808	Target Neighborhood Hits	357	Shared Neighborhood Hits	37
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

CS1A_MOUSE
NC score	0.103401 (rank : 585)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	808	Target Neighborhood Hits	360	Shared Neighborhood Hits	143
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

TPA_MOUSE
NC score	0.103310 (rank : 586)	θ value	4.03905 (rank : 679)
Query Neighborhood Hits	808	Target Neighborhood Hits	335	Shared Neighborhood Hits	145
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

CS1B_MOUSE
NC score	0.103192 (rank : 587)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	808	Target Neighborhood Hits	361	Shared Neighborhood Hits	141
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

NRG2_HUMAN
NC score	0.103116 (rank : 588)	θ value	θ > 10 (rank : 1022)
Query Neighborhood Hits	808	Target Neighborhood Hits	419	Shared Neighborhood Hits	113
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

MAMC1_HUMAN
NC score	0.103083 (rank : 589)	θ value	4.0297e-08 (rank : 93)
Query Neighborhood Hits	808	Target Neighborhood Hits	357	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

TNR1A_HUMAN
NC score	0.103011 (rank : 590)	θ value	2.36792 (rank : 627)
Query Neighborhood Hits	808	Target Neighborhood Hits	121	Shared Neighborhood Hits	65
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

MUC1_HUMAN
NC score	0.102989 (rank : 591)	θ value	1.058e-16 (rank : 33)
Query Neighborhood Hits	808	Target Neighborhood Hits	975	Shared Neighborhood Hits	87
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

TMPS6_MOUSE
NC score	0.102737 (rank : 592)	θ value	θ > 10 (rank : 1103)
Query Neighborhood Hits	808	Target Neighborhood Hits	341	Shared Neighborhood Hits	140
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

BAI1_HUMAN
NC score	0.102299 (rank : 593)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	808	Target Neighborhood Hits	375	Shared Neighborhood Hits	102
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

MASP1_HUMAN
NC score	0.101606 (rank : 594)	θ value	θ > 10 (rank : 991)
Query Neighborhood Hits	808	Target Neighborhood Hits	369	Shared Neighborhood Hits	143
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

HCFC1_MOUSE
NC score	0.101412 (rank : 595)	θ value	0.00869519 (rank : 294)
Query Neighborhood Hits	808	Target Neighborhood Hits	348	Shared Neighborhood Hits	72
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

ADA20_HUMAN
NC score	0.101263 (rank : 596)	θ value	0.813845 (rank : 510)
Query Neighborhood Hits	808	Target Neighborhood Hits	143	Shared Neighborhood Hits	106
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

C1S_HUMAN
NC score	0.100580 (rank : 597)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	808	Target Neighborhood Hits	359	Shared Neighborhood Hits	145
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

BAI3_MOUSE
NC score	0.099903 (rank : 598)	θ value	0.365318 (rank : 463)
Query Neighborhood Hits	808	Target Neighborhood Hits	250	Shared Neighborhood Hits	86
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

TPA_HUMAN
NC score	0.099875 (rank : 599)	θ value	θ > 10 (rank : 1119)
Query Neighborhood Hits	808	Target Neighborhood Hits	324	Shared Neighborhood Hits	142
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

FINC_HUMAN
NC score	0.099615 (rank : 600)	θ value	0.0736092 (rank : 379)
Query Neighborhood Hits	808	Target Neighborhood Hits	302	Shared Neighborhood Hits	82
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

TR11B_MOUSE
NC score	0.099429 (rank : 601)	θ value	0.0431538 (rank : 363)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

MASP1_MOUSE
NC score	0.098846 (rank : 602)	θ value	θ > 10 (rank : 992)
Query Neighborhood Hits	808	Target Neighborhood Hits	364	Shared Neighborhood Hits	141
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

IDD_MOUSE
NC score	0.098511 (rank : 603)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	808	Target Neighborhood Hits	151	Shared Neighborhood Hits	59
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

MAGE1_HUMAN
NC score	0.098357 (rank : 604)	θ value	9.92553e-07 (rank : 121)
Query Neighborhood Hits	808	Target Neighborhood Hits	1389	Shared Neighborhood Hits	129
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

BAI1_MOUSE
NC score	0.098308 (rank : 605)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	808	Target Neighborhood Hits	340	Shared Neighborhood Hits	97
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

KR132_HUMAN
NC score	0.097857 (rank : 606)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	808	Target Neighborhood Hits	69	Shared Neighborhood Hits	55
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

RSPO2_MOUSE
NC score	0.097699 (rank : 607)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	808	Target Neighborhood Hits	88	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO2_HUMAN
NC score	0.097129 (rank : 608)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	808	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

PROP_MOUSE
NC score	0.097061 (rank : 609)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	808	Target Neighborhood Hits	165	Shared Neighborhood Hits	70
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

BAI3_HUMAN
NC score	0.096923 (rank : 610)	θ value	0.21417 (rank : 427)
Query Neighborhood Hits	808	Target Neighborhood Hits	246	Shared Neighborhood Hits	82
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CSMD3_HUMAN
NC score	0.096736 (rank : 611)	θ value	0.0252991 (rank : 328)
Query Neighborhood Hits	808	Target Neighborhood Hits	199	Shared Neighborhood Hits	73
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

ENTK_MOUSE
NC score	0.096720 (rank : 612)	θ value	0.00228821 (rank : 253)
Query Neighborhood Hits	808	Target Neighborhood Hits	338	Shared Neighborhood Hits	93
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TR11B_HUMAN
NC score	0.096372 (rank : 613)	θ value	0.0252991 (rank : 336)
Query Neighborhood Hits	808	Target Neighborhood Hits	92	Shared Neighborhood Hits	57
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

KR121_HUMAN
NC score	0.095813 (rank : 614)	θ value	1.38821 (rank : 566)
Query Neighborhood Hits	808	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	P59990	Gene names	KRTAP12-1, KAP12.1, KRTAP12.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-1 (Keratin-associated protein 12.1) (High sulfur keratin-associated protein 12.1).

CUZD1_HUMAN
NC score	0.095691 (rank : 615)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	808	Target Neighborhood Hits	89	Shared Neighborhood Hits	29
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

RSPO1_HUMAN
NC score	0.095397 (rank : 616)	θ value	5.27518 (rank : 703)
Query Neighborhood Hits	808	Target Neighborhood Hits	101	Shared Neighborhood Hits	66
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

TNR6_MOUSE
NC score	0.095048 (rank : 617)	θ value	θ > 10 (rank : 1118)
Query Neighborhood Hits	808	Target Neighborhood Hits	99	Shared Neighborhood Hits	70
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

KR133_HUMAN
NC score	0.095046 (rank : 618)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	808	Target Neighborhood Hits	66	Shared Neighborhood Hits	58
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

MT1F_HUMAN
NC score	0.095011 (rank : 619)	θ value	2.36792 (rank : 617)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	65
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

TSG6_MOUSE
NC score	0.094899 (rank : 620)	θ value	θ > 10 (rank : 1125)
Query Neighborhood Hits	808	Target Neighborhood Hits	91	Shared Neighborhood Hits	36
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

ATS9_HUMAN
NC score	0.094891 (rank : 621)	θ value	0.000461057 (rank : 207)
Query Neighborhood Hits	808	Target Neighborhood Hits	219	Shared Neighborhood Hits	130
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

TM108_MOUSE
NC score	0.094378 (rank : 622)	θ value	0.21417 (rank : 441)
Query Neighborhood Hits	808	Target Neighborhood Hits	336	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TSG6_HUMAN
NC score	0.094111 (rank : 623)	θ value	θ > 10 (rank : 1124)
Query Neighborhood Hits	808	Target Neighborhood Hits	91	Shared Neighborhood Hits	37
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TNR1B_HUMAN
NC score	0.093921 (rank : 624)	θ value	θ > 10 (rank : 1110)
Query Neighborhood Hits	808	Target Neighborhood Hits	127	Shared Neighborhood Hits	78
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1B_MOUSE
NC score	0.093636 (rank : 625)	θ value	1.06291 (rank : 556)
Query Neighborhood Hits	808	Target Neighborhood Hits	123	Shared Neighborhood Hits	68
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

MSMB_HUMAN
NC score	0.093501 (rank : 626)	θ value	0.0193708 (rank : 317)
Query Neighborhood Hits	808	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	P08118, P11999, Q13125, Q9UC59	Gene names	MSMB, PRSP
Domain Architecture
Description	Beta-microseminoprotein precursor (Prostate secreted seminal plasma protein) (Prostate secretory protein PSP94) (PSP-94) (Seminal plasma beta-inhibin) (Immunoglobulin-binding factor) (IGBF) (PN44).

VASN_HUMAN
NC score	0.093236 (rank : 627)	θ value	θ > 10 (rank : 1131)
Query Neighborhood Hits	808	Target Neighborhood Hits	449	Shared Neighborhood Hits	138
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

CUZD1_MOUSE
NC score	0.093071 (rank : 628)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	808	Target Neighborhood Hits	91	Shared Neighborhood Hits	31
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

CN037_HUMAN
NC score	0.092709 (rank : 629)	θ value	0.00228821 (rank : 252)
Query Neighborhood Hits	808	Target Neighborhood Hits	118	Shared Neighborhood Hits	24
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

MFRP_MOUSE
NC score	0.091905 (rank : 630)	θ value	θ > 10 (rank : 1001)
Query Neighborhood Hits	808	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CN155_HUMAN
NC score	0.091281 (rank : 631)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	808	Target Neighborhood Hits	385	Shared Neighborhood Hits	66
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

MT1E_HUMAN
NC score	0.091112 (rank : 632)	θ value	5.27518 (rank : 700)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

CSMD2_HUMAN
NC score	0.090902 (rank : 633)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	808	Target Neighborhood Hits	188	Shared Neighborhood Hits	68
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

BAI2_MOUSE
NC score	0.090421 (rank : 634)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	808	Target Neighborhood Hits	323	Shared Neighborhood Hits	83
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

ENTK_HUMAN
NC score	0.090146 (rank : 635)	θ value	0.000158464 (rank : 183)
Query Neighborhood Hits	808	Target Neighborhood Hits	310	Shared Neighborhood Hits	85
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TXND2_HUMAN
NC score	0.090016 (rank : 636)	θ value	6.87365e-08 (rank : 100)
Query Neighborhood Hits	808	Target Neighborhood Hits	793	Shared Neighborhood Hits	68
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TR10C_HUMAN
NC score	0.089927 (rank : 637)	θ value	0.0563607 (rank : 371)
Query Neighborhood Hits	808	Target Neighborhood Hits	105	Shared Neighborhood Hits	59
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

ALMS1_HUMAN
NC score	0.089695 (rank : 638)	θ value	0.000602161 (rank : 212)
Query Neighborhood Hits	808	Target Neighborhood Hits	356	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

SDC3_HUMAN
NC score	0.089079 (rank : 639)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	808	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

BAI2_HUMAN
NC score	0.088527 (rank : 640)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	808	Target Neighborhood Hits	332	Shared Neighborhood Hits	79
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TNR5_HUMAN
NC score	0.087932 (rank : 641)	θ value	θ > 10 (rank : 1115)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	73
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

EREG_HUMAN
NC score	0.087906 (rank : 642)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	52
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

VASN_MOUSE
NC score	0.087368 (rank : 643)	θ value	5.27518 (rank : 713)
Query Neighborhood Hits	808	Target Neighborhood Hits	426	Shared Neighborhood Hits	126
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

DKK3_MOUSE
NC score	0.086991 (rank : 644)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	808	Target Neighborhood Hits	83	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

TAU_MOUSE
NC score	0.085781 (rank : 645)	θ value	1.38821 (rank : 577)
Query Neighborhood Hits	808	Target Neighborhood Hits	502	Shared Neighborhood Hits	55
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

PME17_HUMAN
NC score	0.085578 (rank : 646)	θ value	0.0113563 (rank : 303)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	30
SwissProt Accessions	P40967, Q12763, Q14448, Q14817, Q16565	Gene names	SILV, D12S53E, PMEL17
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Melanocyte lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (ME20M/ME20S) (ME20- M/ME20-S) (95 kDa melanocyte-specific secreted glycoprotein).

CO002_HUMAN
NC score	0.085136 (rank : 647)	θ value	5.27518 (rank : 686)
Query Neighborhood Hits	808	Target Neighborhood Hits	387	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

PTPRK_MOUSE
NC score	0.085108 (rank : 648)	θ value	2.61198e-07 (rank : 109)
Query Neighborhood Hits	808	Target Neighborhood Hits	223	Shared Neighborhood Hits	57
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

SPIT1_MOUSE
NC score	0.084788 (rank : 649)	θ value	1.06291 (rank : 553)
Query Neighborhood Hits	808	Target Neighborhood Hits	96	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

PTPRK_HUMAN
NC score	0.084717 (rank : 650)	θ value	1.99992e-07 (rank : 107)
Query Neighborhood Hits	808	Target Neighborhood Hits	228	Shared Neighborhood Hits	58
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PROP_HUMAN
NC score	0.084122 (rank : 651)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	808	Target Neighborhood Hits	126	Shared Neighborhood Hits	52
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

TMPS7_MOUSE
NC score	0.083281 (rank : 652)	θ value	0.21417 (rank : 442)
Query Neighborhood Hits	808	Target Neighborhood Hits	275	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

SPRR3_MOUSE
NC score	0.082942 (rank : 653)	θ value	0.47712 (rank : 490)
Query Neighborhood Hits	808	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

PTPRU_HUMAN
NC score	0.082898 (rank : 654)	θ value	4.1701e-05 (rank : 165)
Query Neighborhood Hits	808	Target Neighborhood Hits	237	Shared Neighborhood Hits	58
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

RTP3_MOUSE
NC score	0.082690 (rank : 655)	θ value	0.0736092 (rank : 384)
Query Neighborhood Hits	808	Target Neighborhood Hits	374	Shared Neighborhood Hits	52
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

FSTL1_HUMAN
NC score	0.082409 (rank : 656)	θ value	8.99809 (rank : 776)
Query Neighborhood Hits	808	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

TNR6_HUMAN
NC score	0.082044 (rank : 657)	θ value	θ > 10 (rank : 1117)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	63
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

GSCR1_HUMAN
NC score	0.081632 (rank : 658)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	808	Target Neighborhood Hits	674	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

LRP11_MOUSE
NC score	0.081632 (rank : 659)	θ value	θ > 10 (rank : 986)
Query Neighborhood Hits	808	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

GLU2B_HUMAN
NC score	0.081410 (rank : 660)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	808	Target Neighborhood Hits	377	Shared Neighborhood Hits	59
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

COCA1_MOUSE
NC score	0.081309 (rank : 661)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	808	Target Neighborhood Hits	467	Shared Neighborhood Hits	72
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

ODFP_MOUSE
NC score	0.080927 (rank : 662)	θ value	0.279714 (rank : 453)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

SPIT1_HUMAN
NC score	0.080820 (rank : 663)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	808	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

NU214_HUMAN
NC score	0.080623 (rank : 664)	θ value	θ > 10 (rank : 1031)
Query Neighborhood Hits	808	Target Neighborhood Hits	657	Shared Neighborhood Hits	78
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

EMSY_HUMAN
NC score	0.080250 (rank : 665)	θ value	0.0563607 (rank : 365)
Query Neighborhood Hits	808	Target Neighborhood Hits	296	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

PAP2_HUMAN
NC score	0.080228 (rank : 666)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	808	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

ATS20_MOUSE
NC score	0.080184 (rank : 667)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	808	Target Neighborhood Hits	225	Shared Neighborhood Hits	122
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

TR10A_HUMAN
NC score	0.079968 (rank : 668)	θ value	0.163984 (rank : 425)
Query Neighborhood Hits	808	Target Neighborhood Hits	82	Shared Neighborhood Hits	50
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

SPR2E_HUMAN
NC score	0.079841 (rank : 669)	θ value	3.0926 (rank : 645)
Query Neighborhood Hits	808	Target Neighborhood Hits	32	Shared Neighborhood Hits	20
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

MT2_HUMAN
NC score	0.079561 (rank : 670)	θ value	6.88961 (rank : 747)
Query Neighborhood Hits	808	Target Neighborhood Hits	69	Shared Neighborhood Hits	62
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

TMPS7_HUMAN
NC score	0.079377 (rank : 671)	θ value	θ > 10 (rank : 1104)
Query Neighborhood Hits	808	Target Neighborhood Hits	275	Shared Neighborhood Hits	85
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

EMSY_MOUSE
NC score	0.079036 (rank : 672)	θ value	0.0431538 (rank : 353)
Query Neighborhood Hits	808	Target Neighborhood Hits	294	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

FSTL1_MOUSE
NC score	0.079009 (rank : 673)	θ value	6.88961 (rank : 731)
Query Neighborhood Hits	808	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

PGCA_MOUSE
NC score	0.078849 (rank : 674)	θ value	3.0926 (rank : 643)
Query Neighborhood Hits	808	Target Neighborhood Hits	643	Shared Neighborhood Hits	71
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

MUCEN_MOUSE
NC score	0.078619 (rank : 675)	θ value	1.06291 (rank : 551)
Query Neighborhood Hits	808	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

MLL3_MOUSE
NC score	0.078525 (rank : 676)	θ value	0.00509761 (rank : 277)
Query Neighborhood Hits	808	Target Neighborhood Hits	1399	Shared Neighborhood Hits	157
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NETO2_HUMAN
NC score	0.078324 (rank : 677)	θ value	θ > 10 (rank : 1016)
Query Neighborhood Hits	808	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

COKA1_HUMAN
NC score	0.078197 (rank : 678)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	808	Target Neighborhood Hits	403	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

NETO2_MOUSE
NC score	0.078044 (rank : 679)	θ value	θ > 10 (rank : 1017)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

TECTB_MOUSE
NC score	0.077913 (rank : 680)	θ value	θ > 10 (rank : 1097)
Query Neighborhood Hits	808	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	O08524	Gene names	Tectb
Domain Architecture
Description	Beta-tectorin precursor.

ZN207_HUMAN
NC score	0.077794 (rank : 681)	θ value	θ > 10 (rank : 1135)
Query Neighborhood Hits	808	Target Neighborhood Hits	326	Shared Neighborhood Hits	47
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

COCA1_HUMAN
NC score	0.077728 (rank : 682)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	808	Target Neighborhood Hits	458	Shared Neighborhood Hits	70
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

ATS20_HUMAN
NC score	0.077234 (rank : 683)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	808	Target Neighborhood Hits	192	Shared Neighborhood Hits	107
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

DKK3_HUMAN
NC score	0.077085 (rank : 684)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	808	Target Neighborhood Hits	74	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

TR10D_HUMAN
NC score	0.077001 (rank : 685)	θ value	0.00509761 (rank : 280)
Query Neighborhood Hits	808	Target Neighborhood Hits	62	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

LRP11_HUMAN
NC score	0.076965 (rank : 686)	θ value	θ > 10 (rank : 985)
Query Neighborhood Hits	808	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

SEZ6L_HUMAN
NC score	0.076918 (rank : 687)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	808	Target Neighborhood Hits	289	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

PRP2_MOUSE
NC score	0.076856 (rank : 688)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	808	Target Neighborhood Hits	347	Shared Neighborhood Hits	43
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

MLL3_HUMAN
NC score	0.076402 (rank : 689)	θ value	3.0926 (rank : 641)
Query Neighborhood Hits	808	Target Neighborhood Hits	1644	Shared Neighborhood Hits	163
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

LAD1_MOUSE
NC score	0.076338 (rank : 690)	θ value	0.000461057 (rank : 211)
Query Neighborhood Hits	808	Target Neighborhood Hits	391	Shared Neighborhood Hits	49
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

NRG3_MOUSE
NC score	0.076296 (rank : 691)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	808	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

SDC3_MOUSE
NC score	0.076195 (rank : 692)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	808	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

PO121_HUMAN
NC score	0.076166 (rank : 693)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	808	Target Neighborhood Hits	344	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

NETO1_MOUSE
NC score	0.076099 (rank : 694)	θ value	θ > 10 (rank : 1015)
Query Neighborhood Hits	808	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_HUMAN
NC score	0.075895 (rank : 695)	θ value	θ > 10 (rank : 1014)
Query Neighborhood Hits	808	Target Neighborhood Hits	110	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

GP126_HUMAN
NC score	0.075862 (rank : 696)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	808	Target Neighborhood Hits	187	Shared Neighborhood Hits	44
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

RSPO1_MOUSE
NC score	0.075642 (rank : 697)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	808	Target Neighborhood Hits	85	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

CFAI_HUMAN
NC score	0.075621 (rank : 698)	θ value	1.06291 (rank : 534)
Query Neighborhood Hits	808	Target Neighborhood Hits	289	Shared Neighborhood Hits	75
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

TECTB_HUMAN
NC score	0.075504 (rank : 699)	θ value	θ > 10 (rank : 1096)
Query Neighborhood Hits	808	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PL2	Gene names	TECTB
Domain Architecture
Description	Beta-tectorin precursor.

MT1M_HUMAN
NC score	0.075146 (rank : 700)	θ value	6.88961 (rank : 745)
Query Neighborhood Hits	808	Target Neighborhood Hits	72	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

MLL2_HUMAN
NC score	0.074990 (rank : 701)	θ value	8.99809 (rank : 785)
Query Neighborhood Hits	808	Target Neighborhood Hits	1788	Shared Neighborhood Hits	169
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CFAI_MOUSE
NC score	0.074907 (rank : 702)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	808	Target Neighborhood Hits	290	Shared Neighborhood Hits	79
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

SHBG_HUMAN
NC score	0.074054 (rank : 703)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	808	Target Neighborhood Hits	45	Shared Neighborhood Hits	34
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SPON1_MOUSE
NC score	0.073909 (rank : 704)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	808	Target Neighborhood Hits	123	Shared Neighborhood Hits	58
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

CSPG4_MOUSE
NC score	0.073449 (rank : 705)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	808	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

TRI42_MOUSE
NC score	0.072857 (rank : 706)	θ value	2.36792 (rank : 629)
Query Neighborhood Hits	808	Target Neighborhood Hits	316	Shared Neighborhood Hits	83
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

NCOA6_MOUSE
NC score	0.072650 (rank : 707)	θ value	θ > 10 (rank : 1011)
Query Neighborhood Hits	808	Target Neighborhood Hits	1076	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PTPRT_MOUSE
NC score	0.072577 (rank : 708)	θ value	0.0431538 (rank : 361)
Query Neighborhood Hits	808	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

CSPG4_HUMAN
NC score	0.072475 (rank : 709)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	808	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

ATS12_HUMAN
NC score	0.072448 (rank : 710)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	808	Target Neighborhood Hits	251	Shared Neighborhood Hits	116
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

PTPRT_HUMAN
NC score	0.072368 (rank : 711)	θ value	0.0431538 (rank : 360)
Query Neighborhood Hits	808	Target Neighborhood Hits	217	Shared Neighborhood Hits	56
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

COEA1_MOUSE
NC score	0.072338 (rank : 712)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	808	Target Neighborhood Hits	402	Shared Neighborhood Hits	62
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

CO1A1_MOUSE
NC score	0.072274 (rank : 713)	θ value	0.279714 (rank : 450)
Query Neighborhood Hits	808	Target Neighborhood Hits	457	Shared Neighborhood Hits	86
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

ATS16_HUMAN
NC score	0.071950 (rank : 714)	θ value	0.365318 (rank : 461)
Query Neighborhood Hits	808	Target Neighborhood Hits	208	Shared Neighborhood Hits	114
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

MCSP_HUMAN
NC score	0.071806 (rank : 715)	θ value	θ > 10 (rank : 998)
Query Neighborhood Hits	808	Target Neighborhood Hits	48	Shared Neighborhood Hits	31
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

TNR19_HUMAN
NC score	0.071797 (rank : 716)	θ value	θ > 10 (rank : 1108)
Query Neighborhood Hits	808	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

PTPRM_HUMAN
NC score	0.071589 (rank : 717)	θ value	0.0431538 (rank : 359)
Query Neighborhood Hits	808	Target Neighborhood Hits	244	Shared Neighborhood Hits	57
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

DMBT1_MOUSE
NC score	0.071583 (rank : 718)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	808	Target Neighborhood Hits	134	Shared Neighborhood Hits	34
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

SPON1_HUMAN
NC score	0.071562 (rank : 719)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	808	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

K1683_HUMAN
NC score	0.071496 (rank : 720)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	808	Target Neighborhood Hits	240	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

MT1I_HUMAN
NC score	0.071303 (rank : 721)	θ value	6.88961 (rank : 744)
Query Neighborhood Hits	808	Target Neighborhood Hits	64	Shared Neighborhood Hits	57
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

RTN4_MOUSE
NC score	0.071267 (rank : 722)	θ value	0.000602161 (rank : 216)
Query Neighborhood Hits	808	Target Neighborhood Hits	341	Shared Neighborhood Hits	44
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

COEA1_HUMAN
NC score	0.071248 (rank : 723)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	808	Target Neighborhood Hits	427	Shared Neighborhood Hits	61
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

GNPTA_HUMAN
NC score	0.071206 (rank : 724)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	808	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

SRRM1_MOUSE
NC score	0.071204 (rank : 725)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	808	Target Neighborhood Hits	966	Shared Neighborhood Hits	83
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ATS7_HUMAN
NC score	0.070686 (rank : 726)	θ value	8.99809 (rank : 766)
Query Neighborhood Hits	808	Target Neighborhood Hits	169	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

GLU2B_MOUSE
NC score	0.070642 (rank : 727)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	808	Target Neighborhood Hits	357	Shared Neighborhood Hits	49
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

PTPRM_MOUSE
NC score	0.070629 (rank : 728)	θ value	0.163984 (rank : 421)
Query Neighborhood Hits	808	Target Neighborhood Hits	238	Shared Neighborhood Hits	55
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

ATS18_HUMAN
NC score	0.070292 (rank : 729)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	808	Target Neighborhood Hits	169	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

TR10B_MOUSE
NC score	0.070007 (rank : 730)	θ value	θ > 10 (rank : 1121)
Query Neighborhood Hits	808	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

EPGN_MOUSE
NC score	0.070001 (rank : 731)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	808	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

GNPTA_MOUSE
NC score	0.069913 (rank : 732)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	808	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

PARM1_MOUSE
NC score	0.069767 (rank : 733)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	808	Target Neighborhood Hits	140	Shared Neighborhood Hits	35
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

SHBG_MOUSE
NC score	0.069586 (rank : 734)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	808	Target Neighborhood Hits	50	Shared Neighborhood Hits	39
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

AMPH_HUMAN
NC score	0.069517 (rank : 735)	θ value	1.43324e-05 (rank : 148)
Query Neighborhood Hits	808	Target Neighborhood Hits	455	Shared Neighborhood Hits	43
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

PCLO_HUMAN
NC score	0.069497 (rank : 736)	θ value	0.125558 (rank : 405)
Query Neighborhood Hits	808	Target Neighborhood Hits	2046	Shared Neighborhood Hits	142
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CR001_HUMAN
NC score	0.069270 (rank : 737)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	808	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

TINAG_HUMAN
NC score	0.069237 (rank : 738)	θ value	3.0926 (rank : 648)
Query Neighborhood Hits	808	Target Neighborhood Hits	63	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

TNR18_HUMAN
NC score	0.069221 (rank : 739)	θ value	θ > 10 (rank : 1107)
Query Neighborhood Hits	808	Target Neighborhood Hits	55	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

NRG3_HUMAN
NC score	0.068925 (rank : 740)	θ value	θ > 10 (rank : 1024)
Query Neighborhood Hits	808	Target Neighborhood Hits	119	Shared Neighborhood Hits	67
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

DCBD1_HUMAN
NC score	0.068846 (rank : 741)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	808	Target Neighborhood Hits	110	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

CO7A1_HUMAN
NC score	0.068376 (rank : 742)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	808	Target Neighborhood Hits	807	Shared Neighborhood Hits	96
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

ATS16_MOUSE
NC score	0.068230 (rank : 743)	θ value	5.27518 (rank : 683)
Query Neighborhood Hits	808	Target Neighborhood Hits	179	Shared Neighborhood Hits	99
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

GP128_MOUSE
NC score	0.068076 (rank : 744)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	808	Target Neighborhood Hits	141	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

CR001_MOUSE
NC score	0.067841 (rank : 745)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	808	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

ATS12_MOUSE
NC score	0.067198 (rank : 746)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	808	Target Neighborhood Hits	220	Shared Neighborhood Hits	110
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

KRA32_HUMAN
NC score	0.067189 (rank : 747)	θ value	θ > 10 (rank : 975)
Query Neighborhood Hits	808	Target Neighborhood Hits	51	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYR7	Gene names	KRTAP3-2, KAP3.2, KRTAP3.2
Domain Architecture
Description	Keratin-associated protein 3-2 (Keratin-associated protein 3.2) (High sulfur keratin-associated protein 3.2).

SELPL_HUMAN
NC score	0.066981 (rank : 748)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	808	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q14242, Q12775	Gene names	SELPLG
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand) (CD162 antigen).

TNR19_MOUSE
NC score	0.066884 (rank : 749)	θ value	θ > 10 (rank : 1109)
Query Neighborhood Hits	808	Target Neighborhood Hits	100	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

CN037_MOUSE
NC score	0.066779 (rank : 750)	θ value	2.36792 (rank : 607)
Query Neighborhood Hits	808	Target Neighborhood Hits	179	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

DMBT1_HUMAN
NC score	0.066672 (rank : 751)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	808	Target Neighborhood Hits	152	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

ADEC1_MOUSE
NC score	0.066579 (rank : 752)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	808	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

CP003_HUMAN
NC score	0.066535 (rank : 753)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	808	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

ATS1_MOUSE
NC score	0.066348 (rank : 754)	θ value	0.365318 (rank : 462)
Query Neighborhood Hits	808	Target Neighborhood Hits	158	Shared Neighborhood Hits	89
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

TR10B_HUMAN
NC score	0.066207 (rank : 755)	θ value	θ > 10 (rank : 1120)
Query Neighborhood Hits	808	Target Neighborhood Hits	71	Shared Neighborhood Hits	46
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

CO1A1_HUMAN
NC score	0.066181 (rank : 756)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	808	Target Neighborhood Hits	475	Shared Neighborhood Hits	86
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

BTC_HUMAN
NC score	0.066173 (rank : 757)	θ value	5.27518 (rank : 684)
Query Neighborhood Hits	808	Target Neighborhood Hits	70	Shared Neighborhood Hits	46
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

LEUK_MOUSE
NC score	0.066146 (rank : 758)	θ value	θ > 10 (rank : 979)
Query Neighborhood Hits	808	Target Neighborhood Hits	147	Shared Neighborhood Hits	31
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

ATS17_HUMAN
NC score	0.066021 (rank : 759)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	808	Target Neighborhood Hits	194	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS13_MOUSE
NC score	0.065924 (rank : 760)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	808	Target Neighborhood Hits	227	Shared Neighborhood Hits	108
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

LAD1_HUMAN
NC score	0.065709 (rank : 761)	θ value	θ > 10 (rank : 977)
Query Neighborhood Hits	808	Target Neighborhood Hits	441	Shared Neighborhood Hits	42
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

PODXL_MOUSE
NC score	0.065560 (rank : 762)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	808	Target Neighborhood Hits	130	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R0M4, Q9ESZ1	Gene names	Podxl, Pclp1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

NEU1_MOUSE
NC score	0.065427 (rank : 763)	θ value	θ > 10 (rank : 1018)
Query Neighborhood Hits	808	Target Neighborhood Hits	64	Shared Neighborhood Hits	53
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

SEM5A_HUMAN
NC score	0.065394 (rank : 764)	θ value	0.125558 (rank : 406)
Query Neighborhood Hits	808	Target Neighborhood Hits	177	Shared Neighborhood Hits	69
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ATS14_HUMAN
NC score	0.065328 (rank : 765)	θ value	8.99809 (rank : 764)
Query Neighborhood Hits	808	Target Neighborhood Hits	382	Shared Neighborhood Hits	106
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

KI67_HUMAN
NC score	0.065143 (rank : 766)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	808	Target Neighborhood Hits	581	Shared Neighborhood Hits	47
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MBD6_HUMAN
NC score	0.065101 (rank : 767)	θ value	θ > 10 (rank : 997)
Query Neighborhood Hits	808	Target Neighborhood Hits	349	Shared Neighborhood Hits	53
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

ADEC1_HUMAN
NC score	0.064931 (rank : 768)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	808	Target Neighborhood Hits	80	Shared Neighborhood Hits	48
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

DCBD2_MOUSE
NC score	0.064925 (rank : 769)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

ATS13_HUMAN
NC score	0.064877 (rank : 770)	θ value	0.0961366 (rank : 385)
Query Neighborhood Hits	808	Target Neighborhood Hits	238	Shared Neighborhood Hits	82
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

TCOF_MOUSE
NC score	0.064747 (rank : 771)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	808	Target Neighborhood Hits	471	Shared Neighborhood Hits	52
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

ZP4_HUMAN
NC score	0.064566 (rank : 772)	θ value	θ > 10 (rank : 1138)
Query Neighborhood Hits	808	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

DCBD2_HUMAN
NC score	0.064400 (rank : 773)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	808	Target Neighborhood Hits	118	Shared Neighborhood Hits	39
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

SHAN1_HUMAN
NC score	0.064356 (rank : 774)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	808	Target Neighborhood Hits	1041	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PCOC1_MOUSE
NC score	0.064342 (rank : 775)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	808	Target Neighborhood Hits	100	Shared Neighborhood Hits	33
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

ATS18_MOUSE
NC score	0.064014 (rank : 776)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	808	Target Neighborhood Hits	163	Shared Neighborhood Hits	88
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

MUCDL_HUMAN
NC score	0.063943 (rank : 777)	θ value	θ > 10 (rank : 1008)
Query Neighborhood Hits	808	Target Neighborhood Hits	777	Shared Neighborhood Hits	78
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

FURIN_MOUSE
NC score	0.063901 (rank : 778)	θ value	0.47712 (rank : 483)
Query Neighborhood Hits	808	Target Neighborhood Hits	49	Shared Neighborhood Hits	26
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

TAU_HUMAN
NC score	0.063871 (rank : 779)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	808	Target Neighborhood Hits	448	Shared Neighborhood Hits	56
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

GP128_HUMAN
NC score	0.063809 (rank : 780)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	808	Target Neighborhood Hits	135	Shared Neighborhood Hits	49
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

IMPG1_HUMAN
NC score	0.063725 (rank : 781)	θ value	1.06291 (rank : 540)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	29
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

CO5A2_HUMAN
NC score	0.063699 (rank : 782)	θ value	0.365318 (rank : 464)
Query Neighborhood Hits	808	Target Neighborhood Hits	760	Shared Neighborhood Hits	101
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

LR37B_HUMAN
NC score	0.063567 (rank : 783)	θ value	1.06291 (rank : 546)
Query Neighborhood Hits	808	Target Neighborhood Hits	392	Shared Neighborhood Hits	55
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

SEM5B_MOUSE
NC score	0.063438 (rank : 784)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	808	Target Neighborhood Hits	190	Shared Neighborhood Hits	74
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

TM108_HUMAN
NC score	0.063359 (rank : 785)	θ value	θ > 10 (rank : 1101)
Query Neighborhood Hits	808	Target Neighborhood Hits	166	Shared Neighborhood Hits	35
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TAF4_HUMAN
NC score	0.063340 (rank : 786)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	808	Target Neighborhood Hits	687	Shared Neighborhood Hits	62
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

SRRM2_MOUSE
NC score	0.063337 (rank : 787)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	808	Target Neighborhood Hits	1470	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MAP1B_HUMAN
NC score	0.063271 (rank : 788)	θ value	0.00175202 (rank : 245)
Query Neighborhood Hits	808	Target Neighborhood Hits	903	Shared Neighborhood Hits	69
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

DAF1_MOUSE
NC score	0.063242 (rank : 789)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	808	Target Neighborhood Hits	204	Shared Neighborhood Hits	47
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

FA47B_HUMAN
NC score	0.063232 (rank : 790)	θ value	0.0252991 (rank : 329)
Query Neighborhood Hits	808	Target Neighborhood Hits	431	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

ANK2_HUMAN
NC score	0.063220 (rank : 791)	θ value	5.27518 (rank : 682)
Query Neighborhood Hits	808	Target Neighborhood Hits	1615	Shared Neighborhood Hits	119
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

PRR12_HUMAN
NC score	0.063208 (rank : 792)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	808	Target Neighborhood Hits	460	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

ATS1_HUMAN
NC score	0.063116 (rank : 793)	θ value	1.81305 (rank : 583)
Query Neighborhood Hits	808	Target Neighborhood Hits	159	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

PO121_MOUSE
NC score	0.063026 (rank : 794)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	808	Target Neighborhood Hits	345	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

RAPH1_HUMAN
NC score	0.063003 (rank : 795)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	808	Target Neighborhood Hits	593	Shared Neighborhood Hits	70
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

BSN_MOUSE
NC score	0.062528 (rank : 796)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	808	Target Neighborhood Hits	2057	Shared Neighborhood Hits	136
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ARID2_HUMAN
NC score	0.062479 (rank : 797)	θ value	0.0736092 (rank : 374)
Query Neighborhood Hits	808	Target Neighborhood Hits	302	Shared Neighborhood Hits	44
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

ATS6_HUMAN
NC score	0.062412 (rank : 798)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	808	Target Neighborhood Hits	141	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

WASIP_MOUSE
NC score	0.062251 (rank : 799)	θ value	θ > 10 (rank : 1134)
Query Neighborhood Hits	808	Target Neighborhood Hits	392	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

BTC_MOUSE
NC score	0.062248 (rank : 800)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	808	Target Neighborhood Hits	67	Shared Neighborhood Hits	45
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

PCOC1_HUMAN
NC score	0.062233 (rank : 801)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	808	Target Neighborhood Hits	146	Shared Neighborhood Hits	30
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

SEM5B_HUMAN
NC score	0.062218 (rank : 802)	θ value	0.365318 (rank : 474)
Query Neighborhood Hits	808	Target Neighborhood Hits	178	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SRPX_MOUSE
NC score	0.062215 (rank : 803)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

ATS8_HUMAN
NC score	0.062083 (rank : 804)	θ value	0.813845 (rank : 513)
Query Neighborhood Hits	808	Target Neighborhood Hits	145	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

PCOC2_MOUSE
NC score	0.062017 (rank : 805)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

HPLN2_MOUSE
NC score	0.061699 (rank : 806)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

SRRM1_HUMAN
NC score	0.061600 (rank : 807)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	808	Target Neighborhood Hits	690	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

HPLN3_MOUSE
NC score	0.061576 (rank : 808)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

TARA_HUMAN
NC score	0.061532 (rank : 809)	θ value	0.62314 (rank : 508)
Query Neighborhood Hits	808	Target Neighborhood Hits	1626	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PCOC2_HUMAN
NC score	0.061531 (rank : 810)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

NFRKB_MOUSE
NC score	0.061409 (rank : 811)	θ value	θ > 10 (rank : 1020)
Query Neighborhood Hits	808	Target Neighborhood Hits	393	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

HPLN2_HUMAN
NC score	0.061328 (rank : 812)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	808	Target Neighborhood Hits	80	Shared Neighborhood Hits	17
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

EPGN_HUMAN
NC score	0.061132 (rank : 813)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	808	Target Neighborhood Hits	59	Shared Neighborhood Hits	40
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

CO3A1_MOUSE
NC score	0.061058 (rank : 814)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	808	Target Neighborhood Hits	466	Shared Neighborhood Hits	66
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

DGKK_HUMAN
NC score	0.061025 (rank : 815)	θ value	0.163984 (rank : 412)
Query Neighborhood Hits	808	Target Neighborhood Hits	378	Shared Neighborhood Hits	60
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

NCOA6_HUMAN
NC score	0.060954 (rank : 816)	θ value	θ > 10 (rank : 1010)
Query Neighborhood Hits	808	Target Neighborhood Hits	1202	Shared Neighborhood Hits	107
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

ATL3_HUMAN
NC score	0.060910 (rank : 817)	θ value	4.03905 (rank : 655)
Query Neighborhood Hits	808	Target Neighborhood Hits	414	Shared Neighborhood Hits	91
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

KRA33_HUMAN
NC score	0.060805 (rank : 818)	θ value	θ > 10 (rank : 976)
Query Neighborhood Hits	808	Target Neighborhood Hits	53	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BYR6, Q52LP0	Gene names	KRTAP3-3, KAP3.3, KRTAP3.3
Domain Architecture
Description	Keratin-associated protein 3-3 (Keratin-associated protein 3.3) (High sulfur keratin-associated protein 3.3).

GPR64_HUMAN
NC score	0.060448 (rank : 819)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	808	Target Neighborhood Hits	207	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

MINT_MOUSE
NC score	0.060445 (rank : 820)	θ value	0.0330416 (rank : 344)
Query Neighborhood Hits	808	Target Neighborhood Hits	1514	Shared Neighborhood Hits	108
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

FURIN_HUMAN
NC score	0.060398 (rank : 821)	θ value	2.36792 (rank : 611)
Query Neighborhood Hits	808	Target Neighborhood Hits	52	Shared Neighborhood Hits	26
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

GGN_MOUSE
NC score	0.060381 (rank : 822)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	808	Target Neighborhood Hits	311	Shared Neighborhood Hits	54
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

HPLN3_HUMAN
NC score	0.060334 (rank : 823)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	808	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

NFRKB_HUMAN
NC score	0.060186 (rank : 824)	θ value	θ > 10 (rank : 1019)
Query Neighborhood Hits	808	Target Neighborhood Hits	211	Shared Neighborhood Hits	45
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

ATS3_HUMAN
NC score	0.060141 (rank : 825)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	808	Target Neighborhood Hits	179	Shared Neighborhood Hits	89
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS19_MOUSE
NC score	0.060111 (rank : 826)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	808	Target Neighborhood Hits	188	Shared Neighborhood Hits	87
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

SPR2A_MOUSE
NC score	0.059953 (rank : 827)	θ value	1.06291 (rank : 554)
Query Neighborhood Hits	808	Target Neighborhood Hits	35	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CQK8, O70553	Gene names	Sprr2a
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2A.

TCOF_HUMAN
NC score	0.059905 (rank : 828)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	808	Target Neighborhood Hits	543	Shared Neighborhood Hits	62
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

HPLN1_MOUSE
NC score	0.059679 (rank : 829)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	808	Target Neighborhood Hits	64	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN1_HUMAN
NC score	0.059632 (rank : 830)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	808	Target Neighborhood Hits	67	Shared Neighborhood Hits	15
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

GPR64_MOUSE
NC score	0.059560 (rank : 831)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	808	Target Neighborhood Hits	156	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

CO3A1_HUMAN
NC score	0.059329 (rank : 832)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	808	Target Neighborhood Hits	452	Shared Neighborhood Hits	69
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

HPLN4_MOUSE
NC score	0.059297 (rank : 833)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	808	Target Neighborhood Hits	98	Shared Neighborhood Hits	17
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

HPLN4_HUMAN
NC score	0.059254 (rank : 834)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	808	Target Neighborhood Hits	100	Shared Neighborhood Hits	17
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

ATS5_MOUSE
NC score	0.059243 (rank : 835)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	808	Target Neighborhood Hits	147	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

UROK_MOUSE
NC score	0.059120 (rank : 836)	θ value	θ > 10 (rank : 1128)
Query Neighborhood Hits	808	Target Neighborhood Hits	273	Shared Neighborhood Hits	101
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

RPB1_HUMAN
NC score	0.058946 (rank : 837)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	808	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

FREM2_MOUSE
NC score	0.058879 (rank : 838)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

SRPX_HUMAN
NC score	0.058860 (rank : 839)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	808	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

FREM1_HUMAN
NC score	0.058771 (rank : 840)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	808	Target Neighborhood Hits	170	Shared Neighborhood Hits	18
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

ATF2_HUMAN
NC score	0.058676 (rank : 841)	θ value	0.0431538 (rank : 348)
Query Neighborhood Hits	808	Target Neighborhood Hits	402	Shared Neighborhood Hits	32
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATS19_HUMAN
NC score	0.058662 (rank : 842)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	808	Target Neighborhood Hits	203	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

GP113_HUMAN
NC score	0.058621 (rank : 843)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

UROK_HUMAN
NC score	0.058476 (rank : 844)	θ value	θ > 10 (rank : 1127)
Query Neighborhood Hits	808	Target Neighborhood Hits	272	Shared Neighborhood Hits	97
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

RPB1_MOUSE
NC score	0.058470 (rank : 845)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	808	Target Neighborhood Hits	363	Shared Neighborhood Hits	49
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

CO6A3_HUMAN
NC score	0.058445 (rank : 846)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	808	Target Neighborhood Hits	317	Shared Neighborhood Hits	50
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

GPR98_MOUSE
NC score	0.058321 (rank : 847)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	808	Target Neighborhood Hits	206	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

CR1_HUMAN
NC score	0.058285 (rank : 848)	θ value	0.47712 (rank : 482)
Query Neighborhood Hits	808	Target Neighborhood Hits	108	Shared Neighborhood Hits	40
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

WASIP_HUMAN
NC score	0.058136 (rank : 849)	θ value	θ > 10 (rank : 1133)
Query Neighborhood Hits	808	Target Neighborhood Hits	458	Shared Neighborhood Hits	56
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

CSKI1_MOUSE
NC score	0.058094 (rank : 850)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	808	Target Neighborhood Hits	1031	Shared Neighborhood Hits	93
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

WFDC5_HUMAN
NC score	0.057983 (rank : 851)	θ value	5.27518 (rank : 714)
Query Neighborhood Hits	808	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TCV5, Q6UWE4	Gene names	WFDC5, WAP1
Domain Architecture
Description	WAP four-disulfide core domain protein 5 precursor (Putative protease inhibitor WAP1).

FA47A_HUMAN
NC score	0.057938 (rank : 852)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	808	Target Neighborhood Hits	451	Shared Neighborhood Hits	40
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

ELF4_MOUSE
NC score	0.057889 (rank : 853)	θ value	7.59969e-07 (rank : 117)
Query Neighborhood Hits	808	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

ATS15_HUMAN
NC score	0.057846 (rank : 854)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	808	Target Neighborhood Hits	151	Shared Neighborhood Hits	80
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

FREM2_HUMAN
NC score	0.057432 (rank : 855)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	808	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

KR221_HUMAN
NC score	0.057225 (rank : 856)	θ value	θ > 10 (rank : 974)
Query Neighborhood Hits	808	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.

ATS8_MOUSE
NC score	0.057219 (rank : 857)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	808	Target Neighborhood Hits	139	Shared Neighborhood Hits	68
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATF2_MOUSE
NC score	0.057072 (rank : 858)	θ value	0.0431538 (rank : 349)
Query Neighborhood Hits	808	Target Neighborhood Hits	397	Shared Neighborhood Hits	31
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

ATL2_HUMAN
NC score	0.056887 (rank : 859)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	808	Target Neighborhood Hits	125	Shared Neighborhood Hits	58
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

PCSK4_HUMAN
NC score	0.056696 (rank : 860)	θ value	8.99809 (rank : 792)
Query Neighborhood Hits	808	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

ATS4_MOUSE
NC score	0.056615 (rank : 861)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	808	Target Neighborhood Hits	145	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

PCLO_MOUSE
NC score	0.056563 (rank : 862)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	808	Target Neighborhood Hits	2275	Shared Neighborhood Hits	153
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CILP2_HUMAN
NC score	0.056278 (rank : 863)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	808	Target Neighborhood Hits	307	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

GRIN1_MOUSE
NC score	0.056200 (rank : 864)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	808	Target Neighborhood Hits	337	Shared Neighborhood Hits	49
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SRRM2_HUMAN
NC score	0.056054 (rank : 865)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	808	Target Neighborhood Hits	1296	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SF3A2_MOUSE
NC score	0.056049 (rank : 866)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	808	Target Neighborhood Hits	247	Shared Neighborhood Hits	41
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

DCC_MOUSE
NC score	0.055759 (rank : 867)	θ value	6.88961 (rank : 726)
Query Neighborhood Hits	808	Target Neighborhood Hits	896	Shared Neighborhood Hits	103
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

CR2_HUMAN
NC score	0.055655 (rank : 868)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	808	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

ZP2_HUMAN
NC score	0.055610 (rank : 869)	θ value	θ > 10 (rank : 1136)
Query Neighborhood Hits	808	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q05996	Gene names	ZP2, ZPA
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

ATS2_HUMAN
NC score	0.055590 (rank : 870)	θ value	8.99809 (rank : 765)
Query Neighborhood Hits	808	Target Neighborhood Hits	179	Shared Neighborhood Hits	82
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS5_HUMAN
NC score	0.055585 (rank : 871)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	808	Target Neighborhood Hits	141	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

GGN_HUMAN
NC score	0.055505 (rank : 872)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	808	Target Neighborhood Hits	269	Shared Neighborhood Hits	42
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MUCDL_MOUSE
NC score	0.055476 (rank : 873)	θ value	θ > 10 (rank : 1009)
Query Neighborhood Hits	808	Target Neighborhood Hits	461	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NOLC1_HUMAN
NC score	0.054466 (rank : 874)	θ value	θ > 10 (rank : 1021)
Query Neighborhood Hits	808	Target Neighborhood Hits	452	Shared Neighborhood Hits	46
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

SELV_HUMAN
NC score	0.054422 (rank : 875)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	808	Target Neighborhood Hits	118	Shared Neighborhood Hits	29
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

ATS2_MOUSE
NC score	0.054413 (rank : 876)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	808	Target Neighborhood Hits	179	Shared Neighborhood Hits	80
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

OVGP1_HUMAN
NC score	0.054388 (rank : 877)	θ value	0.00869519 (rank : 298)
Query Neighborhood Hits	808	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q12889, Q15841	Gene names	OVGP1, MUC9, OGP
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein) (Mucin 9).

FREM1_MOUSE
NC score	0.054373 (rank : 878)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	808	Target Neighborhood Hits	163	Shared Neighborhood Hits	15
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

HNF1A_HUMAN
NC score	0.054149 (rank : 879)	θ value	0.0431538 (rank : 354)
Query Neighborhood Hits	808	Target Neighborhood Hits	193	Shared Neighborhood Hits	29
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

SEM5A_MOUSE
NC score	0.053959 (rank : 880)	θ value	0.62314 (rank : 506)
Query Neighborhood Hits	808	Target Neighborhood Hits	162	Shared Neighborhood Hits	51
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

CDN2B_HUMAN
NC score	0.053943 (rank : 881)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	808	Target Neighborhood Hits	196	Shared Neighborhood Hits	11
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CSKI1_HUMAN
NC score	0.053893 (rank : 882)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	808	Target Neighborhood Hits	997	Shared Neighborhood Hits	84
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ZP2_MOUSE
NC score	0.053891 (rank : 883)	θ value	θ > 10 (rank : 1137)
Query Neighborhood Hits	808	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	P20239	Gene names	Zp2, Zp-2, Zpa
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

GPR98_HUMAN
NC score	0.053867 (rank : 884)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	808	Target Neighborhood Hits	202	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

NUP62_MOUSE
NC score	0.053867 (rank : 885)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	808	Target Neighborhood Hits	200	Shared Neighborhood Hits	30
SwissProt Accessions	Q63850, Q99JN7	Gene names	Nup62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

SPR2K_MOUSE
NC score	0.053817 (rank : 886)	θ value	5.27518 (rank : 705)
Query Neighborhood Hits	808	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	O70562	Gene names	Sprr2k
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2K.

CILP1_HUMAN
NC score	0.053666 (rank : 887)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	808	Target Neighborhood Hits	266	Shared Neighborhood Hits	50
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

HBEGF_HUMAN
NC score	0.053636 (rank : 888)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	808	Target Neighborhood Hits	61	Shared Neighborhood Hits	41
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

CILP1_MOUSE
NC score	0.053601 (rank : 889)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	808	Target Neighborhood Hits	282	Shared Neighborhood Hits	47
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CD2A1_MOUSE
NC score	0.053551 (rank : 890)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	808	Target Neighborhood Hits	206	Shared Neighborhood Hits	11
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

ECM2_HUMAN
NC score	0.053490 (rank : 891)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	808	Target Neighborhood Hits	402	Shared Neighborhood Hits	58
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

PDGFD_HUMAN
NC score	0.053472 (rank : 892)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	808	Target Neighborhood Hits	74	Shared Neighborhood Hits	26
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

ATS4_HUMAN
NC score	0.053359 (rank : 893)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	808	Target Neighborhood Hits	138	Shared Neighborhood Hits	69
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

BSN_HUMAN
NC score	0.053349 (rank : 894)	θ value	2.36792 (rank : 605)
Query Neighborhood Hits	808	Target Neighborhood Hits	1537	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BASP_MOUSE
NC score	0.053257 (rank : 895)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	808	Target Neighborhood Hits	260	Shared Neighborhood Hits	32
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

GP116_HUMAN
NC score	0.053110 (rank : 896)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	808	Target Neighborhood Hits	167	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

CR2_MOUSE
NC score	0.052985 (rank : 897)	θ value	6.88961 (rank : 725)
Query Neighborhood Hits	808	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

GP114_HUMAN
NC score	0.052882 (rank : 898)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	808	Target Neighborhood Hits	75	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

ATL2_MOUSE
NC score	0.052756 (rank : 899)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	808	Target Neighborhood Hits	137	Shared Neighborhood Hits	60
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

AKA12_HUMAN
NC score	0.052736 (rank : 900)	θ value	0.000461057 (rank : 206)
Query Neighborhood Hits	808	Target Neighborhood Hits	825	Shared Neighborhood Hits	49
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

RERE_MOUSE
NC score	0.052662 (rank : 901)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	808	Target Neighborhood Hits	785	Shared Neighborhood Hits	82
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

NSD1_MOUSE
NC score	0.052643 (rank : 902)	θ value	1.38821 (rank : 572)
Query Neighborhood Hits	808	Target Neighborhood Hits	472	Shared Neighborhood Hits	59
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

TRI42_HUMAN
NC score	0.052438 (rank : 903)	θ value	0.0961366 (rank : 396)
Query Neighborhood Hits	808	Target Neighborhood Hits	283	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

CFAB_MOUSE
NC score	0.052267 (rank : 904)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	808	Target Neighborhood Hits	262	Shared Neighborhood Hits	56
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CIC_MOUSE
NC score	0.052243 (rank : 905)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	808	Target Neighborhood Hits	742	Shared Neighborhood Hits	86
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DAG1_HUMAN
NC score	0.052158 (rank : 906)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	808	Target Neighborhood Hits	104	Shared Neighborhood Hits	38
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

INSRR_HUMAN
NC score	0.052102 (rank : 907)	θ value	1.06291 (rank : 541)
Query Neighborhood Hits	808	Target Neighborhood Hits	950	Shared Neighborhood Hits	137
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

TGFA_HUMAN
NC score	0.052093 (rank : 908)	θ value	θ > 10 (rank : 1100)
Query Neighborhood Hits	808	Target Neighborhood Hits	61	Shared Neighborhood Hits	42
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

MSMB_MOUSE
NC score	0.052054 (rank : 909)	θ value	5.27518 (rank : 699)
Query Neighborhood Hits	808	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	O08540	Gene names	Msmb, Psp94
Domain Architecture
Description	Beta-microseminoprotein precursor (Prostate secreted seminal plasma protein) (Prostate secretory protein PSP94) (PSP-94).

LPHN1_HUMAN
NC score	0.051980 (rank : 910)	θ value	θ > 10 (rank : 981)
Query Neighborhood Hits	808	Target Neighborhood Hits	155	Shared Neighborhood Hits	29
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

PRP1_HUMAN
NC score	0.051918 (rank : 911)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	808	Target Neighborhood Hits	385	Shared Neighborhood Hits	41
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

COCH_HUMAN
NC score	0.051895 (rank : 912)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	808	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

PF21B_MOUSE
NC score	0.051870 (rank : 913)	θ value	1.38821 (rank : 573)
Query Neighborhood Hits	808	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

GP144_HUMAN
NC score	0.051850 (rank : 914)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	808	Target Neighborhood Hits	108	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

COCH_MOUSE
NC score	0.051746 (rank : 915)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	808	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

ALEX_HUMAN
NC score	0.051705 (rank : 916)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	808	Target Neighborhood Hits	361	Shared Neighborhood Hits	48
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CS016_HUMAN
NC score	0.051595 (rank : 917)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	808	Target Neighborhood Hits	310	Shared Neighborhood Hits	59
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

THYG_HUMAN
NC score	0.051592 (rank : 918)	θ value	0.813845 (rank : 525)
Query Neighborhood Hits	808	Target Neighborhood Hits	154	Shared Neighborhood Hits	60
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

TR19L_MOUSE
NC score	0.051544 (rank : 919)	θ value	θ > 10 (rank : 1123)
Query Neighborhood Hits	808	Target Neighborhood Hits	85	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

EREG_MOUSE
NC score	0.051495 (rank : 920)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	808	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

PTPRB_HUMAN
NC score	0.051229 (rank : 921)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	808	Target Neighborhood Hits	242	Shared Neighborhood Hits	36
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

VITRN_MOUSE
NC score	0.051224 (rank : 922)	θ value	θ > 10 (rank : 1132)
Query Neighborhood Hits	808	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

RERE_HUMAN
NC score	0.051212 (rank : 923)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	808	Target Neighborhood Hits	779	Shared Neighborhood Hits	90
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

LPHN2_HUMAN
NC score	0.051130 (rank : 924)	θ value	θ > 10 (rank : 982)
Query Neighborhood Hits	808	Target Neighborhood Hits	136	Shared Neighborhood Hits	24
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

CI094_HUMAN
NC score	0.051009 (rank : 925)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	808	Target Neighborhood Hits	310	Shared Neighborhood Hits	49
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

GP133_HUMAN
NC score	0.050981 (rank : 926)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	808	Target Neighborhood Hits	115	Shared Neighborhood Hits	18
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

PDGFD_MOUSE
NC score	0.050538 (rank : 927)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	808	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

TR19L_HUMAN
NC score	0.050515 (rank : 928)	θ value	θ > 10 (rank : 1122)
Query Neighborhood Hits	808	Target Neighborhood Hits	99	Shared Neighborhood Hits	46
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

FREM3_HUMAN
NC score	0.050510 (rank : 929)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	808	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

PTPRS_HUMAN
NC score	0.050466 (rank : 930)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	808	Target Neighborhood Hits	472	Shared Neighborhood Hits	60
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

CD45_HUMAN
NC score	0.050453 (rank : 931)	θ value	0.0431538 (rank : 350)
Query Neighborhood Hits	808	Target Neighborhood Hits	243	Shared Neighborhood Hits	48
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

GP110_MOUSE
NC score	0.050368 (rank : 932)	θ value	3.0926 (rank : 637)
Query Neighborhood Hits	808	Target Neighborhood Hits	92	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

INSRR_MOUSE
NC score	0.050284 (rank : 933)	θ value	0.365318 (rank : 468)
Query Neighborhood Hits	808	Target Neighborhood Hits	961	Shared Neighborhood Hits	152
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

FREM3_MOUSE
NC score	0.050229 (rank : 934)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	808	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

IBP7_MOUSE
NC score	0.050192 (rank : 935)	θ value	1.81305 (rank : 585)
Query Neighborhood Hits	808	Target Neighborhood Hits	230	Shared Neighborhood Hits	54
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

MARCS_HUMAN
NC score	0.050117 (rank : 936)	θ value	θ > 10 (rank : 990)
Query Neighborhood Hits	808	Target Neighborhood Hits	204	Shared Neighborhood Hits	30
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

LPHN3_HUMAN
NC score	0.050080 (rank : 937)	θ value	θ > 10 (rank : 983)
Query Neighborhood Hits	808	Target Neighborhood Hits	139	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

SPRR3_HUMAN
NC score	0.050051 (rank : 938)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	808	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

ANR38_MOUSE
NC score	0.050049 (rank : 939)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	808	Target Neighborhood Hits	512	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

PRAX_MOUSE
NC score	0.050041 (rank : 940)	θ value	2.36792 (rank : 622)
Query Neighborhood Hits	808	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SPY4_MOUSE
NC score	0.049351 (rank : 941)	θ value	1.81305 (rank : 593)
Query Neighborhood Hits	808	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

EZH1_MOUSE
NC score	0.049337 (rank : 942)	θ value	0.62314 (rank : 499)
Query Neighborhood Hits	808	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

PARM1_HUMAN
NC score	0.048668 (rank : 943)	θ value	8.99809 (rank : 791)
Query Neighborhood Hits	808	Target Neighborhood Hits	86	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UWI2, Q96DV8, Q9Y4S1	Gene names	ames=UNQ1879/PRO4322
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

LY6D_MOUSE
NC score	0.048426 (rank : 944)	θ value	0.0431538 (rank : 357)
Query Neighborhood Hits	808	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	P35459	Gene names	Ly6d, Ly61, Thb
Domain Architecture
Description	Lymphocyte antigen Ly-6D precursor (Thymocyte B-cell antigen) (ThB).

SYNPO_HUMAN
NC score	0.048296 (rank : 945)	θ value	0.163984 (rank : 422)
Query Neighborhood Hits	808	Target Neighborhood Hits	281	Shared Neighborhood Hits	47
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

CSPG5_HUMAN
NC score	0.047351 (rank : 946)	θ value	5.27518 (rank : 687)
Query Neighborhood Hits	808	Target Neighborhood Hits	199	Shared Neighborhood Hits	38
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

SEPP1_MOUSE
NC score	0.046851 (rank : 947)	θ value	0.279714 (rank : 454)
Query Neighborhood Hits	808	Target Neighborhood Hits	35	Shared Neighborhood Hits	28
SwissProt Accessions	P70274, Q9Z2T7	Gene names	Sepp1, Selp
Domain Architecture
Description	Selenoprotein P precursor (SeP) (Plasma selenoprotein P).

OVGP1_MOUSE
NC score	0.046802 (rank : 948)	θ value	1.43324e-05 (rank : 152)
Query Neighborhood Hits	808	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	Q62010	Gene names	Ovgp1, Chit5, Ogp
Domain Architecture
Description	Oviduct-specific glycoprotein precursor (Oviductal glycoprotein) (Oviductin) (Estrogen-dependent oviduct protein).

DCP1A_HUMAN
NC score	0.046676 (rank : 949)	θ value	4.03905 (rank : 659)
Query Neighborhood Hits	808	Target Neighborhood Hits	228	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

RGS3_MOUSE
NC score	0.046670 (rank : 950)	θ value	6.88961 (rank : 754)
Query Neighborhood Hits	808	Target Neighborhood Hits	1621	Shared Neighborhood Hits	122
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SPY1_HUMAN
NC score	0.046267 (rank : 951)	θ value	3.0926 (rank : 646)
Query Neighborhood Hits	808	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

EZH1_HUMAN
NC score	0.045559 (rank : 952)	θ value	0.62314 (rank : 498)
Query Neighborhood Hits	808	Target Neighborhood Hits	121	Shared Neighborhood Hits	51
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

ALK1_HUMAN
NC score	0.045147 (rank : 953)	θ value	0.62314 (rank : 495)
Query Neighborhood Hits	808	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	P03973, P07757	Gene names	SLPI, WAP4, WFDC4
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (HUSI-1) (Seminal proteinase inhibitor) (Secretory leukocyte protease inhibitor) (BLPI) (Mucus proteinase inhibitor) (MPI) (WAP four-disulfide core domain protein 4) (Protease inhibitor WAP4).

GP123_HUMAN
NC score	0.045144 (rank : 954)	θ value	3.0926 (rank : 638)
Query Neighborhood Hits	808	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

COFA1_MOUSE
NC score	0.045028 (rank : 955)	θ value	0.0736092 (rank : 376)
Query Neighborhood Hits	808	Target Neighborhood Hits	305	Shared Neighborhood Hits	40
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

TGFA_MOUSE
NC score	0.044785 (rank : 956)	θ value	8.99809 (rank : 803)
Query Neighborhood Hits	808	Target Neighborhood Hits	62	Shared Neighborhood Hits	38
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

IGF1R_MOUSE
NC score	0.044402 (rank : 957)	θ value	0.365318 (rank : 467)
Query Neighborhood Hits	808	Target Neighborhood Hits	973	Shared Neighborhood Hits	151
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IMPG1_MOUSE
NC score	0.043952 (rank : 958)	θ value	0.47712 (rank : 484)
Query Neighborhood Hits	808	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).

THYG_MOUSE
NC score	0.043050 (rank : 959)	θ value	5.27518 (rank : 706)
Query Neighborhood Hits	808	Target Neighborhood Hits	161	Shared Neighborhood Hits	69
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TITIN_HUMAN
NC score	0.043050 (rank : 960)	θ value	0.163984 (rank : 423)
Query Neighborhood Hits	808	Target Neighborhood Hits	2923	Shared Neighborhood Hits	198
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MAP2_MOUSE
NC score	0.042907 (rank : 961)	θ value	4.03905 (rank : 669)
Query Neighborhood Hits	808	Target Neighborhood Hits	342	Shared Neighborhood Hits	38
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

IGF1R_HUMAN
NC score	0.042818 (rank : 962)	θ value	0.163984 (rank : 415)
Query Neighborhood Hits	808	Target Neighborhood Hits	977	Shared Neighborhood Hits	155
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

CEL_HUMAN
NC score	0.042488 (rank : 963)	θ value	0.0736092 (rank : 375)
Query Neighborhood Hits	808	Target Neighborhood Hits	896	Shared Neighborhood Hits	69
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

HYAL3_MOUSE
NC score	0.042139 (rank : 964)	θ value	1.38821 (rank : 564)
Query Neighborhood Hits	808	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

BCL9_HUMAN
NC score	0.041798 (rank : 965)	θ value	8.99809 (rank : 767)
Query Neighborhood Hits	808	Target Neighborhood Hits	1008	Shared Neighborhood Hits	83
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

ALMS1_MOUSE
NC score	0.041520 (rank : 966)	θ value	1.06291 (rank : 529)
Query Neighborhood Hits	808	Target Neighborhood Hits	181	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

HNF1A_MOUSE
NC score	0.041517 (rank : 967)	θ value	5.27518 (rank : 695)
Query Neighborhood Hits	808	Target Neighborhood Hits	212	Shared Neighborhood Hits	28
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

NFH_MOUSE
NC score	0.041493 (rank : 968)	θ value	5.44631e-05 (rank : 169)
Query Neighborhood Hits	808	Target Neighborhood Hits	2247	Shared Neighborhood Hits	123
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

INSR_HUMAN
NC score	0.041026 (rank : 969)	θ value	0.0330416 (rank : 343)
Query Neighborhood Hits	808	Target Neighborhood Hits	963	Shared Neighborhood Hits	135
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

GON4L_MOUSE
NC score	0.040963 (rank : 970)	θ value	0.163984 (rank : 414)
Query Neighborhood Hits	808	Target Neighborhood Hits	455	Shared Neighborhood Hits	52
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

COGA1_HUMAN
NC score	0.040847 (rank : 971)	θ value	3.0926 (rank : 634)
Query Neighborhood Hits	808	Target Neighborhood Hits	345	Shared Neighborhood Hits	46
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

SPY3_HUMAN
NC score	0.040520 (rank : 972)	θ value	6.88961 (rank : 756)
Query Neighborhood Hits	808	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	O43610	Gene names	SPRY3
Domain Architecture
Description	Sprouty homolog 3 (Spry-3).

HYAL3_HUMAN
NC score	0.040087 (rank : 973)	θ value	1.06291 (rank : 539)
Query Neighborhood Hits	808	Target Neighborhood Hits	45	Shared Neighborhood Hits	36
SwissProt Accessions	O43820, O60540, Q8NFK2, Q8NFK3, Q8NFK4, Q96E56, Q9BRW9	Gene names	HYAL3, LUCA3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3) (LUCA-3).

INSR_MOUSE
NC score	0.039652 (rank : 974)	θ value	0.00509761 (rank : 272)
Query Neighborhood Hits	808	Target Neighborhood Hits	968	Shared Neighborhood Hits	134
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

PER3_HUMAN
NC score	0.039259 (rank : 975)	θ value	8.99809 (rank : 793)
Query Neighborhood Hits	808	Target Neighborhood Hits	479	Shared Neighborhood Hits	45
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

ATL1_MOUSE
NC score	0.038593 (rank : 976)	θ value	1.06291 (rank : 531)
Query Neighborhood Hits	808	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

INVS_MOUSE
NC score	0.038448 (rank : 977)	θ value	6.88961 (rank : 735)
Query Neighborhood Hits	808	Target Neighborhood Hits	609	Shared Neighborhood Hits	32
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

PG12A_HUMAN
NC score	0.037985 (rank : 978)	θ value	0.47712 (rank : 488)
Query Neighborhood Hits	808	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZM1, Q9BZ89	Gene names	PLA2G12A, PLA2G12
Domain Architecture
Description	Group XIIA secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GXII) (GXII sPLA2).

EZH2_MOUSE
NC score	0.037835 (rank : 979)	θ value	4.03905 (rank : 662)
Query Neighborhood Hits	808	Target Neighborhood Hits	86	Shared Neighborhood Hits	40
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

INVS_HUMAN
NC score	0.037019 (rank : 980)	θ value	6.88961 (rank : 734)
Query Neighborhood Hits	808	Target Neighborhood Hits	455	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

EZH2_HUMAN
NC score	0.036993 (rank : 981)	θ value	4.03905 (rank : 661)
Query Neighborhood Hits	808	Target Neighborhood Hits	84	Shared Neighborhood Hits	38
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

FHR1_HUMAN
NC score	0.036972 (rank : 982)	θ value	8.99809 (rank : 775)
Query Neighborhood Hits	808	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

PTPRO_HUMAN
NC score	0.036940 (rank : 983)	θ value	1.81305 (rank : 591)
Query Neighborhood Hits	808	Target Neighborhood Hits	139	Shared Neighborhood Hits	26
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

KALM_HUMAN
NC score	0.035698 (rank : 984)	θ value	4.03905 (rank : 668)
Query Neighborhood Hits	808	Target Neighborhood Hits	114	Shared Neighborhood Hits	33
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

AL2SA_HUMAN
NC score	0.035674 (rank : 985)	θ value	0.125558 (rank : 399)
Query Neighborhood Hits	808	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	Q53TS8, Q8NCN6, Q96LN4	Gene names	ALS2CR11
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein.

GFRAL_MOUSE
NC score	0.035607 (rank : 986)	θ value	4.03905 (rank : 663)
Query Neighborhood Hits	808	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

PG12A_MOUSE
NC score	0.033988 (rank : 987)	θ value	0.365318 (rank : 473)
Query Neighborhood Hits	808	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPR2, Q3TQC4, Q9CQR3, Q9CTL1, Q9D7L3, Q9EPR1	Gene names	Pla2g12a, Pla2g12
Domain Architecture
Description	Group XIIA secretory phospholipase A2 precursor (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase GXII) (GXII sPLA2).

BRD8_MOUSE
NC score	0.033783 (rank : 988)	θ value	2.36792 (rank : 604)
Query Neighborhood Hits	808	Target Neighborhood Hits	422	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

ERBB3_HUMAN
NC score	0.033070 (rank : 989)	θ value	5.27518 (rank : 689)
Query Neighborhood Hits	808	Target Neighborhood Hits	918	Shared Neighborhood Hits	122
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

FLIP1_MOUSE
NC score	0.032622 (rank : 990)	θ value	0.000461057 (rank : 209)
Query Neighborhood Hits	808	Target Neighborhood Hits	1176	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

ROBO3_HUMAN
NC score	0.032436 (rank : 991)	θ value	8.99809 (rank : 799)
Query Neighborhood Hits	808	Target Neighborhood Hits	570	Shared Neighborhood Hits	65
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

NPAS4_HUMAN
NC score	0.032079 (rank : 992)	θ value	8.99809 (rank : 788)
Query Neighborhood Hits	808	Target Neighborhood Hits	214	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

PF21A_HUMAN
NC score	0.032021 (rank : 993)	θ value	0.47712 (rank : 487)
Query Neighborhood Hits	808	Target Neighborhood Hits	303	Shared Neighborhood Hits	32
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

COFA1_HUMAN
NC score	0.031915 (rank : 994)	θ value	6.88961 (rank : 724)
Query Neighborhood Hits	808	Target Neighborhood Hits	292	Shared Neighborhood Hits	39
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

TAF9B_HUMAN
NC score	0.031502 (rank : 995)	θ value	0.813845 (rank : 524)
Query Neighborhood Hits	808	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HBM6, Q9Y2S3	Gene names	TAF9B, TAF9L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 9B (Transcription initiation factor TFIID subunit 9-like protein) (Transcription- associated factor TAFII31L) (Neuronal cell death-related protein 7) (DN-7).

LY6D_HUMAN
NC score	0.030682 (rank : 996)	θ value	1.81305 (rank : 589)
Query Neighborhood Hits	808	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q14210, O43783, Q8TBD4, Q92933	Gene names	LY6D, E48
Domain Architecture
Description	Lymphocyte antigen Ly-6D precursor (E48 antigen).

VEGFD_HUMAN
NC score	0.030318 (rank : 997)	θ value	6.88961 (rank : 759)
Query Neighborhood Hits	808	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	O43915	Gene names	FIGF, VEGFD
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

AQR_HUMAN
NC score	0.029959 (rank : 998)	θ value	1.06291 (rank : 530)
Query Neighborhood Hits	808	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

CABYR_HUMAN
NC score	0.029730 (rank : 999)	θ value	1.06291 (rank : 533)
Query Neighborhood Hits	808	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

FAM5B_MOUSE
NC score	0.029724 (rank : 1000)	θ value	5.27518 (rank : 691)
Query Neighborhood Hits	808	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

LY6H_HUMAN
NC score	0.029627 (rank : 1001)	θ value	0.813845 (rank : 518)
Query Neighborhood Hits	808	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	O94772	Gene names	LY6H
Domain Architecture
Description	Lymphocyte antigen Ly-6H precursor.

PCSK9_HUMAN
NC score	0.028612 (rank : 1002)	θ value	0.21417 (rank : 437)
Query Neighborhood Hits	808	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NBP7, Q5PSM5	Gene names	PCSK9, NARC1
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 9 precursor (EC 3.4.21.-) (Proprotein convertase PC9) (Subtilisin/kexin-like protease PC9) (Neural apoptosis-regulated convertase 1) (NARC-1).

MAP1A_HUMAN
NC score	0.028599 (rank : 1003)	θ value	1.06291 (rank : 547)
Query Neighborhood Hits	808	Target Neighborhood Hits	1626	Shared Neighborhood Hits	74
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PALB2_MOUSE
NC score	0.028439 (rank : 1004)	θ value	3.0926 (rank : 642)
Query Neighborhood Hits	808	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

RXFP2_MOUSE
NC score	0.027590 (rank : 1005)	θ value	8.99809 (rank : 800)
Query Neighborhood Hits	808	Target Neighborhood Hits	760	Shared Neighborhood Hits	50
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

FLIP1_HUMAN
NC score	0.027353 (rank : 1006)	θ value	0.000121331 (rank : 179)
Query Neighborhood Hits	808	Target Neighborhood Hits	1405	Shared Neighborhood Hits	44
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

TACC2_HUMAN
NC score	0.027263 (rank : 1007)	θ value	2.36792 (rank : 625)
Query Neighborhood Hits	808	Target Neighborhood Hits	856	Shared Neighborhood Hits	63
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

FAM5B_HUMAN
NC score	0.025733 (rank : 1008)	θ value	5.27518 (rank : 690)
Query Neighborhood Hits	808	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

LPP_HUMAN
NC score	0.025730 (rank : 1009)	θ value	6.88961 (rank : 739)
Query Neighborhood Hits	808	Target Neighborhood Hits	775	Shared Neighborhood Hits	53
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

NFAC1_HUMAN
NC score	0.025667 (rank : 1010)	θ value	4.03905 (rank : 671)
Query Neighborhood Hits	808	Target Neighborhood Hits	312	Shared Neighborhood Hits	44
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

EGFR_HUMAN
NC score	0.025144 (rank : 1011)	θ value	3.0926 (rank : 635)
Query Neighborhood Hits	808	Target Neighborhood Hits	939	Shared Neighborhood Hits	121
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EPHB6_HUMAN
NC score	0.024974 (rank : 1012)	θ value	1.06291 (rank : 538)
Query Neighborhood Hits	808	Target Neighborhood Hits	912	Shared Neighborhood Hits	112
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

HSF1_MOUSE
NC score	0.024926 (rank : 1013)	θ value	6.88961 (rank : 733)
Query Neighborhood Hits	808	Target Neighborhood Hits	267	Shared Neighborhood Hits	18
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

K0586_HUMAN
NC score	0.024425 (rank : 1014)	θ value	5.27518 (rank : 696)
Query Neighborhood Hits	808	Target Neighborhood Hits	311	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

TXND2_MOUSE
NC score	0.024406 (rank : 1015)	θ value	5.27518 (rank : 711)
Query Neighborhood Hits	808	Target Neighborhood Hits	828	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

LCP2_HUMAN
NC score	0.024202 (rank : 1016)	θ value	2.36792 (rank : 615)
Query Neighborhood Hits	808	Target Neighborhood Hits	531	Shared Neighborhood Hits	40
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

X3CL1_MOUSE
NC score	0.024150 (rank : 1017)	θ value	1.81305 (rank : 598)
Query Neighborhood Hits	808	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	O35188, O35933	Gene names	Cx3cl1, Cx3c, Fkn, Scyd1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

SOX30_HUMAN
NC score	0.023977 (rank : 1018)	θ value	2.36792 (rank : 624)
Query Neighborhood Hits	808	Target Neighborhood Hits	305	Shared Neighborhood Hits	30
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

EPHB4_MOUSE
NC score	0.023695 (rank : 1019)	θ value	8.99809 (rank : 774)
Query Neighborhood Hits	808	Target Neighborhood Hits	1013	Shared Neighborhood Hits	139
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

ERBB4_HUMAN
NC score	0.023683 (rank : 1020)	θ value	6.88961 (rank : 730)
Query Neighborhood Hits	808	Target Neighborhood Hits	910	Shared Neighborhood Hits	103
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

ADDB_MOUSE
NC score	0.023633 (rank : 1021)	θ value	1.06291 (rank : 528)
Query Neighborhood Hits	808	Target Neighborhood Hits	574	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

OC90_HUMAN
NC score	0.023155 (rank : 1022)	θ value	6.88961 (rank : 751)
Query Neighborhood Hits	808	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	Q02509	Gene names	OC90, PLA2L
Domain Architecture
Description	Otoconin 90 precursor (Oc90) (Phospholipase A2 homolog).

ZN185_MOUSE
NC score	0.023114 (rank : 1023)	θ value	1.81305 (rank : 600)
Query Neighborhood Hits	808	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q62394	Gene names	Znf185, Zfp185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein Zfp185) (P1-A).

IBRD2_MOUSE
NC score	0.023090 (rank : 1024)	θ value	0.279714 (rank : 451)
Query Neighborhood Hits	808	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

TACC3_HUMAN
NC score	0.022765 (rank : 1025)	θ value	0.21417 (rank : 439)
Query Neighborhood Hits	808	Target Neighborhood Hits	779	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

PLXB1_HUMAN
NC score	0.022387 (rank : 1026)	θ value	4.03905 (rank : 673)
Query Neighborhood Hits	808	Target Neighborhood Hits	360	Shared Neighborhood Hits	49
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

ERBB2_MOUSE
NC score	0.021800 (rank : 1027)	θ value	0.0961366 (rank : 387)
Query Neighborhood Hits	808	Target Neighborhood Hits	918	Shared Neighborhood Hits	89
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

GAS1_HUMAN
NC score	0.021377 (rank : 1028)	θ value	5.27518 (rank : 692)
Query Neighborhood Hits	808	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P54826	Gene names	GAS1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

EGFR_MOUSE
NC score	0.021367 (rank : 1029)	θ value	0.813845 (rank : 514)
Query Neighborhood Hits	808	Target Neighborhood Hits	927	Shared Neighborhood Hits	107
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

GFRAL_HUMAN
NC score	0.021102 (rank : 1030)	θ value	5.27518 (rank : 693)
Query Neighborhood Hits	808	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UXV0, Q5VTF6	Gene names	GFRAL
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

IBRD2_HUMAN
NC score	0.020769 (rank : 1031)	θ value	0.21417 (rank : 430)
Query Neighborhood Hits	808	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

CDAN1_HUMAN
NC score	0.020768 (rank : 1032)	θ value	8.99809 (rank : 768)
Query Neighborhood Hits	808	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

ASXL1_MOUSE
NC score	0.020381 (rank : 1033)	θ value	4.03905 (rank : 654)
Query Neighborhood Hits	808	Target Neighborhood Hits	182	Shared Neighborhood Hits	16
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

GAS1_MOUSE
NC score	0.019938 (rank : 1034)	θ value	8.99809 (rank : 777)
Query Neighborhood Hits	808	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q01721	Gene names	Gas1, Gas-1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

CU063_MOUSE
NC score	0.019360 (rank : 1035)	θ value	0.62314 (rank : 496)
Query Neighborhood Hits	808	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P58659	Gene names
Domain Architecture
Description	Protein C21orf63 homolog precursor.

TICN3_HUMAN
NC score	0.019021 (rank : 1036)	θ value	8.99809 (rank : 804)
Query Neighborhood Hits	808	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

ELF4_HUMAN
NC score	0.018763 (rank : 1037)	θ value	6.88961 (rank : 728)
Query Neighborhood Hits	808	Target Neighborhood Hits	87	Shared Neighborhood Hits	13
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

NGL1_HUMAN
NC score	0.018447 (rank : 1038)	θ value	0.813845 (rank : 521)
Query Neighborhood Hits	808	Target Neighborhood Hits	511	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_MOUSE
NC score	0.018174 (rank : 1039)	θ value	1.06291 (rank : 552)
Query Neighborhood Hits	808	Target Neighborhood Hits	512	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

PALB2_HUMAN
NC score	0.017563 (rank : 1040)	θ value	4.03905 (rank : 672)
Query Neighborhood Hits	808	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

TULP4_HUMAN
NC score	0.017274 (rank : 1041)	θ value	1.81305 (rank : 597)
Query Neighborhood Hits	808	Target Neighborhood Hits	426	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

SVIL_MOUSE
NC score	0.016611 (rank : 1042)	θ value	8.99809 (rank : 802)
Query Neighborhood Hits	808	Target Neighborhood Hits	439	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

ZHX1_MOUSE
NC score	0.016574 (rank : 1043)	θ value	1.81305 (rank : 599)
Query Neighborhood Hits	808	Target Neighborhood Hits	334	Shared Neighborhood Hits	16
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

DGKH_HUMAN
NC score	0.016163 (rank : 1044)	θ value	0.62314 (rank : 497)
Query Neighborhood Hits	808	Target Neighborhood Hits	255	Shared Neighborhood Hits	19
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

WWP1_HUMAN
NC score	0.016030 (rank : 1045)	θ value	0.0563607 (rank : 373)
Query Neighborhood Hits	808	Target Neighborhood Hits	262	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

ATX7_MOUSE
NC score	0.015876 (rank : 1046)	θ value	6.88961 (rank : 720)
Query Neighborhood Hits	808	Target Neighborhood Hits	328	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

HMGA2_MOUSE
NC score	0.015703 (rank : 1047)	θ value	8.99809 (rank : 781)
Query Neighborhood Hits	808	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	P52927, Q3UQW0	Gene names	Hmga2, Hmgic
Domain Architecture	No domain graphic available
Description	High mobility group protein HMGI-C (High mobility group AT-hook protein 2).

DGKD_HUMAN
NC score	0.015357 (rank : 1048)	θ value	0.365318 (rank : 465)
Query Neighborhood Hits	808	Target Neighborhood Hits	231	Shared Neighborhood Hits	15
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

SMG7_MOUSE
NC score	0.015189 (rank : 1049)	θ value	4.03905 (rank : 676)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	20
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

GP156_MOUSE
NC score	0.015133 (rank : 1050)	θ value	4.03905 (rank : 664)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

GTF2I_HUMAN
NC score	0.014927 (rank : 1051)	θ value	8.99809 (rank : 778)
Query Neighborhood Hits	808	Target Neighborhood Hits	151	Shared Neighborhood Hits	10
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

TIP60_MOUSE
NC score	0.014889 (rank : 1052)	θ value	2.36792 (rank : 626)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

PHF12_HUMAN
NC score	0.014818 (rank : 1053)	θ value	8.99809 (rank : 794)
Query Neighborhood Hits	808	Target Neighborhood Hits	174	Shared Neighborhood Hits	24
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

LRRC4_HUMAN
NC score	0.014631 (rank : 1054)	θ value	6.88961 (rank : 742)
Query Neighborhood Hits	808	Target Neighborhood Hits	444	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

IL6_MOUSE
NC score	0.014522 (rank : 1055)	θ value	4.03905 (rank : 666)
Query Neighborhood Hits	808	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	P08505, Q3UCQ0, Q8BN26	Gene names	Il6, Il-6
Domain Architecture
Description	Interleukin-6 precursor (IL-6) (Interleukin HP-1) (B-cell hybridoma growth factor).

SEBP2_HUMAN
NC score	0.014333 (rank : 1056)	θ value	2.36792 (rank : 623)
Query Neighborhood Hits	808	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T21, Q8IYC0	Gene names	SECISBP2, SBP2
Domain Architecture
Description	SECIS-binding protein 2 (Selenocysteine insertion sequence-binding protein 2).

CD017_HUMAN
NC score	0.013728 (rank : 1057)	θ value	6.88961 (rank : 721)
Query Neighborhood Hits	808	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q53FE4, Q6FI84, Q6IS77, Q9H0D9	Gene names	C4orf17
Domain Architecture	No domain graphic available
Description	Protein C4orf17.

ZHX1_HUMAN
NC score	0.013586 (rank : 1058)	θ value	2.36792 (rank : 630)
Query Neighborhood Hits	808	Target Neighborhood Hits	307	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKY1, Q8IWD8	Gene names	ZHX1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

UBP28_MOUSE
NC score	0.013076 (rank : 1059)	θ value	0.279714 (rank : 457)
Query Neighborhood Hits	808	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

TIP60_HUMAN
NC score	0.012978 (rank : 1060)	θ value	5.27518 (rank : 707)
Query Neighborhood Hits	808	Target Neighborhood Hits	90	Shared Neighborhood Hits	17
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

CADH3_MOUSE
NC score	0.012809 (rank : 1061)	θ value	2.36792 (rank : 606)
Query Neighborhood Hits	808	Target Neighborhood Hits	160	Shared Neighborhood Hits	15
SwissProt Accessions	P10287, Q61465	Gene names	Cdh3, Cdhp
Domain Architecture
Description	Cadherin-3 precursor (Placental-cadherin) (P-cadherin).

RP1_HUMAN
NC score	0.012431 (rank : 1062)	θ value	0.813845 (rank : 523)
Query Neighborhood Hits	808	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	P56715	Gene names	RP1, ORP1
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein) (Retinitis pigmentosa 1 protein).

DSG2_MOUSE
NC score	0.012254 (rank : 1063)	θ value	8.99809 (rank : 771)
Query Neighborhood Hits	808	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	O55111, Q8K069, Q8R517	Gene names	Dsg2
Domain Architecture
Description	Desmoglein-2 precursor.

PRP40_MOUSE
NC score	0.012076 (rank : 1064)	θ value	5.27518 (rank : 701)
Query Neighborhood Hits	808	Target Neighborhood Hits	447	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

TNR17_HUMAN
NC score	0.011984 (rank : 1065)	θ value	6.88961 (rank : 757)
Query Neighborhood Hits	808	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q02223	Gene names	TNFRSF17, BCM, BCMA
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD269 antigen).

TS1R2_MOUSE
NC score	0.011863 (rank : 1066)	θ value	0.0961366 (rank : 397)
Query Neighborhood Hits	808	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

CADH3_HUMAN
NC score	0.011846 (rank : 1067)	θ value	5.27518 (rank : 685)
Query Neighborhood Hits	808	Target Neighborhood Hits	159	Shared Neighborhood Hits	12
SwissProt Accessions	P22223	Gene names	CDH3, CDHP
Domain Architecture
Description	Cadherin-3 precursor (Placental-cadherin) (P-cadherin).

EPHB3_HUMAN
NC score	0.011784 (rank : 1068)	θ value	3.0926 (rank : 636)
Query Neighborhood Hits	808	Target Neighborhood Hits	996	Shared Neighborhood Hits	94
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

K1958_MOUSE
NC score	0.011723 (rank : 1069)	θ value	6.88961 (rank : 736)
Query Neighborhood Hits	808	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C4P0, Q8BN62, Q8K1X8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1958 homolog.

TTLL5_MOUSE
NC score	0.011403 (rank : 1070)	θ value	1.38821 (rank : 579)
Query Neighborhood Hits	808	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

VMDL3_HUMAN
NC score	0.011246 (rank : 1071)	θ value	1.38821 (rank : 580)
Query Neighborhood Hits	808	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N1M1, Q8N356, Q8NFT9, Q9BR80	Gene names	VMD2L3
Domain Architecture
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

PARC_MOUSE
NC score	0.010956 (rank : 1072)	θ value	8.99809 (rank : 790)
Query Neighborhood Hits	808	Target Neighborhood Hits	114	Shared Neighborhood Hits	14
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

PO6F1_MOUSE
NC score	0.010861 (rank : 1073)	θ value	8.99809 (rank : 796)
Query Neighborhood Hits	808	Target Neighborhood Hits	581	Shared Neighborhood Hits	29
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

GTF2I_MOUSE
NC score	0.010712 (rank : 1074)	θ value	8.99809 (rank : 779)
Query Neighborhood Hits	808	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

SENP7_HUMAN
NC score	0.010639 (rank : 1075)	θ value	4.03905 (rank : 675)
Query Neighborhood Hits	808	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BQF6, Q96PS5, Q9C0F6, Q9HBT5	Gene names	SENP7, KIAA1707, SSP2, SUSP2
Domain Architecture
Description	Sentrin-specific protease 7 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP7) (SUMO-1-specific protease 2).

EPHA4_MOUSE
NC score	0.010566 (rank : 1076)	θ value	6.88961 (rank : 729)
Query Neighborhood Hits	808	Target Neighborhood Hits	982	Shared Neighborhood Hits	93
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

NAT6_HUMAN
NC score	0.010309 (rank : 1077)	θ value	6.88961 (rank : 749)
Query Neighborhood Hits	808	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q93015, Q93014	Gene names	NAT6, FUS2
Domain Architecture
Description	N-acetyltransferase 6 (EC 2.3.1.-) (Fus-2 protein) (Fusion 2 protein).

EPHB3_MOUSE
NC score	0.009976 (rank : 1078)	θ value	5.27518 (rank : 688)
Query Neighborhood Hits	808	Target Neighborhood Hits	996	Shared Neighborhood Hits	93
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

RKHD1_HUMAN
NC score	0.009689 (rank : 1079)	θ value	8.99809 (rank : 798)
Query Neighborhood Hits	808	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

NBR1_MOUSE
NC score	0.009658 (rank : 1080)	θ value	4.03905 (rank : 670)
Query Neighborhood Hits	808	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

DCR1A_HUMAN
NC score	0.009639 (rank : 1081)	θ value	2.36792 (rank : 610)
Query Neighborhood Hits	808	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PJP8, Q14701, Q6P5Y3, Q6PKL4	Gene names	DCLRE1A, KIAA0086, SNM1, SNM1A
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein (hSNM1) (hSNM1A).

RBL2_MOUSE
NC score	0.009428 (rank : 1082)	θ value	5.27518 (rank : 702)
Query Neighborhood Hits	808	Target Neighborhood Hits	40	Shared Neighborhood Hits	11
SwissProt Accessions	Q64700	Gene names	Rbl2
Domain Architecture
Description	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (PRB2) (P130) (RBR-2).

CD177_HUMAN
NC score	0.008884 (rank : 1083)	θ value	6.88961 (rank : 722)
Query Neighborhood Hits	808	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N6Q3, Q711Q2, Q8NCV9, Q96QH1, Q9HDA5	Gene names	CD177, NB1, PRV1
Domain Architecture	No domain graphic available
Description	CD177 antigen precursor (Polycythemia rubra vera protein 1) (PRV-1) (NB1 glycoprotein) (NB1 GP) (Human neutrophil alloantigen 2a) (HNA- 2a).

SEPT9_MOUSE
NC score	0.008792 (rank : 1084)	θ value	5.27518 (rank : 704)
Query Neighborhood Hits	808	Target Neighborhood Hits	238	Shared Neighborhood Hits	23
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

C163A_HUMAN
NC score	0.008587 (rank : 1085)	θ value	1.81305 (rank : 584)
Query Neighborhood Hits	808	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

RC3H1_HUMAN
NC score	0.008472 (rank : 1086)	θ value	6.88961 (rank : 752)
Query Neighborhood Hits	808	Target Neighborhood Hits	433	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

CD5_MOUSE
NC score	0.007539 (rank : 1087)	θ value	6.88961 (rank : 723)
Query Neighborhood Hits	808	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	P13379	Gene names	Cd5, Ly-1
Domain Architecture
Description	T-cell surface glycoprotein CD5 precursor (Lymphocyte antigen Ly-1) (Lyt-1).

HSPB1_MOUSE
NC score	0.007367 (rank : 1088)	θ value	3.0926 (rank : 639)
Query Neighborhood Hits	808	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P14602	Gene names	Hspb1, Hsp25, Hsp27
Domain Architecture
Description	Heat-shock protein beta-1 (HspB1) (Heat shock 27 kDa protein) (HSP 27) (Growth-related 25 kDa protein) (P25) (HSP25).

BRD1_HUMAN
NC score	0.007340 (rank : 1089)	θ value	1.06291 (rank : 532)
Query Neighborhood Hits	808	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

NUD12_HUMAN
NC score	0.007301 (rank : 1090)	θ value	1.81305 (rank : 590)
Query Neighborhood Hits	808	Target Neighborhood Hits	222	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

PKHA4_MOUSE
NC score	0.007141 (rank : 1091)	θ value	8.99809 (rank : 795)
Query Neighborhood Hits	808	Target Neighborhood Hits	202	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

SEM6D_MOUSE
NC score	0.007021 (rank : 1092)	θ value	6.88961 (rank : 755)
Query Neighborhood Hits	808	Target Neighborhood Hits	161	Shared Neighborhood Hits	14
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

TMF1_HUMAN
NC score	0.006624 (rank : 1093)	θ value	4.03905 (rank : 678)
Query Neighborhood Hits	808	Target Neighborhood Hits	987	Shared Neighborhood Hits	42
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

RBL2_HUMAN
NC score	0.006574 (rank : 1094)	θ value	8.99809 (rank : 797)
Query Neighborhood Hits	808	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q08999, Q15073, Q16084, Q92812	Gene names	RBL2, RB2
Domain Architecture
Description	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (PRB2) (P130) (RBR-2).

UBR1_HUMAN
NC score	0.006315 (rank : 1095)	θ value	3.0926 (rank : 649)
Query Neighborhood Hits	808	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

AT2A3_HUMAN
NC score	0.005997 (rank : 1096)	θ value	0.813845 (rank : 511)
Query Neighborhood Hits	808	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q93084, O60900, O60901, O75501, O75502, Q16115, Q8TEX5, Q8TEX6	Gene names	ATP2A3
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8) (Calcium pump 3) (SERCA3) (SR Ca(2+)-ATPase 3).

ATF1_HUMAN
NC score	0.005856 (rank : 1097)	θ value	8.99809 (rank : 763)
Query Neighborhood Hits	808	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	P18846, P25168	Gene names	ATF1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TREB36 protein).

MTF2_MOUSE
NC score	0.005516 (rank : 1098)	θ value	8.99809 (rank : 787)
Query Neighborhood Hits	808	Target Neighborhood Hits	126	Shared Neighborhood Hits	12
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

IC1_MOUSE
NC score	0.005319 (rank : 1099)	θ value	4.03905 (rank : 665)
Query Neighborhood Hits	808	Target Neighborhood Hits	164	Shared Neighborhood Hits	14
SwissProt Accessions	P97290, O88330, Q99M43, Q9QX09	Gene names	Serping1, C1nh
Domain Architecture
Description	Plasma protease C1 inhibitor precursor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor).

WWP1_MOUSE
NC score	0.005190 (rank : 1100)	θ value	6.88961 (rank : 760)
Query Neighborhood Hits	808	Target Neighborhood Hits	138	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

MTF2_HUMAN
NC score	0.005079 (rank : 1101)	θ value	8.99809 (rank : 786)
Query Neighborhood Hits	808	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

AT2A3_MOUSE
NC score	0.004961 (rank : 1102)	θ value	0.813845 (rank : 512)
Query Neighborhood Hits	808	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q64518, O70625, Q64517	Gene names	Atp2a3
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (EC 3.6.3.8) (Calcium pump 3) (SERCA3) (SR Ca(2+)-ATPase 3).

JHD3B_HUMAN
NC score	0.004808 (rank : 1103)	θ value	4.03905 (rank : 667)
Query Neighborhood Hits	808	Target Neighborhood Hits	128	Shared Neighborhood Hits	17
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

UBP8_HUMAN
NC score	0.004340 (rank : 1104)	θ value	1.06291 (rank : 557)
Query Neighborhood Hits	808	Target Neighborhood Hits	751	Shared Neighborhood Hits	29
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

ZEP1_HUMAN
NC score	0.004052 (rank : 1105)	θ value	0.0330416 (rank : 345)
Query Neighborhood Hits	808	Target Neighborhood Hits	1036	Shared Neighborhood Hits	46
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

KLH23_HUMAN
NC score	0.003695 (rank : 1106)	θ value	1.81305 (rank : 586)
Query Neighborhood Hits	808	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NBE8, Q8N9B9, Q96FT8	Gene names	KLHL23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

MDM2_MOUSE
NC score	0.003675 (rank : 1107)	θ value	8.99809 (rank : 784)
Query Neighborhood Hits	808	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

AAK1_MOUSE
NC score	0.003625 (rank : 1108)	θ value	2.36792 (rank : 601)
Query Neighborhood Hits	808	Target Neighborhood Hits	1051	Shared Neighborhood Hits	67
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

SO1C1_MOUSE
NC score	0.003348 (rank : 1109)	θ value	8.99809 (rank : 801)
Query Neighborhood Hits	808	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

RET_HUMAN
NC score	0.003343 (rank : 1110)	θ value	1.38821 (rank : 575)
Query Neighborhood Hits	808	Target Neighborhood Hits	873	Shared Neighborhood Hits	40
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

CCNB2_MOUSE
NC score	0.003239 (rank : 1111)	θ value	4.03905 (rank : 657)
Query Neighborhood Hits	808	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P30276	Gene names	Ccnb2, Cycb2
Domain Architecture
Description	G2/mitotic-specific cyclin-B2.

GPVI_HUMAN
NC score	0.003096 (rank : 1112)	θ value	6.88961 (rank : 732)
Query Neighborhood Hits	808	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HCN6, Q9HCN7, Q9UIF2	Gene names	GP6, GPVI
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein VI precursor.

RET_MOUSE
NC score	0.002937 (rank : 1113)	θ value	6.88961 (rank : 753)
Query Neighborhood Hits	808	Target Neighborhood Hits	884	Shared Neighborhood Hits	45
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

KIF17_MOUSE
NC score	0.002796 (rank : 1114)	θ value	0.21417 (rank : 431)
Query Neighborhood Hits	808	Target Neighborhood Hits	452	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

AAK1_HUMAN
NC score	0.002562 (rank : 1115)	θ value	8.99809 (rank : 761)
Query Neighborhood Hits	808	Target Neighborhood Hits	1077	Shared Neighborhood Hits	69
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

KLH23_MOUSE
NC score	0.002410 (rank : 1116)	θ value	2.36792 (rank : 612)
Query Neighborhood Hits	808	Target Neighborhood Hits	188	Shared Neighborhood Hits	11
SwissProt Accessions	Q6GQU2, Q8C840	Gene names	Klhl23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

DTBP1_MOUSE
NC score	0.002095 (rank : 1117)	θ value	8.99809 (rank : 772)
Query Neighborhood Hits	808	Target Neighborhood Hits	209	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

UBP20_HUMAN
NC score	0.001201 (rank : 1118)	θ value	5.27518 (rank : 712)
Query Neighborhood Hits	808	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

CP135_MOUSE
NC score	0.001065 (rank : 1119)	θ value	4.03905 (rank : 658)
Query Neighborhood Hits	808	Target Neighborhood Hits	1278	Shared Neighborhood Hits	46
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

TRAF7_MOUSE
NC score	0.000328 (rank : 1120)	θ value	0.365318 (rank : 475)
Query Neighborhood Hits	808	Target Neighborhood Hits	470	Shared Neighborhood Hits	10
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

ARHGA_HUMAN
NC score	-0.000535 (rank : 1121)	θ value	6.88961 (rank : 718)
Query Neighborhood Hits	808	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

TRAF7_HUMAN
NC score	-0.000901 (rank : 1122)	θ value	8.99809 (rank : 805)
Query Neighborhood Hits	808	Target Neighborhood Hits	482	Shared Neighborhood Hits	13
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

ABCG5_MOUSE
NC score	-0.001091 (rank : 1123)	θ value	5.27518 (rank : 681)
Query Neighborhood Hits	808	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PE8	Gene names	Abcg5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

LHX6_MOUSE
NC score	-0.002050 (rank : 1124)	θ value	0.47712 (rank : 485)
Query Neighborhood Hits	808	Target Neighborhood Hits	399	Shared Neighborhood Hits	6
SwissProt Accessions	O88706	Gene names	Lhx6
Domain Architecture
Description	LIM/homeobox protein Lhx6.

TRIM3_MOUSE
NC score	-0.002200 (rank : 1125)	θ value	4.03905 (rank : 680)
Query Neighborhood Hits	808	Target Neighborhood Hits	351	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

VDR_HUMAN
NC score	-0.003645 (rank : 1126)	θ value	8.99809 (rank : 807)
Query Neighborhood Hits	808	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_MOUSE
NC score	-0.003677 (rank : 1127)	θ value	8.99809 (rank : 808)
Query Neighborhood Hits	808	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

CP270_MOUSE
NC score	-0.004883 (rank : 1128)	θ value	8.99809 (rank : 769)
Query Neighborhood Hits	808	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	Q91W64, Q5GLY9, Q80VW0, Q8R120, Q8VC00	Gene names	Cyp2c70, Cyp2c-70, Cyp2c22
Domain Architecture	No domain graphic available
Description	Cytochrome P450 2C70 (EC 1.14.14.1) (CYPIIC70).

ERN2_HUMAN
NC score	-0.005766 (rank : 1129)	θ value	0.365318 (rank : 466)
Query Neighborhood Hits	808	Target Neighborhood Hits	844	Shared Neighborhood Hits	31
SwissProt Accessions	Q76MJ5, Q6ZNC0	Gene names	ERN2, IRE2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase/endoribonuclease IRE2 precursor (Inositol-requiring protein 2) (hIRE2p) (IRE1b) (Ire1-beta) (Endoplasmic reticulum-to-nucleus signaling 2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)].

KAISO_HUMAN
NC score	-0.008024 (rank : 1130)	θ value	0.62314 (rank : 500)
Query Neighborhood Hits	808	Target Neighborhood Hits	840	Shared Neighborhood Hits	24
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

M4K1_HUMAN
NC score	-0.010427 (rank : 1131)	θ value	8.99809 (rank : 783)
Query Neighborhood Hits	808	Target Neighborhood Hits	884	Shared Neighborhood Hits	32
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

SLK_HUMAN
NC score	-0.010529 (rank : 1132)	θ value	1.38821 (rank : 576)
Query Neighborhood Hits	808	Target Neighborhood Hits	1775	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

ZN274_HUMAN
NC score	-0.013930 (rank : 1133)	θ value	0.365318 (rank : 476)
Query Neighborhood Hits	808	Target Neighborhood Hits	770	Shared Neighborhood Hits	10
SwissProt Accessions	Q96GC6, Q8WY37, Q8WY38, Q92969, Q9UII0, Q9UII1	Gene names	ZNF274
Domain Architecture
Description	Zinc finger protein 274 (Zinc finger protein HFB101) (Zinc finger protein zfp2) (Zf2).

ZN679_HUMAN
NC score	-0.014415 (rank : 1134)	θ value	2.36792 (rank : 631)
Query Neighborhood Hits	808	Target Neighborhood Hits	746	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IYX0	Gene names	ZNF679
Domain Architecture	No domain graphic available
Description	Zinc finger protein 679.

HELI_MOUSE
NC score	-0.014475 (rank : 1135)	θ value	5.27518 (rank : 694)
Query Neighborhood Hits	808	Target Neighborhood Hits	746	Shared Neighborhood Hits	10
SwissProt Accessions	P81183	Gene names	Ikzf2, Helios, Zfpn1a2, Znfn1a2
Domain Architecture	No domain graphic available
Description	Zinc finger protein Helios (IKAROS family zinc finger protein 2).

EGR2_HUMAN
NC score	-0.014882 (rank : 1136)	θ value	8.99809 (rank : 773)
Query Neighborhood Hits	808	Target Neighborhood Hits	728	Shared Neighborhood Hits	15
SwissProt Accessions	P11161, Q8IV26, Q9UNA6	Gene names	EGR2, KROX20
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein) (AT591).

ZN588_HUMAN
NC score	-0.015006 (rank : 1137)	θ value	5.27518 (rank : 715)
Query Neighborhood Hits	808	Target Neighborhood Hits	759	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UII5	Gene names	ZNF588, ZFD25
Domain Architecture	No domain graphic available
Description	Zinc finger protein 588 (Zinc finger protein ZFD25).

OR6N2_HUMAN
NC score	-0.015315 (rank : 1138)	θ value	8.99809 (rank : 789)
Query Neighborhood Hits	808	Target Neighborhood Hits	698	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGY6	Gene names	OR6N2
Domain Architecture
Description	Olfactory receptor 6N2.