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Network neighborhood for query Sequence : LRP11_HUMAN

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LRP11_HUMAN
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LRP11_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP11_MOUSE
θ value	1.1637e-148 (rank : 2)	NC score	0.985268 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	81	Shared Neighborhood Hits	65
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

SPIT1_HUMAN
θ value	9.87957e-23 (rank : 3)	NC score	0.611776 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPIT1_MOUSE
θ value	3.75424e-22 (rank : 4)	NC score	0.589525 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	96	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

K0319_MOUSE
θ value	1.38178e-16 (rank : 5)	NC score	0.453807 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

K0319_HUMAN
θ value	2.20605e-14 (rank : 6)	NC score	0.445614 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

LRP2_HUMAN
θ value	0.000121331 (rank : 7)	NC score	0.349368 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	573	Shared Neighborhood Hits	63
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

SORL_MOUSE
θ value	0.000121331 (rank : 8)	NC score	0.357085 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	439	Shared Neighborhood Hits	63
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LRP8_HUMAN
θ value	0.000270298 (rank : 9)	NC score	0.360963 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	346	Shared Neighborhood Hits	61
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	0.000270298 (rank : 10)	NC score	0.356161 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	385	Shared Neighborhood Hits	61
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

VLDLR_HUMAN
θ value	0.000270298 (rank : 11)	NC score	0.361795 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	383	Shared Neighborhood Hits	63
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	0.000270298 (rank : 12)	NC score	0.360764 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	360	Shared Neighborhood Hits	63
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LDLR_MOUSE
θ value	0.00035302 (rank : 13)	NC score	0.363340 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	382	Shared Neighborhood Hits	64
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1_HUMAN
θ value	0.00035302 (rank : 14)	NC score	0.320329 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	617	Shared Neighborhood Hits	65
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP4_HUMAN
θ value	0.000461057 (rank : 15)	NC score	0.355878 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	355	Shared Neighborhood Hits	63
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	0.000461057 (rank : 16)	NC score	0.354789 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	351	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

SORL_HUMAN
θ value	0.000461057 (rank : 17)	NC score	0.353044 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	440	Shared Neighborhood Hits	64
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

ENTK_HUMAN
θ value	0.00134147 (rank : 18)	NC score	0.161684 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	310	Shared Neighborhood Hits	63
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

LDLR_HUMAN
θ value	0.00175202 (rank : 19)	NC score	0.352665 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	375	Shared Neighborhood Hits	63
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
θ value	0.00228821 (rank : 20)	NC score	0.321975 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	602	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP12_HUMAN
θ value	0.00298849 (rank : 21)	NC score	0.360482 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	205	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP1B_MOUSE
θ value	0.00298849 (rank : 22)	NC score	0.321655 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	606	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP5_HUMAN
θ value	0.00298849 (rank : 23)	NC score	0.382814 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	224	Shared Neighborhood Hits	60
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	0.00390308 (rank : 24)	NC score	0.383946 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	236	Shared Neighborhood Hits	62
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP10_MOUSE
θ value	0.00509761 (rank : 25)	NC score	0.399714 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	169	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_HUMAN
θ value	0.00665767 (rank : 26)	NC score	0.400101 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	197	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_MOUSE
θ value	0.00665767 (rank : 27)	NC score	0.354945 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

TMPS7_HUMAN
θ value	0.00665767 (rank : 28)	NC score	0.202969 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	275	Shared Neighborhood Hits	63
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

LRP6_HUMAN
θ value	0.0113563 (rank : 29)	NC score	0.382399 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	235	Shared Neighborhood Hits	63
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	0.0113563 (rank : 30)	NC score	0.382993 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	232	Shared Neighborhood Hits	63
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

CORIN_HUMAN
θ value	0.0148317 (rank : 31)	NC score	0.226683 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	453	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
θ value	0.0148317 (rank : 32)	NC score	0.223581 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	451	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

SSPO_MOUSE
θ value	0.0148317 (rank : 33)	NC score	0.243706 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	800	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TMPS2_MOUSE
θ value	0.0148317 (rank : 34)	NC score	0.127189 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	243	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

LRP3_HUMAN
θ value	0.0193708 (rank : 35)	NC score	0.387081 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	280	Shared Neighborhood Hits	63
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

MFRP_MOUSE
θ value	0.0193708 (rank : 36)	NC score	0.219099 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

ST14_MOUSE
θ value	0.0193708 (rank : 37)	NC score	0.226695 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	419	Shared Neighborhood Hits	63
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TMPS7_MOUSE
θ value	0.0252991 (rank : 38)	NC score	0.199874 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	275	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

ENTK_MOUSE
θ value	0.0330416 (rank : 39)	NC score	0.161072 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	338	Shared Neighborhood Hits	63
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

NETO2_HUMAN
θ value	0.0330416 (rank : 40)	NC score	0.190779 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	109	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	0.0330416 (rank : 41)	NC score	0.191573 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	113	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

TMPS2_HUMAN
θ value	0.0330416 (rank : 42)	NC score	0.113889 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	252	Shared Neighborhood Hits	49
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

CD320_HUMAN
θ value	0.0563607 (rank : 43)	NC score	0.454864 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	103	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

NETO1_HUMAN
θ value	0.0563607 (rank : 44)	NC score	0.183012 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	110	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	0.0563607 (rank : 45)	NC score	0.182542 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

ST14_HUMAN
θ value	0.0736092 (rank : 46)	NC score	0.226309 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	409	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

TMPS6_MOUSE
θ value	0.0736092 (rank : 47)	NC score	0.170901 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	341	Shared Neighborhood Hits	60
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

CO9_HUMAN
θ value	0.0961366 (rank : 48)	NC score	0.286795 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	147	Shared Neighborhood Hits	59
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

MFRP_HUMAN
θ value	0.125558 (rank : 49)	NC score	0.228871 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CO8A_HUMAN
θ value	0.163984 (rank : 50)	NC score	0.205967 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	200	Shared Neighborhood Hits	57
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

TMPS3_HUMAN
θ value	0.163984 (rank : 51)	NC score	0.110424 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	245	Shared Neighborhood Hits	58
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

SHAN1_HUMAN
θ value	0.21417 (rank : 52)	NC score	0.018360 (rank : 337)
Query Neighborhood Hits	82	Target Neighborhood Hits	1041	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TMPS6_HUMAN
θ value	0.21417 (rank : 53)	NC score	0.174924 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	338	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

CO6_HUMAN
θ value	0.365318 (rank : 54)	NC score	0.198256 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	331	Shared Neighborhood Hits	62
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

PGBM_HUMAN
θ value	0.365318 (rank : 55)	NC score	0.148201 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	1113	Shared Neighborhood Hits	64
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	0.47712 (rank : 56)	NC score	0.158142 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	1073	Shared Neighborhood Hits	67
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SF04_HUMAN
θ value	0.813845 (rank : 57)	NC score	0.034525 (rank : 331)
Query Neighborhood Hits	82	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWZ8, O60378, Q6P3X9, Q8TCQ4, Q8WWT4, Q8WWT5, Q9NTG3	Gene names	SF4
Domain Architecture	No domain graphic available
Description	Splicing factor 4 (RNA-binding protein RBP).

CO9_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.254288 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	153	Shared Neighborhood Hits	58
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CFAI_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.175497 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	289	Shared Neighborhood Hits	62
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

RXFP2_MOUSE
θ value	1.81305 (rank : 60)	NC score	0.073308 (rank : 122)
Query Neighborhood Hits	82	Target Neighborhood Hits	760	Shared Neighborhood Hits	59
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

CO7_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.154279 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	278	Shared Neighborhood Hits	55
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.193548 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	182	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

TMPS3_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.095514 (rank : 86)
Query Neighborhood Hits	82	Target Neighborhood Hits	239	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

ZN205_HUMAN
θ value	3.0926 (rank : 64)	NC score	-0.002168 (rank : 347)
Query Neighborhood Hits	82	Target Neighborhood Hits	743	Shared Neighborhood Hits	3
SwissProt Accessions	O95201	Gene names	ZNF205, ZNF210
Domain Architecture
Description	Zinc finger protein 205 (Zinc finger protein 210).

CJ047_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.025271 (rank : 333)
Query Neighborhood Hits	82	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

MARCS_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.018835 (rank : 336)
Query Neighborhood Hits	82	Target Neighborhood Hits	204	Shared Neighborhood Hits	4
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

TMPS9_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.120933 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	276	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

CFAI_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.161142 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	290	Shared Neighborhood Hits	61
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

PCD16_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.004683 (rank : 342)
Query Neighborhood Hits	82	Target Neighborhood Hits	245	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PER3_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.011837 (rank : 339)
Query Neighborhood Hits	82	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

S39A1_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.020475 (rank : 335)
Query Neighborhood Hits	82	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ03, Q99K44	Gene names	Slc39a1, Zip1, Zirtl
Domain Architecture
Description	Zinc transporter ZIP1 (Zinc-iron-regulated transporter-like) (Solute carrier family 39 member 1).

IDD_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.223227 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	151	Shared Neighborhood Hits	50
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

KCNC4_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.004358 (rank : 343)
Query Neighborhood Hits	82	Target Neighborhood Hits	130	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KLF2_HUMAN
θ value	6.88961 (rank : 74)	NC score	-0.001656 (rank : 346)
Query Neighborhood Hits	82	Target Neighborhood Hits	755	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5W3, Q9UJS5, Q9UKR6	Gene names	KLF2, LKLF
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

KLHL1_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.002578 (rank : 344)
Query Neighborhood Hits	82	Target Neighborhood Hits	193	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI74	Gene names	Klhl1
Domain Architecture
Description	Kelch-like protein 1.

SPEG_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.000308 (rank : 345)
Query Neighborhood Hits	82	Target Neighborhood Hits	1959	Shared Neighborhood Hits	8
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SQSTM_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.015306 (rank : 338)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q64337, Q99JM8	Gene names	Sqstm1, A170, STAP
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Ubiquitin-binding protein p62) (STONE14).

TNR8_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.028476 (rank : 332)
Query Neighborhood Hits	82	Target Neighborhood Hits	208	Shared Neighborhood Hits	11
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

AFF1_MOUSE
θ value	8.99809 (rank : 79)	NC score	0.021860 (rank : 334)
Query Neighborhood Hits	82	Target Neighborhood Hits	351	Shared Neighborhood Hits	6
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

AFF4_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.007266 (rank : 341)
Query Neighborhood Hits	82	Target Neighborhood Hits	581	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

IDD_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.240256 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	127	Shared Neighborhood Hits	53
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

TSKS_MOUSE
θ value	8.99809 (rank : 82)	NC score	0.011246 (rank : 340)
Query Neighborhood Hits	82	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

ACRO_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.065380 (rank : 169)
Query Neighborhood Hits	82	Target Neighborhood Hits	291	Shared Neighborhood Hits	17
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ACRO_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.063949 (rank : 185)
Query Neighborhood Hits	82	Target Neighborhood Hits	185	Shared Neighborhood Hits	17
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

AMBP_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.063012 (rank : 194)
Query Neighborhood Hits	82	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	P02760, P00977, P02759	Gene names	AMBP, HCP, ITIL
Domain Architecture
Description	AMBP protein precursor [Contains: Alpha-1-microglobulin (Protein HC) (Complex-forming glycoprotein heterogeneous in charge) (Alpha-1 microglycoprotein); Inter-alpha-trypsin inhibitor light chain (ITI-LC) (Bikunin) (HI-30)].

AMBP_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.062790 (rank : 197)
Query Neighborhood Hits	82	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q07456, Q61294	Gene names	Ambp, Itil
Domain Architecture
Description	AMBP protein precursor [Contains: Alpha-1-microglobulin; Inter-alpha- trypsin inhibitor light chain (ITI-LC) (Bikunin) (HI-30)].

APOA_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.056934 (rank : 252)
Query Neighborhood Hits	82	Target Neighborhood Hits	221	Shared Neighborhood Hits	17
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

ATRN_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.050819 (rank : 320)
Query Neighborhood Hits	82	Target Neighborhood Hits	525	Shared Neighborhood Hits	30
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

BMP1_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.093806 (rank : 89)
Query Neighborhood Hits	82	Target Neighborhood Hits	233	Shared Neighborhood Hits	35
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.094557 (rank : 87)
Query Neighborhood Hits	82	Target Neighborhood Hits	236	Shared Neighborhood Hits	35
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BSSP4_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.063260 (rank : 192)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

BSSP4_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.062458 (rank : 201)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

C1QR1_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.069136 (rank : 143)
Query Neighborhood Hits	82	Target Neighborhood Hits	493	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.065401 (rank : 168)
Query Neighborhood Hits	82	Target Neighborhood Hits	342	Shared Neighborhood Hits	22
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1RA_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.086870 (rank : 95)
Query Neighborhood Hits	82	Target Neighborhood Hits	379	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.086358 (rank : 96)
Query Neighborhood Hits	82	Target Neighborhood Hits	380	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.087324 (rank : 94)
Query Neighborhood Hits	82	Target Neighborhood Hits	364	Shared Neighborhood Hits	42
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.077166 (rank : 112)
Query Neighborhood Hits	82	Target Neighborhood Hits	359	Shared Neighborhood Hits	42
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CAP7_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.053210 (rank : 287)
Query Neighborhood Hits	82	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	P20160, P80014, Q52LG4	Gene names	AZU1
Domain Architecture
Description	Azurocidin precursor (Cationic antimicrobial protein CAP37) (Heparin- binding protein) (HBP).

CATG_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.051069 (rank : 316)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

CATG_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.051334 (rank : 311)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

CD248_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.080139 (rank : 104)
Query Neighborhood Hits	82	Target Neighborhood Hits	679	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.079688 (rank : 106)
Query Neighborhood Hits	82	Target Neighborhood Hits	578	Shared Neighborhood Hits	24
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CFAD_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.055066 (rank : 264)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

CFAD_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.054849 (rank : 269)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

CLCR_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.061078 (rank : 211)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

CO2_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.050397 (rank : 326)
Query Neighborhood Hits	82	Target Neighborhood Hits	258	Shared Neighborhood Hits	19
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.054231 (rank : 277)
Query Neighborhood Hits	82	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO8B_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.161784 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	199	Shared Neighborhood Hits	60
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.159830 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	224	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CR001_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.151255 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CR001_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.148655 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	67	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

CREL1_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.061570 (rank : 208)
Query Neighborhood Hits	82	Target Neighborhood Hits	441	Shared Neighborhood Hits	19
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.062137 (rank : 204)
Query Neighborhood Hits	82	Target Neighborhood Hits	524	Shared Neighborhood Hits	21
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRUM1_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.053350 (rank : 285)
Query Neighborhood Hits	82	Target Neighborhood Hits	457	Shared Neighborhood Hits	31
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.052657 (rank : 294)
Query Neighborhood Hits	82	Target Neighborhood Hits	444	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CS1A_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.078075 (rank : 108)
Query Neighborhood Hits	82	Target Neighborhood Hits	360	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.080063 (rank : 105)
Query Neighborhood Hits	82	Target Neighborhood Hits	361	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CSMD1_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.050046 (rank : 330)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.052433 (rank : 299)
Query Neighborhood Hits	82	Target Neighborhood Hits	193	Shared Neighborhood Hits	23
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.054571 (rank : 273)
Query Neighborhood Hits	82	Target Neighborhood Hits	188	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CTRB1_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.061493 (rank : 209)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

CTRL_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.061620 (rank : 207)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

CUBN_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.076207 (rank : 115)
Query Neighborhood Hits	82	Target Neighborhood Hits	482	Shared Neighborhood Hits	42
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.084318 (rank : 100)
Query Neighborhood Hits	82	Target Neighborhood Hits	477	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.062552 (rank : 199)
Query Neighborhood Hits	82	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.064130 (rank : 184)
Query Neighborhood Hits	82	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DESC4_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.066972 (rank : 154)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

DLL1_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.057020 (rank : 251)
Query Neighborhood Hits	82	Target Neighborhood Hits	455	Shared Neighborhood Hits	37
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.055095 (rank : 263)
Query Neighborhood Hits	82	Target Neighborhood Hits	456	Shared Neighborhood Hits	32
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DMBT1_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.054527 (rank : 274)
Query Neighborhood Hits	82	Target Neighborhood Hits	152	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.054964 (rank : 267)
Query Neighborhood Hits	82	Target Neighborhood Hits	134	Shared Neighborhood Hits	24
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

EGFB2_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.051505 (rank : 308)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

EGFL7_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.055296 (rank : 259)
Query Neighborhood Hits	82	Target Neighborhood Hits	325	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGF_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.175172 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	343	Shared Neighborhood Hits	24
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.167372 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	358	Shared Neighborhood Hits	25
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELA1_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.057887 (rank : 242)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

ELA2A_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.059766 (rank : 223)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

ELA2A_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.060506 (rank : 216)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

ELA2B_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.059556 (rank : 224)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

ELA3A_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.059062 (rank : 229)
Query Neighborhood Hits	82	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

ELA3B_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.059351 (rank : 226)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

ELNE_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.053590 (rank : 279)
Query Neighborhood Hits	82	Target Neighborhood Hits	164	Shared Neighborhood Hits	17
SwissProt Accessions	P08246, P09649, Q6B0D9, Q6LDP5	Gene names	ELA2
Domain Architecture
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase) (PMN elastase) (Bone marrow serine protease) (Medullasin) (Human leukocyte elastase) (HLE).

ELNE_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.053141 (rank : 288)
Query Neighborhood Hits	82	Target Neighborhood Hits	167	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UP87, Q61515	Gene names	Ela2
Domain Architecture	No domain graphic available
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase).

EPPI_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.068905 (rank : 144)
Query Neighborhood Hits	82	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	O95925, Q86TP9, Q96SD7, Q9HD30	Gene names	SPINLW1, WAP7, WFDC7
Domain Architecture
Description	Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1) (WAP four-disulfide core domain protein 7) (Protease inhibitor WAP7).

EPPI_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.064868 (rank : 175)
Query Neighborhood Hits	82	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DA01	Gene names	Spinlw1
Domain Architecture
Description	Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1).

FA10_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.075762 (rank : 116)
Query Neighborhood Hits	82	Target Neighborhood Hits	431	Shared Neighborhood Hits	38
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.076664 (rank : 114)
Query Neighborhood Hits	82	Target Neighborhood Hits	435	Shared Neighborhood Hits	37
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA11_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.064760 (rank : 178)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA11_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.065102 (rank : 171)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA12_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.065157 (rank : 170)
Query Neighborhood Hits	82	Target Neighborhood Hits	425	Shared Neighborhood Hits	24
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.072812 (rank : 123)
Query Neighborhood Hits	82	Target Neighborhood Hits	404	Shared Neighborhood Hits	36
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.072411 (rank : 126)
Query Neighborhood Hits	82	Target Neighborhood Hits	374	Shared Neighborhood Hits	33
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.077605 (rank : 110)
Query Neighborhood Hits	82	Target Neighborhood Hits	421	Shared Neighborhood Hits	39
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FBLN1_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.070370 (rank : 137)
Query Neighborhood Hits	82	Target Neighborhood Hits	324	Shared Neighborhood Hits	27
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.074239 (rank : 119)
Query Neighborhood Hits	82	Target Neighborhood Hits	329	Shared Neighborhood Hits	27
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.070312 (rank : 138)
Query Neighborhood Hits	82	Target Neighborhood Hits	392	Shared Neighborhood Hits	29
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.072385 (rank : 127)
Query Neighborhood Hits	82	Target Neighborhood Hits	505	Shared Neighborhood Hits	31
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.061770 (rank : 205)
Query Neighborhood Hits	82	Target Neighborhood Hits	293	Shared Neighborhood Hits	25
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.058701 (rank : 233)
Query Neighborhood Hits	82	Target Neighborhood Hits	279	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.062889 (rank : 195)
Query Neighborhood Hits	82	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.062806 (rank : 196)
Query Neighborhood Hits	82	Target Neighborhood Hits	270	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.066585 (rank : 159)
Query Neighborhood Hits	82	Target Neighborhood Hits	329	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.065534 (rank : 167)
Query Neighborhood Hits	82	Target Neighborhood Hits	317	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.070865 (rank : 135)
Query Neighborhood Hits	82	Target Neighborhood Hits	557	Shared Neighborhood Hits	32
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.072590 (rank : 124)
Query Neighborhood Hits	82	Target Neighborhood Hits	563	Shared Neighborhood Hits	37
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.068001 (rank : 147)
Query Neighborhood Hits	82	Target Neighborhood Hits	560	Shared Neighborhood Hits	32
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.067260 (rank : 153)
Query Neighborhood Hits	82	Target Neighborhood Hits	549	Shared Neighborhood Hits	32
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.067850 (rank : 149)
Query Neighborhood Hits	82	Target Neighborhood Hits	543	Shared Neighborhood Hits	30
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.074376 (rank : 118)
Query Neighborhood Hits	82	Target Neighborhood Hits	348	Shared Neighborhood Hits	28
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.075068 (rank : 117)
Query Neighborhood Hits	82	Target Neighborhood Hits	343	Shared Neighborhood Hits	23
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GLU2B_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.132484 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	377	Shared Neighborhood Hits	40
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GLU2B_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.122828 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	357	Shared Neighborhood Hits	40
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GRAH_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.050321 (rank : 327)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

GRAK_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.053421 (rank : 284)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

GRAM_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.059047 (rank : 230)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

GRN_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.096262 (rank : 85)
Query Neighborhood Hits	82	Target Neighborhood Hits	268	Shared Neighborhood Hits	27
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.067437 (rank : 152)
Query Neighborhood Hits	82	Target Neighborhood Hits	248	Shared Neighborhood Hits	22
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HABP2_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.061039 (rank : 212)
Query Neighborhood Hits	82	Target Neighborhood Hits	431	Shared Neighborhood Hits	26
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.064384 (rank : 181)
Query Neighborhood Hits	82	Target Neighborhood Hits	445	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HEPS_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.066469 (rank : 161)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.066450 (rank : 162)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HGFA_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.065552 (rank : 166)
Query Neighborhood Hits	82	Target Neighborhood Hits	436	Shared Neighborhood Hits	28
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.065011 (rank : 173)
Query Neighborhood Hits	82	Target Neighborhood Hits	419	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFL_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.055153 (rank : 260)
Query Neighborhood Hits	82	Target Neighborhood Hits	190	Shared Neighborhood Hits	17
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGFL_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.055100 (rank : 262)
Query Neighborhood Hits	82	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGF_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.051306 (rank : 312)
Query Neighborhood Hits	82	Target Neighborhood Hits	191	Shared Neighborhood Hits	17
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HGF_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.050587 (rank : 323)
Query Neighborhood Hits	82	Target Neighborhood Hits	192	Shared Neighborhood Hits	17
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HPTR_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.057030 (rank : 250)
Query Neighborhood Hits	82	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.057365 (rank : 248)
Query Neighborhood Hits	82	Target Neighborhood Hits	184	Shared Neighborhood Hits	18
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPT_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.059069 (rank : 228)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

JAG1_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.053519 (rank : 282)
Query Neighborhood Hits	82	Target Neighborhood Hits	514	Shared Neighborhood Hits	31
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.054897 (rank : 268)
Query Neighborhood Hits	82	Target Neighborhood Hits	518	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.058122 (rank : 239)
Query Neighborhood Hits	82	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.057852 (rank : 243)
Query Neighborhood Hits	82	Target Neighborhood Hits	504	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

K1B11_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.051660 (rank : 304)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

K1B21_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.051422 (rank : 310)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

K1B22_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.051519 (rank : 307)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

K1B24_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.051099 (rank : 315)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

K1B26_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.051715 (rank : 303)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

K1B27_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.051138 (rank : 314)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

K1KB1_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.052955 (rank : 290)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	19
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

K1KB3_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.051617 (rank : 305)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

K1KB5_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.050768 (rank : 321)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

K1KB8_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.050160 (rank : 328)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

K1KB9_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.052187 (rank : 300)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

KLK10_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.052842 (rank : 292)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK11_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.052822 (rank : 293)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

KLK11_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.051928 (rank : 302)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

KLK12_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.052896 (rank : 291)
Query Neighborhood Hits	82	Target Neighborhood Hits	197	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

KLK13_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.054580 (rank : 272)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KLK14_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.054713 (rank : 270)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK15_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.053573 (rank : 280)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

KLK1_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.050834 (rank : 319)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

KLK2_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.050407 (rank : 325)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

KLK3_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.050055 (rank : 329)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P07288, Q16272, Q86TG8	Gene names	KLK3, APS
Domain Architecture
Description	Prostate-specific antigen precursor (EC 3.4.21.77) (PSA) (Kallikrein- 3) (Semenogelase) (Gamma-seminoprotein) (Seminin) (P-30 antigen).

KLK4_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.054588 (rank : 271)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

KLK5_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.054242 (rank : 276)
Query Neighborhood Hits	82	Target Neighborhood Hits	182	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

KLK6_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.054362 (rank : 275)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK7_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.053347 (rank : 286)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

KLK7_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.053482 (rank : 283)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK9_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.052615 (rank : 296)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

KLKB1_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.064800 (rank : 177)
Query Neighborhood Hits	82	Target Neighborhood Hits	183	Shared Neighborhood Hits	17
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLKB1_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.065563 (rank : 165)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KR106_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.052456 (rank : 298)
Query Neighborhood Hits	82	Target Neighborhood Hits	347	Shared Neighborhood Hits	25
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.057849 (rank : 244)
Query Neighborhood Hits	82	Target Neighborhood Hits	330	Shared Neighborhood Hits	23
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

LCE3B_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.060606 (rank : 215)
Query Neighborhood Hits	82	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LTB1L_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.071896 (rank : 131)
Query Neighborhood Hits	82	Target Neighborhood Hits	553	Shared Neighborhood Hits	34
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.066638 (rank : 158)
Query Neighborhood Hits	82	Target Neighborhood Hits	514	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.071180 (rank : 134)
Query Neighborhood Hits	82	Target Neighborhood Hits	502	Shared Neighborhood Hits	32
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.066522 (rank : 160)
Query Neighborhood Hits	82	Target Neighborhood Hits	479	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.066917 (rank : 156)
Query Neighborhood Hits	82	Target Neighborhood Hits	552	Shared Neighborhood Hits	30
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.059227 (rank : 227)
Query Neighborhood Hits	82	Target Neighborhood Hits	617	Shared Neighborhood Hits	30
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.058260 (rank : 236)
Query Neighborhood Hits	82	Target Neighborhood Hits	502	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.058972 (rank : 231)
Query Neighborhood Hits	82	Target Neighborhood Hits	475	Shared Neighborhood Hits	29
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.062159 (rank : 203)
Query Neighborhood Hits	82	Target Neighborhood Hits	607	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MASP1_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.089111 (rank : 93)
Query Neighborhood Hits	82	Target Neighborhood Hits	369	Shared Neighborhood Hits	42
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.086274 (rank : 97)
Query Neighborhood Hits	82	Target Neighborhood Hits	364	Shared Neighborhood Hits	41
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.085977 (rank : 98)
Query Neighborhood Hits	82	Target Neighborhood Hits	364	Shared Neighborhood Hits	42
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.085452 (rank : 99)
Query Neighborhood Hits	82	Target Neighborhood Hits	382	Shared Neighborhood Hits	41
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MATN2_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.065034 (rank : 172)
Query Neighborhood Hits	82	Target Neighborhood Hits	365	Shared Neighborhood Hits	25
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.057777 (rank : 246)
Query Neighborhood Hits	82	Target Neighborhood Hits	356	Shared Neighborhood Hits	23
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.058869 (rank : 232)
Query Neighborhood Hits	82	Target Neighborhood Hits	268	Shared Neighborhood Hits	18
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.057798 (rank : 245)
Query Neighborhood Hits	82	Target Neighborhood Hits	261	Shared Neighborhood Hits	18
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.060973 (rank : 213)
Query Neighborhood Hits	82	Target Neighborhood Hits	287	Shared Neighborhood Hits	22
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.061241 (rank : 210)
Query Neighborhood Hits	82	Target Neighborhood Hits	277	Shared Neighborhood Hits	24
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCPT1_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.051560 (rank : 306)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

MCPT2_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.050962 (rank : 317)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

MCPT4_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.050712 (rank : 322)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

MCPT6_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.061692 (rank : 206)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

MEGF6_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.062708 (rank : 198)
Query Neighborhood Hits	82	Target Neighborhood Hits	671	Shared Neighborhood Hits	32
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NELL1_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.055065 (rank : 265)
Query Neighborhood Hits	82	Target Neighborhood Hits	451	Shared Neighborhood Hits	25
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.057977 (rank : 240)
Query Neighborhood Hits	82	Target Neighborhood Hits	449	Shared Neighborhood Hits	28
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.056693 (rank : 253)
Query Neighborhood Hits	82	Target Neighborhood Hits	436	Shared Neighborhood Hits	26
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NETR_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.058340 (rank : 234)
Query Neighborhood Hits	82	Target Neighborhood Hits	218	Shared Neighborhood Hits	17
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

NETR_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.059421 (rank : 225)
Query Neighborhood Hits	82	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

NID1_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.140610 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	329	Shared Neighborhood Hits	23
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.142056 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	335	Shared Neighborhood Hits	24
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.131609 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	456	Shared Neighborhood Hits	23
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.133725 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	338	Shared Neighborhood Hits	24
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC1_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.050465 (rank : 324)
Query Neighborhood Hits	82	Target Neighborhood Hits	906	Shared Neighborhood Hits	34
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.055130 (rank : 261)
Query Neighborhood Hits	82	Target Neighborhood Hits	916	Shared Neighborhood Hits	38
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.051186 (rank : 313)
Query Neighborhood Hits	82	Target Neighborhood Hits	1113	Shared Neighborhood Hits	39
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.051423 (rank : 309)
Query Neighborhood Hits	82	Target Neighborhood Hits	1069	Shared Neighborhood Hits	41
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.050952 (rank : 318)
Query Neighborhood Hits	82	Target Neighborhood Hits	905	Shared Neighborhood Hits	38
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NRP1_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.055433 (rank : 256)
Query Neighborhood Hits	82	Target Neighborhood Hits	119	Shared Neighborhood Hits	18
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.052634 (rank : 295)
Query Neighborhood Hits	82	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.058232 (rank : 237)
Query Neighborhood Hits	82	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.057898 (rank : 241)
Query Neighborhood Hits	82	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRPN_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.053544 (rank : 281)
Query Neighborhood Hits	82	Target Neighborhood Hits	182	Shared Neighborhood Hits	17
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

NRPN_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.051982 (rank : 301)
Query Neighborhood Hits	82	Target Neighborhood Hits	186	Shared Neighborhood Hits	18
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

PCOC1_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.068799 (rank : 145)
Query Neighborhood Hits	82	Target Neighborhood Hits	146	Shared Neighborhood Hits	18
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.068078 (rank : 146)
Query Neighborhood Hits	82	Target Neighborhood Hits	100	Shared Neighborhood Hits	18
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.070813 (rank : 136)
Query Neighborhood Hits	82	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.072030 (rank : 129)
Query Neighborhood Hits	82	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.052558 (rank : 297)
Query Neighborhood Hits	82	Target Neighborhood Hits	74	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.056021 (rank : 255)
Query Neighborhood Hits	82	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PHXR5_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.053002 (rank : 289)
Query Neighborhood Hits	82	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PLMN_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.057394 (rank : 247)
Query Neighborhood Hits	82	Target Neighborhood Hits	204	Shared Neighborhood Hits	17
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PLMN_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.058157 (rank : 238)
Query Neighborhood Hits	82	Target Neighborhood Hits	208	Shared Neighborhood Hits	19
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

POLS2_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.066028 (rank : 163)
Query Neighborhood Hits	82	Target Neighborhood Hits	192	Shared Neighborhood Hits	18
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

POLS2_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.064856 (rank : 176)
Query Neighborhood Hits	82	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

PROC_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.077727 (rank : 109)
Query Neighborhood Hits	82	Target Neighborhood Hits	406	Shared Neighborhood Hits	35
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.081519 (rank : 102)
Query Neighborhood Hits	82	Target Neighborhood Hits	426	Shared Neighborhood Hits	36
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROS_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.072559 (rank : 125)
Query Neighborhood Hits	82	Target Neighborhood Hits	340	Shared Neighborhood Hits	27
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.069866 (rank : 141)
Query Neighborhood Hits	82	Target Neighborhood Hits	330	Shared Neighborhood Hits	23
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.080514 (rank : 103)
Query Neighborhood Hits	82	Target Neighborhood Hits	422	Shared Neighborhood Hits	37
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.069976 (rank : 140)
Query Neighborhood Hits	82	Target Neighborhood Hits	410	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PRS27_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.064271 (rank : 182)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRS27_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.064690 (rank : 179)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

PRSS8_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.063162 (rank : 193)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRSS8_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.064219 (rank : 183)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

RXFP2_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.071983 (rank : 130)
Query Neighborhood Hits	82	Target Neighborhood Hits	736	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

SCUB3_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.093680 (rank : 90)
Query Neighborhood Hits	82	Target Neighborhood Hits	428	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.093279 (rank : 92)
Query Neighborhood Hits	82	Target Neighborhood Hits	442	Shared Neighborhood Hits	40
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SPIT2_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.116369 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	O43291, O00271, O14895, Q5TZQ3, Q969E0	Gene names	SPINT2, HAI2, KOP
Domain Architecture
Description	Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin).

SPIT2_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.100568 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WU03, Q9WU04, Q9WU05	Gene names	Spint2, Hai2
Domain Architecture
Description	Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth factor activator inhibitor type 2) (HAI-2).

SPIT3_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.083429 (rank : 101)
Query Neighborhood Hits	82	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P49223, Q6UDR8, Q96KK2	Gene names	SPINT3
Domain Architecture	No domain graphic available
Description	Kunitz-type protease inhibitor 3 precursor (HKIB9).

TENA_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.071291 (rank : 132)
Query Neighborhood Hits	82	Target Neighborhood Hits	631	Shared Neighborhood Hits	35
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.070054 (rank : 139)
Query Neighborhood Hits	82	Target Neighborhood Hits	596	Shared Neighborhood Hits	39
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENX_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.053739 (rank : 278)
Query Neighborhood Hits	82	Target Neighborhood Hits	789	Shared Neighborhood Hits	33
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TEST_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.066926 (rank : 155)
Query Neighborhood Hits	82	Target Neighborhood Hits	172	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

TEST_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.064873 (rank : 174)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

TFPI1_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.098149 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P10646, O95103	Gene names	TFPI, LACI, TFPI1
Domain Architecture
Description	Tissue factor pathway inhibitor precursor (TFPI) (Lipoprotein- associated coagulation inhibitor) (LACI) (Extrinsic pathway inhibitor) (EPI).

TFPI1_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.098977 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	O54819, Q9Z2U8	Gene names	Tfpi
Domain Architecture
Description	Tissue factor pathway inhibitor precursor (TFPI) (Lipoprotein- associated coagulation inhibitor) (LACI) (Extrinsic pathway inhibitor) (EPI).

TFPI2_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.109220 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P48307	Gene names	TFPI2
Domain Architecture
Description	Tissue factor pathway inhibitor 2 precursor (TFPI-2) (Placental protein 5) (PP5).

TFPI2_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.107110 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	O35536	Gene names	Tfpi2
Domain Architecture
Description	Tissue factor pathway inhibitor 2 precursor (TFPI-2).

THRB_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.058264 (rank : 235)
Query Neighborhood Hits	82	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.057156 (rank : 249)
Query Neighborhood Hits	82	Target Neighborhood Hits	195	Shared Neighborhood Hits	17
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TLL1_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.096573 (rank : 84)
Query Neighborhood Hits	82	Target Neighborhood Hits	236	Shared Neighborhood Hits	35
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.097061 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	237	Shared Neighborhood Hits	35
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.093295 (rank : 91)
Query Neighborhood Hits	82	Target Neighborhood Hits	241	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.094088 (rank : 88)
Query Neighborhood Hits	82	Target Neighborhood Hits	240	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TM11D_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.065639 (rank : 164)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11D_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.066861 (rank : 157)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.069138 (rank : 142)
Query Neighborhood Hits	82	Target Neighborhood Hits	181	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TM11E_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.067769 (rank : 150)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS4_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.079456 (rank : 107)
Query Neighborhood Hits	82	Target Neighborhood Hits	203	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS4_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.077349 (rank : 111)
Query Neighborhood Hits	82	Target Neighborhood Hits	210	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS5_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.067885 (rank : 148)
Query Neighborhood Hits	82	Target Neighborhood Hits	181	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS5_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.067622 (rank : 151)
Query Neighborhood Hits	82	Target Neighborhood Hits	185	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS9_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.110394 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	296	Shared Neighborhood Hits	55
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TMPSD_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.074188 (rank : 120)
Query Neighborhood Hits	82	Target Neighborhood Hits	333	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.072199 (rank : 128)
Query Neighborhood Hits	82	Target Neighborhood Hits	334	Shared Neighborhood Hits	25
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMSP8_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.063810 (rank : 187)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TPA_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.062539 (rank : 200)
Query Neighborhood Hits	82	Target Neighborhood Hits	324	Shared Neighborhood Hits	24
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.062451 (rank : 202)
Query Neighborhood Hits	82	Target Neighborhood Hits	335	Shared Neighborhood Hits	25
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRBM_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.071215 (rank : 133)
Query Neighborhood Hits	82	Target Neighborhood Hits	339	Shared Neighborhood Hits	26
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.073862 (rank : 121)
Query Neighborhood Hits	82	Target Neighborhood Hits	361	Shared Neighborhood Hits	27
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRY1_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.055356 (rank : 258)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

TRY2_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.055391 (rank : 257)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

TRY2_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.056029 (rank : 254)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

TRY3_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.055014 (rank : 266)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

TRYA1_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.060272 (rank : 220)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

TRYB1_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.060462 (rank : 217)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB1_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.060392 (rank : 219)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYB2_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.060462 (rank : 218)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRYD_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.059813 (rank : 222)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TRYG1_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.063261 (rank : 191)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TRYG1_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.063514 (rank : 189)
Query Neighborhood Hits	82	Target Neighborhood Hits	181	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TSG6_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.063836 (rank : 186)
Query Neighborhood Hits	82	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.064397 (rank : 180)
Query Neighborhood Hits	82	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSP50_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.063797 (rank : 188)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

UROK_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.060059 (rank : 221)
Query Neighborhood Hits	82	Target Neighborhood Hits	272	Shared Neighborhood Hits	24
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROK_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.060711 (rank : 214)
Query Neighborhood Hits	82	Target Neighborhood Hits	273	Shared Neighborhood Hits	23
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

WFDC8_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.063442 (rank : 190)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

ZAN_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.076965 (rank : 113)
Query Neighborhood Hits	82	Target Neighborhood Hits	808	Shared Neighborhood Hits	35
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

LRP11_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP11_MOUSE
NC score	0.985268 (rank : 2)	θ value	1.1637e-148 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	81	Shared Neighborhood Hits	65
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

SPIT1_HUMAN
NC score	0.611776 (rank : 3)	θ value	9.87957e-23 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPIT1_MOUSE
NC score	0.589525 (rank : 4)	θ value	3.75424e-22 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	96	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

CD320_HUMAN
NC score	0.454864 (rank : 5)	θ value	0.0563607 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	103	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

K0319_MOUSE
NC score	0.453807 (rank : 6)	θ value	1.38178e-16 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

K0319_HUMAN
NC score	0.445614 (rank : 7)	θ value	2.20605e-14 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

LRP10_HUMAN
NC score	0.400101 (rank : 8)	θ value	0.00665767 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	197	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
NC score	0.399714 (rank : 9)	θ value	0.00509761 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	169	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP3_HUMAN
NC score	0.387081 (rank : 10)	θ value	0.0193708 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	280	Shared Neighborhood Hits	63
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP5_MOUSE
NC score	0.383946 (rank : 11)	θ value	0.00390308 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	236	Shared Neighborhood Hits	62
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_MOUSE
NC score	0.382993 (rank : 12)	θ value	0.0113563 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	232	Shared Neighborhood Hits	63
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP5_HUMAN
NC score	0.382814 (rank : 13)	θ value	0.00298849 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	224	Shared Neighborhood Hits	60
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP6_HUMAN
NC score	0.382399 (rank : 14)	θ value	0.0113563 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	235	Shared Neighborhood Hits	63
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LDLR_MOUSE
NC score	0.363340 (rank : 15)	θ value	0.00035302 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	382	Shared Neighborhood Hits	64
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

VLDLR_HUMAN
NC score	0.361795 (rank : 16)	θ value	0.000270298 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	383	Shared Neighborhood Hits	63
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LRP8_HUMAN
NC score	0.360963 (rank : 17)	θ value	0.000270298 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	346	Shared Neighborhood Hits	61
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

VLDLR_MOUSE
NC score	0.360764 (rank : 18)	θ value	0.000270298 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	360	Shared Neighborhood Hits	63
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LRP12_HUMAN
NC score	0.360482 (rank : 19)	θ value	0.00298849 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	205	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

SORL_MOUSE
NC score	0.357085 (rank : 20)	θ value	0.000121331 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	439	Shared Neighborhood Hits	63
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LRP8_MOUSE
NC score	0.356161 (rank : 21)	θ value	0.000270298 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	385	Shared Neighborhood Hits	61
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP4_HUMAN
NC score	0.355878 (rank : 22)	θ value	0.000461057 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	355	Shared Neighborhood Hits	63
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP12_MOUSE
NC score	0.354945 (rank : 23)	θ value	0.00665767 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP4_MOUSE
NC score	0.354789 (rank : 24)	θ value	0.000461057 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	351	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

SORL_HUMAN
NC score	0.353044 (rank : 25)	θ value	0.000461057 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	440	Shared Neighborhood Hits	64
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

LDLR_HUMAN
NC score	0.352665 (rank : 26)	θ value	0.00175202 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	375	Shared Neighborhood Hits	63
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP2_HUMAN
NC score	0.349368 (rank : 27)	θ value	0.000121331 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	573	Shared Neighborhood Hits	63
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP1B_HUMAN
NC score	0.321975 (rank : 28)	θ value	0.00228821 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	602	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
NC score	0.321655 (rank : 29)	θ value	0.00298849 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	606	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
NC score	0.320329 (rank : 30)	θ value	0.00035302 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	617	Shared Neighborhood Hits	65
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

CO9_HUMAN
NC score	0.286795 (rank : 31)	θ value	0.0961366 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	147	Shared Neighborhood Hits	59
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
NC score	0.254288 (rank : 32)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	153	Shared Neighborhood Hits	58
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

SSPO_MOUSE
NC score	0.243706 (rank : 33)	θ value	0.0148317 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	800	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

IDD_HUMAN
NC score	0.240256 (rank : 34)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	127	Shared Neighborhood Hits	53
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

MFRP_HUMAN
NC score	0.228871 (rank : 35)	θ value	0.125558 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

ST14_MOUSE
NC score	0.226695 (rank : 36)	θ value	0.0193708 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	419	Shared Neighborhood Hits	63
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

CORIN_HUMAN
NC score	0.226683 (rank : 37)	θ value	0.0148317 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	453	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

ST14_HUMAN
NC score	0.226309 (rank : 38)	θ value	0.0736092 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	409	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

CORIN_MOUSE
NC score	0.223581 (rank : 39)	θ value	0.0148317 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	451	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

IDD_MOUSE
NC score	0.223227 (rank : 40)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	151	Shared Neighborhood Hits	50
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

MFRP_MOUSE
NC score	0.219099 (rank : 41)	θ value	0.0193708 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CO8A_HUMAN
NC score	0.205967 (rank : 42)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	200	Shared Neighborhood Hits	57
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

TMPS7_HUMAN
NC score	0.202969 (rank : 43)	θ value	0.00665767 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	275	Shared Neighborhood Hits	63
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
NC score	0.199874 (rank : 44)	θ value	0.0252991 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	275	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

CO6_HUMAN
NC score	0.198256 (rank : 45)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	331	Shared Neighborhood Hits	62
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO8A_MOUSE
NC score	0.193548 (rank : 46)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	182	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

NETO2_MOUSE
NC score	0.191573 (rank : 47)	θ value	0.0330416 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	113	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_HUMAN
NC score	0.190779 (rank : 48)	θ value	0.0330416 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	109	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO1_HUMAN
NC score	0.183012 (rank : 49)	θ value	0.0563607 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	110	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
NC score	0.182542 (rank : 50)	θ value	0.0563607 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

CFAI_HUMAN
NC score	0.175497 (rank : 51)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	289	Shared Neighborhood Hits	62
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

EGF_HUMAN
NC score	0.175172 (rank : 52)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	82	Target Neighborhood Hits	343	Shared Neighborhood Hits	24
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

TMPS6_HUMAN
NC score	0.174924 (rank : 53)	θ value	0.21417 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	338	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
NC score	0.170901 (rank : 54)	θ value	0.0736092 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	341	Shared Neighborhood Hits	60
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

EGF_MOUSE
NC score	0.167372 (rank : 55)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	82	Target Neighborhood Hits	358	Shared Neighborhood Hits	25
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

CO8B_HUMAN
NC score	0.161784 (rank : 56)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	82	Target Neighborhood Hits	199	Shared Neighborhood Hits	60
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ENTK_HUMAN
NC score	0.161684 (rank : 57)	θ value	0.00134147 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	310	Shared Neighborhood Hits	63
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

CFAI_MOUSE
NC score	0.161142 (rank : 58)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	290	Shared Neighborhood Hits	61
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

ENTK_MOUSE
NC score	0.161072 (rank : 59)	θ value	0.0330416 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	338	Shared Neighborhood Hits	63
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

CO8B_MOUSE
NC score	0.159830 (rank : 60)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	82	Target Neighborhood Hits	224	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

PGBM_MOUSE
NC score	0.158142 (rank : 61)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	1073	Shared Neighborhood Hits	67
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

CO7_HUMAN
NC score	0.154279 (rank : 62)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	278	Shared Neighborhood Hits	55
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CR001_HUMAN
NC score	0.151255 (rank : 63)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	82	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CR001_MOUSE
NC score	0.148655 (rank : 64)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	82	Target Neighborhood Hits	67	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

PGBM_HUMAN
NC score	0.148201 (rank : 65)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	1113	Shared Neighborhood Hits	64
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NID1_MOUSE
NC score	0.142056 (rank : 66)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	82	Target Neighborhood Hits	335	Shared Neighborhood Hits	24
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_HUMAN
NC score	0.140610 (rank : 67)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	82	Target Neighborhood Hits	329	Shared Neighborhood Hits	23
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_MOUSE
NC score	0.133725 (rank : 68)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	82	Target Neighborhood Hits	338	Shared Neighborhood Hits	24
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

GLU2B_HUMAN
NC score	0.132484 (rank : 69)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	82	Target Neighborhood Hits	377	Shared Neighborhood Hits	40
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

NID2_HUMAN
NC score	0.131609 (rank : 70)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	82	Target Neighborhood Hits	456	Shared Neighborhood Hits	23
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

TMPS2_MOUSE
NC score	0.127189 (rank : 71)	θ value	0.0148317 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	243	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

GLU2B_MOUSE
NC score	0.122828 (rank : 72)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	82	Target Neighborhood Hits	357	Shared Neighborhood Hits	40
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

TMPS9_HUMAN
NC score	0.120933 (rank : 73)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	276	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

SPIT2_HUMAN
NC score	0.116369 (rank : 74)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	82	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	O43291, O00271, O14895, Q5TZQ3, Q969E0	Gene names	SPINT2, HAI2, KOP
Domain Architecture
Description	Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin).

TMPS2_HUMAN
NC score	0.113889 (rank : 75)	θ value	0.0330416 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	252	Shared Neighborhood Hits	49
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_HUMAN
NC score	0.110424 (rank : 76)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	245	Shared Neighborhood Hits	58
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS9_MOUSE
NC score	0.110394 (rank : 77)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	82	Target Neighborhood Hits	296	Shared Neighborhood Hits	55
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TFPI2_HUMAN
NC score	0.109220 (rank : 78)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	82	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P48307	Gene names	TFPI2
Domain Architecture
Description	Tissue factor pathway inhibitor 2 precursor (TFPI-2) (Placental protein 5) (PP5).

TFPI2_MOUSE
NC score	0.107110 (rank : 79)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	82	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	O35536	Gene names	Tfpi2
Domain Architecture
Description	Tissue factor pathway inhibitor 2 precursor (TFPI-2).

SPIT2_MOUSE
NC score	0.100568 (rank : 80)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	82	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WU03, Q9WU04, Q9WU05	Gene names	Spint2, Hai2
Domain Architecture
Description	Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth factor activator inhibitor type 2) (HAI-2).

TFPI1_MOUSE
NC score	0.098977 (rank : 81)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	82	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	O54819, Q9Z2U8	Gene names	Tfpi
Domain Architecture
Description	Tissue factor pathway inhibitor precursor (TFPI) (Lipoprotein- associated coagulation inhibitor) (LACI) (Extrinsic pathway inhibitor) (EPI).

TFPI1_HUMAN
NC score	0.098149 (rank : 82)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	82	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P10646, O95103	Gene names	TFPI, LACI, TFPI1
Domain Architecture
Description	Tissue factor pathway inhibitor precursor (TFPI) (Lipoprotein- associated coagulation inhibitor) (LACI) (Extrinsic pathway inhibitor) (EPI).

TLL1_MOUSE
NC score	0.097061 (rank : 83)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	82	Target Neighborhood Hits	237	Shared Neighborhood Hits	35
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL1_HUMAN
NC score	0.096573 (rank : 84)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	82	Target Neighborhood Hits	236	Shared Neighborhood Hits	35
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

GRN_HUMAN
NC score	0.096262 (rank : 85)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	82	Target Neighborhood Hits	268	Shared Neighborhood Hits	27
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

TMPS3_MOUSE
NC score	0.095514 (rank : 86)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	239	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

BMP1_MOUSE
NC score	0.094557 (rank : 87)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	82	Target Neighborhood Hits	236	Shared Neighborhood Hits	35
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL2_MOUSE
NC score	0.094088 (rank : 88)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	82	Target Neighborhood Hits	240	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

BMP1_HUMAN
NC score	0.093806 (rank : 89)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	82	Target Neighborhood Hits	233	Shared Neighborhood Hits	35
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

SCUB3_HUMAN
NC score	0.093680 (rank : 90)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	82	Target Neighborhood Hits	428	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TLL2_HUMAN
NC score	0.093295 (rank : 91)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	82	Target Neighborhood Hits	241	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

SCUB3_MOUSE
NC score	0.093279 (rank : 92)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	82	Target Neighborhood Hits	442	Shared Neighborhood Hits	40
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

MASP1_HUMAN
NC score	0.089111 (rank : 93)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	82	Target Neighborhood Hits	369	Shared Neighborhood Hits	42
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

C1R_HUMAN
NC score	0.087324 (rank : 94)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	82	Target Neighborhood Hits	364	Shared Neighborhood Hits	42
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1RA_MOUSE
NC score	0.086870 (rank : 95)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	82	Target Neighborhood Hits	379	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
NC score	0.086358 (rank : 96)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	82	Target Neighborhood Hits	380	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

MASP1_MOUSE
NC score	0.086274 (rank : 97)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	82	Target Neighborhood Hits	364	Shared Neighborhood Hits	41
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
NC score	0.085977 (rank : 98)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	82	Target Neighborhood Hits	364	Shared Neighborhood Hits	42
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
NC score	0.085452 (rank : 99)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	82	Target Neighborhood Hits	382	Shared Neighborhood Hits	41
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CUBN_MOUSE
NC score	0.084318 (rank : 100)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	82	Target Neighborhood Hits	477	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

SPIT3_HUMAN
NC score	0.083429 (rank : 101)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	82	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P49223, Q6UDR8, Q96KK2	Gene names	SPINT3
Domain Architecture	No domain graphic available
Description	Kunitz-type protease inhibitor 3 precursor (HKIB9).

PROC_MOUSE
NC score	0.081519 (rank : 102)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	82	Target Neighborhood Hits	426	Shared Neighborhood Hits	36
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROZ_HUMAN
NC score	0.080514 (rank : 103)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	82	Target Neighborhood Hits	422	Shared Neighborhood Hits	37
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

CD248_HUMAN
NC score	0.080139 (rank : 104)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	82	Target Neighborhood Hits	679	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CS1B_MOUSE
NC score	0.080063 (rank : 105)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	82	Target Neighborhood Hits	361	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CD248_MOUSE
NC score	0.079688 (rank : 106)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	82	Target Neighborhood Hits	578	Shared Neighborhood Hits	24
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TMPS4_HUMAN
NC score	0.079456 (rank : 107)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	82	Target Neighborhood Hits	203	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

CS1A_MOUSE
NC score	0.078075 (rank : 108)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	82	Target Neighborhood Hits	360	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

PROC_HUMAN
NC score	0.077727 (rank : 109)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	82	Target Neighborhood Hits	406	Shared Neighborhood Hits	35
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

FA9_HUMAN
NC score	0.077605 (rank : 110)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	82	Target Neighborhood Hits	421	Shared Neighborhood Hits	39
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

TMPS4_MOUSE
NC score	0.077349 (rank : 111)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	82	Target Neighborhood Hits	210	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

C1S_HUMAN
NC score	0.077166 (rank : 112)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	82	Target Neighborhood Hits	359	Shared Neighborhood Hits	42
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

ZAN_MOUSE
NC score	0.076965 (rank : 113)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	82	Target Neighborhood Hits	808	Shared Neighborhood Hits	35
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

FA10_MOUSE
NC score	0.076664 (rank : 114)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	82	Target Neighborhood Hits	435	Shared Neighborhood Hits	37
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

CUBN_HUMAN
NC score	0.076207 (rank : 115)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	82	Target Neighborhood Hits	482	Shared Neighborhood Hits	42
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

FA10_HUMAN
NC score	0.075762 (rank : 116)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	82	Target Neighborhood Hits	431	Shared Neighborhood Hits	38
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

GAS6_MOUSE
NC score	0.075068 (rank : 117)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	82	Target Neighborhood Hits	343	Shared Neighborhood Hits	23
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_HUMAN
NC score	0.074376 (rank : 118)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	82	Target Neighborhood Hits	348	Shared Neighborhood Hits	28
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBLN1_MOUSE
NC score	0.074239 (rank : 119)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	82	Target Neighborhood Hits	329	Shared Neighborhood Hits	27
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

TMPSD_HUMAN
NC score	0.074188 (rank : 120)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	82	Target Neighborhood Hits	333	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TRBM_MOUSE
NC score	0.073862 (rank : 121)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	82	Target Neighborhood Hits	361	Shared Neighborhood Hits	27
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

RXFP2_MOUSE
NC score	0.073308 (rank : 122)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	760	Shared Neighborhood Hits	59
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

FA7_HUMAN
NC score	0.072812 (rank : 123)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	82	Target Neighborhood Hits	404	Shared Neighborhood Hits	36
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FBN1_MOUSE
NC score	0.072590 (rank : 124)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	82	Target Neighborhood Hits	563	Shared Neighborhood Hits	37
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

PROS_HUMAN
NC score	0.072559 (rank : 125)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	82	Target Neighborhood Hits	340	Shared Neighborhood Hits	27
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

FA7_MOUSE
NC score	0.072411 (rank : 126)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	82	Target Neighborhood Hits	374	Shared Neighborhood Hits	33
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FBLN2_MOUSE
NC score	0.072385 (rank : 127)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	82	Target Neighborhood Hits	505	Shared Neighborhood Hits	31
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

TMPSD_MOUSE
NC score	0.072199 (rank : 128)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	82	Target Neighborhood Hits	334	Shared Neighborhood Hits	25
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

PCOC2_MOUSE
NC score	0.072030 (rank : 129)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	82	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

RXFP2_HUMAN
NC score	0.071983 (rank : 130)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	82	Target Neighborhood Hits	736	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

LTB1L_HUMAN
NC score	0.071896 (rank : 131)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	82	Target Neighborhood Hits	553	Shared Neighborhood Hits	34
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TENA_HUMAN
NC score	0.071291 (rank : 132)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	82	Target Neighborhood Hits	631	Shared Neighborhood Hits	35
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TRBM_HUMAN
NC score	0.071215 (rank : 133)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	82	Target Neighborhood Hits	339	Shared Neighborhood Hits	26
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LTB1S_HUMAN
NC score	0.071180 (rank : 134)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	82	Target Neighborhood Hits	502	Shared Neighborhood Hits	32
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBN1_HUMAN
NC score	0.070865 (rank : 135)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	82	Target Neighborhood Hits	557	Shared Neighborhood Hits	32
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

PCOC2_HUMAN
NC score	0.070813 (rank : 136)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	82	Target Neighborhood Hits	73	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

FBLN1_HUMAN
NC score	0.070370 (rank : 137)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	82	Target Neighborhood Hits	324	Shared Neighborhood Hits	27
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN2_HUMAN
NC score	0.070312 (rank : 138)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	82	Target Neighborhood Hits	392	Shared Neighborhood Hits	29
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

TENA_MOUSE
NC score	0.070054 (rank : 139)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	82	Target Neighborhood Hits	596	Shared Neighborhood Hits	39
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

PROZ_MOUSE
NC score	0.069976 (rank : 140)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	82	Target Neighborhood Hits	410	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROS_MOUSE
NC score	0.069866 (rank : 141)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	82	Target Neighborhood Hits	330	Shared Neighborhood Hits	23
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

TM11E_HUMAN
NC score	0.069138 (rank : 142)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	82	Target Neighborhood Hits	181	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

C1QR1_HUMAN
NC score	0.069136 (rank : 143)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	82	Target Neighborhood Hits	493	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

EPPI_HUMAN
NC score	0.068905 (rank : 144)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	82	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	O95925, Q86TP9, Q96SD7, Q9HD30	Gene names	SPINLW1, WAP7, WFDC7
Domain Architecture
Description	Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1) (WAP four-disulfide core domain protein 7) (Protease inhibitor WAP7).

PCOC1_HUMAN
NC score	0.068799 (rank : 145)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	82	Target Neighborhood Hits	146	Shared Neighborhood Hits	18
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
NC score	0.068078 (rank : 146)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	82	Target Neighborhood Hits	100	Shared Neighborhood Hits	18
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

FBN2_HUMAN
NC score	0.068001 (rank : 147)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	82	Target Neighborhood Hits	560	Shared Neighborhood Hits	32
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

TMPS5_HUMAN
NC score	0.067885 (rank : 148)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	82	Target Neighborhood Hits	181	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

FBN3_HUMAN
NC score	0.067850 (rank : 149)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	82	Target Neighborhood Hits	543	Shared Neighborhood Hits	30
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

TM11E_MOUSE
NC score	0.067769 (rank : 150)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS5_MOUSE
NC score	0.067622 (rank : 151)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	82	Target Neighborhood Hits	185	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

GRN_MOUSE
NC score	0.067437 (rank : 152)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	82	Target Neighborhood Hits	248	Shared Neighborhood Hits	22
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

FBN2_MOUSE
NC score	0.067260 (rank : 153)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	82	Target Neighborhood Hits	549	Shared Neighborhood Hits	32
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

DESC4_MOUSE
NC score	0.066972 (rank : 154)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

TEST_HUMAN
NC score	0.066926 (rank : 155)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	82	Target Neighborhood Hits	172	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

LTBP2_HUMAN
NC score	0.066917 (rank : 156)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	82	Target Neighborhood Hits	552	Shared Neighborhood Hits	30
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TM11D_MOUSE
NC score	0.066861 (rank : 157)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

LTB1L_MOUSE
NC score	0.066638 (rank : 158)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	82	Target Neighborhood Hits	514	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBLN5_HUMAN
NC score	0.066585 (rank : 159)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	82	Target Neighborhood Hits	329	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

LTB1S_MOUSE
NC score	0.066522 (rank : 160)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	82	Target Neighborhood Hits	479	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

HEPS_HUMAN
NC score	0.066469 (rank : 161)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
NC score	0.066450 (rank : 162)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

POLS2_HUMAN
NC score	0.066028 (rank : 163)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	82	Target Neighborhood Hits	192	Shared Neighborhood Hits	18
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

TM11D_HUMAN
NC score	0.065639 (rank : 164)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

KLKB1_MOUSE
NC score	0.065563 (rank : 165)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

HGFA_HUMAN
NC score	0.065552 (rank : 166)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	82	Target Neighborhood Hits	436	Shared Neighborhood Hits	28
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

FBLN5_MOUSE
NC score	0.065534 (rank : 167)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	82	Target Neighborhood Hits	317	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

C1QR1_MOUSE
NC score	0.065401 (rank : 168)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	82	Target Neighborhood Hits	342	Shared Neighborhood Hits	22
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

ACRO_HUMAN
NC score	0.065380 (rank : 169)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	291	Shared Neighborhood Hits	17
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

FA12_HUMAN
NC score	0.065157 (rank : 170)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	82	Target Neighborhood Hits	425	Shared Neighborhood Hits	24
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA11_MOUSE
NC score	0.065102 (rank : 171)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

MATN2_HUMAN
NC score	0.065034 (rank : 172)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	82	Target Neighborhood Hits	365	Shared Neighborhood Hits	25
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

HGFA_MOUSE
NC score	0.065011 (rank : 173)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	82	Target Neighborhood Hits	419	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

TEST_MOUSE
NC score	0.064873 (rank : 174)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

EPPI_MOUSE
NC score	0.064868 (rank : 175)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	82	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DA01	Gene names	Spinlw1
Domain Architecture
Description	Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1).

POLS2_MOUSE
NC score	0.064856 (rank : 176)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	82	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

KLKB1_HUMAN
NC score	0.064800 (rank : 177)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	82	Target Neighborhood Hits	183	Shared Neighborhood Hits	17
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

FA11_HUMAN
NC score	0.064760 (rank : 178)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

PRS27_MOUSE
NC score	0.064690 (rank : 179)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

TSG6_MOUSE
NC score	0.064397 (rank : 180)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	82	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

HABP2_MOUSE
NC score	0.064384 (rank : 181)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	82	Target Neighborhood Hits	445	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

PRS27_HUMAN
NC score	0.064271 (rank : 182)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRSS8_MOUSE
NC score	0.064219 (rank : 183)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

CUZD1_MOUSE
NC score	0.064130 (rank : 184)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	82	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

ACRO_MOUSE
NC score	0.063949 (rank : 185)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	82	Target Neighborhood Hits	185	Shared Neighborhood Hits	17
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

TSG6_HUMAN
NC score	0.063836 (rank : 186)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	82	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TMSP8_MOUSE
NC score	0.063810 (rank : 187)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TSP50_HUMAN
NC score	0.063797 (rank : 188)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

TRYG1_MOUSE
NC score	0.063514 (rank : 189)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	82	Target Neighborhood Hits	181	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

WFDC8_HUMAN
NC score	0.063442 (rank : 190)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

TRYG1_HUMAN
NC score	0.063261 (rank : 191)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

BSSP4_HUMAN
NC score	0.063260 (rank : 192)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

PRSS8_HUMAN
NC score	0.063162 (rank : 193)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

AMBP_HUMAN
NC score	0.063012 (rank : 194)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	82	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	P02760, P00977, P02759	Gene names	AMBP, HCP, ITIL
Domain Architecture
Description	AMBP protein precursor [Contains: Alpha-1-microglobulin (Protein HC) (Complex-forming glycoprotein heterogeneous in charge) (Alpha-1 microglycoprotein); Inter-alpha-trypsin inhibitor light chain (ITI-LC) (Bikunin) (HI-30)].

FBLN4_HUMAN
NC score	0.062889 (rank : 195)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	82	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
NC score	0.062806 (rank : 196)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	82	Target Neighborhood Hits	270	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

AMBP_MOUSE
NC score	0.062790 (rank : 197)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	82	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q07456, Q61294	Gene names	Ambp, Itil
Domain Architecture
Description	AMBP protein precursor [Contains: Alpha-1-microglobulin; Inter-alpha- trypsin inhibitor light chain (ITI-LC) (Bikunin) (HI-30)].

MEGF6_HUMAN
NC score	0.062708 (rank : 198)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	82	Target Neighborhood Hits	671	Shared Neighborhood Hits	32
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

CUZD1_HUMAN
NC score	0.062552 (rank : 199)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	82	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

TPA_HUMAN
NC score	0.062539 (rank : 200)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	82	Target Neighborhood Hits	324	Shared Neighborhood Hits	24
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

BSSP4_MOUSE
NC score	0.062458 (rank : 201)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

TPA_MOUSE
NC score	0.062451 (rank : 202)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	82	Target Neighborhood Hits	335	Shared Neighborhood Hits	25
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

LTBP4_MOUSE
NC score	0.062159 (rank : 203)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	82	Target Neighborhood Hits	607	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

CREL1_MOUSE
NC score	0.062137 (rank : 204)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	82	Target Neighborhood Hits	524	Shared Neighborhood Hits	21
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

FBLN3_HUMAN
NC score	0.061770 (rank : 205)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	82	Target Neighborhood Hits	293	Shared Neighborhood Hits	25
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

MCPT6_MOUSE
NC score	0.061692 (rank : 206)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

CTRL_HUMAN
NC score	0.061620 (rank : 207)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

CREL1_HUMAN
NC score	0.061570 (rank : 208)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	82	Target Neighborhood Hits	441	Shared Neighborhood Hits	19
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CTRB1_HUMAN
NC score	0.061493 (rank : 209)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

MATN4_MOUSE
NC score	0.061241 (rank : 210)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	82	Target Neighborhood Hits	277	Shared Neighborhood Hits	24
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

CLCR_HUMAN
NC score	0.061078 (rank : 211)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

HABP2_HUMAN
NC score	0.061039 (rank : 212)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	82	Target Neighborhood Hits	431	Shared Neighborhood Hits	26
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

MATN4_HUMAN
NC score	0.060973 (rank : 213)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	82	Target Neighborhood Hits	287	Shared Neighborhood Hits	22
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

UROK_MOUSE
NC score	0.060711 (rank : 214)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	82	Target Neighborhood Hits	273	Shared Neighborhood Hits	23
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

LCE3B_HUMAN
NC score	0.060606 (rank : 215)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	82	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

ELA2A_MOUSE
NC score	0.060506 (rank : 216)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

TRYB1_HUMAN
NC score	0.060462 (rank : 217)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB2_HUMAN
NC score	0.060462 (rank : 218)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRYB1_MOUSE
NC score	0.060392 (rank : 219)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYA1_HUMAN
NC score	0.060272 (rank : 220)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

UROK_HUMAN
NC score	0.060059 (rank : 221)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	82	Target Neighborhood Hits	272	Shared Neighborhood Hits	24
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

TRYD_HUMAN
NC score	0.059813 (rank : 222)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

ELA2A_HUMAN
NC score	0.059766 (rank : 223)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

ELA2B_HUMAN
NC score	0.059556 (rank : 224)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

NETR_MOUSE
NC score	0.059421 (rank : 225)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	82	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

ELA3B_HUMAN
NC score	0.059351 (rank : 226)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

LTBP2_MOUSE
NC score	0.059227 (rank : 227)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	82	Target Neighborhood Hits	617	Shared Neighborhood Hits	30
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

HPT_MOUSE
NC score	0.059069 (rank : 228)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

ELA3A_HUMAN
NC score	0.059062 (rank : 229)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	82	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

GRAM_HUMAN
NC score	0.059047 (rank : 230)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

LTBP3_MOUSE
NC score	0.058972 (rank : 231)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	82	Target Neighborhood Hits	475	Shared Neighborhood Hits	29
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MATN3_HUMAN
NC score	0.058869 (rank : 232)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	82	Target Neighborhood Hits	268	Shared Neighborhood Hits	18
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

FBLN3_MOUSE
NC score	0.058701 (rank : 233)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	82	Target Neighborhood Hits	279	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

NETR_HUMAN
NC score	0.058340 (rank : 234)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	82	Target Neighborhood Hits	218	Shared Neighborhood Hits	17
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

THRB_HUMAN
NC score	0.058264 (rank : 235)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	82	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

LTBP3_HUMAN
NC score	0.058260 (rank : 236)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	82	Target Neighborhood Hits	502	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NRP2_HUMAN
NC score	0.058232 (rank : 237)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	82	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PLMN_MOUSE
NC score	0.058157 (rank : 238)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	82	Target Neighborhood Hits	208	Shared Neighborhood Hits	19
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

JAG2_HUMAN
NC score	0.058122 (rank : 239)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	82	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NELL2_HUMAN
NC score	0.057977 (rank : 240)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	82	Target Neighborhood Hits	449	Shared Neighborhood Hits	28
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NRP2_MOUSE
NC score	0.057898 (rank : 241)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	82	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

ELA1_HUMAN
NC score	0.057887 (rank : 242)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

JAG2_MOUSE
NC score	0.057852 (rank : 243)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	82	Target Neighborhood Hits	504	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR107_HUMAN
NC score	0.057849 (rank : 244)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	82	Target Neighborhood Hits	330	Shared Neighborhood Hits	23
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

MATN3_MOUSE
NC score	0.057798 (rank : 245)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	82	Target Neighborhood Hits	261	Shared Neighborhood Hits	18
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN2_MOUSE
NC score	0.057777 (rank : 246)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	82	Target Neighborhood Hits	356	Shared Neighborhood Hits	23
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

PLMN_HUMAN
NC score	0.057394 (rank : 247)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	82	Target Neighborhood Hits	204	Shared Neighborhood Hits	17
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

HPT_HUMAN
NC score	0.057365 (rank : 248)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	82	Target Neighborhood Hits	184	Shared Neighborhood Hits	18
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

THRB_MOUSE
NC score	0.057156 (rank : 249)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	82	Target Neighborhood Hits	195	Shared Neighborhood Hits	17
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

HPTR_HUMAN
NC score	0.057030 (rank : 250)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	82	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

DLL1_HUMAN
NC score	0.057020 (rank : 251)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	82	Target Neighborhood Hits	455	Shared Neighborhood Hits	37
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

APOA_HUMAN
NC score	0.056934 (rank : 252)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	82	Target Neighborhood Hits	221	Shared Neighborhood Hits	17
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

NELL2_MOUSE
NC score	0.056693 (rank : 253)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	82	Target Neighborhood Hits	436	Shared Neighborhood Hits	26
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

TRY2_MOUSE
NC score	0.056029 (rank : 254)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

PDGFD_MOUSE
NC score	0.056021 (rank : 255)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	82	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

NRP1_HUMAN
NC score	0.055433 (rank : 256)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	82	Target Neighborhood Hits	119	Shared Neighborhood Hits	18
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

TRY2_HUMAN
NC score	0.055391 (rank : 257)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

TRY1_HUMAN
NC score	0.055356 (rank : 258)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

EGFL7_HUMAN
NC score	0.055296 (rank : 259)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	82	Target Neighborhood Hits	325	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

HGFL_HUMAN
NC score	0.055153 (rank : 260)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	82	Target Neighborhood Hits	190	Shared Neighborhood Hits	17
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

NOTC1_MOUSE
NC score	0.055130 (rank : 261)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	82	Target Neighborhood Hits	916	Shared Neighborhood Hits	38
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

HGFL_MOUSE
NC score	0.055100 (rank : 262)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	82	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

DLL1_MOUSE
NC score	0.055095 (rank : 263)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	82	Target Neighborhood Hits	456	Shared Neighborhood Hits	32
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

CFAD_HUMAN
NC score	0.055066 (rank : 264)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

NELL1_HUMAN
NC score	0.055065 (rank : 265)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	82	Target Neighborhood Hits	451	Shared Neighborhood Hits	25
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

TRY3_HUMAN
NC score	0.055014 (rank : 266)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

DMBT1_MOUSE
NC score	0.054964 (rank : 267)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	82	Target Neighborhood Hits	134	Shared Neighborhood Hits	24
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

JAG1_MOUSE
NC score	0.054897 (rank : 268)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	82	Target Neighborhood Hits	518	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

CFAD_MOUSE
NC score	0.054849 (rank : 269)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

KLK14_HUMAN
NC score	0.054713 (rank : 270)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK4_HUMAN
NC score	0.054588 (rank : 271)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

KLK13_HUMAN
NC score	0.054580 (rank : 272)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

CSMD2_HUMAN
NC score	0.054571 (rank : 273)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	82	Target Neighborhood Hits	188	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

DMBT1_HUMAN
NC score	0.054527 (rank : 274)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	82	Target Neighborhood Hits	152	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

KLK6_HUMAN
NC score	0.054362 (rank : 275)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK5_HUMAN
NC score	0.054242 (rank : 276)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	82	Target Neighborhood Hits	182	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

CO2_MOUSE
NC score	0.054231 (rank : 277)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	82	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

TENX_HUMAN
NC score	0.053739 (rank : 278)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	82	Target Neighborhood Hits	789	Shared Neighborhood Hits	33
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

ELNE_HUMAN
NC score	0.053590 (rank : 279)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	82	Target Neighborhood Hits	164	Shared Neighborhood Hits	17
SwissProt Accessions	P08246, P09649, Q6B0D9, Q6LDP5	Gene names	ELA2
Domain Architecture
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase) (PMN elastase) (Bone marrow serine protease) (Medullasin) (Human leukocyte elastase) (HLE).

KLK15_HUMAN
NC score	0.053573 (rank : 280)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

NRPN_HUMAN
NC score	0.053544 (rank : 281)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	82	Target Neighborhood Hits	182	Shared Neighborhood Hits	17
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

JAG1_HUMAN
NC score	0.053519 (rank : 282)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	82	Target Neighborhood Hits	514	Shared Neighborhood Hits	31
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

KLK7_MOUSE
NC score	0.053482 (rank : 283)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

GRAK_MOUSE
NC score	0.053421 (rank : 284)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

CRUM1_HUMAN
NC score	0.053350 (rank : 285)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	82	Target Neighborhood Hits	457	Shared Neighborhood Hits	31
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

KLK7_HUMAN
NC score	0.053347 (rank : 286)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

CAP7_HUMAN
NC score	0.053210 (rank : 287)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	82	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	P20160, P80014, Q52LG4	Gene names	AZU1
Domain Architecture
Description	Azurocidin precursor (Cationic antimicrobial protein CAP37) (Heparin- binding protein) (HBP).

ELNE_MOUSE
NC score	0.053141 (rank : 288)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	82	Target Neighborhood Hits	167	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UP87, Q61515	Gene names	Ela2
Domain Architecture	No domain graphic available
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase).

PHXR5_MOUSE
NC score	0.053002 (rank : 289)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	82	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

K1KB1_MOUSE
NC score	0.052955 (rank : 290)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	19
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

KLK12_HUMAN
NC score	0.052896 (rank : 291)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	82	Target Neighborhood Hits	197	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

KLK10_HUMAN
NC score	0.052842 (rank : 292)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK11_HUMAN
NC score	0.052822 (rank : 293)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

CRUM1_MOUSE
NC score	0.052657 (rank : 294)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	82	Target Neighborhood Hits	444	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

NRP1_MOUSE
NC score	0.052634 (rank : 295)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	82	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

KLK9_HUMAN
NC score	0.052615 (rank : 296)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

PDGFD_HUMAN
NC score	0.052558 (rank : 297)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	82	Target Neighborhood Hits	74	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

KR106_HUMAN
NC score	0.052456 (rank : 298)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	82	Target Neighborhood Hits	347	Shared Neighborhood Hits	25
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

CSMD1_MOUSE
NC score	0.052433 (rank : 299)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	82	Target Neighborhood Hits	193	Shared Neighborhood Hits	23
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

K1KB9_MOUSE
NC score	0.052187 (rank : 300)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

NRPN_MOUSE
NC score	0.051982 (rank : 301)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	82	Target Neighborhood Hits	186	Shared Neighborhood Hits	18
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

KLK11_MOUSE
NC score	0.051928 (rank : 302)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

K1B26_MOUSE
NC score	0.051715 (rank : 303)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

K1B11_MOUSE
NC score	0.051660 (rank : 304)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

K1KB3_MOUSE
NC score	0.051617 (rank : 305)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

MCPT1_MOUSE
NC score	0.051560 (rank : 306)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

K1B22_MOUSE
NC score	0.051519 (rank : 307)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

EGFB2_MOUSE
NC score	0.051505 (rank : 308)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

NOTC2_MOUSE
NC score	0.051423 (rank : 309)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	82	Target Neighborhood Hits	1069	Shared Neighborhood Hits	41
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

K1B21_MOUSE
NC score	0.051422 (rank : 310)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

CATG_MOUSE
NC score	0.051334 (rank : 311)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

HGF_HUMAN
NC score	0.051306 (rank : 312)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	82	Target Neighborhood Hits	191	Shared Neighborhood Hits	17
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

NOTC2_HUMAN
NC score	0.051186 (rank : 313)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	82	Target Neighborhood Hits	1113	Shared Neighborhood Hits	39
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

K1B27_MOUSE
NC score	0.051138 (rank : 314)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

K1B24_MOUSE
NC score	0.051099 (rank : 315)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

CATG_HUMAN
NC score	0.051069 (rank : 316)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	82	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

MCPT2_MOUSE
NC score	0.050962 (rank : 317)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

NOTC4_HUMAN
NC score	0.050952 (rank : 318)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	82	Target Neighborhood Hits	905	Shared Neighborhood Hits	38
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

KLK1_MOUSE
NC score	0.050834 (rank : 319)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	82	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

ATRN_HUMAN
NC score	0.050819 (rank : 320)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	82	Target Neighborhood Hits	525	Shared Neighborhood Hits	30
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

K1KB5_MOUSE
NC score	0.050768 (rank : 321)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

MCPT4_MOUSE
NC score	0.050712 (rank : 322)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

HGF_MOUSE
NC score	0.050587 (rank : 323)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	82	Target Neighborhood Hits	192	Shared Neighborhood Hits	17
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

NOTC1_HUMAN
NC score	0.050465 (rank : 324)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	82	Target Neighborhood Hits	906	Shared Neighborhood Hits	34
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KLK2_HUMAN
NC score	0.050407 (rank : 325)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

CO2_HUMAN
NC score	0.050397 (rank : 326)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	82	Target Neighborhood Hits	258	Shared Neighborhood Hits	19
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

GRAH_HUMAN
NC score	0.050321 (rank : 327)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	82	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

K1KB8_MOUSE
NC score	0.050160 (rank : 328)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	82	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

KLK3_HUMAN
NC score	0.050055 (rank : 329)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P07288, Q16272, Q86TG8	Gene names	KLK3, APS
Domain Architecture
Description	Prostate-specific antigen precursor (EC 3.4.21.77) (PSA) (Kallikrein- 3) (Semenogelase) (Gamma-seminoprotein) (Seminin) (P-30 antigen).

CSMD1_HUMAN
NC score	0.050046 (rank : 330)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	82	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

SF04_HUMAN
NC score	0.034525 (rank : 331)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWZ8, O60378, Q6P3X9, Q8TCQ4, Q8WWT4, Q8WWT5, Q9NTG3	Gene names	SF4
Domain Architecture	No domain graphic available
Description	Splicing factor 4 (RNA-binding protein RBP).

TNR8_MOUSE
NC score	0.028476 (rank : 332)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	208	Shared Neighborhood Hits	11
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

CJ047_MOUSE
NC score	0.025271 (rank : 333)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

AFF1_MOUSE
NC score	0.021860 (rank : 334)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	351	Shared Neighborhood Hits	6
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

S39A1_MOUSE
NC score	0.020475 (rank : 335)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ03, Q99K44	Gene names	Slc39a1, Zip1, Zirtl
Domain Architecture
Description	Zinc transporter ZIP1 (Zinc-iron-regulated transporter-like) (Solute carrier family 39 member 1).

MARCS_HUMAN
NC score	0.018835 (rank : 336)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	204	Shared Neighborhood Hits	4
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

SHAN1_HUMAN
NC score	0.018360 (rank : 337)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	1041	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SQSTM_MOUSE
NC score	0.015306 (rank : 338)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q64337, Q99JM8	Gene names	Sqstm1, A170, STAP
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Ubiquitin-binding protein p62) (STONE14).

PER3_MOUSE
NC score	0.011837 (rank : 339)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

TSKS_MOUSE
NC score	0.011246 (rank : 340)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

AFF4_MOUSE
NC score	0.007266 (rank : 341)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	581	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

PCD16_HUMAN
NC score	0.004683 (rank : 342)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	245	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

KCNC4_MOUSE
NC score	0.004358 (rank : 343)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	130	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KLHL1_MOUSE
NC score	0.002578 (rank : 344)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	193	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI74	Gene names	Klhl1
Domain Architecture
Description	Kelch-like protein 1.

SPEG_MOUSE
NC score	0.000308 (rank : 345)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	1959	Shared Neighborhood Hits	8
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

KLF2_HUMAN
NC score	-0.001656 (rank : 346)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	755	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5W3, Q9UJS5, Q9UKR6	Gene names	KLF2, LKLF
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

ZN205_HUMAN
NC score	-0.002168 (rank : 347)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	743	Shared Neighborhood Hits	3
SwissProt Accessions	O95201	Gene names	ZNF205, ZNF210
Domain Architecture
Description	Zinc finger protein 205 (Zinc finger protein 210).