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Network neighborhood for query Sequence : ATRN_HUMAN

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ATRN_HUMAN
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ATRN_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	525	Target Neighborhood Hits	525	Shared Neighborhood Hits	525
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	0 (rank : 2)	NC score	0.987661 (rank : 2)
Query Neighborhood Hits	525	Target Neighborhood Hits	519	Shared Neighborhood Hits	481
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

MEGF8_MOUSE
θ value	2.11701e-41 (rank : 3)	NC score	0.682119 (rank : 3)
Query Neighborhood Hits	525	Target Neighborhood Hits	520	Shared Neighborhood Hits	318
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_HUMAN
θ value	4.27553e-34 (rank : 4)	NC score	0.670871 (rank : 4)
Query Neighborhood Hits	525	Target Neighborhood Hits	528	Shared Neighborhood Hits	318
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LAMA1_HUMAN
θ value	1.29331e-14 (rank : 5)	NC score	0.581201 (rank : 16)
Query Neighborhood Hits	525	Target Neighborhood Hits	804	Shared Neighborhood Hits	264
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	3.76295e-14 (rank : 6)	NC score	0.547727 (rank : 28)
Query Neighborhood Hits	525	Target Neighborhood Hits	1092	Shared Neighborhood Hits	265
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

BMP1_MOUSE
θ value	6.41864e-14 (rank : 7)	NC score	0.389319 (rank : 98)
Query Neighborhood Hits	525	Target Neighborhood Hits	236	Shared Neighborhood Hits	141
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

LAMA2_MOUSE
θ value	6.41864e-14 (rank : 8)	NC score	0.528249 (rank : 37)
Query Neighborhood Hits	525	Target Neighborhood Hits	1198	Shared Neighborhood Hits	274
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

BMP1_HUMAN
θ value	1.86753e-13 (rank : 9)	NC score	0.388208 (rank : 99)
Query Neighborhood Hits	525	Target Neighborhood Hits	233	Shared Neighborhood Hits	140
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

KLDC3_MOUSE
θ value	7.09661e-13 (rank : 10)	NC score	0.359676 (rank : 123)
Query Neighborhood Hits	525	Target Neighborhood Hits	77	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VEM9, Q3TCN9, Q3UR95, Q91XU6, Q99JH9, Q9DBG8	Gene names	Klhdc3, Peas
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein).

LAMA3_HUMAN
θ value	7.09661e-13 (rank : 11)	NC score	0.513000 (rank : 42)
Query Neighborhood Hits	525	Target Neighborhood Hits	760	Shared Neighborhood Hits	218
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

TLL1_MOUSE
θ value	7.09661e-13 (rank : 12)	NC score	0.390612 (rank : 96)
Query Neighborhood Hits	525	Target Neighborhood Hits	237	Shared Neighborhood Hits	139
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_MOUSE
θ value	9.26847e-13 (rank : 13)	NC score	0.380741 (rank : 106)
Query Neighborhood Hits	525	Target Neighborhood Hits	240	Shared Neighborhood Hits	140
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

LAMC1_HUMAN
θ value	1.2105e-12 (rank : 14)	NC score	0.543240 (rank : 32)
Query Neighborhood Hits	525	Target Neighborhood Hits	922	Shared Neighborhood Hits	236
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMB2_MOUSE
θ value	1.58096e-12 (rank : 15)	NC score	0.586888 (rank : 12)
Query Neighborhood Hits	525	Target Neighborhood Hits	722	Shared Neighborhood Hits	241
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMC1_MOUSE
θ value	1.58096e-12 (rank : 16)	NC score	0.561542 (rank : 23)
Query Neighborhood Hits	525	Target Neighborhood Hits	856	Shared Neighborhood Hits	242
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

TLL1_HUMAN
θ value	1.58096e-12 (rank : 17)	NC score	0.387656 (rank : 100)
Query Neighborhood Hits	525	Target Neighborhood Hits	236	Shared Neighborhood Hits	137
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

LAMB2_HUMAN
θ value	2.69671e-12 (rank : 18)	NC score	0.588340 (rank : 11)
Query Neighborhood Hits	525	Target Neighborhood Hits	692	Shared Neighborhood Hits	249
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

TLL2_HUMAN
θ value	3.52202e-12 (rank : 19)	NC score	0.383718 (rank : 102)
Query Neighborhood Hits	525	Target Neighborhood Hits	241	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CSMD2_HUMAN
θ value	4.59992e-12 (rank : 20)	NC score	0.311164 (rank : 181)
Query Neighborhood Hits	525	Target Neighborhood Hits	188	Shared Neighborhood Hits	82
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

LAMA3_MOUSE
θ value	1.02475e-11 (rank : 21)	NC score	0.552630 (rank : 26)
Query Neighborhood Hits	525	Target Neighborhood Hits	859	Shared Neighborhood Hits	252
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

USH2A_HUMAN
θ value	1.02475e-11 (rank : 22)	NC score	0.507136 (rank : 44)
Query Neighborhood Hits	525	Target Neighborhood Hits	600	Shared Neighborhood Hits	236
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LAMC3_HUMAN
θ value	1.33837e-11 (rank : 23)	NC score	0.596971 (rank : 6)
Query Neighborhood Hits	525	Target Neighborhood Hits	588	Shared Neighborhood Hits	254
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMB1_MOUSE
θ value	2.28291e-11 (rank : 24)	NC score	0.559056 (rank : 25)
Query Neighborhood Hits	525	Target Neighborhood Hits	919	Shared Neighborhood Hits	238
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

CSMD3_HUMAN
θ value	2.98157e-11 (rank : 25)	NC score	0.304363 (rank : 191)
Query Neighborhood Hits	525	Target Neighborhood Hits	199	Shared Neighborhood Hits	91
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

KLDC3_HUMAN
θ value	2.98157e-11 (rank : 26)	NC score	0.351625 (rank : 133)
Query Neighborhood Hits	525	Target Neighborhood Hits	76	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BQ90	Gene names	KLHDC3, PEAS
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein).

LAMA1_MOUSE
θ value	2.98157e-11 (rank : 27)	NC score	0.577815 (rank : 18)
Query Neighborhood Hits	525	Target Neighborhood Hits	838	Shared Neighborhood Hits	266
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA4_MOUSE
θ value	2.98157e-11 (rank : 28)	NC score	0.518152 (rank : 41)
Query Neighborhood Hits	525	Target Neighborhood Hits	584	Shared Neighborhood Hits	190
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

NTNG1_HUMAN
θ value	6.64225e-11 (rank : 29)	NC score	0.588642 (rank : 10)
Query Neighborhood Hits	525	Target Neighborhood Hits	247	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

CSMD1_MOUSE
θ value	8.67504e-11 (rank : 30)	NC score	0.309543 (rank : 182)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	94
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CUBN_HUMAN
θ value	8.67504e-11 (rank : 31)	NC score	0.545147 (rank : 31)
Query Neighborhood Hits	525	Target Neighborhood Hits	482	Shared Neighborhood Hits	292
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

NTNG1_MOUSE
θ value	8.67504e-11 (rank : 32)	NC score	0.589600 (rank : 9)
Query Neighborhood Hits	525	Target Neighborhood Hits	246	Shared Neighborhood Hits	194
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

MEGF9_MOUSE
θ value	1.133e-10 (rank : 33)	NC score	0.581521 (rank : 15)
Query Neighborhood Hits	525	Target Neighborhood Hits	896	Shared Neighborhood Hits	221
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_HUMAN
θ value	1.9326e-10 (rank : 34)	NC score	0.608603 (rank : 5)
Query Neighborhood Hits	525	Target Neighborhood Hits	557	Shared Neighborhood Hits	240
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PGBM_HUMAN
θ value	1.9326e-10 (rank : 35)	NC score	0.395050 (rank : 95)
Query Neighborhood Hits	525	Target Neighborhood Hits	1113	Shared Neighborhood Hits	284
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	1.9326e-10 (rank : 36)	NC score	0.406629 (rank : 92)
Query Neighborhood Hits	525	Target Neighborhood Hits	1073	Shared Neighborhood Hits	289
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

USH2A_MOUSE
θ value	1.9326e-10 (rank : 37)	NC score	0.512545 (rank : 43)
Query Neighborhood Hits	525	Target Neighborhood Hits	626	Shared Neighborhood Hits	238
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

LAMC3_MOUSE
θ value	2.52405e-10 (rank : 38)	NC score	0.589703 (rank : 8)
Query Neighborhood Hits	525	Target Neighborhood Hits	624	Shared Neighborhood Hits	237
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

CSMD1_HUMAN
θ value	3.29651e-10 (rank : 39)	NC score	0.305699 (rank : 189)
Query Neighborhood Hits	525	Target Neighborhood Hits	176	Shared Neighborhood Hits	88
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LAMA5_MOUSE
θ value	4.30538e-10 (rank : 40)	NC score	0.591326 (rank : 7)
Query Neighborhood Hits	525	Target Neighborhood Hits	828	Shared Neighborhood Hits	281
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NOTC1_HUMAN
θ value	5.62301e-10 (rank : 41)	NC score	0.439469 (rank : 79)
Query Neighborhood Hits	525	Target Neighborhood Hits	906	Shared Neighborhood Hits	297
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LAMC2_HUMAN
θ value	7.34386e-10 (rank : 42)	NC score	0.550313 (rank : 27)
Query Neighborhood Hits	525	Target Neighborhood Hits	715	Shared Neighborhood Hits	240
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMA5_HUMAN
θ value	1.25267e-09 (rank : 43)	NC score	0.585152 (rank : 14)
Query Neighborhood Hits	525	Target Neighborhood Hits	976	Shared Neighborhood Hits	287
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LZTR1_MOUSE
θ value	2.79066e-09 (rank : 44)	NC score	0.280052 (rank : 221)
Query Neighborhood Hits	525	Target Neighborhood Hits	200	Shared Neighborhood Hits	76
SwissProt Accessions	Q9CQ33	Gene names	Lztr1, Tcfl2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

NET2_HUMAN
θ value	3.64472e-09 (rank : 45)	NC score	0.546061 (rank : 30)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	143
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
θ value	3.64472e-09 (rank : 46)	NC score	0.547417 (rank : 29)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	145
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

SREC2_MOUSE
θ value	3.64472e-09 (rank : 47)	NC score	0.564698 (rank : 22)
Query Neighborhood Hits	525	Target Neighborhood Hits	605	Shared Neighborhood Hits	271
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

CUBN_MOUSE
θ value	4.76016e-09 (rank : 48)	NC score	0.527724 (rank : 38)
Query Neighborhood Hits	525	Target Neighborhood Hits	477	Shared Neighborhood Hits	293
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

LAMC2_MOUSE
θ value	1.06045e-08 (rank : 49)	NC score	0.564902 (rank : 21)
Query Neighborhood Hits	525	Target Neighborhood Hits	614	Shared Neighborhood Hits	238
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LZTR1_HUMAN
θ value	1.38499e-08 (rank : 50)	NC score	0.275800 (rank : 226)
Query Neighborhood Hits	525	Target Neighborhood Hits	196	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N653, Q14776	Gene names	LZTR1, TCFL2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

SREC2_HUMAN
θ value	1.80886e-08 (rank : 51)	NC score	0.560214 (rank : 24)
Query Neighborhood Hits	525	Target Neighborhood Hits	645	Shared Neighborhood Hits	270
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LAMB1_HUMAN
θ value	2.36244e-08 (rank : 52)	NC score	0.532315 (rank : 36)
Query Neighborhood Hits	525	Target Neighborhood Hits	1018	Shared Neighborhood Hits	251
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

NTNG2_HUMAN
θ value	2.36244e-08 (rank : 53)	NC score	0.586428 (rank : 13)
Query Neighborhood Hits	525	Target Neighborhood Hits	276	Shared Neighborhood Hits	212
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMA4_HUMAN
θ value	5.26297e-08 (rank : 54)	NC score	0.482292 (rank : 50)
Query Neighborhood Hits	525	Target Neighborhood Hits	708	Shared Neighborhood Hits	193
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMB3_MOUSE
θ value	6.87365e-08 (rank : 55)	NC score	0.576457 (rank : 19)
Query Neighborhood Hits	525	Target Neighborhood Hits	444	Shared Neighborhood Hits	208
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

KBTBA_HUMAN
θ value	8.97725e-08 (rank : 56)	NC score	0.205969 (rank : 318)
Query Neighborhood Hits	525	Target Neighborhood Hits	184	Shared Neighborhood Hits	69
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

NET1_MOUSE
θ value	8.97725e-08 (rank : 57)	NC score	0.520780 (rank : 40)
Query Neighborhood Hits	525	Target Neighborhood Hits	151	Shared Neighborhood Hits	117
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET4_HUMAN
θ value	1.17247e-07 (rank : 58)	NC score	0.542263 (rank : 33)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	151
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

LAMB3_HUMAN
θ value	1.53129e-07 (rank : 59)	NC score	0.567125 (rank : 20)
Query Neighborhood Hits	525	Target Neighborhood Hits	461	Shared Neighborhood Hits	190
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

NRP2_HUMAN
θ value	1.53129e-07 (rank : 60)	NC score	0.296188 (rank : 200)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	60
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NET1_HUMAN
θ value	1.99992e-07 (rank : 61)	NC score	0.521722 (rank : 39)
Query Neighborhood Hits	525	Target Neighborhood Hits	149	Shared Neighborhood Hits	120
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET4_MOUSE
θ value	1.99992e-07 (rank : 62)	NC score	0.541343 (rank : 34)
Query Neighborhood Hits	525	Target Neighborhood Hits	180	Shared Neighborhood Hits	146
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NOTC2_HUMAN
θ value	1.99992e-07 (rank : 63)	NC score	0.417792 (rank : 85)
Query Neighborhood Hits	525	Target Neighborhood Hits	1113	Shared Neighborhood Hits	302
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NTNG2_MOUSE
θ value	1.99992e-07 (rank : 64)	NC score	0.579691 (rank : 17)
Query Neighborhood Hits	525	Target Neighborhood Hits	276	Shared Neighborhood Hits	216
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

CLC4K_HUMAN
θ value	3.41135e-07 (rank : 65)	NC score	0.215619 (rank : 303)
Query Neighborhood Hits	525	Target Neighborhood Hits	172	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UJ71	Gene names	CD207, CLEC4K
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member K (Langerin) (CD207 antigen).

NOTC4_MOUSE
θ value	3.41135e-07 (rank : 66)	NC score	0.415921 (rank : 87)
Query Neighborhood Hits	525	Target Neighborhood Hits	872	Shared Neighborhood Hits	296
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

MEGF6_HUMAN
θ value	4.45536e-07 (rank : 67)	NC score	0.505731 (rank : 45)
Query Neighborhood Hits	525	Target Neighborhood Hits	671	Shared Neighborhood Hits	301
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NRP2_MOUSE
θ value	4.45536e-07 (rank : 68)	NC score	0.295574 (rank : 201)
Query Neighborhood Hits	525	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

CLC4A_HUMAN
θ value	7.59969e-07 (rank : 69)	NC score	0.218341 (rank : 299)
Query Neighborhood Hits	525	Target Neighborhood Hits	114	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UMR7, Q8WXW9, Q9H2Z9, Q9NS33, Q9UI34	Gene names	CLEC4A, CLECSF6, DCIR, LLIR
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member A (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (C-type lectin DDB27).

HCFC2_HUMAN
θ value	7.59969e-07 (rank : 70)	NC score	0.248979 (rank : 253)
Query Neighborhood Hits	525	Target Neighborhood Hits	154	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

KLH14_HUMAN
θ value	7.59969e-07 (rank : 71)	NC score	0.214926 (rank : 304)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P2G3	Gene names	KLHL14, KIAA1384
Domain Architecture	No domain graphic available
Description	Kelch-like protein 14.

LRP1B_HUMAN
θ value	7.59969e-07 (rank : 72)	NC score	0.358569 (rank : 124)
Query Neighborhood Hits	525	Target Neighborhood Hits	602	Shared Neighborhood Hits	300
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

NETO1_MOUSE
θ value	9.92553e-07 (rank : 73)	NC score	0.347298 (rank : 137)
Query Neighborhood Hits	525	Target Neighborhood Hits	109	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NOTC2_MOUSE
θ value	9.92553e-07 (rank : 74)	NC score	0.421865 (rank : 84)
Query Neighborhood Hits	525	Target Neighborhood Hits	1069	Shared Neighborhood Hits	297
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

STAB2_HUMAN
θ value	1.29631e-06 (rank : 75)	NC score	0.465977 (rank : 58)
Query Neighborhood Hits	525	Target Neighborhood Hits	534	Shared Neighborhood Hits	277
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

JAG1_MOUSE
θ value	1.69304e-06 (rank : 76)	NC score	0.474836 (rank : 53)
Query Neighborhood Hits	525	Target Neighborhood Hits	518	Shared Neighborhood Hits	287
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

NOTC1_MOUSE
θ value	1.69304e-06 (rank : 77)	NC score	0.444143 (rank : 74)
Query Neighborhood Hits	525	Target Neighborhood Hits	916	Shared Neighborhood Hits	296
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NRP1_HUMAN
θ value	1.69304e-06 (rank : 78)	NC score	0.285431 (rank : 215)
Query Neighborhood Hits	525	Target Neighborhood Hits	119	Shared Neighborhood Hits	59
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

TENX_HUMAN
θ value	1.69304e-06 (rank : 79)	NC score	0.413688 (rank : 90)
Query Neighborhood Hits	525	Target Neighborhood Hits	789	Shared Neighborhood Hits	284
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

HCFC1_HUMAN
θ value	2.21117e-06 (rank : 80)	NC score	0.221257 (rank : 294)
Query Neighborhood Hits	525	Target Neighborhood Hits	331	Shared Neighborhood Hits	61
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

NRP1_MOUSE
θ value	2.88788e-06 (rank : 81)	NC score	0.284460 (rank : 216)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	58
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

STAB2_MOUSE
θ value	2.88788e-06 (rank : 82)	NC score	0.460386 (rank : 63)
Query Neighborhood Hits	525	Target Neighborhood Hits	528	Shared Neighborhood Hits	283
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TENA_MOUSE
θ value	2.88788e-06 (rank : 83)	NC score	0.407418 (rank : 91)
Query Neighborhood Hits	525	Target Neighborhood Hits	596	Shared Neighborhood Hits	266
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

MKLN1_HUMAN
θ value	3.77169e-06 (rank : 84)	NC score	0.203056 (rank : 326)
Query Neighborhood Hits	525	Target Neighborhood Hits	53	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UL63, Q9NSK4, Q9NUS8	Gene names	MKLN1
Domain Architecture
Description	Muskelin.

MKLN1_MOUSE
θ value	3.77169e-06 (rank : 85)	NC score	0.202105 (rank : 328)
Query Neighborhood Hits	525	Target Neighborhood Hits	54	Shared Neighborhood Hits	46
SwissProt Accessions	O89050	Gene names	Mkln1
Domain Architecture
Description	Muskelin.

NETO1_HUMAN
θ value	4.92598e-06 (rank : 86)	NC score	0.343663 (rank : 139)
Query Neighborhood Hits	525	Target Neighborhood Hits	110	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NOTC3_MOUSE
θ value	4.92598e-06 (rank : 87)	NC score	0.430199 (rank : 82)
Query Neighborhood Hits	525	Target Neighborhood Hits	975	Shared Neighborhood Hits	305
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ST14_HUMAN
θ value	4.92598e-06 (rank : 88)	NC score	0.189576 (rank : 357)
Query Neighborhood Hits	525	Target Neighborhood Hits	409	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

HCFC1_MOUSE
θ value	6.43352e-06 (rank : 89)	NC score	0.217642 (rank : 301)
Query Neighborhood Hits	525	Target Neighborhood Hits	348	Shared Neighborhood Hits	64
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

KLHL5_HUMAN
θ value	6.43352e-06 (rank : 90)	NC score	0.192012 (rank : 350)
Query Neighborhood Hits	525	Target Neighborhood Hits	188	Shared Neighborhood Hits	66
SwissProt Accessions	Q96PQ7, Q86XW0, Q9NUK3, Q9NV27, Q9NVA9, Q9Y2X2	Gene names	KLHL5
Domain Architecture
Description	Kelch-like protein 5.

TENR_MOUSE
θ value	6.43352e-06 (rank : 91)	NC score	0.318367 (rank : 174)
Query Neighborhood Hits	525	Target Neighborhood Hits	531	Shared Neighborhood Hits	243
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

CLC1A_HUMAN
θ value	8.40245e-06 (rank : 92)	NC score	0.195552 (rank : 343)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NC01, Q8IUW7, Q9NZH3	Gene names	CLEC1A, CLEC1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 1 member A (C-type lectin-like receptor 1) (CLEC-1).

ENC1_MOUSE
θ value	8.40245e-06 (rank : 93)	NC score	0.209171 (rank : 311)
Query Neighborhood Hits	525	Target Neighborhood Hits	190	Shared Neighborhood Hits	72
SwissProt Accessions	O35709	Gene names	Enc1, Enc-1
Domain Architecture
Description	Ectoderm-neural cortex 1 protein (ENC-1).

JAG1_HUMAN
θ value	8.40245e-06 (rank : 94)	NC score	0.473987 (rank : 54)
Query Neighborhood Hits	525	Target Neighborhood Hits	514	Shared Neighborhood Hits	291
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

LRP1B_MOUSE
θ value	8.40245e-06 (rank : 95)	NC score	0.355019 (rank : 129)
Query Neighborhood Hits	525	Target Neighborhood Hits	606	Shared Neighborhood Hits	299
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

NETO2_HUMAN
θ value	8.40245e-06 (rank : 96)	NC score	0.339519 (rank : 144)
Query Neighborhood Hits	525	Target Neighborhood Hits	109	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NOTC4_HUMAN
θ value	8.40245e-06 (rank : 97)	NC score	0.415032 (rank : 89)
Query Neighborhood Hits	525	Target Neighborhood Hits	905	Shared Neighborhood Hits	303
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

KEAP1_MOUSE
θ value	1.43324e-05 (rank : 98)	NC score	0.196586 (rank : 340)
Query Neighborhood Hits	525	Target Neighborhood Hits	182	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z2X8	Gene names	Keap1
Domain Architecture
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2).

MFRP_HUMAN
θ value	1.43324e-05 (rank : 99)	NC score	0.315800 (rank : 175)
Query Neighborhood Hits	525	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NAGPA_MOUSE
θ value	1.87187e-05 (rank : 100)	NC score	0.489076 (rank : 49)
Query Neighborhood Hits	525	Target Neighborhood Hits	308	Shared Neighborhood Hits	220
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

TENR_HUMAN
θ value	1.87187e-05 (rank : 101)	NC score	0.312012 (rank : 179)
Query Neighborhood Hits	525	Target Neighborhood Hits	526	Shared Neighborhood Hits	242
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

MFRP_MOUSE
θ value	2.44474e-05 (rank : 102)	NC score	0.302681 (rank : 193)
Query Neighborhood Hits	525	Target Neighborhood Hits	166	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

FBX42_HUMAN
θ value	3.19293e-05 (rank : 103)	NC score	0.234692 (rank : 275)
Query Neighborhood Hits	525	Target Neighborhood Hits	121	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

NOTC3_HUMAN
θ value	3.19293e-05 (rank : 104)	NC score	0.427616 (rank : 83)
Query Neighborhood Hits	525	Target Neighborhood Hits	1062	Shared Neighborhood Hits	301
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

DLL4_MOUSE
θ value	4.1701e-05 (rank : 105)	NC score	0.476328 (rank : 51)
Query Neighborhood Hits	525	Target Neighborhood Hits	440	Shared Neighborhood Hits	271
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DMBT1_MOUSE
θ value	4.1701e-05 (rank : 106)	NC score	0.250899 (rank : 249)
Query Neighborhood Hits	525	Target Neighborhood Hits	134	Shared Neighborhood Hits	54
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

ENC1_HUMAN
θ value	5.44631e-05 (rank : 107)	NC score	0.205054 (rank : 322)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	72
SwissProt Accessions	O14682, O75464, Q9UPG9	Gene names	ENC1, NRPB, PIG10
Domain Architecture
Description	Ectoderm-neural cortex 1 protein (ENC-1) (p53-induced protein 10) (Nuclear matrix protein NRP/B).

JAG2_MOUSE
θ value	5.44631e-05 (rank : 108)	NC score	0.466679 (rank : 56)
Query Neighborhood Hits	525	Target Neighborhood Hits	504	Shared Neighborhood Hits	282
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

MRC1_HUMAN
θ value	5.44631e-05 (rank : 109)	NC score	0.175577 (rank : 402)
Query Neighborhood Hits	525	Target Neighborhood Hits	157	Shared Neighborhood Hits	65
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

PCOC2_MOUSE
θ value	5.44631e-05 (rank : 110)	NC score	0.331837 (rank : 157)
Query Neighborhood Hits	525	Target Neighborhood Hits	73	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

ST14_MOUSE
θ value	5.44631e-05 (rank : 111)	NC score	0.186163 (rank : 363)
Query Neighborhood Hits	525	Target Neighborhood Hits	419	Shared Neighborhood Hits	175
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

STAB1_HUMAN
θ value	5.44631e-05 (rank : 112)	NC score	0.465464 (rank : 59)
Query Neighborhood Hits	525	Target Neighborhood Hits	546	Shared Neighborhood Hits	284
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

CLC1A_MOUSE
θ value	7.1131e-05 (rank : 113)	NC score	0.169922 (rank : 426)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BWY2, Q7TPX7, Q8BMH5	Gene names	Clec1a
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 1 member A.

FBX42_MOUSE
θ value	7.1131e-05 (rank : 114)	NC score	0.238586 (rank : 269)
Query Neighborhood Hits	525	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PDJ6, Q8CE76, Q99KY2	Gene names	Fbxo42
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

KEAP1_HUMAN
θ value	7.1131e-05 (rank : 115)	NC score	0.196214 (rank : 341)
Query Neighborhood Hits	525	Target Neighborhood Hits	181	Shared Neighborhood Hits	68
SwissProt Accessions	Q14145, Q6LEP0	Gene names	KEAP1, KIAA0132, KLHL19
Domain Architecture	No domain graphic available
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (Kelch-like protein 19).

SREC_HUMAN
θ value	7.1131e-05 (rank : 116)	NC score	0.540111 (rank : 35)
Query Neighborhood Hits	525	Target Neighborhood Hits	645	Shared Neighborhood Hits	275
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

JAG2_HUMAN
θ value	9.29e-05 (rank : 117)	NC score	0.463603 (rank : 60)
Query Neighborhood Hits	525	Target Neighborhood Hits	491	Shared Neighborhood Hits	279
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

STAB1_MOUSE
θ value	9.29e-05 (rank : 118)	NC score	0.461677 (rank : 62)
Query Neighborhood Hits	525	Target Neighborhood Hits	566	Shared Neighborhood Hits	286
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

DLL4_HUMAN
θ value	0.000121331 (rank : 119)	NC score	0.473610 (rank : 55)
Query Neighborhood Hits	525	Target Neighborhood Hits	435	Shared Neighborhood Hits	271
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

MRC1_MOUSE
θ value	0.000121331 (rank : 120)	NC score	0.176323 (rank : 398)
Query Neighborhood Hits	525	Target Neighborhood Hits	156	Shared Neighborhood Hits	63
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

NETO2_MOUSE
θ value	0.000121331 (rank : 121)	NC score	0.333218 (rank : 152)
Query Neighborhood Hits	525	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

PCOC2_HUMAN
θ value	0.000158464 (rank : 122)	NC score	0.327829 (rank : 162)
Query Neighborhood Hits	525	Target Neighborhood Hits	73	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

WIF1_HUMAN
θ value	0.000158464 (rank : 123)	NC score	0.494259 (rank : 48)
Query Neighborhood Hits	525	Target Neighborhood Hits	392	Shared Neighborhood Hits	272
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

DMBT1_HUMAN
θ value	0.00020696 (rank : 124)	NC score	0.219077 (rank : 296)
Query Neighborhood Hits	525	Target Neighborhood Hits	152	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

ENTK_MOUSE
θ value	0.000270298 (rank : 125)	NC score	0.139018 (rank : 529)
Query Neighborhood Hits	525	Target Neighborhood Hits	338	Shared Neighborhood Hits	92
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

OLR1_HUMAN
θ value	0.000270298 (rank : 126)	NC score	0.180816 (rank : 384)
Query Neighborhood Hits	525	Target Neighborhood Hits	152	Shared Neighborhood Hits	57
SwissProt Accessions	P78380, Q2PP00, Q7Z484	Gene names	OLR1, LOX1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) (hLOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

TIE1_MOUSE
θ value	0.000270298 (rank : 127)	NC score	0.158310 (rank : 466)
Query Neighborhood Hits	525	Target Neighborhood Hits	1266	Shared Neighborhood Hits	238
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

KLHL1_MOUSE
θ value	0.00035302 (rank : 128)	NC score	0.191905 (rank : 352)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JI74	Gene names	Klhl1
Domain Architecture
Description	Kelch-like protein 1.

LRP12_MOUSE
θ value	0.00035302 (rank : 129)	NC score	0.298773 (rank : 196)
Query Neighborhood Hits	525	Target Neighborhood Hits	180	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

PGCB_HUMAN
θ value	0.00035302 (rank : 130)	NC score	0.268460 (rank : 236)
Query Neighborhood Hits	525	Target Neighborhood Hits	478	Shared Neighborhood Hits	208
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

TENA_HUMAN
θ value	0.00035302 (rank : 131)	NC score	0.403742 (rank : 94)
Query Neighborhood Hits	525	Target Neighborhood Hits	631	Shared Neighborhood Hits	270
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENN_HUMAN
θ value	0.00035302 (rank : 132)	NC score	0.277085 (rank : 223)
Query Neighborhood Hits	525	Target Neighborhood Hits	453	Shared Neighborhood Hits	217
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	0.00035302 (rank : 133)	NC score	0.273790 (rank : 230)
Query Neighborhood Hits	525	Target Neighborhood Hits	484	Shared Neighborhood Hits	220
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

LYAM2_HUMAN
θ value	0.000461057 (rank : 134)	NC score	0.303380 (rank : 192)
Query Neighborhood Hits	525	Target Neighborhood Hits	394	Shared Neighborhood Hits	231
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

WIF1_MOUSE
θ value	0.000602161 (rank : 135)	NC score	0.495160 (rank : 47)
Query Neighborhood Hits	525	Target Neighborhood Hits	393	Shared Neighborhood Hits	266
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

AGRIN_HUMAN
θ value	0.000786445 (rank : 136)	NC score	0.500651 (rank : 46)
Query Neighborhood Hits	525	Target Neighborhood Hits	582	Shared Neighborhood Hits	267
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CELR1_MOUSE
θ value	0.000786445 (rank : 137)	NC score	0.248758 (rank : 255)
Query Neighborhood Hits	525	Target Neighborhood Hits	617	Shared Neighborhood Hits	258
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR2_MOUSE
θ value	0.000786445 (rank : 138)	NC score	0.240364 (rank : 267)
Query Neighborhood Hits	525	Target Neighborhood Hits	584	Shared Neighborhood Hits	236
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

KLHL1_HUMAN
θ value	0.000786445 (rank : 139)	NC score	0.191493 (rank : 353)
Query Neighborhood Hits	525	Target Neighborhood Hits	195	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NR64, Q5VZ64, Q9H4X4, Q9NR65, Q9P238	Gene names	KLHL1, KIAA1490
Domain Architecture
Description	Kelch-like protein 1.

NAGPA_HUMAN
θ value	0.000786445 (rank : 140)	NC score	0.476189 (rank : 52)
Query Neighborhood Hits	525	Target Neighborhood Hits	282	Shared Neighborhood Hits	211
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

SLIT1_MOUSE
θ value	0.000786445 (rank : 141)	NC score	0.332488 (rank : 154)
Query Neighborhood Hits	525	Target Neighborhood Hits	715	Shared Neighborhood Hits	265
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

EGFL7_HUMAN
θ value	0.00102713 (rank : 142)	NC score	0.385938 (rank : 101)
Query Neighborhood Hits	525	Target Neighborhood Hits	325	Shared Neighborhood Hits	226
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

TIE2_HUMAN
θ value	0.00102713 (rank : 143)	NC score	0.143784 (rank : 509)
Query Neighborhood Hits	525	Target Neighborhood Hits	1192	Shared Neighborhood Hits	231
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	0.00102713 (rank : 144)	NC score	0.140909 (rank : 521)
Query Neighborhood Hits	525	Target Neighborhood Hits	1204	Shared Neighborhood Hits	232
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

CLC10_HUMAN
θ value	0.00134147 (rank : 145)	NC score	0.186012 (rank : 365)
Query Neighborhood Hits	525	Target Neighborhood Hits	134	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IUN9, Q14538, Q6PIW3	Gene names	CLEC10A, CLECSF14, HML
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD301 antigen).

CLC6A_MOUSE
θ value	0.00134147 (rank : 146)	NC score	0.199014 (rank : 332)
Query Neighborhood Hits	525	Target Neighborhood Hits	111	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JKF4, Q9JKF2, Q9JKF3	Gene names	Clec6a, Clecsf10, Dectin2
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated lectin 2) (DC-associated C-type lectin-2) (DECTIN-2).

KLH13_MOUSE
θ value	0.00134147 (rank : 147)	NC score	0.198868 (rank : 334)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	72
SwissProt Accessions	Q80TF4, Q9DBY7	Gene names	Klhl13, Bklhd2, Kiaa1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

KLHL9_MOUSE
θ value	0.00134147 (rank : 148)	NC score	0.197225 (rank : 338)
Query Neighborhood Hits	525	Target Neighborhood Hits	195	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZPT1	Gene names	Klhl9, Kiaa1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

LY75_MOUSE
θ value	0.00134147 (rank : 149)	NC score	0.156702 (rank : 470)
Query Neighborhood Hits	525	Target Neighborhood Hits	155	Shared Neighborhood Hits	64
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

SLIT1_HUMAN
θ value	0.00134147 (rank : 150)	NC score	0.332190 (rank : 155)
Query Neighborhood Hits	525	Target Neighborhood Hits	700	Shared Neighborhood Hits	262
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

TSG6_MOUSE
θ value	0.00175202 (rank : 151)	NC score	0.323323 (rank : 163)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	64
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

C209A_MOUSE
θ value	0.00228821 (rank : 152)	NC score	0.174738 (rank : 404)
Query Neighborhood Hits	525	Target Neighborhood Hits	117	Shared Neighborhood Hits	59
SwissProt Accessions	Q91ZX1, Q3TAT9, Q91ZW5	Gene names	Cd209a, Cire
Domain Architecture
Description	CD209 antigen-like protein A (Dendritic cell-specific ICAM-3-grabbing nonintegrin) (DC-SIGN).

ITB6_HUMAN
θ value	0.00228821 (rank : 153)	NC score	0.360697 (rank : 122)
Query Neighborhood Hits	525	Target Neighborhood Hits	318	Shared Neighborhood Hits	219
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

KHL15_HUMAN
θ value	0.00228821 (rank : 154)	NC score	0.191973 (rank : 351)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	70
SwissProt Accessions	Q96M94, Q32MN3, Q8NDA3, Q96BM6, Q9C0I6	Gene names	KLHL15, KIAA1677
Domain Architecture	No domain graphic available
Description	Kelch-like protein 15.

LRP12_HUMAN
θ value	0.00228821 (rank : 155)	NC score	0.299208 (rank : 195)
Query Neighborhood Hits	525	Target Neighborhood Hits	205	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

CLC4C_HUMAN
θ value	0.00298849 (rank : 156)	NC score	0.192487 (rank : 348)
Query Neighborhood Hits	525	Target Neighborhood Hits	111	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WTT0, Q3T1C3, Q6UXS8, Q8WXX8	Gene names	CLEC4C, BDCA2, CLECSF11, CLECSF7, DLEC, HECL
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member C (C-type lectin superfamily member 7) (Blood dendritic cell antigen 2 protein) (BDCA-2) (Dendritic lectin) (CD303 antigen).

CLC4E_MOUSE
θ value	0.00298849 (rank : 157)	NC score	0.188402 (rank : 359)
Query Neighborhood Hits	525	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R0Q8	Gene names	Clec4e, Clecsf9, Mincle
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).

KLDC4_MOUSE
θ value	0.00298849 (rank : 158)	NC score	0.202512 (rank : 327)
Query Neighborhood Hits	525	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q921I2, Q8CIK0	Gene names	Klhdc4
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 4.

LTBP3_HUMAN
θ value	0.00298849 (rank : 159)	NC score	0.357753 (rank : 126)
Query Neighborhood Hits	525	Target Neighborhood Hits	502	Shared Neighborhood Hits	266
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

PGCB_MOUSE
θ value	0.00298849 (rank : 160)	NC score	0.266488 (rank : 238)
Query Neighborhood Hits	525	Target Neighborhood Hits	459	Shared Neighborhood Hits	210
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

SLIT2_HUMAN
θ value	0.00298849 (rank : 161)	NC score	0.319790 (rank : 170)
Query Neighborhood Hits	525	Target Neighborhood Hits	708	Shared Neighborhood Hits	267
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TIE1_HUMAN
θ value	0.00298849 (rank : 162)	NC score	0.161362 (rank : 456)
Query Neighborhood Hits	525	Target Neighborhood Hits	1241	Shared Neighborhood Hits	241
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CLC4D_HUMAN
θ value	0.00390308 (rank : 163)	NC score	0.184557 (rank : 373)
Query Neighborhood Hits	525	Target Neighborhood Hits	111	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WXI8, Q8N5J5	Gene names	CLEC4D, CLECSF8, MCL
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member D (C-type lectin superfamily member 8) (C-type lectin-like receptor 6) (CLEC-6).

EGFL7_MOUSE
θ value	0.00390308 (rank : 164)	NC score	0.369234 (rank : 117)
Query Neighborhood Hits	525	Target Neighborhood Hits	287	Shared Neighborhood Hits	211
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

HABP2_HUMAN
θ value	0.00390308 (rank : 165)	NC score	0.214313 (rank : 305)
Query Neighborhood Hits	525	Target Neighborhood Hits	431	Shared Neighborhood Hits	215
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

ITB5_MOUSE
θ value	0.00390308 (rank : 166)	NC score	0.356646 (rank : 127)
Query Neighborhood Hits	525	Target Neighborhood Hits	329	Shared Neighborhood Hits	228
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

LTBP3_MOUSE
θ value	0.00390308 (rank : 167)	NC score	0.362544 (rank : 121)
Query Neighborhood Hits	525	Target Neighborhood Hits	475	Shared Neighborhood Hits	270
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LYAM2_MOUSE
θ value	0.00390308 (rank : 168)	NC score	0.321297 (rank : 168)
Query Neighborhood Hits	525	Target Neighborhood Hits	420	Shared Neighborhood Hits	247
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

REG4_MOUSE
θ value	0.00390308 (rank : 169)	NC score	0.171078 (rank : 422)
Query Neighborhood Hits	525	Target Neighborhood Hits	101	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D8G5, Q3TS25, Q9D858	Gene names	Reg4
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 4 precursor.

CELR2_HUMAN
θ value	0.00509761 (rank : 170)	NC score	0.256209 (rank : 246)
Query Neighborhood Hits	525	Target Neighborhood Hits	657	Shared Neighborhood Hits	265
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CUZD1_HUMAN
θ value	0.00509761 (rank : 171)	NC score	0.281048 (rank : 219)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

KLHL7_HUMAN
θ value	0.00509761 (rank : 172)	NC score	0.179437 (rank : 388)
Query Neighborhood Hits	525	Target Neighborhood Hits	176	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IXQ5, Q9BQF8	Gene names	KLHL7
Domain Architecture	No domain graphic available
Description	Kelch-like protein 7.

ASGR1_MOUSE
θ value	0.00665767 (rank : 173)	NC score	0.171936 (rank : 417)
Query Neighborhood Hits	525	Target Neighborhood Hits	135	Shared Neighborhood Hits	59
SwissProt Accessions	P34927, Q64363	Gene names	Asgr1, Asgr-1
Domain Architecture
Description	Asialoglycoprotein receptor 1 (ASGPR 1) (ASGP-R 1) (Hepatic lectin 1) (MHL-1).

CLC4K_MOUSE
θ value	0.00665767 (rank : 174)	NC score	0.186099 (rank : 364)
Query Neighborhood Hits	525	Target Neighborhood Hits	165	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VBX4, Q8R442	Gene names	Cd207, Clec4k
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member K (Langerin) (CD207 antigen).

CRUM2_HUMAN
θ value	0.00665767 (rank : 175)	NC score	0.448216 (rank : 72)
Query Neighborhood Hits	525	Target Neighborhood Hits	453	Shared Neighborhood Hits	272
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

ITB1_HUMAN
θ value	0.00665767 (rank : 176)	NC score	0.340245 (rank : 142)
Query Neighborhood Hits	525	Target Neighborhood Hits	298	Shared Neighborhood Hits	217
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KLHL9_HUMAN
θ value	0.00665767 (rank : 177)	NC score	0.195560 (rank : 342)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P2J3, Q8TCQ2	Gene names	KLHL9, KIAA1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

MRC2_HUMAN
θ value	0.00665767 (rank : 178)	NC score	0.167184 (rank : 439)
Query Neighborhood Hits	525	Target Neighborhood Hits	162	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UBG0, Q7LGE7, Q9Y5P9	Gene names	MRC2, ENDO180, KIAA0709, UPARAP
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Urokinase receptor-associated protein) (Endocytic receptor 180) (CD280 antigen).

SLIT2_MOUSE
θ value	0.00665767 (rank : 179)	NC score	0.312771 (rank : 177)
Query Neighborhood Hits	525	Target Neighborhood Hits	684	Shared Neighborhood Hits	249
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TSG6_HUMAN
θ value	0.00665767 (rank : 180)	NC score	0.322909 (rank : 165)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	64
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

ITB4_HUMAN
θ value	0.00869519 (rank : 181)	NC score	0.328476 (rank : 159)
Query Neighborhood Hits	525	Target Neighborhood Hits	458	Shared Neighborhood Hits	221
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KLH12_MOUSE
θ value	0.00869519 (rank : 182)	NC score	0.183483 (rank : 376)
Query Neighborhood Hits	525	Target Neighborhood Hits	190	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BZM0, Q8K225	Gene names	Klhl12, C3ip1
Domain Architecture	No domain graphic available
Description	Kelch-like protein 12 (CUL3-interacting protein 1).

KLHL7_MOUSE
θ value	0.00869519 (rank : 183)	NC score	0.179397 (rank : 389)
Query Neighborhood Hits	525	Target Neighborhood Hits	179	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BUL5, Q9CZP4	Gene names	Klhl7
Domain Architecture	No domain graphic available
Description	Kelch-like protein 7.

LRP1_HUMAN
θ value	0.00869519 (rank : 184)	NC score	0.351743 (rank : 132)
Query Neighborhood Hits	525	Target Neighborhood Hits	617	Shared Neighborhood Hits	302
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

MMGL_MOUSE
θ value	0.00869519 (rank : 185)	NC score	0.171183 (rank : 420)
Query Neighborhood Hits	525	Target Neighborhood Hits	270	Shared Neighborhood Hits	57
SwissProt Accessions	P49300	Gene names	Mgl1, Mgl
Domain Architecture
Description	Macrophage asialoglycoprotein-binding protein 1 (M-ASGP-BP) (Macrophage galactose/N-acetylgalactosamine-specific lectin) (MMGL).

CLC9A_HUMAN
θ value	0.0113563 (rank : 186)	NC score	0.177632 (rank : 393)
Query Neighborhood Hits	525	Target Neighborhood Hits	95	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UXN8	Gene names	CLEC9A
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 9 member A.

ENTK_HUMAN
θ value	0.0113563 (rank : 187)	NC score	0.119472 (rank : 561)
Query Neighborhood Hits	525	Target Neighborhood Hits	310	Shared Neighborhood Hits	84
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

FBN3_HUMAN
θ value	0.0113563 (rank : 188)	NC score	0.381053 (rank : 105)
Query Neighborhood Hits	525	Target Neighborhood Hits	543	Shared Neighborhood Hits	283
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GAN_HUMAN
θ value	0.0113563 (rank : 189)	NC score	0.186228 (rank : 362)
Query Neighborhood Hits	525	Target Neighborhood Hits	180	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H2C0	Gene names	GAN, GAN1, KLHL16
Domain Architecture
Description	Gigaxonin (Kelch-like protein 16).

KLH12_HUMAN
θ value	0.0113563 (rank : 190)	NC score	0.183280 (rank : 378)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	67
SwissProt Accessions	Q53G59, Q9HBX5	Gene names	KLHL12, C3IP1
Domain Architecture	No domain graphic available
Description	Kelch-like protein 12 (CUL3-interacting protein 1).

LYAM1_HUMAN
θ value	0.0113563 (rank : 191)	NC score	0.293492 (rank : 204)
Query Neighborhood Hits	525	Target Neighborhood Hits	315	Shared Neighborhood Hits	195
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

PCOC1_MOUSE
θ value	0.0113563 (rank : 192)	NC score	0.313514 (rank : 176)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

C209E_MOUSE
θ value	0.0148317 (rank : 193)	NC score	0.170293 (rank : 425)
Query Neighborhood Hits	525	Target Neighborhood Hits	117	Shared Neighborhood Hits	57
SwissProt Accessions	Q91ZW7	Gene names	Cd209e
Domain Architecture
Description	CD209 antigen-like protein E (DC-SIGN-related protein 4) (DC-SIGNR4).

DLL3_HUMAN
θ value	0.0148317 (rank : 194)	NC score	0.456418 (rank : 66)
Query Neighborhood Hits	525	Target Neighborhood Hits	419	Shared Neighborhood Hits	259
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DNER_HUMAN
θ value	0.0148317 (rank : 195)	NC score	0.454574 (rank : 67)
Query Neighborhood Hits	525	Target Neighborhood Hits	460	Shared Neighborhood Hits	266
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

EGFL8_MOUSE
θ value	0.0148317 (rank : 196)	NC score	0.321934 (rank : 167)
Query Neighborhood Hits	525	Target Neighborhood Hits	266	Shared Neighborhood Hits	185
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

FRAS1_MOUSE
θ value	0.0148317 (rank : 197)	NC score	0.287643 (rank : 213)
Query Neighborhood Hits	525	Target Neighborhood Hits	747	Shared Neighborhood Hits	231
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ITB7_HUMAN
θ value	0.0148317 (rank : 198)	NC score	0.354683 (rank : 130)
Query Neighborhood Hits	525	Target Neighborhood Hits	290	Shared Neighborhood Hits	219
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

CD69_HUMAN
θ value	0.0193708 (rank : 199)	NC score	0.165814 (rank : 443)
Query Neighborhood Hits	525	Target Neighborhood Hits	99	Shared Neighborhood Hits	52
SwissProt Accessions	Q07108	Gene names	CD69
Domain Architecture
Description	Early activation antigen CD69 (Early T-cell activation antigen p60) (GP32/28) (Leu-23) (MLR-3) (EA1) (BL-AC/P26) (Activation inducer molecule) (AIM).

CSPG3_HUMAN
θ value	0.0193708 (rank : 200)	NC score	0.343436 (rank : 140)
Query Neighborhood Hits	525	Target Neighborhood Hits	676	Shared Neighborhood Hits	262
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

FBN1_MOUSE
θ value	0.0193708 (rank : 201)	NC score	0.377887 (rank : 107)
Query Neighborhood Hits	525	Target Neighborhood Hits	563	Shared Neighborhood Hits	284
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

KLH10_MOUSE
θ value	0.0193708 (rank : 202)	NC score	0.185047 (rank : 371)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D5V2, Q8BVM3, Q9DA07	Gene names	Klhl10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

KLH13_HUMAN
θ value	0.0193708 (rank : 203)	NC score	0.192966 (rank : 345)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P2N7, Q6P2E3, Q96QI7, Q9UDN9	Gene names	KLHL13, BKLHD2, KIAA1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

KRA98_HUMAN
θ value	0.0193708 (rank : 204)	NC score	0.260180 (rank : 244)
Query Neighborhood Hits	525	Target Neighborhood Hits	185	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

MRC2_MOUSE
θ value	0.0193708 (rank : 205)	NC score	0.165029 (rank : 445)
Query Neighborhood Hits	525	Target Neighborhood Hits	159	Shared Neighborhood Hits	62
SwissProt Accessions	Q64449, Q6ZQ64, Q8C6P0	Gene names	Mrc2, Kiaa0709
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Lectin lambda) (CD280 antigen).

ASGR1_HUMAN
θ value	0.0252991 (rank : 206)	NC score	0.169551 (rank : 430)
Query Neighborhood Hits	525	Target Neighborhood Hits	137	Shared Neighborhood Hits	60
SwissProt Accessions	P07306	Gene names	ASGR1
Domain Architecture
Description	Asialoglycoprotein receptor 1 (ASGPR 1) (ASGP-R 1) (Hepatic lectin H1).

HHIP_MOUSE
θ value	0.0252991 (rank : 207)	NC score	0.369385 (rank : 114)
Query Neighborhood Hits	525	Target Neighborhood Hits	219	Shared Neighborhood Hits	185
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB1_MOUSE
θ value	0.0252991 (rank : 208)	NC score	0.336220 (rank : 148)
Query Neighborhood Hits	525	Target Neighborhood Hits	283	Shared Neighborhood Hits	212
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB5_HUMAN
θ value	0.0252991 (rank : 209)	NC score	0.347728 (rank : 136)
Query Neighborhood Hits	525	Target Neighborhood Hits	310	Shared Neighborhood Hits	215
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB7_MOUSE
θ value	0.0252991 (rank : 210)	NC score	0.355508 (rank : 128)
Query Neighborhood Hits	525	Target Neighborhood Hits	277	Shared Neighborhood Hits	213
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

KLH20_HUMAN
θ value	0.0252991 (rank : 211)	NC score	0.176174 (rank : 400)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y2M5, Q5TZF2, Q9H457	Gene names	KLHL20, KLEIP
Domain Architecture
Description	Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch- like protein X).

KLH20_MOUSE
θ value	0.0252991 (rank : 212)	NC score	0.176197 (rank : 399)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VCK5, Q8BWA2	Gene names	Klhl20, Kleip
Domain Architecture	No domain graphic available
Description	Kelch-like protein 20 (Kelch-like ECT2-interacting protein).

PLXA3_HUMAN
θ value	0.0252991 (rank : 213)	NC score	0.075035 (rank : 703)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	P51805	Gene names	PLXNA3, PLXN4, SEX
Domain Architecture
Description	Plexin-A3 precursor (Plexin-4) (Semaphorin receptor SEX).

TSP3_HUMAN
θ value	0.0252991 (rank : 214)	NC score	0.289688 (rank : 211)
Query Neighborhood Hits	525	Target Neighborhood Hits	250	Shared Neighborhood Hits	168
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	0.0252991 (rank : 215)	NC score	0.297322 (rank : 198)
Query Neighborhood Hits	525	Target Neighborhood Hits	247	Shared Neighborhood Hits	174
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

CELR1_HUMAN
θ value	0.0330416 (rank : 216)	NC score	0.243741 (rank : 262)
Query Neighborhood Hits	525	Target Neighborhood Hits	613	Shared Neighborhood Hits	249
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CUZD1_MOUSE
θ value	0.0330416 (rank : 217)	NC score	0.273217 (rank : 231)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	50
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DLL3_MOUSE
θ value	0.0330416 (rank : 218)	NC score	0.452406 (rank : 69)
Query Neighborhood Hits	525	Target Neighborhood Hits	399	Shared Neighborhood Hits	259
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

HABP2_MOUSE
θ value	0.0330416 (rank : 219)	NC score	0.208533 (rank : 313)
Query Neighborhood Hits	525	Target Neighborhood Hits	445	Shared Neighborhood Hits	221
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

IDD_HUMAN
θ value	0.0330416 (rank : 220)	NC score	0.145953 (rank : 504)
Query Neighborhood Hits	525	Target Neighborhood Hits	127	Shared Neighborhood Hits	62
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

ITB3_MOUSE
θ value	0.0330416 (rank : 221)	NC score	0.335458 (rank : 149)
Query Neighborhood Hits	525	Target Neighborhood Hits	319	Shared Neighborhood Hits	216
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

KLH10_HUMAN
θ value	0.0330416 (rank : 222)	NC score	0.185747 (rank : 366)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	68
SwissProt Accessions	Q6JEL2, Q6NW28, Q96MC0	Gene names	KLHL10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

KR106_HUMAN
θ value	0.0330416 (rank : 223)	NC score	0.319655 (rank : 171)
Query Neighborhood Hits	525	Target Neighborhood Hits	347	Shared Neighborhood Hits	183
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KREM2_HUMAN
θ value	0.0330416 (rank : 224)	NC score	0.224930 (rank : 289)
Query Neighborhood Hits	525	Target Neighborhood Hits	93	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

MLL4_HUMAN
θ value	0.0330416 (rank : 225)	NC score	0.042019 (rank : 862)
Query Neighborhood Hits	525	Target Neighborhood Hits	722	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PCSK5_MOUSE
θ value	0.0330416 (rank : 226)	NC score	0.309001 (rank : 183)
Query Neighborhood Hits	525	Target Neighborhood Hits	613	Shared Neighborhood Hits	246
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PGCA_HUMAN
θ value	0.0330416 (rank : 227)	NC score	0.208503 (rank : 314)
Query Neighborhood Hits	525	Target Neighborhood Hits	821	Shared Neighborhood Hits	204
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

CELR3_MOUSE
θ value	0.0431538 (rank : 228)	NC score	0.250209 (rank : 251)
Query Neighborhood Hits	525	Target Neighborhood Hits	687	Shared Neighborhood Hits	272
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

FATH_HUMAN
θ value	0.0431538 (rank : 229)	NC score	0.227942 (rank : 283)
Query Neighborhood Hits	525	Target Neighborhood Hits	570	Shared Neighborhood Hits	252
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

IDD_MOUSE
θ value	0.0431538 (rank : 230)	NC score	0.142946 (rank : 512)
Query Neighborhood Hits	525	Target Neighborhood Hits	151	Shared Neighborhood Hits	61
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

ITB8_HUMAN
θ value	0.0431538 (rank : 231)	NC score	0.300339 (rank : 194)
Query Neighborhood Hits	525	Target Neighborhood Hits	280	Shared Neighborhood Hits	211
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KBTB3_HUMAN
θ value	0.0431538 (rank : 232)	NC score	0.172813 (rank : 413)
Query Neighborhood Hits	525	Target Neighborhood Hits	176	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NAB2, Q86X38, Q96NK5	Gene names	KBTBD3, BKLHD3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

KBTB3_MOUSE
θ value	0.0431538 (rank : 233)	NC score	0.172774 (rank : 414)
Query Neighborhood Hits	525	Target Neighborhood Hits	176	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BHI4, Q8BNJ8	Gene names	Kbtbd3, Bklhd3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

KRA93_HUMAN
θ value	0.0431538 (rank : 234)	NC score	0.265747 (rank : 239)
Query Neighborhood Hits	525	Target Neighborhood Hits	203	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

LYAM3_MOUSE
θ value	0.0431538 (rank : 235)	NC score	0.291548 (rank : 207)
Query Neighborhood Hits	525	Target Neighborhood Hits	390	Shared Neighborhood Hits	225
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CLC6A_HUMAN
θ value	0.0563607 (rank : 236)	NC score	0.182402 (rank : 379)
Query Neighborhood Hits	525	Target Neighborhood Hits	119	Shared Neighborhood Hits	59
SwissProt Accessions	Q6EIG7	Gene names	CLEC6A, CLECSF10, DECTIN2
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated lectin 2) (DC-associated C-type lectin-2) (DECTIN-2).

DLL1_MOUSE
θ value	0.0563607 (rank : 237)	NC score	0.459182 (rank : 65)
Query Neighborhood Hits	525	Target Neighborhood Hits	456	Shared Neighborhood Hits	285
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

HGFA_MOUSE
θ value	0.0563607 (rank : 238)	NC score	0.160095 (rank : 458)
Query Neighborhood Hits	525	Target Neighborhood Hits	419	Shared Neighborhood Hits	201
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ITB6_MOUSE
θ value	0.0563607 (rank : 239)	NC score	0.358456 (rank : 125)
Query Neighborhood Hits	525	Target Neighborhood Hits	341	Shared Neighborhood Hits	232
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

KRA58_HUMAN
θ value	0.0563607 (rank : 240)	NC score	0.443093 (rank : 76)
Query Neighborhood Hits	525	Target Neighborhood Hits	324	Shared Neighborhood Hits	181
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KREM1_HUMAN
θ value	0.0563607 (rank : 241)	NC score	0.210716 (rank : 308)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

LTBP4_MOUSE
θ value	0.0563607 (rank : 242)	NC score	0.382788 (rank : 103)
Query Neighborhood Hits	525	Target Neighborhood Hits	607	Shared Neighborhood Hits	266
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

PROC_MOUSE
θ value	0.0563607 (rank : 243)	NC score	0.151654 (rank : 483)
Query Neighborhood Hits	525	Target Neighborhood Hits	426	Shared Neighborhood Hits	198
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

CREL1_HUMAN
θ value	0.0736092 (rank : 244)	NC score	0.389539 (rank : 97)
Query Neighborhood Hits	525	Target Neighborhood Hits	441	Shared Neighborhood Hits	212
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	0.0736092 (rank : 245)	NC score	0.375242 (rank : 110)
Query Neighborhood Hits	525	Target Neighborhood Hits	524	Shared Neighborhood Hits	221
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

HHIP_HUMAN
θ value	0.0736092 (rank : 246)	NC score	0.377179 (rank : 108)
Query Neighborhood Hits	525	Target Neighborhood Hits	249	Shared Neighborhood Hits	204
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KLDC1_HUMAN
θ value	0.0736092 (rank : 247)	NC score	0.192187 (rank : 349)
Query Neighborhood Hits	525	Target Neighborhood Hits	66	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N7A1, Q8WYI1	Gene names	KLHDC1
Domain Architecture
Description	Kelch domain-containing protein 1.

KLH18_HUMAN
θ value	0.0736092 (rank : 248)	NC score	0.199338 (rank : 331)
Query Neighborhood Hits	525	Target Neighborhood Hits	143	Shared Neighborhood Hits	72
SwissProt Accessions	O94889, Q8N125	Gene names	KLHL18, KIAA0795
Domain Architecture
Description	Kelch-like protein 18.

KLH23_HUMAN
θ value	0.0736092 (rank : 249)	NC score	0.185231 (rank : 370)
Query Neighborhood Hits	525	Target Neighborhood Hits	198	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NBE8, Q8N9B9, Q96FT8	Gene names	KLHL23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

LY75_HUMAN
θ value	0.0736092 (rank : 250)	NC score	0.157722 (rank : 469)
Query Neighborhood Hits	525	Target Neighborhood Hits	169	Shared Neighborhood Hits	66
SwissProt Accessions	O60449, O75913, Q7Z575, Q7Z577	Gene names	LY75, CD205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (gp200-MR6) (CD205 antigen).

PLXA4_HUMAN
θ value	0.0736092 (rank : 251)	NC score	0.072975 (rank : 709)
Query Neighborhood Hits	525	Target Neighborhood Hits	106	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA4_MOUSE
θ value	0.0736092 (rank : 252)	NC score	0.074678 (rank : 704)
Query Neighborhood Hits	525	Target Neighborhood Hits	109	Shared Neighborhood Hits	28
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

SEM4D_MOUSE
θ value	0.0736092 (rank : 253)	NC score	0.028629 (rank : 871)
Query Neighborhood Hits	525	Target Neighborhood Hits	143	Shared Neighborhood Hits	23
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SLIT3_HUMAN
θ value	0.0736092 (rank : 254)	NC score	0.305256 (rank : 190)
Query Neighborhood Hits	525	Target Neighborhood Hits	682	Shared Neighborhood Hits	256
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
θ value	0.0736092 (rank : 255)	NC score	0.307157 (rank : 187)
Query Neighborhood Hits	525	Target Neighborhood Hits	700	Shared Neighborhood Hits	265
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SSPO_MOUSE
θ value	0.0736092 (rank : 256)	NC score	0.248121 (rank : 258)
Query Neighborhood Hits	525	Target Neighborhood Hits	800	Shared Neighborhood Hits	282
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ASGR2_MOUSE
θ value	0.0961366 (rank : 257)	NC score	0.171553 (rank : 419)
Query Neighborhood Hits	525	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	P24721	Gene names	Asgr2, Asgr-2
Domain Architecture
Description	Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin 2) (MHL-2).

BKLH5_HUMAN
θ value	0.0961366 (rank : 258)	NC score	0.176506 (rank : 396)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	69
SwissProt Accessions	Q96NJ5, Q96PY7	Gene names	BKLHD5, KIAA1900
Domain Architecture
Description	BTB and kelch domain-containing protein 5.

CLC4A_MOUSE
θ value	0.0961366 (rank : 259)	NC score	0.189127 (rank : 358)
Query Neighborhood Hits	525	Target Neighborhood Hits	103	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QZ15, Q4VA33	Gene names	Clec4a, Clec4a2, Clecsf6, Dcir
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member A (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor).

CLC4F_MOUSE
θ value	0.0961366 (rank : 260)	NC score	0.152468 (rank : 480)
Query Neighborhood Hits	525	Target Neighborhood Hits	572	Shared Neighborhood Hits	72
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

CSPG2_HUMAN
θ value	0.0961366 (rank : 261)	NC score	0.330836 (rank : 158)
Query Neighborhood Hits	525	Target Neighborhood Hits	681	Shared Neighborhood Hits	267
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

DLL1_HUMAN
θ value	0.0961366 (rank : 262)	NC score	0.462715 (rank : 61)
Query Neighborhood Hits	525	Target Neighborhood Hits	455	Shared Neighborhood Hits	283
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DNER_MOUSE
θ value	0.0961366 (rank : 263)	NC score	0.452215 (rank : 70)
Query Neighborhood Hits	525	Target Neighborhood Hits	413	Shared Neighborhood Hits	259
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

FBN2_HUMAN
θ value	0.0961366 (rank : 264)	NC score	0.373277 (rank : 112)
Query Neighborhood Hits	525	Target Neighborhood Hits	560	Shared Neighborhood Hits	288
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FRAS1_HUMAN
θ value	0.0961366 (rank : 265)	NC score	0.293177 (rank : 205)
Query Neighborhood Hits	525	Target Neighborhood Hits	759	Shared Neighborhood Hits	234
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KRA54_HUMAN
θ value	0.0961366 (rank : 266)	NC score	0.416286 (rank : 86)
Query Neighborhood Hits	525	Target Neighborhood Hits	270	Shared Neighborhood Hits	154
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KREM2_MOUSE
θ value	0.0961366 (rank : 267)	NC score	0.207289 (rank : 316)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LTBP2_HUMAN
θ value	0.0961366 (rank : 268)	NC score	0.367103 (rank : 120)
Query Neighborhood Hits	525	Target Neighborhood Hits	552	Shared Neighborhood Hits	280
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	0.0961366 (rank : 269)	NC score	0.369353 (rank : 115)
Query Neighborhood Hits	525	Target Neighborhood Hits	617	Shared Neighborhood Hits	272
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LYAM1_MOUSE
θ value	0.0961366 (rank : 270)	NC score	0.296450 (rank : 199)
Query Neighborhood Hits	525	Target Neighborhood Hits	332	Shared Neighborhood Hits	209
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

SORL_HUMAN
θ value	0.0961366 (rank : 271)	NC score	0.201787 (rank : 329)
Query Neighborhood Hits	525	Target Neighborhood Hits	440	Shared Neighborhood Hits	180
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

CRUM1_HUMAN
θ value	0.125558 (rank : 272)	NC score	0.446225 (rank : 73)
Query Neighborhood Hits	525	Target Neighborhood Hits	457	Shared Neighborhood Hits	277
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DLK_MOUSE
θ value	0.125558 (rank : 273)	NC score	0.459484 (rank : 64)
Query Neighborhood Hits	525	Target Neighborhood Hits	374	Shared Neighborhood Hits	264
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

EGFL8_HUMAN
θ value	0.125558 (rank : 274)	NC score	0.321218 (rank : 169)
Query Neighborhood Hits	525	Target Neighborhood Hits	270	Shared Neighborhood Hits	179
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

FBN1_HUMAN
θ value	0.125558 (rank : 275)	NC score	0.375515 (rank : 109)
Query Neighborhood Hits	525	Target Neighborhood Hits	557	Shared Neighborhood Hits	284
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
θ value	0.125558 (rank : 276)	NC score	0.373580 (rank : 111)
Query Neighborhood Hits	525	Target Neighborhood Hits	549	Shared Neighborhood Hits	290
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

KBTB9_HUMAN
θ value	0.125558 (rank : 277)	NC score	0.177118 (rank : 395)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	68
SwissProt Accessions	Q96CT2, Q8N388, Q96BF0, Q96PW7	Gene names	KBTBD9, KIAA1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

KBTB9_MOUSE
θ value	0.125558 (rank : 278)	NC score	0.176460 (rank : 397)
Query Neighborhood Hits	525	Target Neighborhood Hits	197	Shared Neighborhood Hits	68
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

KLDC5_HUMAN
θ value	0.125558 (rank : 279)	NC score	0.190101 (rank : 356)
Query Neighborhood Hits	525	Target Neighborhood Hits	83	Shared Neighborhood Hits	65
SwissProt Accessions	Q9P2K6, Q2VPK1, Q8N334	Gene names	KLHDC5, KIAA1340
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 5.

KLH23_MOUSE
θ value	0.125558 (rank : 280)	NC score	0.181355 (rank : 382)
Query Neighborhood Hits	525	Target Neighborhood Hits	188	Shared Neighborhood Hits	72
SwissProt Accessions	Q6GQU2, Q8C840	Gene names	Klhl23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

KLH26_HUMAN
θ value	0.125558 (rank : 281)	NC score	0.177123 (rank : 394)
Query Neighborhood Hits	525	Target Neighborhood Hits	188	Shared Neighborhood Hits	66
SwissProt Accessions	Q53HC5, Q8TAP0, Q9NUX3	Gene names	KLHL26
Domain Architecture	No domain graphic available
Description	Kelch-like protein 26.

KRA59_HUMAN
θ value	0.125558 (rank : 282)	NC score	0.436231 (rank : 80)
Query Neighborhood Hits	525	Target Neighborhood Hits	310	Shared Neighborhood Hits	167
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LTB1L_MOUSE
θ value	0.125558 (rank : 283)	NC score	0.336501 (rank : 147)
Query Neighborhood Hits	525	Target Neighborhood Hits	514	Shared Neighborhood Hits	266
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	0.125558 (rank : 284)	NC score	0.337217 (rank : 146)
Query Neighborhood Hits	525	Target Neighborhood Hits	502	Shared Neighborhood Hits	259
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	0.125558 (rank : 285)	NC score	0.334781 (rank : 150)
Query Neighborhood Hits	525	Target Neighborhood Hits	479	Shared Neighborhood Hits	253
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MLL3_MOUSE
θ value	0.125558 (rank : 286)	NC score	0.048170 (rank : 858)
Query Neighborhood Hits	525	Target Neighborhood Hits	1399	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

C209B_MOUSE
θ value	0.163984 (rank : 287)	NC score	0.159626 (rank : 462)
Query Neighborhood Hits	525	Target Neighborhood Hits	140	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CJ91, Q8BGZ0, Q8BHK7, Q8CJ86, Q8CJ87, Q8CJ88, Q8CJ89, Q8CJ90, Q8CJ92, Q8CJ93, Q8CJ94, Q91ZW4, Q91ZX0, Q9D8V4	Gene names	Cd209b
Domain Architecture
Description	CD209 antigen-like protein B (DC-SIGN-related protein 1) (DC-SIGNR1) (OtB7).

CRUM1_MOUSE
θ value	0.163984 (rank : 288)	NC score	0.442705 (rank : 77)
Query Neighborhood Hits	525	Target Neighborhood Hits	444	Shared Neighborhood Hits	273
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CSPG2_MOUSE
θ value	0.163984 (rank : 289)	NC score	0.332026 (rank : 156)
Query Neighborhood Hits	525	Target Neighborhood Hits	711	Shared Neighborhood Hits	272
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

GP126_HUMAN
θ value	0.163984 (rank : 290)	NC score	0.178456 (rank : 392)
Query Neighborhood Hits	525	Target Neighborhood Hits	187	Shared Neighborhood Hits	58
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

KLDC5_MOUSE
θ value	0.163984 (rank : 291)	NC score	0.184410 (rank : 374)
Query Neighborhood Hits	525	Target Neighborhood Hits	86	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BFQ9, Q6ZPT4	Gene names	Klhdc5, Kiaa1340
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 5.

KLH22_HUMAN
θ value	0.163984 (rank : 292)	NC score	0.174569 (rank : 406)
Query Neighborhood Hits	525	Target Neighborhood Hits	198	Shared Neighborhood Hits	71
SwissProt Accessions	Q53GT1, Q96B68, Q96KC6	Gene names	KLHL22
Domain Architecture	No domain graphic available
Description	Kelch-like protein 22.

KRA55_HUMAN
θ value	0.163984 (rank : 293)	NC score	0.435851 (rank : 81)
Query Neighborhood Hits	525	Target Neighborhood Hits	257	Shared Neighborhood Hits	160
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

MLL3_HUMAN
θ value	0.163984 (rank : 294)	NC score	0.043898 (rank : 861)
Query Neighborhood Hits	525	Target Neighborhood Hits	1644	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TSP4_HUMAN
θ value	0.163984 (rank : 295)	NC score	0.306394 (rank : 188)
Query Neighborhood Hits	525	Target Neighborhood Hits	277	Shared Neighborhood Hits	194
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

CLC4E_HUMAN
θ value	0.21417 (rank : 296)	NC score	0.180142 (rank : 386)
Query Neighborhood Hits	525	Target Neighborhood Hits	104	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULY5	Gene names	CLEC4E, CLECSF9, MINCLE
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).

CLC9A_MOUSE
θ value	0.21417 (rank : 297)	NC score	0.164896 (rank : 446)
Query Neighborhood Hits	525	Target Neighborhood Hits	97	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BRU4	Gene names	Clec9a
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 9 member A.

HGFA_HUMAN
θ value	0.21417 (rank : 298)	NC score	0.165822 (rank : 442)
Query Neighborhood Hits	525	Target Neighborhood Hits	436	Shared Neighborhood Hits	207
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ITB3_HUMAN
θ value	0.21417 (rank : 299)	NC score	0.334693 (rank : 151)
Query Neighborhood Hits	525	Target Neighborhood Hits	325	Shared Neighborhood Hits	221
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

PLXA2_HUMAN
θ value	0.21417 (rank : 300)	NC score	0.072486 (rank : 715)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	O75051, Q6UX61, Q96GN9, Q9BRL1, Q9UIW1	Gene names	PLXNA2, KIAA0463, OCT
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Semaphorin receptor OCT).

TSP1_HUMAN
θ value	0.21417 (rank : 301)	NC score	0.208681 (rank : 312)
Query Neighborhood Hits	525	Target Neighborhood Hits	389	Shared Neighborhood Hits	185
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	0.21417 (rank : 302)	NC score	0.211679 (rank : 307)
Query Neighborhood Hits	525	Target Neighborhood Hits	396	Shared Neighborhood Hits	186
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

CDA7L_HUMAN
θ value	0.279714 (rank : 303)	NC score	0.046333 (rank : 860)
Query Neighborhood Hits	525	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	Q96GN5, Q6PIL4, Q86YT0, Q8IXN5, Q96C70, Q9H9A2, Q9NPV2	Gene names	CDCA7L, HR1, JPO2, R1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2).

CFC1_MOUSE
θ value	0.279714 (rank : 304)	NC score	0.243726 (rank : 263)
Query Neighborhood Hits	525	Target Neighborhood Hits	125	Shared Neighborhood Hits	119
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CORIN_MOUSE
θ value	0.279714 (rank : 305)	NC score	0.121311 (rank : 556)
Query Neighborhood Hits	525	Target Neighborhood Hits	451	Shared Neighborhood Hits	163
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

DLK_HUMAN
θ value	0.279714 (rank : 306)	NC score	0.466345 (rank : 57)
Query Neighborhood Hits	525	Target Neighborhood Hits	401	Shared Neighborhood Hits	273
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

HRX_HUMAN
θ value	0.279714 (rank : 307)	NC score	0.029869 (rank : 870)
Query Neighborhood Hits	525	Target Neighborhood Hits	825	Shared Neighborhood Hits	17
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IPP_HUMAN
θ value	0.279714 (rank : 308)	NC score	0.166769 (rank : 440)
Query Neighborhood Hits	525	Target Neighborhood Hits	186	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y573	Gene names	IPP
Domain Architecture
Description	Actin-binding protein IPP (MIPP protein).

KLH17_MOUSE
θ value	0.279714 (rank : 309)	NC score	0.170671 (rank : 423)
Query Neighborhood Hits	525	Target Neighborhood Hits	200	Shared Neighborhood Hits	66
SwissProt Accessions	Q6TDP3	Gene names	Klhl17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

KRA53_HUMAN
θ value	0.279714 (rank : 310)	NC score	0.454151 (rank : 68)
Query Neighborhood Hits	525	Target Neighborhood Hits	331	Shared Neighborhood Hits	185
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

PLXA1_HUMAN
θ value	0.279714 (rank : 311)	NC score	0.075718 (rank : 697)
Query Neighborhood Hits	525	Target Neighborhood Hits	108	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

PLXA2_MOUSE
θ value	0.279714 (rank : 312)	NC score	0.072123 (rank : 719)
Query Neighborhood Hits	525	Target Neighborhood Hits	97	Shared Neighborhood Hits	24
SwissProt Accessions	P70207, Q6NVE6, Q6PHN4, Q80TZ7, Q8R1I4	Gene names	Plxna2, Kiaa0463
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Plexin-2) (Plex 2).

PLXB2_HUMAN
θ value	0.279714 (rank : 313)	NC score	0.063824 (rank : 774)
Query Neighborhood Hits	525	Target Neighborhood Hits	94	Shared Neighborhood Hits	19
SwissProt Accessions	O15031, Q7KZU3, Q9BSU7	Gene names	PLXNB2, KIAA0315
Domain Architecture	No domain graphic available
Description	Plexin-B2 precursor (MM1).

CELR3_HUMAN
θ value	0.365318 (rank : 314)	NC score	0.252238 (rank : 248)
Query Neighborhood Hits	525	Target Neighborhood Hits	680	Shared Neighborhood Hits	267
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CFC1_HUMAN
θ value	0.365318 (rank : 315)	NC score	0.265452 (rank : 241)
Query Neighborhood Hits	525	Target Neighborhood Hits	148	Shared Neighborhood Hits	139
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

EGFL9_MOUSE
θ value	0.365318 (rank : 316)	NC score	0.440039 (rank : 78)
Query Neighborhood Hits	525	Target Neighborhood Hits	379	Shared Neighborhood Hits	254
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

IPP_MOUSE
θ value	0.365318 (rank : 317)	NC score	0.174046 (rank : 408)
Query Neighborhood Hits	525	Target Neighborhood Hits	188	Shared Neighborhood Hits	65
SwissProt Accessions	P28575	Gene names	Ipp, Mipp
Domain Architecture
Description	Actin-binding protein IPP (MIPP protein) (Murine IAP-promoted placenta-expressed protein).

ITB2_HUMAN
θ value	0.365318 (rank : 318)	NC score	0.327980 (rank : 160)
Query Neighborhood Hits	525	Target Neighborhood Hits	282	Shared Neighborhood Hits	199
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KLH17_HUMAN
θ value	0.365318 (rank : 319)	NC score	0.168258 (rank : 435)
Query Neighborhood Hits	525	Target Neighborhood Hits	201	Shared Neighborhood Hits	66
SwissProt Accessions	Q6TDP4	Gene names	KLHL17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

KRA11_HUMAN
θ value	0.365318 (rank : 320)	NC score	0.246419 (rank : 260)
Query Neighborhood Hits	525	Target Neighborhood Hits	155	Shared Neighborhood Hits	100
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

NRG2_MOUSE
θ value	0.365318 (rank : 321)	NC score	0.120321 (rank : 560)
Query Neighborhood Hits	525	Target Neighborhood Hits	392	Shared Neighborhood Hits	105
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

ODFP_HUMAN
θ value	0.365318 (rank : 322)	NC score	0.061699 (rank : 792)
Query Neighborhood Hits	525	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q14990	Gene names	ODF1, ODFP
Domain Architecture
Description	Outer dense fiber protein.

PLXA1_MOUSE
θ value	0.365318 (rank : 323)	NC score	0.073862 (rank : 706)
Query Neighborhood Hits	525	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	P70206, Q5DTR0	Gene names	Plxna1, KIAA4053
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Plexin-1) (Plex 1).

RELN_HUMAN
θ value	0.365318 (rank : 324)	NC score	0.180717 (rank : 385)
Query Neighborhood Hits	525	Target Neighborhood Hits	233	Shared Neighborhood Hits	160
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

TSP4_MOUSE
θ value	0.365318 (rank : 325)	NC score	0.308042 (rank : 186)
Query Neighborhood Hits	525	Target Neighborhood Hits	276	Shared Neighborhood Hits	201
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

VASN_MOUSE
θ value	0.365318 (rank : 326)	NC score	0.084757 (rank : 657)
Query Neighborhood Hits	525	Target Neighborhood Hits	426	Shared Neighborhood Hits	124
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ASGR2_HUMAN
θ value	0.47712 (rank : 327)	NC score	0.158371 (rank : 465)
Query Neighborhood Hits	525	Target Neighborhood Hits	121	Shared Neighborhood Hits	58
SwissProt Accessions	P07307, O00448, Q03969	Gene names	ASGR2
Domain Architecture
Description	Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin H2).

EDIL3_HUMAN
θ value	0.47712 (rank : 328)	NC score	0.327863 (rank : 161)
Query Neighborhood Hits	525	Target Neighborhood Hits	292	Shared Neighborhood Hits	204
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

KLDC1_MOUSE
θ value	0.47712 (rank : 329)	NC score	0.190840 (rank : 354)
Query Neighborhood Hits	525	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YG3	Gene names	Klhdc1
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 1.

KRA45_HUMAN
θ value	0.47712 (rank : 330)	NC score	0.231985 (rank : 280)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

SEM4D_HUMAN
θ value	0.47712 (rank : 331)	NC score	0.025007 (rank : 876)
Query Neighborhood Hits	525	Target Neighborhood Hits	139	Shared Neighborhood Hits	21
SwissProt Accessions	Q92854, Q7Z5S4	Gene names	SEMA4D, CD100
Domain Architecture
Description	Semaphorin-4D precursor (Leukocyte activation antigen CD100) (BB18) (A8) (GR3).

BMPER_HUMAN
θ value	0.62314 (rank : 332)	NC score	0.109593 (rank : 581)
Query Neighborhood Hits	525	Target Neighborhood Hits	175	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CALI_HUMAN
θ value	0.62314 (rank : 333)	NC score	0.164386 (rank : 448)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	64
SwissProt Accessions	Q13939, Q9BXG7	Gene names	CCIN
Domain Architecture
Description	Calicin.

EDIL3_MOUSE
θ value	0.62314 (rank : 334)	NC score	0.350078 (rank : 135)
Query Neighborhood Hits	525	Target Neighborhood Hits	317	Shared Neighborhood Hits	222
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

KLDC4_HUMAN
θ value	0.62314 (rank : 335)	NC score	0.190246 (rank : 355)
Query Neighborhood Hits	525	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TBB5, Q96F29, Q9BVN3	Gene names	KLHDC4
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 4.

KLH22_MOUSE
θ value	0.62314 (rank : 336)	NC score	0.169745 (rank : 429)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	67
SwissProt Accessions	Q99JN2, Q8BT13	Gene names	Klhl22, Kelchl
Domain Architecture	No domain graphic available
Description	Kelch-like protein 22.

KPCT_HUMAN
θ value	0.62314 (rank : 337)	NC score	-0.003468 (rank : 909)
Query Neighborhood Hits	525	Target Neighborhood Hits	897	Shared Neighborhood Hits	23
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_MOUSE
θ value	0.62314 (rank : 338)	NC score	-0.003779 (rank : 910)
Query Neighborhood Hits	525	Target Neighborhood Hits	895	Shared Neighborhood Hits	21
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KREM1_MOUSE
θ value	0.62314 (rank : 339)	NC score	0.193801 (rank : 344)
Query Neighborhood Hits	525	Target Neighborhood Hits	92	Shared Neighborhood Hits	60
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

MFGM_MOUSE
θ value	0.62314 (rank : 340)	NC score	0.275315 (rank : 227)
Query Neighborhood Hits	525	Target Neighborhood Hits	233	Shared Neighborhood Hits	176
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MT1H_HUMAN
θ value	0.62314 (rank : 341)	NC score	0.146562 (rank : 500)
Query Neighborhood Hits	525	Target Neighborhood Hits	78	Shared Neighborhood Hits	50
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

PCDA6_HUMAN
θ value	0.62314 (rank : 342)	NC score	0.024388 (rank : 877)
Query Neighborhood Hits	525	Target Neighborhood Hits	187	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UN73, O75283, Q9NRT8	Gene names	PCDHA6
Domain Architecture
Description	Protocadherin alpha 6 precursor (PCDH-alpha6).

PGCA_MOUSE
θ value	0.62314 (rank : 343)	NC score	0.141553 (rank : 517)
Query Neighborhood Hits	525	Target Neighborhood Hits	643	Shared Neighborhood Hits	79
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

SORL_MOUSE
θ value	0.62314 (rank : 344)	NC score	0.212725 (rank : 306)
Query Neighborhood Hits	525	Target Neighborhood Hits	439	Shared Neighborhood Hits	186
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TDGF1_HUMAN
θ value	0.62314 (rank : 345)	NC score	0.203540 (rank : 325)
Query Neighborhood Hits	525	Target Neighborhood Hits	132	Shared Neighborhood Hits	121
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TNR9_MOUSE
θ value	0.62314 (rank : 346)	NC score	0.136166 (rank : 531)
Query Neighborhood Hits	525	Target Neighborhood Hits	137	Shared Neighborhood Hits	69
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

CLC4D_MOUSE
θ value	0.813845 (rank : 347)	NC score	0.168118 (rank : 436)
Query Neighborhood Hits	525	Target Neighborhood Hits	104	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z2H6, Q8C212	Gene names	Clec4d, Clecsf8, Mcl
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member D (C-type lectin superfamily member 8) (Macrophage-restricted C-type lectin).

EGFL9_HUMAN
θ value	0.813845 (rank : 348)	NC score	0.443639 (rank : 75)
Query Neighborhood Hits	525	Target Neighborhood Hits	365	Shared Neighborhood Hits	252
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

FA9_HUMAN
θ value	0.813845 (rank : 349)	NC score	0.140043 (rank : 524)
Query Neighborhood Hits	525	Target Neighborhood Hits	421	Shared Neighborhood Hits	190
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

HMCN1_HUMAN
θ value	0.813845 (rank : 350)	NC score	0.179480 (rank : 387)
Query Neighborhood Hits	525	Target Neighborhood Hits	983	Shared Neighborhood Hits	224
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KLHL6_MOUSE
θ value	0.813845 (rank : 351)	NC score	0.169416 (rank : 431)
Query Neighborhood Hits	525	Target Neighborhood Hits	186	Shared Neighborhood Hits	63
SwissProt Accessions	Q6V595	Gene names	Klhl6
Domain Architecture	No domain graphic available
Description	Kelch-like protein 6.

KR104_HUMAN
θ value	0.813845 (rank : 352)	NC score	0.318587 (rank : 173)
Query Neighborhood Hits	525	Target Neighborhood Hits	313	Shared Neighborhood Hits	162
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KRA56_HUMAN
θ value	0.813845 (rank : 353)	NC score	0.404632 (rank : 93)
Query Neighborhood Hits	525	Target Neighborhood Hits	207	Shared Neighborhood Hits	132
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

MUC2_HUMAN
θ value	0.813845 (rank : 354)	NC score	0.112610 (rank : 572)
Query Neighborhood Hits	525	Target Neighborhood Hits	906	Shared Neighborhood Hits	148
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PCDA5_HUMAN
θ value	0.813845 (rank : 355)	NC score	0.024046 (rank : 878)
Query Neighborhood Hits	525	Target Neighborhood Hits	217	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

PLXB3_HUMAN
θ value	0.813845 (rank : 356)	NC score	0.066261 (rank : 755)
Query Neighborhood Hits	525	Target Neighborhood Hits	106	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

PLXC1_MOUSE
θ value	0.813845 (rank : 357)	NC score	0.069723 (rank : 734)
Query Neighborhood Hits	525	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QZC2, Q8CGW1	Gene names	Plxnc1, Vespr
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

RELN_MOUSE
θ value	0.813845 (rank : 358)	NC score	0.181067 (rank : 383)
Query Neighborhood Hits	525	Target Neighborhood Hits	235	Shared Neighborhood Hits	164
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

SPY1_HUMAN
θ value	0.813845 (rank : 359)	NC score	0.047871 (rank : 859)
Query Neighborhood Hits	525	Target Neighborhood Hits	64	Shared Neighborhood Hits	39
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

VASN_HUMAN
θ value	0.813845 (rank : 360)	NC score	0.093363 (rank : 625)
Query Neighborhood Hits	525	Target Neighborhood Hits	449	Shared Neighborhood Hits	131
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ADA23_MOUSE
θ value	1.06291 (rank : 361)	NC score	0.086739 (rank : 643)
Query Neighborhood Hits	525	Target Neighborhood Hits	245	Shared Neighborhood Hits	145
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA33_MOUSE
θ value	1.06291 (rank : 362)	NC score	0.070118 (rank : 733)
Query Neighborhood Hits	525	Target Neighborhood Hits	231	Shared Neighborhood Hits	131
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

BTBD5_HUMAN
θ value	1.06291 (rank : 363)	NC score	0.171715 (rank : 418)
Query Neighborhood Hits	525	Target Neighborhood Hits	190	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NXS3	Gene names	BTBD5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

CT127_HUMAN
θ value	1.06291 (rank : 364)	NC score	0.154464 (rank : 476)
Query Neighborhood Hits	525	Target Neighborhood Hits	67	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

DCBD2_HUMAN
θ value	1.06291 (rank : 365)	NC score	0.205577 (rank : 319)
Query Neighborhood Hits	525	Target Neighborhood Hits	118	Shared Neighborhood Hits	57
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

EPHB6_HUMAN
θ value	1.06291 (rank : 366)	NC score	0.028013 (rank : 872)
Query Neighborhood Hits	525	Target Neighborhood Hits	912	Shared Neighborhood Hits	78
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

KBTBB_MOUSE
θ value	1.06291 (rank : 367)	NC score	0.159922 (rank : 460)
Query Neighborhood Hits	525	Target Neighborhood Hits	184	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BNW9	Gene names	Kbtbd11, Kiaa0711
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 11.

KLH26_MOUSE
θ value	1.06291 (rank : 368)	NC score	0.170363 (rank : 424)
Query Neighborhood Hits	525	Target Neighborhood Hits	190	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BGY4, Q8CIG6, Q8R153	Gene names	Klhl26
Domain Architecture	No domain graphic available
Description	Kelch-like protein 26.

KLHL3_HUMAN
θ value	1.06291 (rank : 369)	NC score	0.169821 (rank : 428)
Query Neighborhood Hits	525	Target Neighborhood Hits	187	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UH77, Q9UH75, Q9UH76, Q9ULU0, Q9Y6V6	Gene names	KLHL3, KIAA1129
Domain Architecture
Description	Kelch-like protein 3.

KLRBB_MOUSE
θ value	1.06291 (rank : 370)	NC score	0.135503 (rank : 533)
Query Neighborhood Hits	525	Target Neighborhood Hits	105	Shared Neighborhood Hits	59
SwissProt Accessions	P27812	Gene names	Klrb1b, Ly55-b, Ly55b
Domain Architecture
Description	Natural killer cell surface protein P1-34 (NKR-P1 34).

KR107_HUMAN
θ value	1.06291 (rank : 371)	NC score	0.319490 (rank : 172)
Query Neighborhood Hits	525	Target Neighborhood Hits	330	Shared Neighborhood Hits	181
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA92_HUMAN
θ value	1.06291 (rank : 372)	NC score	0.232645 (rank : 279)
Query Neighborhood Hits	525	Target Neighborhood Hits	198	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

NELL1_HUMAN
θ value	1.06291 (rank : 373)	NC score	0.370772 (rank : 113)
Query Neighborhood Hits	525	Target Neighborhood Hits	451	Shared Neighborhood Hits	268
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

PGH2_MOUSE
θ value	1.06291 (rank : 374)	NC score	0.109037 (rank : 583)
Query Neighborhood Hits	525	Target Neighborhood Hits	113	Shared Neighborhood Hits	85
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PLXB3_MOUSE
θ value	1.06291 (rank : 375)	NC score	0.065293 (rank : 763)
Query Neighborhood Hits	525	Target Neighborhood Hits	94	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

PLXD1_HUMAN
θ value	1.06291 (rank : 376)	NC score	0.068652 (rank : 739)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

SCUB3_MOUSE
θ value	1.06291 (rank : 377)	NC score	0.368084 (rank : 118)
Query Neighborhood Hits	525	Target Neighborhood Hits	442	Shared Neighborhood Hits	258
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SMDF_HUMAN
θ value	1.06291 (rank : 378)	NC score	0.140002 (rank : 525)
Query Neighborhood Hits	525	Target Neighborhood Hits	117	Shared Neighborhood Hits	69
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

ADA23_HUMAN
θ value	1.38821 (rank : 379)	NC score	0.087199 (rank : 640)
Query Neighborhood Hits	525	Target Neighborhood Hits	235	Shared Neighborhood Hits	140
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

BTBD5_MOUSE
θ value	1.38821 (rank : 380)	NC score	0.169846 (rank : 427)
Query Neighborhood Hits	525	Target Neighborhood Hits	189	Shared Neighborhood Hits	67
SwissProt Accessions	Q9CR40, Q9CYV0	Gene names	Btbd5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

CLC5A_HUMAN
θ value	1.38821 (rank : 381)	NC score	0.127686 (rank : 543)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NY25, Q9UKQ0	Gene names	CLEC5A, CLECSF5, MDL1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 5 member A (C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin) (MDL-1).

EPHB4_HUMAN
θ value	1.38821 (rank : 382)	NC score	0.039421 (rank : 863)
Query Neighborhood Hits	525	Target Neighborhood Hits	1056	Shared Neighborhood Hits	117
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

FA10_HUMAN
θ value	1.38821 (rank : 383)	NC score	0.140501 (rank : 522)
Query Neighborhood Hits	525	Target Neighborhood Hits	431	Shared Neighborhood Hits	186
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

KBTB6_HUMAN
θ value	1.38821 (rank : 384)	NC score	0.151635 (rank : 484)
Query Neighborhood Hits	525	Target Neighborhood Hits	175	Shared Neighborhood Hits	59
SwissProt Accessions	Q86V97, Q8N8L0, Q8NDM5, Q96MP6	Gene names	KBTBD6
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 6.

KBTB7_HUMAN
θ value	1.38821 (rank : 385)	NC score	0.152252 (rank : 481)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WVZ9, Q8NB99, Q9H0I6	Gene names	KBTBD7
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 7.

KLHL2_HUMAN
θ value	1.38821 (rank : 386)	NC score	0.167587 (rank : 437)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	65
SwissProt Accessions	O95198, Q8N484, Q8TBH5	Gene names	KLHL2
Domain Architecture
Description	Kelch-like protein 2 (Actin-binding protein Mayven).

KLHL2_MOUSE
θ value	1.38821 (rank : 387)	NC score	0.167556 (rank : 438)
Query Neighborhood Hits	525	Target Neighborhood Hits	190	Shared Neighborhood Hits	65
SwissProt Accessions	Q8JZP3, Q8CCU0, Q8R3U4	Gene names	Klhl2
Domain Architecture	No domain graphic available
Description	Kelch-like protein 2.

LRP3_HUMAN
θ value	1.38821 (rank : 388)	NC score	0.265722 (rank : 240)
Query Neighborhood Hits	525	Target Neighborhood Hits	280	Shared Neighborhood Hits	130
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LYAM3_HUMAN
θ value	1.38821 (rank : 389)	NC score	0.280565 (rank : 220)
Query Neighborhood Hits	525	Target Neighborhood Hits	378	Shared Neighborhood Hits	222
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MT1L_HUMAN
θ value	1.38821 (rank : 390)	NC score	0.113313 (rank : 569)
Query Neighborhood Hits	525	Target Neighborhood Hits	73	Shared Neighborhood Hits	42
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

NRX1A_HUMAN
θ value	1.38821 (rank : 391)	NC score	0.209967 (rank : 310)
Query Neighborhood Hits	525	Target Neighborhood Hits	170	Shared Neighborhood Hits	117
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX3A_HUMAN
θ value	1.38821 (rank : 392)	NC score	0.198854 (rank : 335)
Query Neighborhood Hits	525	Target Neighborhood Hits	164	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PCDA7_HUMAN
θ value	1.38821 (rank : 393)	NC score	0.023369 (rank : 879)
Query Neighborhood Hits	525	Target Neighborhood Hits	221	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UN72, O75282	Gene names	PCDHA7
Domain Architecture
Description	Protocadherin alpha 7 precursor (PCDH-alpha7).

PROS_HUMAN
θ value	1.38821 (rank : 394)	NC score	0.323044 (rank : 164)
Query Neighborhood Hits	525	Target Neighborhood Hits	340	Shared Neighborhood Hits	221
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	1.38821 (rank : 395)	NC score	0.311832 (rank : 180)
Query Neighborhood Hits	525	Target Neighborhood Hits	330	Shared Neighborhood Hits	222
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

THYG_MOUSE
θ value	1.38821 (rank : 396)	NC score	0.038002 (rank : 865)
Query Neighborhood Hits	525	Target Neighborhood Hits	161	Shared Neighborhood Hits	53
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TNR23_MOUSE
θ value	1.38821 (rank : 397)	NC score	0.134613 (rank : 536)
Query Neighborhood Hits	525	Target Neighborhood Hits	114	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

DCBD2_MOUSE
θ value	1.81305 (rank : 398)	NC score	0.197793 (rank : 337)
Query Neighborhood Hits	525	Target Neighborhood Hits	113	Shared Neighborhood Hits	58
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

ESM1_HUMAN
θ value	1.81305 (rank : 399)	NC score	0.205556 (rank : 320)
Query Neighborhood Hits	525	Target Neighborhood Hits	110	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

KLHL6_HUMAN
θ value	1.81305 (rank : 400)	NC score	0.165099 (rank : 444)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WZ60, Q8N5I1, Q8N892	Gene names	KLHL6
Domain Architecture
Description	Kelch-like protein 6.

KR10B_HUMAN
θ value	1.81305 (rank : 401)	NC score	0.235136 (rank : 273)
Query Neighborhood Hits	525	Target Neighborhood Hits	269	Shared Neighborhood Hits	140
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR412_HUMAN
θ value	1.81305 (rank : 402)	NC score	0.192493 (rank : 347)
Query Neighborhood Hits	525	Target Neighborhood Hits	178	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR511_HUMAN
θ value	1.81305 (rank : 403)	NC score	0.382525 (rank : 104)
Query Neighborhood Hits	525	Target Neighborhood Hits	231	Shared Neighborhood Hits	134
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

LCMT2_MOUSE
θ value	1.81305 (rank : 404)	NC score	0.053375 (rank : 839)
Query Neighborhood Hits	525	Target Neighborhood Hits	33	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BYR1, Q3T9F7, Q6A048, Q8BIG6	Gene names	Lcmt2, Kiaa0547
Domain Architecture	No domain graphic available
Description	Leucine carboxyl methyltransferase 2 (EC 2.1.1.-) (p21WAF1/CIP1 promoter-interacting protein).

MT1E_HUMAN
θ value	1.81305 (rank : 405)	NC score	0.109480 (rank : 582)
Query Neighborhood Hits	525	Target Neighborhood Hits	75	Shared Neighborhood Hits	52
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT1X_HUMAN
θ value	1.81305 (rank : 406)	NC score	0.163829 (rank : 450)
Query Neighborhood Hits	525	Target Neighborhood Hits	76	Shared Neighborhood Hits	51
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

NID2_HUMAN
θ value	1.81305 (rank : 407)	NC score	0.290669 (rank : 209)
Query Neighborhood Hits	525	Target Neighborhood Hits	456	Shared Neighborhood Hits	214
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NRX1A_MOUSE
θ value	1.81305 (rank : 408)	NC score	0.207992 (rank : 315)
Query Neighborhood Hits	525	Target Neighborhood Hits	164	Shared Neighborhood Hits	116
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

SCUB3_HUMAN
θ value	1.81305 (rank : 409)	NC score	0.367880 (rank : 119)
Query Neighborhood Hits	525	Target Neighborhood Hits	428	Shared Neighborhood Hits	251
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TDGF1_MOUSE
θ value	1.81305 (rank : 410)	NC score	0.239532 (rank : 268)
Query Neighborhood Hits	525	Target Neighborhood Hits	146	Shared Neighborhood Hits	134
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TFF2_HUMAN
θ value	1.81305 (rank : 411)	NC score	0.027243 (rank : 873)
Query Neighborhood Hits	525	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q03403, Q15854	Gene names	TFF2, SML1
Domain Architecture
Description	Trefoil factor 2 precursor (Spasmolytic polypeptide) (SP) (Spasmolysin).

TNR4_HUMAN
θ value	1.81305 (rank : 412)	NC score	0.158181 (rank : 467)
Query Neighborhood Hits	525	Target Neighborhood Hits	152	Shared Neighborhood Hits	62
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

BRCA2_HUMAN
θ value	2.36792 (rank : 413)	NC score	0.015792 (rank : 892)
Query Neighborhood Hits	525	Target Neighborhood Hits	202	Shared Neighborhood Hits	11
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

COMP_MOUSE
θ value	2.36792 (rank : 414)	NC score	0.308361 (rank : 184)
Query Neighborhood Hits	525	Target Neighborhood Hits	290	Shared Neighborhood Hits	201
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

FA12_HUMAN
θ value	2.36792 (rank : 415)	NC score	0.150010 (rank : 487)
Query Neighborhood Hits	525	Target Neighborhood Hits	425	Shared Neighborhood Hits	198
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FBLN2_MOUSE
θ value	2.36792 (rank : 416)	NC score	0.293104 (rank : 206)
Query Neighborhood Hits	525	Target Neighborhood Hits	505	Shared Neighborhood Hits	219
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

KRA44_HUMAN
θ value	2.36792 (rank : 417)	NC score	0.218393 (rank : 298)
Query Neighborhood Hits	525	Target Neighborhood Hits	162	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA57_HUMAN
θ value	2.36792 (rank : 418)	NC score	0.415719 (rank : 88)
Query Neighborhood Hits	525	Target Neighborhood Hits	269	Shared Neighborhood Hits	162
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

LRP2_HUMAN
θ value	2.36792 (rank : 419)	NC score	0.290716 (rank : 208)
Query Neighborhood Hits	525	Target Neighborhood Hits	573	Shared Neighborhood Hits	290
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

MASP1_HUMAN
θ value	2.36792 (rank : 420)	NC score	0.163015 (rank : 453)
Query Neighborhood Hits	525	Target Neighborhood Hits	369	Shared Neighborhood Hits	125
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

NKG2A_HUMAN
θ value	2.36792 (rank : 421)	NC score	0.115797 (rank : 567)
Query Neighborhood Hits	525	Target Neighborhood Hits	94	Shared Neighborhood Hits	52
SwissProt Accessions	P26715	Gene names	KLRC1, NKG2A
Domain Architecture
Description	NKG2-A/NKG2-B type II integral membrane protein (NKG2-A/B-activating NK receptor) (NK cell receptor A) (CD159a antigen).

NRX2A_HUMAN
θ value	2.36792 (rank : 422)	NC score	0.185599 (rank : 368)
Query Neighborhood Hits	525	Target Neighborhood Hits	614	Shared Neighborhood Hits	128
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

PLXB1_HUMAN
θ value	2.36792 (rank : 423)	NC score	0.058684 (rank : 813)
Query Neighborhood Hits	525	Target Neighborhood Hits	360	Shared Neighborhood Hits	28
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

TSP2_HUMAN
θ value	2.36792 (rank : 424)	NC score	0.178513 (rank : 391)
Query Neighborhood Hits	525	Target Neighborhood Hits	359	Shared Neighborhood Hits	177
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ADA15_MOUSE
θ value	3.0926 (rank : 425)	NC score	0.092726 (rank : 626)
Query Neighborhood Hits	525	Target Neighborhood Hits	324	Shared Neighborhood Hits	166
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA19_MOUSE
θ value	3.0926 (rank : 426)	NC score	0.080610 (rank : 678)
Query Neighborhood Hits	525	Target Neighborhood Hits	315	Shared Neighborhood Hits	159
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA22_MOUSE
θ value	3.0926 (rank : 427)	NC score	0.078890 (rank : 687)
Query Neighborhood Hits	525	Target Neighborhood Hits	225	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

CDCA7_MOUSE
θ value	3.0926 (rank : 428)	NC score	0.035947 (rank : 867)
Query Neighborhood Hits	525	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D0M2, Q3TIS1, Q3U511, Q6NZE5, Q8C1A0	Gene names	Cdca7
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated protein 7.

CLC4F_HUMAN
θ value	3.0926 (rank : 429)	NC score	0.123922 (rank : 550)
Query Neighborhood Hits	525	Target Neighborhood Hits	513	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

CNTP4_HUMAN
θ value	3.0926 (rank : 430)	NC score	0.173915 (rank : 409)
Query Neighborhood Hits	525	Target Neighborhood Hits	187	Shared Neighborhood Hits	116
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CSPG3_MOUSE
θ value	3.0926 (rank : 431)	NC score	0.340893 (rank : 141)
Query Neighborhood Hits	525	Target Neighborhood Hits	657	Shared Neighborhood Hits	269
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

EPHB4_MOUSE
θ value	3.0926 (rank : 432)	NC score	0.025668 (rank : 875)
Query Neighborhood Hits	525	Target Neighborhood Hits	1013	Shared Neighborhood Hits	101
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

KRA52_HUMAN
θ value	3.0926 (rank : 433)	NC score	0.369279 (rank : 116)
Query Neighborhood Hits	525	Target Neighborhood Hits	236	Shared Neighborhood Hits	141
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LRP4_MOUSE
θ value	3.0926 (rank : 434)	NC score	0.226224 (rank : 287)
Query Neighborhood Hits	525	Target Neighborhood Hits	351	Shared Neighborhood Hits	193
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LTB1L_HUMAN
θ value	3.0926 (rank : 435)	NC score	0.332906 (rank : 153)
Query Neighborhood Hits	525	Target Neighborhood Hits	553	Shared Neighborhood Hits	260
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MT1B_HUMAN
θ value	3.0926 (rank : 436)	NC score	0.130946 (rank : 541)
Query Neighborhood Hits	525	Target Neighborhood Hits	87	Shared Neighborhood Hits	55
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MUC5B_HUMAN
θ value	3.0926 (rank : 437)	NC score	0.175839 (rank : 401)
Query Neighborhood Hits	525	Target Neighborhood Hits	1020	Shared Neighborhood Hits	217
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PCDA8_HUMAN
θ value	3.0926 (rank : 438)	NC score	0.021802 (rank : 882)
Query Neighborhood Hits	525	Target Neighborhood Hits	187	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5H6, O75281	Gene names	PCDHA8
Domain Architecture
Description	Protocadherin alpha 8 precursor (PCDH-alpha8).

PROC_HUMAN
θ value	3.0926 (rank : 439)	NC score	0.129131 (rank : 542)
Query Neighborhood Hits	525	Target Neighborhood Hits	406	Shared Neighborhood Hits	187
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

REG4_HUMAN
θ value	3.0926 (rank : 440)	NC score	0.146047 (rank : 503)
Query Neighborhood Hits	525	Target Neighborhood Hits	105	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYZ8, Q8NER6, Q8NER7	Gene names	REG4, GISP, RELP
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 4 precursor (Reg IV) (REG-like protein) (Gastrointestinal secretory protein).

RNF38_HUMAN
θ value	3.0926 (rank : 441)	NC score	0.012118 (rank : 901)
Query Neighborhood Hits	525	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF38_MOUSE
θ value	3.0926 (rank : 442)	NC score	0.012142 (rank : 899)
Query Neighborhood Hits	525	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

ADA22_HUMAN
θ value	4.03905 (rank : 443)	NC score	0.069485 (rank : 737)
Query Neighborhood Hits	525	Target Neighborhood Hits	211	Shared Neighborhood Hits	120
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

CNTP4_MOUSE
θ value	4.03905 (rank : 444)	NC score	0.172262 (rank : 416)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	130
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

DGKH_HUMAN
θ value	4.03905 (rank : 445)	NC score	0.007864 (rank : 905)
Query Neighborhood Hits	525	Target Neighborhood Hits	255	Shared Neighborhood Hits	17
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DPOLN_MOUSE
θ value	4.03905 (rank : 446)	NC score	0.010937 (rank : 902)
Query Neighborhood Hits	525	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TQ07, Q3V0L3	Gene names	Poln
Domain Architecture	No domain graphic available
Description	DNA polymerase nu (EC 2.7.7.7).

FA10_MOUSE
θ value	4.03905 (rank : 447)	NC score	0.140124 (rank : 523)
Query Neighborhood Hits	525	Target Neighborhood Hits	435	Shared Neighborhood Hits	194
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FAT2_HUMAN
θ value	4.03905 (rank : 448)	NC score	0.156700 (rank : 471)
Query Neighborhood Hits	525	Target Neighborhood Hits	507	Shared Neighborhood Hits	206
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

GAS6_HUMAN
θ value	4.03905 (rank : 449)	NC score	0.312135 (rank : 178)
Query Neighborhood Hits	525	Target Neighborhood Hits	348	Shared Neighborhood Hits	218
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	4.03905 (rank : 450)	NC score	0.308198 (rank : 185)
Query Neighborhood Hits	525	Target Neighborhood Hits	343	Shared Neighborhood Hits	224
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

K1H8_HUMAN
θ value	4.03905 (rank : 451)	NC score	-0.000451 (rank : 908)
Query Neighborhood Hits	525	Target Neighborhood Hits	394	Shared Neighborhood Hits	10
SwissProt Accessions	O76015	Gene names	KRTHA8, HHA8, HKA8
Domain Architecture
Description	Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8).

KLHL4_HUMAN
θ value	4.03905 (rank : 452)	NC score	0.175225 (rank : 403)
Query Neighborhood Hits	525	Target Neighborhood Hits	212	Shared Neighborhood Hits	69
SwissProt Accessions	Q9C0H6, Q9Y3J5	Gene names	KLHL4, KIAA1687
Domain Architecture
Description	Kelch-like protein 4.

KPCB_HUMAN
θ value	4.03905 (rank : 453)	NC score	-0.005380 (rank : 912)
Query Neighborhood Hits	525	Target Neighborhood Hits	1121	Shared Neighborhood Hits	22
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	4.03905 (rank : 454)	NC score	-0.005372 (rank : 911)
Query Neighborhood Hits	525	Target Neighborhood Hits	1117	Shared Neighborhood Hits	22
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

MASP2_HUMAN
θ value	4.03905 (rank : 455)	NC score	0.159996 (rank : 459)
Query Neighborhood Hits	525	Target Neighborhood Hits	364	Shared Neighborhood Hits	125
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MT1A_HUMAN
θ value	4.03905 (rank : 456)	NC score	0.147457 (rank : 495)
Query Neighborhood Hits	525	Target Neighborhood Hits	74	Shared Neighborhood Hits	53
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT3_HUMAN
θ value	4.03905 (rank : 457)	NC score	0.200998 (rank : 330)
Query Neighborhood Hits	525	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

NRG2_HUMAN
θ value	4.03905 (rank : 458)	NC score	0.091574 (rank : 628)
Query Neighborhood Hits	525	Target Neighborhood Hits	419	Shared Neighborhood Hits	91
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

PCDAA_HUMAN
θ value	4.03905 (rank : 459)	NC score	0.021485 (rank : 884)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5I2, O75280, Q9NRU2	Gene names	PCDHA10
Domain Architecture
Description	Protocadherin alpha 10 precursor (PCDH-alpha10).

PROZ_MOUSE
θ value	4.03905 (rank : 460)	NC score	0.242515 (rank : 265)
Query Neighborhood Hits	525	Target Neighborhood Hits	410	Shared Neighborhood Hits	195
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PSCA_MOUSE
θ value	4.03905 (rank : 461)	NC score	0.027114 (rank : 874)
Query Neighborhood Hits	525	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P57096	Gene names	Psca
Domain Architecture	No domain graphic available
Description	Prostate stem cell antigen precursor.

TICN1_HUMAN
θ value	4.03905 (rank : 462)	NC score	0.019374 (rank : 888)
Query Neighborhood Hits	525	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_MOUSE
θ value	4.03905 (rank : 463)	NC score	0.018913 (rank : 889)
Query Neighborhood Hits	525	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

UBP3_MOUSE
θ value	4.03905 (rank : 464)	NC score	0.002586 (rank : 907)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

ZAN_MOUSE
θ value	4.03905 (rank : 465)	NC score	0.322718 (rank : 166)
Query Neighborhood Hits	525	Target Neighborhood Hits	808	Shared Neighborhood Hits	298
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ADA11_HUMAN
θ value	5.27518 (rank : 466)	NC score	0.096466 (rank : 612)
Query Neighborhood Hits	525	Target Neighborhood Hits	259	Shared Neighborhood Hits	155
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	5.27518 (rank : 467)	NC score	0.096716 (rank : 610)
Query Neighborhood Hits	525	Target Neighborhood Hits	263	Shared Neighborhood Hits	156
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

C163B_HUMAN
θ value	5.27518 (rank : 468)	NC score	0.032329 (rank : 869)
Query Neighborhood Hits	525	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

DGKQ_HUMAN
θ value	5.27518 (rank : 469)	NC score	0.012755 (rank : 898)
Query Neighborhood Hits	525	Target Neighborhood Hits	131	Shared Neighborhood Hits	20
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

FA45B_HUMAN
θ value	5.27518 (rank : 470)	NC score	0.013038 (rank : 896)
Query Neighborhood Hits	525	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NSW5, Q9NZ36	Gene names	FAM45B
Domain Architecture	No domain graphic available
Description	Protein FAM45B.

IGF1R_HUMAN
θ value	5.27518 (rank : 471)	NC score	0.015895 (rank : 891)
Query Neighborhood Hits	525	Target Neighborhood Hits	977	Shared Neighborhood Hits	94
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KBTBB_HUMAN
θ value	5.27518 (rank : 472)	NC score	0.152874 (rank : 477)
Query Neighborhood Hits	525	Target Neighborhood Hits	195	Shared Neighborhood Hits	65
SwissProt Accessions	O94819	Gene names	KBTBD11, KIAA0711, KLHDC7C
Domain Architecture	No domain graphic available
Description	Kelch repeat and BTB domain-containing protein 11 (Kelch domain- containing protein 7B).

KLD8A_HUMAN
θ value	5.27518 (rank : 473)	NC score	0.169369 (rank : 432)
Query Neighborhood Hits	525	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IYD2, Q9NVG5	Gene names	KLHDC8A
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8A.

KLDC2_MOUSE
θ value	5.27518 (rank : 474)	NC score	0.146217 (rank : 502)
Query Neighborhood Hits	525	Target Neighborhood Hits	44	Shared Neighborhood Hits	40
SwissProt Accessions	Q4G5Y1, Q99JY2, Q9D784	Gene names	Klhdc2
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 2 (Endothelial differentiation inhibitory protein TNG).

LIPB_HUMAN
θ value	5.27518 (rank : 475)	NC score	0.016444 (rank : 890)
Query Neighborhood Hits	525	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y234	Gene names	LIPT1
Domain Architecture
Description	Lipoyltransferase 1, mitochondrial precursor (EC 6.-.-.-) (Lipoate- protein ligase) (Lipoate biosynthesis protein) (Lipoyl ligase).

MGAT3_HUMAN
θ value	5.27518 (rank : 476)	NC score	0.037422 (rank : 866)
Query Neighborhood Hits	525	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	Q09327, Q6IC49, Q9UH32	Gene names	MGAT3, GGNT3
Domain Architecture
Description	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase III) (N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III).

MGAT3_MOUSE
θ value	5.27518 (rank : 477)	NC score	0.035233 (rank : 868)
Query Neighborhood Hits	525	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	Q10470, P70386	Gene names	Mgat3
Domain Architecture
Description	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase III) (N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III).

NELL2_HUMAN
θ value	5.27518 (rank : 478)	NC score	0.352282 (rank : 131)
Query Neighborhood Hits	525	Target Neighborhood Hits	449	Shared Neighborhood Hits	265
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

PCDA3_HUMAN
θ value	5.27518 (rank : 479)	NC score	0.021840 (rank : 881)
Query Neighborhood Hits	525	Target Neighborhood Hits	203	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5H8, O75286	Gene names	PCDHA3
Domain Architecture
Description	Protocadherin alpha 3 precursor (PCDH-alpha3).

TDGF2_HUMAN
θ value	5.27518 (rank : 480)	NC score	0.185587 (rank : 369)
Query Neighborhood Hits	525	Target Neighborhood Hits	131	Shared Neighborhood Hits	116
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TPA_MOUSE
θ value	5.27518 (rank : 481)	NC score	0.094178 (rank : 623)
Query Neighborhood Hits	525	Target Neighborhood Hits	335	Shared Neighborhood Hits	154
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TSP2_MOUSE
θ value	5.27518 (rank : 482)	NC score	0.183430 (rank : 377)
Query Neighborhood Hits	525	Target Neighborhood Hits	352	Shared Neighborhood Hits	179
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ZNFX1_HUMAN
θ value	5.27518 (rank : 483)	NC score	0.070367 (rank : 729)
Query Neighborhood Hits	525	Target Neighborhood Hits	308	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ADA32_HUMAN
θ value	6.88961 (rank : 484)	NC score	0.061721 (rank : 791)
Query Neighborhood Hits	525	Target Neighborhood Hits	216	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ATS1_MOUSE
θ value	6.88961 (rank : 485)	NC score	0.012835 (rank : 897)
Query Neighborhood Hits	525	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

CRIM1_HUMAN
θ value	6.88961 (rank : 486)	NC score	0.287734 (rank : 212)
Query Neighborhood Hits	525	Target Neighborhood Hits	362	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

ENPP1_HUMAN
θ value	6.88961 (rank : 487)	NC score	0.010017 (rank : 904)
Query Neighborhood Hits	525	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	P22413, Q5T9R6, Q9NPZ3, Q9P1P6, Q9UP61, Q9Y6K3	Gene names	ENPP1, NPPS, PC1, PDNP1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

EPHA1_HUMAN
θ value	6.88961 (rank : 488)	NC score	0.020141 (rank : 887)
Query Neighborhood Hits	525	Target Neighborhood Hits	997	Shared Neighborhood Hits	94
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

KLDC2_HUMAN
θ value	6.88961 (rank : 489)	NC score	0.155231 (rank : 473)
Query Neighborhood Hits	525	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y2U9, Q6IAF0	Gene names	KLHDC2, HCA33
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 2 (Hepatocellular carcinoma-associated antigen 33) (Host cell factor homolog LCP).

KR413_HUMAN
θ value	6.88961 (rank : 490)	NC score	0.105582 (rank : 591)
Query Neighborhood Hits	525	Target Neighborhood Hits	112	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KRA42_HUMAN
θ value	6.88961 (rank : 491)	NC score	0.143121 (rank : 511)
Query Neighborhood Hits	525	Target Neighborhood Hits	149	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA94_HUMAN
θ value	6.88961 (rank : 492)	NC score	0.240772 (rank : 266)
Query Neighborhood Hits	525	Target Neighborhood Hits	204	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

LRP4_HUMAN
θ value	6.88961 (rank : 493)	NC score	0.225147 (rank : 288)
Query Neighborhood Hits	525	Target Neighborhood Hits	355	Shared Neighborhood Hits	192
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

NELL2_MOUSE
θ value	6.88961 (rank : 494)	NC score	0.350689 (rank : 134)
Query Neighborhood Hits	525	Target Neighborhood Hits	436	Shared Neighborhood Hits	262
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NKG2C_HUMAN
θ value	6.88961 (rank : 495)	NC score	0.109632 (rank : 580)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	P26717, O43802, Q9NR42	Gene names	KLRC2, NKG2C
Domain Architecture
Description	NKG2-C type II integral membrane protein (NKG2-C-activating NK receptor) (NK cell receptor C) (CD159c antigen).

ODFP_MOUSE
θ value	6.88961 (rank : 496)	NC score	0.095536 (rank : 614)
Query Neighborhood Hits	525	Target Neighborhood Hits	75	Shared Neighborhood Hits	41
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PCDAD_HUMAN
θ value	6.88961 (rank : 497)	NC score	0.021787 (rank : 883)
Query Neighborhood Hits	525	Target Neighborhood Hits	197	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5I0, O75277	Gene names	PCDHA13
Domain Architecture
Description	Protocadherin alpha 13 precursor (PCDH-alpha13).

PCSK5_HUMAN
θ value	6.88961 (rank : 498)	NC score	0.179147 (rank : 390)
Query Neighborhood Hits	525	Target Neighborhood Hits	291	Shared Neighborhood Hits	153
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PHF10_HUMAN
θ value	6.88961 (rank : 499)	NC score	0.015772 (rank : 894)
Query Neighborhood Hits	525	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHLD1_HUMAN
θ value	6.88961 (rank : 500)	NC score	0.007153 (rank : 906)
Query Neighborhood Hits	525	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	P80108, Q15128	Gene names	GPLD1, PIGPLD1
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 1 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

SUSD1_HUMAN
θ value	6.88961 (rank : 501)	NC score	0.270174 (rank : 234)
Query Neighborhood Hits	525	Target Neighborhood Hits	285	Shared Neighborhood Hits	169
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TPA_HUMAN
θ value	6.88961 (rank : 502)	NC score	0.092093 (rank : 627)
Query Neighborhood Hits	525	Target Neighborhood Hits	324	Shared Neighborhood Hits	152
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

UROK_MOUSE
θ value	6.88961 (rank : 503)	NC score	0.064054 (rank : 772)
Query Neighborhood Hits	525	Target Neighborhood Hits	273	Shared Neighborhood Hits	115
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

VLDLR_MOUSE
θ value	6.88961 (rank : 504)	NC score	0.246149 (rank : 261)
Query Neighborhood Hits	525	Target Neighborhood Hits	360	Shared Neighborhood Hits	200
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ADA19_HUMAN
θ value	8.99809 (rank : 505)	NC score	0.071277 (rank : 724)
Query Neighborhood Hits	525	Target Neighborhood Hits	381	Shared Neighborhood Hits	147
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ATS1_HUMAN
θ value	8.99809 (rank : 506)	NC score	0.012125 (rank : 900)
Query Neighborhood Hits	525	Target Neighborhood Hits	159	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

CDA7L_MOUSE
θ value	8.99809 (rank : 507)	NC score	0.022259 (rank : 880)
Query Neighborhood Hits	525	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q922M5	Gene names	Cdca7l
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Transcription factor RAM2).

ERBB2_MOUSE
θ value	8.99809 (rank : 508)	NC score	0.013086 (rank : 895)
Query Neighborhood Hits	525	Target Neighborhood Hits	918	Shared Neighborhood Hits	72
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

FREM1_HUMAN
θ value	8.99809 (rank : 509)	NC score	0.071625 (rank : 722)
Query Neighborhood Hits	525	Target Neighborhood Hits	170	Shared Neighborhood Hits	56
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

ITB2_MOUSE
θ value	8.99809 (rank : 510)	NC score	0.339369 (rank : 145)
Query Neighborhood Hits	525	Target Neighborhood Hits	326	Shared Neighborhood Hits	220
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

K1333_HUMAN
θ value	8.99809 (rank : 511)	NC score	0.020333 (rank : 886)
Query Neighborhood Hits	525	Target Neighborhood Hits	50	Shared Neighborhood Hits	10
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

KPCG_HUMAN
θ value	8.99809 (rank : 512)	NC score	-0.005985 (rank : 913)
Query Neighborhood Hits	525	Target Neighborhood Hits	1126	Shared Neighborhood Hits	22
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
θ value	8.99809 (rank : 513)	NC score	-0.006046 (rank : 914)
Query Neighborhood Hits	525	Target Neighborhood Hits	1123	Shared Neighborhood Hits	22
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KR102_HUMAN
θ value	8.99809 (rank : 514)	NC score	0.246996 (rank : 259)
Query Neighborhood Hits	525	Target Neighborhood Hits	264	Shared Neighborhood Hits	143
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KRA13_HUMAN
θ value	8.99809 (rank : 515)	NC score	0.226904 (rank : 285)
Query Neighborhood Hits	525	Target Neighborhood Hits	144	Shared Neighborhood Hits	92
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA51_HUMAN
θ value	8.99809 (rank : 516)	NC score	0.450213 (rank : 71)
Query Neighborhood Hits	525	Target Neighborhood Hits	288	Shared Neighborhood Hits	170
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA99_HUMAN
θ value	8.99809 (rank : 517)	NC score	0.203850 (rank : 324)
Query Neighborhood Hits	525	Target Neighborhood Hits	173	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LRP10_HUMAN
θ value	8.99809 (rank : 518)	NC score	0.196997 (rank : 339)
Query Neighborhood Hits	525	Target Neighborhood Hits	197	Shared Neighborhood Hits	93
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

MASP2_MOUSE
θ value	8.99809 (rank : 519)	NC score	0.159252 (rank : 463)
Query Neighborhood Hits	525	Target Neighborhood Hits	382	Shared Neighborhood Hits	133
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

NRG1_HUMAN
θ value	8.99809 (rank : 520)	NC score	0.104371 (rank : 593)
Query Neighborhood Hits	525	Target Neighborhood Hits	285	Shared Neighborhood Hits	86
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

PCDA4_HUMAN
θ value	8.99809 (rank : 521)	NC score	0.021457 (rank : 885)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UN74, O75285	Gene names	PCDHA4
Domain Architecture
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

PROP_MOUSE
θ value	8.99809 (rank : 522)	NC score	0.038344 (rank : 864)
Query Neighborhood Hits	525	Target Neighborhood Hits	165	Shared Neighborhood Hits	38
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PXDC2_HUMAN
θ value	8.99809 (rank : 523)	NC score	0.015785 (rank : 893)
Query Neighborhood Hits	525	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UX71, Q96E59, Q96PD9, Q96SU9	Gene names	PLXDC2, TEM7R
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 2 precursor (Tumor endothelial marker 7-related protein).

ZCHC4_MOUSE
θ value	8.99809 (rank : 524)	NC score	0.010228 (rank : 903)
Query Neighborhood Hits	525	Target Neighborhood Hits	63	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKW4, Q3UTX6, Q9D2I1	Gene names	Zcchc4
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 4.

ZNFX1_MOUSE
θ value	8.99809 (rank : 525)	NC score	0.065980 (rank : 759)
Query Neighborhood Hits	525	Target Neighborhood Hits	407	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ABTB1_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.072974 (rank : 710)
Query Neighborhood Hits	525	Target Neighborhood Hits	325	Shared Neighborhood Hits	58
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ABTB1_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.066649 (rank : 752)
Query Neighborhood Hits	525	Target Neighborhood Hits	349	Shared Neighborhood Hits	58
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ABTB2_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.061801 (rank : 788)
Query Neighborhood Hits	525	Target Neighborhood Hits	391	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ABTB2_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.057680 (rank : 820)
Query Neighborhood Hits	525	Target Neighborhood Hits	414	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ADA10_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.064453 (rank : 770)
Query Neighborhood Hits	525	Target Neighborhood Hits	189	Shared Neighborhood Hits	94
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.061738 (rank : 790)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	99
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA15_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.085776 (rank : 653)
Query Neighborhood Hits	525	Target Neighborhood Hits	288	Shared Neighborhood Hits	160
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA17_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.057406 (rank : 822)
Query Neighborhood Hits	525	Target Neighborhood Hits	223	Shared Neighborhood Hits	97
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA18_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.063761 (rank : 775)
Query Neighborhood Hits	525	Target Neighborhood Hits	227	Shared Neighborhood Hits	134
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA24_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.053307 (rank : 840)
Query Neighborhood Hits	525	Target Neighborhood Hits	230	Shared Neighborhood Hits	134
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA25_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.051577 (rank : 848)
Query Neighborhood Hits	525	Target Neighborhood Hits	213	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA28_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.057928 (rank : 817)
Query Neighborhood Hits	525	Target Neighborhood Hits	244	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA28_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.058996 (rank : 810)
Query Neighborhood Hits	525	Target Neighborhood Hits	241	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA33_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.067848 (rank : 744)
Query Neighborhood Hits	525	Target Neighborhood Hits	264	Shared Neighborhood Hits	138
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.064753 (rank : 769)
Query Neighborhood Hits	525	Target Neighborhood Hits	209	Shared Neighborhood Hits	121
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM7_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.059017 (rank : 809)
Query Neighborhood Hits	525	Target Neighborhood Hits	221	Shared Neighborhood Hits	126
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM8_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.085959 (rank : 650)
Query Neighborhood Hits	525	Target Neighborhood Hits	327	Shared Neighborhood Hits	165
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
θ value	θ > 10 (rank : 543)	NC score	0.084387 (rank : 658)
Query Neighborhood Hits	525	Target Neighborhood Hits	326	Shared Neighborhood Hits	163
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.066132 (rank : 756)
Query Neighborhood Hits	525	Target Neighborhood Hits	243	Shared Neighborhood Hits	142
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM9_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.071067 (rank : 726)
Query Neighborhood Hits	525	Target Neighborhood Hits	325	Shared Neighborhood Hits	157
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADM1A_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.055310 (rank : 830)
Query Neighborhood Hits	525	Target Neighborhood Hits	230	Shared Neighborhood Hits	128
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ANFY1_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.053296 (rank : 841)
Query Neighborhood Hits	525	Target Neighborhood Hits	480	Shared Neighborhood Hits	52
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.053549 (rank : 838)
Query Neighborhood Hits	525	Target Neighborhood Hits	480	Shared Neighborhood Hits	53
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

APOH_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.065772 (rank : 760)
Query Neighborhood Hits	525	Target Neighborhood Hits	75	Shared Neighborhood Hits	17
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

APOH_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.067791 (rank : 746)
Query Neighborhood Hits	525	Target Neighborhood Hits	74	Shared Neighborhood Hits	20
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

APR3_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.070140 (rank : 732)
Query Neighborhood Hits	525	Target Neighborhood Hits	50	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

APR3_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.080796 (rank : 675)
Query Neighborhood Hits	525	Target Neighborhood Hits	61	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ASTL_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.110825 (rank : 575)
Query Neighborhood Hits	525	Target Neighborhood Hits	252	Shared Neighborhood Hits	16
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTL_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.109731 (rank : 579)
Query Neighborhood Hits	525	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTN_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.059676 (rank : 803)
Query Neighborhood Hits	525	Target Neighborhood Hits	105	Shared Neighborhood Hits	50
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.059937 (rank : 802)
Query Neighborhood Hits	525	Target Neighborhood Hits	98	Shared Neighborhood Hits	48
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

BACH1_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.081319 (rank : 673)
Query Neighborhood Hits	525	Target Neighborhood Hits	289	Shared Neighborhood Hits	55
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

BACH1_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.080615 (rank : 677)
Query Neighborhood Hits	525	Target Neighborhood Hits	289	Shared Neighborhood Hits	55
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

BACH2_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.085823 (rank : 652)
Query Neighborhood Hits	525	Target Neighborhood Hits	234	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BACH2_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.080270 (rank : 680)
Query Neighborhood Hits	525	Target Neighborhood Hits	248	Shared Neighborhood Hits	56
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BMPER_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.106946 (rank : 587)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	107
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BTBD1_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.096634 (rank : 611)
Query Neighborhood Hits	525	Target Neighborhood Hits	127	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H0C5, Q9BX71, Q9NWN4	Gene names	BTBD1, C15orf1
Domain Architecture
Description	BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A- transactivated protein 8) (NS5ATP8).

BTBD1_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.090611 (rank : 633)
Query Neighborhood Hits	525	Target Neighborhood Hits	114	Shared Neighborhood Hits	51
SwissProt Accessions	P58544, Q8BTZ0, Q8K0J0	Gene names	Btbd1, Gsrp
Domain Architecture
Description	BTB/POZ domain-containing protein 1 (Glucose signal repressing protein).

BTBD2_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.101192 (rank : 598)
Query Neighborhood Hits	525	Target Neighborhood Hits	161	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BX70, O60418, O75248, Q7Z5W0, Q96SX8, Q9NPS1, Q9NX81	Gene names	BTBD2
Domain Architecture
Description	BTB/POZ domain-containing protein 2.

BTBD3_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.094904 (rank : 615)
Query Neighborhood Hits	525	Target Neighborhood Hits	127	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2F9	Gene names	BTBD3, KIAA0952
Domain Architecture
Description	BTB/POZ domain-containing protein 3.

BTBD3_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.094754 (rank : 618)
Query Neighborhood Hits	525	Target Neighborhood Hits	124	Shared Neighborhood Hits	54
SwissProt Accessions	P58545	Gene names	Btbd3
Domain Architecture
Description	BTB/POZ domain-containing protein 3.

BTBD6_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.096792 (rank : 609)
Query Neighborhood Hits	525	Target Neighborhood Hits	121	Shared Neighborhood Hits	54
SwissProt Accessions	Q96KE9, Q8IVQ7, Q9BR94	Gene names	BTBD6, BDPL
Domain Architecture
Description	BTB/POZ domain-containing protein 6 (Lens BTB domain protein).

BTBD6_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.096312 (rank : 613)
Query Neighborhood Hits	525	Target Neighborhood Hits	125	Shared Neighborhood Hits	54
SwissProt Accessions	Q8K2J9	Gene names	Btbd6
Domain Architecture
Description	BTB/POZ domain-containing protein 6.

BTBD8_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.100021 (rank : 602)
Query Neighborhood Hits	525	Target Neighborhood Hits	146	Shared Neighborhood Hits	50
SwissProt Accessions	Q5XKL5, Q6V9S5	Gene names	BTBD8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 8.

BTBD9_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.117218 (rank : 564)
Query Neighborhood Hits	525	Target Neighborhood Hits	163	Shared Neighborhood Hits	56
SwissProt Accessions	Q96Q07, Q96M00	Gene names	BTBD9, KIAA1880
Domain Architecture
Description	BTB/POZ domain-containing protein 9.

BTBD9_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.116342 (rank : 565)
Query Neighborhood Hits	525	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C726	Gene names	Btbd9
Domain Architecture
Description	BTB/POZ domain-containing protein 9.

BTC_MOUSE
θ value	θ > 10 (rank : 572)	NC score	0.051316 (rank : 849)
Query Neighborhood Hits	525	Target Neighborhood Hits	67	Shared Neighborhood Hits	44
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

C1QR1_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.293903 (rank : 203)
Query Neighborhood Hits	525	Target Neighborhood Hits	493	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.295090 (rank : 202)
Query Neighborhood Hits	525	Target Neighborhood Hits	342	Shared Neighborhood Hits	215
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1RA_MOUSE
θ value	θ > 10 (rank : 575)	NC score	0.163325 (rank : 451)
Query Neighborhood Hits	525	Target Neighborhood Hits	379	Shared Neighborhood Hits	140
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.161379 (rank : 455)
Query Neighborhood Hits	525	Target Neighborhood Hits	380	Shared Neighborhood Hits	140
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.158694 (rank : 464)
Query Neighborhood Hits	525	Target Neighborhood Hits	364	Shared Neighborhood Hits	128
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.148280 (rank : 491)
Query Neighborhood Hits	525	Target Neighborhood Hits	359	Shared Neighborhood Hits	131
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

C209C_MOUSE
θ value	θ > 10 (rank : 579)	NC score	0.142617 (rank : 513)
Query Neighborhood Hits	525	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	Q91ZW9	Gene names	Cd209c
Domain Architecture
Description	CD209 antigen-like protein C (DC-SIGN-related protein 2) (DC-SIGNR2).

C209D_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.161028 (rank : 457)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	58
SwissProt Accessions	Q91ZW8, Q8VIK4	Gene names	Cd209d
Domain Architecture
Description	CD209 antigen-like protein D (DC-SIGN-related protein 3) (DC-SIGNR3).

C4BB_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.090874 (rank : 632)
Query Neighborhood Hits	525	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

C4BP_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.070293 (rank : 731)
Query Neighborhood Hits	525	Target Neighborhood Hits	92	Shared Neighborhood Hits	27
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

C4BP_MOUSE
θ value	θ > 10 (rank : 583)	NC score	0.073525 (rank : 708)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	23
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

CD209_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.132226 (rank : 539)
Query Neighborhood Hits	525	Target Neighborhood Hits	244	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NNX6, Q96QP7, Q96QP8, Q96QP9, Q96QQ0, Q96QQ1, Q96QQ2, Q96QQ3, Q96QQ4, Q96QQ5, Q96QQ6, Q96QQ7, Q96QQ8	Gene names	CD209, CLEC4L
Domain Architecture
Description	CD209 antigen (Dendritic cell-specific ICAM-3-grabbing nonintegrin 1) (DC-SIGN1) (DC-SIGN) (C-type lectin domain family 4 member L).

CD248_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.216706 (rank : 302)
Query Neighborhood Hits	525	Target Neighborhood Hits	679	Shared Neighborhood Hits	190
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.218181 (rank : 300)
Query Neighborhood Hits	525	Target Neighborhood Hits	578	Shared Neighborhood Hits	178
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD302_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.076758 (rank : 691)
Query Neighborhood Hits	525	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IX05, Q15009	Gene names	CD302, CLEC13A, DCL1, KIAA0022
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (C- type lectin BIMLEC) (Type I transmembrane C-type lectin receptor DCL- 1).

CD302_MOUSE
θ value	θ > 10 (rank : 588)	NC score	0.089684 (rank : 634)
Query Neighborhood Hits	525	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DCG2, Q78KD8, Q9D0X7	Gene names	Cd302, Clec13a
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (Type I transmembrane C-type lectin receptor DCL-1).

CD320_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.109930 (rank : 576)
Query Neighborhood Hits	525	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD69_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.135989 (rank : 532)
Query Neighborhood Hits	525	Target Neighborhood Hits	92	Shared Neighborhood Hits	52
SwissProt Accessions	P37217	Gene names	Cd69
Domain Architecture	No domain graphic available
Description	Early activation antigen CD69.

CD72_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.099960 (rank : 603)
Query Neighborhood Hits	525	Target Neighborhood Hits	345	Shared Neighborhood Hits	53
SwissProt Accessions	P21854	Gene names	CD72
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2).

CD72_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.053233 (rank : 842)
Query Neighborhood Hits	525	Target Neighborhood Hits	262	Shared Neighborhood Hits	41
SwissProt Accessions	P21855, Q64225	Gene names	Cd72, Ly-32, Lyb-2
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2) (Antigen Ly-32).

CD97_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.226608 (rank : 286)
Query Neighborhood Hits	525	Target Neighborhood Hits	353	Shared Neighborhood Hits	188
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.172372 (rank : 415)
Query Neighborhood Hits	525	Target Neighborhood Hits	295	Shared Neighborhood Hits	147
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CFAB_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.060611 (rank : 798)
Query Neighborhood Hits	525	Target Neighborhood Hits	251	Shared Neighborhood Hits	41
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.062172 (rank : 785)
Query Neighborhood Hits	525	Target Neighborhood Hits	262	Shared Neighborhood Hits	43
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAH_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.068548 (rank : 741)
Query Neighborhood Hits	525	Target Neighborhood Hits	101	Shared Neighborhood Hits	29
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CFAH_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.066474 (rank : 754)
Query Neighborhood Hits	525	Target Neighborhood Hits	112	Shared Neighborhood Hits	27
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

CFAI_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.057155 (rank : 824)
Query Neighborhood Hits	525	Target Neighborhood Hits	289	Shared Neighborhood Hits	68
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_MOUSE
θ value	θ > 10 (rank : 600)	NC score	0.057266 (rank : 823)
Query Neighborhood Hits	525	Target Neighborhood Hits	290	Shared Neighborhood Hits	71
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CHODL_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.086612 (rank : 645)
Query Neighborhood Hits	525	Target Neighborhood Hits	81	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H9P2, Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3	Gene names	CHODL, C21orf68
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

CHODL_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.082329 (rank : 670)
Query Neighborhood Hits	525	Target Neighborhood Hits	80	Shared Neighborhood Hits	40
SwissProt Accessions	Q9CXM0, Q8VI31	Gene names	Chodl
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

CHRD_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.055060 (rank : 832)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.056684 (rank : 825)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CLC14_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.075241 (rank : 702)
Query Neighborhood Hits	525	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.076556 (rank : 692)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CLC2B_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.125768 (rank : 547)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	Q92478, Q8IZE9, Q9BS74, Q9UQB4	Gene names	CLEC2B, AICL, CLECSF2, IFNRG1
Domain Architecture
Description	C-type lectin domain family 2 member B (C-type lectin superfamily member 2) (Activation-induced C-type lectin) (IFN-alpha2b-inducing- related protein 1) (C-type lectin domain family 2 member B).

CLC3A_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.086191 (rank : 649)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	46
SwissProt Accessions	O75596, Q6UXF5	Gene names	CLEC3A, CLECSF1
Domain Architecture
Description	C-type lectin domain family 3 member A precursor (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin).

CLC3A_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.085269 (rank : 655)
Query Neighborhood Hits	525	Target Neighborhood Hits	95	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EPW4	Gene names	Clec3a, Clecsf1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 3 member A precursor (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin).

CLC4G_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.133635 (rank : 537)
Query Neighborhood Hits	525	Target Neighborhood Hits	141	Shared Neighborhood Hits	55
SwissProt Accessions	Q6UXB4	Gene names	CLEC4G
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member G.

CLC4G_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.139980 (rank : 526)
Query Neighborhood Hits	525	Target Neighborhood Hits	155	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BNX1, Q5I0T7, Q8R188	Gene names	Clec4g
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member G.

CLC4M_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.131834 (rank : 540)
Query Neighborhood Hits	525	Target Neighborhood Hits	291	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H2X3, Q69F40, Q969M4, Q96QP3, Q96QP4, Q96QP5, Q96QP6, Q9BXS3, Q9H2Q9, Q9H8F0, Q9Y2A8	Gene names	CLEC4M, CD209L, CD209L1
Domain Architecture
Description	C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM- 3-grabbing nonintegrin) (L-SIGN) (CD299 antigen).

CLC5A_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.120885 (rank : 559)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R007, Q3UV97, Q8BL24	Gene names	Clec5a, Clecsf5, Mdl1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 5 member A (C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin protein) (MDL-1).

CNTP1_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.143872 (rank : 508)
Query Neighborhood Hits	525	Target Neighborhood Hits	196	Shared Neighborhood Hits	110
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.142505 (rank : 514)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	105
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP2_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.173900 (rank : 410)
Query Neighborhood Hits	525	Target Neighborhood Hits	199	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.174452 (rank : 407)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	130
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.154699 (rank : 475)
Query Neighborhood Hits	525	Target Neighborhood Hits	195	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CO2_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.062406 (rank : 782)
Query Neighborhood Hits	525	Target Neighborhood Hits	258	Shared Neighborhood Hits	42
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 620)	NC score	0.055945 (rank : 828)
Query Neighborhood Hits	525	Target Neighborhood Hits	250	Shared Neighborhood Hits	41
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO6_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.146976 (rank : 498)
Query Neighborhood Hits	525	Target Neighborhood Hits	331	Shared Neighborhood Hits	152
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.122102 (rank : 555)
Query Neighborhood Hits	525	Target Neighborhood Hits	278	Shared Neighborhood Hits	127
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.069539 (rank : 736)
Query Neighborhood Hits	525	Target Neighborhood Hits	200	Shared Neighborhood Hits	91
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.063219 (rank : 778)
Query Neighborhood Hits	525	Target Neighborhood Hits	182	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.072362 (rank : 716)
Query Neighborhood Hits	525	Target Neighborhood Hits	199	Shared Neighborhood Hits	87
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.094378 (rank : 622)
Query Neighborhood Hits	525	Target Neighborhood Hits	224	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO9_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.079345 (rank : 684)
Query Neighborhood Hits	525	Target Neighborhood Hits	147	Shared Neighborhood Hits	80
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.082827 (rank : 666)
Query Neighborhood Hits	525	Target Neighborhood Hits	153	Shared Neighborhood Hits	87
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

COMP_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.286659 (rank : 214)
Query Neighborhood Hits	525	Target Neighborhood Hits	258	Shared Neighborhood Hits	181
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CORIN_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.125944 (rank : 546)
Query Neighborhood Hits	525	Target Neighborhood Hits	453	Shared Neighborhood Hits	174
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CR1_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.083632 (rank : 661)
Query Neighborhood Hits	525	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CR2_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.084338 (rank : 659)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	28
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

CR2_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.084055 (rank : 660)
Query Neighborhood Hits	525	Target Neighborhood Hits	101	Shared Neighborhood Hits	29
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

CRAC1_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.070576 (rank : 728)
Query Neighborhood Hits	525	Target Neighborhood Hits	111	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.071911 (rank : 720)
Query Neighborhood Hits	525	Target Neighborhood Hits	112	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRRY_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.069696 (rank : 735)
Query Neighborhood Hits	525	Target Neighborhood Hits	84	Shared Neighborhood Hits	22
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

CS1A_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.147413 (rank : 496)
Query Neighborhood Hits	525	Target Neighborhood Hits	360	Shared Neighborhood Hits	123
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.147718 (rank : 493)
Query Neighborhood Hits	525	Target Neighborhood Hits	361	Shared Neighborhood Hits	124
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CSPG4_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.065304 (rank : 761)
Query Neighborhood Hits	525	Target Neighborhood Hits	112	Shared Neighborhood Hits	33
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.063944 (rank : 773)
Query Neighborhood Hits	525	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

DAF1_MOUSE
θ value	θ > 10 (rank : 641)	NC score	0.066868 (rank : 751)
Query Neighborhood Hits	525	Target Neighborhood Hits	204	Shared Neighborhood Hits	30
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DAF2_MOUSE
θ value	θ > 10 (rank : 642)	NC score	0.064818 (rank : 768)
Query Neighborhood Hits	525	Target Neighborhood Hits	114	Shared Neighborhood Hits	25
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

DAF_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.063340 (rank : 777)
Query Neighborhood Hits	525	Target Neighborhood Hits	97	Shared Neighborhood Hits	23
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

DCBD1_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.161453 (rank : 454)
Query Neighborhood Hits	525	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD1_MOUSE
θ value	θ > 10 (rank : 645)	NC score	0.171165 (rank : 421)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DKK3_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.051603 (rank : 847)
Query Neighborhood Hits	525	Target Neighborhood Hits	83	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

EGF_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.248799 (rank : 254)
Query Neighborhood Hits	525	Target Neighborhood Hits	343	Shared Neighborhood Hits	213
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 648)	NC score	0.279339 (rank : 222)
Query Neighborhood Hits	525	Target Neighborhood Hits	358	Shared Neighborhood Hits	223
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELTD1_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.135348 (rank : 535)
Query Neighborhood Hits	525	Target Neighborhood Hits	269	Shared Neighborhood Hits	134
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.173867 (rank : 411)
Query Neighborhood Hits	525	Target Neighborhood Hits	288	Shared Neighborhood Hits	149
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.234595 (rank : 277)
Query Neighborhood Hits	525	Target Neighborhood Hits	382	Shared Neighborhood Hits	197
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 652)	NC score	0.205315 (rank : 321)
Query Neighborhood Hits	525	Target Neighborhood Hits	349	Shared Neighborhood Hits	170
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.226910 (rank : 284)
Query Neighborhood Hits	525	Target Neighborhood Hits	345	Shared Neighborhood Hits	185
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.087922 (rank : 638)
Query Neighborhood Hits	525	Target Neighborhood Hits	245	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.060549 (rank : 799)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	77
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

EPGN_MOUSE
θ value	θ > 10 (rank : 656)	NC score	0.054892 (rank : 833)
Query Neighborhood Hits	525	Target Neighborhood Hits	63	Shared Neighborhood Hits	41
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EREG_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.071274 (rank : 725)
Query Neighborhood Hits	525	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ESM1_MOUSE
θ value	θ > 10 (rank : 658)	NC score	0.182179 (rank : 380)
Query Neighborhood Hits	525	Target Neighborhood Hits	107	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

F13B_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.063579 (rank : 776)
Query Neighborhood Hits	525	Target Neighborhood Hits	84	Shared Neighborhood Hits	27
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

F13B_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.065133 (rank : 766)
Query Neighborhood Hits	525	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

FA7_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.126688 (rank : 544)
Query Neighborhood Hits	525	Target Neighborhood Hits	404	Shared Neighborhood Hits	179
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 662)	NC score	0.111329 (rank : 574)
Query Neighborhood Hits	525	Target Neighborhood Hits	374	Shared Neighborhood Hits	160
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FBLN1_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.272332 (rank : 232)
Query Neighborhood Hits	525	Target Neighborhood Hits	324	Shared Neighborhood Hits	197
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 664)	NC score	0.281913 (rank : 218)
Query Neighborhood Hits	525	Target Neighborhood Hits	329	Shared Neighborhood Hits	201
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.297836 (rank : 197)
Query Neighborhood Hits	525	Target Neighborhood Hits	392	Shared Neighborhood Hits	204
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.250211 (rank : 250)
Query Neighborhood Hits	525	Target Neighborhood Hits	293	Shared Neighborhood Hits	178
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 667)	NC score	0.233549 (rank : 278)
Query Neighborhood Hits	525	Target Neighborhood Hits	279	Shared Neighborhood Hits	166
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 668)	NC score	0.256335 (rank : 245)
Query Neighborhood Hits	525	Target Neighborhood Hits	278	Shared Neighborhood Hits	177
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 669)	NC score	0.249961 (rank : 252)
Query Neighborhood Hits	525	Target Neighborhood Hits	270	Shared Neighborhood Hits	172
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 670)	NC score	0.264872 (rank : 242)
Query Neighborhood Hits	525	Target Neighborhood Hits	329	Shared Neighborhood Hits	198
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 671)	NC score	0.262917 (rank : 243)
Query Neighborhood Hits	525	Target Neighborhood Hits	317	Shared Neighborhood Hits	190
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FCER2_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.135457 (rank : 534)
Query Neighborhood Hits	525	Target Neighborhood Hits	213	Shared Neighborhood Hits	56
SwissProt Accessions	P06734	Gene names	FCER2, IGEBF
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IgE receptor) (Fc-epsilon-RII) (BLAST-2) (Immunoglobulin E-binding factor) (CD23 antigen) [Contains: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form].

FCER2_MOUSE
θ value	θ > 10 (rank : 673)	NC score	0.149703 (rank : 488)
Query Neighborhood Hits	525	Target Neighborhood Hits	392	Shared Neighborhood Hits	62
SwissProt Accessions	P20693, Q61556, Q61557	Gene names	Fcer2, Fcer2a
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IGE receptor) (Fc-epsilon-RII) (CD23 antigen).

FHR5_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.057655 (rank : 821)
Query Neighborhood Hits	525	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

FINC_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.099884 (rank : 604)
Query Neighborhood Hits	525	Target Neighborhood Hits	302	Shared Neighborhood Hits	57
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.098349 (rank : 605)
Query Neighborhood Hits	525	Target Neighborhood Hits	309	Shared Neighborhood Hits	60
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FNDC3_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.052088 (rank : 844)
Query Neighborhood Hits	525	Target Neighborhood Hits	196	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.057689 (rank : 819)
Query Neighborhood Hits	525	Target Neighborhood Hits	207	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FREM1_MOUSE
θ value	θ > 10 (rank : 679)	NC score	0.065996 (rank : 758)
Query Neighborhood Hits	525	Target Neighborhood Hits	163	Shared Neighborhood Hits	52
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FSTL3_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.094788 (rank : 617)
Query Neighborhood Hits	525	Target Neighborhood Hits	162	Shared Neighborhood Hits	88
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 681)	NC score	0.087021 (rank : 642)
Query Neighborhood Hits	525	Target Neighborhood Hits	152	Shared Neighborhood Hits	81
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.064862 (rank : 767)
Query Neighborhood Hits	525	Target Neighborhood Hits	129	Shared Neighborhood Hits	52
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 683)	NC score	0.067698 (rank : 747)
Query Neighborhood Hits	525	Target Neighborhood Hits	146	Shared Neighborhood Hits	63
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GMCL1_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.066873 (rank : 750)
Query Neighborhood Hits	525	Target Neighborhood Hits	85	Shared Neighborhood Hits	41
SwissProt Accessions	Q96IK5, Q9H826, Q9H8V7, Q9H927	Gene names	GMCL1, GCL
Domain Architecture
Description	Germ cell-less protein-like 1.

GMCL1_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.067441 (rank : 749)
Query Neighborhood Hits	525	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	Q920G9, Q9DBW5, Q9QUP6	Gene names	Gmcl1, Gcl, Gcl1
Domain Architecture
Description	Germ cell-less protein-like 1 (mGcl-1) (DP-interacting protein) (DIP).

GMCLL_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.058882 (rank : 812)
Query Neighborhood Hits	525	Target Neighborhood Hits	87	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NEA9, Q8TC88, Q8TC89	Gene names	GMCL1L, GCL
Domain Architecture
Description	Germ cell-less protein-like 1-like.

GRN_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.218865 (rank : 297)
Query Neighborhood Hits	525	Target Neighborhood Hits	268	Shared Neighborhood Hits	148
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 688)	NC score	0.206361 (rank : 317)
Query Neighborhood Hits	525	Target Neighborhood Hits	248	Shared Neighborhood Hits	139
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HCFC2_MOUSE
θ value	θ > 10 (rank : 689)	NC score	0.080158 (rank : 681)
Query Neighborhood Hits	525	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HPLN1_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.059114 (rank : 808)
Query Neighborhood Hits	525	Target Neighborhood Hits	67	Shared Neighborhood Hits	14
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN1_MOUSE
θ value	θ > 10 (rank : 691)	NC score	0.059308 (rank : 807)
Query Neighborhood Hits	525	Target Neighborhood Hits	64	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN2_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.064406 (rank : 771)
Query Neighborhood Hits	525	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN2_MOUSE
θ value	θ > 10 (rank : 693)	NC score	0.065145 (rank : 765)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN3_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.060628 (rank : 797)
Query Neighborhood Hits	525	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

HPLN3_MOUSE
θ value	θ > 10 (rank : 695)	NC score	0.062082 (rank : 786)
Query Neighborhood Hits	525	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

HPLN4_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.061106 (rank : 795)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

HPLN4_MOUSE
θ value	θ > 10 (rank : 697)	NC score	0.061594 (rank : 793)
Query Neighborhood Hits	525	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

KBTB2_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.152531 (rank : 479)
Query Neighborhood Hits	525	Target Neighborhood Hits	179	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IY47, Q86Y62, Q9P239, Q9UFM7	Gene names	KBTBD2, BKLHD1, KIAA1489
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 2 (BTB and kelch domain-containing protein 1).

KBTB4_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.141119 (rank : 519)
Query Neighborhood Hits	525	Target Neighborhood Hits	187	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NVX7, Q6IA85, Q9BUC3, Q9NV76	Gene names	KBTBD4, BKLHD4
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4).

KBTB4_MOUSE
θ value	θ > 10 (rank : 700)	NC score	0.141053 (rank : 520)
Query Neighborhood Hits	525	Target Neighborhood Hits	182	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R179, Q9CQX1	Gene names	Kbtbd4, Bklhd4
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4).

KLD7B_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.152735 (rank : 478)
Query Neighborhood Hits	525	Target Neighborhood Hits	94	Shared Neighborhood Hits	61
SwissProt Accessions	Q96G42	Gene names	KLHDC7B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 7B.

KLD8A_MOUSE
θ value	θ > 10 (rank : 702)	NC score	0.168426 (rank : 434)
Query Neighborhood Hits	525	Target Neighborhood Hits	85	Shared Neighborhood Hits	71
SwissProt Accessions	Q91XA8	Gene names	Klhdc8a
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8A.

KLD8B_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.157838 (rank : 468)
Query Neighborhood Hits	525	Target Neighborhood Hits	80	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IXV7	Gene names	KLHDC8B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

KLD8B_MOUSE
θ value	θ > 10 (rank : 704)	NC score	0.163053 (rank : 452)
Query Neighborhood Hits	525	Target Neighborhood Hits	80	Shared Neighborhood Hits	66
SwissProt Accessions	Q9D2D9	Gene names	Klhdc8b
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

KLH11_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.146466 (rank : 501)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NVR0	Gene names	KLHL11
Domain Architecture	No domain graphic available
Description	Kelch-like protein 11 precursor.

KLH11_MOUSE
θ value	θ > 10 (rank : 706)	NC score	0.146963 (rank : 499)
Query Neighborhood Hits	525	Target Neighborhood Hits	177	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CE33, Q3TDZ6, Q91VP6	Gene names	Klhl11
Domain Architecture	No domain graphic available
Description	Kelch-like protein 11 precursor.

KLH21_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.152091 (rank : 482)
Query Neighborhood Hits	525	Target Neighborhood Hits	173	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UJP4, O75057	Gene names	KLHL21, KIAA0469
Domain Architecture
Description	Kelch-like protein 21.

KLHL8_HUMAN
θ value	θ > 10 (rank : 708)	NC score	0.165857 (rank : 441)
Query Neighborhood Hits	525	Target Neighborhood Hits	180	Shared Neighborhood Hits	65
SwissProt Accessions	Q9P2G9	Gene names	KLHL8, KIAA1378
Domain Architecture
Description	Kelch-like protein 8.

KLHL8_MOUSE
θ value	θ > 10 (rank : 709)	NC score	0.164783 (rank : 447)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	63
SwissProt Accessions	P59280	Gene names	Klhl8
Domain Architecture
Description	Kelch-like protein 8.

KLRA3_MOUSE
θ value	θ > 10 (rank : 710)	NC score	0.078025 (rank : 689)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	52
SwissProt Accessions	Q64329, Q61154, Q64257	Gene names	Klra3, Ly-49c, Ly49C
Domain Architecture
Description	Killer cell lectin-like receptor 3 (T-cell surface glycoprotein Ly- 49C) (Ly49-C antigen) (Lymphocyte antigen 49C) (5E6).

KLRA4_MOUSE
θ value	θ > 10 (rank : 711)	NC score	0.077767 (rank : 690)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	53
SwissProt Accessions	Q60651, O78026, Q9EPA5	Gene names	Klra4, Ly-49d, Ly49-d, Ly49d
Domain Architecture
Description	Killer cell lectin-like receptor 4 (T-cell surface glycoprotein Ly- 49D) (Ly49-D antigen) (Lymphocyte antigen 49D).

KLRA5_MOUSE
θ value	θ > 10 (rank : 712)	NC score	0.075337 (rank : 701)
Query Neighborhood Hits	525	Target Neighborhood Hits	88	Shared Neighborhood Hits	52
SwissProt Accessions	Q60652	Gene names	Klra5, Ly-49e, Ly49-e, Ly49e
Domain Architecture
Description	Killer cell lectin-like receptor 5 (T-cell surface glycoprotein Ly- 49E) (Ly49-E antigen) (Lymphocyte antigen 49E).

KLRA6_MOUSE
θ value	θ > 10 (rank : 713)	NC score	0.075900 (rank : 695)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	53
SwissProt Accessions	Q60653	Gene names	Klra6, Ly-49f, Ly49-f, Ly49F
Domain Architecture
Description	Killer cell lectin-like receptor 6 (T-cell surface glycoprotein Ly- 49F) (Ly49-F antigen) (Lymphocyte antigen 49F).

KLRA7_MOUSE
θ value	θ > 10 (rank : 714)	NC score	0.080741 (rank : 676)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	54
SwissProt Accessions	Q60654, Q60655, Q60656, Q60683	Gene names	Klra7, Ly-49g, Ly49-g, Ly49g, Ly49g4
Domain Architecture
Description	Killer cell lectin-like receptor 7 (T-cell surface glycoprotein Ly- 49G) (Ly49-G antigen) (Lymphocyte antigen 49G).

KLRA8_MOUSE
θ value	θ > 10 (rank : 715)	NC score	0.071889 (rank : 721)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	53
SwissProt Accessions	Q60682, O78027	Gene names	Klra8, Ly-49h, Ly49-h, Ly49H
Domain Architecture
Description	Killer cell lectin-like receptor 8 (T-cell surface glycoprotein Ly- 49H) (Ly49-H antigen) (Lymphocyte antigen 49H).

KLRBA_MOUSE
θ value	θ > 10 (rank : 716)	NC score	0.106073 (rank : 590)
Query Neighborhood Hits	525	Target Neighborhood Hits	104	Shared Neighborhood Hits	55
SwissProt Accessions	P27811	Gene names	Klrb1a, Ly55, Ly55a
Domain Architecture
Description	Natural killer cell surface protein P1-2 (NKR-P1 2) (NKR-P1.7).

KLRBC_MOUSE
θ value	θ > 10 (rank : 717)	NC score	0.113244 (rank : 570)
Query Neighborhood Hits	525	Target Neighborhood Hits	101	Shared Neighborhood Hits	55
SwissProt Accessions	P27814	Gene names	Klrb1c, Ly55-c, Ly55c
Domain Architecture
Description	Natural killer cell surface protein P1-40 (NKR-P1 40) (NKR-P1.9).

KLRD1_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.126454 (rank : 545)
Query Neighborhood Hits	525	Target Neighborhood Hits	101	Shared Neighborhood Hits	55
SwissProt Accessions	Q13241, O43321, O43773, Q9UBE3, Q9UEQ0	Gene names	KLRD1, CD94
Domain Architecture
Description	Natural killer cells antigen CD94 (NK cell receptor) (Killer cell lectin-like receptor subfamily D member 1) (KP43).

KLRF1_HUMAN
θ value	θ > 10 (rank : 719)	NC score	0.138803 (rank : 530)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NZS2, Q96PR2, Q96PR3, Q9NZS1	Gene names	KLRF1, ML
Domain Architecture
Description	Killer cell lectin-like receptor subfamily F member 1 (Lectin-like receptor F1) (Activating coreceptor NKp80).

KR101_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.267111 (rank : 237)
Query Neighborhood Hits	525	Target Neighborhood Hits	261	Shared Neighborhood Hits	145
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR103_HUMAN
θ value	θ > 10 (rank : 721)	NC score	0.174573 (rank : 405)
Query Neighborhood Hits	525	Target Neighborhood Hits	212	Shared Neighborhood Hits	116
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR105_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.236492 (rank : 271)
Query Neighborhood Hits	525	Target Neighborhood Hits	271	Shared Neighborhood Hits	153
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR108_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.222983 (rank : 291)
Query Neighborhood Hits	525	Target Neighborhood Hits	226	Shared Neighborhood Hits	124
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 724)	NC score	0.224705 (rank : 290)
Query Neighborhood Hits	525	Target Neighborhood Hits	226	Shared Neighborhood Hits	134
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.184225 (rank : 375)
Query Neighborhood Hits	525	Target Neighborhood Hits	232	Shared Neighborhood Hits	132
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10C_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.228031 (rank : 282)
Query Neighborhood Hits	525	Target Neighborhood Hits	219	Shared Neighborhood Hits	122
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR111_HUMAN
θ value	θ > 10 (rank : 727)	NC score	0.053775 (rank : 837)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

KR122_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.072725 (rank : 713)
Query Neighborhood Hits	525	Target Neighborhood Hits	97	Shared Neighborhood Hits	57
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KR124_HUMAN
θ value	θ > 10 (rank : 729)	NC score	0.076020 (rank : 694)
Query Neighborhood Hits	525	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR171_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.340108 (rank : 143)
Query Neighborhood Hits	525	Target Neighborhood Hits	144	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR241_HUMAN
θ value	θ > 10 (rank : 731)	NC score	0.072327 (rank : 717)
Query Neighborhood Hits	525	Target Neighborhood Hits	71	Shared Neighborhood Hits	43
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

KR410_HUMAN
θ value	θ > 10 (rank : 732)	NC score	0.151417 (rank : 486)
Query Neighborhood Hits	525	Target Neighborhood Hits	156	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR414_HUMAN
θ value	θ > 10 (rank : 733)	NC score	0.204627 (rank : 323)
Query Neighborhood Hits	525	Target Neighborhood Hits	199	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 734)	NC score	0.347188 (rank : 138)
Query Neighborhood Hits	525	Target Neighborhood Hits	217	Shared Neighborhood Hits	125
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA15_HUMAN
θ value	θ > 10 (rank : 735)	NC score	0.168733 (rank : 433)
Query Neighborhood Hits	525	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA24_HUMAN
θ value	θ > 10 (rank : 736)	NC score	0.116145 (rank : 566)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA47_HUMAN
θ value	θ > 10 (rank : 737)	NC score	0.235993 (rank : 272)
Query Neighborhood Hits	525	Target Neighborhood Hits	204	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

LCE1A_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.143258 (rank : 510)
Query Neighborhood Hits	525	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 739)	NC score	0.187920 (rank : 360)
Query Neighborhood Hits	525	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 740)	NC score	0.198961 (rank : 333)
Query Neighborhood Hits	525	Target Neighborhood Hits	65	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.141529 (rank : 518)
Query Neighborhood Hits	525	Target Neighborhood Hits	44	Shared Neighborhood Hits	25
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 742)	NC score	0.142138 (rank : 516)
Query Neighborhood Hits	525	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.149086 (rank : 489)
Query Neighborhood Hits	525	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 744)	NC score	0.094879 (rank : 616)
Query Neighborhood Hits	525	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.086336 (rank : 647)
Query Neighborhood Hits	525	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.096981 (rank : 608)
Query Neighborhood Hits	525	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 747)	NC score	0.091504 (rank : 629)
Query Neighborhood Hits	525	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.123095 (rank : 551)
Query Neighborhood Hits	525	Target Neighborhood Hits	29	Shared Neighborhood Hits	18
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.069425 (rank : 738)
Query Neighborhood Hits	525	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE4A_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.125016 (rank : 548)
Query Neighborhood Hits	525	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.056127 (rank : 827)
Query Neighborhood Hits	525	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LDLR_HUMAN
θ value	θ > 10 (rank : 752)	NC score	0.243359 (rank : 264)
Query Neighborhood Hits	525	Target Neighborhood Hits	375	Shared Neighborhood Hits	219
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 753)	NC score	0.234698 (rank : 274)
Query Neighborhood Hits	525	Target Neighborhood Hits	382	Shared Neighborhood Hits	214
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LIT1_MOUSE
θ value	θ > 10 (rank : 754)	NC score	0.107818 (rank : 585)
Query Neighborhood Hits	525	Target Neighborhood Hits	114	Shared Neighborhood Hits	53
SwissProt Accessions	P43137	Gene names	Reg1
Domain Architecture
Description	Lithostathine 1 precursor (Pancreatic stone protein 1) (PSP) (Pancreatic thread protein 1) (PTP) (Islet of Langerhans regenerating protein 1) (REG 1).

LIT2_MOUSE
θ value	θ > 10 (rank : 755)	NC score	0.107557 (rank : 586)
Query Neighborhood Hits	525	Target Neighborhood Hits	111	Shared Neighborhood Hits	51
SwissProt Accessions	Q08731	Gene names	Reg2
Domain Architecture
Description	Lithostathine 2 precursor (Pancreatic stone protein 2) (PSP) (Pancreatic thread protein 2) (PTP) (Islet of Langerhans regenerating protein 2) (REG 2).

LORI_MOUSE
θ value	θ > 10 (rank : 756)	NC score	0.100674 (rank : 600)
Query Neighborhood Hits	525	Target Neighborhood Hits	47	Shared Neighborhood Hits	22
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRP10_MOUSE
θ value	θ > 10 (rank : 757)	NC score	0.197990 (rank : 336)
Query Neighborhood Hits	525	Target Neighborhood Hits	169	Shared Neighborhood Hits	94
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP11_HUMAN
θ value	θ > 10 (rank : 758)	NC score	0.050819 (rank : 856)
Query Neighborhood Hits	525	Target Neighborhood Hits	82	Shared Neighborhood Hits	30
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP11_MOUSE
θ value	θ > 10 (rank : 759)	NC score	0.050893 (rank : 854)
Query Neighborhood Hits	525	Target Neighborhood Hits	81	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP5_HUMAN
θ value	θ > 10 (rank : 760)	NC score	0.118330 (rank : 563)
Query Neighborhood Hits	525	Target Neighborhood Hits	224	Shared Neighborhood Hits	106
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 761)	NC score	0.120992 (rank : 558)
Query Neighborhood Hits	525	Target Neighborhood Hits	236	Shared Neighborhood Hits	111
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 762)	NC score	0.122984 (rank : 552)
Query Neighborhood Hits	525	Target Neighborhood Hits	235	Shared Neighborhood Hits	115
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 763)	NC score	0.121111 (rank : 557)
Query Neighborhood Hits	525	Target Neighborhood Hits	232	Shared Neighborhood Hits	112
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP8_HUMAN
θ value	θ > 10 (rank : 764)	NC score	0.221320 (rank : 293)
Query Neighborhood Hits	525	Target Neighborhood Hits	346	Shared Neighborhood Hits	184
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 765)	NC score	0.238571 (rank : 270)
Query Neighborhood Hits	525	Target Neighborhood Hits	385	Shared Neighborhood Hits	200
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LY49A_MOUSE
θ value	θ > 10 (rank : 766)	NC score	0.079653 (rank : 683)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	55
SwissProt Accessions	P20937	Gene names	Klra1, Ly-49, Ly-49a, Ly49, Ly49A
Domain Architecture
Description	T-cell surface glycoprotein YE1/48 (T lymphocyte antigen A1) (Ly49-A antigen) (Lymphocyte antigen 49A).

MASP1_MOUSE
θ value	θ > 10 (rank : 767)	NC score	0.156540 (rank : 472)
Query Neighborhood Hits	525	Target Neighborhood Hits	364	Shared Neighborhood Hits	125
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MATN1_HUMAN
θ value	θ > 10 (rank : 768)	NC score	0.066595 (rank : 753)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	78
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 769)	NC score	0.065303 (rank : 762)
Query Neighborhood Hits	525	Target Neighborhood Hits	186	Shared Neighborhood Hits	74
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN2_HUMAN
θ value	θ > 10 (rank : 770)	NC score	0.256115 (rank : 247)
Query Neighborhood Hits	525	Target Neighborhood Hits	365	Shared Neighborhood Hits	186
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 771)	NC score	0.248495 (rank : 256)
Query Neighborhood Hits	525	Target Neighborhood Hits	356	Shared Neighborhood Hits	182
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 772)	NC score	0.185600 (rank : 367)
Query Neighborhood Hits	525	Target Neighborhood Hits	268	Shared Neighborhood Hits	143
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 773)	NC score	0.186611 (rank : 361)
Query Neighborhood Hits	525	Target Neighborhood Hits	261	Shared Neighborhood Hits	146
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 774)	NC score	0.192523 (rank : 346)
Query Neighborhood Hits	525	Target Neighborhood Hits	287	Shared Neighborhood Hits	157
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 775)	NC score	0.181998 (rank : 381)
Query Neighborhood Hits	525	Target Neighborhood Hits	277	Shared Neighborhood Hits	150
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MBL1_MOUSE
θ value	θ > 10 (rank : 776)	NC score	0.072514 (rank : 714)
Query Neighborhood Hits	525	Target Neighborhood Hits	147	Shared Neighborhood Hits	40
SwissProt Accessions	P39039	Gene names	Mbl1
Domain Architecture
Description	Mannose-binding protein A precursor (MBP-A) (Mannan-binding protein) (Ra-reactive factor polysaccharide-binding component p28B polypeptide) (RaRF p28B).

MBL2_HUMAN
θ value	θ > 10 (rank : 777)	NC score	0.072831 (rank : 712)
Query Neighborhood Hits	525	Target Neighborhood Hits	161	Shared Neighborhood Hits	42
SwissProt Accessions	P11226, Q86SI4, Q96KE4, Q96TF7, Q96TF8, Q96TF9	Gene names	MBL2, MBL
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (MBP1) (Mannan-binding protein) (Mannose-binding lectin).

MBL2_MOUSE
θ value	θ > 10 (rank : 778)	NC score	0.073785 (rank : 707)
Query Neighborhood Hits	525	Target Neighborhood Hits	148	Shared Neighborhood Hits	42
SwissProt Accessions	P41317	Gene names	Mbl2
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (Mannan-binding protein) (RA-reactive factor P28A subunit) (RARF/P28A).

MCP_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.066121 (rank : 757)
Query Neighborhood Hits	525	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

MCP_MOUSE
θ value	θ > 10 (rank : 780)	NC score	0.071287 (rank : 723)
Query Neighborhood Hits	525	Target Neighborhood Hits	79	Shared Neighborhood Hits	24
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

MCSP_MOUSE
θ value	θ > 10 (rank : 781)	NC score	0.085914 (rank : 651)
Query Neighborhood Hits	525	Target Neighborhood Hits	108	Shared Neighborhood Hits	40
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEP1A_HUMAN
θ value	θ > 10 (rank : 782)	NC score	0.159676 (rank : 461)
Query Neighborhood Hits	525	Target Neighborhood Hits	162	Shared Neighborhood Hits	105
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 783)	NC score	0.163854 (rank : 449)
Query Neighborhood Hits	525	Target Neighborhood Hits	166	Shared Neighborhood Hits	109
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_HUMAN
θ value	θ > 10 (rank : 784)	NC score	0.122912 (rank : 553)
Query Neighborhood Hits	525	Target Neighborhood Hits	98	Shared Neighborhood Hits	56
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1B_MOUSE
θ value	θ > 10 (rank : 785)	NC score	0.151538 (rank : 485)
Query Neighborhood Hits	525	Target Neighborhood Hits	127	Shared Neighborhood Hits	85
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MFGM_HUMAN
θ value	θ > 10 (rank : 786)	NC score	0.145361 (rank : 505)
Query Neighborhood Hits	525	Target Neighborhood Hits	150	Shared Neighborhood Hits	110
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MKS3_HUMAN
θ value	θ > 10 (rank : 787)	NC score	0.089036 (rank : 635)
Query Neighborhood Hits	525	Target Neighborhood Hits	79	Shared Neighborhood Hits	60
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

MKS3_MOUSE
θ value	θ > 10 (rank : 788)	NC score	0.122417 (rank : 554)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MMRN1_HUMAN
θ value	θ > 10 (rank : 789)	NC score	0.112953 (rank : 571)
Query Neighborhood Hits	525	Target Neighborhood Hits	636	Shared Neighborhood Hits	135
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MT1F_HUMAN
θ value	θ > 10 (rank : 790)	NC score	0.067815 (rank : 745)
Query Neighborhood Hits	525	Target Neighborhood Hits	73	Shared Neighborhood Hits	45
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1G_HUMAN
θ value	θ > 10 (rank : 791)	NC score	0.075776 (rank : 696)
Query Neighborhood Hits	525	Target Neighborhood Hits	63	Shared Neighborhood Hits	35
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

MT1I_HUMAN
θ value	θ > 10 (rank : 792)	NC score	0.062024 (rank : 787)
Query Neighborhood Hits	525	Target Neighborhood Hits	64	Shared Neighborhood Hits	41
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

MT1M_HUMAN
θ value	θ > 10 (rank : 793)	NC score	0.059645 (rank : 804)
Query Neighborhood Hits	525	Target Neighborhood Hits	72	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

MT1_MOUSE
θ value	θ > 10 (rank : 794)	NC score	0.093797 (rank : 624)
Query Neighborhood Hits	525	Target Neighborhood Hits	72	Shared Neighborhood Hits	43
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_HUMAN
θ value	θ > 10 (rank : 795)	NC score	0.065160 (rank : 764)
Query Neighborhood Hits	525	Target Neighborhood Hits	69	Shared Neighborhood Hits	45
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

MT2_MOUSE
θ value	θ > 10 (rank : 796)	NC score	0.102131 (rank : 596)
Query Neighborhood Hits	525	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT3_MOUSE
θ value	θ > 10 (rank : 797)	NC score	0.209996 (rank : 309)
Query Neighborhood Hits	525	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_HUMAN
θ value	θ > 10 (rank : 798)	NC score	0.112384 (rank : 573)
Query Neighborhood Hits	525	Target Neighborhood Hits	83	Shared Neighborhood Hits	53
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 799)	NC score	0.139043 (rank : 528)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	68
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_HUMAN
θ value	θ > 10 (rank : 800)	NC score	0.105058 (rank : 592)
Query Neighborhood Hits	525	Target Neighborhood Hits	164	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MUC13_MOUSE
θ value	θ > 10 (rank : 801)	NC score	0.147604 (rank : 494)
Query Neighborhood Hits	525	Target Neighborhood Hits	447	Shared Neighborhood Hits	137
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

NFX1_HUMAN
θ value	θ > 10 (rank : 802)	NC score	0.184934 (rank : 372)
Query Neighborhood Hits	525	Target Neighborhood Hits	405	Shared Neighborhood Hits	138
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 803)	NC score	0.275937 (rank : 225)
Query Neighborhood Hits	525	Target Neighborhood Hits	329	Shared Neighborhood Hits	204
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 804)	NC score	0.273853 (rank : 229)
Query Neighborhood Hits	525	Target Neighborhood Hits	335	Shared Neighborhood Hits	203
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_MOUSE
θ value	θ > 10 (rank : 805)	NC score	0.269288 (rank : 235)
Query Neighborhood Hits	525	Target Neighborhood Hits	338	Shared Neighborhood Hits	202
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NKG2D_HUMAN
θ value	θ > 10 (rank : 806)	NC score	0.142305 (rank : 515)
Query Neighborhood Hits	525	Target Neighborhood Hits	98	Shared Neighborhood Hits	53
SwissProt Accessions	P26718, Q9NR41	Gene names	KLRK1, NKG2D
Domain Architecture
Description	NKG2-D type II integral membrane protein (NKG2-D-activating NK receptor) (NK cell receptor D) (Killer cell lectin-like receptor subfamily K member 1) (CD314 antigen).

NKG2D_MOUSE
θ value	θ > 10 (rank : 807)	NC score	0.144627 (rank : 507)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	55
SwissProt Accessions	O54709	Gene names	Klrk1, Nkg2d
Domain Architecture
Description	NKG2-D type II integral membrane protein (NKG2-D-activating NK receptor) (NK cell receptor D) (Killer cell lectin-like receptor subfamily K member 1) (CD314 antigen).

NKG2E_HUMAN
θ value	θ > 10 (rank : 808)	NC score	0.091163 (rank : 630)
Query Neighborhood Hits	525	Target Neighborhood Hits	96	Shared Neighborhood Hits	51
SwissProt Accessions	Q07444, Q96RL0, Q9UP04	Gene names	KLRC3, NKG2E
Domain Architecture
Description	NKG2-E type II integral membrane protein (NKG2-E-activating NK receptor) (NK cell receptor E).

NRG4_HUMAN
θ value	θ > 10 (rank : 809)	NC score	0.084797 (rank : 656)
Query Neighborhood Hits	525	Target Neighborhood Hits	85	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 810)	NC score	0.083611 (rank : 662)
Query Neighborhood Hits	525	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRX1B_HUMAN
θ value	θ > 10 (rank : 811)	NC score	0.051152 (rank : 851)
Query Neighborhood Hits	525	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

NRX3B_HUMAN
θ value	θ > 10 (rank : 812)	NC score	0.054324 (rank : 835)
Query Neighborhood Hits	525	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HDB5	Gene names	NRXN3, KIAA0743
Domain Architecture	No domain graphic available
Description	Neurexin-3-beta precursor (Neurexin III-beta).

OLR1_MOUSE
θ value	θ > 10 (rank : 813)	NC score	0.103853 (rank : 595)
Query Neighborhood Hits	525	Target Neighborhood Hits	596	Shared Neighborhood Hits	68
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

PAP2_HUMAN
θ value	θ > 10 (rank : 814)	NC score	0.060402 (rank : 800)
Query Neighborhood Hits	525	Target Neighborhood Hits	106	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PAPPA_HUMAN
θ value	θ > 10 (rank : 815)	NC score	0.085593 (rank : 654)
Query Neighborhood Hits	525	Target Neighborhood Hits	161	Shared Neighborhood Hits	61
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	θ > 10 (rank : 816)	NC score	0.088953 (rank : 636)
Query Neighborhood Hits	525	Target Neighborhood Hits	153	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PCOC1_HUMAN
θ value	θ > 10 (rank : 817)	NC score	0.290029 (rank : 210)
Query Neighborhood Hits	525	Target Neighborhood Hits	146	Shared Neighborhood Hits	55
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCSK6_HUMAN
θ value	θ > 10 (rank : 818)	NC score	0.148188 (rank : 492)
Query Neighborhood Hits	525	Target Neighborhood Hits	298	Shared Neighborhood Hits	134
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PDGFD_HUMAN
θ value	θ > 10 (rank : 819)	NC score	0.221545 (rank : 292)
Query Neighborhood Hits	525	Target Neighborhood Hits	74	Shared Neighborhood Hits	47
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 820)	NC score	0.219198 (rank : 295)
Query Neighborhood Hits	525	Target Neighborhood Hits	72	Shared Neighborhood Hits	46
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PERT_HUMAN
θ value	θ > 10 (rank : 821)	NC score	0.118489 (rank : 562)
Query Neighborhood Hits	525	Target Neighborhood Hits	221	Shared Neighborhood Hits	110
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 822)	NC score	0.108957 (rank : 584)
Query Neighborhood Hits	525	Target Neighborhood Hits	221	Shared Neighborhood Hits	105
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGH1_HUMAN
θ value	θ > 10 (rank : 823)	NC score	0.067989 (rank : 743)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	64
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH1_MOUSE
θ value	θ > 10 (rank : 824)	NC score	0.078755 (rank : 688)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	70
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.086259 (rank : 648)
Query Neighborhood Hits	525	Target Neighborhood Hits	103	Shared Neighborhood Hits	74
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PHXR5_MOUSE
θ value	θ > 10 (rank : 826)	NC score	0.068397 (rank : 742)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PLXB1_MOUSE
θ value	θ > 10 (rank : 827)	NC score	0.054748 (rank : 834)
Query Neighborhood Hits	525	Target Neighborhood Hits	259	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PLXC1_HUMAN
θ value	θ > 10 (rank : 828)	NC score	0.058477 (rank : 814)
Query Neighborhood Hits	525	Target Neighborhood Hits	94	Shared Neighborhood Hits	24
SwissProt Accessions	O60486, Q59H25	Gene names	PLXNC1, VESPR
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PROZ_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.234675 (rank : 276)
Query Neighborhood Hits	525	Target Neighborhood Hits	422	Shared Neighborhood Hits	200
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

RCBT1_HUMAN
θ value	θ > 10 (rank : 830)	NC score	0.062365 (rank : 784)
Query Neighborhood Hits	525	Target Neighborhood Hits	158	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

RCBT1_MOUSE
θ value	θ > 10 (rank : 831)	NC score	0.062373 (rank : 783)
Query Neighborhood Hits	525	Target Neighborhood Hits	157	Shared Neighborhood Hits	54
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

RECK_HUMAN
θ value	θ > 10 (rank : 832)	NC score	0.100674 (rank : 601)
Query Neighborhood Hits	525	Target Neighborhood Hits	189	Shared Neighborhood Hits	91
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 833)	NC score	0.083085 (rank : 663)
Query Neighborhood Hits	525	Target Neighborhood Hits	158	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

REG1A_HUMAN
θ value	θ > 10 (rank : 834)	NC score	0.103869 (rank : 594)
Query Neighborhood Hits	525	Target Neighborhood Hits	112	Shared Neighborhood Hits	49
SwissProt Accessions	P05451, P11379	Gene names	REG1A, PSPS, REG
Domain Architecture
Description	Lithostathine 1 alpha precursor (Pancreatic stone protein) (PSP) (Pancreatic thread protein) (PTP) (Islet of Langerhans regenerating protein) (REG) (Regenerating protein I alpha) (Islet cells regeneration factor) (ICRF).

REG1B_HUMAN
θ value	θ > 10 (rank : 835)	NC score	0.109788 (rank : 578)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	57
SwissProt Accessions	P48304	Gene names	REG1B, REGL
Domain Architecture
Description	Lithostathine 1 beta precursor (Regenerating protein I beta).

REG3A_HUMAN
θ value	θ > 10 (rank : 836)	NC score	0.072212 (rank : 718)
Query Neighborhood Hits	525	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	Q06141	Gene names	REG3A, HIP, PAP, PAP1
Domain Architecture
Description	Regenerating islet-derived protein 3 alpha precursor (Reg III-alpha) (Pancreatitis-associated protein 1).

REG3A_MOUSE
θ value	θ > 10 (rank : 837)	NC score	0.087062 (rank : 641)
Query Neighborhood Hits	525	Target Neighborhood Hits	80	Shared Neighborhood Hits	41
SwissProt Accessions	O09037	Gene names	Reg3a, Pap2
Domain Architecture
Description	Regenerating islet-derived protein 3 alpha precursor (Reg III-alpha) (Pancreatitis-associated protein 2) (Lithostathine 3) (Islet of Langerhans regenerating protein 3).

REG3B_MOUSE
θ value	θ > 10 (rank : 838)	NC score	0.082754 (rank : 667)
Query Neighborhood Hits	525	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	P35230	Gene names	Reg3b, Pap, Pap1
Domain Architecture
Description	Regenerating islet-derived protein 3 beta precursor (Reg III-beta) (Pancreatitis-associated protein 1).

REG3G_HUMAN
θ value	θ > 10 (rank : 839)	NC score	0.072867 (rank : 711)
Query Neighborhood Hits	525	Target Neighborhood Hits	86	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UW15, Q6FH18	Gene names	REG3G, PAP1B
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 3 gamma precursor (Reg III-gamma) (Pancreatitis-associated protein 1B) (PAP IB).

REG3G_MOUSE
θ value	θ > 10 (rank : 840)	NC score	0.088132 (rank : 637)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	46
SwissProt Accessions	O09049	Gene names	Reg3g, Pap3
Domain Architecture
Description	Regenerating islet-derived protein 3 gamma precursor (Reg III-gamma) (Pancreatitis-associated protein 3).

RHBT3_HUMAN
θ value	θ > 10 (rank : 841)	NC score	0.062572 (rank : 780)
Query Neighborhood Hits	525	Target Neighborhood Hits	116	Shared Neighborhood Hits	46
SwissProt Accessions	O94955, Q8IW06	Gene names	RHOBTB3, KIAA0878
Domain Architecture
Description	Rho-related BTB domain-containing protein 3.

RHBT3_MOUSE
θ value	θ > 10 (rank : 842)	NC score	0.062472 (rank : 781)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CTN4, Q80X55, Q9CVT0	Gene names	Rhobtb3, Kiaa0878
Domain Architecture
Description	Rho-related BTB domain-containing protein 3.

RSPO3_HUMAN
θ value	θ > 10 (rank : 843)	NC score	0.051149 (rank : 852)
Query Neighborhood Hits	525	Target Neighborhood Hits	128	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO4_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.062965 (rank : 779)
Query Neighborhood Hits	525	Target Neighborhood Hits	110	Shared Neighborhood Hits	55
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 845)	NC score	0.058920 (rank : 811)
Query Neighborhood Hits	525	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SEZ6L_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.230055 (rank : 281)
Query Neighborhood Hits	525	Target Neighborhood Hits	289	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SFTA1_HUMAN
θ value	θ > 10 (rank : 847)	NC score	0.060649 (rank : 796)
Query Neighborhood Hits	525	Target Neighborhood Hits	169	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IWL2, P07714, Q5RIR5, Q5RIR7, Q6PIT0, Q8TC19	Gene names	SFTPA1, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A1 precursor (SP-A1) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

SFTA2_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.059531 (rank : 805)
Query Neighborhood Hits	525	Target Neighborhood Hits	169	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IWL1, P07714, Q5RIR8, Q5RIR9	Gene names	SFTPA2, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A2 precursor (SP-A2) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

SFTPA_MOUSE
θ value	θ > 10 (rank : 849)	NC score	0.051925 (rank : 845)
Query Neighborhood Hits	525	Target Neighborhood Hits	169	Shared Neighborhood Hits	38
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

SFTPD_MOUSE
θ value	θ > 10 (rank : 850)	NC score	0.052159 (rank : 843)
Query Neighborhood Hits	525	Target Neighborhood Hits	217	Shared Neighborhood Hits	40
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

SHBG_HUMAN
θ value	θ > 10 (rank : 851)	NC score	0.106465 (rank : 589)
Query Neighborhood Hits	525	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SHBG_MOUSE
θ value	θ > 10 (rank : 852)	NC score	0.100925 (rank : 599)
Query Neighborhood Hits	525	Target Neighborhood Hits	50	Shared Neighborhood Hits	35
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SPIT1_HUMAN
θ value	θ > 10 (rank : 853)	NC score	0.051235 (rank : 850)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	34
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPOP_HUMAN
θ value	θ > 10 (rank : 854)	NC score	0.094430 (rank : 620)
Query Neighborhood Hits	525	Target Neighborhood Hits	168	Shared Neighborhood Hits	53
SwissProt Accessions	O43791	Gene names	SPOP
Domain Architecture
Description	Speckle-type POZ protein.

SPOP_MOUSE
θ value	θ > 10 (rank : 855)	NC score	0.094430 (rank : 621)
Query Neighborhood Hits	525	Target Neighborhood Hits	168	Shared Neighborhood Hits	53
SwissProt Accessions	Q6ZWS8	Gene names	Spop, Pcif1
Domain Architecture	No domain graphic available
Description	Speckle-type POZ protein (PDX-1 C-terminal-interacting factor 1) (PCIF1).

SRPX_HUMAN
θ value	θ > 10 (rank : 856)	NC score	0.073932 (rank : 705)
Query Neighborhood Hits	525	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

SRPX_MOUSE
θ value	θ > 10 (rank : 857)	NC score	0.075362 (rank : 700)
Query Neighborhood Hits	525	Target Neighborhood Hits	75	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

SUSD2_HUMAN
θ value	θ > 10 (rank : 858)	NC score	0.053838 (rank : 836)
Query Neighborhood Hits	525	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD2_MOUSE
θ value	θ > 10 (rank : 859)	NC score	0.055208 (rank : 831)
Query Neighborhood Hits	525	Target Neighborhood Hits	104	Shared Neighborhood Hits	32
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD4_HUMAN
θ value	θ > 10 (rank : 860)	NC score	0.055568 (rank : 829)
Query Neighborhood Hits	525	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SUSD4_MOUSE
θ value	θ > 10 (rank : 861)	NC score	0.056256 (rank : 826)
Query Neighborhood Hits	525	Target Neighborhood Hits	122	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

TDPZ1_MOUSE
θ value	θ > 10 (rank : 862)	NC score	0.091004 (rank : 631)
Query Neighborhood Hits	525	Target Neighborhood Hits	164	Shared Neighborhood Hits	53
SwissProt Accessions	Q717B3, Q71G58, Q8BZV7, Q8VI39	Gene names	Tdpoz1, 2cpoz56, Mapp2, Spopl1
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 1 (MAPP family protein 2).

TDPZ2_MOUSE
θ value	θ > 10 (rank : 863)	NC score	0.082872 (rank : 665)
Query Neighborhood Hits	525	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q717B2	Gene names	Tdpoz2
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 2.

TDPZ3_MOUSE
θ value	θ > 10 (rank : 864)	NC score	0.082739 (rank : 668)
Query Neighborhood Hits	525	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	Q717B4	Gene names	Tdpoz3
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 3.

TDPZ4_MOUSE
θ value	θ > 10 (rank : 865)	NC score	0.087802 (rank : 639)
Query Neighborhood Hits	525	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q6YCH2	Gene names	Tdpoz4
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 4.

TDPZ5_MOUSE
θ value	θ > 10 (rank : 866)	NC score	0.081589 (rank : 672)
Query Neighborhood Hits	525	Target Neighborhood Hits	160	Shared Neighborhood Hits	53
SwissProt Accessions	Q6YCH1	Gene names	Tdpoz5
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 5.

TECTA_HUMAN
θ value	θ > 10 (rank : 867)	NC score	0.082040 (rank : 671)
Query Neighborhood Hits	525	Target Neighborhood Hits	239	Shared Neighborhood Hits	122
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 868)	NC score	0.094615 (rank : 619)
Query Neighborhood Hits	525	Target Neighborhood Hits	244	Shared Neighborhood Hits	134
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 869)	NC score	0.147308 (rank : 497)
Query Neighborhood Hits	525	Target Neighborhood Hits	211	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 870)	NC score	0.148806 (rank : 490)
Query Neighborhood Hits	525	Target Neighborhood Hits	214	Shared Neighborhood Hits	120
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TETN_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.082949 (rank : 664)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	P05452	Gene names	CLEC3B, TNA
Domain Architecture
Description	Tetranectin precursor (TN) (C-type lectin domain family 3 member B) (Plasminogen kringle 4-binding protein).

TETN_MOUSE
θ value	θ > 10 (rank : 872)	NC score	0.067531 (rank : 748)
Query Neighborhood Hits	525	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	P43025	Gene names	Clec3b, Tna
Domain Architecture
Description	Tetranectin precursor (TN) (C-type lectin domain family 3 member B) (Plasminogen kringle 4-binding protein).

TMPS6_HUMAN
θ value	θ > 10 (rank : 873)	NC score	0.086693 (rank : 644)
Query Neighborhood Hits	525	Target Neighborhood Hits	338	Shared Neighborhood Hits	126
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 874)	NC score	0.080993 (rank : 674)
Query Neighborhood Hits	525	Target Neighborhood Hits	341	Shared Neighborhood Hits	124
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_HUMAN
θ value	θ > 10 (rank : 875)	NC score	0.079003 (rank : 686)
Query Neighborhood Hits	525	Target Neighborhood Hits	275	Shared Neighborhood Hits	86
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 876)	NC score	0.076426 (rank : 693)
Query Neighborhood Hits	525	Target Neighborhood Hits	275	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TNR11_HUMAN
θ value	θ > 10 (rank : 877)	NC score	0.059462 (rank : 806)
Query Neighborhood Hits	525	Target Neighborhood Hits	135	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR14_HUMAN
θ value	θ > 10 (rank : 878)	NC score	0.106600 (rank : 588)
Query Neighborhood Hits	525	Target Neighborhood Hits	149	Shared Neighborhood Hits	68
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR16_HUMAN
θ value	θ > 10 (rank : 879)	NC score	0.139792 (rank : 527)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	86
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	θ > 10 (rank : 880)	NC score	0.124414 (rank : 549)
Query Neighborhood Hits	525	Target Neighborhood Hits	178	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR19_HUMAN
θ value	θ > 10 (rank : 881)	NC score	0.061740 (rank : 789)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 882)	NC score	0.082491 (rank : 669)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR1B_HUMAN
θ value	θ > 10 (rank : 883)	NC score	0.050837 (rank : 855)
Query Neighborhood Hits	525	Target Neighborhood Hits	127	Shared Neighborhood Hits	47
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR22_MOUSE
θ value	θ > 10 (rank : 884)	NC score	0.097069 (rank : 607)
Query Neighborhood Hits	525	Target Neighborhood Hits	97	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR25_HUMAN
θ value	θ > 10 (rank : 885)	NC score	0.114893 (rank : 568)
Query Neighborhood Hits	525	Target Neighborhood Hits	172	Shared Neighborhood Hits	71
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR26_MOUSE
θ value	θ > 10 (rank : 886)	NC score	0.058265 (rank : 815)
Query Neighborhood Hits	525	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR3_HUMAN
θ value	θ > 10 (rank : 887)	NC score	0.061306 (rank : 794)
Query Neighborhood Hits	525	Target Neighborhood Hits	145	Shared Neighborhood Hits	47
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR3_MOUSE
θ value	θ > 10 (rank : 888)	NC score	0.075461 (rank : 698)
Query Neighborhood Hits	525	Target Neighborhood Hits	113	Shared Neighborhood Hits	55
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR4_MOUSE
θ value	θ > 10 (rank : 889)	NC score	0.154736 (rank : 474)
Query Neighborhood Hits	525	Target Neighborhood Hits	137	Shared Neighborhood Hits	63
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR5_MOUSE
θ value	θ > 10 (rank : 890)	NC score	0.070601 (rank : 727)
Query Neighborhood Hits	525	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR6B_HUMAN
θ value	θ > 10 (rank : 891)	NC score	0.051066 (rank : 853)
Query Neighborhood Hits	525	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR6_MOUSE
θ value	θ > 10 (rank : 892)	NC score	0.057822 (rank : 818)
Query Neighborhood Hits	525	Target Neighborhood Hits	99	Shared Neighborhood Hits	47
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
θ value	θ > 10 (rank : 893)	NC score	0.101277 (rank : 597)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	64
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR7_MOUSE
θ value	θ > 10 (rank : 894)	NC score	0.079250 (rank : 685)
Query Neighborhood Hits	525	Target Neighborhood Hits	112	Shared Neighborhood Hits	53
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR8_HUMAN
θ value	θ > 10 (rank : 895)	NC score	0.060190 (rank : 801)
Query Neighborhood Hits	525	Target Neighborhood Hits	198	Shared Neighborhood Hits	64
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR8_MOUSE
θ value	θ > 10 (rank : 896)	NC score	0.070339 (rank : 730)
Query Neighborhood Hits	525	Target Neighborhood Hits	208	Shared Neighborhood Hits	68
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR9_HUMAN
θ value	θ > 10 (rank : 897)	NC score	0.079734 (rank : 682)
Query Neighborhood Hits	525	Target Neighborhood Hits	166	Shared Neighborhood Hits	78
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TR19L_MOUSE
θ value	θ > 10 (rank : 898)	NC score	0.051777 (rank : 846)
Query Neighborhood Hits	525	Target Neighborhood Hits	85	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TRBM_HUMAN
θ value	θ > 10 (rank : 899)	NC score	0.275192 (rank : 228)
Query Neighborhood Hits	525	Target Neighborhood Hits	339	Shared Neighborhood Hits	198
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 900)	NC score	0.271422 (rank : 233)
Query Neighborhood Hits	525	Target Neighborhood Hits	361	Shared Neighborhood Hits	208
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

UROK_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.057949 (rank : 816)
Query Neighborhood Hits	525	Target Neighborhood Hits	272	Shared Neighborhood Hits	111
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROL1_HUMAN
θ value	θ > 10 (rank : 902)	NC score	0.097875 (rank : 606)
Query Neighborhood Hits	525	Target Neighborhood Hits	213	Shared Neighborhood Hits	98
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 903)	NC score	0.109905 (rank : 577)
Query Neighborhood Hits	525	Target Neighborhood Hits	235	Shared Neighborhood Hits	103
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROM_HUMAN
θ value	θ > 10 (rank : 904)	NC score	0.284124 (rank : 217)
Query Neighborhood Hits	525	Target Neighborhood Hits	284	Shared Neighborhood Hits	199
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 905)	NC score	0.276415 (rank : 224)
Query Neighborhood Hits	525	Target Neighborhood Hits	276	Shared Neighborhood Hits	196
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VEGFC_HUMAN
θ value	θ > 10 (rank : 906)	NC score	0.086418 (rank : 646)
Query Neighborhood Hits	525	Target Neighborhood Hits	128	Shared Neighborhood Hits	80
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VEGFC_MOUSE
θ value	θ > 10 (rank : 907)	NC score	0.080504 (rank : 679)
Query Neighborhood Hits	525	Target Neighborhood Hits	119	Shared Neighborhood Hits	74
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VLDLR_HUMAN
θ value	θ > 10 (rank : 908)	NC score	0.248479 (rank : 257)
Query Neighborhood Hits	525	Target Neighborhood Hits	383	Shared Neighborhood Hits	210
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VWF_HUMAN
θ value	θ > 10 (rank : 909)	NC score	0.144913 (rank : 506)
Query Neighborhood Hits	525	Target Neighborhood Hits	396	Shared Neighborhood Hits	168
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
θ value	θ > 10 (rank : 910)	NC score	0.133213 (rank : 538)
Query Neighborhood Hits	525	Target Neighborhood Hits	381	Shared Neighborhood Hits	163
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WFDC3_HUMAN
θ value	θ > 10 (rank : 911)	NC score	0.075455 (rank : 699)
Query Neighborhood Hits	525	Target Neighborhood Hits	138	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

XLKD1_HUMAN
θ value	θ > 10 (rank : 912)	NC score	0.050666 (rank : 857)
Query Neighborhood Hits	525	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5Y7, Q8TC18, Q9UNF4	Gene names	XLKD1, CRSBP1, HAR
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Hyaluronic acid receptor) (Extracellular link domain-containing protein 1).

ZAN_HUMAN
θ value	θ > 10 (rank : 913)	NC score	0.173844 (rank : 412)
Query Neighborhood Hits	525	Target Neighborhood Hits	679	Shared Neighborhood Hits	227
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZP3R_MOUSE
θ value	θ > 10 (rank : 914)	NC score	0.068591 (rank : 740)
Query Neighborhood Hits	525	Target Neighborhood Hits	81	Shared Neighborhood Hits	23
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

Hits sorted by NC score

ATRN_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	525	Target Neighborhood Hits	525	Shared Neighborhood Hits	525
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
NC score	0.987661 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	525	Target Neighborhood Hits	519	Shared Neighborhood Hits	481
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

MEGF8_MOUSE
NC score	0.682119 (rank : 3)	θ value	2.11701e-41 (rank : 3)
Query Neighborhood Hits	525	Target Neighborhood Hits	520	Shared Neighborhood Hits	318
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_HUMAN
NC score	0.670871 (rank : 4)	θ value	4.27553e-34 (rank : 4)
Query Neighborhood Hits	525	Target Neighborhood Hits	528	Shared Neighborhood Hits	318
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
NC score	0.608603 (rank : 5)	θ value	1.9326e-10 (rank : 34)
Query Neighborhood Hits	525	Target Neighborhood Hits	557	Shared Neighborhood Hits	240
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMC3_HUMAN
NC score	0.596971 (rank : 6)	θ value	1.33837e-11 (rank : 23)
Query Neighborhood Hits	525	Target Neighborhood Hits	588	Shared Neighborhood Hits	254
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA5_MOUSE
NC score	0.591326 (rank : 7)	θ value	4.30538e-10 (rank : 40)
Query Neighborhood Hits	525	Target Neighborhood Hits	828	Shared Neighborhood Hits	281
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC3_MOUSE
NC score	0.589703 (rank : 8)	θ value	2.52405e-10 (rank : 38)
Query Neighborhood Hits	525	Target Neighborhood Hits	624	Shared Neighborhood Hits	237
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

NTNG1_MOUSE
NC score	0.589600 (rank : 9)	θ value	8.67504e-11 (rank : 32)
Query Neighborhood Hits	525	Target Neighborhood Hits	246	Shared Neighborhood Hits	194
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_HUMAN
NC score	0.588642 (rank : 10)	θ value	6.64225e-11 (rank : 29)
Query Neighborhood Hits	525	Target Neighborhood Hits	247	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LAMB2_HUMAN
NC score	0.588340 (rank : 11)	θ value	2.69671e-12 (rank : 18)
Query Neighborhood Hits	525	Target Neighborhood Hits	692	Shared Neighborhood Hits	249
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
NC score	0.586888 (rank : 12)	θ value	1.58096e-12 (rank : 15)
Query Neighborhood Hits	525	Target Neighborhood Hits	722	Shared Neighborhood Hits	241
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

NTNG2_HUMAN
NC score	0.586428 (rank : 13)	θ value	2.36244e-08 (rank : 53)
Query Neighborhood Hits	525	Target Neighborhood Hits	276	Shared Neighborhood Hits	212
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMA5_HUMAN
NC score	0.585152 (rank : 14)	θ value	1.25267e-09 (rank : 43)
Query Neighborhood Hits	525	Target Neighborhood Hits	976	Shared Neighborhood Hits	287
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MEGF9_MOUSE
NC score	0.581521 (rank : 15)	θ value	1.133e-10 (rank : 33)
Query Neighborhood Hits	525	Target Neighborhood Hits	896	Shared Neighborhood Hits	221
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMA1_HUMAN
NC score	0.581201 (rank : 16)	θ value	1.29331e-14 (rank : 5)
Query Neighborhood Hits	525	Target Neighborhood Hits	804	Shared Neighborhood Hits	264
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NTNG2_MOUSE
NC score	0.579691 (rank : 17)	θ value	1.99992e-07 (rank : 64)
Query Neighborhood Hits	525	Target Neighborhood Hits	276	Shared Neighborhood Hits	216
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMA1_MOUSE
NC score	0.577815 (rank : 18)	θ value	2.98157e-11 (rank : 27)
Query Neighborhood Hits	525	Target Neighborhood Hits	838	Shared Neighborhood Hits	266
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB3_MOUSE
NC score	0.576457 (rank : 19)	θ value	6.87365e-08 (rank : 55)
Query Neighborhood Hits	525	Target Neighborhood Hits	444	Shared Neighborhood Hits	208
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMB3_HUMAN
NC score	0.567125 (rank : 20)	θ value	1.53129e-07 (rank : 59)
Query Neighborhood Hits	525	Target Neighborhood Hits	461	Shared Neighborhood Hits	190
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMC2_MOUSE
NC score	0.564902 (rank : 21)	θ value	1.06045e-08 (rank : 49)
Query Neighborhood Hits	525	Target Neighborhood Hits	614	Shared Neighborhood Hits	238
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

SREC2_MOUSE
NC score	0.564698 (rank : 22)	θ value	3.64472e-09 (rank : 47)
Query Neighborhood Hits	525	Target Neighborhood Hits	605	Shared Neighborhood Hits	271
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

LAMC1_MOUSE
NC score	0.561542 (rank : 23)	θ value	1.58096e-12 (rank : 16)
Query Neighborhood Hits	525	Target Neighborhood Hits	856	Shared Neighborhood Hits	242
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SREC2_HUMAN
NC score	0.560214 (rank : 24)	θ value	1.80886e-08 (rank : 51)
Query Neighborhood Hits	525	Target Neighborhood Hits	645	Shared Neighborhood Hits	270
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LAMB1_MOUSE
NC score	0.559056 (rank : 25)	θ value	2.28291e-11 (rank : 24)
Query Neighborhood Hits	525	Target Neighborhood Hits	919	Shared Neighborhood Hits	238
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMA3_MOUSE
NC score	0.552630 (rank : 26)	θ value	1.02475e-11 (rank : 21)
Query Neighborhood Hits	525	Target Neighborhood Hits	859	Shared Neighborhood Hits	252
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMC2_HUMAN
NC score	0.550313 (rank : 27)	θ value	7.34386e-10 (rank : 42)
Query Neighborhood Hits	525	Target Neighborhood Hits	715	Shared Neighborhood Hits	240
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMA2_HUMAN
NC score	0.547727 (rank : 28)	θ value	3.76295e-14 (rank : 6)
Query Neighborhood Hits	525	Target Neighborhood Hits	1092	Shared Neighborhood Hits	265
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NET2_MOUSE
NC score	0.547417 (rank : 29)	θ value	3.64472e-09 (rank : 46)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	145
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET2_HUMAN
NC score	0.546061 (rank : 30)	θ value	3.64472e-09 (rank : 45)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	143
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

CUBN_HUMAN
NC score	0.545147 (rank : 31)	θ value	8.67504e-11 (rank : 31)
Query Neighborhood Hits	525	Target Neighborhood Hits	482	Shared Neighborhood Hits	292
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

LAMC1_HUMAN
NC score	0.543240 (rank : 32)	θ value	1.2105e-12 (rank : 14)
Query Neighborhood Hits	525	Target Neighborhood Hits	922	Shared Neighborhood Hits	236
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NET4_HUMAN
NC score	0.542263 (rank : 33)	θ value	1.17247e-07 (rank : 58)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	151
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
NC score	0.541343 (rank : 34)	θ value	1.99992e-07 (rank : 62)
Query Neighborhood Hits	525	Target Neighborhood Hits	180	Shared Neighborhood Hits	146
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

SREC_HUMAN
NC score	0.540111 (rank : 35)	θ value	7.1131e-05 (rank : 116)
Query Neighborhood Hits	525	Target Neighborhood Hits	645	Shared Neighborhood Hits	275
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LAMB1_HUMAN
NC score	0.532315 (rank : 36)	θ value	2.36244e-08 (rank : 52)
Query Neighborhood Hits	525	Target Neighborhood Hits	1018	Shared Neighborhood Hits	251
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMA2_MOUSE
NC score	0.528249 (rank : 37)	θ value	6.41864e-14 (rank : 8)
Query Neighborhood Hits	525	Target Neighborhood Hits	1198	Shared Neighborhood Hits	274
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CUBN_MOUSE
NC score	0.527724 (rank : 38)	θ value	4.76016e-09 (rank : 48)
Query Neighborhood Hits	525	Target Neighborhood Hits	477	Shared Neighborhood Hits	293
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

NET1_HUMAN
NC score	0.521722 (rank : 39)	θ value	1.99992e-07 (rank : 61)
Query Neighborhood Hits	525	Target Neighborhood Hits	149	Shared Neighborhood Hits	120
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
NC score	0.520780 (rank : 40)	θ value	8.97725e-08 (rank : 57)
Query Neighborhood Hits	525	Target Neighborhood Hits	151	Shared Neighborhood Hits	117
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

LAMA4_MOUSE
NC score	0.518152 (rank : 41)	θ value	2.98157e-11 (rank : 28)
Query Neighborhood Hits	525	Target Neighborhood Hits	584	Shared Neighborhood Hits	190
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA3_HUMAN
NC score	0.513000 (rank : 42)	θ value	7.09661e-13 (rank : 11)
Query Neighborhood Hits	525	Target Neighborhood Hits	760	Shared Neighborhood Hits	218
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

USH2A_MOUSE
NC score	0.512545 (rank : 43)	θ value	1.9326e-10 (rank : 37)
Query Neighborhood Hits	525	Target Neighborhood Hits	626	Shared Neighborhood Hits	238
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

USH2A_HUMAN
NC score	0.507136 (rank : 44)	θ value	1.02475e-11 (rank : 22)
Query Neighborhood Hits	525	Target Neighborhood Hits	600	Shared Neighborhood Hits	236
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

MEGF6_HUMAN
NC score	0.505731 (rank : 45)	θ value	4.45536e-07 (rank : 67)
Query Neighborhood Hits	525	Target Neighborhood Hits	671	Shared Neighborhood Hits	301
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

AGRIN_HUMAN
NC score	0.500651 (rank : 46)	θ value	0.000786445 (rank : 136)
Query Neighborhood Hits	525	Target Neighborhood Hits	582	Shared Neighborhood Hits	267
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

WIF1_MOUSE
NC score	0.495160 (rank : 47)	θ value	0.000602161 (rank : 135)
Query Neighborhood Hits	525	Target Neighborhood Hits	393	Shared Neighborhood Hits	266
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_HUMAN
NC score	0.494259 (rank : 48)	θ value	0.000158464 (rank : 123)
Query Neighborhood Hits	525	Target Neighborhood Hits	392	Shared Neighborhood Hits	272
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

NAGPA_MOUSE
NC score	0.489076 (rank : 49)	θ value	1.87187e-05 (rank : 100)
Query Neighborhood Hits	525	Target Neighborhood Hits	308	Shared Neighborhood Hits	220
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LAMA4_HUMAN
NC score	0.482292 (rank : 50)	θ value	5.26297e-08 (rank : 54)
Query Neighborhood Hits	525	Target Neighborhood Hits	708	Shared Neighborhood Hits	193
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

DLL4_MOUSE
NC score	0.476328 (rank : 51)	θ value	4.1701e-05 (rank : 105)
Query Neighborhood Hits	525	Target Neighborhood Hits	440	Shared Neighborhood Hits	271
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NAGPA_HUMAN
NC score	0.476189 (rank : 52)	θ value	0.000786445 (rank : 140)
Query Neighborhood Hits	525	Target Neighborhood Hits	282	Shared Neighborhood Hits	211
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

JAG1_MOUSE
NC score	0.474836 (rank : 53)	θ value	1.69304e-06 (rank : 76)
Query Neighborhood Hits	525	Target Neighborhood Hits	518	Shared Neighborhood Hits	287
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG1_HUMAN
NC score	0.473987 (rank : 54)	θ value	8.40245e-06 (rank : 94)
Query Neighborhood Hits	525	Target Neighborhood Hits	514	Shared Neighborhood Hits	291
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

DLL4_HUMAN
NC score	0.473610 (rank : 55)	θ value	0.000121331 (rank : 119)
Query Neighborhood Hits	525	Target Neighborhood Hits	435	Shared Neighborhood Hits	271
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

JAG2_MOUSE
NC score	0.466679 (rank : 56)	θ value	5.44631e-05 (rank : 108)
Query Neighborhood Hits	525	Target Neighborhood Hits	504	Shared Neighborhood Hits	282
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

DLK_HUMAN
NC score	0.466345 (rank : 57)	θ value	0.279714 (rank : 306)
Query Neighborhood Hits	525	Target Neighborhood Hits	401	Shared Neighborhood Hits	273
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

STAB2_HUMAN
NC score	0.465977 (rank : 58)	θ value	1.29631e-06 (rank : 75)
Query Neighborhood Hits	525	Target Neighborhood Hits	534	Shared Neighborhood Hits	277
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB1_HUMAN
NC score	0.465464 (rank : 59)	θ value	5.44631e-05 (rank : 112)
Query Neighborhood Hits	525	Target Neighborhood Hits	546	Shared Neighborhood Hits	284
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

JAG2_HUMAN
NC score	0.463603 (rank : 60)	θ value	9.29e-05 (rank : 117)
Query Neighborhood Hits	525	Target Neighborhood Hits	491	Shared Neighborhood Hits	279
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

DLL1_HUMAN
NC score	0.462715 (rank : 61)	θ value	0.0961366 (rank : 262)
Query Neighborhood Hits	525	Target Neighborhood Hits	455	Shared Neighborhood Hits	283
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

STAB1_MOUSE
NC score	0.461677 (rank : 62)	θ value	9.29e-05 (rank : 118)
Query Neighborhood Hits	525	Target Neighborhood Hits	566	Shared Neighborhood Hits	286
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_MOUSE
NC score	0.460386 (rank : 63)	θ value	2.88788e-06 (rank : 82)
Query Neighborhood Hits	525	Target Neighborhood Hits	528	Shared Neighborhood Hits	283
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

DLK_MOUSE
NC score	0.459484 (rank : 64)	θ value	0.125558 (rank : 273)
Query Neighborhood Hits	525	Target Neighborhood Hits	374	Shared Neighborhood Hits	264
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_MOUSE
NC score	0.459182 (rank : 65)	θ value	0.0563607 (rank : 237)
Query Neighborhood Hits	525	Target Neighborhood Hits	456	Shared Neighborhood Hits	285
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
NC score	0.456418 (rank : 66)	θ value	0.0148317 (rank : 194)
Query Neighborhood Hits	525	Target Neighborhood Hits	419	Shared Neighborhood Hits	259
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DNER_HUMAN
NC score	0.454574 (rank : 67)	θ value	0.0148317 (rank : 195)
Query Neighborhood Hits	525	Target Neighborhood Hits	460	Shared Neighborhood Hits	266
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

KRA53_HUMAN
NC score	0.454151 (rank : 68)	θ value	0.279714 (rank : 310)
Query Neighborhood Hits	525	Target Neighborhood Hits	331	Shared Neighborhood Hits	185
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

DLL3_MOUSE
NC score	0.452406 (rank : 69)	θ value	0.0330416 (rank : 218)
Query Neighborhood Hits	525	Target Neighborhood Hits	399	Shared Neighborhood Hits	259
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DNER_MOUSE
NC score	0.452215 (rank : 70)	θ value	0.0961366 (rank : 263)
Query Neighborhood Hits	525	Target Neighborhood Hits	413	Shared Neighborhood Hits	259
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

KRA51_HUMAN
NC score	0.450213 (rank : 71)	θ value	8.99809 (rank : 516)
Query Neighborhood Hits	525	Target Neighborhood Hits	288	Shared Neighborhood Hits	170
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

CRUM2_HUMAN
NC score	0.448216 (rank : 72)	θ value	0.00665767 (rank : 175)
Query Neighborhood Hits	525	Target Neighborhood Hits	453	Shared Neighborhood Hits	272
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CRUM1_HUMAN
NC score	0.446225 (rank : 73)	θ value	0.125558 (rank : 272)
Query Neighborhood Hits	525	Target Neighborhood Hits	457	Shared Neighborhood Hits	277
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

NOTC1_MOUSE
NC score	0.444143 (rank : 74)	θ value	1.69304e-06 (rank : 77)
Query Neighborhood Hits	525	Target Neighborhood Hits	916	Shared Neighborhood Hits	296
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

EGFL9_HUMAN
NC score	0.443639 (rank : 75)	θ value	0.813845 (rank : 348)
Query Neighborhood Hits	525	Target Neighborhood Hits	365	Shared Neighborhood Hits	252
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

KRA58_HUMAN
NC score	0.443093 (rank : 76)	θ value	0.0563607 (rank : 240)
Query Neighborhood Hits	525	Target Neighborhood Hits	324	Shared Neighborhood Hits	181
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

CRUM1_MOUSE
NC score	0.442705 (rank : 77)	θ value	0.163984 (rank : 288)
Query Neighborhood Hits	525	Target Neighborhood Hits	444	Shared Neighborhood Hits	273
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

EGFL9_MOUSE
NC score	0.440039 (rank : 78)	θ value	0.365318 (rank : 316)
Query Neighborhood Hits	525	Target Neighborhood Hits	379	Shared Neighborhood Hits	254
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

NOTC1_HUMAN
NC score	0.439469 (rank : 79)	θ value	5.62301e-10 (rank : 41)
Query Neighborhood Hits	525	Target Neighborhood Hits	906	Shared Neighborhood Hits	297
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KRA59_HUMAN
NC score	0.436231 (rank : 80)	θ value	0.125558 (rank : 282)
Query Neighborhood Hits	525	Target Neighborhood Hits	310	Shared Neighborhood Hits	167
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA55_HUMAN
NC score	0.435851 (rank : 81)	θ value	0.163984 (rank : 293)
Query Neighborhood Hits	525	Target Neighborhood Hits	257	Shared Neighborhood Hits	160
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

NOTC3_MOUSE
NC score	0.430199 (rank : 82)	θ value	4.92598e-06 (rank : 87)
Query Neighborhood Hits	525	Target Neighborhood Hits	975	Shared Neighborhood Hits	305
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.427616 (rank : 83)	θ value	3.19293e-05 (rank : 104)
Query Neighborhood Hits	525	Target Neighborhood Hits	1062	Shared Neighborhood Hits	301
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_MOUSE
NC score	0.421865 (rank : 84)	θ value	9.92553e-07 (rank : 74)
Query Neighborhood Hits	525	Target Neighborhood Hits	1069	Shared Neighborhood Hits	297
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
NC score	0.417792 (rank : 85)	θ value	1.99992e-07 (rank : 63)
Query Neighborhood Hits	525	Target Neighborhood Hits	1113	Shared Neighborhood Hits	302
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KRA54_HUMAN
NC score	0.416286 (rank : 86)	θ value	0.0961366 (rank : 266)
Query Neighborhood Hits	525	Target Neighborhood Hits	270	Shared Neighborhood Hits	154
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

NOTC4_MOUSE
NC score	0.415921 (rank : 87)	θ value	3.41135e-07 (rank : 66)
Query Neighborhood Hits	525	Target Neighborhood Hits	872	Shared Neighborhood Hits	296
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

KRA57_HUMAN
NC score	0.415719 (rank : 88)	θ value	2.36792 (rank : 418)
Query Neighborhood Hits	525	Target Neighborhood Hits	269	Shared Neighborhood Hits	162
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

NOTC4_HUMAN
NC score	0.415032 (rank : 89)	θ value	8.40245e-06 (rank : 97)
Query Neighborhood Hits	525	Target Neighborhood Hits	905	Shared Neighborhood Hits	303
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TENX_HUMAN
NC score	0.413688 (rank : 90)	θ value	1.69304e-06 (rank : 79)
Query Neighborhood Hits	525	Target Neighborhood Hits	789	Shared Neighborhood Hits	284
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TENA_MOUSE
NC score	0.407418 (rank : 91)	θ value	2.88788e-06 (rank : 83)
Query Neighborhood Hits	525	Target Neighborhood Hits	596	Shared Neighborhood Hits	266
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

PGBM_MOUSE
NC score	0.406629 (rank : 92)	θ value	1.9326e-10 (rank : 36)
Query Neighborhood Hits	525	Target Neighborhood Hits	1073	Shared Neighborhood Hits	289
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

KRA56_HUMAN
NC score	0.404632 (rank : 93)	θ value	0.813845 (rank : 353)
Query Neighborhood Hits	525	Target Neighborhood Hits	207	Shared Neighborhood Hits	132
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

TENA_HUMAN
NC score	0.403742 (rank : 94)	θ value	0.00035302 (rank : 131)
Query Neighborhood Hits	525	Target Neighborhood Hits	631	Shared Neighborhood Hits	270
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

PGBM_HUMAN
NC score	0.395050 (rank : 95)	θ value	1.9326e-10 (rank : 35)
Query Neighborhood Hits	525	Target Neighborhood Hits	1113	Shared Neighborhood Hits	284
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TLL1_MOUSE
NC score	0.390612 (rank : 96)	θ value	7.09661e-13 (rank : 12)
Query Neighborhood Hits	525	Target Neighborhood Hits	237	Shared Neighborhood Hits	139
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

CREL1_HUMAN
NC score	0.389539 (rank : 97)	θ value	0.0736092 (rank : 244)
Query Neighborhood Hits	525	Target Neighborhood Hits	441	Shared Neighborhood Hits	212
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

BMP1_MOUSE
NC score	0.389319 (rank : 98)	θ value	6.41864e-14 (rank : 7)
Query Neighborhood Hits	525	Target Neighborhood Hits	236	Shared Neighborhood Hits	141
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_HUMAN
NC score	0.388208 (rank : 99)	θ value	1.86753e-13 (rank : 9)
Query Neighborhood Hits	525	Target Neighborhood Hits	233	Shared Neighborhood Hits	140
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL1_HUMAN
NC score	0.387656 (rank : 100)	θ value	1.58096e-12 (rank : 17)
Query Neighborhood Hits	525	Target Neighborhood Hits	236	Shared Neighborhood Hits	137
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

EGFL7_HUMAN
NC score	0.385938 (rank : 101)	θ value	0.00102713 (rank : 142)
Query Neighborhood Hits	525	Target Neighborhood Hits	325	Shared Neighborhood Hits	226
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

TLL2_HUMAN
NC score	0.383718 (rank : 102)	θ value	3.52202e-12 (rank : 19)
Query Neighborhood Hits	525	Target Neighborhood Hits	241	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

LTBP4_MOUSE
NC score	0.382788 (rank : 103)	θ value	0.0563607 (rank : 242)
Query Neighborhood Hits	525	Target Neighborhood Hits	607	Shared Neighborhood Hits	266
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

KR511_HUMAN
NC score	0.382525 (rank : 104)	θ value	1.81305 (rank : 403)
Query Neighborhood Hits	525	Target Neighborhood Hits	231	Shared Neighborhood Hits	134
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

FBN3_HUMAN
NC score	0.381053 (rank : 105)	θ value	0.0113563 (rank : 188)
Query Neighborhood Hits	525	Target Neighborhood Hits	543	Shared Neighborhood Hits	283
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

TLL2_MOUSE
NC score	0.380741 (rank : 106)	θ value	9.26847e-13 (rank : 13)
Query Neighborhood Hits	525	Target Neighborhood Hits	240	Shared Neighborhood Hits	140
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

FBN1_MOUSE
NC score	0.377887 (rank : 107)	θ value	0.0193708 (rank : 201)
Query Neighborhood Hits	525	Target Neighborhood Hits	563	Shared Neighborhood Hits	284
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

HHIP_HUMAN
NC score	0.377179 (rank : 108)	θ value	0.0736092 (rank : 246)
Query Neighborhood Hits	525	Target Neighborhood Hits	249	Shared Neighborhood Hits	204
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

FBN1_HUMAN
NC score	0.375515 (rank : 109)	θ value	0.125558 (rank : 275)
Query Neighborhood Hits	525	Target Neighborhood Hits	557	Shared Neighborhood Hits	284
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

CREL1_MOUSE
NC score	0.375242 (rank : 110)	θ value	0.0736092 (rank : 245)
Query Neighborhood Hits	525	Target Neighborhood Hits	524	Shared Neighborhood Hits	221
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

FBN2_MOUSE
NC score	0.373580 (rank : 111)	θ value	0.125558 (rank : 276)
Query Neighborhood Hits	525	Target Neighborhood Hits	549	Shared Neighborhood Hits	290
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_HUMAN
NC score	0.373277 (rank : 112)	θ value	0.0961366 (rank : 264)
Query Neighborhood Hits	525	Target Neighborhood Hits	560	Shared Neighborhood Hits	288
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

NELL1_HUMAN
NC score	0.370772 (rank : 113)	θ value	1.06291 (rank : 373)
Query Neighborhood Hits	525	Target Neighborhood Hits	451	Shared Neighborhood Hits	268
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

HHIP_MOUSE
NC score	0.369385 (rank : 114)	θ value	0.0252991 (rank : 207)
Query Neighborhood Hits	525	Target Neighborhood Hits	219	Shared Neighborhood Hits	185
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

LTBP2_MOUSE
NC score	0.369353 (rank : 115)	θ value	0.0961366 (rank : 269)
Query Neighborhood Hits	525	Target Neighborhood Hits	617	Shared Neighborhood Hits	272
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

KRA52_HUMAN
NC score	0.369279 (rank : 116)	θ value	3.0926 (rank : 433)
Query Neighborhood Hits	525	Target Neighborhood Hits	236	Shared Neighborhood Hits	141
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

EGFL7_MOUSE
NC score	0.369234 (rank : 117)	θ value	0.00390308 (rank : 164)
Query Neighborhood Hits	525	Target Neighborhood Hits	287	Shared Neighborhood Hits	211
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

SCUB3_MOUSE
NC score	0.368084 (rank : 118)	θ value	1.06291 (rank : 377)
Query Neighborhood Hits	525	Target Neighborhood Hits	442	Shared Neighborhood Hits	258
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.367880 (rank : 119)	θ value	1.81305 (rank : 409)
Query Neighborhood Hits	525	Target Neighborhood Hits	428	Shared Neighborhood Hits	251
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LTBP2_HUMAN
NC score	0.367103 (rank : 120)	θ value	0.0961366 (rank : 268)
Query Neighborhood Hits	525	Target Neighborhood Hits	552	Shared Neighborhood Hits	280
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_MOUSE
NC score	0.362544 (rank : 121)	θ value	0.00390308 (rank : 167)
Query Neighborhood Hits	525	Target Neighborhood Hits	475	Shared Neighborhood Hits	270
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

ITB6_HUMAN
NC score	0.360697 (rank : 122)	θ value	0.00228821 (rank : 153)
Query Neighborhood Hits	525	Target Neighborhood Hits	318	Shared Neighborhood Hits	219
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

KLDC3_MOUSE
NC score	0.359676 (rank : 123)	θ value	7.09661e-13 (rank : 10)
Query Neighborhood Hits	525	Target Neighborhood Hits	77	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VEM9, Q3TCN9, Q3UR95, Q91XU6, Q99JH9, Q9DBG8	Gene names	Klhdc3, Peas
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein).

LRP1B_HUMAN
NC score	0.358569 (rank : 124)	θ value	7.59969e-07 (rank : 72)
Query Neighborhood Hits	525	Target Neighborhood Hits	602	Shared Neighborhood Hits	300
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

ITB6_MOUSE
NC score	0.358456 (rank : 125)	θ value	0.0563607 (rank : 239)
Query Neighborhood Hits	525	Target Neighborhood Hits	341	Shared Neighborhood Hits	232
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

LTBP3_HUMAN
NC score	0.357753 (rank : 126)	θ value	0.00298849 (rank : 159)
Query Neighborhood Hits	525	Target Neighborhood Hits	502	Shared Neighborhood Hits	266
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

ITB5_MOUSE
NC score	0.356646 (rank : 127)	θ value	0.00390308 (rank : 166)
Query Neighborhood Hits	525	Target Neighborhood Hits	329	Shared Neighborhood Hits	228
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB7_MOUSE
NC score	0.355508 (rank : 128)	θ value	0.0252991 (rank : 210)
Query Neighborhood Hits	525	Target Neighborhood Hits	277	Shared Neighborhood Hits	213
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

LRP1B_MOUSE
NC score	0.355019 (rank : 129)	θ value	8.40245e-06 (rank : 95)
Query Neighborhood Hits	525	Target Neighborhood Hits	606	Shared Neighborhood Hits	299
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

ITB7_HUMAN
NC score	0.354683 (rank : 130)	θ value	0.0148317 (rank : 198)
Query Neighborhood Hits	525	Target Neighborhood Hits	290	Shared Neighborhood Hits	219
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

NELL2_HUMAN
NC score	0.352282 (rank : 131)	θ value	5.27518 (rank : 478)
Query Neighborhood Hits	525	Target Neighborhood Hits	449	Shared Neighborhood Hits	265
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

LRP1_HUMAN
NC score	0.351743 (rank : 132)	θ value	0.00869519 (rank : 184)
Query Neighborhood Hits	525	Target Neighborhood Hits	617	Shared Neighborhood Hits	302
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

KLDC3_HUMAN
NC score	0.351625 (rank : 133)	θ value	2.98157e-11 (rank : 26)
Query Neighborhood Hits	525	Target Neighborhood Hits	76	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BQ90	Gene names	KLHDC3, PEAS
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein).

NELL2_MOUSE
NC score	0.350689 (rank : 134)	θ value	6.88961 (rank : 494)
Query Neighborhood Hits	525	Target Neighborhood Hits	436	Shared Neighborhood Hits	262
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

EDIL3_MOUSE
NC score	0.350078 (rank : 135)	θ value	0.62314 (rank : 334)
Query Neighborhood Hits	525	Target Neighborhood Hits	317	Shared Neighborhood Hits	222
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

ITB5_HUMAN
NC score	0.347728 (rank : 136)	θ value	0.0252991 (rank : 209)
Query Neighborhood Hits	525	Target Neighborhood Hits	310	Shared Neighborhood Hits	215
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

NETO1_MOUSE
NC score	0.347298 (rank : 137)	θ value	9.92553e-07 (rank : 73)
Query Neighborhood Hits	525	Target Neighborhood Hits	109	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

KR510_HUMAN
NC score	0.347188 (rank : 138)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	525	Target Neighborhood Hits	217	Shared Neighborhood Hits	125
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

NETO1_HUMAN
NC score	0.343663 (rank : 139)	θ value	4.92598e-06 (rank : 86)
Query Neighborhood Hits	525	Target Neighborhood Hits	110	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

CSPG3_HUMAN
NC score	0.343436 (rank : 140)	θ value	0.0193708 (rank : 200)
Query Neighborhood Hits	525	Target Neighborhood Hits	676	Shared Neighborhood Hits	262
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
NC score	0.340893 (rank : 141)	θ value	3.0926 (rank : 431)
Query Neighborhood Hits	525	Target Neighborhood Hits	657	Shared Neighborhood Hits	269
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ITB1_HUMAN
NC score	0.340245 (rank : 142)	θ value	0.00665767 (rank : 176)
Query Neighborhood Hits	525	Target Neighborhood Hits	298	Shared Neighborhood Hits	217
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KR171_HUMAN
NC score	0.340108 (rank : 143)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	525	Target Neighborhood Hits	144	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

NETO2_HUMAN
NC score	0.339519 (rank : 144)	θ value	8.40245e-06 (rank : 96)
Query Neighborhood Hits	525	Target Neighborhood Hits	109	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

ITB2_MOUSE
NC score	0.339369 (rank : 145)	θ value	8.99809 (rank : 510)
Query Neighborhood Hits	525	Target Neighborhood Hits	326	Shared Neighborhood Hits	220
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

LTB1S_HUMAN
NC score	0.337217 (rank : 146)	θ value	0.125558 (rank : 284)
Query Neighborhood Hits	525	Target Neighborhood Hits	502	Shared Neighborhood Hits	259
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
NC score	0.336501 (rank : 147)	θ value	0.125558 (rank : 283)
Query Neighborhood Hits	525	Target Neighborhood Hits	514	Shared Neighborhood Hits	266
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ITB1_MOUSE
NC score	0.336220 (rank : 148)	θ value	0.0252991 (rank : 208)
Query Neighborhood Hits	525	Target Neighborhood Hits	283	Shared Neighborhood Hits	212
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB3_MOUSE
NC score	0.335458 (rank : 149)	θ value	0.0330416 (rank : 221)
Query Neighborhood Hits	525	Target Neighborhood Hits	319	Shared Neighborhood Hits	216
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

LTB1S_MOUSE
NC score	0.334781 (rank : 150)	θ value	0.125558 (rank : 285)
Query Neighborhood Hits	525	Target Neighborhood Hits	479	Shared Neighborhood Hits	253
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ITB3_HUMAN
NC score	0.334693 (rank : 151)	θ value	0.21417 (rank : 299)
Query Neighborhood Hits	525	Target Neighborhood Hits	325	Shared Neighborhood Hits	221
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

NETO2_MOUSE
NC score	0.333218 (rank : 152)	θ value	0.000121331 (rank : 121)
Query Neighborhood Hits	525	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

LTB1L_HUMAN
NC score	0.332906 (rank : 153)	θ value	3.0926 (rank : 435)
Query Neighborhood Hits	525	Target Neighborhood Hits	553	Shared Neighborhood Hits	260
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SLIT1_MOUSE
NC score	0.332488 (rank : 154)	θ value	0.000786445 (rank : 141)
Query Neighborhood Hits	525	Target Neighborhood Hits	715	Shared Neighborhood Hits	265
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT1_HUMAN
NC score	0.332190 (rank : 155)	θ value	0.00134147 (rank : 150)
Query Neighborhood Hits	525	Target Neighborhood Hits	700	Shared Neighborhood Hits	262
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

CSPG2_MOUSE
NC score	0.332026 (rank : 156)	θ value	0.163984 (rank : 289)
Query Neighborhood Hits	525	Target Neighborhood Hits	711	Shared Neighborhood Hits	272
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

PCOC2_MOUSE
NC score	0.331837 (rank : 157)	θ value	5.44631e-05 (rank : 110)
Query Neighborhood Hits	525	Target Neighborhood Hits	73	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

CSPG2_HUMAN
NC score	0.330836 (rank : 158)	θ value	0.0961366 (rank : 261)
Query Neighborhood Hits	525	Target Neighborhood Hits	681	Shared Neighborhood Hits	267
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

ITB4_HUMAN
NC score	0.328476 (rank : 159)	θ value	0.00869519 (rank : 181)
Query Neighborhood Hits	525	Target Neighborhood Hits	458	Shared Neighborhood Hits	221
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB2_HUMAN
NC score	0.327980 (rank : 160)	θ value	0.365318 (rank : 318)
Query Neighborhood Hits	525	Target Neighborhood Hits	282	Shared Neighborhood Hits	199
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

EDIL3_HUMAN
NC score	0.327863 (rank : 161)	θ value	0.47712 (rank : 328)
Query Neighborhood Hits	525	Target Neighborhood Hits	292	Shared Neighborhood Hits	204
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

PCOC2_HUMAN
NC score	0.327829 (rank : 162)	θ value	0.000158464 (rank : 122)
Query Neighborhood Hits	525	Target Neighborhood Hits	73	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

TSG6_MOUSE
NC score	0.323323 (rank : 163)	θ value	0.00175202 (rank : 151)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	64
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

PROS_HUMAN
NC score	0.323044 (rank : 164)	θ value	1.38821 (rank : 394)
Query Neighborhood Hits	525	Target Neighborhood Hits	340	Shared Neighborhood Hits	221
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

TSG6_HUMAN
NC score	0.322909 (rank : 165)	θ value	0.00665767 (rank : 180)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	64
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

ZAN_MOUSE
NC score	0.322718 (rank : 166)	θ value	4.03905 (rank : 465)
Query Neighborhood Hits	525	Target Neighborhood Hits	808	Shared Neighborhood Hits	298
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

EGFL8_MOUSE
NC score	0.321934 (rank : 167)	θ value	0.0148317 (rank : 196)
Query Neighborhood Hits	525	Target Neighborhood Hits	266	Shared Neighborhood Hits	185
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

LYAM2_MOUSE
NC score	0.321297 (rank : 168)	θ value	0.00390308 (rank : 168)
Query Neighborhood Hits	525	Target Neighborhood Hits	420	Shared Neighborhood Hits	247
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

EGFL8_HUMAN
NC score	0.321218 (rank : 169)	θ value	0.125558 (rank : 274)
Query Neighborhood Hits	525	Target Neighborhood Hits	270	Shared Neighborhood Hits	179
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

SLIT2_HUMAN
NC score	0.319790 (rank : 170)	θ value	0.00298849 (rank : 161)
Query Neighborhood Hits	525	Target Neighborhood Hits	708	Shared Neighborhood Hits	267
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

KR106_HUMAN
NC score	0.319655 (rank : 171)	θ value	0.0330416 (rank : 223)
Query Neighborhood Hits	525	Target Neighborhood Hits	347	Shared Neighborhood Hits	183
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
NC score	0.319490 (rank : 172)	θ value	1.06291 (rank : 371)
Query Neighborhood Hits	525	Target Neighborhood Hits	330	Shared Neighborhood Hits	181
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR104_HUMAN
NC score	0.318587 (rank : 173)	θ value	0.813845 (rank : 352)
Query Neighborhood Hits	525	Target Neighborhood Hits	313	Shared Neighborhood Hits	162
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

TENR_MOUSE
NC score	0.318367 (rank : 174)	θ value	6.43352e-06 (rank : 91)
Query Neighborhood Hits	525	Target Neighborhood Hits	531	Shared Neighborhood Hits	243
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

MFRP_HUMAN
NC score	0.315800 (rank : 175)	θ value	1.43324e-05 (rank : 99)
Query Neighborhood Hits	525	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

PCOC1_MOUSE
NC score	0.313514 (rank : 176)	θ value	0.0113563 (rank : 192)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

SLIT2_MOUSE
NC score	0.312771 (rank : 177)	θ value	0.00665767 (rank : 179)
Query Neighborhood Hits	525	Target Neighborhood Hits	684	Shared Neighborhood Hits	249
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

GAS6_HUMAN
NC score	0.312135 (rank : 178)	θ value	4.03905 (rank : 449)
Query Neighborhood Hits	525	Target Neighborhood Hits	348	Shared Neighborhood Hits	218
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

TENR_HUMAN
NC score	0.312012 (rank : 179)	θ value	1.87187e-05 (rank : 101)
Query Neighborhood Hits	525	Target Neighborhood Hits	526	Shared Neighborhood Hits	242
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

PROS_MOUSE
NC score	0.311832 (rank : 180)	θ value	1.38821 (rank : 395)
Query Neighborhood Hits	525	Target Neighborhood Hits	330	Shared Neighborhood Hits	222
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

CSMD2_HUMAN
NC score	0.311164 (rank : 181)	θ value	4.59992e-12 (rank : 20)
Query Neighborhood Hits	525	Target Neighborhood Hits	188	Shared Neighborhood Hits	82
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD1_MOUSE
NC score	0.309543 (rank : 182)	θ value	8.67504e-11 (rank : 30)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	94
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

PCSK5_MOUSE
NC score	0.309001 (rank : 183)	θ value	0.0330416 (rank : 226)
Query Neighborhood Hits	525	Target Neighborhood Hits	613	Shared Neighborhood Hits	246
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

COMP_MOUSE
NC score	0.308361 (rank : 184)	θ value	2.36792 (rank : 414)
Query Neighborhood Hits	525	Target Neighborhood Hits	290	Shared Neighborhood Hits	201
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

GAS6_MOUSE
NC score	0.308198 (rank : 185)	θ value	4.03905 (rank : 450)
Query Neighborhood Hits	525	Target Neighborhood Hits	343	Shared Neighborhood Hits	224
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

TSP4_MOUSE
NC score	0.308042 (rank : 186)	θ value	0.365318 (rank : 325)
Query Neighborhood Hits	525	Target Neighborhood Hits	276	Shared Neighborhood Hits	201
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

SLIT3_MOUSE
NC score	0.307157 (rank : 187)	θ value	0.0736092 (rank : 255)
Query Neighborhood Hits	525	Target Neighborhood Hits	700	Shared Neighborhood Hits	265
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TSP4_HUMAN
NC score	0.306394 (rank : 188)	θ value	0.163984 (rank : 295)
Query Neighborhood Hits	525	Target Neighborhood Hits	277	Shared Neighborhood Hits	194
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

CSMD1_HUMAN
NC score	0.305699 (rank : 189)	θ value	3.29651e-10 (rank : 39)
Query Neighborhood Hits	525	Target Neighborhood Hits	176	Shared Neighborhood Hits	88
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

SLIT3_HUMAN
NC score	0.305256 (rank : 190)	θ value	0.0736092 (rank : 254)
Query Neighborhood Hits	525	Target Neighborhood Hits	682	Shared Neighborhood Hits	256
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

CSMD3_HUMAN
NC score	0.304363 (rank : 191)	θ value	2.98157e-11 (rank : 25)
Query Neighborhood Hits	525	Target Neighborhood Hits	199	Shared Neighborhood Hits	91
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

LYAM2_HUMAN
NC score	0.303380 (rank : 192)	θ value	0.000461057 (rank : 134)
Query Neighborhood Hits	525	Target Neighborhood Hits	394	Shared Neighborhood Hits	231
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MFRP_MOUSE
NC score	0.302681 (rank : 193)	θ value	2.44474e-05 (rank : 102)
Query Neighborhood Hits	525	Target Neighborhood Hits	166	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

ITB8_HUMAN
NC score	0.300339 (rank : 194)	θ value	0.0431538 (rank : 231)
Query Neighborhood Hits	525	Target Neighborhood Hits	280	Shared Neighborhood Hits	211
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

LRP12_HUMAN
NC score	0.299208 (rank : 195)	θ value	0.00228821 (rank : 155)
Query Neighborhood Hits	525	Target Neighborhood Hits	205	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
NC score	0.298773 (rank : 196)	θ value	0.00035302 (rank : 129)
Query Neighborhood Hits	525	Target Neighborhood Hits	180	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

FBLN2_HUMAN
NC score	0.297836 (rank : 197)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	525	Target Neighborhood Hits	392	Shared Neighborhood Hits	204
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

TSP3_MOUSE
NC score	0.297322 (rank : 198)	θ value	0.0252991 (rank : 215)
Query Neighborhood Hits	525	Target Neighborhood Hits	247	Shared Neighborhood Hits	174
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

LYAM1_MOUSE
NC score	0.296450 (rank : 199)	θ value	0.0961366 (rank : 270)
Query Neighborhood Hits	525	Target Neighborhood Hits	332	Shared Neighborhood Hits	209
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

NRP2_HUMAN
NC score	0.296188 (rank : 200)	θ value	1.53129e-07 (rank : 60)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	60
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
NC score	0.295574 (rank : 201)	θ value	4.45536e-07 (rank : 68)
Query Neighborhood Hits	525	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

C1QR1_MOUSE
NC score	0.295090 (rank : 202)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	525	Target Neighborhood Hits	342	Shared Neighborhood Hits	215
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1QR1_HUMAN
NC score	0.293903 (rank : 203)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	525	Target Neighborhood Hits	493	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

LYAM1_HUMAN
NC score	0.293492 (rank : 204)	θ value	0.0113563 (rank : 191)
Query Neighborhood Hits	525	Target Neighborhood Hits	315	Shared Neighborhood Hits	195
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

FRAS1_HUMAN
NC score	0.293177 (rank : 205)	θ value	0.0961366 (rank : 265)
Query Neighborhood Hits	525	Target Neighborhood Hits	759	Shared Neighborhood Hits	234
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FBLN2_MOUSE
NC score	0.293104 (rank : 206)	θ value	2.36792 (rank : 416)
Query Neighborhood Hits	525	Target Neighborhood Hits	505	Shared Neighborhood Hits	219
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LYAM3_MOUSE
NC score	0.291548 (rank : 207)	θ value	0.0431538 (rank : 235)
Query Neighborhood Hits	525	Target Neighborhood Hits	390	Shared Neighborhood Hits	225
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LRP2_HUMAN
NC score	0.290716 (rank : 208)	θ value	2.36792 (rank : 419)
Query Neighborhood Hits	525	Target Neighborhood Hits	573	Shared Neighborhood Hits	290
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

NID2_HUMAN
NC score	0.290669 (rank : 209)	θ value	1.81305 (rank : 407)
Query Neighborhood Hits	525	Target Neighborhood Hits	456	Shared Neighborhood Hits	214
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

PCOC1_HUMAN
NC score	0.290029 (rank : 210)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	525	Target Neighborhood Hits	146	Shared Neighborhood Hits	55
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

TSP3_HUMAN
NC score	0.289688 (rank : 211)	θ value	0.0252991 (rank : 214)
Query Neighborhood Hits	525	Target Neighborhood Hits	250	Shared Neighborhood Hits	168
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

CRIM1_HUMAN
NC score	0.287734 (rank : 212)	θ value	6.88961 (rank : 486)
Query Neighborhood Hits	525	Target Neighborhood Hits	362	Shared Neighborhood Hits	180
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

FRAS1_MOUSE
NC score	0.287643 (rank : 213)	θ value	0.0148317 (rank : 197)
Query Neighborhood Hits	525	Target Neighborhood Hits	747	Shared Neighborhood Hits	231
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

COMP_HUMAN
NC score	0.286659 (rank : 214)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	525	Target Neighborhood Hits	258	Shared Neighborhood Hits	181
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NRP1_HUMAN
NC score	0.285431 (rank : 215)	θ value	1.69304e-06 (rank : 78)
Query Neighborhood Hits	525	Target Neighborhood Hits	119	Shared Neighborhood Hits	59
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
NC score	0.284460 (rank : 216)	θ value	2.88788e-06 (rank : 81)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	58
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

UROM_HUMAN
NC score	0.284124 (rank : 217)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	525	Target Neighborhood Hits	284	Shared Neighborhood Hits	199
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

FBLN1_MOUSE
NC score	0.281913 (rank : 218)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	525	Target Neighborhood Hits	329	Shared Neighborhood Hits	201
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

CUZD1_HUMAN
NC score	0.281048 (rank : 219)	θ value	0.00509761 (rank : 171)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

LYAM3_HUMAN
NC score	0.280565 (rank : 220)	θ value	1.38821 (rank : 389)
Query Neighborhood Hits	525	Target Neighborhood Hits	378	Shared Neighborhood Hits	222
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LZTR1_MOUSE
NC score	0.280052 (rank : 221)	θ value	2.79066e-09 (rank : 44)
Query Neighborhood Hits	525	Target Neighborhood Hits	200	Shared Neighborhood Hits	76
SwissProt Accessions	Q9CQ33	Gene names	Lztr1, Tcfl2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

EGF_MOUSE
NC score	0.279339 (rank : 222)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	525	Target Neighborhood Hits	358	Shared Neighborhood Hits	223
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

TENN_HUMAN
NC score	0.277085 (rank : 223)	θ value	0.00035302 (rank : 132)
Query Neighborhood Hits	525	Target Neighborhood Hits	453	Shared Neighborhood Hits	217
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

UROM_MOUSE
NC score	0.276415 (rank : 224)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	525	Target Neighborhood Hits	276	Shared Neighborhood Hits	196
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

NID1_HUMAN
NC score	0.275937 (rank : 225)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	525	Target Neighborhood Hits	329	Shared Neighborhood Hits	204
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

LZTR1_HUMAN
NC score	0.275800 (rank : 226)	θ value	1.38499e-08 (rank : 50)
Query Neighborhood Hits	525	Target Neighborhood Hits	196	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N653, Q14776	Gene names	LZTR1, TCFL2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

MFGM_MOUSE
NC score	0.275315 (rank : 227)	θ value	0.62314 (rank : 340)
Query Neighborhood Hits	525	Target Neighborhood Hits	233	Shared Neighborhood Hits	176
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

TRBM_HUMAN
NC score	0.275192 (rank : 228)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	525	Target Neighborhood Hits	339	Shared Neighborhood Hits	198
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

NID1_MOUSE
NC score	0.273853 (rank : 229)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	525	Target Neighborhood Hits	335	Shared Neighborhood Hits	203
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TENN_MOUSE
NC score	0.273790 (rank : 230)	θ value	0.00035302 (rank : 133)
Query Neighborhood Hits	525	Target Neighborhood Hits	484	Shared Neighborhood Hits	220
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CUZD1_MOUSE
NC score	0.273217 (rank : 231)	θ value	0.0330416 (rank : 217)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	50
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

FBLN1_HUMAN
NC score	0.272332 (rank : 232)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	525	Target Neighborhood Hits	324	Shared Neighborhood Hits	197
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

TRBM_MOUSE
NC score	0.271422 (rank : 233)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	525	Target Neighborhood Hits	361	Shared Neighborhood Hits	208
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

SUSD1_HUMAN
NC score	0.270174 (rank : 234)	θ value	6.88961 (rank : 501)
Query Neighborhood Hits	525	Target Neighborhood Hits	285	Shared Neighborhood Hits	169
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

NID2_MOUSE
NC score	0.269288 (rank : 235)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	525	Target Neighborhood Hits	338	Shared Neighborhood Hits	202
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

PGCB_HUMAN
NC score	0.268460 (rank : 236)	θ value	0.00035302 (rank : 130)
Query Neighborhood Hits	525	Target Neighborhood Hits	478	Shared Neighborhood Hits	208
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

KR101_HUMAN
NC score	0.267111 (rank : 237)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	525	Target Neighborhood Hits	261	Shared Neighborhood Hits	145
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

PGCB_MOUSE
NC score	0.266488 (rank : 238)	θ value	0.00298849 (rank : 160)
Query Neighborhood Hits	525	Target Neighborhood Hits	459	Shared Neighborhood Hits	210
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

KRA93_HUMAN
NC score	0.265747 (rank : 239)	θ value	0.0431538 (rank : 234)
Query Neighborhood Hits	525	Target Neighborhood Hits	203	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

LRP3_HUMAN
NC score	0.265722 (rank : 240)	θ value	1.38821 (rank : 388)
Query Neighborhood Hits	525	Target Neighborhood Hits	280	Shared Neighborhood Hits	130
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

CFC1_HUMAN
NC score	0.265452 (rank : 241)	θ value	0.365318 (rank : 315)
Query Neighborhood Hits	525	Target Neighborhood Hits	148	Shared Neighborhood Hits	139
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

FBLN5_HUMAN
NC score	0.264872 (rank : 242)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	525	Target Neighborhood Hits	329	Shared Neighborhood Hits	198
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
NC score	0.262917 (rank : 243)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	525	Target Neighborhood Hits	317	Shared Neighborhood Hits	190
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

KRA98_HUMAN
NC score	0.260180 (rank : 244)	θ value	0.0193708 (rank : 204)
Query Neighborhood Hits	525	Target Neighborhood Hits	185	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

FBLN4_HUMAN
NC score	0.256335 (rank : 245)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	525	Target Neighborhood Hits	278	Shared Neighborhood Hits	177
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

CELR2_HUMAN
NC score	0.256209 (rank : 246)	θ value	0.00509761 (rank : 170)
Query Neighborhood Hits	525	Target Neighborhood Hits	657	Shared Neighborhood Hits	265
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

MATN2_HUMAN
NC score	0.256115 (rank : 247)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	525	Target Neighborhood Hits	365	Shared Neighborhood Hits	186
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

CELR3_HUMAN
NC score	0.252238 (rank : 248)	θ value	0.365318 (rank : 314)
Query Neighborhood Hits	525	Target Neighborhood Hits	680	Shared Neighborhood Hits	267
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

DMBT1_MOUSE
NC score	0.250899 (rank : 249)	θ value	4.1701e-05 (rank : 106)
Query Neighborhood Hits	525	Target Neighborhood Hits	134	Shared Neighborhood Hits	54
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

FBLN3_HUMAN
NC score	0.250211 (rank : 250)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	525	Target Neighborhood Hits	293	Shared Neighborhood Hits	178
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

CELR3_MOUSE
NC score	0.250209 (rank : 251)	θ value	0.0431538 (rank : 228)
Query Neighborhood Hits	525	Target Neighborhood Hits	687	Shared Neighborhood Hits	272
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

FBLN4_MOUSE
NC score	0.249961 (rank : 252)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	525	Target Neighborhood Hits	270	Shared Neighborhood Hits	172
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

HCFC2_HUMAN
NC score	0.248979 (rank : 253)	θ value	7.59969e-07 (rank : 70)
Query Neighborhood Hits	525	Target Neighborhood Hits	154	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

EGF_HUMAN
NC score	0.248799 (rank : 254)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	525	Target Neighborhood Hits	343	Shared Neighborhood Hits	213
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

CELR1_MOUSE
NC score	0.248758 (rank : 255)	θ value	0.000786445 (rank : 137)
Query Neighborhood Hits	525	Target Neighborhood Hits	617	Shared Neighborhood Hits	258
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

MATN2_MOUSE
NC score	0.248495 (rank : 256)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	525	Target Neighborhood Hits	356	Shared Neighborhood Hits	182
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

VLDLR_HUMAN
NC score	0.248479 (rank : 257)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	525	Target Neighborhood Hits	383	Shared Neighborhood Hits	210
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

SSPO_MOUSE
NC score	0.248121 (rank : 258)	θ value	0.0736092 (rank : 256)
Query Neighborhood Hits	525	Target Neighborhood Hits	800	Shared Neighborhood Hits	282
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

KR102_HUMAN
NC score	0.246996 (rank : 259)	θ value	8.99809 (rank : 514)
Query Neighborhood Hits	525	Target Neighborhood Hits	264	Shared Neighborhood Hits	143
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KRA11_HUMAN
NC score	0.246419 (rank : 260)	θ value	0.365318 (rank : 320)
Query Neighborhood Hits	525	Target Neighborhood Hits	155	Shared Neighborhood Hits	100
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

VLDLR_MOUSE
NC score	0.246149 (rank : 261)	θ value	6.88961 (rank : 504)
Query Neighborhood Hits	525	Target Neighborhood Hits	360	Shared Neighborhood Hits	200
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

CELR1_HUMAN
NC score	0.243741 (rank : 262)	θ value	0.0330416 (rank : 216)
Query Neighborhood Hits	525	Target Neighborhood Hits	613	Shared Neighborhood Hits	249
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CFC1_MOUSE
NC score	0.243726 (rank : 263)	θ value	0.279714 (rank : 304)
Query Neighborhood Hits	525	Target Neighborhood Hits	125	Shared Neighborhood Hits	119
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

LDLR_HUMAN
NC score	0.243359 (rank : 264)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	525	Target Neighborhood Hits	375	Shared Neighborhood Hits	219
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

PROZ_MOUSE
NC score	0.242515 (rank : 265)	θ value	4.03905 (rank : 460)
Query Neighborhood Hits	525	Target Neighborhood Hits	410	Shared Neighborhood Hits	195
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

KRA94_HUMAN
NC score	0.240772 (rank : 266)	θ value	6.88961 (rank : 492)
Query Neighborhood Hits	525	Target Neighborhood Hits	204	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

CELR2_MOUSE
NC score	0.240364 (rank : 267)	θ value	0.000786445 (rank : 138)
Query Neighborhood Hits	525	Target Neighborhood Hits	584	Shared Neighborhood Hits	236
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

TDGF1_MOUSE
NC score	0.239532 (rank : 268)	θ value	1.81305 (rank : 410)
Query Neighborhood Hits	525	Target Neighborhood Hits	146	Shared Neighborhood Hits	134
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

FBX42_MOUSE
NC score	0.238586 (rank : 269)	θ value	7.1131e-05 (rank : 114)
Query Neighborhood Hits	525	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PDJ6, Q8CE76, Q99KY2	Gene names	Fbxo42
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

LRP8_MOUSE
NC score	0.238571 (rank : 270)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	525	Target Neighborhood Hits	385	Shared Neighborhood Hits	200
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

KR105_HUMAN
NC score	0.236492 (rank : 271)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	525	Target Neighborhood Hits	271	Shared Neighborhood Hits	153
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KRA47_HUMAN
NC score	0.235993 (rank : 272)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	525	Target Neighborhood Hits	204	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KR10B_HUMAN
NC score	0.235136 (rank : 273)	θ value	1.81305 (rank : 401)
Query Neighborhood Hits	525	Target Neighborhood Hits	269	Shared Neighborhood Hits	140
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LDLR_MOUSE
NC score	0.234698 (rank : 274)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	525	Target Neighborhood Hits	382	Shared Neighborhood Hits	214
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

FBX42_HUMAN
NC score	0.234692 (rank : 275)	θ value	3.19293e-05 (rank : 103)
Query Neighborhood Hits	525	Target Neighborhood Hits	121	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

PROZ_HUMAN
NC score	0.234675 (rank : 276)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	525	Target Neighborhood Hits	422	Shared Neighborhood Hits	200
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

EMR1_HUMAN
NC score	0.234595 (rank : 277)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	525	Target Neighborhood Hits	382	Shared Neighborhood Hits	197
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

FBLN3_MOUSE
NC score	0.233549 (rank : 278)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	525	Target Neighborhood Hits	279	Shared Neighborhood Hits	166
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

KRA92_HUMAN
NC score	0.232645 (rank : 279)	θ value	1.06291 (rank : 372)
Query Neighborhood Hits	525	Target Neighborhood Hits	198	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA45_HUMAN
NC score	0.231985 (rank : 280)	θ value	0.47712 (rank : 330)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

SEZ6L_HUMAN
NC score	0.230055 (rank : 281)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	525	Target Neighborhood Hits	289	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

KR10C_HUMAN
NC score	0.228031 (rank : 282)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	525	Target Neighborhood Hits	219	Shared Neighborhood Hits	122
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

FATH_HUMAN
NC score	0.227942 (rank : 283)	θ value	0.0431538 (rank : 229)
Query Neighborhood Hits	525	Target Neighborhood Hits	570	Shared Neighborhood Hits	252
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

EMR2_HUMAN
NC score	0.226910 (rank : 284)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	525	Target Neighborhood Hits	345	Shared Neighborhood Hits	185
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

KRA13_HUMAN
NC score	0.226904 (rank : 285)	θ value	8.99809 (rank : 515)
Query Neighborhood Hits	525	Target Neighborhood Hits	144	Shared Neighborhood Hits	92
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

CD97_HUMAN
NC score	0.226608 (rank : 286)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	525	Target Neighborhood Hits	353	Shared Neighborhood Hits	188
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

LRP4_MOUSE
NC score	0.226224 (rank : 287)	θ value	3.0926 (rank : 434)
Query Neighborhood Hits	525	Target Neighborhood Hits	351	Shared Neighborhood Hits	193
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP4_HUMAN
NC score	0.225147 (rank : 288)	θ value	6.88961 (rank : 493)
Query Neighborhood Hits	525	Target Neighborhood Hits	355	Shared Neighborhood Hits	192
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

KREM2_HUMAN
NC score	0.224930 (rank : 289)	θ value	0.0330416 (rank : 224)
Query Neighborhood Hits	525	Target Neighborhood Hits	93	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KR109_HUMAN
NC score	0.224705 (rank : 290)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	525	Target Neighborhood Hits	226	Shared Neighborhood Hits	134
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR108_HUMAN
NC score	0.222983 (rank : 291)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	525	Target Neighborhood Hits	226	Shared Neighborhood Hits	124
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

PDGFD_HUMAN
NC score	0.221545 (rank : 292)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	525	Target Neighborhood Hits	74	Shared Neighborhood Hits	47
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

LRP8_HUMAN
NC score	0.221320 (rank : 293)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	525	Target Neighborhood Hits	346	Shared Neighborhood Hits	184
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

HCFC1_HUMAN
NC score	0.221257 (rank : 294)	θ value	2.21117e-06 (rank : 80)
Query Neighborhood Hits	525	Target Neighborhood Hits	331	Shared Neighborhood Hits	61
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

PDGFD_MOUSE
NC score	0.219198 (rank : 295)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	525	Target Neighborhood Hits	72	Shared Neighborhood Hits	46
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

DMBT1_HUMAN
NC score	0.219077 (rank : 296)	θ value	0.00020696 (rank : 124)
Query Neighborhood Hits	525	Target Neighborhood Hits	152	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

GRN_HUMAN
NC score	0.218865 (rank : 297)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	525	Target Neighborhood Hits	268	Shared Neighborhood Hits	148
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KRA44_HUMAN
NC score	0.218393 (rank : 298)	θ value	2.36792 (rank : 417)
Query Neighborhood Hits	525	Target Neighborhood Hits	162	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

CLC4A_HUMAN
NC score	0.218341 (rank : 299)	θ value	7.59969e-07 (rank : 69)
Query Neighborhood Hits	525	Target Neighborhood Hits	114	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UMR7, Q8WXW9, Q9H2Z9, Q9NS33, Q9UI34	Gene names	CLEC4A, CLECSF6, DCIR, LLIR
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member A (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (C-type lectin DDB27).

CD248_MOUSE
NC score	0.218181 (rank : 300)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	525	Target Neighborhood Hits	578	Shared Neighborhood Hits	178
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

HCFC1_MOUSE
NC score	0.217642 (rank : 301)	θ value	6.43352e-06 (rank : 89)
Query Neighborhood Hits	525	Target Neighborhood Hits	348	Shared Neighborhood Hits	64
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

CD248_HUMAN
NC score	0.216706 (rank : 302)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	525	Target Neighborhood Hits	679	Shared Neighborhood Hits	190
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CLC4K_HUMAN
NC score	0.215619 (rank : 303)	θ value	3.41135e-07 (rank : 65)
Query Neighborhood Hits	525	Target Neighborhood Hits	172	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UJ71	Gene names	CD207, CLEC4K
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member K (Langerin) (CD207 antigen).

KLH14_HUMAN
NC score	0.214926 (rank : 304)	θ value	7.59969e-07 (rank : 71)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P2G3	Gene names	KLHL14, KIAA1384
Domain Architecture	No domain graphic available
Description	Kelch-like protein 14.

HABP2_HUMAN
NC score	0.214313 (rank : 305)	θ value	0.00390308 (rank : 165)
Query Neighborhood Hits	525	Target Neighborhood Hits	431	Shared Neighborhood Hits	215
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

SORL_MOUSE
NC score	0.212725 (rank : 306)	θ value	0.62314 (rank : 344)
Query Neighborhood Hits	525	Target Neighborhood Hits	439	Shared Neighborhood Hits	186
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TSP1_MOUSE
NC score	0.211679 (rank : 307)	θ value	0.21417 (rank : 302)
Query Neighborhood Hits	525	Target Neighborhood Hits	396	Shared Neighborhood Hits	186
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

KREM1_HUMAN
NC score	0.210716 (rank : 308)	θ value	0.0563607 (rank : 241)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

MT3_MOUSE
NC score	0.209996 (rank : 309)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	525	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

NRX1A_HUMAN
NC score	0.209967 (rank : 310)	θ value	1.38821 (rank : 391)
Query Neighborhood Hits	525	Target Neighborhood Hits	170	Shared Neighborhood Hits	117
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

ENC1_MOUSE
NC score	0.209171 (rank : 311)	θ value	8.40245e-06 (rank : 93)
Query Neighborhood Hits	525	Target Neighborhood Hits	190	Shared Neighborhood Hits	72
SwissProt Accessions	O35709	Gene names	Enc1, Enc-1
Domain Architecture
Description	Ectoderm-neural cortex 1 protein (ENC-1).

TSP1_HUMAN
NC score	0.208681 (rank : 312)	θ value	0.21417 (rank : 301)
Query Neighborhood Hits	525	Target Neighborhood Hits	389	Shared Neighborhood Hits	185
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

HABP2_MOUSE
NC score	0.208533 (rank : 313)	θ value	0.0330416 (rank : 219)
Query Neighborhood Hits	525	Target Neighborhood Hits	445	Shared Neighborhood Hits	221
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

PGCA_HUMAN
NC score	0.208503 (rank : 314)	θ value	0.0330416 (rank : 227)
Query Neighborhood Hits	525	Target Neighborhood Hits	821	Shared Neighborhood Hits	204
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

NRX1A_MOUSE
NC score	0.207992 (rank : 315)	θ value	1.81305 (rank : 408)
Query Neighborhood Hits	525	Target Neighborhood Hits	164	Shared Neighborhood Hits	116
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

KREM2_MOUSE
NC score	0.207289 (rank : 316)	θ value	0.0961366 (rank : 267)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

GRN_MOUSE
NC score	0.206361 (rank : 317)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	525	Target Neighborhood Hits	248	Shared Neighborhood Hits	139
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KBTBA_HUMAN
NC score	0.205969 (rank : 318)	θ value	8.97725e-08 (rank : 56)
Query Neighborhood Hits	525	Target Neighborhood Hits	184	Shared Neighborhood Hits	69
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

DCBD2_HUMAN
NC score	0.205577 (rank : 319)	θ value	1.06291 (rank : 365)
Query Neighborhood Hits	525	Target Neighborhood Hits	118	Shared Neighborhood Hits	57
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

ESM1_HUMAN
NC score	0.205556 (rank : 320)	θ value	1.81305 (rank : 399)
Query Neighborhood Hits	525	Target Neighborhood Hits	110	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

EMR1_MOUSE
NC score	0.205315 (rank : 321)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	525	Target Neighborhood Hits	349	Shared Neighborhood Hits	170
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

ENC1_HUMAN
NC score	0.205054 (rank : 322)	θ value	5.44631e-05 (rank : 107)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	72
SwissProt Accessions	O14682, O75464, Q9UPG9	Gene names	ENC1, NRPB, PIG10
Domain Architecture
Description	Ectoderm-neural cortex 1 protein (ENC-1) (p53-induced protein 10) (Nuclear matrix protein NRP/B).

KR414_HUMAN
NC score	0.204627 (rank : 323)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	525	Target Neighborhood Hits	199	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA99_HUMAN
NC score	0.203850 (rank : 324)	θ value	8.99809 (rank : 517)
Query Neighborhood Hits	525	Target Neighborhood Hits	173	Shared Neighborhood Hits	107
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

TDGF1_HUMAN
NC score	0.203540 (rank : 325)	θ value	0.62314 (rank : 345)
Query Neighborhood Hits	525	Target Neighborhood Hits	132	Shared Neighborhood Hits	121
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

MKLN1_HUMAN
NC score	0.203056 (rank : 326)	θ value	3.77169e-06 (rank : 84)
Query Neighborhood Hits	525	Target Neighborhood Hits	53	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UL63, Q9NSK4, Q9NUS8	Gene names	MKLN1
Domain Architecture
Description	Muskelin.

KLDC4_MOUSE
NC score	0.202512 (rank : 327)	θ value	0.00298849 (rank : 158)
Query Neighborhood Hits	525	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q921I2, Q8CIK0	Gene names	Klhdc4
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 4.

MKLN1_MOUSE
NC score	0.202105 (rank : 328)	θ value	3.77169e-06 (rank : 85)
Query Neighborhood Hits	525	Target Neighborhood Hits	54	Shared Neighborhood Hits	46
SwissProt Accessions	O89050	Gene names	Mkln1
Domain Architecture
Description	Muskelin.

SORL_HUMAN
NC score	0.201787 (rank : 329)	θ value	0.0961366 (rank : 271)
Query Neighborhood Hits	525	Target Neighborhood Hits	440	Shared Neighborhood Hits	180
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

MT3_HUMAN
NC score	0.200998 (rank : 330)	θ value	4.03905 (rank : 457)
Query Neighborhood Hits	525	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

KLH18_HUMAN
NC score	0.199338 (rank : 331)	θ value	0.0736092 (rank : 248)
Query Neighborhood Hits	525	Target Neighborhood Hits	143	Shared Neighborhood Hits	72
SwissProt Accessions	O94889, Q8N125	Gene names	KLHL18, KIAA0795
Domain Architecture
Description	Kelch-like protein 18.

CLC6A_MOUSE
NC score	0.199014 (rank : 332)	θ value	0.00134147 (rank : 146)
Query Neighborhood Hits	525	Target Neighborhood Hits	111	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JKF4, Q9JKF2, Q9JKF3	Gene names	Clec6a, Clecsf10, Dectin2
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated lectin 2) (DC-associated C-type lectin-2) (DECTIN-2).

LCE1C_HUMAN
NC score	0.198961 (rank : 333)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	525	Target Neighborhood Hits	65	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

KLH13_MOUSE
NC score	0.198868 (rank : 334)	θ value	0.00134147 (rank : 147)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	72
SwissProt Accessions	Q80TF4, Q9DBY7	Gene names	Klhl13, Bklhd2, Kiaa1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

NRX3A_HUMAN
NC score	0.198854 (rank : 335)	θ value	1.38821 (rank : 392)
Query Neighborhood Hits	525	Target Neighborhood Hits	164	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

LRP10_MOUSE
NC score	0.197990 (rank : 336)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	525	Target Neighborhood Hits	169	Shared Neighborhood Hits	94
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

DCBD2_MOUSE
NC score	0.197793 (rank : 337)	θ value	1.81305 (rank : 398)
Query Neighborhood Hits	525	Target Neighborhood Hits	113	Shared Neighborhood Hits	58
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

KLHL9_MOUSE
NC score	0.197225 (rank : 338)	θ value	0.00134147 (rank : 148)
Query Neighborhood Hits	525	Target Neighborhood Hits	195	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZPT1	Gene names	Klhl9, Kiaa1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

LRP10_HUMAN
NC score	0.196997 (rank : 339)	θ value	8.99809 (rank : 518)
Query Neighborhood Hits	525	Target Neighborhood Hits	197	Shared Neighborhood Hits	93
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

KEAP1_MOUSE
NC score	0.196586 (rank : 340)	θ value	1.43324e-05 (rank : 98)
Query Neighborhood Hits	525	Target Neighborhood Hits	182	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z2X8	Gene names	Keap1
Domain Architecture
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2).

KEAP1_HUMAN
NC score	0.196214 (rank : 341)	θ value	7.1131e-05 (rank : 115)
Query Neighborhood Hits	525	Target Neighborhood Hits	181	Shared Neighborhood Hits	68
SwissProt Accessions	Q14145, Q6LEP0	Gene names	KEAP1, KIAA0132, KLHL19
Domain Architecture	No domain graphic available
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (Kelch-like protein 19).

KLHL9_HUMAN
NC score	0.195560 (rank : 342)	θ value	0.00665767 (rank : 177)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P2J3, Q8TCQ2	Gene names	KLHL9, KIAA1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

CLC1A_HUMAN
NC score	0.195552 (rank : 343)	θ value	8.40245e-06 (rank : 92)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NC01, Q8IUW7, Q9NZH3	Gene names	CLEC1A, CLEC1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 1 member A (C-type lectin-like receptor 1) (CLEC-1).

KREM1_MOUSE
NC score	0.193801 (rank : 344)	θ value	0.62314 (rank : 339)
Query Neighborhood Hits	525	Target Neighborhood Hits	92	Shared Neighborhood Hits	60
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KLH13_HUMAN
NC score	0.192966 (rank : 345)	θ value	0.0193708 (rank : 203)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P2N7, Q6P2E3, Q96QI7, Q9UDN9	Gene names	KLHL13, BKLHD2, KIAA1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

MATN4_HUMAN
NC score	0.192523 (rank : 346)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	525	Target Neighborhood Hits	287	Shared Neighborhood Hits	157
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

KR412_HUMAN
NC score	0.192493 (rank : 347)	θ value	1.81305 (rank : 402)
Query Neighborhood Hits	525	Target Neighborhood Hits	178	Shared Neighborhood Hits	103
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

CLC4C_HUMAN
NC score	0.192487 (rank : 348)	θ value	0.00298849 (rank : 156)
Query Neighborhood Hits	525	Target Neighborhood Hits	111	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WTT0, Q3T1C3, Q6UXS8, Q8WXX8	Gene names	CLEC4C, BDCA2, CLECSF11, CLECSF7, DLEC, HECL
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member C (C-type lectin superfamily member 7) (Blood dendritic cell antigen 2 protein) (BDCA-2) (Dendritic lectin) (CD303 antigen).

KLDC1_HUMAN
NC score	0.192187 (rank : 349)	θ value	0.0736092 (rank : 247)
Query Neighborhood Hits	525	Target Neighborhood Hits	66	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N7A1, Q8WYI1	Gene names	KLHDC1
Domain Architecture
Description	Kelch domain-containing protein 1.

KLHL5_HUMAN
NC score	0.192012 (rank : 350)	θ value	6.43352e-06 (rank : 90)
Query Neighborhood Hits	525	Target Neighborhood Hits	188	Shared Neighborhood Hits	66
SwissProt Accessions	Q96PQ7, Q86XW0, Q9NUK3, Q9NV27, Q9NVA9, Q9Y2X2	Gene names	KLHL5
Domain Architecture
Description	Kelch-like protein 5.

KHL15_HUMAN
NC score	0.191973 (rank : 351)	θ value	0.00228821 (rank : 154)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	70
SwissProt Accessions	Q96M94, Q32MN3, Q8NDA3, Q96BM6, Q9C0I6	Gene names	KLHL15, KIAA1677
Domain Architecture	No domain graphic available
Description	Kelch-like protein 15.

KLHL1_MOUSE
NC score	0.191905 (rank : 352)	θ value	0.00035302 (rank : 128)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JI74	Gene names	Klhl1
Domain Architecture
Description	Kelch-like protein 1.

KLHL1_HUMAN
NC score	0.191493 (rank : 353)	θ value	0.000786445 (rank : 139)
Query Neighborhood Hits	525	Target Neighborhood Hits	195	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NR64, Q5VZ64, Q9H4X4, Q9NR65, Q9P238	Gene names	KLHL1, KIAA1490
Domain Architecture
Description	Kelch-like protein 1.

KLDC1_MOUSE
NC score	0.190840 (rank : 354)	θ value	0.47712 (rank : 329)
Query Neighborhood Hits	525	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	Q80YG3	Gene names	Klhdc1
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 1.

KLDC4_HUMAN
NC score	0.190246 (rank : 355)	θ value	0.62314 (rank : 335)
Query Neighborhood Hits	525	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TBB5, Q96F29, Q9BVN3	Gene names	KLHDC4
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 4.

KLDC5_HUMAN
NC score	0.190101 (rank : 356)	θ value	0.125558 (rank : 279)
Query Neighborhood Hits	525	Target Neighborhood Hits	83	Shared Neighborhood Hits	65
SwissProt Accessions	Q9P2K6, Q2VPK1, Q8N334	Gene names	KLHDC5, KIAA1340
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 5.

ST14_HUMAN
NC score	0.189576 (rank : 357)	θ value	4.92598e-06 (rank : 88)
Query Neighborhood Hits	525	Target Neighborhood Hits	409	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

CLC4A_MOUSE
NC score	0.189127 (rank : 358)	θ value	0.0961366 (rank : 259)
Query Neighborhood Hits	525	Target Neighborhood Hits	103	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QZ15, Q4VA33	Gene names	Clec4a, Clec4a2, Clecsf6, Dcir
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member A (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor).

CLC4E_MOUSE
NC score	0.188402 (rank : 359)	θ value	0.00298849 (rank : 157)
Query Neighborhood Hits	525	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R0Q8	Gene names	Clec4e, Clecsf9, Mincle
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).

LCE1B_HUMAN
NC score	0.187920 (rank : 360)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	525	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

MATN3_MOUSE
NC score	0.186611 (rank : 361)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	525	Target Neighborhood Hits	261	Shared Neighborhood Hits	146
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

GAN_HUMAN
NC score	0.186228 (rank : 362)	θ value	0.0113563 (rank : 189)
Query Neighborhood Hits	525	Target Neighborhood Hits	180	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H2C0	Gene names	GAN, GAN1, KLHL16
Domain Architecture
Description	Gigaxonin (Kelch-like protein 16).

ST14_MOUSE
NC score	0.186163 (rank : 363)	θ value	5.44631e-05 (rank : 111)
Query Neighborhood Hits	525	Target Neighborhood Hits	419	Shared Neighborhood Hits	175
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

CLC4K_MOUSE
NC score	0.186099 (rank : 364)	θ value	0.00665767 (rank : 174)
Query Neighborhood Hits	525	Target Neighborhood Hits	165	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VBX4, Q8R442	Gene names	Cd207, Clec4k
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member K (Langerin) (CD207 antigen).

CLC10_HUMAN
NC score	0.186012 (rank : 365)	θ value	0.00134147 (rank : 145)
Query Neighborhood Hits	525	Target Neighborhood Hits	134	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IUN9, Q14538, Q6PIW3	Gene names	CLEC10A, CLECSF14, HML
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD301 antigen).

KLH10_HUMAN
NC score	0.185747 (rank : 366)	θ value	0.0330416 (rank : 222)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	68
SwissProt Accessions	Q6JEL2, Q6NW28, Q96MC0	Gene names	KLHL10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

MATN3_HUMAN
NC score	0.185600 (rank : 367)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	525	Target Neighborhood Hits	268	Shared Neighborhood Hits	143
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

NRX2A_HUMAN
NC score	0.185599 (rank : 368)	θ value	2.36792 (rank : 422)
Query Neighborhood Hits	525	Target Neighborhood Hits	614	Shared Neighborhood Hits	128
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

TDGF2_HUMAN
NC score	0.185587 (rank : 369)	θ value	5.27518 (rank : 480)
Query Neighborhood Hits	525	Target Neighborhood Hits	131	Shared Neighborhood Hits	116
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

KLH23_HUMAN
NC score	0.185231 (rank : 370)	θ value	0.0736092 (rank : 249)
Query Neighborhood Hits	525	Target Neighborhood Hits	198	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NBE8, Q8N9B9, Q96FT8	Gene names	KLHL23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

KLH10_MOUSE
NC score	0.185047 (rank : 371)	θ value	0.0193708 (rank : 202)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D5V2, Q8BVM3, Q9DA07	Gene names	Klhl10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

NFX1_HUMAN
NC score	0.184934 (rank : 372)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	525	Target Neighborhood Hits	405	Shared Neighborhood Hits	138
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

CLC4D_HUMAN
NC score	0.184557 (rank : 373)	θ value	0.00390308 (rank : 163)
Query Neighborhood Hits	525	Target Neighborhood Hits	111	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WXI8, Q8N5J5	Gene names	CLEC4D, CLECSF8, MCL
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member D (C-type lectin superfamily member 8) (C-type lectin-like receptor 6) (CLEC-6).

KLDC5_MOUSE
NC score	0.184410 (rank : 374)	θ value	0.163984 (rank : 291)
Query Neighborhood Hits	525	Target Neighborhood Hits	86	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BFQ9, Q6ZPT4	Gene names	Klhdc5, Kiaa1340
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 5.

KR10A_HUMAN
NC score	0.184225 (rank : 375)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	525	Target Neighborhood Hits	232	Shared Neighborhood Hits	132
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KLH12_MOUSE
NC score	0.183483 (rank : 376)	θ value	0.00869519 (rank : 182)
Query Neighborhood Hits	525	Target Neighborhood Hits	190	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BZM0, Q8K225	Gene names	Klhl12, C3ip1
Domain Architecture	No domain graphic available
Description	Kelch-like protein 12 (CUL3-interacting protein 1).

TSP2_MOUSE
NC score	0.183430 (rank : 377)	θ value	5.27518 (rank : 482)
Query Neighborhood Hits	525	Target Neighborhood Hits	352	Shared Neighborhood Hits	179
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

KLH12_HUMAN
NC score	0.183280 (rank : 378)	θ value	0.0113563 (rank : 190)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	67
SwissProt Accessions	Q53G59, Q9HBX5	Gene names	KLHL12, C3IP1
Domain Architecture	No domain graphic available
Description	Kelch-like protein 12 (CUL3-interacting protein 1).

CLC6A_HUMAN
NC score	0.182402 (rank : 379)	θ value	0.0563607 (rank : 236)
Query Neighborhood Hits	525	Target Neighborhood Hits	119	Shared Neighborhood Hits	59
SwissProt Accessions	Q6EIG7	Gene names	CLEC6A, CLECSF10, DECTIN2
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated lectin 2) (DC-associated C-type lectin-2) (DECTIN-2).

ESM1_MOUSE
NC score	0.182179 (rank : 380)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	525	Target Neighborhood Hits	107	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

MATN4_MOUSE
NC score	0.181998 (rank : 381)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	525	Target Neighborhood Hits	277	Shared Neighborhood Hits	150
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

KLH23_MOUSE
NC score	0.181355 (rank : 382)	θ value	0.125558 (rank : 280)
Query Neighborhood Hits	525	Target Neighborhood Hits	188	Shared Neighborhood Hits	72
SwissProt Accessions	Q6GQU2, Q8C840	Gene names	Klhl23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

RELN_MOUSE
NC score	0.181067 (rank : 383)	θ value	0.813845 (rank : 358)
Query Neighborhood Hits	525	Target Neighborhood Hits	235	Shared Neighborhood Hits	164
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

OLR1_HUMAN
NC score	0.180816 (rank : 384)	θ value	0.000270298 (rank : 126)
Query Neighborhood Hits	525	Target Neighborhood Hits	152	Shared Neighborhood Hits	57
SwissProt Accessions	P78380, Q2PP00, Q7Z484	Gene names	OLR1, LOX1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) (hLOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

RELN_HUMAN
NC score	0.180717 (rank : 385)	θ value	0.365318 (rank : 324)
Query Neighborhood Hits	525	Target Neighborhood Hits	233	Shared Neighborhood Hits	160
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

CLC4E_HUMAN
NC score	0.180142 (rank : 386)	θ value	0.21417 (rank : 296)
Query Neighborhood Hits	525	Target Neighborhood Hits	104	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULY5	Gene names	CLEC4E, CLECSF9, MINCLE
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).

HMCN1_HUMAN
NC score	0.179480 (rank : 387)	θ value	0.813845 (rank : 350)
Query Neighborhood Hits	525	Target Neighborhood Hits	983	Shared Neighborhood Hits	224
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KLHL7_HUMAN
NC score	0.179437 (rank : 388)	θ value	0.00509761 (rank : 172)
Query Neighborhood Hits	525	Target Neighborhood Hits	176	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IXQ5, Q9BQF8	Gene names	KLHL7
Domain Architecture	No domain graphic available
Description	Kelch-like protein 7.

KLHL7_MOUSE
NC score	0.179397 (rank : 389)	θ value	0.00869519 (rank : 183)
Query Neighborhood Hits	525	Target Neighborhood Hits	179	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BUL5, Q9CZP4	Gene names	Klhl7
Domain Architecture	No domain graphic available
Description	Kelch-like protein 7.

PCSK5_HUMAN
NC score	0.179147 (rank : 390)	θ value	6.88961 (rank : 498)
Query Neighborhood Hits	525	Target Neighborhood Hits	291	Shared Neighborhood Hits	153
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

TSP2_HUMAN
NC score	0.178513 (rank : 391)	θ value	2.36792 (rank : 424)
Query Neighborhood Hits	525	Target Neighborhood Hits	359	Shared Neighborhood Hits	177
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

GP126_HUMAN
NC score	0.178456 (rank : 392)	θ value	0.163984 (rank : 290)
Query Neighborhood Hits	525	Target Neighborhood Hits	187	Shared Neighborhood Hits	58
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

CLC9A_HUMAN
NC score	0.177632 (rank : 393)	θ value	0.0113563 (rank : 186)
Query Neighborhood Hits	525	Target Neighborhood Hits	95	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UXN8	Gene names	CLEC9A
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 9 member A.

KLH26_HUMAN
NC score	0.177123 (rank : 394)	θ value	0.125558 (rank : 281)
Query Neighborhood Hits	525	Target Neighborhood Hits	188	Shared Neighborhood Hits	66
SwissProt Accessions	Q53HC5, Q8TAP0, Q9NUX3	Gene names	KLHL26
Domain Architecture	No domain graphic available
Description	Kelch-like protein 26.

KBTB9_HUMAN
NC score	0.177118 (rank : 395)	θ value	0.125558 (rank : 277)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	68
SwissProt Accessions	Q96CT2, Q8N388, Q96BF0, Q96PW7	Gene names	KBTBD9, KIAA1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

BKLH5_HUMAN
NC score	0.176506 (rank : 396)	θ value	0.0961366 (rank : 258)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	69
SwissProt Accessions	Q96NJ5, Q96PY7	Gene names	BKLHD5, KIAA1900
Domain Architecture
Description	BTB and kelch domain-containing protein 5.

KBTB9_MOUSE
NC score	0.176460 (rank : 397)	θ value	0.125558 (rank : 278)
Query Neighborhood Hits	525	Target Neighborhood Hits	197	Shared Neighborhood Hits	68
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

MRC1_MOUSE
NC score	0.176323 (rank : 398)	θ value	0.000121331 (rank : 120)
Query Neighborhood Hits	525	Target Neighborhood Hits	156	Shared Neighborhood Hits	63
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

KLH20_MOUSE
NC score	0.176197 (rank : 399)	θ value	0.0252991 (rank : 212)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VCK5, Q8BWA2	Gene names	Klhl20, Kleip
Domain Architecture	No domain graphic available
Description	Kelch-like protein 20 (Kelch-like ECT2-interacting protein).

KLH20_HUMAN
NC score	0.176174 (rank : 400)	θ value	0.0252991 (rank : 211)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y2M5, Q5TZF2, Q9H457	Gene names	KLHL20, KLEIP
Domain Architecture
Description	Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch- like protein X).

MUC5B_HUMAN
NC score	0.175839 (rank : 401)	θ value	3.0926 (rank : 437)
Query Neighborhood Hits	525	Target Neighborhood Hits	1020	Shared Neighborhood Hits	217
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MRC1_HUMAN
NC score	0.175577 (rank : 402)	θ value	5.44631e-05 (rank : 109)
Query Neighborhood Hits	525	Target Neighborhood Hits	157	Shared Neighborhood Hits	65
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

KLHL4_HUMAN
NC score	0.175225 (rank : 403)	θ value	4.03905 (rank : 452)
Query Neighborhood Hits	525	Target Neighborhood Hits	212	Shared Neighborhood Hits	69
SwissProt Accessions	Q9C0H6, Q9Y3J5	Gene names	KLHL4, KIAA1687
Domain Architecture
Description	Kelch-like protein 4.

C209A_MOUSE
NC score	0.174738 (rank : 404)	θ value	0.00228821 (rank : 152)
Query Neighborhood Hits	525	Target Neighborhood Hits	117	Shared Neighborhood Hits	59
SwissProt Accessions	Q91ZX1, Q3TAT9, Q91ZW5	Gene names	Cd209a, Cire
Domain Architecture
Description	CD209 antigen-like protein A (Dendritic cell-specific ICAM-3-grabbing nonintegrin) (DC-SIGN).

KR103_HUMAN
NC score	0.174573 (rank : 405)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	525	Target Neighborhood Hits	212	Shared Neighborhood Hits	116
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KLH22_HUMAN
NC score	0.174569 (rank : 406)	θ value	0.163984 (rank : 292)
Query Neighborhood Hits	525	Target Neighborhood Hits	198	Shared Neighborhood Hits	71
SwissProt Accessions	Q53GT1, Q96B68, Q96KC6	Gene names	KLHL22
Domain Architecture	No domain graphic available
Description	Kelch-like protein 22.

CNTP2_MOUSE
NC score	0.174452 (rank : 407)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	130
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

IPP_MOUSE
NC score	0.174046 (rank : 408)	θ value	0.365318 (rank : 317)
Query Neighborhood Hits	525	Target Neighborhood Hits	188	Shared Neighborhood Hits	65
SwissProt Accessions	P28575	Gene names	Ipp, Mipp
Domain Architecture
Description	Actin-binding protein IPP (MIPP protein) (Murine IAP-promoted placenta-expressed protein).

CNTP4_HUMAN
NC score	0.173915 (rank : 409)	θ value	3.0926 (rank : 430)
Query Neighborhood Hits	525	Target Neighborhood Hits	187	Shared Neighborhood Hits	116
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP2_HUMAN
NC score	0.173900 (rank : 410)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	525	Target Neighborhood Hits	199	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

ELTD1_MOUSE
NC score	0.173867 (rank : 411)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	525	Target Neighborhood Hits	288	Shared Neighborhood Hits	149
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

ZAN_HUMAN
NC score	0.173844 (rank : 412)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	525	Target Neighborhood Hits	679	Shared Neighborhood Hits	227
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

KBTB3_HUMAN
NC score	0.172813 (rank : 413)	θ value	0.0431538 (rank : 232)
Query Neighborhood Hits	525	Target Neighborhood Hits	176	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NAB2, Q86X38, Q96NK5	Gene names	KBTBD3, BKLHD3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

KBTB3_MOUSE
NC score	0.172774 (rank : 414)	θ value	0.0431538 (rank : 233)
Query Neighborhood Hits	525	Target Neighborhood Hits	176	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BHI4, Q8BNJ8	Gene names	Kbtbd3, Bklhd3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

CD97_MOUSE
NC score	0.172372 (rank : 415)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	525	Target Neighborhood Hits	295	Shared Neighborhood Hits	147
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CNTP4_MOUSE
NC score	0.172262 (rank : 416)	θ value	4.03905 (rank : 444)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	130
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

ASGR1_MOUSE
NC score	0.171936 (rank : 417)	θ value	0.00665767 (rank : 173)
Query Neighborhood Hits	525	Target Neighborhood Hits	135	Shared Neighborhood Hits	59
SwissProt Accessions	P34927, Q64363	Gene names	Asgr1, Asgr-1
Domain Architecture
Description	Asialoglycoprotein receptor 1 (ASGPR 1) (ASGP-R 1) (Hepatic lectin 1) (MHL-1).

BTBD5_HUMAN
NC score	0.171715 (rank : 418)	θ value	1.06291 (rank : 363)
Query Neighborhood Hits	525	Target Neighborhood Hits	190	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NXS3	Gene names	BTBD5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

ASGR2_MOUSE
NC score	0.171553 (rank : 419)	θ value	0.0961366 (rank : 257)
Query Neighborhood Hits	525	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	P24721	Gene names	Asgr2, Asgr-2
Domain Architecture
Description	Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin 2) (MHL-2).

MMGL_MOUSE
NC score	0.171183 (rank : 420)	θ value	0.00869519 (rank : 185)
Query Neighborhood Hits	525	Target Neighborhood Hits	270	Shared Neighborhood Hits	57
SwissProt Accessions	P49300	Gene names	Mgl1, Mgl
Domain Architecture
Description	Macrophage asialoglycoprotein-binding protein 1 (M-ASGP-BP) (Macrophage galactose/N-acetylgalactosamine-specific lectin) (MMGL).

DCBD1_MOUSE
NC score	0.171165 (rank : 421)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

REG4_MOUSE
NC score	0.171078 (rank : 422)	θ value	0.00390308 (rank : 169)
Query Neighborhood Hits	525	Target Neighborhood Hits	101	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D8G5, Q3TS25, Q9D858	Gene names	Reg4
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 4 precursor.

KLH17_MOUSE
NC score	0.170671 (rank : 423)	θ value	0.279714 (rank : 309)
Query Neighborhood Hits	525	Target Neighborhood Hits	200	Shared Neighborhood Hits	66
SwissProt Accessions	Q6TDP3	Gene names	Klhl17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

KLH26_MOUSE
NC score	0.170363 (rank : 424)	θ value	1.06291 (rank : 368)
Query Neighborhood Hits	525	Target Neighborhood Hits	190	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BGY4, Q8CIG6, Q8R153	Gene names	Klhl26
Domain Architecture	No domain graphic available
Description	Kelch-like protein 26.

C209E_MOUSE
NC score	0.170293 (rank : 425)	θ value	0.0148317 (rank : 193)
Query Neighborhood Hits	525	Target Neighborhood Hits	117	Shared Neighborhood Hits	57
SwissProt Accessions	Q91ZW7	Gene names	Cd209e
Domain Architecture
Description	CD209 antigen-like protein E (DC-SIGN-related protein 4) (DC-SIGNR4).

CLC1A_MOUSE
NC score	0.169922 (rank : 426)	θ value	7.1131e-05 (rank : 113)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BWY2, Q7TPX7, Q8BMH5	Gene names	Clec1a
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 1 member A.

BTBD5_MOUSE
NC score	0.169846 (rank : 427)	θ value	1.38821 (rank : 380)
Query Neighborhood Hits	525	Target Neighborhood Hits	189	Shared Neighborhood Hits	67
SwissProt Accessions	Q9CR40, Q9CYV0	Gene names	Btbd5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

KLHL3_HUMAN
NC score	0.169821 (rank : 428)	θ value	1.06291 (rank : 369)
Query Neighborhood Hits	525	Target Neighborhood Hits	187	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UH77, Q9UH75, Q9UH76, Q9ULU0, Q9Y6V6	Gene names	KLHL3, KIAA1129
Domain Architecture
Description	Kelch-like protein 3.

KLH22_MOUSE
NC score	0.169745 (rank : 429)	θ value	0.62314 (rank : 336)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	67
SwissProt Accessions	Q99JN2, Q8BT13	Gene names	Klhl22, Kelchl
Domain Architecture	No domain graphic available
Description	Kelch-like protein 22.

ASGR1_HUMAN
NC score	0.169551 (rank : 430)	θ value	0.0252991 (rank : 206)
Query Neighborhood Hits	525	Target Neighborhood Hits	137	Shared Neighborhood Hits	60
SwissProt Accessions	P07306	Gene names	ASGR1
Domain Architecture
Description	Asialoglycoprotein receptor 1 (ASGPR 1) (ASGP-R 1) (Hepatic lectin H1).

KLHL6_MOUSE
NC score	0.169416 (rank : 431)	θ value	0.813845 (rank : 351)
Query Neighborhood Hits	525	Target Neighborhood Hits	186	Shared Neighborhood Hits	63
SwissProt Accessions	Q6V595	Gene names	Klhl6
Domain Architecture	No domain graphic available
Description	Kelch-like protein 6.

KLD8A_HUMAN
NC score	0.169369 (rank : 432)	θ value	5.27518 (rank : 473)
Query Neighborhood Hits	525	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IYD2, Q9NVG5	Gene names	KLHDC8A
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8A.

KRA15_HUMAN
NC score	0.168733 (rank : 433)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	525	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KLD8A_MOUSE
NC score	0.168426 (rank : 434)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	525	Target Neighborhood Hits	85	Shared Neighborhood Hits	71
SwissProt Accessions	Q91XA8	Gene names	Klhdc8a
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8A.

KLH17_HUMAN
NC score	0.168258 (rank : 435)	θ value	0.365318 (rank : 319)
Query Neighborhood Hits	525	Target Neighborhood Hits	201	Shared Neighborhood Hits	66
SwissProt Accessions	Q6TDP4	Gene names	KLHL17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

CLC4D_MOUSE
NC score	0.168118 (rank : 436)	θ value	0.813845 (rank : 347)
Query Neighborhood Hits	525	Target Neighborhood Hits	104	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z2H6, Q8C212	Gene names	Clec4d, Clecsf8, Mcl
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member D (C-type lectin superfamily member 8) (Macrophage-restricted C-type lectin).

KLHL2_HUMAN
NC score	0.167587 (rank : 437)	θ value	1.38821 (rank : 386)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	65
SwissProt Accessions	O95198, Q8N484, Q8TBH5	Gene names	KLHL2
Domain Architecture
Description	Kelch-like protein 2 (Actin-binding protein Mayven).

KLHL2_MOUSE
NC score	0.167556 (rank : 438)	θ value	1.38821 (rank : 387)
Query Neighborhood Hits	525	Target Neighborhood Hits	190	Shared Neighborhood Hits	65
SwissProt Accessions	Q8JZP3, Q8CCU0, Q8R3U4	Gene names	Klhl2
Domain Architecture	No domain graphic available
Description	Kelch-like protein 2.

MRC2_HUMAN
NC score	0.167184 (rank : 439)	θ value	0.00665767 (rank : 178)
Query Neighborhood Hits	525	Target Neighborhood Hits	162	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UBG0, Q7LGE7, Q9Y5P9	Gene names	MRC2, ENDO180, KIAA0709, UPARAP
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Urokinase receptor-associated protein) (Endocytic receptor 180) (CD280 antigen).

IPP_HUMAN
NC score	0.166769 (rank : 440)	θ value	0.279714 (rank : 308)
Query Neighborhood Hits	525	Target Neighborhood Hits	186	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y573	Gene names	IPP
Domain Architecture
Description	Actin-binding protein IPP (MIPP protein).

KLHL8_HUMAN
NC score	0.165857 (rank : 441)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	525	Target Neighborhood Hits	180	Shared Neighborhood Hits	65
SwissProt Accessions	Q9P2G9	Gene names	KLHL8, KIAA1378
Domain Architecture
Description	Kelch-like protein 8.

HGFA_HUMAN
NC score	0.165822 (rank : 442)	θ value	0.21417 (rank : 298)
Query Neighborhood Hits	525	Target Neighborhood Hits	436	Shared Neighborhood Hits	207
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

CD69_HUMAN
NC score	0.165814 (rank : 443)	θ value	0.0193708 (rank : 199)
Query Neighborhood Hits	525	Target Neighborhood Hits	99	Shared Neighborhood Hits	52
SwissProt Accessions	Q07108	Gene names	CD69
Domain Architecture
Description	Early activation antigen CD69 (Early T-cell activation antigen p60) (GP32/28) (Leu-23) (MLR-3) (EA1) (BL-AC/P26) (Activation inducer molecule) (AIM).

KLHL6_HUMAN
NC score	0.165099 (rank : 444)	θ value	1.81305 (rank : 400)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WZ60, Q8N5I1, Q8N892	Gene names	KLHL6
Domain Architecture
Description	Kelch-like protein 6.

MRC2_MOUSE
NC score	0.165029 (rank : 445)	θ value	0.0193708 (rank : 205)
Query Neighborhood Hits	525	Target Neighborhood Hits	159	Shared Neighborhood Hits	62
SwissProt Accessions	Q64449, Q6ZQ64, Q8C6P0	Gene names	Mrc2, Kiaa0709
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 2 precursor (Lectin lambda) (CD280 antigen).

CLC9A_MOUSE
NC score	0.164896 (rank : 446)	θ value	0.21417 (rank : 297)
Query Neighborhood Hits	525	Target Neighborhood Hits	97	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BRU4	Gene names	Clec9a
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 9 member A.

KLHL8_MOUSE
NC score	0.164783 (rank : 447)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	63
SwissProt Accessions	P59280	Gene names	Klhl8
Domain Architecture
Description	Kelch-like protein 8.

CALI_HUMAN
NC score	0.164386 (rank : 448)	θ value	0.62314 (rank : 333)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	64
SwissProt Accessions	Q13939, Q9BXG7	Gene names	CCIN
Domain Architecture
Description	Calicin.

MEP1A_MOUSE
NC score	0.163854 (rank : 449)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	525	Target Neighborhood Hits	166	Shared Neighborhood Hits	109
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MT1X_HUMAN
NC score	0.163829 (rank : 450)	θ value	1.81305 (rank : 406)
Query Neighborhood Hits	525	Target Neighborhood Hits	76	Shared Neighborhood Hits	51
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

C1RA_MOUSE
NC score	0.163325 (rank : 451)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	525	Target Neighborhood Hits	379	Shared Neighborhood Hits	140
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

KLD8B_MOUSE
NC score	0.163053 (rank : 452)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	525	Target Neighborhood Hits	80	Shared Neighborhood Hits	66
SwissProt Accessions	Q9D2D9	Gene names	Klhdc8b
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

MASP1_HUMAN
NC score	0.163015 (rank : 453)	θ value	2.36792 (rank : 420)
Query Neighborhood Hits	525	Target Neighborhood Hits	369	Shared Neighborhood Hits	125
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

DCBD1_HUMAN
NC score	0.161453 (rank : 454)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	525	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

C1RB_MOUSE
NC score	0.161379 (rank : 455)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	525	Target Neighborhood Hits	380	Shared Neighborhood Hits	140
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

TIE1_HUMAN
NC score	0.161362 (rank : 456)	θ value	0.00298849 (rank : 162)
Query Neighborhood Hits	525	Target Neighborhood Hits	1241	Shared Neighborhood Hits	241
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

C209D_MOUSE
NC score	0.161028 (rank : 457)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	58
SwissProt Accessions	Q91ZW8, Q8VIK4	Gene names	Cd209d
Domain Architecture
Description	CD209 antigen-like protein D (DC-SIGN-related protein 3) (DC-SIGNR3).

HGFA_MOUSE
NC score	0.160095 (rank : 458)	θ value	0.0563607 (rank : 238)
Query Neighborhood Hits	525	Target Neighborhood Hits	419	Shared Neighborhood Hits	201
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

MASP2_HUMAN
NC score	0.159996 (rank : 459)	θ value	4.03905 (rank : 455)
Query Neighborhood Hits	525	Target Neighborhood Hits	364	Shared Neighborhood Hits	125
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

KBTBB_MOUSE
NC score	0.159922 (rank : 460)	θ value	1.06291 (rank : 367)
Query Neighborhood Hits	525	Target Neighborhood Hits	184	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BNW9	Gene names	Kbtbd11, Kiaa0711
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 11.

MEP1A_HUMAN
NC score	0.159676 (rank : 461)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	525	Target Neighborhood Hits	162	Shared Neighborhood Hits	105
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

C209B_MOUSE
NC score	0.159626 (rank : 462)	θ value	0.163984 (rank : 287)
Query Neighborhood Hits	525	Target Neighborhood Hits	140	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CJ91, Q8BGZ0, Q8BHK7, Q8CJ86, Q8CJ87, Q8CJ88, Q8CJ89, Q8CJ90, Q8CJ92, Q8CJ93, Q8CJ94, Q91ZW4, Q91ZX0, Q9D8V4	Gene names	Cd209b
Domain Architecture
Description	CD209 antigen-like protein B (DC-SIGN-related protein 1) (DC-SIGNR1) (OtB7).

MASP2_MOUSE
NC score	0.159252 (rank : 463)	θ value	8.99809 (rank : 519)
Query Neighborhood Hits	525	Target Neighborhood Hits	382	Shared Neighborhood Hits	133
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

C1R_HUMAN
NC score	0.158694 (rank : 464)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	525	Target Neighborhood Hits	364	Shared Neighborhood Hits	128
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

ASGR2_HUMAN
NC score	0.158371 (rank : 465)	θ value	0.47712 (rank : 327)
Query Neighborhood Hits	525	Target Neighborhood Hits	121	Shared Neighborhood Hits	58
SwissProt Accessions	P07307, O00448, Q03969	Gene names	ASGR2
Domain Architecture
Description	Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin H2).

TIE1_MOUSE
NC score	0.158310 (rank : 466)	θ value	0.000270298 (rank : 127)
Query Neighborhood Hits	525	Target Neighborhood Hits	1266	Shared Neighborhood Hits	238
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TNR4_HUMAN
NC score	0.158181 (rank : 467)	θ value	1.81305 (rank : 412)
Query Neighborhood Hits	525	Target Neighborhood Hits	152	Shared Neighborhood Hits	62
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

KLD8B_HUMAN
NC score	0.157838 (rank : 468)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	525	Target Neighborhood Hits	80	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IXV7	Gene names	KLHDC8B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

LY75_HUMAN
NC score	0.157722 (rank : 469)	θ value	0.0736092 (rank : 250)
Query Neighborhood Hits	525	Target Neighborhood Hits	169	Shared Neighborhood Hits	66
SwissProt Accessions	O60449, O75913, Q7Z575, Q7Z577	Gene names	LY75, CD205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (gp200-MR6) (CD205 antigen).

LY75_MOUSE
NC score	0.156702 (rank : 470)	θ value	0.00134147 (rank : 149)
Query Neighborhood Hits	525	Target Neighborhood Hits	155	Shared Neighborhood Hits	64
SwissProt Accessions	Q60767, Q8C7T3, Q91XL8, Q9QUZ6	Gene names	Ly75, Cd205
Domain Architecture
Description	Lymphocyte antigen 75 precursor (DEC-205) (CD205 antigen).

FAT2_HUMAN
NC score	0.156700 (rank : 471)	θ value	4.03905 (rank : 448)
Query Neighborhood Hits	525	Target Neighborhood Hits	507	Shared Neighborhood Hits	206
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

MASP1_MOUSE
NC score	0.156540 (rank : 472)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	525	Target Neighborhood Hits	364	Shared Neighborhood Hits	125
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

KLDC2_HUMAN
NC score	0.155231 (rank : 473)	θ value	6.88961 (rank : 489)
Query Neighborhood Hits	525	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y2U9, Q6IAF0	Gene names	KLHDC2, HCA33
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 2 (Hepatocellular carcinoma-associated antigen 33) (Host cell factor homolog LCP).

TNR4_MOUSE
NC score	0.154736 (rank : 474)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	525	Target Neighborhood Hits	137	Shared Neighborhood Hits	63
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

CNTP3_HUMAN
NC score	0.154699 (rank : 475)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	525	Target Neighborhood Hits	195	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CT127_HUMAN
NC score	0.154464 (rank : 476)	θ value	1.06291 (rank : 364)
Query Neighborhood Hits	525	Target Neighborhood Hits	67	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

KBTBB_HUMAN
NC score	0.152874 (rank : 477)	θ value	5.27518 (rank : 472)
Query Neighborhood Hits	525	Target Neighborhood Hits	195	Shared Neighborhood Hits	65
SwissProt Accessions	O94819	Gene names	KBTBD11, KIAA0711, KLHDC7C
Domain Architecture	No domain graphic available
Description	Kelch repeat and BTB domain-containing protein 11 (Kelch domain- containing protein 7B).

KLD7B_HUMAN
NC score	0.152735 (rank : 478)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	525	Target Neighborhood Hits	94	Shared Neighborhood Hits	61
SwissProt Accessions	Q96G42	Gene names	KLHDC7B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 7B.

KBTB2_HUMAN
NC score	0.152531 (rank : 479)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	525	Target Neighborhood Hits	179	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IY47, Q86Y62, Q9P239, Q9UFM7	Gene names	KBTBD2, BKLHD1, KIAA1489
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 2 (BTB and kelch domain-containing protein 1).

CLC4F_MOUSE
NC score	0.152468 (rank : 480)	θ value	0.0961366 (rank : 260)
Query Neighborhood Hits	525	Target Neighborhood Hits	572	Shared Neighborhood Hits	72
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

KBTB7_HUMAN
NC score	0.152252 (rank : 481)	θ value	1.38821 (rank : 385)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WVZ9, Q8NB99, Q9H0I6	Gene names	KBTBD7
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 7.

KLH21_HUMAN
NC score	0.152091 (rank : 482)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	525	Target Neighborhood Hits	173	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UJP4, O75057	Gene names	KLHL21, KIAA0469
Domain Architecture
Description	Kelch-like protein 21.

PROC_MOUSE
NC score	0.151654 (rank : 483)	θ value	0.0563607 (rank : 243)
Query Neighborhood Hits	525	Target Neighborhood Hits	426	Shared Neighborhood Hits	198
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

KBTB6_HUMAN
NC score	0.151635 (rank : 484)	θ value	1.38821 (rank : 384)
Query Neighborhood Hits	525	Target Neighborhood Hits	175	Shared Neighborhood Hits	59
SwissProt Accessions	Q86V97, Q8N8L0, Q8NDM5, Q96MP6	Gene names	KBTBD6
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 6.

MEP1B_MOUSE
NC score	0.151538 (rank : 485)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	525	Target Neighborhood Hits	127	Shared Neighborhood Hits	85
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

KR410_HUMAN
NC score	0.151417 (rank : 486)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	525	Target Neighborhood Hits	156	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

FA12_HUMAN
NC score	0.150010 (rank : 487)	θ value	2.36792 (rank : 415)
Query Neighborhood Hits	525	Target Neighborhood Hits	425	Shared Neighborhood Hits	198
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FCER2_MOUSE
NC score	0.149703 (rank : 488)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	525	Target Neighborhood Hits	392	Shared Neighborhood Hits	62
SwissProt Accessions	P20693, Q61556, Q61557	Gene names	Fcer2, Fcer2a
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IGE receptor) (Fc-epsilon-RII) (CD23 antigen).

LCE1F_HUMAN
NC score	0.149086 (rank : 489)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	525	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

TEFF2_MOUSE
NC score	0.148806 (rank : 490)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	525	Target Neighborhood Hits	214	Shared Neighborhood Hits	120
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

C1S_HUMAN
NC score	0.148280 (rank : 491)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	525	Target Neighborhood Hits	359	Shared Neighborhood Hits	131
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

PCSK6_HUMAN
NC score	0.148188 (rank : 492)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	525	Target Neighborhood Hits	298	Shared Neighborhood Hits	134
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

CS1B_MOUSE
NC score	0.147718 (rank : 493)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	525	Target Neighborhood Hits	361	Shared Neighborhood Hits	124
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MUC13_MOUSE
NC score	0.147604 (rank : 494)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	525	Target Neighborhood Hits	447	Shared Neighborhood Hits	137
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MT1A_HUMAN
NC score	0.147457 (rank : 495)	θ value	4.03905 (rank : 456)
Query Neighborhood Hits	525	Target Neighborhood Hits	74	Shared Neighborhood Hits	53
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

CS1A_MOUSE
NC score	0.147413 (rank : 496)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	525	Target Neighborhood Hits	360	Shared Neighborhood Hits	123
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

TEFF2_HUMAN
NC score	0.147308 (rank : 497)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	525	Target Neighborhood Hits	211	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

CO6_HUMAN
NC score	0.146976 (rank : 498)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	525	Target Neighborhood Hits	331	Shared Neighborhood Hits	152
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

KLH11_MOUSE
NC score	0.146963 (rank : 499)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	525	Target Neighborhood Hits	177	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CE33, Q3TDZ6, Q91VP6	Gene names	Klhl11
Domain Architecture	No domain graphic available
Description	Kelch-like protein 11 precursor.

MT1H_HUMAN
NC score	0.146562 (rank : 500)	θ value	0.62314 (rank : 341)
Query Neighborhood Hits	525	Target Neighborhood Hits	78	Shared Neighborhood Hits	50
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

KLH11_HUMAN
NC score	0.146466 (rank : 501)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NVR0	Gene names	KLHL11
Domain Architecture	No domain graphic available
Description	Kelch-like protein 11 precursor.

KLDC2_MOUSE
NC score	0.146217 (rank : 502)	θ value	5.27518 (rank : 474)
Query Neighborhood Hits	525	Target Neighborhood Hits	44	Shared Neighborhood Hits	40
SwissProt Accessions	Q4G5Y1, Q99JY2, Q9D784	Gene names	Klhdc2
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 2 (Endothelial differentiation inhibitory protein TNG).

REG4_HUMAN
NC score	0.146047 (rank : 503)	θ value	3.0926 (rank : 440)
Query Neighborhood Hits	525	Target Neighborhood Hits	105	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYZ8, Q8NER6, Q8NER7	Gene names	REG4, GISP, RELP
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 4 precursor (Reg IV) (REG-like protein) (Gastrointestinal secretory protein).

IDD_HUMAN
NC score	0.145953 (rank : 504)	θ value	0.0330416 (rank : 220)
Query Neighborhood Hits	525	Target Neighborhood Hits	127	Shared Neighborhood Hits	62
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

MFGM_HUMAN
NC score	0.145361 (rank : 505)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	525	Target Neighborhood Hits	150	Shared Neighborhood Hits	110
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

VWF_HUMAN
NC score	0.144913 (rank : 506)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	525	Target Neighborhood Hits	396	Shared Neighborhood Hits	168
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

NKG2D_MOUSE
NC score	0.144627 (rank : 507)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	55
SwissProt Accessions	O54709	Gene names	Klrk1, Nkg2d
Domain Architecture
Description	NKG2-D type II integral membrane protein (NKG2-D-activating NK receptor) (NK cell receptor D) (Killer cell lectin-like receptor subfamily K member 1) (CD314 antigen).

CNTP1_HUMAN
NC score	0.143872 (rank : 508)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	525	Target Neighborhood Hits	196	Shared Neighborhood Hits	110
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

TIE2_HUMAN
NC score	0.143784 (rank : 509)	θ value	0.00102713 (rank : 143)
Query Neighborhood Hits	525	Target Neighborhood Hits	1192	Shared Neighborhood Hits	231
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

LCE1A_HUMAN
NC score	0.143258 (rank : 510)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	525	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

KRA42_HUMAN
NC score	0.143121 (rank : 511)	θ value	6.88961 (rank : 491)
Query Neighborhood Hits	525	Target Neighborhood Hits	149	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

IDD_MOUSE
NC score	0.142946 (rank : 512)	θ value	0.0431538 (rank : 230)
Query Neighborhood Hits	525	Target Neighborhood Hits	151	Shared Neighborhood Hits	61
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

C209C_MOUSE
NC score	0.142617 (rank : 513)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	525	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	Q91ZW9	Gene names	Cd209c
Domain Architecture
Description	CD209 antigen-like protein C (DC-SIGN-related protein 2) (DC-SIGNR2).

CNTP1_MOUSE
NC score	0.142505 (rank : 514)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	105
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

NKG2D_HUMAN
NC score	0.142305 (rank : 515)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	525	Target Neighborhood Hits	98	Shared Neighborhood Hits	53
SwissProt Accessions	P26718, Q9NR41	Gene names	KLRK1, NKG2D
Domain Architecture
Description	NKG2-D type II integral membrane protein (NKG2-D-activating NK receptor) (NK cell receptor D) (Killer cell lectin-like receptor subfamily K member 1) (CD314 antigen).

LCE1E_HUMAN
NC score	0.142138 (rank : 516)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	525	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

PGCA_MOUSE
NC score	0.141553 (rank : 517)	θ value	0.62314 (rank : 343)
Query Neighborhood Hits	525	Target Neighborhood Hits	643	Shared Neighborhood Hits	79
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

LCE1D_HUMAN
NC score	0.141529 (rank : 518)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	525	Target Neighborhood Hits	44	Shared Neighborhood Hits	25
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

KBTB4_HUMAN
NC score	0.141119 (rank : 519)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	525	Target Neighborhood Hits	187	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NVX7, Q6IA85, Q9BUC3, Q9NV76	Gene names	KBTBD4, BKLHD4
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4).

KBTB4_MOUSE
NC score	0.141053 (rank : 520)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	525	Target Neighborhood Hits	182	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R179, Q9CQX1	Gene names	Kbtbd4, Bklhd4
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4).

TIE2_MOUSE
NC score	0.140909 (rank : 521)	θ value	0.00102713 (rank : 144)
Query Neighborhood Hits	525	Target Neighborhood Hits	1204	Shared Neighborhood Hits	232
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

FA10_HUMAN
NC score	0.140501 (rank : 522)	θ value	1.38821 (rank : 383)
Query Neighborhood Hits	525	Target Neighborhood Hits	431	Shared Neighborhood Hits	186
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
NC score	0.140124 (rank : 523)	θ value	4.03905 (rank : 447)
Query Neighborhood Hits	525	Target Neighborhood Hits	435	Shared Neighborhood Hits	194
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA9_HUMAN
NC score	0.140043 (rank : 524)	θ value	0.813845 (rank : 349)
Query Neighborhood Hits	525	Target Neighborhood Hits	421	Shared Neighborhood Hits	190
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

SMDF_HUMAN
NC score	0.140002 (rank : 525)	θ value	1.06291 (rank : 378)
Query Neighborhood Hits	525	Target Neighborhood Hits	117	Shared Neighborhood Hits	69
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

CLC4G_MOUSE
NC score	0.139980 (rank : 526)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	525	Target Neighborhood Hits	155	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BNX1, Q5I0T7, Q8R188	Gene names	Clec4g
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member G.

TNR16_HUMAN
NC score	0.139792 (rank : 527)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	86
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

MT4_MOUSE
NC score	0.139043 (rank : 528)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	68
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

ENTK_MOUSE
NC score	0.139018 (rank : 529)	θ value	0.000270298 (rank : 125)
Query Neighborhood Hits	525	Target Neighborhood Hits	338	Shared Neighborhood Hits	92
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

KLRF1_HUMAN
NC score	0.138803 (rank : 530)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NZS2, Q96PR2, Q96PR3, Q9NZS1	Gene names	KLRF1, ML
Domain Architecture
Description	Killer cell lectin-like receptor subfamily F member 1 (Lectin-like receptor F1) (Activating coreceptor NKp80).

TNR9_MOUSE
NC score	0.136166 (rank : 531)	θ value	0.62314 (rank : 346)
Query Neighborhood Hits	525	Target Neighborhood Hits	137	Shared Neighborhood Hits	69
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

CD69_MOUSE
NC score	0.135989 (rank : 532)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	525	Target Neighborhood Hits	92	Shared Neighborhood Hits	52
SwissProt Accessions	P37217	Gene names	Cd69
Domain Architecture	No domain graphic available
Description	Early activation antigen CD69.

KLRBB_MOUSE
NC score	0.135503 (rank : 533)	θ value	1.06291 (rank : 370)
Query Neighborhood Hits	525	Target Neighborhood Hits	105	Shared Neighborhood Hits	59
SwissProt Accessions	P27812	Gene names	Klrb1b, Ly55-b, Ly55b
Domain Architecture
Description	Natural killer cell surface protein P1-34 (NKR-P1 34).

FCER2_HUMAN
NC score	0.135457 (rank : 534)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	525	Target Neighborhood Hits	213	Shared Neighborhood Hits	56
SwissProt Accessions	P06734	Gene names	FCER2, IGEBF
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IgE receptor) (Fc-epsilon-RII) (BLAST-2) (Immunoglobulin E-binding factor) (CD23 antigen) [Contains: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form].

ELTD1_HUMAN
NC score	0.135348 (rank : 535)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	525	Target Neighborhood Hits	269	Shared Neighborhood Hits	134
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

TNR23_MOUSE
NC score	0.134613 (rank : 536)	θ value	1.38821 (rank : 397)
Query Neighborhood Hits	525	Target Neighborhood Hits	114	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

CLC4G_HUMAN
NC score	0.133635 (rank : 537)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	525	Target Neighborhood Hits	141	Shared Neighborhood Hits	55
SwissProt Accessions	Q6UXB4	Gene names	CLEC4G
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member G.

VWF_MOUSE
NC score	0.133213 (rank : 538)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	525	Target Neighborhood Hits	381	Shared Neighborhood Hits	163
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CD209_HUMAN
NC score	0.132226 (rank : 539)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	525	Target Neighborhood Hits	244	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NNX6, Q96QP7, Q96QP8, Q96QP9, Q96QQ0, Q96QQ1, Q96QQ2, Q96QQ3, Q96QQ4, Q96QQ5, Q96QQ6, Q96QQ7, Q96QQ8	Gene names	CD209, CLEC4L
Domain Architecture
Description	CD209 antigen (Dendritic cell-specific ICAM-3-grabbing nonintegrin 1) (DC-SIGN1) (DC-SIGN) (C-type lectin domain family 4 member L).

CLC4M_HUMAN
NC score	0.131834 (rank : 540)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	525	Target Neighborhood Hits	291	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H2X3, Q69F40, Q969M4, Q96QP3, Q96QP4, Q96QP5, Q96QP6, Q9BXS3, Q9H2Q9, Q9H8F0, Q9Y2A8	Gene names	CLEC4M, CD209L, CD209L1
Domain Architecture
Description	C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (Dendritic cell-specific ICAM-3-grabbing nonintegrin 2) (DC-SIGN2) (DC-SIGN-related protein) (DC-SIGNR) (Liver/lymph node-specific ICAM- 3-grabbing nonintegrin) (L-SIGN) (CD299 antigen).

MT1B_HUMAN
NC score	0.130946 (rank : 541)	θ value	3.0926 (rank : 436)
Query Neighborhood Hits	525	Target Neighborhood Hits	87	Shared Neighborhood Hits	55
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

PROC_HUMAN
NC score	0.129131 (rank : 542)	θ value	3.0926 (rank : 439)
Query Neighborhood Hits	525	Target Neighborhood Hits	406	Shared Neighborhood Hits	187
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

CLC5A_HUMAN
NC score	0.127686 (rank : 543)	θ value	1.38821 (rank : 381)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NY25, Q9UKQ0	Gene names	CLEC5A, CLECSF5, MDL1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 5 member A (C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin) (MDL-1).

FA7_HUMAN
NC score	0.126688 (rank : 544)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	525	Target Neighborhood Hits	404	Shared Neighborhood Hits	179
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

KLRD1_HUMAN
NC score	0.126454 (rank : 545)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	525	Target Neighborhood Hits	101	Shared Neighborhood Hits	55
SwissProt Accessions	Q13241, O43321, O43773, Q9UBE3, Q9UEQ0	Gene names	KLRD1, CD94
Domain Architecture
Description	Natural killer cells antigen CD94 (NK cell receptor) (Killer cell lectin-like receptor subfamily D member 1) (KP43).

CORIN_HUMAN
NC score	0.125944 (rank : 546)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	525	Target Neighborhood Hits	453	Shared Neighborhood Hits	174
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CLC2B_HUMAN
NC score	0.125768 (rank : 547)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	Q92478, Q8IZE9, Q9BS74, Q9UQB4	Gene names	CLEC2B, AICL, CLECSF2, IFNRG1
Domain Architecture
Description	C-type lectin domain family 2 member B (C-type lectin superfamily member 2) (Activation-induced C-type lectin) (IFN-alpha2b-inducing- related protein 1) (C-type lectin domain family 2 member B).

LCE4A_HUMAN
NC score	0.125016 (rank : 548)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	525	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

TNR16_MOUSE
NC score	0.124414 (rank : 549)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	525	Target Neighborhood Hits	178	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

CLC4F_HUMAN
NC score	0.123922 (rank : 550)	θ value	3.0926 (rank : 429)
Query Neighborhood Hits	525	Target Neighborhood Hits	513	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

LCE3A_HUMAN
NC score	0.123095 (rank : 551)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	525	Target Neighborhood Hits	29	Shared Neighborhood Hits	18
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LRP6_HUMAN
NC score	0.122984 (rank : 552)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	525	Target Neighborhood Hits	235	Shared Neighborhood Hits	115
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MEP1B_HUMAN
NC score	0.122912 (rank : 553)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	525	Target Neighborhood Hits	98	Shared Neighborhood Hits	56
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MKS3_MOUSE
NC score	0.122417 (rank : 554)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

CO7_HUMAN
NC score	0.122102 (rank : 555)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	525	Target Neighborhood Hits	278	Shared Neighborhood Hits	127
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CORIN_MOUSE
NC score	0.121311 (rank : 556)	θ value	0.279714 (rank : 305)
Query Neighborhood Hits	525	Target Neighborhood Hits	451	Shared Neighborhood Hits	163
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

LRP6_MOUSE
NC score	0.121111 (rank : 557)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	525	Target Neighborhood Hits	232	Shared Neighborhood Hits	112
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP5_MOUSE
NC score	0.120992 (rank : 558)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	525	Target Neighborhood Hits	236	Shared Neighborhood Hits	111
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

CLC5A_MOUSE
NC score	0.120885 (rank : 559)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R007, Q3UV97, Q8BL24	Gene names	Clec5a, Clecsf5, Mdl1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 5 member A (C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin protein) (MDL-1).

NRG2_MOUSE
NC score	0.120321 (rank : 560)	θ value	0.365318 (rank : 321)
Query Neighborhood Hits	525	Target Neighborhood Hits	392	Shared Neighborhood Hits	105
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

ENTK_HUMAN
NC score	0.119472 (rank : 561)	θ value	0.0113563 (rank : 187)
Query Neighborhood Hits	525	Target Neighborhood Hits	310	Shared Neighborhood Hits	84
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

PERT_HUMAN
NC score	0.118489 (rank : 562)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	525	Target Neighborhood Hits	221	Shared Neighborhood Hits	110
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

LRP5_HUMAN
NC score	0.118330 (rank : 563)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	525	Target Neighborhood Hits	224	Shared Neighborhood Hits	106
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

BTBD9_HUMAN
NC score	0.117218 (rank : 564)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	525	Target Neighborhood Hits	163	Shared Neighborhood Hits	56
SwissProt Accessions	Q96Q07, Q96M00	Gene names	BTBD9, KIAA1880
Domain Architecture
Description	BTB/POZ domain-containing protein 9.

BTBD9_MOUSE
NC score	0.116342 (rank : 565)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	525	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C726	Gene names	Btbd9
Domain Architecture
Description	BTB/POZ domain-containing protein 9.

KRA24_HUMAN
NC score	0.116145 (rank : 566)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	525	Target Neighborhood Hits	192	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

NKG2A_HUMAN
NC score	0.115797 (rank : 567)	θ value	2.36792 (rank : 421)
Query Neighborhood Hits	525	Target Neighborhood Hits	94	Shared Neighborhood Hits	52
SwissProt Accessions	P26715	Gene names	KLRC1, NKG2A
Domain Architecture
Description	NKG2-A/NKG2-B type II integral membrane protein (NKG2-A/B-activating NK receptor) (NK cell receptor A) (CD159a antigen).

TNR25_HUMAN
NC score	0.114893 (rank : 568)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	525	Target Neighborhood Hits	172	Shared Neighborhood Hits	71
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

MT1L_HUMAN
NC score	0.113313 (rank : 569)	θ value	1.38821 (rank : 390)
Query Neighborhood Hits	525	Target Neighborhood Hits	73	Shared Neighborhood Hits	42
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

KLRBC_MOUSE
NC score	0.113244 (rank : 570)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	525	Target Neighborhood Hits	101	Shared Neighborhood Hits	55
SwissProt Accessions	P27814	Gene names	Klrb1c, Ly55-c, Ly55c
Domain Architecture
Description	Natural killer cell surface protein P1-40 (NKR-P1 40) (NKR-P1.9).

MMRN1_HUMAN
NC score	0.112953 (rank : 571)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	525	Target Neighborhood Hits	636	Shared Neighborhood Hits	135
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MUC2_HUMAN
NC score	0.112610 (rank : 572)	θ value	0.813845 (rank : 354)
Query Neighborhood Hits	525	Target Neighborhood Hits	906	Shared Neighborhood Hits	148
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MT4_HUMAN
NC score	0.112384 (rank : 573)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	525	Target Neighborhood Hits	83	Shared Neighborhood Hits	53
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

FA7_MOUSE
NC score	0.111329 (rank : 574)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	525	Target Neighborhood Hits	374	Shared Neighborhood Hits	160
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

ASTL_HUMAN
NC score	0.110825 (rank : 575)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	525	Target Neighborhood Hits	252	Shared Neighborhood Hits	16
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

CD320_HUMAN
NC score	0.109930 (rank : 576)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	525	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

UROL1_MOUSE
NC score	0.109905 (rank : 577)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	525	Target Neighborhood Hits	235	Shared Neighborhood Hits	103
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

REG1B_HUMAN
NC score	0.109788 (rank : 578)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	57
SwissProt Accessions	P48304	Gene names	REG1B, REGL
Domain Architecture
Description	Lithostathine 1 beta precursor (Regenerating protein I beta).

ASTL_MOUSE
NC score	0.109731 (rank : 579)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	525	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

NKG2C_HUMAN
NC score	0.109632 (rank : 580)	θ value	6.88961 (rank : 495)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	P26717, O43802, Q9NR42	Gene names	KLRC2, NKG2C
Domain Architecture
Description	NKG2-C type II integral membrane protein (NKG2-C-activating NK receptor) (NK cell receptor C) (CD159c antigen).

BMPER_HUMAN
NC score	0.109593 (rank : 581)	θ value	0.62314 (rank : 332)
Query Neighborhood Hits	525	Target Neighborhood Hits	175	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

MT1E_HUMAN
NC score	0.109480 (rank : 582)	θ value	1.81305 (rank : 405)
Query Neighborhood Hits	525	Target Neighborhood Hits	75	Shared Neighborhood Hits	52
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

PGH2_MOUSE
NC score	0.109037 (rank : 583)	θ value	1.06291 (rank : 374)
Query Neighborhood Hits	525	Target Neighborhood Hits	113	Shared Neighborhood Hits	85
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PERT_MOUSE
NC score	0.108957 (rank : 584)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	525	Target Neighborhood Hits	221	Shared Neighborhood Hits	105
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

LIT1_MOUSE
NC score	0.107818 (rank : 585)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	525	Target Neighborhood Hits	114	Shared Neighborhood Hits	53
SwissProt Accessions	P43137	Gene names	Reg1
Domain Architecture
Description	Lithostathine 1 precursor (Pancreatic stone protein 1) (PSP) (Pancreatic thread protein 1) (PTP) (Islet of Langerhans regenerating protein 1) (REG 1).

LIT2_MOUSE
NC score	0.107557 (rank : 586)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	525	Target Neighborhood Hits	111	Shared Neighborhood Hits	51
SwissProt Accessions	Q08731	Gene names	Reg2
Domain Architecture
Description	Lithostathine 2 precursor (Pancreatic stone protein 2) (PSP) (Pancreatic thread protein 2) (PTP) (Islet of Langerhans regenerating protein 2) (REG 2).

BMPER_MOUSE
NC score	0.106946 (rank : 587)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	107
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

TNR14_HUMAN
NC score	0.106600 (rank : 588)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	525	Target Neighborhood Hits	149	Shared Neighborhood Hits	68
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

SHBG_HUMAN
NC score	0.106465 (rank : 589)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	525	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

KLRBA_MOUSE
NC score	0.106073 (rank : 590)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	525	Target Neighborhood Hits	104	Shared Neighborhood Hits	55
SwissProt Accessions	P27811	Gene names	Klrb1a, Ly55, Ly55a
Domain Architecture
Description	Natural killer cell surface protein P1-2 (NKR-P1 2) (NKR-P1.7).

KR413_HUMAN
NC score	0.105582 (rank : 591)	θ value	6.88961 (rank : 490)
Query Neighborhood Hits	525	Target Neighborhood Hits	112	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

MUC13_HUMAN
NC score	0.105058 (rank : 592)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	525	Target Neighborhood Hits	164	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

NRG1_HUMAN
NC score	0.104371 (rank : 593)	θ value	8.99809 (rank : 520)
Query Neighborhood Hits	525	Target Neighborhood Hits	285	Shared Neighborhood Hits	86
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

REG1A_HUMAN
NC score	0.103869 (rank : 594)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	525	Target Neighborhood Hits	112	Shared Neighborhood Hits	49
SwissProt Accessions	P05451, P11379	Gene names	REG1A, PSPS, REG
Domain Architecture
Description	Lithostathine 1 alpha precursor (Pancreatic stone protein) (PSP) (Pancreatic thread protein) (PTP) (Islet of Langerhans regenerating protein) (REG) (Regenerating protein I alpha) (Islet cells regeneration factor) (ICRF).

OLR1_MOUSE
NC score	0.103853 (rank : 595)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	525	Target Neighborhood Hits	596	Shared Neighborhood Hits	68
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

MT2_MOUSE
NC score	0.102131 (rank : 596)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	525	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

TNR7_HUMAN
NC score	0.101277 (rank : 597)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	64
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

BTBD2_HUMAN
NC score	0.101192 (rank : 598)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	525	Target Neighborhood Hits	161	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BX70, O60418, O75248, Q7Z5W0, Q96SX8, Q9NPS1, Q9NX81	Gene names	BTBD2
Domain Architecture
Description	BTB/POZ domain-containing protein 2.

SHBG_MOUSE
NC score	0.100925 (rank : 599)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	525	Target Neighborhood Hits	50	Shared Neighborhood Hits	35
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

LORI_MOUSE
NC score	0.100674 (rank : 600)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	525	Target Neighborhood Hits	47	Shared Neighborhood Hits	22
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

RECK_HUMAN
NC score	0.100674 (rank : 601)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	525	Target Neighborhood Hits	189	Shared Neighborhood Hits	91
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

BTBD8_HUMAN
NC score	0.100021 (rank : 602)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	525	Target Neighborhood Hits	146	Shared Neighborhood Hits	50
SwissProt Accessions	Q5XKL5, Q6V9S5	Gene names	BTBD8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 8.

CD72_HUMAN
NC score	0.099960 (rank : 603)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	525	Target Neighborhood Hits	345	Shared Neighborhood Hits	53
SwissProt Accessions	P21854	Gene names	CD72
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2).

FINC_HUMAN
NC score	0.099884 (rank : 604)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	525	Target Neighborhood Hits	302	Shared Neighborhood Hits	57
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
NC score	0.098349 (rank : 605)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	525	Target Neighborhood Hits	309	Shared Neighborhood Hits	60
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

UROL1_HUMAN
NC score	0.097875 (rank : 606)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	525	Target Neighborhood Hits	213	Shared Neighborhood Hits	98
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

TNR22_MOUSE
NC score	0.097069 (rank : 607)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	525	Target Neighborhood Hits	97	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

LCE2C_HUMAN
NC score	0.096981 (rank : 608)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	525	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

BTBD6_HUMAN
NC score	0.096792 (rank : 609)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	525	Target Neighborhood Hits	121	Shared Neighborhood Hits	54
SwissProt Accessions	Q96KE9, Q8IVQ7, Q9BR94	Gene names	BTBD6, BDPL
Domain Architecture
Description	BTB/POZ domain-containing protein 6 (Lens BTB domain protein).

ADA11_MOUSE
NC score	0.096716 (rank : 610)	θ value	5.27518 (rank : 467)
Query Neighborhood Hits	525	Target Neighborhood Hits	263	Shared Neighborhood Hits	156
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

BTBD1_HUMAN
NC score	0.096634 (rank : 611)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	525	Target Neighborhood Hits	127	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H0C5, Q9BX71, Q9NWN4	Gene names	BTBD1, C15orf1
Domain Architecture
Description	BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A- transactivated protein 8) (NS5ATP8).

ADA11_HUMAN
NC score	0.096466 (rank : 612)	θ value	5.27518 (rank : 466)
Query Neighborhood Hits	525	Target Neighborhood Hits	259	Shared Neighborhood Hits	155
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

BTBD6_MOUSE
NC score	0.096312 (rank : 613)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	525	Target Neighborhood Hits	125	Shared Neighborhood Hits	54
SwissProt Accessions	Q8K2J9	Gene names	Btbd6
Domain Architecture
Description	BTB/POZ domain-containing protein 6.

ODFP_MOUSE
NC score	0.095536 (rank : 614)	θ value	6.88961 (rank : 496)
Query Neighborhood Hits	525	Target Neighborhood Hits	75	Shared Neighborhood Hits	41
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

BTBD3_HUMAN
NC score	0.094904 (rank : 615)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	525	Target Neighborhood Hits	127	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2F9	Gene names	BTBD3, KIAA0952
Domain Architecture
Description	BTB/POZ domain-containing protein 3.

LCE2A_HUMAN
NC score	0.094879 (rank : 616)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	525	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

FSTL3_HUMAN
NC score	0.094788 (rank : 617)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	525	Target Neighborhood Hits	162	Shared Neighborhood Hits	88
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

BTBD3_MOUSE
NC score	0.094754 (rank : 618)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	525	Target Neighborhood Hits	124	Shared Neighborhood Hits	54
SwissProt Accessions	P58545	Gene names	Btbd3
Domain Architecture
Description	BTB/POZ domain-containing protein 3.

TECTA_MOUSE
NC score	0.094615 (rank : 619)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	525	Target Neighborhood Hits	244	Shared Neighborhood Hits	134
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

SPOP_HUMAN
NC score	0.094430 (rank : 620)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	525	Target Neighborhood Hits	168	Shared Neighborhood Hits	53
SwissProt Accessions	O43791	Gene names	SPOP
Domain Architecture
Description	Speckle-type POZ protein.

SPOP_MOUSE
NC score	0.094430 (rank : 621)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	525	Target Neighborhood Hits	168	Shared Neighborhood Hits	53
SwissProt Accessions	Q6ZWS8	Gene names	Spop, Pcif1
Domain Architecture	No domain graphic available
Description	Speckle-type POZ protein (PDX-1 C-terminal-interacting factor 1) (PCIF1).

CO8B_MOUSE
NC score	0.094378 (rank : 622)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	525	Target Neighborhood Hits	224	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

TPA_MOUSE
NC score	0.094178 (rank : 623)	θ value	5.27518 (rank : 481)
Query Neighborhood Hits	525	Target Neighborhood Hits	335	Shared Neighborhood Hits	154
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

MT1_MOUSE
NC score	0.093797 (rank : 624)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	525	Target Neighborhood Hits	72	Shared Neighborhood Hits	43
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

VASN_HUMAN
NC score	0.093363 (rank : 625)	θ value	0.813845 (rank : 360)
Query Neighborhood Hits	525	Target Neighborhood Hits	449	Shared Neighborhood Hits	131
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ADA15_MOUSE
NC score	0.092726 (rank : 626)	θ value	3.0926 (rank : 425)
Query Neighborhood Hits	525	Target Neighborhood Hits	324	Shared Neighborhood Hits	166
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

TPA_HUMAN
NC score	0.092093 (rank : 627)	θ value	6.88961 (rank : 502)
Query Neighborhood Hits	525	Target Neighborhood Hits	324	Shared Neighborhood Hits	152
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

NRG2_HUMAN
NC score	0.091574 (rank : 628)	θ value	4.03905 (rank : 458)
Query Neighborhood Hits	525	Target Neighborhood Hits	419	Shared Neighborhood Hits	91
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

LCE2D_HUMAN
NC score	0.091504 (rank : 629)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	525	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

NKG2E_HUMAN
NC score	0.091163 (rank : 630)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	525	Target Neighborhood Hits	96	Shared Neighborhood Hits	51
SwissProt Accessions	Q07444, Q96RL0, Q9UP04	Gene names	KLRC3, NKG2E
Domain Architecture
Description	NKG2-E type II integral membrane protein (NKG2-E-activating NK receptor) (NK cell receptor E).

TDPZ1_MOUSE
NC score	0.091004 (rank : 631)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	525	Target Neighborhood Hits	164	Shared Neighborhood Hits	53
SwissProt Accessions	Q717B3, Q71G58, Q8BZV7, Q8VI39	Gene names	Tdpoz1, 2cpoz56, Mapp2, Spopl1
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 1 (MAPP family protein 2).

C4BB_HUMAN
NC score	0.090874 (rank : 632)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	525	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

BTBD1_MOUSE
NC score	0.090611 (rank : 633)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	525	Target Neighborhood Hits	114	Shared Neighborhood Hits	51
SwissProt Accessions	P58544, Q8BTZ0, Q8K0J0	Gene names	Btbd1, Gsrp
Domain Architecture
Description	BTB/POZ domain-containing protein 1 (Glucose signal repressing protein).

CD302_MOUSE
NC score	0.089684 (rank : 634)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	525	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DCG2, Q78KD8, Q9D0X7	Gene names	Cd302, Clec13a
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (Type I transmembrane C-type lectin receptor DCL-1).

MKS3_HUMAN
NC score	0.089036 (rank : 635)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	525	Target Neighborhood Hits	79	Shared Neighborhood Hits	60
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

PAPPA_MOUSE
NC score	0.088953 (rank : 636)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	525	Target Neighborhood Hits	153	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

REG3G_MOUSE
NC score	0.088132 (rank : 637)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	46
SwissProt Accessions	O09049	Gene names	Reg3g, Pap3
Domain Architecture
Description	Regenerating islet-derived protein 3 gamma precursor (Reg III-gamma) (Pancreatitis-associated protein 3).

EMR3_HUMAN
NC score	0.087922 (rank : 638)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	525	Target Neighborhood Hits	245	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

TDPZ4_MOUSE
NC score	0.087802 (rank : 639)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	525	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q6YCH2	Gene names	Tdpoz4
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 4.

ADA23_HUMAN
NC score	0.087199 (rank : 640)	θ value	1.38821 (rank : 379)
Query Neighborhood Hits	525	Target Neighborhood Hits	235	Shared Neighborhood Hits	140
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

REG3A_MOUSE
NC score	0.087062 (rank : 641)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	525	Target Neighborhood Hits	80	Shared Neighborhood Hits	41
SwissProt Accessions	O09037	Gene names	Reg3a, Pap2
Domain Architecture
Description	Regenerating islet-derived protein 3 alpha precursor (Reg III-alpha) (Pancreatitis-associated protein 2) (Lithostathine 3) (Islet of Langerhans regenerating protein 3).

FSTL3_MOUSE
NC score	0.087021 (rank : 642)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	525	Target Neighborhood Hits	152	Shared Neighborhood Hits	81
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

ADA23_MOUSE
NC score	0.086739 (rank : 643)	θ value	1.06291 (rank : 361)
Query Neighborhood Hits	525	Target Neighborhood Hits	245	Shared Neighborhood Hits	145
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

TMPS6_HUMAN
NC score	0.086693 (rank : 644)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	525	Target Neighborhood Hits	338	Shared Neighborhood Hits	126
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

CHODL_HUMAN
NC score	0.086612 (rank : 645)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	525	Target Neighborhood Hits	81	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H9P2, Q7Z798, Q7Z799, Q7Z7A0, Q9HCY3	Gene names	CHODL, C21orf68
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

VEGFC_HUMAN
NC score	0.086418 (rank : 646)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	525	Target Neighborhood Hits	128	Shared Neighborhood Hits	80
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

LCE2B_HUMAN
NC score	0.086336 (rank : 647)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	525	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

PGH2_HUMAN
NC score	0.086259 (rank : 648)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	525	Target Neighborhood Hits	103	Shared Neighborhood Hits	74
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

CLC3A_HUMAN
NC score	0.086191 (rank : 649)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	46
SwissProt Accessions	O75596, Q6UXF5	Gene names	CLEC3A, CLECSF1
Domain Architecture
Description	C-type lectin domain family 3 member A precursor (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin).

ADAM8_HUMAN
NC score	0.085959 (rank : 650)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	525	Target Neighborhood Hits	327	Shared Neighborhood Hits	165
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

MCSP_MOUSE
NC score	0.085914 (rank : 651)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	525	Target Neighborhood Hits	108	Shared Neighborhood Hits	40
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

BACH2_HUMAN
NC score	0.085823 (rank : 652)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	525	Target Neighborhood Hits	234	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

ADA15_HUMAN
NC score	0.085776 (rank : 653)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	525	Target Neighborhood Hits	288	Shared Neighborhood Hits	160
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

PAPPA_HUMAN
NC score	0.085593 (rank : 654)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	525	Target Neighborhood Hits	161	Shared Neighborhood Hits	61
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

CLC3A_MOUSE
NC score	0.085269 (rank : 655)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	525	Target Neighborhood Hits	95	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EPW4	Gene names	Clec3a, Clecsf1
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 3 member A precursor (C-type lectin superfamily member 1) (Cartilage-derived C-type lectin).

NRG4_HUMAN
NC score	0.084797 (rank : 656)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	525	Target Neighborhood Hits	85	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

VASN_MOUSE
NC score	0.084757 (rank : 657)	θ value	0.365318 (rank : 326)
Query Neighborhood Hits	525	Target Neighborhood Hits	426	Shared Neighborhood Hits	124
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ADAM8_MOUSE
NC score	0.084387 (rank : 658)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	525	Target Neighborhood Hits	326	Shared Neighborhood Hits	163
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

CR2_HUMAN
NC score	0.084338 (rank : 659)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	28
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

CR2_MOUSE
NC score	0.084055 (rank : 660)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	525	Target Neighborhood Hits	101	Shared Neighborhood Hits	29
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

CR1_HUMAN
NC score	0.083632 (rank : 661)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	525	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

NRG4_MOUSE
NC score	0.083611 (rank : 662)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	525	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

RECK_MOUSE
NC score	0.083085 (rank : 663)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	525	Target Neighborhood Hits	158	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TETN_HUMAN
NC score	0.082949 (rank : 664)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	P05452	Gene names	CLEC3B, TNA
Domain Architecture
Description	Tetranectin precursor (TN) (C-type lectin domain family 3 member B) (Plasminogen kringle 4-binding protein).

TDPZ2_MOUSE
NC score	0.082872 (rank : 665)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	525	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q717B2	Gene names	Tdpoz2
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 2.

CO9_MOUSE
NC score	0.082827 (rank : 666)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	525	Target Neighborhood Hits	153	Shared Neighborhood Hits	87
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

REG3B_MOUSE
NC score	0.082754 (rank : 667)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	525	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	P35230	Gene names	Reg3b, Pap, Pap1
Domain Architecture
Description	Regenerating islet-derived protein 3 beta precursor (Reg III-beta) (Pancreatitis-associated protein 1).

TDPZ3_MOUSE
NC score	0.082739 (rank : 668)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	525	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	Q717B4	Gene names	Tdpoz3
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 3.

TNR19_MOUSE
NC score	0.082491 (rank : 669)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

CHODL_MOUSE
NC score	0.082329 (rank : 670)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	525	Target Neighborhood Hits	80	Shared Neighborhood Hits	40
SwissProt Accessions	Q9CXM0, Q8VI31	Gene names	Chodl
Domain Architecture
Description	Chondrolectin precursor (Transmembrane protein MT75).

TECTA_HUMAN
NC score	0.082040 (rank : 671)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	525	Target Neighborhood Hits	239	Shared Neighborhood Hits	122
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TDPZ5_MOUSE
NC score	0.081589 (rank : 672)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	525	Target Neighborhood Hits	160	Shared Neighborhood Hits	53
SwissProt Accessions	Q6YCH1	Gene names	Tdpoz5
Domain Architecture	No domain graphic available
Description	TD and POZ domain-containing protein 5.

BACH1_HUMAN
NC score	0.081319 (rank : 673)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	525	Target Neighborhood Hits	289	Shared Neighborhood Hits	55
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

TMPS6_MOUSE
NC score	0.080993 (rank : 674)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	525	Target Neighborhood Hits	341	Shared Neighborhood Hits	124
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

APR3_MOUSE
NC score	0.080796 (rank : 675)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	525	Target Neighborhood Hits	61	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

KLRA7_MOUSE
NC score	0.080741 (rank : 676)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	54
SwissProt Accessions	Q60654, Q60655, Q60656, Q60683	Gene names	Klra7, Ly-49g, Ly49-g, Ly49g, Ly49g4
Domain Architecture
Description	Killer cell lectin-like receptor 7 (T-cell surface glycoprotein Ly- 49G) (Ly49-G antigen) (Lymphocyte antigen 49G).

BACH1_MOUSE
NC score	0.080615 (rank : 677)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	525	Target Neighborhood Hits	289	Shared Neighborhood Hits	55
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

ADA19_MOUSE
NC score	0.080610 (rank : 678)	θ value	3.0926 (rank : 426)
Query Neighborhood Hits	525	Target Neighborhood Hits	315	Shared Neighborhood Hits	159
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

VEGFC_MOUSE
NC score	0.080504 (rank : 679)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	525	Target Neighborhood Hits	119	Shared Neighborhood Hits	74
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

BACH2_MOUSE
NC score	0.080270 (rank : 680)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	525	Target Neighborhood Hits	248	Shared Neighborhood Hits	56
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

HCFC2_MOUSE
NC score	0.080158 (rank : 681)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	525	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

TNR9_HUMAN
NC score	0.079734 (rank : 682)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	525	Target Neighborhood Hits	166	Shared Neighborhood Hits	78
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

LY49A_MOUSE
NC score	0.079653 (rank : 683)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	55
SwissProt Accessions	P20937	Gene names	Klra1, Ly-49, Ly-49a, Ly49, Ly49A
Domain Architecture
Description	T-cell surface glycoprotein YE1/48 (T lymphocyte antigen A1) (Ly49-A antigen) (Lymphocyte antigen 49A).

CO9_HUMAN
NC score	0.079345 (rank : 684)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	525	Target Neighborhood Hits	147	Shared Neighborhood Hits	80
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

TNR7_MOUSE
NC score	0.079250 (rank : 685)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	525	Target Neighborhood Hits	112	Shared Neighborhood Hits	53
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TMPS7_HUMAN
NC score	0.079003 (rank : 686)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	525	Target Neighborhood Hits	275	Shared Neighborhood Hits	86
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

ADA22_MOUSE
NC score	0.078890 (rank : 687)	θ value	3.0926 (rank : 427)
Query Neighborhood Hits	525	Target Neighborhood Hits	225	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

PGH1_MOUSE
NC score	0.078755 (rank : 688)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	70
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

KLRA3_MOUSE
NC score	0.078025 (rank : 689)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	52
SwissProt Accessions	Q64329, Q61154, Q64257	Gene names	Klra3, Ly-49c, Ly49C
Domain Architecture
Description	Killer cell lectin-like receptor 3 (T-cell surface glycoprotein Ly- 49C) (Ly49-C antigen) (Lymphocyte antigen 49C) (5E6).

KLRA4_MOUSE
NC score	0.077767 (rank : 690)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	53
SwissProt Accessions	Q60651, O78026, Q9EPA5	Gene names	Klra4, Ly-49d, Ly49-d, Ly49d
Domain Architecture
Description	Killer cell lectin-like receptor 4 (T-cell surface glycoprotein Ly- 49D) (Ly49-D antigen) (Lymphocyte antigen 49D).

CD302_HUMAN
NC score	0.076758 (rank : 691)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	525	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IX05, Q15009	Gene names	CD302, CLEC13A, DCL1, KIAA0022
Domain Architecture	No domain graphic available
Description	CD302 antigen precursor (C-type lectin domain family 13 member A) (C- type lectin BIMLEC) (Type I transmembrane C-type lectin receptor DCL- 1).

CLC14_MOUSE
NC score	0.076556 (rank : 692)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

TMPS7_MOUSE
NC score	0.076426 (rank : 693)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	525	Target Neighborhood Hits	275	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

KR124_HUMAN
NC score	0.076020 (rank : 694)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	525	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KLRA6_MOUSE
NC score	0.075900 (rank : 695)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	53
SwissProt Accessions	Q60653	Gene names	Klra6, Ly-49f, Ly49-f, Ly49F
Domain Architecture
Description	Killer cell lectin-like receptor 6 (T-cell surface glycoprotein Ly- 49F) (Ly49-F antigen) (Lymphocyte antigen 49F).

MT1G_HUMAN
NC score	0.075776 (rank : 696)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	525	Target Neighborhood Hits	63	Shared Neighborhood Hits	35
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

PLXA1_HUMAN
NC score	0.075718 (rank : 697)	θ value	0.279714 (rank : 311)
Query Neighborhood Hits	525	Target Neighborhood Hits	108	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

TNR3_MOUSE
NC score	0.075461 (rank : 698)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	525	Target Neighborhood Hits	113	Shared Neighborhood Hits	55
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

WFDC3_HUMAN
NC score	0.075455 (rank : 699)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	525	Target Neighborhood Hits	138	Shared Neighborhood Hits	62
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

SRPX_MOUSE
NC score	0.075362 (rank : 700)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	525	Target Neighborhood Hits	75	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

KLRA5_MOUSE
NC score	0.075337 (rank : 701)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	525	Target Neighborhood Hits	88	Shared Neighborhood Hits	52
SwissProt Accessions	Q60652	Gene names	Klra5, Ly-49e, Ly49-e, Ly49e
Domain Architecture
Description	Killer cell lectin-like receptor 5 (T-cell surface glycoprotein Ly- 49E) (Ly49-E antigen) (Lymphocyte antigen 49E).

CLC14_HUMAN
NC score	0.075241 (rank : 702)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	525	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

PLXA3_HUMAN
NC score	0.075035 (rank : 703)	θ value	0.0252991 (rank : 213)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	P51805	Gene names	PLXNA3, PLXN4, SEX
Domain Architecture
Description	Plexin-A3 precursor (Plexin-4) (Semaphorin receptor SEX).

PLXA4_MOUSE
NC score	0.074678 (rank : 704)	θ value	0.0736092 (rank : 252)
Query Neighborhood Hits	525	Target Neighborhood Hits	109	Shared Neighborhood Hits	28
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

SRPX_HUMAN
NC score	0.073932 (rank : 705)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	525	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

PLXA1_MOUSE
NC score	0.073862 (rank : 706)	θ value	0.365318 (rank : 323)
Query Neighborhood Hits	525	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	P70206, Q5DTR0	Gene names	Plxna1, KIAA4053
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Plexin-1) (Plex 1).

MBL2_MOUSE
NC score	0.073785 (rank : 707)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	525	Target Neighborhood Hits	148	Shared Neighborhood Hits	42
SwissProt Accessions	P41317	Gene names	Mbl2
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (Mannan-binding protein) (RA-reactive factor P28A subunit) (RARF/P28A).

C4BP_MOUSE
NC score	0.073525 (rank : 708)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	23
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

PLXA4_HUMAN
NC score	0.072975 (rank : 709)	θ value	0.0736092 (rank : 251)
Query Neighborhood Hits	525	Target Neighborhood Hits	106	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

ABTB1_HUMAN
NC score	0.072974 (rank : 710)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	525	Target Neighborhood Hits	325	Shared Neighborhood Hits	58
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

REG3G_HUMAN
NC score	0.072867 (rank : 711)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	525	Target Neighborhood Hits	86	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UW15, Q6FH18	Gene names	REG3G, PAP1B
Domain Architecture	No domain graphic available
Description	Regenerating islet-derived protein 3 gamma precursor (Reg III-gamma) (Pancreatitis-associated protein 1B) (PAP IB).

MBL2_HUMAN
NC score	0.072831 (rank : 712)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	525	Target Neighborhood Hits	161	Shared Neighborhood Hits	42
SwissProt Accessions	P11226, Q86SI4, Q96KE4, Q96TF7, Q96TF8, Q96TF9	Gene names	MBL2, MBL
Domain Architecture
Description	Mannose-binding protein C precursor (MBP-C) (MBP1) (Mannan-binding protein) (Mannose-binding lectin).

KR122_HUMAN
NC score	0.072725 (rank : 713)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	525	Target Neighborhood Hits	97	Shared Neighborhood Hits	57
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

MBL1_MOUSE
NC score	0.072514 (rank : 714)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	525	Target Neighborhood Hits	147	Shared Neighborhood Hits	40
SwissProt Accessions	P39039	Gene names	Mbl1
Domain Architecture
Description	Mannose-binding protein A precursor (MBP-A) (Mannan-binding protein) (Ra-reactive factor polysaccharide-binding component p28B polypeptide) (RaRF p28B).

PLXA2_HUMAN
NC score	0.072486 (rank : 715)	θ value	0.21417 (rank : 300)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	O75051, Q6UX61, Q96GN9, Q9BRL1, Q9UIW1	Gene names	PLXNA2, KIAA0463, OCT
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Semaphorin receptor OCT).

CO8B_HUMAN
NC score	0.072362 (rank : 716)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	525	Target Neighborhood Hits	199	Shared Neighborhood Hits	87
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

KR241_HUMAN
NC score	0.072327 (rank : 717)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	525	Target Neighborhood Hits	71	Shared Neighborhood Hits	43
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

REG3A_HUMAN
NC score	0.072212 (rank : 718)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	525	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	Q06141	Gene names	REG3A, HIP, PAP, PAP1
Domain Architecture
Description	Regenerating islet-derived protein 3 alpha precursor (Reg III-alpha) (Pancreatitis-associated protein 1).

PLXA2_MOUSE
NC score	0.072123 (rank : 719)	θ value	0.279714 (rank : 312)
Query Neighborhood Hits	525	Target Neighborhood Hits	97	Shared Neighborhood Hits	24
SwissProt Accessions	P70207, Q6NVE6, Q6PHN4, Q80TZ7, Q8R1I4	Gene names	Plxna2, Kiaa0463
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Plexin-2) (Plex 2).

CRAC1_MOUSE
NC score	0.071911 (rank : 720)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	525	Target Neighborhood Hits	112	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

KLRA8_MOUSE
NC score	0.071889 (rank : 721)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	53
SwissProt Accessions	Q60682, O78027	Gene names	Klra8, Ly-49h, Ly49-h, Ly49H
Domain Architecture
Description	Killer cell lectin-like receptor 8 (T-cell surface glycoprotein Ly- 49H) (Ly49-H antigen) (Lymphocyte antigen 49H).

FREM1_HUMAN
NC score	0.071625 (rank : 722)	θ value	8.99809 (rank : 509)
Query Neighborhood Hits	525	Target Neighborhood Hits	170	Shared Neighborhood Hits	56
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

MCP_MOUSE
NC score	0.071287 (rank : 723)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	525	Target Neighborhood Hits	79	Shared Neighborhood Hits	24
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

ADA19_HUMAN
NC score	0.071277 (rank : 724)	θ value	8.99809 (rank : 505)
Query Neighborhood Hits	525	Target Neighborhood Hits	381	Shared Neighborhood Hits	147
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

EREG_HUMAN
NC score	0.071274 (rank : 725)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	525	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ADAM9_MOUSE
NC score	0.071067 (rank : 726)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	525	Target Neighborhood Hits	325	Shared Neighborhood Hits	157
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

TNR5_MOUSE
NC score	0.070601 (rank : 727)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	525	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

CRAC1_HUMAN
NC score	0.070576 (rank : 728)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	525	Target Neighborhood Hits	111	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

ZNFX1_HUMAN
NC score	0.070367 (rank : 729)	θ value	5.27518 (rank : 483)
Query Neighborhood Hits	525	Target Neighborhood Hits	308	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

TNR8_MOUSE
NC score	0.070339 (rank : 730)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	525	Target Neighborhood Hits	208	Shared Neighborhood Hits	68
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

C4BP_HUMAN
NC score	0.070293 (rank : 731)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	525	Target Neighborhood Hits	92	Shared Neighborhood Hits	27
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

APR3_HUMAN
NC score	0.070140 (rank : 732)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	525	Target Neighborhood Hits	50	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

ADA33_MOUSE
NC score	0.070118 (rank : 733)	θ value	1.06291 (rank : 362)
Query Neighborhood Hits	525	Target Neighborhood Hits	231	Shared Neighborhood Hits	131
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

PLXC1_MOUSE
NC score	0.069723 (rank : 734)	θ value	0.813845 (rank : 357)
Query Neighborhood Hits	525	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QZC2, Q8CGW1	Gene names	Plxnc1, Vespr
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

CRRY_MOUSE
NC score	0.069696 (rank : 735)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	525	Target Neighborhood Hits	84	Shared Neighborhood Hits	22
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

CO8A_HUMAN
NC score	0.069539 (rank : 736)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	525	Target Neighborhood Hits	200	Shared Neighborhood Hits	91
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ADA22_HUMAN
NC score	0.069485 (rank : 737)	θ value	4.03905 (rank : 443)
Query Neighborhood Hits	525	Target Neighborhood Hits	211	Shared Neighborhood Hits	120
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

LCE3B_HUMAN
NC score	0.069425 (rank : 738)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	525	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

PLXD1_HUMAN
NC score	0.068652 (rank : 739)	θ value	1.06291 (rank : 376)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

ZP3R_MOUSE
NC score	0.068591 (rank : 740)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	525	Target Neighborhood Hits	81	Shared Neighborhood Hits	23
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

CFAH_HUMAN
NC score	0.068548 (rank : 741)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	525	Target Neighborhood Hits	101	Shared Neighborhood Hits	29
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

PHXR5_MOUSE
NC score	0.068397 (rank : 742)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PGH1_HUMAN
NC score	0.067989 (rank : 743)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	525	Target Neighborhood Hits	91	Shared Neighborhood Hits	64
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

ADA33_HUMAN
NC score	0.067848 (rank : 744)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	525	Target Neighborhood Hits	264	Shared Neighborhood Hits	138
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

MT1F_HUMAN
NC score	0.067815 (rank : 745)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	525	Target Neighborhood Hits	73	Shared Neighborhood Hits	45
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

APOH_MOUSE
NC score	0.067791 (rank : 746)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	525	Target Neighborhood Hits	74	Shared Neighborhood Hits	20
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

FST_MOUSE
NC score	0.067698 (rank : 747)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	525	Target Neighborhood Hits	146	Shared Neighborhood Hits	63
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

TETN_MOUSE
NC score	0.067531 (rank : 748)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	525	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	P43025	Gene names	Clec3b, Tna
Domain Architecture
Description	Tetranectin precursor (TN) (C-type lectin domain family 3 member B) (Plasminogen kringle 4-binding protein).

GMCL1_MOUSE
NC score	0.067441 (rank : 749)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	525	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	Q920G9, Q9DBW5, Q9QUP6	Gene names	Gmcl1, Gcl, Gcl1
Domain Architecture
Description	Germ cell-less protein-like 1 (mGcl-1) (DP-interacting protein) (DIP).

GMCL1_HUMAN
NC score	0.066873 (rank : 750)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	525	Target Neighborhood Hits	85	Shared Neighborhood Hits	41
SwissProt Accessions	Q96IK5, Q9H826, Q9H8V7, Q9H927	Gene names	GMCL1, GCL
Domain Architecture
Description	Germ cell-less protein-like 1.

DAF1_MOUSE
NC score	0.066868 (rank : 751)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	525	Target Neighborhood Hits	204	Shared Neighborhood Hits	30
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

ABTB1_MOUSE
NC score	0.066649 (rank : 752)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	525	Target Neighborhood Hits	349	Shared Neighborhood Hits	58
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

MATN1_HUMAN
NC score	0.066595 (rank : 753)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	78
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

CFAH_MOUSE
NC score	0.066474 (rank : 754)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	525	Target Neighborhood Hits	112	Shared Neighborhood Hits	27
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

PLXB3_HUMAN
NC score	0.066261 (rank : 755)	θ value	0.813845 (rank : 356)
Query Neighborhood Hits	525	Target Neighborhood Hits	106	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

ADAM9_HUMAN
NC score	0.066132 (rank : 756)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	525	Target Neighborhood Hits	243	Shared Neighborhood Hits	142
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

MCP_HUMAN
NC score	0.066121 (rank : 757)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	525	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

FREM1_MOUSE
NC score	0.065996 (rank : 758)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	525	Target Neighborhood Hits	163	Shared Neighborhood Hits	52
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

ZNFX1_MOUSE
NC score	0.065980 (rank : 759)	θ value	8.99809 (rank : 525)
Query Neighborhood Hits	525	Target Neighborhood Hits	407	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

APOH_HUMAN
NC score	0.065772 (rank : 760)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	525	Target Neighborhood Hits	75	Shared Neighborhood Hits	17
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

CSPG4_HUMAN
NC score	0.065304 (rank : 761)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	525	Target Neighborhood Hits	112	Shared Neighborhood Hits	33
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

MATN1_MOUSE
NC score	0.065303 (rank : 762)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	525	Target Neighborhood Hits	186	Shared Neighborhood Hits	74
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

PLXB3_MOUSE
NC score	0.065293 (rank : 763)	θ value	1.06291 (rank : 375)
Query Neighborhood Hits	525	Target Neighborhood Hits	94	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

MT2_HUMAN
NC score	0.065160 (rank : 764)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	525	Target Neighborhood Hits	69	Shared Neighborhood Hits	45
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

HPLN2_MOUSE
NC score	0.065145 (rank : 765)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

F13B_MOUSE
NC score	0.065133 (rank : 766)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	525	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

FST_HUMAN
NC score	0.064862 (rank : 767)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	525	Target Neighborhood Hits	129	Shared Neighborhood Hits	52
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

DAF2_MOUSE
NC score	0.064818 (rank : 768)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	525	Target Neighborhood Hits	114	Shared Neighborhood Hits	25
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

ADAM2_MOUSE
NC score	0.064753 (rank : 769)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	525	Target Neighborhood Hits	209	Shared Neighborhood Hits	121
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADA10_HUMAN
NC score	0.064453 (rank : 770)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	525	Target Neighborhood Hits	189	Shared Neighborhood Hits	94
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

HPLN2_HUMAN
NC score	0.064406 (rank : 771)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	525	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

UROK_MOUSE
NC score	0.064054 (rank : 772)	θ value	6.88961 (rank : 503)
Query Neighborhood Hits	525	Target Neighborhood Hits	273	Shared Neighborhood Hits	115
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

CSPG4_MOUSE
NC score	0.063944 (rank : 773)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	525	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

PLXB2_HUMAN
NC score	0.063824 (rank : 774)	θ value	0.279714 (rank : 313)
Query Neighborhood Hits	525	Target Neighborhood Hits	94	Shared Neighborhood Hits	19
SwissProt Accessions	O15031, Q7KZU3, Q9BSU7	Gene names	PLXNB2, KIAA0315
Domain Architecture	No domain graphic available
Description	Plexin-B2 precursor (MM1).

ADA18_MOUSE
NC score	0.063761 (rank : 775)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	525	Target Neighborhood Hits	227	Shared Neighborhood Hits	134
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

F13B_HUMAN
NC score	0.063579 (rank : 776)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	525	Target Neighborhood Hits	84	Shared Neighborhood Hits	27
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

DAF_HUMAN
NC score	0.063340 (rank : 777)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	525	Target Neighborhood Hits	97	Shared Neighborhood Hits	23
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

CO8A_MOUSE
NC score	0.063219 (rank : 778)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	525	Target Neighborhood Hits	182	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

RSPO4_HUMAN
NC score	0.062965 (rank : 779)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	525	Target Neighborhood Hits	110	Shared Neighborhood Hits	55
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RHBT3_HUMAN
NC score	0.062572 (rank : 780)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	525	Target Neighborhood Hits	116	Shared Neighborhood Hits	46
SwissProt Accessions	O94955, Q8IW06	Gene names	RHOBTB3, KIAA0878
Domain Architecture
Description	Rho-related BTB domain-containing protein 3.

RHBT3_MOUSE
NC score	0.062472 (rank : 781)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	525	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CTN4, Q80X55, Q9CVT0	Gene names	Rhobtb3, Kiaa0878
Domain Architecture
Description	Rho-related BTB domain-containing protein 3.

CO2_HUMAN
NC score	0.062406 (rank : 782)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	525	Target Neighborhood Hits	258	Shared Neighborhood Hits	42
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

RCBT1_MOUSE
NC score	0.062373 (rank : 783)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	525	Target Neighborhood Hits	157	Shared Neighborhood Hits	54
SwissProt Accessions	Q6NXM2, Q8BTZ6, Q8BZV0	Gene names	Rcbtb1
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1).

RCBT1_HUMAN
NC score	0.062365 (rank : 784)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	525	Target Neighborhood Hits	158	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NDN9, Q969U9	Gene names	RCBTB1, CLLD7, E4.5
Domain Architecture	No domain graphic available
Description	RCC1 and BTB domain-containing protein 1 (Regulator of chromosome condensation and BTB domain-containing protein 1) (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein).

CFAB_MOUSE
NC score	0.062172 (rank : 785)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	525	Target Neighborhood Hits	262	Shared Neighborhood Hits	43
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

HPLN3_MOUSE
NC score	0.062082 (rank : 786)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	525	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

MT1I_HUMAN
NC score	0.062024 (rank : 787)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	525	Target Neighborhood Hits	64	Shared Neighborhood Hits	41
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

ABTB2_HUMAN
NC score	0.061801 (rank : 788)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	525	Target Neighborhood Hits	391	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

TNR19_HUMAN
NC score	0.061740 (rank : 789)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

ADA10_MOUSE
NC score	0.061738 (rank : 790)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	525	Target Neighborhood Hits	194	Shared Neighborhood Hits	99
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA32_HUMAN
NC score	0.061721 (rank : 791)	θ value	6.88961 (rank : 484)
Query Neighborhood Hits	525	Target Neighborhood Hits	216	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ODFP_HUMAN
NC score	0.061699 (rank : 792)	θ value	0.365318 (rank : 322)
Query Neighborhood Hits	525	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q14990	Gene names	ODF1, ODFP
Domain Architecture
Description	Outer dense fiber protein.

HPLN4_MOUSE
NC score	0.061594 (rank : 793)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	525	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

TNR3_HUMAN
NC score	0.061306 (rank : 794)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	525	Target Neighborhood Hits	145	Shared Neighborhood Hits	47
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

HPLN4_HUMAN
NC score	0.061106 (rank : 795)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

SFTA1_HUMAN
NC score	0.060649 (rank : 796)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	525	Target Neighborhood Hits	169	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IWL2, P07714, Q5RIR5, Q5RIR7, Q6PIT0, Q8TC19	Gene names	SFTPA1, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A1 precursor (SP-A1) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

HPLN3_HUMAN
NC score	0.060628 (rank : 797)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	525	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

CFAB_HUMAN
NC score	0.060611 (rank : 798)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	525	Target Neighborhood Hits	251	Shared Neighborhood Hits	41
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

EMR4_MOUSE
NC score	0.060549 (rank : 799)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	525	Target Neighborhood Hits	191	Shared Neighborhood Hits	77
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

PAP2_HUMAN
NC score	0.060402 (rank : 800)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	525	Target Neighborhood Hits	106	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

TNR8_HUMAN
NC score	0.060190 (rank : 801)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	525	Target Neighborhood Hits	198	Shared Neighborhood Hits	64
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

ASTN_MOUSE
NC score	0.059937 (rank : 802)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	525	Target Neighborhood Hits	98	Shared Neighborhood Hits	48
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ASTN_HUMAN
NC score	0.059676 (rank : 803)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	525	Target Neighborhood Hits	105	Shared Neighborhood Hits	50
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

MT1M_HUMAN
NC score	0.059645 (rank : 804)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	525	Target Neighborhood Hits	72	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

SFTA2_HUMAN
NC score	0.059531 (rank : 805)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	525	Target Neighborhood Hits	169	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IWL1, P07714, Q5RIR8, Q5RIR9	Gene names	SFTPA2, PSAP, SFTP1, SFTPA
Domain Architecture	No domain graphic available
Description	Pulmonary surfactant-associated protein A2 precursor (SP-A2) (SP-A) (PSP-A) (PSPA) (Alveolar proteinosis protein) (35 kDa pulmonary surfactant-associated protein).

TNR11_HUMAN
NC score	0.059462 (rank : 806)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	525	Target Neighborhood Hits	135	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

HPLN1_MOUSE
NC score	0.059308 (rank : 807)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	525	Target Neighborhood Hits	64	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN1_HUMAN
NC score	0.059114 (rank : 808)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	525	Target Neighborhood Hits	67	Shared Neighborhood Hits	14
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

ADAM7_HUMAN
NC score	0.059017 (rank : 809)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	525	Target Neighborhood Hits	221	Shared Neighborhood Hits	126
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADA28_MOUSE
NC score	0.058996 (rank : 810)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	525	Target Neighborhood Hits	241	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

RSPO4_MOUSE
NC score	0.058920 (rank : 811)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	525	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

GMCLL_HUMAN
NC score	0.058882 (rank : 812)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	525	Target Neighborhood Hits	87	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NEA9, Q8TC88, Q8TC89	Gene names	GMCL1L, GCL
Domain Architecture
Description	Germ cell-less protein-like 1-like.

PLXB1_HUMAN
NC score	0.058684 (rank : 813)	θ value	2.36792 (rank : 423)
Query Neighborhood Hits	525	Target Neighborhood Hits	360	Shared Neighborhood Hits	28
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PLXC1_HUMAN
NC score	0.058477 (rank : 814)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	525	Target Neighborhood Hits	94	Shared Neighborhood Hits	24
SwissProt Accessions	O60486, Q59H25	Gene names	PLXNC1, VESPR
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

TNR26_MOUSE
NC score	0.058265 (rank : 815)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	525	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

UROK_HUMAN
NC score	0.057949 (rank : 816)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	525	Target Neighborhood Hits	272	Shared Neighborhood Hits	111
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

ADA28_HUMAN
NC score	0.057928 (rank : 817)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	525	Target Neighborhood Hits	244	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

TNR6_MOUSE
NC score	0.057822 (rank : 818)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	525	Target Neighborhood Hits	99	Shared Neighborhood Hits	47
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

FNDC3_MOUSE
NC score	0.057689 (rank : 819)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	525	Target Neighborhood Hits	207	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

ABTB2_MOUSE
NC score	0.057680 (rank : 820)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	525	Target Neighborhood Hits	414	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

FHR5_HUMAN
NC score	0.057655 (rank : 821)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	525	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

ADA17_HUMAN
NC score	0.057406 (rank : 822)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	525	Target Neighborhood Hits	223	Shared Neighborhood Hits	97
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

CFAI_MOUSE
NC score	0.057266 (rank : 823)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	525	Target Neighborhood Hits	290	Shared Neighborhood Hits	71
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_HUMAN
NC score	0.057155 (rank : 824)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	525	Target Neighborhood Hits	289	Shared Neighborhood Hits	68
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CHRD_MOUSE
NC score	0.056684 (rank : 825)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

SUSD4_MOUSE
NC score	0.056256 (rank : 826)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	525	Target Neighborhood Hits	122	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

LCE5A_HUMAN
NC score	0.056127 (rank : 827)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	525	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

CO2_MOUSE
NC score	0.055945 (rank : 828)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	525	Target Neighborhood Hits	250	Shared Neighborhood Hits	41
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

SUSD4_HUMAN
NC score	0.055568 (rank : 829)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	525	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

ADM1A_MOUSE
NC score	0.055310 (rank : 830)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	525	Target Neighborhood Hits	230	Shared Neighborhood Hits	128
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

SUSD2_MOUSE
NC score	0.055208 (rank : 831)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	525	Target Neighborhood Hits	104	Shared Neighborhood Hits	32
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

CHRD_HUMAN
NC score	0.055060 (rank : 832)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	525	Target Neighborhood Hits	102	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

EPGN_MOUSE
NC score	0.054892 (rank : 833)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	525	Target Neighborhood Hits	63	Shared Neighborhood Hits	41
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

PLXB1_MOUSE
NC score	0.054748 (rank : 834)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	525	Target Neighborhood Hits	259	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

NRX3B_HUMAN
NC score	0.054324 (rank : 835)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	525	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HDB5	Gene names	NRXN3, KIAA0743
Domain Architecture	No domain graphic available
Description	Neurexin-3-beta precursor (Neurexin III-beta).

SUSD2_HUMAN
NC score	0.053838 (rank : 836)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	525	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

KR111_HUMAN
NC score	0.053775 (rank : 837)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	525	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

ANFY1_MOUSE
NC score	0.053549 (rank : 838)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	525	Target Neighborhood Hits	480	Shared Neighborhood Hits	53
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

LCMT2_MOUSE
NC score	0.053375 (rank : 839)	θ value	1.81305 (rank : 404)
Query Neighborhood Hits	525	Target Neighborhood Hits	33	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BYR1, Q3T9F7, Q6A048, Q8BIG6	Gene names	Lcmt2, Kiaa0547
Domain Architecture	No domain graphic available
Description	Leucine carboxyl methyltransferase 2 (EC 2.1.1.-) (p21WAF1/CIP1 promoter-interacting protein).

ADA24_MOUSE
NC score	0.053307 (rank : 840)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	525	Target Neighborhood Hits	230	Shared Neighborhood Hits	134
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ANFY1_HUMAN
NC score	0.053296 (rank : 841)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	525	Target Neighborhood Hits	480	Shared Neighborhood Hits	52
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

CD72_MOUSE
NC score	0.053233 (rank : 842)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	525	Target Neighborhood Hits	262	Shared Neighborhood Hits	41
SwissProt Accessions	P21855, Q64225	Gene names	Cd72, Ly-32, Lyb-2
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2) (Antigen Ly-32).

SFTPD_MOUSE
NC score	0.052159 (rank : 843)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	525	Target Neighborhood Hits	217	Shared Neighborhood Hits	40
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

FNDC3_HUMAN
NC score	0.052088 (rank : 844)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	525	Target Neighborhood Hits	196	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

SFTPA_MOUSE
NC score	0.051925 (rank : 845)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	525	Target Neighborhood Hits	169	Shared Neighborhood Hits	38
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

TR19L_MOUSE
NC score	0.051777 (rank : 846)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	525	Target Neighborhood Hits	85	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

DKK3_MOUSE
NC score	0.051603 (rank : 847)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	525	Target Neighborhood Hits	83	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

ADA25_MOUSE
NC score	0.051577 (rank : 848)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	525	Target Neighborhood Hits	213	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

BTC_MOUSE
NC score	0.051316 (rank : 849)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	525	Target Neighborhood Hits	67	Shared Neighborhood Hits	44
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

SPIT1_HUMAN
NC score	0.051235 (rank : 850)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	525	Target Neighborhood Hits	100	Shared Neighborhood Hits	34
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

NRX1B_HUMAN
NC score	0.051152 (rank : 851)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	525	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

RSPO3_HUMAN
NC score	0.051149 (rank : 852)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	525	Target Neighborhood Hits	128	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

TNR6B_HUMAN
NC score	0.051066 (rank : 853)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	525	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

LRP11_MOUSE
NC score	0.050893 (rank : 854)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	525	Target Neighborhood Hits	81	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

TNR1B_HUMAN
NC score	0.050837 (rank : 855)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	525	Target Neighborhood Hits	127	Shared Neighborhood Hits	47
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

LRP11_HUMAN
NC score	0.050819 (rank : 856)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	525	Target Neighborhood Hits	82	Shared Neighborhood Hits	30
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

XLKD1_HUMAN
NC score	0.050666 (rank : 857)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	525	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5Y7, Q8TC18, Q9UNF4	Gene names	XLKD1, CRSBP1, HAR
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Hyaluronic acid receptor) (Extracellular link domain-containing protein 1).

MLL3_MOUSE
NC score	0.048170 (rank : 858)	θ value	0.125558 (rank : 286)
Query Neighborhood Hits	525	Target Neighborhood Hits	1399	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SPY1_HUMAN
NC score	0.047871 (rank : 859)	θ value	0.813845 (rank : 359)
Query Neighborhood Hits	525	Target Neighborhood Hits	64	Shared Neighborhood Hits	39
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

CDA7L_HUMAN
NC score	0.046333 (rank : 860)	θ value	0.279714 (rank : 303)
Query Neighborhood Hits	525	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	Q96GN5, Q6PIL4, Q86YT0, Q8IXN5, Q96C70, Q9H9A2, Q9NPV2	Gene names	CDCA7L, HR1, JPO2, R1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2).

MLL3_HUMAN
NC score	0.043898 (rank : 861)	θ value	0.163984 (rank : 294)
Query Neighborhood Hits	525	Target Neighborhood Hits	1644	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL4_HUMAN
NC score	0.042019 (rank : 862)	θ value	0.0330416 (rank : 225)
Query Neighborhood Hits	525	Target Neighborhood Hits	722	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

EPHB4_HUMAN
NC score	0.039421 (rank : 863)	θ value	1.38821 (rank : 382)
Query Neighborhood Hits	525	Target Neighborhood Hits	1056	Shared Neighborhood Hits	117
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

PROP_MOUSE
NC score	0.038344 (rank : 864)	θ value	8.99809 (rank : 522)
Query Neighborhood Hits	525	Target Neighborhood Hits	165	Shared Neighborhood Hits	38
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

THYG_MOUSE
NC score	0.038002 (rank : 865)	θ value	1.38821 (rank : 396)
Query Neighborhood Hits	525	Target Neighborhood Hits	161	Shared Neighborhood Hits	53
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

MGAT3_HUMAN
NC score	0.037422 (rank : 866)	θ value	5.27518 (rank : 476)
Query Neighborhood Hits	525	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	Q09327, Q6IC49, Q9UH32	Gene names	MGAT3, GGNT3
Domain Architecture
Description	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase III) (N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III).

CDCA7_MOUSE
NC score	0.035947 (rank : 867)	θ value	3.0926 (rank : 428)
Query Neighborhood Hits	525	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D0M2, Q3TIS1, Q3U511, Q6NZE5, Q8C1A0	Gene names	Cdca7
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated protein 7.

MGAT3_MOUSE
NC score	0.035233 (rank : 868)	θ value	5.27518 (rank : 477)
Query Neighborhood Hits	525	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	Q10470, P70386	Gene names	Mgat3
Domain Architecture
Description	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase III) (N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III).

C163B_HUMAN
NC score	0.032329 (rank : 869)	θ value	5.27518 (rank : 468)
Query Neighborhood Hits	525	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

HRX_HUMAN
NC score	0.029869 (rank : 870)	θ value	0.279714 (rank : 307)
Query Neighborhood Hits	525	Target Neighborhood Hits	825	Shared Neighborhood Hits	17
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SEM4D_MOUSE
NC score	0.028629 (rank : 871)	θ value	0.0736092 (rank : 253)
Query Neighborhood Hits	525	Target Neighborhood Hits	143	Shared Neighborhood Hits	23
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

EPHB6_HUMAN
NC score	0.028013 (rank : 872)	θ value	1.06291 (rank : 366)
Query Neighborhood Hits	525	Target Neighborhood Hits	912	Shared Neighborhood Hits	78
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

TFF2_HUMAN
NC score	0.027243 (rank : 873)	θ value	1.81305 (rank : 411)
Query Neighborhood Hits	525	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q03403, Q15854	Gene names	TFF2, SML1
Domain Architecture
Description	Trefoil factor 2 precursor (Spasmolytic polypeptide) (SP) (Spasmolysin).

PSCA_MOUSE
NC score	0.027114 (rank : 874)	θ value	4.03905 (rank : 461)
Query Neighborhood Hits	525	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P57096	Gene names	Psca
Domain Architecture	No domain graphic available
Description	Prostate stem cell antigen precursor.

EPHB4_MOUSE
NC score	0.025668 (rank : 875)	θ value	3.0926 (rank : 432)
Query Neighborhood Hits	525	Target Neighborhood Hits	1013	Shared Neighborhood Hits	101
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

SEM4D_HUMAN
NC score	0.025007 (rank : 876)	θ value	0.47712 (rank : 331)
Query Neighborhood Hits	525	Target Neighborhood Hits	139	Shared Neighborhood Hits	21
SwissProt Accessions	Q92854, Q7Z5S4	Gene names	SEMA4D, CD100
Domain Architecture
Description	Semaphorin-4D precursor (Leukocyte activation antigen CD100) (BB18) (A8) (GR3).

PCDA6_HUMAN
NC score	0.024388 (rank : 877)	θ value	0.62314 (rank : 342)
Query Neighborhood Hits	525	Target Neighborhood Hits	187	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UN73, O75283, Q9NRT8	Gene names	PCDHA6
Domain Architecture
Description	Protocadherin alpha 6 precursor (PCDH-alpha6).

PCDA5_HUMAN
NC score	0.024046 (rank : 878)	θ value	0.813845 (rank : 355)
Query Neighborhood Hits	525	Target Neighborhood Hits	217	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

PCDA7_HUMAN
NC score	0.023369 (rank : 879)	θ value	1.38821 (rank : 393)
Query Neighborhood Hits	525	Target Neighborhood Hits	221	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UN72, O75282	Gene names	PCDHA7
Domain Architecture
Description	Protocadherin alpha 7 precursor (PCDH-alpha7).

CDA7L_MOUSE
NC score	0.022259 (rank : 880)	θ value	8.99809 (rank : 507)
Query Neighborhood Hits	525	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q922M5	Gene names	Cdca7l
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Transcription factor RAM2).

PCDA3_HUMAN
NC score	0.021840 (rank : 881)	θ value	5.27518 (rank : 479)
Query Neighborhood Hits	525	Target Neighborhood Hits	203	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5H8, O75286	Gene names	PCDHA3
Domain Architecture
Description	Protocadherin alpha 3 precursor (PCDH-alpha3).

PCDA8_HUMAN
NC score	0.021802 (rank : 882)	θ value	3.0926 (rank : 438)
Query Neighborhood Hits	525	Target Neighborhood Hits	187	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5H6, O75281	Gene names	PCDHA8
Domain Architecture
Description	Protocadherin alpha 8 precursor (PCDH-alpha8).

PCDAD_HUMAN
NC score	0.021787 (rank : 883)	θ value	6.88961 (rank : 497)
Query Neighborhood Hits	525	Target Neighborhood Hits	197	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5I0, O75277	Gene names	PCDHA13
Domain Architecture
Description	Protocadherin alpha 13 precursor (PCDH-alpha13).

PCDAA_HUMAN
NC score	0.021485 (rank : 884)	θ value	4.03905 (rank : 459)
Query Neighborhood Hits	525	Target Neighborhood Hits	183	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5I2, O75280, Q9NRU2	Gene names	PCDHA10
Domain Architecture
Description	Protocadherin alpha 10 precursor (PCDH-alpha10).

PCDA4_HUMAN
NC score	0.021457 (rank : 885)	θ value	8.99809 (rank : 521)
Query Neighborhood Hits	525	Target Neighborhood Hits	193	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UN74, O75285	Gene names	PCDHA4
Domain Architecture
Description	Protocadherin alpha 4 precursor (PCDH-alpha4).

K1333_HUMAN
NC score	0.020333 (rank : 886)	θ value	8.99809 (rank : 511)
Query Neighborhood Hits	525	Target Neighborhood Hits	50	Shared Neighborhood Hits	10
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

EPHA1_HUMAN
NC score	0.020141 (rank : 887)	θ value	6.88961 (rank : 488)
Query Neighborhood Hits	525	Target Neighborhood Hits	997	Shared Neighborhood Hits	94
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

TICN1_HUMAN
NC score	0.019374 (rank : 888)	θ value	4.03905 (rank : 462)
Query Neighborhood Hits	525	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_MOUSE
NC score	0.018913 (rank : 889)	θ value	4.03905 (rank : 463)
Query Neighborhood Hits	525	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

LIPB_HUMAN
NC score	0.016444 (rank : 890)	θ value	5.27518 (rank : 475)
Query Neighborhood Hits	525	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y234	Gene names	LIPT1
Domain Architecture
Description	Lipoyltransferase 1, mitochondrial precursor (EC 6.-.-.-) (Lipoate- protein ligase) (Lipoate biosynthesis protein) (Lipoyl ligase).

IGF1R_HUMAN
NC score	0.015895 (rank : 891)	θ value	5.27518 (rank : 471)
Query Neighborhood Hits	525	Target Neighborhood Hits	977	Shared Neighborhood Hits	94
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

BRCA2_HUMAN
NC score	0.015792 (rank : 892)	θ value	2.36792 (rank : 413)
Query Neighborhood Hits	525	Target Neighborhood Hits	202	Shared Neighborhood Hits	11
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

PXDC2_HUMAN
NC score	0.015785 (rank : 893)	θ value	8.99809 (rank : 523)
Query Neighborhood Hits	525	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UX71, Q96E59, Q96PD9, Q96SU9	Gene names	PLXDC2, TEM7R
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 2 precursor (Tumor endothelial marker 7-related protein).

PHF10_HUMAN
NC score	0.015772 (rank : 894)	θ value	6.88961 (rank : 499)
Query Neighborhood Hits	525	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

ERBB2_MOUSE
NC score	0.013086 (rank : 895)	θ value	8.99809 (rank : 508)
Query Neighborhood Hits	525	Target Neighborhood Hits	918	Shared Neighborhood Hits	72
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

FA45B_HUMAN
NC score	0.013038 (rank : 896)	θ value	5.27518 (rank : 470)
Query Neighborhood Hits	525	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NSW5, Q9NZ36	Gene names	FAM45B
Domain Architecture	No domain graphic available
Description	Protein FAM45B.

ATS1_MOUSE
NC score	0.012835 (rank : 897)	θ value	6.88961 (rank : 485)
Query Neighborhood Hits	525	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

DGKQ_HUMAN
NC score	0.012755 (rank : 898)	θ value	5.27518 (rank : 469)
Query Neighborhood Hits	525	Target Neighborhood Hits	131	Shared Neighborhood Hits	20
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

RNF38_MOUSE
NC score	0.012142 (rank : 899)	θ value	3.0926 (rank : 442)
Query Neighborhood Hits	525	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

ATS1_HUMAN
NC score	0.012125 (rank : 900)	θ value	8.99809 (rank : 506)
Query Neighborhood Hits	525	Target Neighborhood Hits	159	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

RNF38_HUMAN
NC score	0.012118 (rank : 901)	θ value	3.0926 (rank : 441)
Query Neighborhood Hits	525	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

DPOLN_MOUSE
NC score	0.010937 (rank : 902)	θ value	4.03905 (rank : 446)
Query Neighborhood Hits	525	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TQ07, Q3V0L3	Gene names	Poln
Domain Architecture	No domain graphic available
Description	DNA polymerase nu (EC 2.7.7.7).

ZCHC4_MOUSE
NC score	0.010228 (rank : 903)	θ value	8.99809 (rank : 524)
Query Neighborhood Hits	525	Target Neighborhood Hits	63	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKW4, Q3UTX6, Q9D2I1	Gene names	Zcchc4
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 4.

ENPP1_HUMAN
NC score	0.010017 (rank : 904)	θ value	6.88961 (rank : 487)
Query Neighborhood Hits	525	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	P22413, Q5T9R6, Q9NPZ3, Q9P1P6, Q9UP61, Q9Y6K3	Gene names	ENPP1, NPPS, PC1, PDNP1
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

DGKH_HUMAN
NC score	0.007864 (rank : 905)	θ value	4.03905 (rank : 445)
Query Neighborhood Hits	525	Target Neighborhood Hits	255	Shared Neighborhood Hits	17
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

PHLD1_HUMAN
NC score	0.007153 (rank : 906)	θ value	6.88961 (rank : 500)
Query Neighborhood Hits	525	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	P80108, Q15128	Gene names	GPLD1, PIGPLD1
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 1 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

UBP3_MOUSE
NC score	0.002586 (rank : 907)	θ value	4.03905 (rank : 464)
Query Neighborhood Hits	525	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

K1H8_HUMAN
NC score	-0.000451 (rank : 908)	θ value	4.03905 (rank : 451)
Query Neighborhood Hits	525	Target Neighborhood Hits	394	Shared Neighborhood Hits	10
SwissProt Accessions	O76015	Gene names	KRTHA8, HHA8, HKA8
Domain Architecture
Description	Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8).

KPCT_HUMAN
NC score	-0.003468 (rank : 909)	θ value	0.62314 (rank : 337)
Query Neighborhood Hits	525	Target Neighborhood Hits	897	Shared Neighborhood Hits	23
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_MOUSE
NC score	-0.003779 (rank : 910)	θ value	0.62314 (rank : 338)
Query Neighborhood Hits	525	Target Neighborhood Hits	895	Shared Neighborhood Hits	21
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCB_MOUSE
NC score	-0.005372 (rank : 911)	θ value	4.03905 (rank : 454)
Query Neighborhood Hits	525	Target Neighborhood Hits	1117	Shared Neighborhood Hits	22
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_HUMAN
NC score	-0.005380 (rank : 912)	θ value	4.03905 (rank : 453)
Query Neighborhood Hits	525	Target Neighborhood Hits	1121	Shared Neighborhood Hits	22
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCG_HUMAN
NC score	-0.005985 (rank : 913)	θ value	8.99809 (rank : 512)
Query Neighborhood Hits	525	Target Neighborhood Hits	1126	Shared Neighborhood Hits	22
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
NC score	-0.006046 (rank : 914)	θ value	8.99809 (rank : 513)
Query Neighborhood Hits	525	Target Neighborhood Hits	1123	Shared Neighborhood Hits	22
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).