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Network neighborhood for query Sequence : MEP1B_HUMAN

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MEP1B_HUMAN
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MEP1B_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1B_MOUSE
θ value	0 (rank : 2)	NC score	0.978232 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	127	Shared Neighborhood Hits	76
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MEP1A_MOUSE
θ value	7.28896e-151 (rank : 3)	NC score	0.937017 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	166	Shared Neighborhood Hits	77
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1A_HUMAN
θ value	3.06949e-141 (rank : 4)	NC score	0.939359 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	162	Shared Neighborhood Hits	76
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

ASTL_MOUSE
θ value	1.32909e-35 (rank : 5)	NC score	0.793493 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTL_HUMAN
θ value	3.06405e-32 (rank : 6)	NC score	0.742025 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	252	Shared Neighborhood Hits	16
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

TLL1_MOUSE
θ value	5.40856e-29 (rank : 7)	NC score	0.460008 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	237	Shared Neighborhood Hits	44
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	7.06379e-29 (rank : 8)	NC score	0.462265 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	241	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	7.06379e-29 (rank : 9)	NC score	0.458822 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	240	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

BMP1_HUMAN
θ value	1.57365e-28 (rank : 10)	NC score	0.458889 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	233	Shared Neighborhood Hits	42
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL1_HUMAN
θ value	1.57365e-28 (rank : 11)	NC score	0.459974 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	236	Shared Neighborhood Hits	42
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

BMP1_MOUSE
θ value	2.05525e-28 (rank : 12)	NC score	0.457180 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	236	Shared Neighborhood Hits	43
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

MDGA1_HUMAN
θ value	1.09485e-13 (rank : 13)	NC score	0.221718 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	358	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MAMC1_HUMAN
θ value	1.47974e-10 (rank : 14)	NC score	0.203658 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	357	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	1.47974e-10 (rank : 15)	NC score	0.205684 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	357	Shared Neighborhood Hits	21
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

TRAF4_MOUSE
θ value	3.64472e-09 (rank : 16)	NC score	0.256682 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	338	Shared Neighborhood Hits	14
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF4_HUMAN
θ value	1.80886e-08 (rank : 17)	NC score	0.249334 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	373	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

MAMC2_MOUSE
θ value	8.97725e-08 (rank : 18)	NC score	0.355182 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

NRP1_MOUSE
θ value	2.61198e-07 (rank : 19)	NC score	0.281826 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

ENTK_MOUSE
θ value	5.81887e-07 (rank : 20)	NC score	0.133704 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	338	Shared Neighborhood Hits	28
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

NRP1_HUMAN
θ value	7.59969e-07 (rank : 21)	NC score	0.280431 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	119	Shared Neighborhood Hits	23
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

MAMC2_HUMAN
θ value	4.92598e-06 (rank : 22)	NC score	0.343849 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

TRAF2_MOUSE
θ value	5.44631e-05 (rank : 23)	NC score	0.213419 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	394	Shared Neighborhood Hits	14
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

ENTK_HUMAN
θ value	0.000158464 (rank : 24)	NC score	0.130715 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	310	Shared Neighborhood Hits	25
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TRAF2_HUMAN
θ value	0.000270298 (rank : 25)	NC score	0.215445 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	402	Shared Neighborhood Hits	14
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

ZAN_HUMAN
θ value	0.000786445 (rank : 26)	NC score	0.132890 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	679	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

TRAF3_HUMAN
θ value	0.00134147 (rank : 27)	NC score	0.183276 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	463	Shared Neighborhood Hits	15
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	0.00134147 (rank : 28)	NC score	0.182772 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	476	Shared Neighborhood Hits	15
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF5_MOUSE
θ value	0.00175202 (rank : 29)	NC score	0.169183 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	355	Shared Neighborhood Hits	13
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

NRG2_HUMAN
θ value	0.00509761 (rank : 30)	NC score	0.095405 (rank : 104)
Query Neighborhood Hits	98	Target Neighborhood Hits	419	Shared Neighborhood Hits	50
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	0.00509761 (rank : 31)	NC score	0.105679 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	392	Shared Neighborhood Hits	53
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

TRAF6_HUMAN
θ value	0.0113563 (rank : 32)	NC score	0.182818 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	267	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

CSPG5_HUMAN
θ value	0.0148317 (rank : 33)	NC score	0.127953 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	199	Shared Neighborhood Hits	19
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CSPG5_MOUSE
θ value	0.0148317 (rank : 34)	NC score	0.118761 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	211	Shared Neighborhood Hits	12
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

PTPRM_HUMAN
θ value	0.0252991 (rank : 35)	NC score	0.054702 (rank : 232)
Query Neighborhood Hits	98	Target Neighborhood Hits	244	Shared Neighborhood Hits	17
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

NOTC2_HUMAN
θ value	0.0330416 (rank : 36)	NC score	0.095009 (rank : 107)
Query Neighborhood Hits	98	Target Neighborhood Hits	1113	Shared Neighborhood Hits	65
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PROS_HUMAN
θ value	0.0563607 (rank : 37)	NC score	0.115608 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	340	Shared Neighborhood Hits	58
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

ZAN_MOUSE
θ value	0.0563607 (rank : 38)	NC score	0.112683 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	808	Shared Neighborhood Hits	72
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CRUM1_HUMAN
θ value	0.0736092 (rank : 39)	NC score	0.105941 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	457	Shared Neighborhood Hits	62
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

EGF_HUMAN
θ value	0.0736092 (rank : 40)	NC score	0.089847 (rank : 127)
Query Neighborhood Hits	98	Target Neighborhood Hits	343	Shared Neighborhood Hits	58
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

DLK_HUMAN
θ value	0.125558 (rank : 41)	NC score	0.104543 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	401	Shared Neighborhood Hits	56
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

TRAF5_HUMAN
θ value	0.125558 (rank : 42)	NC score	0.156239 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	396	Shared Neighborhood Hits	14
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

NOTC2_MOUSE
θ value	0.163984 (rank : 43)	NC score	0.095473 (rank : 103)
Query Neighborhood Hits	98	Target Neighborhood Hits	1069	Shared Neighborhood Hits	65
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_MOUSE
θ value	0.163984 (rank : 44)	NC score	0.087222 (rank : 136)
Query Neighborhood Hits	98	Target Neighborhood Hits	872	Shared Neighborhood Hits	64
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PTPRM_MOUSE
θ value	0.163984 (rank : 45)	NC score	0.043739 (rank : 257)
Query Neighborhood Hits	98	Target Neighborhood Hits	238	Shared Neighborhood Hits	15
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

TIE2_MOUSE
θ value	0.163984 (rank : 46)	NC score	0.019204 (rank : 264)
Query Neighborhood Hits	98	Target Neighborhood Hits	1204	Shared Neighborhood Hits	53
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

DLK_MOUSE
θ value	0.21417 (rank : 47)	NC score	0.104683 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	374	Shared Neighborhood Hits	55
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

NOTC4_HUMAN
θ value	0.279714 (rank : 48)	NC score	0.086032 (rank : 140)
Query Neighborhood Hits	98	Target Neighborhood Hits	905	Shared Neighborhood Hits	63
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TRAF6_MOUSE
θ value	0.279714 (rank : 49)	NC score	0.161368 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	255	Shared Neighborhood Hits	15
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

CO8B_MOUSE
θ value	0.365318 (rank : 50)	NC score	0.044435 (rank : 256)
Query Neighborhood Hits	98	Target Neighborhood Hits	224	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

SLIT2_MOUSE
θ value	0.365318 (rank : 51)	NC score	0.067195 (rank : 194)
Query Neighborhood Hits	98	Target Neighborhood Hits	684	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

BTC_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.055491 (rank : 227)
Query Neighborhood Hits	98	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

DLL3_HUMAN
θ value	0.47712 (rank : 53)	NC score	0.093201 (rank : 114)
Query Neighborhood Hits	98	Target Neighborhood Hits	419	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	0.47712 (rank : 54)	NC score	0.101119 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	399	Shared Neighborhood Hits	56
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

SLIT2_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.071002 (rank : 181)
Query Neighborhood Hits	98	Target Neighborhood Hits	708	Shared Neighborhood Hits	61
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CELR2_HUMAN
θ value	0.62314 (rank : 56)	NC score	0.051050 (rank : 240)
Query Neighborhood Hits	98	Target Neighborhood Hits	657	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR3_HUMAN
θ value	0.62314 (rank : 57)	NC score	0.049688 (rank : 251)
Query Neighborhood Hits	98	Target Neighborhood Hits	680	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR2_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.046876 (rank : 254)
Query Neighborhood Hits	98	Target Neighborhood Hits	584	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CI126_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.035441 (rank : 259)
Query Neighborhood Hits	98	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N9R8, Q5T163, Q8N1I4	Gene names	C9orf126
Domain Architecture	No domain graphic available
Description	Protein C9orf126.

CI126_MOUSE
θ value	1.38821 (rank : 60)	NC score	0.035426 (rank : 260)
Query Neighborhood Hits	98	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C8N2, Q8C409, Q8C8K2	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf126 homolog.

FATH_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.057581 (rank : 217)
Query Neighborhood Hits	98	Target Neighborhood Hits	570	Shared Neighborhood Hits	60
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TIE2_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.021997 (rank : 262)
Query Neighborhood Hits	98	Target Neighborhood Hits	1192	Shared Neighborhood Hits	61
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

DNER_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.091362 (rank : 119)
Query Neighborhood Hits	98	Target Neighborhood Hits	460	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.090857 (rank : 121)
Query Neighborhood Hits	98	Target Neighborhood Hits	413	Shared Neighborhood Hits	58
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

NOTC1_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.093039 (rank : 115)
Query Neighborhood Hits	98	Target Neighborhood Hits	906	Shared Neighborhood Hits	67
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	1.81305 (rank : 66)	NC score	0.094917 (rank : 108)
Query Neighborhood Hits	98	Target Neighborhood Hits	916	Shared Neighborhood Hits	66
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CRUM2_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.091314 (rank : 120)
Query Neighborhood Hits	98	Target Neighborhood Hits	453	Shared Neighborhood Hits	62
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CSPG2_MOUSE
θ value	2.36792 (rank : 68)	NC score	0.059883 (rank : 212)
Query Neighborhood Hits	98	Target Neighborhood Hits	711	Shared Neighborhood Hits	55
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

DLL1_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.095050 (rank : 106)
Query Neighborhood Hits	98	Target Neighborhood Hits	455	Shared Neighborhood Hits	62
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.086991 (rank : 139)
Query Neighborhood Hits	98	Target Neighborhood Hits	456	Shared Neighborhood Hits	62
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL4_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.090446 (rank : 123)
Query Neighborhood Hits	98	Target Neighborhood Hits	440	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

EGF_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.098041 (rank : 99)
Query Neighborhood Hits	98	Target Neighborhood Hits	358	Shared Neighborhood Hits	61
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

NOTC3_MOUSE
θ value	2.36792 (rank : 73)	NC score	0.090057 (rank : 126)
Query Neighborhood Hits	98	Target Neighborhood Hits	975	Shared Neighborhood Hits	65
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LRP1B_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.087420 (rank : 134)
Query Neighborhood Hits	98	Target Neighborhood Hits	602	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

PROS_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.104746 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	330	Shared Neighborhood Hits	57
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SLIT3_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.073426 (rank : 167)
Query Neighborhood Hits	98	Target Neighborhood Hits	682	Shared Neighborhood Hits	61
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
θ value	3.0926 (rank : 77)	NC score	0.068085 (rank : 192)
Query Neighborhood Hits	98	Target Neighborhood Hits	700	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

ZN198_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.012982 (rank : 266)
Query Neighborhood Hits	98	Target Neighborhood Hits	128	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

CELR3_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.048598 (rank : 252)
Query Neighborhood Hits	98	Target Neighborhood Hits	687	Shared Neighborhood Hits	57
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

ELTD1_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.050625 (rank : 242)
Query Neighborhood Hits	98	Target Neighborhood Hits	288	Shared Neighborhood Hits	51
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

BASI_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.019797 (rank : 263)
Query Neighborhood Hits	98	Target Neighborhood Hits	238	Shared Neighborhood Hits	7
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

CO6_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.027437 (rank : 261)
Query Neighborhood Hits	98	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

DLL4_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.085596 (rank : 141)
Query Neighborhood Hits	98	Target Neighborhood Hits	435	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

EDIL3_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.102537 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	292	Shared Neighborhood Hits	59
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EPHB3_MOUSE
θ value	5.27518 (rank : 85)	NC score	-0.000058 (rank : 271)
Query Neighborhood Hits	98	Target Neighborhood Hits	996	Shared Neighborhood Hits	13
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

NOTC3_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.087160 (rank : 138)
Query Neighborhood Hits	98	Target Neighborhood Hits	1062	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SLIT1_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.072836 (rank : 171)
Query Neighborhood Hits	98	Target Neighborhood Hits	715	Shared Neighborhood Hits	62
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

ATS12_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.004779 (rank : 270)
Query Neighborhood Hits	98	Target Neighborhood Hits	251	Shared Neighborhood Hits	7
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

FA10_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.054056 (rank : 236)
Query Neighborhood Hits	98	Target Neighborhood Hits	435	Shared Neighborhood Hits	63
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FAT2_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.042002 (rank : 258)
Query Neighborhood Hits	98	Target Neighborhood Hits	507	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

STAB2_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.050075 (rank : 247)
Query Neighborhood Hits	98	Target Neighborhood Hits	528	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

CELR1_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.045308 (rank : 255)
Query Neighborhood Hits	98	Target Neighborhood Hits	613	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

LTBP3_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.100560 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	475	Shared Neighborhood Hits	57
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MSH5_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.015469 (rank : 265)
Query Neighborhood Hits	98	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	O43196, O60586, Q5BLU9, Q5SSR1, Q8IW44, Q9BQC7	Gene names	MSH5
Domain Architecture
Description	MutS protein homolog 5.

NRX3A_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.048065 (rank : 253)
Query Neighborhood Hits	98	Target Neighborhood Hits	164	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

RFC3_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.007614 (rank : 269)
Query Neighborhood Hits	98	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R323	Gene names	Rfc3
Domain Architecture
Description	Replication factor C subunit 3 (Replication factor C 38 kDa subunit) (RFC38) (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (RF-C 38 kDa subunit).

SCN2B_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.011432 (rank : 267)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	O60939, O75302, Q9UNN3	Gene names	SCN2B
Domain Architecture
Description	Sodium channel beta-2 subunit precursor.

SCN2B_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.011252 (rank : 268)
Query Neighborhood Hits	98	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q56A07	Gene names	Scn2b
Domain Architecture	No domain graphic available
Description	Sodium channel beta-2 subunit precursor.

AGRIN_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.060706 (rank : 207)
Query Neighborhood Hits	98	Target Neighborhood Hits	582	Shared Neighborhood Hits	55
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ATRN_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.122912 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	525	Shared Neighborhood Hits	56
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.120497 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	519	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

C1QR1_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.080935 (rank : 148)
Query Neighborhood Hits	98	Target Neighborhood Hits	493	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.103626 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	342	Shared Neighborhood Hits	57
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1RA_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.103530 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	379	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.102551 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	380	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.104402 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.100792 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	359	Shared Neighborhood Hits	38
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CD248_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.073243 (rank : 169)
Query Neighborhood Hits	98	Target Neighborhood Hits	679	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.073764 (rank : 165)
Query Neighborhood Hits	98	Target Neighborhood Hits	578	Shared Neighborhood Hits	48
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD97_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.081506 (rank : 147)
Query Neighborhood Hits	98	Target Neighborhood Hits	353	Shared Neighborhood Hits	54
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.055240 (rank : 230)
Query Neighborhood Hits	98	Target Neighborhood Hits	295	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CLC14_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.054435 (rank : 234)
Query Neighborhood Hits	98	Target Neighborhood Hits	143	Shared Neighborhood Hits	29
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.054697 (rank : 233)
Query Neighborhood Hits	98	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CREL1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.058993 (rank : 214)
Query Neighborhood Hits	98	Target Neighborhood Hits	441	Shared Neighborhood Hits	48
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.055427 (rank : 229)
Query Neighborhood Hits	98	Target Neighborhood Hits	524	Shared Neighborhood Hits	48
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.093593 (rank : 113)
Query Neighborhood Hits	98	Target Neighborhood Hits	444	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CS1A_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.102525 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	360	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.102569 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	361	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CSMD1_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.138988 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.137299 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	193	Shared Neighborhood Hits	18
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.142805 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.138361 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	199	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSPG2_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.057741 (rank : 216)
Query Neighborhood Hits	98	Target Neighborhood Hits	681	Shared Neighborhood Hits	54
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG3_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.056989 (rank : 221)
Query Neighborhood Hits	98	Target Neighborhood Hits	676	Shared Neighborhood Hits	53
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.057352 (rank : 219)
Query Neighborhood Hits	98	Target Neighborhood Hits	657	Shared Neighborhood Hits	54
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CUBN_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.187768 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	482	Shared Neighborhood Hits	62
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.190491 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	477	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.158036 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.152725 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	91	Shared Neighborhood Hits	10
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD1_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.108179 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD1_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.111841 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.120729 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	118	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.118709 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DMBT1_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.124753 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.155063 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

EDIL3_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.101115 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	317	Shared Neighborhood Hits	58
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.113589 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	325	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.090280 (rank : 124)
Query Neighborhood Hits	98	Target Neighborhood Hits	287	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.087852 (rank : 132)
Query Neighborhood Hits	98	Target Neighborhood Hits	270	Shared Neighborhood Hits	51
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.092810 (rank : 116)
Query Neighborhood Hits	98	Target Neighborhood Hits	266	Shared Neighborhood Hits	51
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.078053 (rank : 156)
Query Neighborhood Hits	98	Target Neighborhood Hits	365	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.076098 (rank : 162)
Query Neighborhood Hits	98	Target Neighborhood Hits	379	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EMR1_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.070321 (rank : 185)
Query Neighborhood Hits	98	Target Neighborhood Hits	382	Shared Neighborhood Hits	53
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.062103 (rank : 204)
Query Neighborhood Hits	98	Target Neighborhood Hits	349	Shared Neighborhood Hits	53
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.076790 (rank : 161)
Query Neighborhood Hits	98	Target Neighborhood Hits	345	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FA10_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.055846 (rank : 225)
Query Neighborhood Hits	98	Target Neighborhood Hits	431	Shared Neighborhood Hits	59
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.050843 (rank : 241)
Query Neighborhood Hits	98	Target Neighborhood Hits	421	Shared Neighborhood Hits	61
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FBLN1_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.073750 (rank : 166)
Query Neighborhood Hits	98	Target Neighborhood Hits	324	Shared Neighborhood Hits	50
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.074702 (rank : 164)
Query Neighborhood Hits	98	Target Neighborhood Hits	329	Shared Neighborhood Hits	51
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.082201 (rank : 146)
Query Neighborhood Hits	98	Target Neighborhood Hits	392	Shared Neighborhood Hits	54
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.078625 (rank : 155)
Query Neighborhood Hits	98	Target Neighborhood Hits	505	Shared Neighborhood Hits	54
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.079284 (rank : 153)
Query Neighborhood Hits	98	Target Neighborhood Hits	293	Shared Neighborhood Hits	54
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.082763 (rank : 144)
Query Neighborhood Hits	98	Target Neighborhood Hits	279	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.077434 (rank : 159)
Query Neighborhood Hits	98	Target Neighborhood Hits	278	Shared Neighborhood Hits	51
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.076868 (rank : 160)
Query Neighborhood Hits	98	Target Neighborhood Hits	270	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.089505 (rank : 130)
Query Neighborhood Hits	98	Target Neighborhood Hits	329	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.087256 (rank : 135)
Query Neighborhood Hits	98	Target Neighborhood Hits	317	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.095137 (rank : 105)
Query Neighborhood Hits	98	Target Neighborhood Hits	557	Shared Neighborhood Hits	57
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.097942 (rank : 100)
Query Neighborhood Hits	98	Target Neighborhood Hits	563	Shared Neighborhood Hits	58
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.092383 (rank : 118)
Query Neighborhood Hits	98	Target Neighborhood Hits	560	Shared Neighborhood Hits	56
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.092422 (rank : 117)
Query Neighborhood Hits	98	Target Neighborhood Hits	549	Shared Neighborhood Hits	57
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.094527 (rank : 110)
Query Neighborhood Hits	98	Target Neighborhood Hits	543	Shared Neighborhood Hits	57
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.089379 (rank : 131)
Query Neighborhood Hits	98	Target Neighborhood Hits	348	Shared Neighborhood Hits	55
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.089717 (rank : 128)
Query Neighborhood Hits	98	Target Neighborhood Hits	343	Shared Neighborhood Hits	56
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GP126_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.105078 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	187	Shared Neighborhood Hits	16
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

HABP2_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.051093 (rank : 238)
Query Neighborhood Hits	98	Target Neighborhood Hits	431	Shared Neighborhood Hits	55
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.056174 (rank : 224)
Query Neighborhood Hits	98	Target Neighborhood Hits	445	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HMCN1_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.068814 (rank : 189)
Query Neighborhood Hits	98	Target Neighborhood Hits	983	Shared Neighborhood Hits	63
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

JAG1_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.080093 (rank : 152)
Query Neighborhood Hits	98	Target Neighborhood Hits	514	Shared Neighborhood Hits	62
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.077791 (rank : 158)
Query Neighborhood Hits	98	Target Neighborhood Hits	518	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.072351 (rank : 177)
Query Neighborhood Hits	98	Target Neighborhood Hits	491	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.073055 (rank : 170)
Query Neighborhood Hits	98	Target Neighborhood Hits	504	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KREM1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.089544 (rank : 129)
Query Neighborhood Hits	98	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.078005 (rank : 157)
Query Neighborhood Hits	98	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.100509 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.094200 (rank : 111)
Query Neighborhood Hits	98	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LDLR_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.066530 (rank : 197)
Query Neighborhood Hits	98	Target Neighborhood Hits	375	Shared Neighborhood Hits	54
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.062351 (rank : 203)
Query Neighborhood Hits	98	Target Neighborhood Hits	382	Shared Neighborhood Hits	52
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP10_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.050317 (rank : 245)
Query Neighborhood Hits	98	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.138744 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	205	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.139454 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	180	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP1B_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.078754 (rank : 154)
Query Neighborhood Hits	98	Target Neighborhood Hits	606	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.070238 (rank : 186)
Query Neighborhood Hits	98	Target Neighborhood Hits	617	Shared Neighborhood Hits	60
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.067141 (rank : 195)
Query Neighborhood Hits	98	Target Neighborhood Hits	573	Shared Neighborhood Hits	59
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP3_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.105827 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	280	Shared Neighborhood Hits	28
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP4_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.059944 (rank : 211)
Query Neighborhood Hits	98	Target Neighborhood Hits	355	Shared Neighborhood Hits	50
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.060745 (rank : 206)
Query Neighborhood Hits	98	Target Neighborhood Hits	351	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP8_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.072554 (rank : 172)
Query Neighborhood Hits	98	Target Neighborhood Hits	346	Shared Neighborhood Hits	55
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.067862 (rank : 193)
Query Neighborhood Hits	98	Target Neighborhood Hits	385	Shared Neighborhood Hits	53
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.080655 (rank : 150)
Query Neighborhood Hits	98	Target Neighborhood Hits	553	Shared Neighborhood Hits	58
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.084706 (rank : 143)
Query Neighborhood Hits	98	Target Neighborhood Hits	514	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.080836 (rank : 149)
Query Neighborhood Hits	98	Target Neighborhood Hits	502	Shared Neighborhood Hits	58
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.085063 (rank : 142)
Query Neighborhood Hits	98	Target Neighborhood Hits	479	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.082259 (rank : 145)
Query Neighborhood Hits	98	Target Neighborhood Hits	552	Shared Neighborhood Hits	58
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.093778 (rank : 112)
Query Neighborhood Hits	98	Target Neighborhood Hits	617	Shared Neighborhood Hits	57
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.087491 (rank : 133)
Query Neighborhood Hits	98	Target Neighborhood Hits	502	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.080433 (rank : 151)
Query Neighborhood Hits	98	Target Neighborhood Hits	607	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MASP1_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.103184 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	369	Shared Neighborhood Hits	29
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.100999 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.101088 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	364	Shared Neighborhood Hits	30
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.100775 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	382	Shared Neighborhood Hits	34
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MATN1_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.050045 (rank : 250)
Query Neighborhood Hits	98	Target Neighborhood Hits	191	Shared Neighborhood Hits	27
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.051124 (rank : 237)
Query Neighborhood Hits	98	Target Neighborhood Hits	186	Shared Neighborhood Hits	25
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN2_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.090808 (rank : 122)
Query Neighborhood Hits	98	Target Neighborhood Hits	365	Shared Neighborhood Hits	55
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.090260 (rank : 125)
Query Neighborhood Hits	98	Target Neighborhood Hits	356	Shared Neighborhood Hits	52
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.059671 (rank : 213)
Query Neighborhood Hits	98	Target Neighborhood Hits	268	Shared Neighborhood Hits	45
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.060280 (rank : 209)
Query Neighborhood Hits	98	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.075414 (rank : 163)
Query Neighborhood Hits	98	Target Neighborhood Hits	287	Shared Neighborhood Hits	51
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.065236 (rank : 199)
Query Neighborhood Hits	98	Target Neighborhood Hits	277	Shared Neighborhood Hits	47
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MEGF6_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.094872 (rank : 109)
Query Neighborhood Hits	98	Target Neighborhood Hits	671	Shared Neighborhood Hits	60
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MFGM_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.063376 (rank : 200)
Query Neighborhood Hits	98	Target Neighborhood Hits	150	Shared Neighborhood Hits	45
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.073310 (rank : 168)
Query Neighborhood Hits	98	Target Neighborhood Hits	233	Shared Neighborhood Hits	50
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MFRP_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.170509 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	165	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.167957 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MUC13_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.050587 (rank : 243)
Query Neighborhood Hits	98	Target Neighborhood Hits	164	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MUC13_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.070560 (rank : 184)
Query Neighborhood Hits	98	Target Neighborhood Hits	447	Shared Neighborhood Hits	43
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

NELL1_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.068745 (rank : 190)
Query Neighborhood Hits	98	Target Neighborhood Hits	451	Shared Neighborhood Hits	58
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.072498 (rank : 173)
Query Neighborhood Hits	98	Target Neighborhood Hits	449	Shared Neighborhood Hits	56
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.070770 (rank : 182)
Query Neighborhood Hits	98	Target Neighborhood Hits	436	Shared Neighborhood Hits	56
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.175299 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.175596 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	109	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.177549 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.177335 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NID1_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.063140 (rank : 201)
Query Neighborhood Hits	98	Target Neighborhood Hits	329	Shared Neighborhood Hits	54
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.062955 (rank : 202)
Query Neighborhood Hits	98	Target Neighborhood Hits	335	Shared Neighborhood Hits	57
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.070196 (rank : 187)
Query Neighborhood Hits	98	Target Neighborhood Hits	456	Shared Neighborhood Hits	54
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.072486 (rank : 174)
Query Neighborhood Hits	98	Target Neighborhood Hits	338	Shared Neighborhood Hits	54
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NRG1_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.056498 (rank : 223)
Query Neighborhood Hits	98	Target Neighborhood Hits	285	Shared Neighborhood Hits	40
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRP2_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.228130 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.211354 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	113	Shared Neighborhood Hits	21
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PCOC1_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.196792 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	146	Shared Neighborhood Hits	10
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.197140 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.198235 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.200409 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.173346 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.178886 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PGBM_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.054198 (rank : 235)
Query Neighborhood Hits	98	Target Neighborhood Hits	1113	Shared Neighborhood Hits	59
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.051090 (rank : 239)
Query Neighborhood Hits	98	Target Neighborhood Hits	1073	Shared Neighborhood Hits	59
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PHXR5_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.055174 (rank : 231)
Query Neighborhood Hits	98	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PROZ_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.087220 (rank : 137)
Query Neighborhood Hits	98	Target Neighborhood Hits	422	Shared Neighborhood Hits	59
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.096041 (rank : 102)
Query Neighborhood Hits	98	Target Neighborhood Hits	410	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

SCUB3_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.097618 (rank : 101)
Query Neighborhood Hits	98	Target Neighborhood Hits	428	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.098245 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	442	Shared Neighborhood Hits	57
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SEZ6L_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.145573 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	289	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SLIT1_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.069077 (rank : 188)
Query Neighborhood Hits	98	Target Neighborhood Hits	700	Shared Neighborhood Hits	59
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SREC2_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.050053 (rank : 249)
Query Neighborhood Hits	98	Target Neighborhood Hits	645	Shared Neighborhood Hits	49
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.050061 (rank : 248)
Query Neighborhood Hits	98	Target Neighborhood Hits	605	Shared Neighborhood Hits	49
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.050401 (rank : 244)
Query Neighborhood Hits	98	Target Neighborhood Hits	645	Shared Neighborhood Hits	51
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ST14_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.071237 (rank : 180)
Query Neighborhood Hits	98	Target Neighborhood Hits	409	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.070764 (rank : 183)
Query Neighborhood Hits	98	Target Neighborhood Hits	419	Shared Neighborhood Hits	42
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

STAB1_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.057114 (rank : 220)
Query Neighborhood Hits	98	Target Neighborhood Hits	546	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.061579 (rank : 205)
Query Neighborhood Hits	98	Target Neighborhood Hits	566	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.050315 (rank : 246)
Query Neighborhood Hits	98	Target Neighborhood Hits	534	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

SUSD1_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.072484 (rank : 175)
Query Neighborhood Hits	98	Target Neighborhood Hits	285	Shared Neighborhood Hits	54
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TRAF1_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.176297 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	65	Shared Neighborhood Hits	13
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

TRAF1_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.177911 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

TRBM_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.071928 (rank : 179)
Query Neighborhood Hits	98	Target Neighborhood Hits	339	Shared Neighborhood Hits	52
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.072450 (rank : 176)
Query Neighborhood Hits	98	Target Neighborhood Hits	361	Shared Neighborhood Hits	52
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSG6_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.160703 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	91	Shared Neighborhood Hits	12
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.159139 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	91	Shared Neighborhood Hits	12
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSP3_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.056651 (rank : 222)
Query Neighborhood Hits	98	Target Neighborhood Hits	250	Shared Neighborhood Hits	52
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.057522 (rank : 218)
Query Neighborhood Hits	98	Target Neighborhood Hits	247	Shared Neighborhood Hits	52
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.055429 (rank : 228)
Query Neighborhood Hits	98	Target Neighborhood Hits	277	Shared Neighborhood Hits	51
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.058928 (rank : 215)
Query Neighborhood Hits	98	Target Neighborhood Hits	276	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROL1_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.055666 (rank : 226)
Query Neighborhood Hits	98	Target Neighborhood Hits	235	Shared Neighborhood Hits	40
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROM_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.065543 (rank : 198)
Query Neighborhood Hits	98	Target Neighborhood Hits	284	Shared Neighborhood Hits	53
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.072193 (rank : 178)
Query Neighborhood Hits	98	Target Neighborhood Hits	276	Shared Neighborhood Hits	53
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VLDLR_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.060236 (rank : 210)
Query Neighborhood Hits	98	Target Neighborhood Hits	383	Shared Neighborhood Hits	55
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.060381 (rank : 208)
Query Neighborhood Hits	98	Target Neighborhood Hits	360	Shared Neighborhood Hits	54
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

WIF1_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.066591 (rank : 196)
Query Neighborhood Hits	98	Target Neighborhood Hits	392	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.068729 (rank : 191)
Query Neighborhood Hits	98	Target Neighborhood Hits	393	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

Hits sorted by NC score

MEP1B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1B_MOUSE
NC score	0.978232 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	127	Shared Neighborhood Hits	76
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MEP1A_HUMAN
NC score	0.939359 (rank : 3)	θ value	3.06949e-141 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	162	Shared Neighborhood Hits	76
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
NC score	0.937017 (rank : 4)	θ value	7.28896e-151 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	166	Shared Neighborhood Hits	77
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

ASTL_MOUSE
NC score	0.793493 (rank : 5)	θ value	1.32909e-35 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTL_HUMAN
NC score	0.742025 (rank : 6)	θ value	3.06405e-32 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	252	Shared Neighborhood Hits	16
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

TLL2_HUMAN
NC score	0.462265 (rank : 7)	θ value	7.06379e-29 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	241	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_MOUSE
NC score	0.460008 (rank : 8)	θ value	5.40856e-29 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	237	Shared Neighborhood Hits	44
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL1_HUMAN
NC score	0.459974 (rank : 9)	θ value	1.57365e-28 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	236	Shared Neighborhood Hits	42
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

BMP1_HUMAN
NC score	0.458889 (rank : 10)	θ value	1.57365e-28 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	233	Shared Neighborhood Hits	42
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL2_MOUSE
NC score	0.458822 (rank : 11)	θ value	7.06379e-29 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	240	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

BMP1_MOUSE
NC score	0.457180 (rank : 12)	θ value	2.05525e-28 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	236	Shared Neighborhood Hits	43
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

MAMC2_MOUSE
NC score	0.355182 (rank : 13)	θ value	8.97725e-08 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_HUMAN
NC score	0.343849 (rank : 14)	θ value	4.92598e-06 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

NRP1_MOUSE
NC score	0.281826 (rank : 15)	θ value	2.61198e-07 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP1_HUMAN
NC score	0.280431 (rank : 16)	θ value	7.59969e-07 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	119	Shared Neighborhood Hits	23
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

TRAF4_MOUSE
NC score	0.256682 (rank : 17)	θ value	3.64472e-09 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	338	Shared Neighborhood Hits	14
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF4_HUMAN
NC score	0.249334 (rank : 18)	θ value	1.80886e-08 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	373	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

NRP2_HUMAN
NC score	0.228130 (rank : 19)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	98	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

MDGA1_HUMAN
NC score	0.221718 (rank : 20)	θ value	1.09485e-13 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	358	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

TRAF2_HUMAN
NC score	0.215445 (rank : 21)	θ value	0.000270298 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	402	Shared Neighborhood Hits	14
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
NC score	0.213419 (rank : 22)	θ value	5.44631e-05 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	394	Shared Neighborhood Hits	14
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

NRP2_MOUSE
NC score	0.211354 (rank : 23)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	98	Target Neighborhood Hits	113	Shared Neighborhood Hits	21
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

MAMC1_MOUSE
NC score	0.205684 (rank : 24)	θ value	1.47974e-10 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	357	Shared Neighborhood Hits	21
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_HUMAN
NC score	0.203658 (rank : 25)	θ value	1.47974e-10 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	357	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

PCOC2_MOUSE
NC score	0.200409 (rank : 26)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_HUMAN
NC score	0.198235 (rank : 27)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC1_MOUSE
NC score	0.197140 (rank : 28)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	98	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC1_HUMAN
NC score	0.196792 (rank : 29)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	98	Target Neighborhood Hits	146	Shared Neighborhood Hits	10
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

CUBN_MOUSE
NC score	0.190491 (rank : 30)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	98	Target Neighborhood Hits	477	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUBN_HUMAN
NC score	0.187768 (rank : 31)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	98	Target Neighborhood Hits	482	Shared Neighborhood Hits	62
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

TRAF3_HUMAN
NC score	0.183276 (rank : 32)	θ value	0.00134147 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	463	Shared Neighborhood Hits	15
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF6_HUMAN
NC score	0.182818 (rank : 33)	θ value	0.0113563 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	267	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF3_MOUSE
NC score	0.182772 (rank : 34)	θ value	0.00134147 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	476	Shared Neighborhood Hits	15
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

PDGFD_MOUSE
NC score	0.178886 (rank : 35)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	98	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

TRAF1_MOUSE
NC score	0.177911 (rank : 36)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	98	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

NETO2_HUMAN
NC score	0.177549 (rank : 37)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	98	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
NC score	0.177335 (rank : 38)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	98	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

TRAF1_HUMAN
NC score	0.176297 (rank : 39)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	98	Target Neighborhood Hits	65	Shared Neighborhood Hits	13
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

NETO1_MOUSE
NC score	0.175596 (rank : 40)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	98	Target Neighborhood Hits	109	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_HUMAN
NC score	0.175299 (rank : 41)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	98	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

PDGFD_HUMAN
NC score	0.173346 (rank : 42)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

MFRP_HUMAN
NC score	0.170509 (rank : 43)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	98	Target Neighborhood Hits	165	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

TRAF5_MOUSE
NC score	0.169183 (rank : 44)	θ value	0.00175202 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	355	Shared Neighborhood Hits	13
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

MFRP_MOUSE
NC score	0.167957 (rank : 45)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	98	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

TRAF6_MOUSE
NC score	0.161368 (rank : 46)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	255	Shared Neighborhood Hits	15
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TSG6_HUMAN
NC score	0.160703 (rank : 47)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	98	Target Neighborhood Hits	91	Shared Neighborhood Hits	12
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
NC score	0.159139 (rank : 48)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	98	Target Neighborhood Hits	91	Shared Neighborhood Hits	12
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

CUZD1_HUMAN
NC score	0.158036 (rank : 49)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

TRAF5_HUMAN
NC score	0.156239 (rank : 50)	θ value	0.125558 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	396	Shared Neighborhood Hits	14
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

DMBT1_MOUSE
NC score	0.155063 (rank : 51)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	98	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

CUZD1_MOUSE
NC score	0.152725 (rank : 52)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	98	Target Neighborhood Hits	91	Shared Neighborhood Hits	10
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

SEZ6L_HUMAN
NC score	0.145573 (rank : 53)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	98	Target Neighborhood Hits	289	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CSMD2_HUMAN
NC score	0.142805 (rank : 54)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	98	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

LRP12_MOUSE
NC score	0.139454 (rank : 55)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	98	Target Neighborhood Hits	180	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

CSMD1_HUMAN
NC score	0.138988 (rank : 56)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	98	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LRP12_HUMAN
NC score	0.138744 (rank : 57)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	98	Target Neighborhood Hits	205	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

CSMD3_HUMAN
NC score	0.138361 (rank : 58)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	98	Target Neighborhood Hits	199	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSMD1_MOUSE
NC score	0.137299 (rank : 59)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	98	Target Neighborhood Hits	193	Shared Neighborhood Hits	18
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

ENTK_MOUSE
NC score	0.133704 (rank : 60)	θ value	5.81887e-07 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	338	Shared Neighborhood Hits	28
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ZAN_HUMAN
NC score	0.132890 (rank : 61)	θ value	0.000786445 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	679	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ENTK_HUMAN
NC score	0.130715 (rank : 62)	θ value	0.000158464 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	310	Shared Neighborhood Hits	25
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

CSPG5_HUMAN
NC score	0.127953 (rank : 63)	θ value	0.0148317 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	199	Shared Neighborhood Hits	19
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

DMBT1_HUMAN
NC score	0.124753 (rank : 64)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	98	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

ATRN_HUMAN
NC score	0.122912 (rank : 65)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	98	Target Neighborhood Hits	525	Shared Neighborhood Hits	56
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

DCBD2_HUMAN
NC score	0.120729 (rank : 66)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	98	Target Neighborhood Hits	118	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

ATRN_MOUSE
NC score	0.120497 (rank : 67)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	98	Target Neighborhood Hits	519	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CSPG5_MOUSE
NC score	0.118761 (rank : 68)	θ value	0.0148317 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	211	Shared Neighborhood Hits	12
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

DCBD2_MOUSE
NC score	0.118709 (rank : 69)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	98	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

PROS_HUMAN
NC score	0.115608 (rank : 70)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	340	Shared Neighborhood Hits	58
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

EGFL7_HUMAN
NC score	0.113589 (rank : 71)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	98	Target Neighborhood Hits	325	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

ZAN_MOUSE
NC score	0.112683 (rank : 72)	θ value	0.0563607 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	808	Shared Neighborhood Hits	72
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

DCBD1_MOUSE
NC score	0.111841 (rank : 73)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD1_HUMAN
NC score	0.108179 (rank : 74)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	98	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

CRUM1_HUMAN
NC score	0.105941 (rank : 75)	θ value	0.0736092 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	457	Shared Neighborhood Hits	62
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

LRP3_HUMAN
NC score	0.105827 (rank : 76)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	98	Target Neighborhood Hits	280	Shared Neighborhood Hits	28
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

NRG2_MOUSE
NC score	0.105679 (rank : 77)	θ value	0.00509761 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	392	Shared Neighborhood Hits	53
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

GP126_HUMAN
NC score	0.105078 (rank : 78)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	98	Target Neighborhood Hits	187	Shared Neighborhood Hits	16
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

PROS_MOUSE
NC score	0.104746 (rank : 79)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	330	Shared Neighborhood Hits	57
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

DLK_MOUSE
NC score	0.104683 (rank : 80)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	374	Shared Neighborhood Hits	55
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLK_HUMAN
NC score	0.104543 (rank : 81)	θ value	0.125558 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	401	Shared Neighborhood Hits	56
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

C1R_HUMAN
NC score	0.104402 (rank : 82)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	98	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1QR1_MOUSE
NC score	0.103626 (rank : 83)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	98	Target Neighborhood Hits	342	Shared Neighborhood Hits	57
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1RA_MOUSE
NC score	0.103530 (rank : 84)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	98	Target Neighborhood Hits	379	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

MASP1_HUMAN
NC score	0.103184 (rank : 85)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	98	Target Neighborhood Hits	369	Shared Neighborhood Hits	29
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

CS1B_MOUSE
NC score	0.102569 (rank : 86)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	98	Target Neighborhood Hits	361	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

C1RB_MOUSE
NC score	0.102551 (rank : 87)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	98	Target Neighborhood Hits	380	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

EDIL3_HUMAN
NC score	0.102537 (rank : 88)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	292	Shared Neighborhood Hits	59
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

CS1A_MOUSE
NC score	0.102525 (rank : 89)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	98	Target Neighborhood Hits	360	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

DLL3_MOUSE
NC score	0.101119 (rank : 90)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	399	Shared Neighborhood Hits	56
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

EDIL3_MOUSE
NC score	0.101115 (rank : 91)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	98	Target Neighborhood Hits	317	Shared Neighborhood Hits	58
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

MASP2_HUMAN
NC score	0.101088 (rank : 92)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	98	Target Neighborhood Hits	364	Shared Neighborhood Hits	30
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP1_MOUSE
NC score	0.100999 (rank : 93)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	98	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

C1S_HUMAN
NC score	0.100792 (rank : 94)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	98	Target Neighborhood Hits	359	Shared Neighborhood Hits	38
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

MASP2_MOUSE
NC score	0.100775 (rank : 95)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	98	Target Neighborhood Hits	382	Shared Neighborhood Hits	34
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

LTBP3_MOUSE
NC score	0.100560 (rank : 96)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	475	Shared Neighborhood Hits	57
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

KREM2_HUMAN
NC score	0.100509 (rank : 97)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	98	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

SCUB3_MOUSE
NC score	0.098245 (rank : 98)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	98	Target Neighborhood Hits	442	Shared Neighborhood Hits	57
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

EGF_MOUSE
NC score	0.098041 (rank : 99)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	358	Shared Neighborhood Hits	61
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

FBN1_MOUSE
NC score	0.097942 (rank : 100)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	98	Target Neighborhood Hits	563	Shared Neighborhood Hits	58
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

SCUB3_HUMAN
NC score	0.097618 (rank : 101)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	98	Target Neighborhood Hits	428	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

PROZ_MOUSE
NC score	0.096041 (rank : 102)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	98	Target Neighborhood Hits	410	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

NOTC2_MOUSE
NC score	0.095473 (rank : 103)	θ value	0.163984 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	1069	Shared Neighborhood Hits	65
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NRG2_HUMAN
NC score	0.095405 (rank : 104)	θ value	0.00509761 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	419	Shared Neighborhood Hits	50
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

FBN1_HUMAN
NC score	0.095137 (rank : 105)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	98	Target Neighborhood Hits	557	Shared Neighborhood Hits	57
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

DLL1_HUMAN
NC score	0.095050 (rank : 106)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	455	Shared Neighborhood Hits	62
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

NOTC2_HUMAN
NC score	0.095009 (rank : 107)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	1113	Shared Neighborhood Hits	65
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_MOUSE
NC score	0.094917 (rank : 108)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	916	Shared Neighborhood Hits	66
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

MEGF6_HUMAN
NC score	0.094872 (rank : 109)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	98	Target Neighborhood Hits	671	Shared Neighborhood Hits	60
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

FBN3_HUMAN
NC score	0.094527 (rank : 110)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	98	Target Neighborhood Hits	543	Shared Neighborhood Hits	57
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

KREM2_MOUSE
NC score	0.094200 (rank : 111)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	98	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LTBP2_MOUSE
NC score	0.093778 (rank : 112)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	98	Target Neighborhood Hits	617	Shared Neighborhood Hits	57
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CRUM1_MOUSE
NC score	0.093593 (rank : 113)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	98	Target Neighborhood Hits	444	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

DLL3_HUMAN
NC score	0.093201 (rank : 114)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	419	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

NOTC1_HUMAN
NC score	0.093039 (rank : 115)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	906	Shared Neighborhood Hits	67
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

EGFL8_MOUSE
NC score	0.092810 (rank : 116)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	98	Target Neighborhood Hits	266	Shared Neighborhood Hits	51
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

FBN2_MOUSE
NC score	0.092422 (rank : 117)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	98	Target Neighborhood Hits	549	Shared Neighborhood Hits	57
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_HUMAN
NC score	0.092383 (rank : 118)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	98	Target Neighborhood Hits	560	Shared Neighborhood Hits	56
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

DNER_HUMAN
NC score	0.091362 (rank : 119)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	460	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

CRUM2_HUMAN
NC score	0.091314 (rank : 120)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	453	Shared Neighborhood Hits	62
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

DNER_MOUSE
NC score	0.090857 (rank : 121)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	413	Shared Neighborhood Hits	58
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

MATN2_HUMAN
NC score	0.090808 (rank : 122)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	98	Target Neighborhood Hits	365	Shared Neighborhood Hits	55
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

DLL4_MOUSE
NC score	0.090446 (rank : 123)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	440	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

EGFL7_MOUSE
NC score	0.090280 (rank : 124)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	98	Target Neighborhood Hits	287	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

MATN2_MOUSE
NC score	0.090260 (rank : 125)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	98	Target Neighborhood Hits	356	Shared Neighborhood Hits	52
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

NOTC3_MOUSE
NC score	0.090057 (rank : 126)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	975	Shared Neighborhood Hits	65
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

EGF_HUMAN
NC score	0.089847 (rank : 127)	θ value	0.0736092 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	343	Shared Neighborhood Hits	58
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

GAS6_MOUSE
NC score	0.089717 (rank : 128)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	98	Target Neighborhood Hits	343	Shared Neighborhood Hits	56
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

KREM1_HUMAN
NC score	0.089544 (rank : 129)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	98	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

FBLN5_HUMAN
NC score	0.089505 (rank : 130)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	98	Target Neighborhood Hits	329	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

GAS6_HUMAN
NC score	0.089379 (rank : 131)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	98	Target Neighborhood Hits	348	Shared Neighborhood Hits	55
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

EGFL8_HUMAN
NC score	0.087852 (rank : 132)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	98	Target Neighborhood Hits	270	Shared Neighborhood Hits	51
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

LTBP3_HUMAN
NC score	0.087491 (rank : 133)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	98	Target Neighborhood Hits	502	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LRP1B_HUMAN
NC score	0.087420 (rank : 134)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	602	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FBLN5_MOUSE
NC score	0.087256 (rank : 135)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	98	Target Neighborhood Hits	317	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

NOTC4_MOUSE
NC score	0.087222 (rank : 136)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	872	Shared Neighborhood Hits	64
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PROZ_HUMAN
NC score	0.087220 (rank : 137)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	98	Target Neighborhood Hits	422	Shared Neighborhood Hits	59
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

NOTC3_HUMAN
NC score	0.087160 (rank : 138)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	1062	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

DLL1_MOUSE
NC score	0.086991 (rank : 139)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	456	Shared Neighborhood Hits	62
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

NOTC4_HUMAN
NC score	0.086032 (rank : 140)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	905	Shared Neighborhood Hits	63
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

DLL4_HUMAN
NC score	0.085596 (rank : 141)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	435	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

LTB1S_MOUSE
NC score	0.085063 (rank : 142)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	98	Target Neighborhood Hits	479	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
NC score	0.084706 (rank : 143)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	98	Target Neighborhood Hits	514	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBLN3_MOUSE
NC score	0.082763 (rank : 144)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	98	Target Neighborhood Hits	279	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

LTBP2_HUMAN
NC score	0.082259 (rank : 145)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	98	Target Neighborhood Hits	552	Shared Neighborhood Hits	58
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBLN2_HUMAN
NC score	0.082201 (rank : 146)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	98	Target Neighborhood Hits	392	Shared Neighborhood Hits	54
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

CD97_HUMAN
NC score	0.081506 (rank : 147)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	98	Target Neighborhood Hits	353	Shared Neighborhood Hits	54
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

C1QR1_HUMAN
NC score	0.080935 (rank : 148)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	98	Target Neighborhood Hits	493	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

LTB1S_HUMAN
NC score	0.080836 (rank : 149)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	98	Target Neighborhood Hits	502	Shared Neighborhood Hits	58
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.080655 (rank : 150)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	98	Target Neighborhood Hits	553	Shared Neighborhood Hits	58
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP4_MOUSE
NC score	0.080433 (rank : 151)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	98	Target Neighborhood Hits	607	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

JAG1_HUMAN
NC score	0.080093 (rank : 152)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	98	Target Neighborhood Hits	514	Shared Neighborhood Hits	62
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

FBLN3_HUMAN
NC score	0.079284 (rank : 153)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	98	Target Neighborhood Hits	293	Shared Neighborhood Hits	54
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

LRP1B_MOUSE
NC score	0.078754 (rank : 154)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	98	Target Neighborhood Hits	606	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FBLN2_MOUSE
NC score	0.078625 (rank : 155)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	98	Target Neighborhood Hits	505	Shared Neighborhood Hits	54
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

EGFL9_HUMAN
NC score	0.078053 (rank : 156)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	98	Target Neighborhood Hits	365	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

KREM1_MOUSE
NC score	0.078005 (rank : 157)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	98	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

JAG1_MOUSE
NC score	0.077791 (rank : 158)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	98	Target Neighborhood Hits	518	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

FBLN4_HUMAN
NC score	0.077434 (rank : 159)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	98	Target Neighborhood Hits	278	Shared Neighborhood Hits	51
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
NC score	0.076868 (rank : 160)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	98	Target Neighborhood Hits	270	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

EMR2_HUMAN
NC score	0.076790 (rank : 161)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	98	Target Neighborhood Hits	345	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EGFL9_MOUSE
NC score	0.076098 (rank : 162)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	98	Target Neighborhood Hits	379	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

MATN4_HUMAN
NC score	0.075414 (rank : 163)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	98	Target Neighborhood Hits	287	Shared Neighborhood Hits	51
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

FBLN1_MOUSE
NC score	0.074702 (rank : 164)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	98	Target Neighborhood Hits	329	Shared Neighborhood Hits	51
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

CD248_MOUSE
NC score	0.073764 (rank : 165)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	98	Target Neighborhood Hits	578	Shared Neighborhood Hits	48
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

FBLN1_HUMAN
NC score	0.073750 (rank : 166)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	98	Target Neighborhood Hits	324	Shared Neighborhood Hits	50
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

SLIT3_HUMAN
NC score	0.073426 (rank : 167)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	682	Shared Neighborhood Hits	61
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

MFGM_MOUSE
NC score	0.073310 (rank : 168)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	98	Target Neighborhood Hits	233	Shared Neighborhood Hits	50
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

CD248_HUMAN
NC score	0.073243 (rank : 169)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	98	Target Neighborhood Hits	679	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

JAG2_MOUSE
NC score	0.073055 (rank : 170)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	98	Target Neighborhood Hits	504	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

SLIT1_MOUSE
NC score	0.072836 (rank : 171)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	715	Shared Neighborhood Hits	62
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

LRP8_HUMAN
NC score	0.072554 (rank : 172)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	98	Target Neighborhood Hits	346	Shared Neighborhood Hits	55
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

NELL2_HUMAN
NC score	0.072498 (rank : 173)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	98	Target Neighborhood Hits	449	Shared Neighborhood Hits	56
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NID2_MOUSE
NC score	0.072486 (rank : 174)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	98	Target Neighborhood Hits	338	Shared Neighborhood Hits	54
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

SUSD1_HUMAN
NC score	0.072484 (rank : 175)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	98	Target Neighborhood Hits	285	Shared Neighborhood Hits	54
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TRBM_MOUSE
NC score	0.072450 (rank : 176)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	98	Target Neighborhood Hits	361	Shared Neighborhood Hits	52
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

JAG2_HUMAN
NC score	0.072351 (rank : 177)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	98	Target Neighborhood Hits	491	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

UROM_MOUSE
NC score	0.072193 (rank : 178)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	98	Target Neighborhood Hits	276	Shared Neighborhood Hits	53
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

TRBM_HUMAN
NC score	0.071928 (rank : 179)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	98	Target Neighborhood Hits	339	Shared Neighborhood Hits	52
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ST14_HUMAN
NC score	0.071237 (rank : 180)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	98	Target Neighborhood Hits	409	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

SLIT2_HUMAN
NC score	0.071002 (rank : 181)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	708	Shared Neighborhood Hits	61
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

NELL2_MOUSE
NC score	0.070770 (rank : 182)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	98	Target Neighborhood Hits	436	Shared Neighborhood Hits	56
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

ST14_MOUSE
NC score	0.070764 (rank : 183)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	98	Target Neighborhood Hits	419	Shared Neighborhood Hits	42
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

MUC13_MOUSE
NC score	0.070560 (rank : 184)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	98	Target Neighborhood Hits	447	Shared Neighborhood Hits	43
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

EMR1_HUMAN
NC score	0.070321 (rank : 185)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	98	Target Neighborhood Hits	382	Shared Neighborhood Hits	53
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

LRP1_HUMAN
NC score	0.070238 (rank : 186)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	98	Target Neighborhood Hits	617	Shared Neighborhood Hits	60
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

NID2_HUMAN
NC score	0.070196 (rank : 187)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	98	Target Neighborhood Hits	456	Shared Neighborhood Hits	54
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

SLIT1_HUMAN
NC score	0.069077 (rank : 188)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	98	Target Neighborhood Hits	700	Shared Neighborhood Hits	59
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

HMCN1_HUMAN
NC score	0.068814 (rank : 189)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	98	Target Neighborhood Hits	983	Shared Neighborhood Hits	63
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

NELL1_HUMAN
NC score	0.068745 (rank : 190)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	98	Target Neighborhood Hits	451	Shared Neighborhood Hits	58
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

WIF1_MOUSE
NC score	0.068729 (rank : 191)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	98	Target Neighborhood Hits	393	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

SLIT3_MOUSE
NC score	0.068085 (rank : 192)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	700	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

LRP8_MOUSE
NC score	0.067862 (rank : 193)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	98	Target Neighborhood Hits	385	Shared Neighborhood Hits	53
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

SLIT2_MOUSE
NC score	0.067195 (rank : 194)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	684	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LRP2_HUMAN
NC score	0.067141 (rank : 195)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	98	Target Neighborhood Hits	573	Shared Neighborhood Hits	59
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

WIF1_HUMAN
NC score	0.066591 (rank : 196)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	98	Target Neighborhood Hits	392	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

LDLR_HUMAN
NC score	0.066530 (rank : 197)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	98	Target Neighborhood Hits	375	Shared Neighborhood Hits	54
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

UROM_HUMAN
NC score	0.065543 (rank : 198)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	98	Target Neighborhood Hits	284	Shared Neighborhood Hits	53
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

MATN4_MOUSE
NC score	0.065236 (rank : 199)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	98	Target Neighborhood Hits	277	Shared Neighborhood Hits	47
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MFGM_HUMAN
NC score	0.063376 (rank : 200)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	98	Target Neighborhood Hits	150	Shared Neighborhood Hits	45
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

NID1_HUMAN
NC score	0.063140 (rank : 201)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	98	Target Neighborhood Hits	329	Shared Neighborhood Hits	54
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
NC score	0.062955 (rank : 202)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	98	Target Neighborhood Hits	335	Shared Neighborhood Hits	57
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

LDLR_MOUSE
NC score	0.062351 (rank : 203)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	98	Target Neighborhood Hits	382	Shared Neighborhood Hits	52
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

EMR1_MOUSE
NC score	0.062103 (rank : 204)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	98	Target Neighborhood Hits	349	Shared Neighborhood Hits	53
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

STAB1_MOUSE
NC score	0.061579 (rank : 205)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	98	Target Neighborhood Hits	566	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

LRP4_MOUSE
NC score	0.060745 (rank : 206)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	98	Target Neighborhood Hits	351	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

AGRIN_HUMAN
NC score	0.060706 (rank : 207)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	98	Target Neighborhood Hits	582	Shared Neighborhood Hits	55
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

VLDLR_MOUSE
NC score	0.060381 (rank : 208)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	98	Target Neighborhood Hits	360	Shared Neighborhood Hits	54
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

MATN3_MOUSE
NC score	0.060280 (rank : 209)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	98	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

VLDLR_HUMAN
NC score	0.060236 (rank : 210)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	98	Target Neighborhood Hits	383	Shared Neighborhood Hits	55
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LRP4_HUMAN
NC score	0.059944 (rank : 211)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	98	Target Neighborhood Hits	355	Shared Neighborhood Hits	50
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

CSPG2_MOUSE
NC score	0.059883 (rank : 212)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	711	Shared Neighborhood Hits	55
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

MATN3_HUMAN
NC score	0.059671 (rank : 213)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	98	Target Neighborhood Hits	268	Shared Neighborhood Hits	45
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

CREL1_HUMAN
NC score	0.058993 (rank : 214)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	98	Target Neighborhood Hits	441	Shared Neighborhood Hits	48
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

TSP4_MOUSE
NC score	0.058928 (rank : 215)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	98	Target Neighborhood Hits	276	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

CSPG2_HUMAN
NC score	0.057741 (rank : 216)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	98	Target Neighborhood Hits	681	Shared Neighborhood Hits	54
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

FATH_HUMAN
NC score	0.057581 (rank : 217)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	570	Shared Neighborhood Hits	60
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TSP3_MOUSE
NC score	0.057522 (rank : 218)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	98	Target Neighborhood Hits	247	Shared Neighborhood Hits	52
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

CSPG3_MOUSE
NC score	0.057352 (rank : 219)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	98	Target Neighborhood Hits	657	Shared Neighborhood Hits	54
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

STAB1_HUMAN
NC score	0.057114 (rank : 220)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	98	Target Neighborhood Hits	546	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

CSPG3_HUMAN
NC score	0.056989 (rank : 221)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	98	Target Neighborhood Hits	676	Shared Neighborhood Hits	53
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TSP3_HUMAN
NC score	0.056651 (rank : 222)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	98	Target Neighborhood Hits	250	Shared Neighborhood Hits	52
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

NRG1_HUMAN
NC score	0.056498 (rank : 223)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	98	Target Neighborhood Hits	285	Shared Neighborhood Hits	40
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

HABP2_MOUSE
NC score	0.056174 (rank : 224)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	98	Target Neighborhood Hits	445	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

FA10_HUMAN
NC score	0.055846 (rank : 225)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	98	Target Neighborhood Hits	431	Shared Neighborhood Hits	59
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

UROL1_MOUSE
NC score	0.055666 (rank : 226)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	98	Target Neighborhood Hits	235	Shared Neighborhood Hits	40
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

BTC_HUMAN
NC score	0.055491 (rank : 227)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

TSP4_HUMAN
NC score	0.055429 (rank : 228)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	98	Target Neighborhood Hits	277	Shared Neighborhood Hits	51
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

CREL1_MOUSE
NC score	0.055427 (rank : 229)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	98	Target Neighborhood Hits	524	Shared Neighborhood Hits	48
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CD97_MOUSE
NC score	0.055240 (rank : 230)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	98	Target Neighborhood Hits	295	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

PHXR5_MOUSE
NC score	0.055174 (rank : 231)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	98	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PTPRM_HUMAN
NC score	0.054702 (rank : 232)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	244	Shared Neighborhood Hits	17
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

CLC14_MOUSE
NC score	0.054697 (rank : 233)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	98	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CLC14_HUMAN
NC score	0.054435 (rank : 234)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	98	Target Neighborhood Hits	143	Shared Neighborhood Hits	29
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

PGBM_HUMAN
NC score	0.054198 (rank : 235)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	98	Target Neighborhood Hits	1113	Shared Neighborhood Hits	59
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

FA10_MOUSE
NC score	0.054056 (rank : 236)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	435	Shared Neighborhood Hits	63
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

MATN1_MOUSE
NC score	0.051124 (rank : 237)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	98	Target Neighborhood Hits	186	Shared Neighborhood Hits	25
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

HABP2_HUMAN
NC score	0.051093 (rank : 238)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	98	Target Neighborhood Hits	431	Shared Neighborhood Hits	55
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

PGBM_MOUSE
NC score	0.051090 (rank : 239)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	98	Target Neighborhood Hits	1073	Shared Neighborhood Hits	59
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

CELR2_HUMAN
NC score	0.051050 (rank : 240)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	657	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

FA9_HUMAN
NC score	0.050843 (rank : 241)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	98	Target Neighborhood Hits	421	Shared Neighborhood Hits	61
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

ELTD1_MOUSE
NC score	0.050625 (rank : 242)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	288	Shared Neighborhood Hits	51
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

MUC13_HUMAN
NC score	0.050587 (rank : 243)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	98	Target Neighborhood Hits	164	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

SREC_HUMAN
NC score	0.050401 (rank : 244)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	98	Target Neighborhood Hits	645	Shared Neighborhood Hits	51
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LRP10_MOUSE
NC score	0.050317 (rank : 245)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	98	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

STAB2_HUMAN
NC score	0.050315 (rank : 246)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	98	Target Neighborhood Hits	534	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
NC score	0.050075 (rank : 247)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	528	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SREC2_MOUSE
NC score	0.050061 (rank : 248)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	98	Target Neighborhood Hits	605	Shared Neighborhood Hits	49
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC2_HUMAN
NC score	0.050053 (rank : 249)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	98	Target Neighborhood Hits	645	Shared Neighborhood Hits	49
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

MATN1_HUMAN
NC score	0.050045 (rank : 250)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	98	Target Neighborhood Hits	191	Shared Neighborhood Hits	27
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

CELR3_HUMAN
NC score	0.049688 (rank : 251)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	680	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
NC score	0.048598 (rank : 252)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	687	Shared Neighborhood Hits	57
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

NRX3A_HUMAN
NC score	0.048065 (rank : 253)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	164	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

CELR2_MOUSE
NC score	0.046876 (rank : 254)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	584	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR1_HUMAN
NC score	0.045308 (rank : 255)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	613	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CO8B_MOUSE
NC score	0.044435 (rank : 256)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	224	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

PTPRM_MOUSE
NC score	0.043739 (rank : 257)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	238	Shared Neighborhood Hits	15
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

FAT2_HUMAN
NC score	0.042002 (rank : 258)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	507	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

CI126_HUMAN
NC score	0.035441 (rank : 259)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N9R8, Q5T163, Q8N1I4	Gene names	C9orf126
Domain Architecture	No domain graphic available
Description	Protein C9orf126.

CI126_MOUSE
NC score	0.035426 (rank : 260)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C8N2, Q8C409, Q8C8K2	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf126 homolog.

CO6_HUMAN
NC score	0.027437 (rank : 261)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

TIE2_HUMAN
NC score	0.021997 (rank : 262)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	1192	Shared Neighborhood Hits	61
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

BASI_MOUSE
NC score	0.019797 (rank : 263)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	238	Shared Neighborhood Hits	7
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

TIE2_MOUSE
NC score	0.019204 (rank : 264)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	1204	Shared Neighborhood Hits	53
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

MSH5_HUMAN
NC score	0.015469 (rank : 265)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	O43196, O60586, Q5BLU9, Q5SSR1, Q8IW44, Q9BQC7	Gene names	MSH5
Domain Architecture
Description	MutS protein homolog 5.

ZN198_HUMAN
NC score	0.012982 (rank : 266)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	128	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

SCN2B_HUMAN
NC score	0.011432 (rank : 267)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	O60939, O75302, Q9UNN3	Gene names	SCN2B
Domain Architecture
Description	Sodium channel beta-2 subunit precursor.

SCN2B_MOUSE
NC score	0.011252 (rank : 268)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q56A07	Gene names	Scn2b
Domain Architecture	No domain graphic available
Description	Sodium channel beta-2 subunit precursor.

RFC3_MOUSE
NC score	0.007614 (rank : 269)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R323	Gene names	Rfc3
Domain Architecture
Description	Replication factor C subunit 3 (Replication factor C 38 kDa subunit) (RFC38) (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (RF-C 38 kDa subunit).

ATS12_HUMAN
NC score	0.004779 (rank : 270)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	251	Shared Neighborhood Hits	7
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

EPHB3_MOUSE
NC score	-0.000058 (rank : 271)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	996	Shared Neighborhood Hits	13
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).