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Network neighborhood for query Sequence : NOTC4_HUMAN

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NOTC4_HUMAN
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NOTC1_HUMAN
θ value	0 (rank : 1)	NC score	0.980374 (rank : 5)
Query Neighborhood Hits	905	Target Neighborhood Hits	906	Shared Neighborhood Hits	752
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	0 (rank : 2)	NC score	0.971714 (rank : 8)
Query Neighborhood Hits	905	Target Neighborhood Hits	916	Shared Neighborhood Hits	747
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	0 (rank : 3)	NC score	0.975976 (rank : 7)
Query Neighborhood Hits	905	Target Neighborhood Hits	1113	Shared Neighborhood Hits	778
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	0 (rank : 4)	NC score	0.976288 (rank : 6)
Query Neighborhood Hits	905	Target Neighborhood Hits	1069	Shared Neighborhood Hits	767
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	0 (rank : 5)	NC score	0.980901 (rank : 4)
Query Neighborhood Hits	905	Target Neighborhood Hits	1062	Shared Neighborhood Hits	774
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	0 (rank : 6)	NC score	0.982456 (rank : 3)
Query Neighborhood Hits	905	Target Neighborhood Hits	975	Shared Neighborhood Hits	780
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
θ value	0 (rank : 7)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	905	Target Neighborhood Hits	905	Shared Neighborhood Hits	905
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	0 (rank : 8)	NC score	0.993703 (rank : 2)
Query Neighborhood Hits	905	Target Neighborhood Hits	872	Shared Neighborhood Hits	789
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

JAG1_HUMAN
θ value	1.28961e-139 (rank : 9)	NC score	0.858548 (rank : 9)
Query Neighborhood Hits	905	Target Neighborhood Hits	514	Shared Neighborhood Hits	449
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	1.20704e-137 (rank : 10)	NC score	0.857788 (rank : 11)
Query Neighborhood Hits	905	Target Neighborhood Hits	518	Shared Neighborhood Hits	445
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	6.41512e-131 (rank : 11)	NC score	0.857983 (rank : 10)
Query Neighborhood Hits	905	Target Neighborhood Hits	491	Shared Neighborhood Hits	440
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	4.15819e-130 (rank : 12)	NC score	0.855951 (rank : 12)
Query Neighborhood Hits	905	Target Neighborhood Hits	504	Shared Neighborhood Hits	437
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

CRUM1_HUMAN
θ value	1.59483e-97 (rank : 13)	NC score	0.838993 (rank : 17)
Query Neighborhood Hits	905	Target Neighborhood Hits	457	Shared Neighborhood Hits	416
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	1.49272e-95 (rank : 14)	NC score	0.840110 (rank : 15)
Query Neighborhood Hits	905	Target Neighborhood Hits	444	Shared Neighborhood Hits	405
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

FBN3_HUMAN
θ value	9.6755e-95 (rank : 15)	NC score	0.798792 (rank : 30)
Query Neighborhood Hits	905	Target Neighborhood Hits	543	Shared Neighborhood Hits	427
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

MEGF6_HUMAN
θ value	4.65103e-89 (rank : 16)	NC score	0.818515 (rank : 28)
Query Neighborhood Hits	905	Target Neighborhood Hits	671	Shared Neighborhood Hits	491
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

CRUM2_HUMAN
θ value	6.71607e-88 (rank : 17)	NC score	0.844660 (rank : 13)
Query Neighborhood Hits	905	Target Neighborhood Hits	453	Shared Neighborhood Hits	416
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

FBN1_HUMAN
θ value	1.07224e-85 (rank : 18)	NC score	0.795596 (rank : 34)
Query Neighborhood Hits	905	Target Neighborhood Hits	557	Shared Neighborhood Hits	445
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	6.95003e-85 (rank : 19)	NC score	0.796860 (rank : 31)
Query Neighborhood Hits	905	Target Neighborhood Hits	560	Shared Neighborhood Hits	448
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	9.07703e-85 (rank : 20)	NC score	0.796525 (rank : 33)
Query Neighborhood Hits	905	Target Neighborhood Hits	549	Shared Neighborhood Hits	448
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
θ value	1.44917e-82 (rank : 21)	NC score	0.796604 (rank : 32)
Query Neighborhood Hits	905	Target Neighborhood Hits	563	Shared Neighborhood Hits	452
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP4_MOUSE
θ value	3.70236e-70 (rank : 22)	NC score	0.803113 (rank : 29)
Query Neighborhood Hits	905	Target Neighborhood Hits	607	Shared Neighborhood Hits	403
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

DLL1_MOUSE
θ value	2.93355e-67 (rank : 23)	NC score	0.839333 (rank : 16)
Query Neighborhood Hits	905	Target Neighborhood Hits	456	Shared Neighborhood Hits	421
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

LTBP2_MOUSE
θ value	2.93355e-67 (rank : 24)	NC score	0.786350 (rank : 36)
Query Neighborhood Hits	905	Target Neighborhood Hits	617	Shared Neighborhood Hits	412
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

DLL1_HUMAN
θ value	3.24342e-66 (rank : 25)	NC score	0.836397 (rank : 19)
Query Neighborhood Hits	905	Target Neighborhood Hits	455	Shared Neighborhood Hits	412
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

LTBP2_HUMAN
θ value	9.43692e-66 (rank : 26)	NC score	0.786723 (rank : 35)
Query Neighborhood Hits	905	Target Neighborhood Hits	552	Shared Neighborhood Hits	413
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

DNER_HUMAN
θ value	1.2325e-65 (rank : 27)	NC score	0.841115 (rank : 14)
Query Neighborhood Hits	905	Target Neighborhood Hits	460	Shared Neighborhood Hits	396
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	2.74572e-65 (rank : 28)	NC score	0.838774 (rank : 18)
Query Neighborhood Hits	905	Target Neighborhood Hits	413	Shared Neighborhood Hits	384
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

TENX_HUMAN
θ value	4.38363e-63 (rank : 29)	NC score	0.624924 (rank : 99)
Query Neighborhood Hits	905	Target Neighborhood Hits	789	Shared Neighborhood Hits	414
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

DLL4_MOUSE
θ value	3.71096e-62 (rank : 30)	NC score	0.832722 (rank : 20)
Query Neighborhood Hits	905	Target Neighborhood Hits	440	Shared Neighborhood Hits	402
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_HUMAN
θ value	6.32992e-62 (rank : 31)	NC score	0.832333 (rank : 21)
Query Neighborhood Hits	905	Target Neighborhood Hits	435	Shared Neighborhood Hits	399
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

LTBP3_HUMAN
θ value	3.36421e-55 (rank : 32)	NC score	0.778330 (rank : 37)
Query Neighborhood Hits	905	Target Neighborhood Hits	502	Shared Neighborhood Hits	388
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTB1L_MOUSE
θ value	1.66964e-54 (rank : 33)	NC score	0.763754 (rank : 41)
Query Neighborhood Hits	905	Target Neighborhood Hits	514	Shared Neighborhood Hits	403
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	1.66964e-54 (rank : 34)	NC score	0.762971 (rank : 45)
Query Neighborhood Hits	905	Target Neighborhood Hits	479	Shared Neighborhood Hits	381
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SLIT1_HUMAN
θ value	1.19655e-52 (rank : 35)	NC score	0.601215 (rank : 112)
Query Neighborhood Hits	905	Target Neighborhood Hits	700	Shared Neighborhood Hits	385
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

LTB1L_HUMAN
θ value	4.54686e-52 (rank : 36)	NC score	0.764373 (rank : 40)
Query Neighborhood Hits	905	Target Neighborhood Hits	553	Shared Neighborhood Hits	403
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	4.54686e-52 (rank : 37)	NC score	0.763496 (rank : 42)
Query Neighborhood Hits	905	Target Neighborhood Hits	502	Shared Neighborhood Hits	392
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CUBN_HUMAN
θ value	1.11993e-50 (rank : 38)	NC score	0.682551 (rank : 77)
Query Neighborhood Hits	905	Target Neighborhood Hits	482	Shared Neighborhood Hits	385
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

SLIT2_HUMAN
θ value	1.46268e-50 (rank : 39)	NC score	0.592404 (rank : 116)
Query Neighborhood Hits	905	Target Neighborhood Hits	708	Shared Neighborhood Hits	398
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT1_MOUSE
θ value	5.55816e-50 (rank : 40)	NC score	0.601740 (rank : 111)
Query Neighborhood Hits	905	Target Neighborhood Hits	715	Shared Neighborhood Hits	393
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

CUBN_MOUSE
θ value	1.61718e-49 (rank : 41)	NC score	0.685246 (rank : 75)
Query Neighborhood Hits	905	Target Neighborhood Hits	477	Shared Neighborhood Hits	374
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

SLIT2_MOUSE
θ value	1.61718e-49 (rank : 42)	NC score	0.587051 (rank : 120)
Query Neighborhood Hits	905	Target Neighborhood Hits	684	Shared Neighborhood Hits	375
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TENA_HUMAN
θ value	1.61718e-49 (rank : 43)	NC score	0.623551 (rank : 101)
Query Neighborhood Hits	905	Target Neighborhood Hits	631	Shared Neighborhood Hits	393
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	1.15895e-47 (rank : 44)	NC score	0.618639 (rank : 105)
Query Neighborhood Hits	905	Target Neighborhood Hits	596	Shared Neighborhood Hits	386
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

SLIT3_MOUSE
θ value	5.7518e-47 (rank : 45)	NC score	0.578513 (rank : 126)
Query Neighborhood Hits	905	Target Neighborhood Hits	700	Shared Neighborhood Hits	381
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

DLL3_HUMAN
θ value	2.18568e-46 (rank : 46)	NC score	0.820555 (rank : 24)
Query Neighborhood Hits	905	Target Neighborhood Hits	419	Shared Neighborhood Hits	382
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

LTBP3_MOUSE
θ value	2.85459e-46 (rank : 47)	NC score	0.773162 (rank : 38)
Query Neighborhood Hits	905	Target Neighborhood Hits	475	Shared Neighborhood Hits	385
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

SLIT3_HUMAN
θ value	3.15612e-45 (rank : 48)	NC score	0.571383 (rank : 128)
Query Neighborhood Hits	905	Target Neighborhood Hits	682	Shared Neighborhood Hits	362
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

DLL3_MOUSE
θ value	2.04573e-44 (rank : 49)	NC score	0.818795 (rank : 26)
Query Neighborhood Hits	905	Target Neighborhood Hits	399	Shared Neighborhood Hits	371
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

EGFL9_MOUSE
θ value	3.61106e-41 (rank : 50)	NC score	0.819673 (rank : 25)
Query Neighborhood Hits	905	Target Neighborhood Hits	379	Shared Neighborhood Hits	358
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGFL9_HUMAN
θ value	2.34062e-40 (rank : 51)	NC score	0.821058 (rank : 23)
Query Neighborhood Hits	905	Target Neighborhood Hits	365	Shared Neighborhood Hits	351
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

FBLN1_MOUSE
θ value	6.37413e-38 (rank : 52)	NC score	0.726587 (rank : 54)
Query Neighborhood Hits	905	Target Neighborhood Hits	329	Shared Neighborhood Hits	293
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	4.13158e-37 (rank : 53)	NC score	0.739806 (rank : 49)
Query Neighborhood Hits	905	Target Neighborhood Hits	392	Shared Neighborhood Hits	300
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN1_HUMAN
θ value	7.04741e-37 (rank : 54)	NC score	0.726932 (rank : 53)
Query Neighborhood Hits	905	Target Neighborhood Hits	324	Shared Neighborhood Hits	297
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN2_MOUSE
θ value	1.01765e-35 (rank : 55)	NC score	0.734229 (rank : 51)
Query Neighborhood Hits	905	Target Neighborhood Hits	505	Shared Neighborhood Hits	320
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

DLK_HUMAN
θ value	1.73584e-35 (rank : 56)	NC score	0.822034 (rank : 22)
Query Neighborhood Hits	905	Target Neighborhood Hits	401	Shared Neighborhood Hits	381
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	1.46948e-34 (rank : 57)	NC score	0.818735 (rank : 27)
Query Neighborhood Hits	905	Target Neighborhood Hits	374	Shared Neighborhood Hits	361
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

FATH_HUMAN
θ value	1.9192e-34 (rank : 58)	NC score	0.418854 (rank : 373)
Query Neighborhood Hits	905	Target Neighborhood Hits	570	Shared Neighborhood Hits	346
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

HMCN1_HUMAN
θ value	1.37539e-32 (rank : 59)	NC score	0.436349 (rank : 331)
Query Neighborhood Hits	905	Target Neighborhood Hits	983	Shared Neighborhood Hits	334
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

LRP1_HUMAN
θ value	1.98606e-31 (rank : 60)	NC score	0.628727 (rank : 98)
Query Neighborhood Hits	905	Target Neighborhood Hits	617	Shared Neighborhood Hits	452
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

NELL1_HUMAN
θ value	8.3442e-30 (rank : 61)	NC score	0.767730 (rank : 39)
Query Neighborhood Hits	905	Target Neighborhood Hits	451	Shared Neighborhood Hits	391
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

SREC_HUMAN
θ value	3.17079e-29 (rank : 62)	NC score	0.745775 (rank : 48)
Query Neighborhood Hits	905	Target Neighborhood Hits	645	Shared Neighborhood Hits	417
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

SCUB3_MOUSE
θ value	9.2256e-29 (rank : 63)	NC score	0.714777 (rank : 58)
Query Neighborhood Hits	905	Target Neighborhood Hits	442	Shared Neighborhood Hits	321
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LAMA5_HUMAN
θ value	1.57365e-28 (rank : 64)	NC score	0.584226 (rank : 123)
Query Neighborhood Hits	905	Target Neighborhood Hits	976	Shared Neighborhood Hits	399
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LRP1B_HUMAN
θ value	4.57862e-28 (rank : 65)	NC score	0.624195 (rank : 100)
Query Neighborhood Hits	905	Target Neighborhood Hits	602	Shared Neighborhood Hits	460
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SCUB3_HUMAN
θ value	5.97985e-28 (rank : 66)	NC score	0.714946 (rank : 57)
Query Neighborhood Hits	905	Target Neighborhood Hits	428	Shared Neighborhood Hits	312
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

EMR1_MOUSE
θ value	1.12775e-26 (rank : 67)	NC score	0.588726 (rank : 119)
Query Neighborhood Hits	905	Target Neighborhood Hits	349	Shared Neighborhood Hits	263
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

LRP1B_MOUSE
θ value	1.12775e-26 (rank : 68)	NC score	0.620834 (rank : 102)
Query Neighborhood Hits	905	Target Neighborhood Hits	606	Shared Neighborhood Hits	455
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EMR1_HUMAN
θ value	3.28125e-26 (rank : 69)	NC score	0.618953 (rank : 104)
Query Neighborhood Hits	905	Target Neighborhood Hits	382	Shared Neighborhood Hits	288
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

LAMA5_MOUSE
θ value	3.28125e-26 (rank : 70)	NC score	0.595911 (rank : 113)
Query Neighborhood Hits	905	Target Neighborhood Hits	828	Shared Neighborhood Hits	398
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

FBLN3_MOUSE
θ value	7.30988e-26 (rank : 71)	NC score	0.684678 (rank : 76)
Query Neighborhood Hits	905	Target Neighborhood Hits	279	Shared Neighborhood Hits	255
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

LAMB1_MOUSE
θ value	9.54697e-26 (rank : 72)	NC score	0.522093 (rank : 152)
Query Neighborhood Hits	905	Target Neighborhood Hits	919	Shared Neighborhood Hits	321
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SREC2_HUMAN
θ value	4.73814e-25 (rank : 73)	NC score	0.728187 (rank : 52)
Query Neighborhood Hits	905	Target Neighborhood Hits	645	Shared Neighborhood Hits	396
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

FBLN3_HUMAN
θ value	8.08199e-25 (rank : 74)	NC score	0.691586 (rank : 72)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	267
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

NELL2_HUMAN
θ value	8.08199e-25 (rank : 75)	NC score	0.763081 (rank : 43)
Query Neighborhood Hits	905	Target Neighborhood Hits	449	Shared Neighborhood Hits	383
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	8.08199e-25 (rank : 76)	NC score	0.762988 (rank : 44)
Query Neighborhood Hits	905	Target Neighborhood Hits	436	Shared Neighborhood Hits	384
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

SREC2_MOUSE
θ value	8.08199e-25 (rank : 77)	NC score	0.735700 (rank : 50)
Query Neighborhood Hits	905	Target Neighborhood Hits	605	Shared Neighborhood Hits	402
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

FBLN5_HUMAN
θ value	3.07116e-24 (rank : 78)	NC score	0.700552 (rank : 66)
Query Neighborhood Hits	905	Target Neighborhood Hits	329	Shared Neighborhood Hits	297
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

LAMA2_MOUSE
θ value	2.59989e-23 (rank : 79)	NC score	0.498434 (rank : 177)
Query Neighborhood Hits	905	Target Neighborhood Hits	1198	Shared Neighborhood Hits	365
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

ZAN_MOUSE
θ value	3.39556e-23 (rank : 80)	NC score	0.592799 (rank : 115)
Query Neighborhood Hits	905	Target Neighborhood Hits	808	Shared Neighborhood Hits	435
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

MATN2_HUMAN
θ value	4.43474e-23 (rank : 81)	NC score	0.641520 (rank : 94)
Query Neighborhood Hits	905	Target Neighborhood Hits	365	Shared Neighborhood Hits	275
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

ANK3_HUMAN
θ value	5.79196e-23 (rank : 82)	NC score	0.477526 (rank : 218)
Query Neighborhood Hits	905	Target Neighborhood Hits	853	Shared Neighborhood Hits	310
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

LAMA2_HUMAN
θ value	7.56453e-23 (rank : 83)	NC score	0.522516 (rank : 151)
Query Neighborhood Hits	905	Target Neighborhood Hits	1092	Shared Neighborhood Hits	359
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

STAB2_MOUSE
θ value	7.56453e-23 (rank : 84)	NC score	0.707554 (rank : 63)
Query Neighborhood Hits	905	Target Neighborhood Hits	528	Shared Neighborhood Hits	409
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

ANK2_HUMAN
θ value	2.20094e-22 (rank : 85)	NC score	0.445969 (rank : 311)
Query Neighborhood Hits	905	Target Neighborhood Hits	1615	Shared Neighborhood Hits	333
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

C1QR1_HUMAN
θ value	2.87452e-22 (rank : 86)	NC score	0.723881 (rank : 55)
Query Neighborhood Hits	905	Target Neighborhood Hits	493	Shared Neighborhood Hits	326
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	2.87452e-22 (rank : 87)	NC score	0.721367 (rank : 56)
Query Neighborhood Hits	905	Target Neighborhood Hits	342	Shared Neighborhood Hits	298
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CELR3_HUMAN
θ value	2.87452e-22 (rank : 88)	NC score	0.380515 (rank : 414)
Query Neighborhood Hits	905	Target Neighborhood Hits	680	Shared Neighborhood Hits	344
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

FBLN4_HUMAN
θ value	3.75424e-22 (rank : 89)	NC score	0.703278 (rank : 65)
Query Neighborhood Hits	905	Target Neighborhood Hits	278	Shared Neighborhood Hits	252
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

GAS6_MOUSE
θ value	3.75424e-22 (rank : 90)	NC score	0.708122 (rank : 62)
Query Neighborhood Hits	905	Target Neighborhood Hits	343	Shared Neighborhood Hits	316
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ANKK1_HUMAN
θ value	6.40375e-22 (rank : 91)	NC score	0.317128 (rank : 483)
Query Neighborhood Hits	905	Target Neighborhood Hits	1075	Shared Neighborhood Hits	313
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

CELR3_MOUSE
θ value	6.40375e-22 (rank : 92)	NC score	0.375825 (rank : 422)
Query Neighborhood Hits	905	Target Neighborhood Hits	687	Shared Neighborhood Hits	352
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

LAMA1_MOUSE
θ value	6.40375e-22 (rank : 93)	NC score	0.558856 (rank : 133)
Query Neighborhood Hits	905	Target Neighborhood Hits	838	Shared Neighborhood Hits	358
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB1_HUMAN
θ value	1.42661e-21 (rank : 94)	NC score	0.504481 (rank : 170)
Query Neighborhood Hits	905	Target Neighborhood Hits	1018	Shared Neighborhood Hits	338
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

STAB2_HUMAN
θ value	1.86321e-21 (rank : 95)	NC score	0.711896 (rank : 59)
Query Neighborhood Hits	905	Target Neighborhood Hits	534	Shared Neighborhood Hits	417
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

AGRIN_HUMAN
θ value	2.43343e-21 (rank : 96)	NC score	0.655592 (rank : 84)
Query Neighborhood Hits	905	Target Neighborhood Hits	582	Shared Neighborhood Hits	400
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

FBLN4_MOUSE
θ value	3.17815e-21 (rank : 97)	NC score	0.696774 (rank : 69)
Query Neighborhood Hits	905	Target Neighborhood Hits	270	Shared Neighborhood Hits	245
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

MATN2_MOUSE
θ value	4.15078e-21 (rank : 98)	NC score	0.629986 (rank : 96)
Query Neighborhood Hits	905	Target Neighborhood Hits	356	Shared Neighborhood Hits	272
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

STAB1_MOUSE
θ value	4.15078e-21 (rank : 99)	NC score	0.708827 (rank : 61)
Query Neighborhood Hits	905	Target Neighborhood Hits	566	Shared Neighborhood Hits	437
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

EDIL3_MOUSE
θ value	9.24701e-21 (rank : 100)	NC score	0.619416 (rank : 103)
Query Neighborhood Hits	905	Target Neighborhood Hits	317	Shared Neighborhood Hits	288
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

FBLN5_MOUSE
θ value	9.24701e-21 (rank : 101)	NC score	0.696237 (rank : 70)
Query Neighborhood Hits	905	Target Neighborhood Hits	317	Shared Neighborhood Hits	284
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

LAMB2_MOUSE
θ value	9.24701e-21 (rank : 102)	NC score	0.556796 (rank : 136)
Query Neighborhood Hits	905	Target Neighborhood Hits	722	Shared Neighborhood Hits	324
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

ANK1_MOUSE
θ value	1.2077e-20 (rank : 103)	NC score	0.481114 (rank : 205)
Query Neighborhood Hits	905	Target Neighborhood Hits	430	Shared Neighborhood Hits	294
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

EMR2_HUMAN
θ value	1.2077e-20 (rank : 104)	NC score	0.594158 (rank : 114)
Query Neighborhood Hits	905	Target Neighborhood Hits	345	Shared Neighborhood Hits	266
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

PGBM_HUMAN
θ value	1.2077e-20 (rank : 105)	NC score	0.425831 (rank : 356)
Query Neighborhood Hits	905	Target Neighborhood Hits	1113	Shared Neighborhood Hits	403
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

STAB1_HUMAN
θ value	1.2077e-20 (rank : 106)	NC score	0.710205 (rank : 60)
Query Neighborhood Hits	905	Target Neighborhood Hits	546	Shared Neighborhood Hits	414
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

ANKK1_MOUSE
θ value	1.5773e-20 (rank : 107)	NC score	0.308111 (rank : 486)
Query Neighborhood Hits	905	Target Neighborhood Hits	1072	Shared Neighborhood Hits	313
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANK1_HUMAN
θ value	2.69047e-20 (rank : 108)	NC score	0.479894 (rank : 210)
Query Neighborhood Hits	905	Target Neighborhood Hits	416	Shared Neighborhood Hits	297
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

LAMA1_HUMAN
θ value	2.69047e-20 (rank : 109)	NC score	0.556890 (rank : 135)
Query Neighborhood Hits	905	Target Neighborhood Hits	804	Shared Neighborhood Hits	349
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB2_HUMAN
θ value	2.69047e-20 (rank : 110)	NC score	0.562667 (rank : 132)
Query Neighborhood Hits	905	Target Neighborhood Hits	692	Shared Neighborhood Hits	335
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

PROS_HUMAN
θ value	2.69047e-20 (rank : 111)	NC score	0.700007 (rank : 68)
Query Neighborhood Hits	905	Target Neighborhood Hits	340	Shared Neighborhood Hits	319
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

GAS6_HUMAN
θ value	4.58923e-20 (rank : 112)	NC score	0.705270 (rank : 64)
Query Neighborhood Hits	905	Target Neighborhood Hits	348	Shared Neighborhood Hits	315
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

CD97_HUMAN
θ value	7.82807e-20 (rank : 113)	NC score	0.585931 (rank : 121)
Query Neighborhood Hits	905	Target Neighborhood Hits	353	Shared Neighborhood Hits	268
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

HABP2_MOUSE
θ value	1.02238e-19 (rank : 114)	NC score	0.350637 (rank : 451)
Query Neighborhood Hits	905	Target Neighborhood Hits	445	Shared Neighborhood Hits	282
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

PROS_MOUSE
θ value	1.33526e-19 (rank : 115)	NC score	0.696171 (rank : 71)
Query Neighborhood Hits	905	Target Neighborhood Hits	330	Shared Neighborhood Hits	305
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

EDIL3_HUMAN
θ value	1.74391e-19 (rank : 116)	NC score	0.610067 (rank : 109)
Query Neighborhood Hits	905	Target Neighborhood Hits	292	Shared Neighborhood Hits	266
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EHMT2_HUMAN
θ value	2.97466e-19 (rank : 117)	NC score	0.457029 (rank : 276)
Query Neighborhood Hits	905	Target Neighborhood Hits	498	Shared Neighborhood Hits	306
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANR28_MOUSE
θ value	6.62687e-19 (rank : 118)	NC score	0.484982 (rank : 197)
Query Neighborhood Hits	905	Target Neighborhood Hits	314	Shared Neighborhood Hits	295
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

NID1_MOUSE
θ value	1.13037e-18 (rank : 119)	NC score	0.643870 (rank : 92)
Query Neighborhood Hits	905	Target Neighborhood Hits	335	Shared Neighborhood Hits	272
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_MOUSE
θ value	1.13037e-18 (rank : 120)	NC score	0.649435 (rank : 88)
Query Neighborhood Hits	905	Target Neighborhood Hits	338	Shared Neighborhood Hits	284
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

TRBM_HUMAN
θ value	1.47631e-18 (rank : 121)	NC score	0.700156 (rank : 67)
Query Neighborhood Hits	905	Target Neighborhood Hits	339	Shared Neighborhood Hits	286
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

DAPK1_MOUSE
θ value	1.92812e-18 (rank : 122)	NC score	0.220609 (rank : 592)
Query Neighborhood Hits	905	Target Neighborhood Hits	1138	Shared Neighborhood Hits	312
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

CSPG2_HUMAN
θ value	2.5182e-18 (rank : 123)	NC score	0.498719 (rank : 176)
Query Neighborhood Hits	905	Target Neighborhood Hits	681	Shared Neighborhood Hits	288
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

ASB16_MOUSE
θ value	3.28887e-18 (rank : 124)	NC score	0.488775 (rank : 190)
Query Neighborhood Hits	905	Target Neighborhood Hits	306	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

CSPG2_MOUSE
θ value	3.28887e-18 (rank : 125)	NC score	0.503524 (rank : 172)
Query Neighborhood Hits	905	Target Neighborhood Hits	711	Shared Neighborhood Hits	299
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

EHMT2_MOUSE
θ value	3.28887e-18 (rank : 126)	NC score	0.447590 (rank : 306)
Query Neighborhood Hits	905	Target Neighborhood Hits	750	Shared Neighborhood Hits	314
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANR28_HUMAN
θ value	7.32683e-18 (rank : 127)	NC score	0.482707 (rank : 199)
Query Neighborhood Hits	905	Target Neighborhood Hits	314	Shared Neighborhood Hits	295
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR44_HUMAN
θ value	7.32683e-18 (rank : 128)	NC score	0.485684 (rank : 195)
Query Neighborhood Hits	905	Target Neighborhood Hits	318	Shared Neighborhood Hits	294
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

LAMC3_MOUSE
θ value	7.32683e-18 (rank : 129)	NC score	0.551429 (rank : 137)
Query Neighborhood Hits	905	Target Neighborhood Hits	624	Shared Neighborhood Hits	327
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

PGBM_MOUSE
θ value	7.32683e-18 (rank : 130)	NC score	0.431093 (rank : 345)
Query Neighborhood Hits	905	Target Neighborhood Hits	1073	Shared Neighborhood Hits	395
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

CELR1_MOUSE
θ value	9.56915e-18 (rank : 131)	NC score	0.365779 (rank : 437)
Query Neighborhood Hits	905	Target Neighborhood Hits	617	Shared Neighborhood Hits	326
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

HABP2_HUMAN
θ value	9.56915e-18 (rank : 132)	NC score	0.351317 (rank : 450)
Query Neighborhood Hits	905	Target Neighborhood Hits	431	Shared Neighborhood Hits	271
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LAMC3_HUMAN
θ value	9.56915e-18 (rank : 133)	NC score	0.544141 (rank : 139)
Query Neighborhood Hits	905	Target Neighborhood Hits	588	Shared Neighborhood Hits	329
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

CELR1_HUMAN
θ value	1.24977e-17 (rank : 134)	NC score	0.364439 (rank : 438)
Query Neighborhood Hits	905	Target Neighborhood Hits	613	Shared Neighborhood Hits	324
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

ANR50_HUMAN
θ value	1.63225e-17 (rank : 135)	NC score	0.494266 (rank : 184)
Query Neighborhood Hits	905	Target Neighborhood Hits	361	Shared Neighborhood Hits	295
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

WIF1_HUMAN
θ value	1.63225e-17 (rank : 136)	NC score	0.753108 (rank : 46)
Query Neighborhood Hits	905	Target Neighborhood Hits	392	Shared Neighborhood Hits	359
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	1.63225e-17 (rank : 137)	NC score	0.750698 (rank : 47)
Query Neighborhood Hits	905	Target Neighborhood Hits	393	Shared Neighborhood Hits	362
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CSPG3_MOUSE
θ value	2.13179e-17 (rank : 138)	NC score	0.492920 (rank : 185)
Query Neighborhood Hits	905	Target Neighborhood Hits	657	Shared Neighborhood Hits	291
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

NID1_HUMAN
θ value	2.13179e-17 (rank : 139)	NC score	0.643178 (rank : 93)
Query Neighborhood Hits	905	Target Neighborhood Hits	329	Shared Neighborhood Hits	282
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

ANKR6_HUMAN
θ value	2.7842e-17 (rank : 140)	NC score	0.499820 (rank : 174)
Query Neighborhood Hits	905	Target Neighborhood Hits	439	Shared Neighborhood Hits	293
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

CSPG3_HUMAN
θ value	2.7842e-17 (rank : 141)	NC score	0.485715 (rank : 194)
Query Neighborhood Hits	905	Target Neighborhood Hits	676	Shared Neighborhood Hits	275
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LAMC1_HUMAN
θ value	2.7842e-17 (rank : 142)	NC score	0.496802 (rank : 178)
Query Neighborhood Hits	905	Target Neighborhood Hits	922	Shared Neighborhood Hits	328
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

CSKI1_HUMAN
θ value	4.74913e-17 (rank : 143)	NC score	0.452894 (rank : 287)
Query Neighborhood Hits	905	Target Neighborhood Hits	997	Shared Neighborhood Hits	328
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NID2_HUMAN
θ value	4.74913e-17 (rank : 144)	NC score	0.651661 (rank : 85)
Query Neighborhood Hits	905	Target Neighborhood Hits	456	Shared Neighborhood Hits	291
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

UROM_HUMAN
θ value	4.74913e-17 (rank : 145)	NC score	0.658505 (rank : 82)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	259
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

CSKI1_MOUSE
θ value	6.20254e-17 (rank : 146)	NC score	0.455140 (rank : 281)
Query Neighborhood Hits	905	Target Neighborhood Hits	1031	Shared Neighborhood Hits	332
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DAPK1_HUMAN
θ value	6.20254e-17 (rank : 147)	NC score	0.215550 (rank : 600)
Query Neighborhood Hits	905	Target Neighborhood Hits	1130	Shared Neighborhood Hits	309
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

EGF_MOUSE
θ value	6.20254e-17 (rank : 148)	NC score	0.650078 (rank : 86)
Query Neighborhood Hits	905	Target Neighborhood Hits	358	Shared Neighborhood Hits	321
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

LAMC1_MOUSE
θ value	6.20254e-17 (rank : 149)	NC score	0.510116 (rank : 163)
Query Neighborhood Hits	905	Target Neighborhood Hits	856	Shared Neighborhood Hits	322
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

TSP4_MOUSE
θ value	8.10077e-17 (rank : 150)	NC score	0.632660 (rank : 95)
Query Neighborhood Hits	905	Target Neighborhood Hits	276	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

CELR2_HUMAN
θ value	1.058e-16 (rank : 151)	NC score	0.381470 (rank : 412)
Query Neighborhood Hits	905	Target Neighborhood Hits	657	Shared Neighborhood Hits	367
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

SSPO_MOUSE
θ value	1.058e-16 (rank : 152)	NC score	0.419275 (rank : 372)
Query Neighborhood Hits	905	Target Neighborhood Hits	800	Shared Neighborhood Hits	398
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ASB10_MOUSE
θ value	1.80466e-16 (rank : 153)	NC score	0.482596 (rank : 200)
Query Neighborhood Hits	905	Target Neighborhood Hits	301	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

PSD10_HUMAN
θ value	1.80466e-16 (rank : 154)	NC score	0.505055 (rank : 168)
Query Neighborhood Hits	905	Target Neighborhood Hits	301	Shared Neighborhood Hits	289
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

SHAN1_HUMAN
θ value	1.80466e-16 (rank : 155)	NC score	0.418388 (rank : 374)
Query Neighborhood Hits	905	Target Neighborhood Hits	1041	Shared Neighborhood Hits	298
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TRBM_MOUSE
θ value	3.07829e-16 (rank : 156)	NC score	0.686527 (rank : 73)
Query Neighborhood Hits	905	Target Neighborhood Hits	361	Shared Neighborhood Hits	292
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP4_HUMAN
θ value	4.02038e-16 (rank : 157)	NC score	0.629277 (rank : 97)
Query Neighborhood Hits	905	Target Neighborhood Hits	277	Shared Neighborhood Hits	255
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

EHMT1_HUMAN
θ value	6.85773e-16 (rank : 158)	NC score	0.453652 (rank : 284)
Query Neighborhood Hits	905	Target Neighborhood Hits	417	Shared Neighborhood Hits	290
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

CSKI2_HUMAN
θ value	8.95645e-16 (rank : 159)	NC score	0.444645 (rank : 319)
Query Neighborhood Hits	905	Target Neighborhood Hits	747	Shared Neighborhood Hits	316
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TRPA1_MOUSE
θ value	8.95645e-16 (rank : 160)	NC score	0.473270 (rank : 232)
Query Neighborhood Hits	905	Target Neighborhood Hits	343	Shared Neighborhood Hits	291
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ANR52_MOUSE
θ value	1.16975e-15 (rank : 161)	NC score	0.480620 (rank : 208)
Query Neighborhood Hits	905	Target Neighborhood Hits	318	Shared Neighborhood Hits	293
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR15_HUMAN
θ value	1.52774e-15 (rank : 162)	NC score	0.440423 (rank : 321)
Query Neighborhood Hits	905	Target Neighborhood Hits	478	Shared Neighborhood Hits	263
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

COMP_MOUSE
θ value	1.52774e-15 (rank : 163)	NC score	0.613419 (rank : 107)
Query Neighborhood Hits	905	Target Neighborhood Hits	290	Shared Neighborhood Hits	256
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

UROM_MOUSE
θ value	1.52774e-15 (rank : 164)	NC score	0.646956 (rank : 89)
Query Neighborhood Hits	905	Target Neighborhood Hits	276	Shared Neighborhood Hits	250
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ANR52_HUMAN
θ value	1.99529e-15 (rank : 165)	NC score	0.480014 (rank : 209)
Query Neighborhood Hits	905	Target Neighborhood Hits	322	Shared Neighborhood Hits	293
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

PSD10_MOUSE
θ value	1.99529e-15 (rank : 166)	NC score	0.503224 (rank : 173)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	287
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

TNKS2_HUMAN
θ value	2.60593e-15 (rank : 167)	NC score	0.478427 (rank : 213)
Query Neighborhood Hits	905	Target Neighborhood Hits	361	Shared Neighborhood Hits	294
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TSP3_MOUSE
θ value	2.60593e-15 (rank : 168)	NC score	0.576437 (rank : 127)
Query Neighborhood Hits	905	Target Neighborhood Hits	247	Shared Neighborhood Hits	222
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

CSKI2_MOUSE
θ value	3.40345e-15 (rank : 169)	NC score	0.445781 (rank : 314)
Query Neighborhood Hits	905	Target Neighborhood Hits	812	Shared Neighborhood Hits	309
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

FAT2_HUMAN
θ value	4.44505e-15 (rank : 170)	NC score	0.271245 (rank : 542)
Query Neighborhood Hits	905	Target Neighborhood Hits	507	Shared Neighborhood Hits	243
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

TNKS1_HUMAN
θ value	4.44505e-15 (rank : 171)	NC score	0.477122 (rank : 219)
Query Neighborhood Hits	905	Target Neighborhood Hits	477	Shared Neighborhood Hits	306
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

RIPK4_HUMAN
θ value	5.8054e-15 (rank : 172)	NC score	0.305463 (rank : 490)
Query Neighborhood Hits	905	Target Neighborhood Hits	1094	Shared Neighborhood Hits	317
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ASB2_HUMAN
θ value	9.90251e-15 (rank : 173)	NC score	0.481120 (rank : 204)
Query Neighborhood Hits	905	Target Neighborhood Hits	309	Shared Neighborhood Hits	283
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

CELR2_MOUSE
θ value	2.20605e-14 (rank : 174)	NC score	0.347501 (rank : 459)
Query Neighborhood Hits	905	Target Neighborhood Hits	584	Shared Neighborhood Hits	316
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

FRAS1_MOUSE
θ value	2.20605e-14 (rank : 175)	NC score	0.395937 (rank : 403)
Query Neighborhood Hits	905	Target Neighborhood Hits	747	Shared Neighborhood Hits	327
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MIB2_HUMAN
θ value	2.20605e-14 (rank : 176)	NC score	0.458452 (rank : 273)
Query Neighborhood Hits	905	Target Neighborhood Hits	438	Shared Neighborhood Hits	292
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ANFY1_MOUSE
θ value	3.76295e-14 (rank : 177)	NC score	0.440007 (rank : 323)
Query Neighborhood Hits	905	Target Neighborhood Hits	480	Shared Neighborhood Hits	292
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR23_HUMAN
θ value	4.91457e-14 (rank : 178)	NC score	0.492207 (rank : 186)
Query Neighborhood Hits	905	Target Neighborhood Hits	291	Shared Neighborhood Hits	284
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

BCL3_HUMAN
θ value	4.91457e-14 (rank : 179)	NC score	0.494403 (rank : 182)
Query Neighborhood Hits	905	Target Neighborhood Hits	324	Shared Neighborhood Hits	283
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

FRAS1_HUMAN
θ value	4.91457e-14 (rank : 180)	NC score	0.412610 (rank : 382)
Query Neighborhood Hits	905	Target Neighborhood Hits	759	Shared Neighborhood Hits	342
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

TSP1_MOUSE
θ value	4.91457e-14 (rank : 181)	NC score	0.458968 (rank : 270)
Query Neighborhood Hits	905	Target Neighborhood Hits	396	Shared Neighborhood Hits	275
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

CD97_MOUSE
θ value	6.41864e-14 (rank : 182)	NC score	0.509437 (rank : 165)
Query Neighborhood Hits	905	Target Neighborhood Hits	295	Shared Neighborhood Hits	221
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

LAMA3_MOUSE
θ value	6.41864e-14 (rank : 183)	NC score	0.486275 (rank : 193)
Query Neighborhood Hits	905	Target Neighborhood Hits	859	Shared Neighborhood Hits	351
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

ANFY1_HUMAN
θ value	8.38298e-14 (rank : 184)	NC score	0.439785 (rank : 325)
Query Neighborhood Hits	905	Target Neighborhood Hits	480	Shared Neighborhood Hits	291
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

TIE1_MOUSE
θ value	8.38298e-14 (rank : 185)	NC score	0.215382 (rank : 601)
Query Neighborhood Hits	905	Target Neighborhood Hits	1266	Shared Neighborhood Hits	325
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

MEGF8_MOUSE
θ value	1.09485e-13 (rank : 186)	NC score	0.644276 (rank : 91)
Query Neighborhood Hits	905	Target Neighborhood Hits	520	Shared Neighborhood Hits	353
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

RAI14_HUMAN
θ value	1.09485e-13 (rank : 187)	NC score	0.366913 (rank : 433)
Query Neighborhood Hits	905	Target Neighborhood Hits	1367	Shared Neighborhood Hits	316
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

TENR_MOUSE
θ value	1.09485e-13 (rank : 188)	NC score	0.428611 (rank : 349)
Query Neighborhood Hits	905	Target Neighborhood Hits	531	Shared Neighborhood Hits	320
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

ASB3_HUMAN
θ value	1.42992e-13 (rank : 189)	NC score	0.486525 (rank : 192)
Query Neighborhood Hits	905	Target Neighborhood Hits	316	Shared Neighborhood Hits	289
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

EGF_HUMAN
θ value	1.42992e-13 (rank : 190)	NC score	0.617274 (rank : 106)
Query Neighborhood Hits	905	Target Neighborhood Hits	343	Shared Neighborhood Hits	302
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

TIE1_HUMAN
θ value	1.42992e-13 (rank : 191)	NC score	0.218985 (rank : 594)
Query Neighborhood Hits	905	Target Neighborhood Hits	1241	Shared Neighborhood Hits	325
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

HGFA_HUMAN
θ value	1.86753e-13 (rank : 192)	NC score	0.272160 (rank : 539)
Query Neighborhood Hits	905	Target Neighborhood Hits	436	Shared Neighborhood Hits	243
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

TENR_HUMAN
θ value	1.86753e-13 (rank : 193)	NC score	0.421038 (rank : 367)
Query Neighborhood Hits	905	Target Neighborhood Hits	526	Shared Neighborhood Hits	312
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

USH2A_MOUSE
θ value	1.86753e-13 (rank : 194)	NC score	0.473175 (rank : 233)
Query Neighborhood Hits	905	Target Neighborhood Hits	626	Shared Neighborhood Hits	310
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

ASB2_MOUSE
θ value	2.43908e-13 (rank : 195)	NC score	0.477957 (rank : 217)
Query Neighborhood Hits	905	Target Neighborhood Hits	321	Shared Neighborhood Hits	281
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

HGFA_MOUSE
θ value	2.43908e-13 (rank : 196)	NC score	0.268651 (rank : 543)
Query Neighborhood Hits	905	Target Neighborhood Hits	419	Shared Neighborhood Hits	247
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ANR26_MOUSE
θ value	3.18553e-13 (rank : 197)	NC score	0.271491 (rank : 541)
Query Neighborhood Hits	905	Target Neighborhood Hits	1554	Shared Neighborhood Hits	312
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

TSP1_HUMAN
θ value	3.18553e-13 (rank : 198)	NC score	0.455652 (rank : 279)
Query Neighborhood Hits	905	Target Neighborhood Hits	389	Shared Neighborhood Hits	270
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

KR106_HUMAN
θ value	5.43371e-13 (rank : 199)	NC score	0.584509 (rank : 122)
Query Neighborhood Hits	905	Target Neighborhood Hits	347	Shared Neighborhood Hits	271
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

SUSD1_HUMAN
θ value	5.43371e-13 (rank : 200)	NC score	0.646389 (rank : 90)
Query Neighborhood Hits	905	Target Neighborhood Hits	285	Shared Neighborhood Hits	233
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TSP3_HUMAN
θ value	5.43371e-13 (rank : 201)	NC score	0.567941 (rank : 130)
Query Neighborhood Hits	905	Target Neighborhood Hits	250	Shared Neighborhood Hits	219
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

LAMC2_HUMAN
θ value	7.09661e-13 (rank : 202)	NC score	0.513679 (rank : 159)
Query Neighborhood Hits	905	Target Neighborhood Hits	715	Shared Neighborhood Hits	298
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LRP2_HUMAN
θ value	7.09661e-13 (rank : 203)	NC score	0.548891 (rank : 138)
Query Neighborhood Hits	905	Target Neighborhood Hits	573	Shared Neighborhood Hits	435
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

COMP_HUMAN
θ value	9.26847e-13 (rank : 204)	NC score	0.591114 (rank : 117)
Query Neighborhood Hits	905	Target Neighborhood Hits	258	Shared Neighborhood Hits	238
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

PCSK5_MOUSE
θ value	1.2105e-12 (rank : 205)	NC score	0.441606 (rank : 320)
Query Neighborhood Hits	905	Target Neighborhood Hits	613	Shared Neighborhood Hits	347
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

ASB10_HUMAN
θ value	1.58096e-12 (rank : 206)	NC score	0.478322 (rank : 214)
Query Neighborhood Hits	905	Target Neighborhood Hits	291	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

BCL3_MOUSE
θ value	1.58096e-12 (rank : 207)	NC score	0.489677 (rank : 187)
Query Neighborhood Hits	905	Target Neighborhood Hits	388	Shared Neighborhood Hits	290
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

LAMC2_MOUSE
θ value	1.58096e-12 (rank : 208)	NC score	0.532763 (rank : 143)
Query Neighborhood Hits	905	Target Neighborhood Hits	614	Shared Neighborhood Hits	299
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

MEGF8_HUMAN
θ value	1.58096e-12 (rank : 209)	NC score	0.649441 (rank : 87)
Query Neighborhood Hits	905	Target Neighborhood Hits	528	Shared Neighborhood Hits	359
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TRPA1_HUMAN
θ value	1.58096e-12 (rank : 210)	NC score	0.468803 (rank : 247)
Query Neighborhood Hits	905	Target Neighborhood Hits	339	Shared Neighborhood Hits	291
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

PA2G6_MOUSE
θ value	2.0648e-12 (rank : 211)	NC score	0.480716 (rank : 207)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

UACA_MOUSE
θ value	2.0648e-12 (rank : 212)	NC score	0.281703 (rank : 525)
Query Neighborhood Hits	905	Target Neighborhood Hits	1620	Shared Neighborhood Hits	308
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

KR107_HUMAN
θ value	2.69671e-12 (rank : 213)	NC score	0.589464 (rank : 118)
Query Neighborhood Hits	905	Target Neighborhood Hits	330	Shared Neighborhood Hits	264
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

GRN_MOUSE
θ value	3.52202e-12 (rank : 214)	NC score	0.517569 (rank : 157)
Query Neighborhood Hits	905	Target Neighborhood Hits	248	Shared Neighborhood Hits	214
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

RAI14_MOUSE
θ value	3.52202e-12 (rank : 215)	NC score	0.341591 (rank : 467)
Query Neighborhood Hits	905	Target Neighborhood Hits	1505	Shared Neighborhood Hits	318
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANR12_HUMAN
θ value	4.59992e-12 (rank : 216)	NC score	0.394353 (rank : 405)
Query Neighborhood Hits	905	Target Neighborhood Hits	1081	Shared Neighborhood Hits	286
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR29_HUMAN
θ value	4.59992e-12 (rank : 217)	NC score	0.495636 (rank : 180)
Query Neighborhood Hits	905	Target Neighborhood Hits	294	Shared Neighborhood Hits	282
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

EGFL7_MOUSE
θ value	4.59992e-12 (rank : 218)	NC score	0.679095 (rank : 79)
Query Neighborhood Hits	905	Target Neighborhood Hits	287	Shared Neighborhood Hits	270
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

KR104_HUMAN
θ value	4.59992e-12 (rank : 219)	NC score	0.581801 (rank : 124)
Query Neighborhood Hits	905	Target Neighborhood Hits	313	Shared Neighborhood Hits	249
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

ANR23_MOUSE
θ value	6.00763e-12 (rank : 220)	NC score	0.485523 (rank : 196)
Query Neighborhood Hits	905	Target Neighborhood Hits	296	Shared Neighborhood Hits	283
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR35_HUMAN
θ value	6.00763e-12 (rank : 221)	NC score	0.452172 (rank : 293)
Query Neighborhood Hits	905	Target Neighborhood Hits	784	Shared Neighborhood Hits	306
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASB3_MOUSE
θ value	6.00763e-12 (rank : 222)	NC score	0.481493 (rank : 203)
Query Neighborhood Hits	905	Target Neighborhood Hits	316	Shared Neighborhood Hits	288
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

EGFL7_HUMAN
θ value	6.00763e-12 (rank : 223)	NC score	0.686093 (rank : 74)
Query Neighborhood Hits	905	Target Neighborhood Hits	325	Shared Neighborhood Hits	296
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

MYPT2_HUMAN
θ value	6.00763e-12 (rank : 224)	NC score	0.456819 (rank : 278)
Query Neighborhood Hits	905	Target Neighborhood Hits	707	Shared Neighborhood Hits	293
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ASB8_HUMAN
θ value	7.84624e-12 (rank : 225)	NC score	0.489444 (rank : 188)
Query Neighborhood Hits	905	Target Neighborhood Hits	294	Shared Neighborhood Hits	283
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
θ value	7.84624e-12 (rank : 226)	NC score	0.489025 (rank : 189)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	280
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

GABP2_HUMAN
θ value	7.84624e-12 (rank : 227)	NC score	0.481021 (rank : 206)
Query Neighborhood Hits	905	Target Neighborhood Hits	454	Shared Neighborhood Hits	281
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP2_MOUSE
θ value	7.84624e-12 (rank : 228)	NC score	0.481831 (rank : 202)
Query Neighborhood Hits	905	Target Neighborhood Hits	429	Shared Neighborhood Hits	281
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ASB16_HUMAN
θ value	1.02475e-11 (rank : 229)	NC score	0.472373 (rank : 236)
Query Neighborhood Hits	905	Target Neighborhood Hits	286	Shared Neighborhood Hits	272
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

NFKB1_MOUSE
θ value	1.02475e-11 (rank : 230)	NC score	0.416405 (rank : 376)
Query Neighborhood Hits	905	Target Neighborhood Hits	300	Shared Neighborhood Hits	271
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

IKBE_HUMAN
θ value	1.33837e-11 (rank : 231)	NC score	0.467410 (rank : 251)
Query Neighborhood Hits	905	Target Neighborhood Hits	288	Shared Neighborhood Hits	268
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

INVS_HUMAN
θ value	1.33837e-11 (rank : 232)	NC score	0.477985 (rank : 216)
Query Neighborhood Hits	905	Target Neighborhood Hits	455	Shared Neighborhood Hits	290
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

UACA_HUMAN
θ value	1.33837e-11 (rank : 233)	NC score	0.293468 (rank : 506)
Query Neighborhood Hits	905	Target Neighborhood Hits	1622	Shared Neighborhood Hits	312
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ZDH17_HUMAN
θ value	1.33837e-11 (rank : 234)	NC score	0.423003 (rank : 362)
Query Neighborhood Hits	905	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANKS1_HUMAN
θ value	1.74796e-11 (rank : 235)	NC score	0.461412 (rank : 268)
Query Neighborhood Hits	905	Target Neighborhood Hits	438	Shared Neighborhood Hits	297
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

MYPT1_HUMAN
θ value	1.74796e-11 (rank : 236)	NC score	0.452279 (rank : 292)
Query Neighborhood Hits	905	Target Neighborhood Hits	723	Shared Neighborhood Hits	294
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

INVS_MOUSE
θ value	2.28291e-11 (rank : 237)	NC score	0.473579 (rank : 228)
Query Neighborhood Hits	905	Target Neighborhood Hits	609	Shared Neighborhood Hits	297
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MIB2_MOUSE
θ value	2.28291e-11 (rank : 238)	NC score	0.448738 (rank : 300)
Query Neighborhood Hits	905	Target Neighborhood Hits	409	Shared Neighborhood Hits	284
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

MIB1_HUMAN
θ value	2.98157e-11 (rank : 239)	NC score	0.458458 (rank : 272)
Query Neighborhood Hits	905	Target Neighborhood Hits	470	Shared Neighborhood Hits	297
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	2.98157e-11 (rank : 240)	NC score	0.457633 (rank : 274)
Query Neighborhood Hits	905	Target Neighborhood Hits	471	Shared Neighborhood Hits	296
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ANKS3_MOUSE
θ value	3.89403e-11 (rank : 241)	NC score	0.466831 (rank : 252)
Query Neighborhood Hits	905	Target Neighborhood Hits	355	Shared Neighborhood Hits	273
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

CTTB2_HUMAN
θ value	3.89403e-11 (rank : 242)	NC score	0.403841 (rank : 395)
Query Neighborhood Hits	905	Target Neighborhood Hits	1061	Shared Neighborhood Hits	295
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ELTD1_MOUSE
θ value	3.89403e-11 (rank : 243)	NC score	0.495726 (rank : 179)
Query Neighborhood Hits	905	Target Neighborhood Hits	288	Shared Neighborhood Hits	215
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

FA12_HUMAN
θ value	3.89403e-11 (rank : 244)	NC score	0.249480 (rank : 564)
Query Neighborhood Hits	905	Target Neighborhood Hits	425	Shared Neighborhood Hits	239
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

TENN_HUMAN
θ value	3.89403e-11 (rank : 245)	NC score	0.345875 (rank : 462)
Query Neighborhood Hits	905	Target Neighborhood Hits	453	Shared Neighborhood Hits	277
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

ZDH17_MOUSE
θ value	3.89403e-11 (rank : 246)	NC score	0.419418 (rank : 371)
Query Neighborhood Hits	905	Target Neighborhood Hits	328	Shared Neighborhood Hits	276
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANR42_MOUSE
θ value	5.08577e-11 (rank : 247)	NC score	0.470097 (rank : 243)
Query Neighborhood Hits	905	Target Neighborhood Hits	334	Shared Neighborhood Hits	282
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB15_HUMAN
θ value	5.08577e-11 (rank : 248)	NC score	0.462297 (rank : 266)
Query Neighborhood Hits	905	Target Neighborhood Hits	305	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

RN5A_MOUSE
θ value	5.08577e-11 (rank : 249)	NC score	0.427790 (rank : 352)
Query Neighborhood Hits	905	Target Neighborhood Hits	899	Shared Neighborhood Hits	301
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

TNI3K_HUMAN
θ value	5.08577e-11 (rank : 250)	NC score	0.239779 (rank : 573)
Query Neighborhood Hits	905	Target Neighborhood Hits	1084	Shared Neighborhood Hits	316
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANR18_HUMAN
θ value	6.64225e-11 (rank : 251)	NC score	0.356104 (rank : 446)
Query Neighborhood Hits	905	Target Neighborhood Hits	1106	Shared Neighborhood Hits	288
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ASZ1_MOUSE
θ value	6.64225e-11 (rank : 252)	NC score	0.472537 (rank : 235)
Query Neighborhood Hits	905	Target Neighborhood Hits	319	Shared Neighborhood Hits	275
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

MYPT1_MOUSE
θ value	6.64225e-11 (rank : 253)	NC score	0.462886 (rank : 263)
Query Neighborhood Hits	905	Target Neighborhood Hits	539	Shared Neighborhood Hits	290
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ANR19_HUMAN
θ value	8.67504e-11 (rank : 254)	NC score	0.445873 (rank : 312)
Query Neighborhood Hits	905	Target Neighborhood Hits	276	Shared Neighborhood Hits	267
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

GRN_HUMAN
θ value	1.133e-10 (rank : 255)	NC score	0.509782 (rank : 164)
Query Neighborhood Hits	905	Target Neighborhood Hits	268	Shared Neighborhood Hits	222
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

IKBA_MOUSE
θ value	1.133e-10 (rank : 256)	NC score	0.469287 (rank : 244)
Query Neighborhood Hits	905	Target Neighborhood Hits	283	Shared Neighborhood Hits	276
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

POTE8_HUMAN
θ value	1.133e-10 (rank : 257)	NC score	0.440246 (rank : 322)
Query Neighborhood Hits	905	Target Neighborhood Hits	337	Shared Neighborhood Hits	282
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

TSP2_HUMAN
θ value	1.133e-10 (rank : 258)	NC score	0.417784 (rank : 375)
Query Neighborhood Hits	905	Target Neighborhood Hits	359	Shared Neighborhood Hits	257
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ANKR2_MOUSE
θ value	1.47974e-10 (rank : 259)	NC score	0.476321 (rank : 222)
Query Neighborhood Hits	905	Target Neighborhood Hits	312	Shared Neighborhood Hits	286
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKS3_HUMAN
θ value	1.47974e-10 (rank : 260)	NC score	0.467870 (rank : 249)
Query Neighborhood Hits	905	Target Neighborhood Hits	355	Shared Neighborhood Hits	272
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

IKBA_HUMAN
θ value	1.47974e-10 (rank : 261)	NC score	0.475769 (rank : 224)
Query Neighborhood Hits	905	Target Neighborhood Hits	280	Shared Neighborhood Hits	275
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ANKR1_HUMAN
θ value	1.9326e-10 (rank : 262)	NC score	0.478028 (rank : 215)
Query Neighborhood Hits	905	Target Neighborhood Hits	308	Shared Neighborhood Hits	278
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR1_MOUSE
θ value	1.9326e-10 (rank : 263)	NC score	0.476205 (rank : 223)
Query Neighborhood Hits	905	Target Neighborhood Hits	316	Shared Neighborhood Hits	284
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

IKBE_MOUSE
θ value	1.9326e-10 (rank : 264)	NC score	0.470618 (rank : 242)
Query Neighborhood Hits	905	Target Neighborhood Hits	308	Shared Neighborhood Hits	280
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ITB6_HUMAN
θ value	1.9326e-10 (rank : 265)	NC score	0.471027 (rank : 241)
Query Neighborhood Hits	905	Target Neighborhood Hits	318	Shared Neighborhood Hits	270
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

LDLR_HUMAN
θ value	1.9326e-10 (rank : 266)	NC score	0.537804 (rank : 140)
Query Neighborhood Hits	905	Target Neighborhood Hits	375	Shared Neighborhood Hits	313
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

PA2G6_HUMAN
θ value	1.9326e-10 (rank : 267)	NC score	0.478694 (rank : 212)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	278
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PP16A_HUMAN
θ value	1.9326e-10 (rank : 268)	NC score	0.458557 (rank : 271)
Query Neighborhood Hits	905	Target Neighborhood Hits	340	Shared Neighborhood Hits	278
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

GABP3_MOUSE
θ value	2.52405e-10 (rank : 269)	NC score	0.482366 (rank : 201)
Query Neighborhood Hits	905	Target Neighborhood Hits	330	Shared Neighborhood Hits	276
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

MFGM_MOUSE
θ value	2.52405e-10 (rank : 270)	NC score	0.445623 (rank : 316)
Query Neighborhood Hits	905	Target Neighborhood Hits	233	Shared Neighborhood Hits	207
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

ZDH13_HUMAN
θ value	2.52405e-10 (rank : 271)	NC score	0.424461 (rank : 358)
Query Neighborhood Hits	905	Target Neighborhood Hits	322	Shared Neighborhood Hits	276
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ANR49_MOUSE
θ value	3.29651e-10 (rank : 272)	NC score	0.474377 (rank : 225)
Query Neighborhood Hits	905	Target Neighborhood Hits	285	Shared Neighborhood Hits	273
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ASB15_MOUSE
θ value	3.29651e-10 (rank : 273)	NC score	0.453550 (rank : 285)
Query Neighborhood Hits	905	Target Neighborhood Hits	292	Shared Neighborhood Hits	271
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ITB6_MOUSE
θ value	3.29651e-10 (rank : 274)	NC score	0.487708 (rank : 191)
Query Neighborhood Hits	905	Target Neighborhood Hits	341	Shared Neighborhood Hits	283
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

TNI3K_MOUSE
θ value	3.29651e-10 (rank : 275)	NC score	0.235937 (rank : 582)
Query Neighborhood Hits	905	Target Neighborhood Hits	1079	Shared Neighborhood Hits	315
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

USH2A_HUMAN
θ value	3.29651e-10 (rank : 276)	NC score	0.448252 (rank : 303)
Query Neighborhood Hits	905	Target Neighborhood Hits	600	Shared Neighborhood Hits	284
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

OSBL1_HUMAN
θ value	4.30538e-10 (rank : 277)	NC score	0.375414 (rank : 423)
Query Neighborhood Hits	905	Target Neighborhood Hits	368	Shared Neighborhood Hits	281
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANKR7_HUMAN
θ value	5.62301e-10 (rank : 278)	NC score	0.464864 (rank : 258)
Query Neighborhood Hits	905	Target Neighborhood Hits	286	Shared Neighborhood Hits	273
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANR49_HUMAN
θ value	5.62301e-10 (rank : 279)	NC score	0.474249 (rank : 226)
Query Neighborhood Hits	905	Target Neighborhood Hits	282	Shared Neighborhood Hits	272
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

EGFL8_HUMAN
θ value	5.62301e-10 (rank : 280)	NC score	0.656051 (rank : 83)
Query Neighborhood Hits	905	Target Neighborhood Hits	270	Shared Neighborhood Hits	252
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

NFKB2_HUMAN
θ value	5.62301e-10 (rank : 281)	NC score	0.413135 (rank : 381)
Query Neighborhood Hits	905	Target Neighborhood Hits	325	Shared Neighborhood Hits	282
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

POT15_HUMAN
θ value	5.62301e-10 (rank : 282)	NC score	0.410893 (rank : 386)
Query Neighborhood Hits	905	Target Neighborhood Hits	893	Shared Neighborhood Hits	286
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

PP16A_MOUSE
θ value	5.62301e-10 (rank : 283)	NC score	0.465983 (rank : 254)
Query Neighborhood Hits	905	Target Neighborhood Hits	318	Shared Neighborhood Hits	284
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

TENN_MOUSE
θ value	5.62301e-10 (rank : 284)	NC score	0.363270 (rank : 440)
Query Neighborhood Hits	905	Target Neighborhood Hits	484	Shared Neighborhood Hits	282
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

ANR10_MOUSE
θ value	7.34386e-10 (rank : 285)	NC score	0.445040 (rank : 317)
Query Neighborhood Hits	905	Target Neighborhood Hits	273	Shared Neighborhood Hits	268
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR47_HUMAN
θ value	7.34386e-10 (rank : 286)	NC score	0.423087 (rank : 360)
Query Neighborhood Hits	905	Target Neighborhood Hits	369	Shared Neighborhood Hits	254
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASB13_HUMAN
θ value	7.34386e-10 (rank : 287)	NC score	0.461777 (rank : 267)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	283
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB7_HUMAN
θ value	7.34386e-10 (rank : 288)	NC score	0.473628 (rank : 227)
Query Neighborhood Hits	905	Target Neighborhood Hits	296	Shared Neighborhood Hits	280
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	7.34386e-10 (rank : 289)	NC score	0.473574 (rank : 229)
Query Neighborhood Hits	905	Target Neighborhood Hits	296	Shared Neighborhood Hits	280
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ITB4_HUMAN
θ value	7.34386e-10 (rank : 290)	NC score	0.422995 (rank : 363)
Query Neighborhood Hits	905	Target Neighborhood Hits	458	Shared Neighborhood Hits	267
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

LRP4_MOUSE
θ value	7.34386e-10 (rank : 291)	NC score	0.477119 (rank : 220)
Query Neighborhood Hits	905	Target Neighborhood Hits	351	Shared Neighborhood Hits	286
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

MATN4_HUMAN
θ value	7.34386e-10 (rank : 292)	NC score	0.522878 (rank : 150)
Query Neighborhood Hits	905	Target Neighborhood Hits	287	Shared Neighborhood Hits	239
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

NFKB1_HUMAN
θ value	7.34386e-10 (rank : 293)	NC score	0.416250 (rank : 377)
Query Neighborhood Hits	905	Target Neighborhood Hits	306	Shared Neighborhood Hits	276
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

OSBL1_MOUSE
θ value	7.34386e-10 (rank : 294)	NC score	0.366863 (rank : 434)
Query Neighborhood Hits	905	Target Neighborhood Hits	336	Shared Neighborhood Hits	281
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ZDH13_MOUSE
θ value	7.34386e-10 (rank : 295)	NC score	0.419780 (rank : 370)
Query Neighborhood Hits	905	Target Neighborhood Hits	329	Shared Neighborhood Hits	279
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANKR2_HUMAN
θ value	9.59137e-10 (rank : 296)	NC score	0.472613 (rank : 234)
Query Neighborhood Hits	905	Target Neighborhood Hits	321	Shared Neighborhood Hits	287
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR21_HUMAN
θ value	9.59137e-10 (rank : 297)	NC score	0.411894 (rank : 384)
Query Neighborhood Hits	905	Target Neighborhood Hits	864	Shared Neighborhood Hits	284
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ASB13_MOUSE
θ value	9.59137e-10 (rank : 298)	NC score	0.462884 (rank : 264)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

FA7_HUMAN
θ value	9.59137e-10 (rank : 299)	NC score	0.273580 (rank : 538)
Query Neighborhood Hits	905	Target Neighborhood Hits	404	Shared Neighborhood Hits	246
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FANK1_HUMAN
θ value	9.59137e-10 (rank : 300)	NC score	0.479682 (rank : 211)
Query Neighborhood Hits	905	Target Neighborhood Hits	326	Shared Neighborhood Hits	285
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

LRP8_MOUSE
θ value	9.59137e-10 (rank : 301)	NC score	0.521780 (rank : 154)
Query Neighborhood Hits	905	Target Neighborhood Hits	385	Shared Neighborhood Hits	302
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

VWF_MOUSE
θ value	9.59137e-10 (rank : 302)	NC score	0.284495 (rank : 521)
Query Neighborhood Hits	905	Target Neighborhood Hits	381	Shared Neighborhood Hits	235
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

A20A1_HUMAN
θ value	1.25267e-09 (rank : 303)	NC score	0.379444 (rank : 416)
Query Neighborhood Hits	905	Target Neighborhood Hits	698	Shared Neighborhood Hits	276
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
θ value	1.25267e-09 (rank : 304)	NC score	0.378894 (rank : 419)
Query Neighborhood Hits	905	Target Neighborhood Hits	716	Shared Neighborhood Hits	279
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A3_HUMAN
θ value	1.25267e-09 (rank : 305)	NC score	0.380737 (rank : 413)
Query Neighborhood Hits	905	Target Neighborhood Hits	692	Shared Neighborhood Hits	280
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	1.25267e-09 (rank : 306)	NC score	0.378140 (rank : 420)
Query Neighborhood Hits	905	Target Neighborhood Hits	710	Shared Neighborhood Hits	280
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANKS1_MOUSE
θ value	1.25267e-09 (rank : 307)	NC score	0.450029 (rank : 297)
Query Neighborhood Hits	905	Target Neighborhood Hits	453	Shared Neighborhood Hits	298
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANR11_HUMAN
θ value	1.25267e-09 (rank : 308)	NC score	0.405218 (rank : 394)
Query Neighborhood Hits	905	Target Neighborhood Hits	1289	Shared Neighborhood Hits	296
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

EGFL8_MOUSE
θ value	1.25267e-09 (rank : 309)	NC score	0.660236 (rank : 81)
Query Neighborhood Hits	905	Target Neighborhood Hits	266	Shared Neighborhood Hits	256
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

LAMB3_MOUSE
θ value	1.25267e-09 (rank : 310)	NC score	0.499671 (rank : 175)
Query Neighborhood Hits	905	Target Neighborhood Hits	444	Shared Neighborhood Hits	254
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

AN36B_HUMAN
θ value	1.63604e-09 (rank : 311)	NC score	0.464756 (rank : 259)
Query Neighborhood Hits	905	Target Neighborhood Hits	294	Shared Neighborhood Hits	274
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANR16_HUMAN
θ value	1.63604e-09 (rank : 312)	NC score	0.484338 (rank : 198)
Query Neighborhood Hits	905	Target Neighborhood Hits	286	Shared Neighborhood Hits	278
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR38_MOUSE
θ value	1.63604e-09 (rank : 313)	NC score	0.399471 (rank : 399)
Query Neighborhood Hits	905	Target Neighborhood Hits	512	Shared Neighborhood Hits	235
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

LRP4_HUMAN
θ value	1.63604e-09 (rank : 314)	NC score	0.473477 (rank : 231)
Query Neighborhood Hits	905	Target Neighborhood Hits	355	Shared Neighborhood Hits	288
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

TIE2_MOUSE
θ value	1.63604e-09 (rank : 315)	NC score	0.189463 (rank : 645)
Query Neighborhood Hits	905	Target Neighborhood Hits	1204	Shared Neighborhood Hits	301
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

ASZ1_HUMAN
θ value	2.13673e-09 (rank : 316)	NC score	0.467570 (rank : 250)
Query Neighborhood Hits	905	Target Neighborhood Hits	341	Shared Neighborhood Hits	274
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

LAMB3_HUMAN
θ value	2.13673e-09 (rank : 317)	NC score	0.468880 (rank : 245)
Query Neighborhood Hits	905	Target Neighborhood Hits	461	Shared Neighborhood Hits	227
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

RN5A_HUMAN
θ value	2.13673e-09 (rank : 318)	NC score	0.456918 (rank : 277)
Query Neighborhood Hits	905	Target Neighborhood Hits	608	Shared Neighborhood Hits	281
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASB5_HUMAN
θ value	2.79066e-09 (rank : 319)	NC score	0.437619 (rank : 328)
Query Neighborhood Hits	905	Target Neighborhood Hits	283	Shared Neighborhood Hits	268
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

LRP8_HUMAN
θ value	2.79066e-09 (rank : 320)	NC score	0.503755 (rank : 171)
Query Neighborhood Hits	905	Target Neighborhood Hits	346	Shared Neighborhood Hits	274
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

FANK1_MOUSE
θ value	3.64472e-09 (rank : 321)	NC score	0.473549 (rank : 230)
Query Neighborhood Hits	905	Target Neighborhood Hits	325	Shared Neighborhood Hits	284
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

IKBB_MOUSE
θ value	3.64472e-09 (rank : 322)	NC score	0.449014 (rank : 299)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ITB2_HUMAN
θ value	3.64472e-09 (rank : 323)	NC score	0.427308 (rank : 355)
Query Neighborhood Hits	905	Target Neighborhood Hits	282	Shared Neighborhood Hits	241
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

TIE2_HUMAN
θ value	3.64472e-09 (rank : 324)	NC score	0.190322 (rank : 639)
Query Neighborhood Hits	905	Target Neighborhood Hits	1192	Shared Neighborhood Hits	296
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

ASB5_MOUSE
θ value	4.76016e-09 (rank : 325)	NC score	0.435087 (rank : 334)
Query Neighborhood Hits	905	Target Neighborhood Hits	266	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANR10_HUMAN
θ value	6.21693e-09 (rank : 326)	NC score	0.446426 (rank : 309)
Query Neighborhood Hits	905	Target Neighborhood Hits	289	Shared Neighborhood Hits	270
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

LAMA4_MOUSE
θ value	8.11959e-09 (rank : 327)	NC score	0.434505 (rank : 335)
Query Neighborhood Hits	905	Target Neighborhood Hits	584	Shared Neighborhood Hits	237
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

VLDLR_HUMAN
θ value	8.11959e-09 (rank : 328)	NC score	0.529613 (rank : 145)
Query Neighborhood Hits	905	Target Neighborhood Hits	383	Shared Neighborhood Hits	306
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ANR38_HUMAN
θ value	1.06045e-08 (rank : 329)	NC score	0.409563 (rank : 389)
Query Neighborhood Hits	905	Target Neighborhood Hits	443	Shared Neighborhood Hits	243
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CREL1_HUMAN
θ value	1.38499e-08 (rank : 330)	NC score	0.679222 (rank : 78)
Query Neighborhood Hits	905	Target Neighborhood Hits	441	Shared Neighborhood Hits	291
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LAMA4_HUMAN
θ value	1.38499e-08 (rank : 331)	NC score	0.412023 (rank : 383)
Query Neighborhood Hits	905	Target Neighborhood Hits	708	Shared Neighborhood Hits	244
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MEGF9_MOUSE
θ value	1.38499e-08 (rank : 332)	NC score	0.535836 (rank : 141)
Query Neighborhood Hits	905	Target Neighborhood Hits	896	Shared Neighborhood Hits	288
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

TSP2_MOUSE
θ value	1.38499e-08 (rank : 333)	NC score	0.410642 (rank : 388)
Query Neighborhood Hits	905	Target Neighborhood Hits	352	Shared Neighborhood Hits	249
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ACBD6_HUMAN
θ value	1.80886e-08 (rank : 334)	NC score	0.445847 (rank : 313)
Query Neighborhood Hits	905	Target Neighborhood Hits	304	Shared Neighborhood Hits	279
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANKR5_MOUSE
θ value	2.36244e-08 (rank : 335)	NC score	0.452881 (rank : 288)
Query Neighborhood Hits	905	Target Neighborhood Hits	298	Shared Neighborhood Hits	281
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB9_HUMAN
θ value	2.36244e-08 (rank : 336)	NC score	0.429399 (rank : 347)
Query Neighborhood Hits	905	Target Neighborhood Hits	267	Shared Neighborhood Hits	253
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

CRIM1_HUMAN
θ value	2.36244e-08 (rank : 337)	NC score	0.462747 (rank : 265)
Query Neighborhood Hits	905	Target Neighborhood Hits	362	Shared Neighborhood Hits	251
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

LDLR_MOUSE
θ value	2.36244e-08 (rank : 338)	NC score	0.513035 (rank : 160)
Query Neighborhood Hits	905	Target Neighborhood Hits	382	Shared Neighborhood Hits	310
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

ACBD6_MOUSE
θ value	3.08544e-08 (rank : 339)	NC score	0.447691 (rank : 305)
Query Neighborhood Hits	905	Target Neighborhood Hits	305	Shared Neighborhood Hits	280
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR47_MOUSE
θ value	3.08544e-08 (rank : 340)	NC score	0.432908 (rank : 339)
Query Neighborhood Hits	905	Target Neighborhood Hits	350	Shared Neighborhood Hits	260
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

VLDLR_MOUSE
θ value	3.08544e-08 (rank : 341)	NC score	0.527442 (rank : 147)
Query Neighborhood Hits	905	Target Neighborhood Hits	360	Shared Neighborhood Hits	295
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ADA33_MOUSE
θ value	4.0297e-08 (rank : 342)	NC score	0.156566 (rank : 689)
Query Neighborhood Hits	905	Target Neighborhood Hits	231	Shared Neighborhood Hits	174
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ANKS6_MOUSE
θ value	4.0297e-08 (rank : 343)	NC score	0.455594 (rank : 280)
Query Neighborhood Hits	905	Target Neighborhood Hits	435	Shared Neighborhood Hits	289
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

CD2A1_MOUSE
θ value	5.26297e-08 (rank : 344)	NC score	0.427312 (rank : 354)
Query Neighborhood Hits	905	Target Neighborhood Hits	206	Shared Neighborhood Hits	202
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

FA10_MOUSE
θ value	5.26297e-08 (rank : 345)	NC score	0.300985 (rank : 497)
Query Neighborhood Hits	905	Target Neighborhood Hits	435	Shared Neighborhood Hits	275
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

HECD1_HUMAN
θ value	5.26297e-08 (rank : 346)	NC score	0.358402 (rank : 444)
Query Neighborhood Hits	905	Target Neighborhood Hits	371	Shared Neighborhood Hits	273
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ILK1_HUMAN
θ value	5.26297e-08 (rank : 347)	NC score	0.281063 (rank : 526)
Query Neighborhood Hits	905	Target Neighborhood Hits	857	Shared Neighborhood Hits	300
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	5.26297e-08 (rank : 348)	NC score	0.291026 (rank : 508)
Query Neighborhood Hits	905	Target Neighborhood Hits	848	Shared Neighborhood Hits	300
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

KR101_HUMAN
θ value	5.26297e-08 (rank : 349)	NC score	0.507357 (rank : 166)
Query Neighborhood Hits	905	Target Neighborhood Hits	261	Shared Neighborhood Hits	203
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

MATN4_MOUSE
θ value	5.26297e-08 (rank : 350)	NC score	0.494304 (rank : 183)
Query Neighborhood Hits	905	Target Neighborhood Hits	277	Shared Neighborhood Hits	229
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MUC5B_HUMAN
θ value	5.26297e-08 (rank : 351)	NC score	0.316753 (rank : 484)
Query Neighborhood Hits	905	Target Neighborhood Hits	1020	Shared Neighborhood Hits	322
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PROZ_MOUSE
θ value	5.26297e-08 (rank : 352)	NC score	0.515702 (rank : 158)
Query Neighborhood Hits	905	Target Neighborhood Hits	410	Shared Neighborhood Hits	268
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FA10_HUMAN
θ value	6.87365e-08 (rank : 353)	NC score	0.295928 (rank : 503)
Query Neighborhood Hits	905	Target Neighborhood Hits	431	Shared Neighborhood Hits	268
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

SORL_MOUSE
θ value	6.87365e-08 (rank : 354)	NC score	0.371620 (rank : 427)
Query Neighborhood Hits	905	Target Neighborhood Hits	439	Shared Neighborhood Hits	254
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

ANKS6_HUMAN
θ value	8.97725e-08 (rank : 355)	NC score	0.452632 (rank : 290)
Query Neighborhood Hits	905	Target Neighborhood Hits	411	Shared Neighborhood Hits	286
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR39_HUMAN
θ value	8.97725e-08 (rank : 356)	NC score	0.471442 (rank : 238)
Query Neighborhood Hits	905	Target Neighborhood Hits	285	Shared Neighborhood Hits	279
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ELTD1_HUMAN
θ value	8.97725e-08 (rank : 357)	NC score	0.378101 (rank : 421)
Query Neighborhood Hits	905	Target Neighborhood Hits	269	Shared Neighborhood Hits	189
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ILK_MOUSE
θ value	1.17247e-07 (rank : 358)	NC score	0.279692 (rank : 529)
Query Neighborhood Hits	905	Target Neighborhood Hits	858	Shared Neighborhood Hits	300
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ITB5_MOUSE
θ value	1.17247e-07 (rank : 359)	NC score	0.467956 (rank : 248)
Query Neighborhood Hits	905	Target Neighborhood Hits	329	Shared Neighborhood Hits	283
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

PP16B_HUMAN
θ value	1.17247e-07 (rank : 360)	NC score	0.453176 (rank : 286)
Query Neighborhood Hits	905	Target Neighborhood Hits	307	Shared Neighborhood Hits	280
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

PROZ_HUMAN
θ value	1.17247e-07 (rank : 361)	NC score	0.511447 (rank : 161)
Query Neighborhood Hits	905	Target Neighborhood Hits	422	Shared Neighborhood Hits	276
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

ASB4_MOUSE
θ value	1.53129e-07 (rank : 362)	NC score	0.448206 (rank : 304)
Query Neighborhood Hits	905	Target Neighborhood Hits	265	Shared Neighborhood Hits	258
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

CDN2D_HUMAN
θ value	1.53129e-07 (rank : 363)	NC score	0.464622 (rank : 260)
Query Neighborhood Hits	905	Target Neighborhood Hits	268	Shared Neighborhood Hits	262
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ITB3_MOUSE
θ value	1.53129e-07 (rank : 364)	NC score	0.432185 (rank : 342)
Query Neighborhood Hits	905	Target Neighborhood Hits	319	Shared Neighborhood Hits	275
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

MATN3_HUMAN
θ value	1.53129e-07 (rank : 365)	NC score	0.519505 (rank : 155)
Query Neighborhood Hits	905	Target Neighborhood Hits	268	Shared Neighborhood Hits	211
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

NFKB2_MOUSE
θ value	1.53129e-07 (rank : 366)	NC score	0.399048 (rank : 400)
Query Neighborhood Hits	905	Target Neighborhood Hits	326	Shared Neighborhood Hits	276
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ASB9_MOUSE
θ value	1.99992e-07 (rank : 367)	NC score	0.427709 (rank : 353)
Query Neighborhood Hits	905	Target Neighborhood Hits	257	Shared Neighborhood Hits	247
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ITB2_MOUSE
θ value	1.99992e-07 (rank : 368)	NC score	0.446697 (rank : 308)
Query Neighborhood Hits	905	Target Neighborhood Hits	326	Shared Neighborhood Hits	283
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB7_MOUSE
θ value	1.99992e-07 (rank : 369)	NC score	0.447436 (rank : 307)
Query Neighborhood Hits	905	Target Neighborhood Hits	277	Shared Neighborhood Hits	242
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

NAGPA_HUMAN
θ value	1.99992e-07 (rank : 370)	NC score	0.564428 (rank : 131)
Query Neighborhood Hits	905	Target Neighborhood Hits	282	Shared Neighborhood Hits	264
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

ADA33_HUMAN
θ value	2.61198e-07 (rank : 371)	NC score	0.160267 (rank : 680)
Query Neighborhood Hits	905	Target Neighborhood Hits	264	Shared Neighborhood Hits	178
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

AN30A_HUMAN
θ value	2.61198e-07 (rank : 372)	NC score	0.327486 (rank : 478)
Query Neighborhood Hits	905	Target Neighborhood Hits	1119	Shared Neighborhood Hits	275
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANR42_HUMAN
θ value	2.61198e-07 (rank : 373)	NC score	0.465514 (rank : 256)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

CDN2B_HUMAN
θ value	2.61198e-07 (rank : 374)	NC score	0.387655 (rank : 410)
Query Neighborhood Hits	905	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CREL1_MOUSE
θ value	2.61198e-07 (rank : 375)	NC score	0.667350 (rank : 80)
Query Neighborhood Hits	905	Target Neighborhood Hits	524	Shared Neighborhood Hits	301
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

ITB7_HUMAN
θ value	2.61198e-07 (rank : 376)	NC score	0.449233 (rank : 298)
Query Neighborhood Hits	905	Target Neighborhood Hits	290	Shared Neighborhood Hits	252
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

NTNG2_HUMAN
θ value	2.61198e-07 (rank : 377)	NC score	0.494694 (rank : 181)
Query Neighborhood Hits	905	Target Neighborhood Hits	276	Shared Neighborhood Hits	251
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ANR26_HUMAN
θ value	3.41135e-07 (rank : 378)	NC score	0.252318 (rank : 561)
Query Neighborhood Hits	905	Target Neighborhood Hits	1614	Shared Neighborhood Hits	308
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANS4B_HUMAN
θ value	3.41135e-07 (rank : 379)	NC score	0.420144 (rank : 369)
Query Neighborhood Hits	905	Target Neighborhood Hits	289	Shared Neighborhood Hits	257
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

MPP8_HUMAN
θ value	3.41135e-07 (rank : 380)	NC score	0.371814 (rank : 426)
Query Neighborhood Hits	905	Target Neighborhood Hits	948	Shared Neighborhood Hits	258
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NTNG1_HUMAN
θ value	3.41135e-07 (rank : 381)	NC score	0.471330 (rank : 239)
Query Neighborhood Hits	905	Target Neighborhood Hits	247	Shared Neighborhood Hits	215
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	3.41135e-07 (rank : 382)	NC score	0.471548 (rank : 237)
Query Neighborhood Hits	905	Target Neighborhood Hits	246	Shared Neighborhood Hits	217
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

PP16B_MOUSE
θ value	3.41135e-07 (rank : 383)	NC score	0.451637 (rank : 294)
Query Neighborhood Hits	905	Target Neighborhood Hits	302	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANR25_HUMAN
θ value	4.45536e-07 (rank : 384)	NC score	0.407199 (rank : 391)
Query Neighborhood Hits	905	Target Neighborhood Hits	350	Shared Neighborhood Hits	259
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANR25_MOUSE
θ value	4.45536e-07 (rank : 385)	NC score	0.394979 (rank : 404)
Query Neighborhood Hits	905	Target Neighborhood Hits	398	Shared Neighborhood Hits	257
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ASB11_HUMAN
θ value	4.45536e-07 (rank : 386)	NC score	0.439965 (rank : 324)
Query Neighborhood Hits	905	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

CORIN_HUMAN
θ value	4.45536e-07 (rank : 387)	NC score	0.203622 (rank : 620)
Query Neighborhood Hits	905	Target Neighborhood Hits	453	Shared Neighborhood Hits	233
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
θ value	4.45536e-07 (rank : 388)	NC score	0.181750 (rank : 656)
Query Neighborhood Hits	905	Target Neighborhood Hits	451	Shared Neighborhood Hits	220
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

FA7_MOUSE
θ value	4.45536e-07 (rank : 389)	NC score	0.237383 (rank : 579)
Query Neighborhood Hits	905	Target Neighborhood Hits	374	Shared Neighborhood Hits	220
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

LYAM2_HUMAN
θ value	4.45536e-07 (rank : 390)	NC score	0.347705 (rank : 457)
Query Neighborhood Hits	905	Target Neighborhood Hits	394	Shared Neighborhood Hits	258
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MEGF9_HUMAN
θ value	4.45536e-07 (rank : 391)	NC score	0.569424 (rank : 129)
Query Neighborhood Hits	905	Target Neighborhood Hits	557	Shared Neighborhood Hits	299
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CDN2C_HUMAN
θ value	5.81887e-07 (rank : 392)	NC score	0.468814 (rank : 246)
Query Neighborhood Hits	905	Target Neighborhood Hits	262	Shared Neighborhood Hits	259
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CDN2D_MOUSE
θ value	5.81887e-07 (rank : 393)	NC score	0.465602 (rank : 255)
Query Neighborhood Hits	905	Target Neighborhood Hits	267	Shared Neighborhood Hits	262
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ITB5_HUMAN
θ value	5.81887e-07 (rank : 394)	NC score	0.454589 (rank : 282)
Query Neighborhood Hits	905	Target Neighborhood Hits	310	Shared Neighborhood Hits	264
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

MATN3_MOUSE
θ value	5.81887e-07 (rank : 395)	NC score	0.521927 (rank : 153)
Query Neighborhood Hits	905	Target Neighborhood Hits	261	Shared Neighborhood Hits	217
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

SORL_HUMAN
θ value	5.81887e-07 (rank : 396)	NC score	0.358880 (rank : 443)
Query Neighborhood Hits	905	Target Neighborhood Hits	440	Shared Neighborhood Hits	245
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

ANKR5_HUMAN
θ value	9.92553e-07 (rank : 397)	NC score	0.444962 (rank : 318)
Query Neighborhood Hits	905	Target Neighborhood Hits	297	Shared Neighborhood Hits	280
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR39_MOUSE
θ value	9.92553e-07 (rank : 398)	NC score	0.465355 (rank : 257)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB12_HUMAN
θ value	9.92553e-07 (rank : 399)	NC score	0.434245 (rank : 336)
Query Neighborhood Hits	905	Target Neighborhood Hits	263	Shared Neighborhood Hits	258
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

BARD1_HUMAN
θ value	9.92553e-07 (rank : 400)	NC score	0.429271 (rank : 348)
Query Neighborhood Hits	905	Target Neighborhood Hits	427	Shared Neighborhood Hits	284
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ITB3_HUMAN
θ value	9.92553e-07 (rank : 401)	NC score	0.451625 (rank : 295)
Query Neighborhood Hits	905	Target Neighborhood Hits	325	Shared Neighborhood Hits	283
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

NAGPA_MOUSE
θ value	9.92553e-07 (rank : 402)	NC score	0.558465 (rank : 134)
Query Neighborhood Hits	905	Target Neighborhood Hits	308	Shared Neighborhood Hits	287
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

PGCB_MOUSE
θ value	9.92553e-07 (rank : 403)	NC score	0.284456 (rank : 522)
Query Neighborhood Hits	905	Target Neighborhood Hits	459	Shared Neighborhood Hits	200
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

VWF_HUMAN
θ value	9.92553e-07 (rank : 404)	NC score	0.313617 (rank : 485)
Query Neighborhood Hits	905	Target Neighborhood Hits	396	Shared Neighborhood Hits	253
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

FA9_HUMAN
θ value	1.29631e-06 (rank : 405)	NC score	0.286907 (rank : 513)
Query Neighborhood Hits	905	Target Neighborhood Hits	421	Shared Neighborhood Hits	264
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

IKBB_HUMAN
θ value	1.29631e-06 (rank : 406)	NC score	0.446032 (rank : 310)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

ASB11_MOUSE
θ value	1.69304e-06 (rank : 407)	NC score	0.435284 (rank : 333)
Query Neighborhood Hits	905	Target Neighborhood Hits	271	Shared Neighborhood Hits	255
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB4_HUMAN
θ value	1.69304e-06 (rank : 408)	NC score	0.445753 (rank : 315)
Query Neighborhood Hits	905	Target Neighborhood Hits	264	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

CDN2C_MOUSE
θ value	1.69304e-06 (rank : 409)	NC score	0.463307 (rank : 262)
Query Neighborhood Hits	905	Target Neighborhood Hits	270	Shared Neighborhood Hits	264
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ITB1_MOUSE
θ value	1.69304e-06 (rank : 410)	NC score	0.424882 (rank : 357)
Query Neighborhood Hits	905	Target Neighborhood Hits	283	Shared Neighborhood Hits	232
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

PROC_MOUSE
θ value	1.69304e-06 (rank : 411)	NC score	0.285338 (rank : 518)
Query Neighborhood Hits	905	Target Neighborhood Hits	426	Shared Neighborhood Hits	267
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

ASB1_HUMAN
θ value	2.21117e-06 (rank : 412)	NC score	0.438902 (rank : 327)
Query Neighborhood Hits	905	Target Neighborhood Hits	291	Shared Neighborhood Hits	269
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

KRA54_HUMAN
θ value	2.21117e-06 (rank : 413)	NC score	0.511362 (rank : 162)
Query Neighborhood Hits	905	Target Neighborhood Hits	270	Shared Neighborhood Hits	207
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LYAM3_MOUSE
θ value	2.21117e-06 (rank : 414)	NC score	0.370804 (rank : 428)
Query Neighborhood Hits	905	Target Neighborhood Hits	390	Shared Neighborhood Hits	261
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

USH1G_HUMAN
θ value	2.88788e-06 (rank : 415)	NC score	0.427893 (rank : 351)
Query Neighborhood Hits	905	Target Neighborhood Hits	267	Shared Neighborhood Hits	259
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	2.88788e-06 (rank : 416)	NC score	0.428308 (rank : 350)
Query Neighborhood Hits	905	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

GNPTA_HUMAN
θ value	3.77169e-06 (rank : 417)	NC score	0.138719 (rank : 728)
Query Neighborhood Hits	905	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

TRPV6_MOUSE
θ value	3.77169e-06 (rank : 418)	NC score	0.329687 (rank : 476)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	250
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ASB1_MOUSE
θ value	4.92598e-06 (rank : 419)	NC score	0.436944 (rank : 330)
Query Neighborhood Hits	905	Target Neighborhood Hits	292	Shared Neighborhood Hits	267
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

KR102_HUMAN
θ value	4.92598e-06 (rank : 420)	NC score	0.476626 (rank : 221)
Query Neighborhood Hits	905	Target Neighborhood Hits	264	Shared Neighborhood Hits	216
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

ASB14_MOUSE
θ value	6.43352e-06 (rank : 421)	NC score	0.460077 (rank : 269)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ANR41_HUMAN
θ value	8.40245e-06 (rank : 422)	NC score	0.432267 (rank : 341)
Query Neighborhood Hits	905	Target Neighborhood Hits	332	Shared Neighborhood Hits	262
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANS4B_MOUSE
θ value	8.40245e-06 (rank : 423)	NC score	0.411161 (rank : 385)
Query Neighborhood Hits	905	Target Neighborhood Hits	294	Shared Neighborhood Hits	253
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ATRN_HUMAN
θ value	8.40245e-06 (rank : 424)	NC score	0.415032 (rank : 378)
Query Neighborhood Hits	905	Target Neighborhood Hits	525	Shared Neighborhood Hits	303
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

CDN2B_MOUSE
θ value	8.40245e-06 (rank : 425)	NC score	0.398172 (rank : 401)
Query Neighborhood Hits	905	Target Neighborhood Hits	201	Shared Neighborhood Hits	197
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

ITB1_HUMAN
θ value	8.40245e-06 (rank : 426)	NC score	0.421526 (rank : 365)
Query Neighborhood Hits	905	Target Neighborhood Hits	298	Shared Neighborhood Hits	244
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

MTPN_HUMAN
θ value	8.40245e-06 (rank : 427)	NC score	0.450925 (rank : 296)
Query Neighborhood Hits	905	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

MTPN_MOUSE
θ value	8.40245e-06 (rank : 428)	NC score	0.452663 (rank : 289)
Query Neighborhood Hits	905	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

PROC_HUMAN
θ value	8.40245e-06 (rank : 429)	NC score	0.257024 (rank : 551)
Query Neighborhood Hits	905	Target Neighborhood Hits	406	Shared Neighborhood Hits	252
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

TRPV5_HUMAN
θ value	8.40245e-06 (rank : 430)	NC score	0.295960 (rank : 502)
Query Neighborhood Hits	905	Target Neighborhood Hits	261	Shared Neighborhood Hits	221
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ADA15_MOUSE
θ value	1.09739e-05 (rank : 431)	NC score	0.184012 (rank : 654)
Query Neighborhood Hits	905	Target Neighborhood Hits	324	Shared Neighborhood Hits	224
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ASB12_MOUSE
θ value	1.09739e-05 (rank : 432)	NC score	0.430265 (rank : 346)
Query Neighborhood Hits	905	Target Neighborhood Hits	261	Shared Neighborhood Hits	255
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

KR108_HUMAN
θ value	1.09739e-05 (rank : 433)	NC score	0.431963 (rank : 343)
Query Neighborhood Hits	905	Target Neighborhood Hits	226	Shared Neighborhood Hits	179
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KRA53_HUMAN
θ value	1.09739e-05 (rank : 434)	NC score	0.611236 (rank : 108)
Query Neighborhood Hits	905	Target Neighborhood Hits	331	Shared Neighborhood Hits	261
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

NFX1_HUMAN
θ value	1.09739e-05 (rank : 435)	NC score	0.343034 (rank : 465)
Query Neighborhood Hits	905	Target Neighborhood Hits	405	Shared Neighborhood Hits	183
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

CD248_MOUSE
θ value	1.43324e-05 (rank : 436)	NC score	0.534297 (rank : 142)
Query Neighborhood Hits	905	Target Neighborhood Hits	578	Shared Neighborhood Hits	246
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CENB2_HUMAN
θ value	1.43324e-05 (rank : 437)	NC score	0.294648 (rank : 504)
Query Neighborhood Hits	905	Target Neighborhood Hits	425	Shared Neighborhood Hits	252
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

KR105_HUMAN
θ value	1.43324e-05 (rank : 438)	NC score	0.466802 (rank : 253)
Query Neighborhood Hits	905	Target Neighborhood Hits	271	Shared Neighborhood Hits	217
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR10B_HUMAN
θ value	1.43324e-05 (rank : 439)	NC score	0.420637 (rank : 368)
Query Neighborhood Hits	905	Target Neighborhood Hits	269	Shared Neighborhood Hits	210
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LYAM2_MOUSE
θ value	1.43324e-05 (rank : 440)	NC score	0.346133 (rank : 461)
Query Neighborhood Hits	905	Target Neighborhood Hits	420	Shared Neighborhood Hits	280
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

ANR22_HUMAN
θ value	1.87187e-05 (rank : 441)	NC score	0.448657 (rank : 302)
Query Neighborhood Hits	905	Target Neighborhood Hits	243	Shared Neighborhood Hits	241
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

BARD1_MOUSE
θ value	1.87187e-05 (rank : 442)	NC score	0.421107 (rank : 366)
Query Neighborhood Hits	905	Target Neighborhood Hits	411	Shared Neighborhood Hits	279
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

KR10A_HUMAN
θ value	1.87187e-05 (rank : 443)	NC score	0.357500 (rank : 445)
Query Neighborhood Hits	905	Target Neighborhood Hits	232	Shared Neighborhood Hits	187
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

LYAM3_HUMAN
θ value	1.87187e-05 (rank : 444)	NC score	0.330256 (rank : 474)
Query Neighborhood Hits	905	Target Neighborhood Hits	378	Shared Neighborhood Hits	238
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

TRPV6_HUMAN
θ value	1.87187e-05 (rank : 445)	NC score	0.289366 (rank : 511)
Query Neighborhood Hits	905	Target Neighborhood Hits	262	Shared Neighborhood Hits	222
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

BCOR_HUMAN
θ value	2.44474e-05 (rank : 446)	NC score	0.374189 (rank : 424)
Query Neighborhood Hits	905	Target Neighborhood Hits	609	Shared Neighborhood Hits	270
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

KR10C_HUMAN
θ value	2.44474e-05 (rank : 447)	NC score	0.431283 (rank : 344)
Query Neighborhood Hits	905	Target Neighborhood Hits	219	Shared Neighborhood Hits	181
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

NTNG2_MOUSE
θ value	2.44474e-05 (rank : 448)	NC score	0.504984 (rank : 169)
Query Neighborhood Hits	905	Target Neighborhood Hits	276	Shared Neighborhood Hits	255
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

BCOR_MOUSE
θ value	3.19293e-05 (rank : 449)	NC score	0.379965 (rank : 415)
Query Neighborhood Hits	905	Target Neighborhood Hits	521	Shared Neighborhood Hits	269
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CD248_HUMAN
θ value	3.19293e-05 (rank : 450)	NC score	0.530335 (rank : 144)
Query Neighborhood Hits	905	Target Neighborhood Hits	679	Shared Neighborhood Hits	266
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD2A1_HUMAN
θ value	3.19293e-05 (rank : 451)	NC score	0.368994 (rank : 429)
Query Neighborhood Hits	905	Target Neighborhood Hits	196	Shared Neighborhood Hits	192
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

PGCB_HUMAN
θ value	3.19293e-05 (rank : 452)	NC score	0.265446 (rank : 545)
Query Neighborhood Hits	905	Target Neighborhood Hits	478	Shared Neighborhood Hits	192
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

POT14_HUMAN
θ value	3.19293e-05 (rank : 453)	NC score	0.391330 (rank : 408)
Query Neighborhood Hits	905	Target Neighborhood Hits	403	Shared Neighborhood Hits	266
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

CENG1_HUMAN
θ value	4.1701e-05 (rank : 454)	NC score	0.209030 (rank : 610)
Query Neighborhood Hits	905	Target Neighborhood Hits	544	Shared Neighborhood Hits	248
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

TPA_HUMAN
θ value	4.1701e-05 (rank : 455)	NC score	0.159963 (rank : 682)
Query Neighborhood Hits	905	Target Neighborhood Hits	324	Shared Neighborhood Hits	170
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

AN36A_HUMAN
θ value	5.44631e-05 (rank : 456)	NC score	0.435398 (rank : 332)
Query Neighborhood Hits	905	Target Neighborhood Hits	271	Shared Neighborhood Hits	264
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

CENB1_HUMAN
θ value	5.44631e-05 (rank : 457)	NC score	0.306439 (rank : 487)
Query Neighborhood Hits	905	Target Neighborhood Hits	383	Shared Neighborhood Hits	254
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

KR109_HUMAN
θ value	5.44631e-05 (rank : 458)	NC score	0.434226 (rank : 337)
Query Neighborhood Hits	905	Target Neighborhood Hits	226	Shared Neighborhood Hits	184
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

ANR46_MOUSE
θ value	7.1131e-05 (rank : 459)	NC score	0.452504 (rank : 291)
Query Neighborhood Hits	905	Target Neighborhood Hits	274	Shared Neighborhood Hits	266
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

KR414_HUMAN
θ value	7.1131e-05 (rank : 460)	NC score	0.353241 (rank : 447)
Query Neighborhood Hits	905	Target Neighborhood Hits	199	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

ANRA2_HUMAN
θ value	9.29e-05 (rank : 461)	NC score	0.437600 (rank : 329)
Query Neighborhood Hits	905	Target Neighborhood Hits	288	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANRA2_MOUSE
θ value	9.29e-05 (rank : 462)	NC score	0.439607 (rank : 326)
Query Neighborhood Hits	905	Target Neighborhood Hits	287	Shared Neighborhood Hits	271
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

GNPTA_MOUSE
θ value	9.29e-05 (rank : 463)	NC score	0.135979 (rank : 735)
Query Neighborhood Hits	905	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

RFXK_HUMAN
θ value	9.29e-05 (rank : 464)	NC score	0.432883 (rank : 340)
Query Neighborhood Hits	905	Target Neighborhood Hits	282	Shared Neighborhood Hits	263
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ADA18_MOUSE
θ value	0.000121331 (rank : 465)	NC score	0.158304 (rank : 687)
Query Neighborhood Hits	905	Target Neighborhood Hits	227	Shared Neighborhood Hits	180
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ASB6_MOUSE
θ value	0.000121331 (rank : 466)	NC score	0.421875 (rank : 364)
Query Neighborhood Hits	905	Target Neighborhood Hits	264	Shared Neighborhood Hits	246
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

HHIP_HUMAN
θ value	0.000121331 (rank : 467)	NC score	0.526514 (rank : 149)
Query Neighborhood Hits	905	Target Neighborhood Hits	249	Shared Neighborhood Hits	237
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ADAM8_MOUSE
θ value	0.000158464 (rank : 468)	NC score	0.200612 (rank : 624)
Query Neighborhood Hits	905	Target Neighborhood Hits	326	Shared Neighborhood Hits	211
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ANR46_HUMAN
θ value	0.000158464 (rank : 469)	NC score	0.453951 (rank : 283)
Query Neighborhood Hits	905	Target Neighborhood Hits	281	Shared Neighborhood Hits	273
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

HHIP_MOUSE
θ value	0.000158464 (rank : 470)	NC score	0.506651 (rank : 167)
Query Neighborhood Hits	905	Target Neighborhood Hits	219	Shared Neighborhood Hits	208
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KRA51_HUMAN
θ value	0.000158464 (rank : 471)	NC score	0.607648 (rank : 110)
Query Neighborhood Hits	905	Target Neighborhood Hits	288	Shared Neighborhood Hits	223
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

OSTF1_MOUSE
θ value	0.000158464 (rank : 472)	NC score	0.337868 (rank : 469)
Query Neighborhood Hits	905	Target Neighborhood Hits	467	Shared Neighborhood Hits	252
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

TMPS6_HUMAN
θ value	0.000158464 (rank : 473)	NC score	0.121453 (rank : 763)
Query Neighborhood Hits	905	Target Neighborhood Hits	338	Shared Neighborhood Hits	149
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ANKY2_MOUSE
θ value	0.00020696 (rank : 474)	NC score	0.392243 (rank : 407)
Query Neighborhood Hits	905	Target Neighborhood Hits	316	Shared Neighborhood Hits	255
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ATRN_MOUSE
θ value	0.00020696 (rank : 475)	NC score	0.413847 (rank : 380)
Query Neighborhood Hits	905	Target Neighborhood Hits	519	Shared Neighborhood Hits	300
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

KR103_HUMAN
θ value	0.00020696 (rank : 476)	NC score	0.347785 (rank : 456)
Query Neighborhood Hits	905	Target Neighborhood Hits	212	Shared Neighborhood Hits	171
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

LAMA3_HUMAN
θ value	0.00020696 (rank : 477)	NC score	0.423909 (rank : 359)
Query Neighborhood Hits	905	Target Neighborhood Hits	760	Shared Neighborhood Hits	278
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MUC2_HUMAN
θ value	0.00020696 (rank : 478)	NC score	0.204009 (rank : 619)
Query Neighborhood Hits	905	Target Neighborhood Hits	906	Shared Neighborhood Hits	204
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PERT_HUMAN
θ value	0.00020696 (rank : 479)	NC score	0.294338 (rank : 505)
Query Neighborhood Hits	905	Target Neighborhood Hits	221	Shared Neighborhood Hits	168
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

ADAM9_HUMAN
θ value	0.000270298 (rank : 480)	NC score	0.152327 (rank : 696)
Query Neighborhood Hits	905	Target Neighborhood Hits	243	Shared Neighborhood Hits	177
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM9_MOUSE
θ value	0.00035302 (rank : 481)	NC score	0.162548 (rank : 673)
Query Neighborhood Hits	905	Target Neighborhood Hits	325	Shared Neighborhood Hits	203
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ANKY2_HUMAN
θ value	0.00035302 (rank : 482)	NC score	0.405280 (rank : 393)
Query Neighborhood Hits	905	Target Neighborhood Hits	306	Shared Neighborhood Hits	257
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

KRA11_HUMAN
θ value	0.00035302 (rank : 483)	NC score	0.352377 (rank : 449)
Query Neighborhood Hits	905	Target Neighborhood Hits	155	Shared Neighborhood Hits	134
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

MMRN1_HUMAN
θ value	0.00035302 (rank : 484)	NC score	0.250793 (rank : 563)
Query Neighborhood Hits	905	Target Neighborhood Hits	636	Shared Neighborhood Hits	180
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

NET4_HUMAN
θ value	0.00035302 (rank : 485)	NC score	0.352433 (rank : 448)
Query Neighborhood Hits	905	Target Neighborhood Hits	191	Shared Neighborhood Hits	162
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

OSTF1_HUMAN
θ value	0.00035302 (rank : 486)	NC score	0.329885 (rank : 475)
Query Neighborhood Hits	905	Target Neighborhood Hits	466	Shared Neighborhood Hits	250
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

PERT_MOUSE
θ value	0.00035302 (rank : 487)	NC score	0.275038 (rank : 534)
Query Neighborhood Hits	905	Target Neighborhood Hits	221	Shared Neighborhood Hits	162
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGCA_HUMAN
θ value	0.00035302 (rank : 488)	NC score	0.209999 (rank : 609)
Query Neighborhood Hits	905	Target Neighborhood Hits	821	Shared Neighborhood Hits	199
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

TRPV5_MOUSE
θ value	0.00035302 (rank : 489)	NC score	0.301198 (rank : 496)
Query Neighborhood Hits	905	Target Neighborhood Hits	278	Shared Neighborhood Hits	244
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

CLPB_MOUSE
θ value	0.000461057 (rank : 490)	NC score	0.393883 (rank : 406)
Query Neighborhood Hits	905	Target Neighborhood Hits	289	Shared Neighborhood Hits	255
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

GIT1_HUMAN
θ value	0.000461057 (rank : 491)	NC score	0.285529 (rank : 517)
Query Neighborhood Hits	905	Target Neighborhood Hits	336	Shared Neighborhood Hits	245
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	0.000461057 (rank : 492)	NC score	0.287133 (rank : 512)
Query Neighborhood Hits	905	Target Neighborhood Hits	341	Shared Neighborhood Hits	245
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

KRA44_HUMAN
θ value	0.000461057 (rank : 493)	NC score	0.364427 (rank : 439)
Query Neighborhood Hits	905	Target Neighborhood Hits	162	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

AN13B_MOUSE
θ value	0.000602161 (rank : 494)	NC score	0.285115 (rank : 520)
Query Neighborhood Hits	905	Target Neighborhood Hits	276	Shared Neighborhood Hits	249
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ANR37_MOUSE
θ value	0.000602161 (rank : 495)	NC score	0.396728 (rank : 402)
Query Neighborhood Hits	905	Target Neighborhood Hits	237	Shared Neighborhood Hits	236
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ITB8_HUMAN
θ value	0.000602161 (rank : 496)	NC score	0.366736 (rank : 435)
Query Neighborhood Hits	905	Target Neighborhood Hits	280	Shared Neighborhood Hits	234
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KRA13_HUMAN
θ value	0.000602161 (rank : 497)	NC score	0.379423 (rank : 417)
Query Neighborhood Hits	905	Target Neighborhood Hits	144	Shared Neighborhood Hits	122
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

UROL1_HUMAN
θ value	0.000602161 (rank : 498)	NC score	0.267882 (rank : 544)
Query Neighborhood Hits	905	Target Neighborhood Hits	213	Shared Neighborhood Hits	140
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ASPP1_MOUSE
θ value	0.000786445 (rank : 499)	NC score	0.277512 (rank : 531)
Query Neighborhood Hits	905	Target Neighborhood Hits	1244	Shared Neighborhood Hits	282
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP2_HUMAN
θ value	0.000786445 (rank : 500)	NC score	0.291282 (rank : 507)
Query Neighborhood Hits	905	Target Neighborhood Hits	1156	Shared Neighborhood Hits	281
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CT086_HUMAN
θ value	0.000786445 (rank : 501)	NC score	0.457105 (rank : 275)
Query Neighborhood Hits	905	Target Neighborhood Hits	277	Shared Neighborhood Hits	269
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

PROP_MOUSE
θ value	0.000786445 (rank : 502)	NC score	0.077987 (rank : 853)
Query Neighborhood Hits	905	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

TPA_MOUSE
θ value	0.000786445 (rank : 503)	NC score	0.160284 (rank : 679)
Query Neighborhood Hits	905	Target Neighborhood Hits	335	Shared Neighborhood Hits	179
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ADA11_HUMAN
θ value	0.00102713 (rank : 504)	NC score	0.190070 (rank : 641)
Query Neighborhood Hits	905	Target Neighborhood Hits	259	Shared Neighborhood Hits	191
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

AN13B_HUMAN
θ value	0.00102713 (rank : 505)	NC score	0.283270 (rank : 523)
Query Neighborhood Hits	905	Target Neighborhood Hits	265	Shared Neighborhood Hits	249
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ASB6_HUMAN
θ value	0.00102713 (rank : 506)	NC score	0.413990 (rank : 379)
Query Neighborhood Hits	905	Target Neighborhood Hits	256	Shared Neighborhood Hits	248
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CENB5_HUMAN
θ value	0.00102713 (rank : 507)	NC score	0.303315 (rank : 494)
Query Neighborhood Hits	905	Target Neighborhood Hits	395	Shared Neighborhood Hits	259
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CNTP4_MOUSE
θ value	0.00102713 (rank : 508)	NC score	0.247354 (rank : 566)
Query Neighborhood Hits	905	Target Neighborhood Hits	193	Shared Neighborhood Hits	149
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

DDEF1_MOUSE
θ value	0.00102713 (rank : 509)	NC score	0.160722 (rank : 676)
Query Neighborhood Hits	905	Target Neighborhood Hits	592	Shared Neighborhood Hits	195
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

KRA45_HUMAN
θ value	0.00102713 (rank : 510)	NC score	0.360867 (rank : 442)
Query Neighborhood Hits	905	Target Neighborhood Hits	194	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

VASN_HUMAN
θ value	0.00102713 (rank : 511)	NC score	0.159301 (rank : 684)
Query Neighborhood Hits	905	Target Neighborhood Hits	449	Shared Neighborhood Hits	143
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ZAN_HUMAN
θ value	0.00102713 (rank : 512)	NC score	0.348416 (rank : 455)
Query Neighborhood Hits	905	Target Neighborhood Hits	679	Shared Neighborhood Hits	315
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ADA19_HUMAN
θ value	0.00134147 (rank : 513)	NC score	0.166748 (rank : 671)
Query Neighborhood Hits	905	Target Neighborhood Hits	381	Shared Neighborhood Hits	192
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ANR33_MOUSE
θ value	0.00134147 (rank : 514)	NC score	0.400420 (rank : 397)
Query Neighborhood Hits	905	Target Neighborhood Hits	225	Shared Neighborhood Hits	219
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CENG1_MOUSE
θ value	0.00134147 (rank : 515)	NC score	0.205666 (rank : 616)
Query Neighborhood Hits	905	Target Neighborhood Hits	531	Shared Neighborhood Hits	244
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG3_HUMAN
θ value	0.00134147 (rank : 516)	NC score	0.190133 (rank : 640)
Query Neighborhood Hits	905	Target Neighborhood Hits	455	Shared Neighborhood Hits	229
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	0.00134147 (rank : 517)	NC score	0.189997 (rank : 642)
Query Neighborhood Hits	905	Target Neighborhood Hits	467	Shared Neighborhood Hits	230
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CNTP4_HUMAN
θ value	0.00134147 (rank : 518)	NC score	0.240216 (rank : 571)
Query Neighborhood Hits	905	Target Neighborhood Hits	187	Shared Neighborhood Hits	130
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

ADA30_HUMAN
θ value	0.00175202 (rank : 519)	NC score	0.144455 (rank : 712)
Query Neighborhood Hits	905	Target Neighborhood Hits	391	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADAM8_HUMAN
θ value	0.00175202 (rank : 520)	NC score	0.185024 (rank : 652)
Query Neighborhood Hits	905	Target Neighborhood Hits	327	Shared Neighborhood Hits	228
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ANR43_MOUSE
θ value	0.00175202 (rank : 521)	NC score	0.333588 (rank : 472)
Query Neighborhood Hits	905	Target Neighborhood Hits	214	Shared Neighborhood Hits	204
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CNTP2_HUMAN
θ value	0.00175202 (rank : 522)	NC score	0.253575 (rank : 558)
Query Neighborhood Hits	905	Target Neighborhood Hits	199	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	0.00175202 (rank : 523)	NC score	0.256449 (rank : 553)
Query Neighborhood Hits	905	Target Neighborhood Hits	194	Shared Neighborhood Hits	145
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

DDEF2_HUMAN
θ value	0.00175202 (rank : 524)	NC score	0.218650 (rank : 596)
Query Neighborhood Hits	905	Target Neighborhood Hits	599	Shared Neighborhood Hits	236
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	0.00175202 (rank : 525)	NC score	0.217468 (rank : 598)
Query Neighborhood Hits	905	Target Neighborhood Hits	625	Shared Neighborhood Hits	239
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

IASPP_HUMAN
θ value	0.00175202 (rank : 526)	NC score	0.305572 (rank : 488)
Query Neighborhood Hits	905	Target Neighborhood Hits	688	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

KRA15_HUMAN
θ value	0.00175202 (rank : 527)	NC score	0.327347 (rank : 479)
Query Neighborhood Hits	905	Target Neighborhood Hits	126	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

TEX14_HUMAN
θ value	0.00175202 (rank : 528)	NC score	0.213117 (rank : 604)
Query Neighborhood Hits	905	Target Neighborhood Hits	1103	Shared Neighborhood Hits	260
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ADA10_HUMAN
θ value	0.00228821 (rank : 529)	NC score	0.153981 (rank : 694)
Query Neighborhood Hits	905	Target Neighborhood Hits	189	Shared Neighborhood Hits	140
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

CFC1_MOUSE
θ value	0.00228821 (rank : 530)	NC score	0.389925 (rank : 409)
Query Neighborhood Hits	905	Target Neighborhood Hits	125	Shared Neighborhood Hits	124
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CNTP3_HUMAN
θ value	0.00228821 (rank : 531)	NC score	0.235585 (rank : 583)
Query Neighborhood Hits	905	Target Neighborhood Hits	195	Shared Neighborhood Hits	137
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

EPHB4_HUMAN
θ value	0.00228821 (rank : 532)	NC score	0.056841 (rank : 946)
Query Neighborhood Hits	905	Target Neighborhood Hits	1056	Shared Neighborhood Hits	169
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

IASPP_MOUSE
θ value	0.00228821 (rank : 533)	NC score	0.271555 (rank : 540)
Query Neighborhood Hits	905	Target Neighborhood Hits	1024	Shared Neighborhood Hits	280
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

KR124_HUMAN
θ value	0.00228821 (rank : 534)	NC score	0.155748 (rank : 691)
Query Neighborhood Hits	905	Target Neighborhood Hits	124	Shared Neighborhood Hits	94
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KRA57_HUMAN
θ value	0.00228821 (rank : 535)	NC score	0.528814 (rank : 146)
Query Neighborhood Hits	905	Target Neighborhood Hits	269	Shared Neighborhood Hits	216
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

NET2_HUMAN
θ value	0.00228821 (rank : 536)	NC score	0.345082 (rank : 463)
Query Neighborhood Hits	905	Target Neighborhood Hits	194	Shared Neighborhood Hits	154
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

PAP2_HUMAN
θ value	0.00228821 (rank : 537)	NC score	0.080892 (rank : 842)
Query Neighborhood Hits	905	Target Neighborhood Hits	106	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

ADA15_HUMAN
θ value	0.00298849 (rank : 538)	NC score	0.168183 (rank : 668)
Query Neighborhood Hits	905	Target Neighborhood Hits	288	Shared Neighborhood Hits	213
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ANR43_HUMAN
θ value	0.00298849 (rank : 539)	NC score	0.343367 (rank : 464)
Query Neighborhood Hits	905	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

FSTL3_MOUSE
θ value	0.00298849 (rank : 540)	NC score	0.175899 (rank : 660)
Query Neighborhood Hits	905	Target Neighborhood Hits	152	Shared Neighborhood Hits	101
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

KR412_HUMAN
θ value	0.00298849 (rank : 541)	NC score	0.333360 (rank : 473)
Query Neighborhood Hits	905	Target Neighborhood Hits	178	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR511_HUMAN
θ value	0.00298849 (rank : 542)	NC score	0.464330 (rank : 261)
Query Neighborhood Hits	905	Target Neighborhood Hits	231	Shared Neighborhood Hits	181
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA52_HUMAN
θ value	0.00298849 (rank : 543)	NC score	0.448659 (rank : 301)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	190
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

NET4_MOUSE
θ value	0.00298849 (rank : 544)	NC score	0.346497 (rank : 460)
Query Neighborhood Hits	905	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

UROL1_MOUSE
θ value	0.00298849 (rank : 545)	NC score	0.286533 (rank : 516)
Query Neighborhood Hits	905	Target Neighborhood Hits	235	Shared Neighborhood Hits	152
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ANR37_HUMAN
θ value	0.00390308 (rank : 546)	NC score	0.407375 (rank : 390)
Query Neighborhood Hits	905	Target Neighborhood Hits	247	Shared Neighborhood Hits	245
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

CLR59_HUMAN
θ value	0.00390308 (rank : 547)	NC score	0.176148 (rank : 659)
Query Neighborhood Hits	905	Target Neighborhood Hits	163	Shared Neighborhood Hits	141
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

CO8B_MOUSE
θ value	0.00390308 (rank : 548)	NC score	0.185413 (rank : 651)
Query Neighborhood Hits	905	Target Neighborhood Hits	224	Shared Neighborhood Hits	128
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

GIT2_MOUSE
θ value	0.00390308 (rank : 549)	NC score	0.289600 (rank : 510)
Query Neighborhood Hits	905	Target Neighborhood Hits	323	Shared Neighborhood Hits	250
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

RELN_HUMAN
θ value	0.00390308 (rank : 550)	NC score	0.229484 (rank : 588)
Query Neighborhood Hits	905	Target Neighborhood Hits	233	Shared Neighborhood Hits	189
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

TRPV3_MOUSE
θ value	0.00390308 (rank : 551)	NC score	0.165509 (rank : 672)
Query Neighborhood Hits	905	Target Neighborhood Hits	188	Shared Neighborhood Hits	129
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

ABTB2_HUMAN
θ value	0.00509761 (rank : 552)	NC score	0.305551 (rank : 489)
Query Neighborhood Hits	905	Target Neighborhood Hits	391	Shared Neighborhood Hits	236
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ADA25_MOUSE
θ value	0.00509761 (rank : 553)	NC score	0.130867 (rank : 746)
Query Neighborhood Hits	905	Target Neighborhood Hits	213	Shared Neighborhood Hits	161
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ANR40_MOUSE
θ value	0.00509761 (rank : 554)	NC score	0.342914 (rank : 466)
Query Neighborhood Hits	905	Target Neighborhood Hits	228	Shared Neighborhood Hits	204
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

CO7_HUMAN
θ value	0.00509761 (rank : 555)	NC score	0.202132 (rank : 621)
Query Neighborhood Hits	905	Target Neighborhood Hits	278	Shared Neighborhood Hits	149
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

GIT2_HUMAN
θ value	0.00509761 (rank : 556)	NC score	0.258146 (rank : 549)
Query Neighborhood Hits	905	Target Neighborhood Hits	381	Shared Neighborhood Hits	242
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

KRA58_HUMAN
θ value	0.00509761 (rank : 557)	NC score	0.579264 (rank : 125)
Query Neighborhood Hits	905	Target Neighborhood Hits	324	Shared Neighborhood Hits	250
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

MEP1A_MOUSE
θ value	0.00509761 (rank : 558)	NC score	0.214911 (rank : 602)
Query Neighborhood Hits	905	Target Neighborhood Hits	166	Shared Neighborhood Hits	135
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

TRPV3_HUMAN
θ value	0.00509761 (rank : 559)	NC score	0.160165 (rank : 681)
Query Neighborhood Hits	905	Target Neighborhood Hits	198	Shared Neighborhood Hits	140
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

ANR40_HUMAN
θ value	0.00665767 (rank : 560)	NC score	0.348700 (rank : 454)
Query Neighborhood Hits	905	Target Neighborhood Hits	224	Shared Neighborhood Hits	201
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ASPP1_HUMAN
θ value	0.00665767 (rank : 561)	NC score	0.285259 (rank : 519)
Query Neighborhood Hits	905	Target Neighborhood Hits	956	Shared Neighborhood Hits	270
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

EMR3_HUMAN
θ value	0.00665767 (rank : 562)	NC score	0.296346 (rank : 500)
Query Neighborhood Hits	905	Target Neighborhood Hits	245	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

KR510_HUMAN
θ value	0.00665767 (rank : 563)	NC score	0.405742 (rank : 392)
Query Neighborhood Hits	905	Target Neighborhood Hits	217	Shared Neighborhood Hits	164
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRIT1_HUMAN
θ value	0.00665767 (rank : 564)	NC score	0.367795 (rank : 431)
Query Neighborhood Hits	905	Target Neighborhood Hits	258	Shared Neighborhood Hits	219
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

MCSP_MOUSE
θ value	0.00665767 (rank : 565)	NC score	0.167434 (rank : 669)
Query Neighborhood Hits	905	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MFGM_HUMAN
θ value	0.00665767 (rank : 566)	NC score	0.237134 (rank : 580)
Query Neighborhood Hits	905	Target Neighborhood Hits	150	Shared Neighborhood Hits	129
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

NET2_MOUSE
θ value	0.00665767 (rank : 567)	NC score	0.347675 (rank : 458)
Query Neighborhood Hits	905	Target Neighborhood Hits	193	Shared Neighborhood Hits	161
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NRG2_MOUSE
θ value	0.00665767 (rank : 568)	NC score	0.204466 (rank : 617)
Query Neighborhood Hits	905	Target Neighborhood Hits	392	Shared Neighborhood Hits	130
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRX1A_HUMAN
θ value	0.00665767 (rank : 569)	NC score	0.274964 (rank : 535)
Query Neighborhood Hits	905	Target Neighborhood Hits	170	Shared Neighborhood Hits	138
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	0.00665767 (rank : 570)	NC score	0.274090 (rank : 536)
Query Neighborhood Hits	905	Target Neighborhood Hits	164	Shared Neighborhood Hits	137
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

POT22_HUMAN
θ value	0.00665767 (rank : 571)	NC score	0.372295 (rank : 425)
Query Neighborhood Hits	905	Target Neighborhood Hits	266	Shared Neighborhood Hits	257
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

ST14_MOUSE
θ value	0.00665767 (rank : 572)	NC score	0.159834 (rank : 683)
Query Neighborhood Hits	905	Target Neighborhood Hits	419	Shared Neighborhood Hits	207
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ADA32_HUMAN
θ value	0.00869519 (rank : 573)	NC score	0.132420 (rank : 743)
Query Neighborhood Hits	905	Target Neighborhood Hits	216	Shared Neighborhood Hits	165
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

NRX3A_HUMAN
θ value	0.00869519 (rank : 574)	NC score	0.260325 (rank : 548)
Query Neighborhood Hits	905	Target Neighborhood Hits	164	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

TEFF2_HUMAN
θ value	0.00869519 (rank : 575)	NC score	0.304325 (rank : 493)
Query Neighborhood Hits	905	Target Neighborhood Hits	211	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

ABTB2_MOUSE
θ value	0.0113563 (rank : 576)	NC score	0.297895 (rank : 498)
Query Neighborhood Hits	905	Target Neighborhood Hits	414	Shared Neighborhood Hits	238
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ADA12_HUMAN
θ value	0.0113563 (rank : 577)	NC score	0.138825 (rank : 727)
Query Neighborhood Hits	905	Target Neighborhood Hits	224	Shared Neighborhood Hits	152
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ANR32_MOUSE
θ value	0.0113563 (rank : 578)	NC score	0.399923 (rank : 398)
Query Neighborhood Hits	905	Target Neighborhood Hits	285	Shared Neighborhood Hits	259
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ERBB4_HUMAN
θ value	0.0113563 (rank : 579)	NC score	0.027916 (rank : 1027)
Query Neighborhood Hits	905	Target Neighborhood Hits	910	Shared Neighborhood Hits	103
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

GP179_HUMAN
θ value	0.0113563 (rank : 580)	NC score	0.067972 (rank : 885)
Query Neighborhood Hits	905	Target Neighborhood Hits	372	Shared Neighborhood Hits	55
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

NRX2A_HUMAN
θ value	0.0113563 (rank : 581)	NC score	0.252718 (rank : 559)
Query Neighborhood Hits	905	Target Neighborhood Hits	614	Shared Neighborhood Hits	174
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

RELN_MOUSE
θ value	0.0113563 (rank : 582)	NC score	0.238556 (rank : 575)
Query Neighborhood Hits	905	Target Neighborhood Hits	235	Shared Neighborhood Hits	192
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

RFXK_MOUSE
θ value	0.0113563 (rank : 583)	NC score	0.423024 (rank : 361)
Query Neighborhood Hits	905	Target Neighborhood Hits	273	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

TRPV2_HUMAN
θ value	0.0113563 (rank : 584)	NC score	0.141798 (rank : 718)
Query Neighborhood Hits	905	Target Neighborhood Hits	130	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

ADA10_MOUSE
θ value	0.0148317 (rank : 585)	NC score	0.147012 (rank : 706)
Query Neighborhood Hits	905	Target Neighborhood Hits	194	Shared Neighborhood Hits	141
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA11_MOUSE
θ value	0.0148317 (rank : 586)	NC score	0.188778 (rank : 647)
Query Neighborhood Hits	905	Target Neighborhood Hits	263	Shared Neighborhood Hits	192
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ANR33_HUMAN
θ value	0.0148317 (rank : 587)	NC score	0.383880 (rank : 411)
Query Neighborhood Hits	905	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

DGKZ_HUMAN
θ value	0.0148317 (rank : 588)	NC score	0.201794 (rank : 622)
Query Neighborhood Hits	905	Target Neighborhood Hits	551	Shared Neighborhood Hits	218
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKZ_MOUSE
θ value	0.0148317 (rank : 589)	NC score	0.193401 (rank : 633)
Query Neighborhood Hits	905	Target Neighborhood Hits	542	Shared Neighborhood Hits	203
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

GLSL_MOUSE
θ value	0.0148317 (rank : 590)	NC score	0.252505 (rank : 560)
Query Neighborhood Hits	905	Target Neighborhood Hits	212	Shared Neighborhood Hits	200
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

KRA99_HUMAN
θ value	0.0148317 (rank : 591)	NC score	0.322728 (rank : 481)
Query Neighborhood Hits	905	Target Neighborhood Hits	173	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

TMPS6_MOUSE
θ value	0.0148317 (rank : 592)	NC score	0.113694 (rank : 773)
Query Neighborhood Hits	905	Target Neighborhood Hits	341	Shared Neighborhood Hits	150
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

CENG2_MOUSE
θ value	0.0193708 (rank : 593)	NC score	0.193103 (rank : 634)
Query Neighborhood Hits	905	Target Neighborhood Hits	463	Shared Neighborhood Hits	251
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

EPHB4_MOUSE
θ value	0.0193708 (rank : 594)	NC score	0.039233 (rank : 1009)
Query Neighborhood Hits	905	Target Neighborhood Hits	1013	Shared Neighborhood Hits	139
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

GLSL_HUMAN
θ value	0.0193708 (rank : 595)	NC score	0.257148 (rank : 550)
Query Neighborhood Hits	905	Target Neighborhood Hits	211	Shared Neighborhood Hits	200
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

KRA47_HUMAN
θ value	0.0193708 (rank : 596)	NC score	0.349685 (rank : 453)
Query Neighborhood Hits	905	Target Neighborhood Hits	204	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

MASP2_HUMAN
θ value	0.0193708 (rank : 597)	NC score	0.131215 (rank : 745)
Query Neighborhood Hits	905	Target Neighborhood Hits	364	Shared Neighborhood Hits	156
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

TDGF1_HUMAN
θ value	0.0193708 (rank : 598)	NC score	0.328115 (rank : 477)
Query Neighborhood Hits	905	Target Neighborhood Hits	132	Shared Neighborhood Hits	130
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

ADA18_HUMAN
θ value	0.0252991 (rank : 599)	NC score	0.137199 (rank : 731)
Query Neighborhood Hits	905	Target Neighborhood Hits	184	Shared Neighborhood Hits	148
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADM1B_MOUSE
θ value	0.0252991 (rank : 600)	NC score	0.124151 (rank : 760)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	152
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

CFC1_HUMAN
θ value	0.0252991 (rank : 601)	NC score	0.410758 (rank : 387)
Query Neighborhood Hits	905	Target Neighborhood Hits	148	Shared Neighborhood Hits	146
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

KRA42_HUMAN
θ value	0.0252991 (rank : 602)	NC score	0.255389 (rank : 554)
Query Neighborhood Hits	905	Target Neighborhood Hits	149	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA55_HUMAN
θ value	0.0252991 (rank : 603)	NC score	0.518323 (rank : 156)
Query Neighborhood Hits	905	Target Neighborhood Hits	257	Shared Neighborhood Hits	209
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LYAM1_MOUSE
θ value	0.0252991 (rank : 604)	NC score	0.286884 (rank : 514)
Query Neighborhood Hits	905	Target Neighborhood Hits	332	Shared Neighborhood Hits	210
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MEP1A_HUMAN
θ value	0.0252991 (rank : 605)	NC score	0.207714 (rank : 613)
Query Neighborhood Hits	905	Target Neighborhood Hits	162	Shared Neighborhood Hits	136
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

PGH2_HUMAN
θ value	0.0252991 (rank : 606)	NC score	0.198740 (rank : 626)
Query Neighborhood Hits	905	Target Neighborhood Hits	103	Shared Neighborhood Hits	93
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

RSNL2_MOUSE
θ value	0.0252991 (rank : 607)	NC score	0.110585 (rank : 776)
Query Neighborhood Hits	905	Target Neighborhood Hits	129	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TEFF2_MOUSE
θ value	0.0252991 (rank : 608)	NC score	0.305245 (rank : 491)
Query Neighborhood Hits	905	Target Neighborhood Hits	214	Shared Neighborhood Hits	155
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEX14_MOUSE
θ value	0.0252991 (rank : 609)	NC score	0.212251 (rank : 605)
Query Neighborhood Hits	905	Target Neighborhood Hits	1333	Shared Neighborhood Hits	278
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ADA23_HUMAN
θ value	0.0330416 (rank : 610)	NC score	0.179064 (rank : 657)
Query Neighborhood Hits	905	Target Neighborhood Hits	235	Shared Neighborhood Hits	182
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

CNTP1_HUMAN
θ value	0.0330416 (rank : 611)	NC score	0.216752 (rank : 599)
Query Neighborhood Hits	905	Target Neighborhood Hits	196	Shared Neighborhood Hits	128
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CO6_HUMAN
θ value	0.0330416 (rank : 612)	NC score	0.201176 (rank : 623)
Query Neighborhood Hits	905	Target Neighborhood Hits	331	Shared Neighborhood Hits	185
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

KRA93_HUMAN
θ value	0.0330416 (rank : 613)	NC score	0.365850 (rank : 436)
Query Neighborhood Hits	905	Target Neighborhood Hits	203	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRIT1_MOUSE
θ value	0.0330416 (rank : 614)	NC score	0.368110 (rank : 430)
Query Neighborhood Hits	905	Target Neighborhood Hits	258	Shared Neighborhood Hits	226
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

LCE1C_HUMAN
θ value	0.0330416 (rank : 615)	NC score	0.327226 (rank : 480)
Query Neighborhood Hits	905	Target Neighborhood Hits	65	Shared Neighborhood Hits	46
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

NRG1_HUMAN
θ value	0.0330416 (rank : 616)	NC score	0.205816 (rank : 615)
Query Neighborhood Hits	905	Target Neighborhood Hits	285	Shared Neighborhood Hits	105
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

TDGF1_MOUSE
θ value	0.0330416 (rank : 617)	NC score	0.378970 (rank : 418)
Query Neighborhood Hits	905	Target Neighborhood Hits	146	Shared Neighborhood Hits	144
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TLL2_HUMAN
θ value	0.0330416 (rank : 618)	NC score	0.233080 (rank : 584)
Query Neighborhood Hits	905	Target Neighborhood Hits	241	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

VASN_MOUSE
θ value	0.0330416 (rank : 619)	NC score	0.145556 (rank : 710)
Query Neighborhood Hits	905	Target Neighborhood Hits	426	Shared Neighborhood Hits	130
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

BMP1_HUMAN
θ value	0.0431538 (rank : 620)	NC score	0.238408 (rank : 577)
Query Neighborhood Hits	905	Target Neighborhood Hits	233	Shared Neighborhood Hits	182
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	0.0431538 (rank : 621)	NC score	0.240183 (rank : 572)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	183
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CD320_HUMAN
θ value	0.0431538 (rank : 622)	NC score	0.158886 (rank : 685)
Query Neighborhood Hits	905	Target Neighborhood Hits	103	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

ERBB3_HUMAN
θ value	0.0431538 (rank : 623)	NC score	0.029874 (rank : 1024)
Query Neighborhood Hits	905	Target Neighborhood Hits	918	Shared Neighborhood Hits	129
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

LRP3_HUMAN
θ value	0.0431538 (rank : 624)	NC score	0.176939 (rank : 658)
Query Neighborhood Hits	905	Target Neighborhood Hits	280	Shared Neighborhood Hits	140
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LYAM1_HUMAN
θ value	0.0431538 (rank : 625)	NC score	0.280051 (rank : 528)
Query Neighborhood Hits	905	Target Neighborhood Hits	315	Shared Neighborhood Hits	205
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

NRG2_HUMAN
θ value	0.0431538 (rank : 626)	NC score	0.171938 (rank : 664)
Query Neighborhood Hits	905	Target Neighborhood Hits	419	Shared Neighborhood Hits	119
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

TDGF2_HUMAN
θ value	0.0431538 (rank : 627)	NC score	0.322422 (rank : 482)
Query Neighborhood Hits	905	Target Neighborhood Hits	131	Shared Neighborhood Hits	126
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

UROK_HUMAN
θ value	0.0431538 (rank : 628)	NC score	0.098014 (rank : 799)
Query Neighborhood Hits	905	Target Neighborhood Hits	272	Shared Neighborhood Hits	121
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

ANKZ1_MOUSE
θ value	0.0563607 (rank : 629)	NC score	0.191763 (rank : 637)
Query Neighborhood Hits	905	Target Neighborhood Hits	208	Shared Neighborhood Hits	151
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

APR3_MOUSE
θ value	0.0563607 (rank : 630)	NC score	0.192398 (rank : 636)
Query Neighborhood Hits	905	Target Neighborhood Hits	61	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

MUC13_MOUSE
θ value	0.0563607 (rank : 631)	NC score	0.281744 (rank : 524)
Query Neighborhood Hits	905	Target Neighborhood Hits	447	Shared Neighborhood Hits	175
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PGH2_MOUSE
θ value	0.0563607 (rank : 632)	NC score	0.211953 (rank : 606)
Query Neighborhood Hits	905	Target Neighborhood Hits	113	Shared Neighborhood Hits	104
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

TRPV4_HUMAN
θ value	0.0563607 (rank : 633)	NC score	0.097476 (rank : 801)
Query Neighborhood Hits	905	Target Neighborhood Hits	150	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

ANKZ1_HUMAN
θ value	0.0736092 (rank : 634)	NC score	0.187218 (rank : 648)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	158
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

C1RA_MOUSE
θ value	0.0736092 (rank : 635)	NC score	0.154163 (rank : 693)
Query Neighborhood Hits	905	Target Neighborhood Hits	379	Shared Neighborhood Hits	171
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	0.0736092 (rank : 636)	NC score	0.151741 (rank : 698)
Query Neighborhood Hits	905	Target Neighborhood Hits	380	Shared Neighborhood Hits	170
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

CENG2_HUMAN
θ value	0.0736092 (rank : 637)	NC score	0.192465 (rank : 635)
Query Neighborhood Hits	905	Target Neighborhood Hits	471	Shared Neighborhood Hits	253
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CLPB_HUMAN
θ value	0.0736092 (rank : 638)	NC score	0.334897 (rank : 471)
Query Neighborhood Hits	905	Target Neighborhood Hits	265	Shared Neighborhood Hits	236
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

CNTP1_MOUSE
θ value	0.0736092 (rank : 639)	NC score	0.210088 (rank : 607)
Query Neighborhood Hits	905	Target Neighborhood Hits	183	Shared Neighborhood Hits	121
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

DGKI_HUMAN
θ value	0.0736092 (rank : 640)	NC score	0.190617 (rank : 638)
Query Neighborhood Hits	905	Target Neighborhood Hits	609	Shared Neighborhood Hits	219
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

IKBL_HUMAN
θ value	0.0736092 (rank : 641)	NC score	0.197399 (rank : 628)
Query Neighborhood Hits	905	Target Neighborhood Hits	168	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	0.0736092 (rank : 642)	NC score	0.194118 (rank : 632)
Query Neighborhood Hits	905	Target Neighborhood Hits	196	Shared Neighborhood Hits	139
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

KRA24_HUMAN
θ value	0.0736092 (rank : 643)	NC score	0.189598 (rank : 644)
Query Neighborhood Hits	905	Target Neighborhood Hits	192	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

PCSK6_HUMAN
θ value	0.0736092 (rank : 644)	NC score	0.189691 (rank : 643)
Query Neighborhood Hits	905	Target Neighborhood Hits	298	Shared Neighborhood Hits	164
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

TRPV4_MOUSE
θ value	0.0736092 (rank : 645)	NC score	0.086086 (rank : 824)
Query Neighborhood Hits	905	Target Neighborhood Hits	117	Shared Neighborhood Hits	76
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

UROK_MOUSE
θ value	0.0736092 (rank : 646)	NC score	0.096271 (rank : 805)
Query Neighborhood Hits	905	Target Neighborhood Hits	273	Shared Neighborhood Hits	125
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

ADA24_MOUSE
θ value	0.0961366 (rank : 647)	NC score	0.128507 (rank : 753)
Query Neighborhood Hits	905	Target Neighborhood Hits	230	Shared Neighborhood Hits	178
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

AN13C_HUMAN
θ value	0.0961366 (rank : 648)	NC score	0.263180 (rank : 546)
Query Neighborhood Hits	905	Target Neighborhood Hits	241	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

EPHB1_HUMAN
θ value	0.0961366 (rank : 649)	NC score	0.025437 (rank : 1032)
Query Neighborhood Hits	905	Target Neighborhood Hits	988	Shared Neighborhood Hits	110
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

LCE1B_HUMAN
θ value	0.0961366 (rank : 650)	NC score	0.336967 (rank : 470)
Query Neighborhood Hits	905	Target Neighborhood Hits	58	Shared Neighborhood Hits	43
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

NRG4_MOUSE
θ value	0.0961366 (rank : 651)	NC score	0.207967 (rank : 612)
Query Neighborhood Hits	905	Target Neighborhood Hits	79	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

PAPPA_HUMAN
θ value	0.0961366 (rank : 652)	NC score	0.109021 (rank : 779)
Query Neighborhood Hits	905	Target Neighborhood Hits	161	Shared Neighborhood Hits	86
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

TLL1_MOUSE
θ value	0.0961366 (rank : 653)	NC score	0.238535 (rank : 576)
Query Neighborhood Hits	905	Target Neighborhood Hits	237	Shared Neighborhood Hits	181
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TNR1B_HUMAN
θ value	0.0961366 (rank : 654)	NC score	0.054528 (rank : 961)
Query Neighborhood Hits	905	Target Neighborhood Hits	127	Shared Neighborhood Hits	56
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TYPH_HUMAN
θ value	0.0961366 (rank : 655)	NC score	0.018467 (rank : 1044)
Query Neighborhood Hits	905	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P19971, Q13390, Q8WVB7	Gene names	ECGF1
Domain Architecture
Description	Thymidine phosphorylase precursor (EC 2.4.2.4) (TdRPase) (TP) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (Gliostatin).

ADA21_MOUSE
θ value	0.125558 (rank : 656)	NC score	0.135920 (rank : 736)
Query Neighborhood Hits	905	Target Neighborhood Hits	172	Shared Neighborhood Hits	132
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

APXL_HUMAN
θ value	0.125558 (rank : 657)	NC score	0.006674 (rank : 1071)
Query Neighborhood Hits	905	Target Neighborhood Hits	553	Shared Neighborhood Hits	19
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CO8A_MOUSE
θ value	0.125558 (rank : 658)	NC score	0.132658 (rank : 742)
Query Neighborhood Hits	905	Target Neighborhood Hits	182	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	0.125558 (rank : 659)	NC score	0.144274 (rank : 714)
Query Neighborhood Hits	905	Target Neighborhood Hits	199	Shared Neighborhood Hits	100
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

IGF1R_MOUSE
θ value	0.125558 (rank : 660)	NC score	0.033218 (rank : 1017)
Query Neighborhood Hits	905	Target Neighborhood Hits	973	Shared Neighborhood Hits	143
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KRA59_HUMAN
θ value	0.125558 (rank : 661)	NC score	0.527343 (rank : 148)
Query Neighborhood Hits	905	Target Neighborhood Hits	310	Shared Neighborhood Hits	233
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA94_HUMAN
θ value	0.125558 (rank : 662)	NC score	0.367475 (rank : 432)
Query Neighborhood Hits	905	Target Neighborhood Hits	204	Shared Neighborhood Hits	170
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

ADA19_MOUSE
θ value	0.163984 (rank : 663)	NC score	0.169157 (rank : 667)
Query Neighborhood Hits	905	Target Neighborhood Hits	315	Shared Neighborhood Hits	205
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

CMTA2_HUMAN
θ value	0.163984 (rank : 664)	NC score	0.095986 (rank : 806)
Query Neighborhood Hits	905	Target Neighborhood Hits	199	Shared Neighborhood Hits	98
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CYR61_MOUSE
θ value	0.163984 (rank : 665)	NC score	0.098757 (rank : 796)
Query Neighborhood Hits	905	Target Neighborhood Hits	156	Shared Neighborhood Hits	82
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

EMR4_MOUSE
θ value	0.163984 (rank : 666)	NC score	0.217531 (rank : 597)
Query Neighborhood Hits	905	Target Neighborhood Hits	191	Shared Neighborhood Hits	121
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

EPHA1_HUMAN
θ value	0.163984 (rank : 667)	NC score	0.037179 (rank : 1012)
Query Neighborhood Hits	905	Target Neighborhood Hits	997	Shared Neighborhood Hits	134
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

LRP5_MOUSE
θ value	0.163984 (rank : 668)	NC score	0.239462 (rank : 574)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	170
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

MPRI_MOUSE
θ value	0.163984 (rank : 669)	NC score	0.023943 (rank : 1037)
Query Neighborhood Hits	905	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

NET1_HUMAN
θ value	0.163984 (rank : 670)	NC score	0.301278 (rank : 495)
Query Neighborhood Hits	905	Target Neighborhood Hits	149	Shared Neighborhood Hits	121
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

RING1_MOUSE
θ value	0.163984 (rank : 671)	NC score	0.010315 (rank : 1060)
Query Neighborhood Hits	905	Target Neighborhood Hits	220	Shared Neighborhood Hits	16
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TECTA_MOUSE
θ value	0.163984 (rank : 672)	NC score	0.218703 (rank : 595)
Query Neighborhood Hits	905	Target Neighborhood Hits	244	Shared Neighborhood Hits	200
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TLL2_MOUSE
θ value	0.163984 (rank : 673)	NC score	0.225065 (rank : 590)
Query Neighborhood Hits	905	Target Neighborhood Hits	240	Shared Neighborhood Hits	181
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

ANR32_HUMAN
θ value	0.21417 (rank : 674)	NC score	0.403776 (rank : 396)
Query Neighborhood Hits	905	Target Neighborhood Hits	270	Shared Neighborhood Hits	259
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ARMX2_HUMAN
θ value	0.21417 (rank : 675)	NC score	0.008436 (rank : 1066)
Query Neighborhood Hits	905	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

CLC14_MOUSE
θ value	0.21417 (rank : 676)	NC score	0.251383 (rank : 562)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	110
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CMTA2_MOUSE
θ value	0.21417 (rank : 677)	NC score	0.085621 (rank : 829)
Query Neighborhood Hits	905	Target Neighborhood Hits	216	Shared Neighborhood Hits	83
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

COGA1_HUMAN
θ value	0.21417 (rank : 678)	NC score	0.024088 (rank : 1036)
Query Neighborhood Hits	905	Target Neighborhood Hits	345	Shared Neighborhood Hits	46
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

IGF1R_HUMAN
θ value	0.21417 (rank : 679)	NC score	0.028885 (rank : 1025)
Query Neighborhood Hits	905	Target Neighborhood Hits	977	Shared Neighborhood Hits	142
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KR123_HUMAN
θ value	0.21417 (rank : 680)	NC score	0.100743 (rank : 792)
Query Neighborhood Hits	905	Target Neighborhood Hits	75	Shared Neighborhood Hits	56
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

KRA92_HUMAN
θ value	0.21417 (rank : 681)	NC score	0.341448 (rank : 468)
Query Neighborhood Hits	905	Target Neighborhood Hits	198	Shared Neighborhood Hits	157
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LCE1E_HUMAN
θ value	0.21417 (rank : 682)	NC score	0.286884 (rank : 515)
Query Neighborhood Hits	905	Target Neighborhood Hits	53	Shared Neighborhood Hits	35
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LRP10_MOUSE
θ value	0.21417 (rank : 683)	NC score	0.142861 (rank : 716)
Query Neighborhood Hits	905	Target Neighborhood Hits	169	Shared Neighborhood Hits	100
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

PCSK5_HUMAN
θ value	0.21417 (rank : 684)	NC score	0.223267 (rank : 591)
Query Neighborhood Hits	905	Target Neighborhood Hits	291	Shared Neighborhood Hits	189
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PGH1_MOUSE
θ value	0.21417 (rank : 685)	NC score	0.186858 (rank : 649)
Query Neighborhood Hits	905	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

RECK_HUMAN
θ value	0.21417 (rank : 686)	NC score	0.225635 (rank : 589)
Query Neighborhood Hits	905	Target Neighborhood Hits	189	Shared Neighborhood Hits	129
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

TLL1_HUMAN
θ value	0.21417 (rank : 687)	NC score	0.231605 (rank : 586)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	178
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TRPV2_MOUSE
θ value	0.21417 (rank : 688)	NC score	0.106639 (rank : 784)
Query Neighborhood Hits	905	Target Neighborhood Hits	111	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

VEGFC_MOUSE
θ value	0.21417 (rank : 689)	NC score	0.130464 (rank : 747)
Query Neighborhood Hits	905	Target Neighborhood Hits	119	Shared Neighborhood Hits	91
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ADA12_MOUSE
θ value	0.279714 (rank : 690)	NC score	0.122556 (rank : 761)
Query Neighborhood Hits	905	Target Neighborhood Hits	474	Shared Neighborhood Hits	148
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ANKR9_MOUSE
θ value	0.279714 (rank : 691)	NC score	0.170780 (rank : 666)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

APR3_HUMAN
θ value	0.279714 (rank : 692)	NC score	0.173576 (rank : 662)
Query Neighborhood Hits	905	Target Neighborhood Hits	50	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

CO9_MOUSE
θ value	0.279714 (rank : 693)	NC score	0.155877 (rank : 690)
Query Neighborhood Hits	905	Target Neighborhood Hits	153	Shared Neighborhood Hits	102
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

DDFL1_MOUSE
θ value	0.279714 (rank : 694)	NC score	0.253598 (rank : 557)
Query Neighborhood Hits	905	Target Neighborhood Hits	324	Shared Neighborhood Hits	249
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

FSTL3_HUMAN
θ value	0.279714 (rank : 695)	NC score	0.182014 (rank : 655)
Query Neighborhood Hits	905	Target Neighborhood Hits	162	Shared Neighborhood Hits	107
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

GP128_MOUSE
θ value	0.279714 (rank : 696)	NC score	0.101542 (rank : 789)
Query Neighborhood Hits	905	Target Neighborhood Hits	141	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

LCE1D_HUMAN
θ value	0.279714 (rank : 697)	NC score	0.296337 (rank : 501)
Query Neighborhood Hits	905	Target Neighborhood Hits	44	Shared Neighborhood Hits	31
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE2A_HUMAN
θ value	0.279714 (rank : 698)	NC score	0.155060 (rank : 692)
Query Neighborhood Hits	905	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LRP10_HUMAN
θ value	0.279714 (rank : 699)	NC score	0.144328 (rank : 713)
Query Neighborhood Hits	905	Target Neighborhood Hits	197	Shared Neighborhood Hits	103
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

MEP1B_HUMAN
θ value	0.279714 (rank : 700)	NC score	0.086032 (rank : 825)
Query Neighborhood Hits	905	Target Neighborhood Hits	98	Shared Neighborhood Hits	63
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1B_MOUSE
θ value	0.279714 (rank : 701)	NC score	0.132313 (rank : 744)
Query Neighborhood Hits	905	Target Neighborhood Hits	127	Shared Neighborhood Hits	91
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

TNR9_HUMAN
θ value	0.279714 (rank : 702)	NC score	0.113962 (rank : 772)
Query Neighborhood Hits	905	Target Neighborhood Hits	166	Shared Neighborhood Hits	88
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TYRP1_MOUSE
θ value	0.279714 (rank : 703)	NC score	0.043887 (rank : 1005)
Query Neighborhood Hits	905	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	P07147	Gene names	Tyrp1, Tyrp-1
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Brown locus protein).

AN13A_HUMAN
θ value	0.365318 (rank : 704)	NC score	0.245825 (rank : 567)
Query Neighborhood Hits	905	Target Neighborhood Hits	243	Shared Neighborhood Hits	216
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

CYR61_HUMAN
θ value	0.365318 (rank : 705)	NC score	0.095350 (rank : 807)
Query Neighborhood Hits	905	Target Neighborhood Hits	159	Shared Neighborhood Hits	84
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

EPHB2_HUMAN
θ value	0.365318 (rank : 706)	NC score	0.026475 (rank : 1029)
Query Neighborhood Hits	905	Target Neighborhood Hits	983	Shared Neighborhood Hits	98
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	0.365318 (rank : 707)	NC score	0.026189 (rank : 1031)
Query Neighborhood Hits	905	Target Neighborhood Hits	982	Shared Neighborhood Hits	98
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

ERBB3_MOUSE
θ value	0.365318 (rank : 708)	NC score	0.026483 (rank : 1028)
Query Neighborhood Hits	905	Target Neighborhood Hits	898	Shared Neighborhood Hits	109
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

EREG_HUMAN
θ value	0.365318 (rank : 709)	NC score	0.156834 (rank : 688)
Query Neighborhood Hits	905	Target Neighborhood Hits	73	Shared Neighborhood Hits	64
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

INSR_HUMAN
θ value	0.365318 (rank : 710)	NC score	0.032912 (rank : 1019)
Query Neighborhood Hits	905	Target Neighborhood Hits	963	Shared Neighborhood Hits	131
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

KR410_HUMAN
θ value	0.365318 (rank : 711)	NC score	0.261399 (rank : 547)
Query Neighborhood Hits	905	Target Neighborhood Hits	156	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KRA56_HUMAN
θ value	0.365318 (rank : 712)	NC score	0.434048 (rank : 338)
Query Neighborhood Hits	905	Target Neighborhood Hits	207	Shared Neighborhood Hits	169
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA98_HUMAN
θ value	0.365318 (rank : 713)	NC score	0.361654 (rank : 441)
Query Neighborhood Hits	905	Target Neighborhood Hits	185	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

NRG3_HUMAN
θ value	0.365318 (rank : 714)	NC score	0.093289 (rank : 812)
Query Neighborhood Hits	905	Target Neighborhood Hits	119	Shared Neighborhood Hits	69
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG3_MOUSE
θ value	0.365318 (rank : 715)	NC score	0.096522 (rank : 804)
Query Neighborhood Hits	905	Target Neighborhood Hits	132	Shared Neighborhood Hits	77
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG4_HUMAN
θ value	0.365318 (rank : 716)	NC score	0.213547 (rank : 603)
Query Neighborhood Hits	905	Target Neighborhood Hits	85	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

PAPPA_MOUSE
θ value	0.365318 (rank : 717)	NC score	0.107301 (rank : 783)
Query Neighborhood Hits	905	Target Neighborhood Hits	153	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

SMDF_HUMAN
θ value	0.365318 (rank : 718)	NC score	0.219323 (rank : 593)
Query Neighborhood Hits	905	Target Neighborhood Hits	117	Shared Neighborhood Hits	83
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

ST14_HUMAN
θ value	0.365318 (rank : 719)	NC score	0.158800 (rank : 686)
Query Neighborhood Hits	905	Target Neighborhood Hits	409	Shared Neighborhood Hits	194
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

AN13C_MOUSE
θ value	0.47712 (rank : 720)	NC score	0.256584 (rank : 552)
Query Neighborhood Hits	905	Target Neighborhood Hits	242	Shared Neighborhood Hits	232
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ESM1_HUMAN
θ value	0.47712 (rank : 721)	NC score	0.198608 (rank : 627)
Query Neighborhood Hits	905	Target Neighborhood Hits	110	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

GFRA3_MOUSE
θ value	0.47712 (rank : 722)	NC score	0.011870 (rank : 1053)
Query Neighborhood Hits	905	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

LCE3A_HUMAN
θ value	0.47712 (rank : 723)	NC score	0.204337 (rank : 618)
Query Neighborhood Hits	905	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LORI_MOUSE
θ value	0.47712 (rank : 724)	NC score	0.137579 (rank : 729)
Query Neighborhood Hits	905	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRP5_HUMAN
θ value	0.47712 (rank : 725)	NC score	0.231907 (rank : 585)
Query Neighborhood Hits	905	Target Neighborhood Hits	224	Shared Neighborhood Hits	166
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

MASP2_MOUSE
θ value	0.47712 (rank : 726)	NC score	0.128967 (rank : 751)
Query Neighborhood Hits	905	Target Neighborhood Hits	382	Shared Neighborhood Hits	163
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

NET1_MOUSE
θ value	0.47712 (rank : 727)	NC score	0.296803 (rank : 499)
Query Neighborhood Hits	905	Target Neighborhood Hits	151	Shared Neighborhood Hits	120
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NEU1_MOUSE
θ value	0.47712 (rank : 728)	NC score	0.083342 (rank : 838)
Query Neighborhood Hits	905	Target Neighborhood Hits	64	Shared Neighborhood Hits	56
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

SPY4_HUMAN
θ value	0.47712 (rank : 729)	NC score	0.034859 (rank : 1014)
Query Neighborhood Hits	905	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q9C004, Q6QIX2, Q9C003	Gene names	SPRY4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

TNR5_MOUSE
θ value	0.47712 (rank : 730)	NC score	0.085093 (rank : 831)
Query Neighborhood Hits	905	Target Neighborhood Hits	131	Shared Neighborhood Hits	72
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

AMER1_MOUSE
θ value	0.62314 (rank : 731)	NC score	0.011387 (rank : 1058)
Query Neighborhood Hits	905	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHT5	Gene names	Ammecr1
Domain Architecture
Description	AMME syndrome candidate gene 1 protein homolog.

ANKR9_HUMAN
θ value	0.62314 (rank : 732)	NC score	0.140283 (rank : 723)
Query Neighborhood Hits	905	Target Neighborhood Hits	99	Shared Neighborhood Hits	97
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

CRAC1_HUMAN
θ value	0.62314 (rank : 733)	NC score	0.279518 (rank : 530)
Query Neighborhood Hits	905	Target Neighborhood Hits	111	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	0.62314 (rank : 734)	NC score	0.280526 (rank : 527)
Query Neighborhood Hits	905	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CTG1B_HUMAN
θ value	0.62314 (rank : 735)	NC score	0.013281 (rank : 1051)
Query Neighborhood Hits	905	Target Neighborhood Hits	61	Shared Neighborhood Hits	10
SwissProt Accessions	P78358, Q7LBY4	Gene names	CTAG1B, CTAG, CTAG1, ESO1, LAGE2
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen 1B (L antigen family member 2) (LAGE-2 protein) (Autoimmunogenic cancer/testis antigen NY-ESO-1).

FST_MOUSE
θ value	0.62314 (rank : 736)	NC score	0.152590 (rank : 695)
Query Neighborhood Hits	905	Target Neighborhood Hits	146	Shared Neighborhood Hits	91
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

HYAL2_HUMAN
θ value	0.62314 (rank : 737)	NC score	0.023880 (rank : 1038)
Query Neighborhood Hits	905	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	Q12891, O15177, Q9BW29	Gene names	HYAL2, LUCA2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

NOV_HUMAN
θ value	0.62314 (rank : 738)	NC score	0.073292 (rank : 866)
Query Neighborhood Hits	905	Target Neighborhood Hits	128	Shared Neighborhood Hits	71
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

ADA23_MOUSE
θ value	0.813845 (rank : 739)	NC score	0.172628 (rank : 663)
Query Neighborhood Hits	905	Target Neighborhood Hits	245	Shared Neighborhood Hits	196
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

AKAP2_HUMAN
θ value	0.813845 (rank : 740)	NC score	0.011783 (rank : 1054)
Query Neighborhood Hits	905	Target Neighborhood Hits	507	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

AN13A_MOUSE
θ value	0.813845 (rank : 741)	NC score	0.230633 (rank : 587)
Query Neighborhood Hits	905	Target Neighborhood Hits	226	Shared Neighborhood Hits	215
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

CO9A3_HUMAN
θ value	0.813845 (rank : 742)	NC score	-0.000428 (rank : 1084)
Query Neighborhood Hits	905	Target Neighborhood Hits	361	Shared Neighborhood Hits	22
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CTGF_HUMAN
θ value	0.813845 (rank : 743)	NC score	0.089365 (rank : 819)
Query Neighborhood Hits	905	Target Neighborhood Hits	128	Shared Neighborhood Hits	68
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

KCNH4_HUMAN
θ value	0.813845 (rank : 744)	NC score	0.001172 (rank : 1080)
Query Neighborhood Hits	905	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KR122_HUMAN
θ value	0.813845 (rank : 745)	NC score	0.141425 (rank : 720)
Query Neighborhood Hits	905	Target Neighborhood Hits	97	Shared Neighborhood Hits	78
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KR171_HUMAN
θ value	0.813845 (rank : 746)	NC score	0.471196 (rank : 240)
Query Neighborhood Hits	905	Target Neighborhood Hits	144	Shared Neighborhood Hits	124
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

RING1_HUMAN
θ value	0.813845 (rank : 747)	NC score	0.007720 (rank : 1068)
Query Neighborhood Hits	905	Target Neighborhood Hits	219	Shared Neighborhood Hits	16
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

SPR1A_MOUSE
θ value	0.813845 (rank : 748)	NC score	0.014122 (rank : 1048)
Query Neighborhood Hits	905	Target Neighborhood Hits	343	Shared Neighborhood Hits	37
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SPY3_HUMAN
θ value	0.813845 (rank : 749)	NC score	0.038107 (rank : 1011)
Query Neighborhood Hits	905	Target Neighborhood Hits	48	Shared Neighborhood Hits	31
SwissProt Accessions	O43610	Gene names	SPRY3
Domain Architecture
Description	Sprouty homolog 3 (Spry-3).

SPY4_MOUSE
θ value	0.813845 (rank : 750)	NC score	0.048649 (rank : 995)
Query Neighborhood Hits	905	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

WISP1_MOUSE
θ value	0.813845 (rank : 751)	NC score	0.064537 (rank : 898)
Query Neighborhood Hits	905	Target Neighborhood Hits	123	Shared Neighborhood Hits	57
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

ADA28_MOUSE
θ value	1.06291 (rank : 752)	NC score	0.134893 (rank : 739)
Query Neighborhood Hits	905	Target Neighborhood Hits	241	Shared Neighborhood Hits	172
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA32_MOUSE
θ value	1.06291 (rank : 753)	NC score	0.124797 (rank : 758)
Query Neighborhood Hits	905	Target Neighborhood Hits	219	Shared Neighborhood Hits	172
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ANR45_HUMAN
θ value	1.06291 (rank : 754)	NC score	0.275383 (rank : 533)
Query Neighborhood Hits	905	Target Neighborhood Hits	201	Shared Neighborhood Hits	183
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ATL2_MOUSE
θ value	1.06291 (rank : 755)	NC score	0.031297 (rank : 1021)
Query Neighborhood Hits	905	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

C1R_HUMAN
θ value	1.06291 (rank : 756)	NC score	0.136773 (rank : 732)
Query Neighborhood Hits	905	Target Neighborhood Hits	364	Shared Neighborhood Hits	161
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

IER5_MOUSE
θ value	1.06291 (rank : 757)	NC score	0.019656 (rank : 1043)
Query Neighborhood Hits	905	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

LRP12_MOUSE
θ value	1.06291 (rank : 758)	NC score	0.135333 (rank : 737)
Query Neighborhood Hits	905	Target Neighborhood Hits	180	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LYPD1_MOUSE
θ value	1.06291 (rank : 759)	NC score	0.046920 (rank : 998)
Query Neighborhood Hits	905	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BLC3, Q3V2X5, Q3V447, Q9JJ96	Gene names	Lypd1, Lypdc1
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 1 precursor.

PRR13_MOUSE
θ value	1.06291 (rank : 760)	NC score	0.031139 (rank : 1022)
Query Neighborhood Hits	905	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

TACC3_HUMAN
θ value	1.06291 (rank : 761)	NC score	0.020463 (rank : 1041)
Query Neighborhood Hits	905	Target Neighborhood Hits	779	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TECTA_HUMAN
θ value	1.06291 (rank : 762)	NC score	0.196853 (rank : 629)
Query Neighborhood Hits	905	Target Neighborhood Hits	239	Shared Neighborhood Hits	191
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TRPC6_HUMAN
θ value	1.06291 (rank : 763)	NC score	0.055886 (rank : 953)
Query Neighborhood Hits	905	Target Neighborhood Hits	171	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPV1_MOUSE
θ value	1.06291 (rank : 764)	NC score	0.147081 (rank : 705)
Query Neighborhood Hits	905	Target Neighborhood Hits	189	Shared Neighborhood Hits	153
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

ADA22_HUMAN
θ value	1.38821 (rank : 765)	NC score	0.132851 (rank : 741)
Query Neighborhood Hits	905	Target Neighborhood Hits	211	Shared Neighborhood Hits	146
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADAM2_MOUSE
θ value	1.38821 (rank : 766)	NC score	0.146520 (rank : 708)
Query Neighborhood Hits	905	Target Neighborhood Hits	209	Shared Neighborhood Hits	162
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADM1A_MOUSE
θ value	1.38821 (rank : 767)	NC score	0.139426 (rank : 726)
Query Neighborhood Hits	905	Target Neighborhood Hits	230	Shared Neighborhood Hits	187
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

FIBA_HUMAN
θ value	1.38821 (rank : 768)	NC score	0.049149 (rank : 993)
Query Neighborhood Hits	905	Target Neighborhood Hits	132	Shared Neighborhood Hits	16
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

LYPD1_HUMAN
θ value	1.38821 (rank : 769)	NC score	0.045675 (rank : 1001)
Query Neighborhood Hits	905	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N2G4, Q96AC2	Gene names	LYPD1, LYPDC1
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 1 precursor.

MLL3_MOUSE
θ value	1.38821 (rank : 770)	NC score	0.042072 (rank : 1006)
Query Neighborhood Hits	905	Target Neighborhood Hits	1399	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MPRI_HUMAN
θ value	1.38821 (rank : 771)	NC score	0.020037 (rank : 1042)
Query Neighborhood Hits	905	Target Neighborhood Hits	67	Shared Neighborhood Hits	9
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

PGH1_HUMAN
θ value	1.38821 (rank : 772)	NC score	0.161264 (rank : 674)
Query Neighborhood Hits	905	Target Neighborhood Hits	91	Shared Neighborhood Hits	78
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

RSPO3_MOUSE
θ value	1.38821 (rank : 773)	NC score	0.097662 (rank : 800)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	72
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

TNR5_HUMAN
θ value	1.38821 (rank : 774)	NC score	0.058185 (rank : 941)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

VEGFC_HUMAN
θ value	1.38821 (rank : 775)	NC score	0.148554 (rank : 702)
Query Neighborhood Hits	905	Target Neighborhood Hits	128	Shared Neighborhood Hits	104
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CO8A_HUMAN
θ value	1.81305 (rank : 776)	NC score	0.136134 (rank : 733)
Query Neighborhood Hits	905	Target Neighborhood Hits	200	Shared Neighborhood Hits	110
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

DKK3_MOUSE
θ value	1.81305 (rank : 777)	NC score	0.102567 (rank : 787)
Query Neighborhood Hits	905	Target Neighborhood Hits	83	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

IMPG1_HUMAN
θ value	1.81305 (rank : 778)	NC score	0.044241 (rank : 1004)
Query Neighborhood Hits	905	Target Neighborhood Hits	75	Shared Neighborhood Hits	26
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

KR413_HUMAN
θ value	1.81305 (rank : 779)	NC score	0.208487 (rank : 611)
Query Neighborhood Hits	905	Target Neighborhood Hits	112	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

LCE1F_HUMAN
θ value	1.81305 (rank : 780)	NC score	0.254015 (rank : 556)
Query Neighborhood Hits	905	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

MKS3_HUMAN
θ value	1.81305 (rank : 781)	NC score	0.135033 (rank : 738)
Query Neighborhood Hits	905	Target Neighborhood Hits	79	Shared Neighborhood Hits	73
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

MKS3_MOUSE
θ value	1.81305 (rank : 782)	NC score	0.140693 (rank : 722)
Query Neighborhood Hits	905	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

SPR1B_MOUSE
θ value	1.81305 (rank : 783)	NC score	0.014844 (rank : 1045)
Query Neighborhood Hits	905	Target Neighborhood Hits	395	Shared Neighborhood Hits	43
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

U6126_HUMAN
θ value	1.81305 (rank : 784)	NC score	0.014328 (rank : 1047)
Query Neighborhood Hits	905	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UXV3	Gene names	ames=UNQ6126/PRO20091
Domain Architecture	No domain graphic available
Description	Protein UNQ6126/PRO20091 precursor.

ADA29_HUMAN
θ value	2.36792 (rank : 785)	NC score	0.112239 (rank : 775)
Query Neighborhood Hits	905	Target Neighborhood Hits	247	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADAM7_HUMAN
θ value	2.36792 (rank : 786)	NC score	0.144548 (rank : 711)
Query Neighborhood Hits	905	Target Neighborhood Hits	221	Shared Neighborhood Hits	171
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ATS9_HUMAN
θ value	2.36792 (rank : 787)	NC score	0.056734 (rank : 947)
Query Neighborhood Hits	905	Target Neighborhood Hits	219	Shared Neighborhood Hits	120
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

DGKQ_HUMAN
θ value	2.36792 (rank : 788)	NC score	0.009328 (rank : 1062)
Query Neighborhood Hits	905	Target Neighborhood Hits	131	Shared Neighborhood Hits	16
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

LRP12_HUMAN
θ value	2.36792 (rank : 789)	NC score	0.135999 (rank : 734)
Query Neighborhood Hits	905	Target Neighborhood Hits	205	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

MBD6_HUMAN
θ value	2.36792 (rank : 790)	NC score	0.024211 (rank : 1035)
Query Neighborhood Hits	905	Target Neighborhood Hits	349	Shared Neighborhood Hits	33
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

TNR1B_MOUSE
θ value	2.36792 (rank : 791)	NC score	0.040494 (rank : 1007)
Query Neighborhood Hits	905	Target Neighborhood Hits	123	Shared Neighborhood Hits	48
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TYPH_MOUSE
θ value	2.36792 (rank : 792)	NC score	0.013024 (rank : 1052)
Query Neighborhood Hits	905	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q99N42	Gene names	Ecgf1
Domain Architecture
Description	Thymidine phosphorylase (EC 2.4.2.4) (TdRPase) (TP).

WNT9A_HUMAN
θ value	2.36792 (rank : 793)	NC score	0.001694 (rank : 1079)
Query Neighborhood Hits	905	Target Neighborhood Hits	52	Shared Neighborhood Hits	9
SwissProt Accessions	O14904, Q5VWU0, Q96S50	Gene names	WNT9A, WNT14
Domain Architecture
Description	Protein Wnt-9a precursor (Wnt-14).

ADA20_HUMAN
θ value	3.0926 (rank : 794)	NC score	0.089964 (rank : 817)
Query Neighborhood Hits	905	Target Neighborhood Hits	143	Shared Neighborhood Hits	95
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA21_HUMAN
θ value	3.0926 (rank : 795)	NC score	0.127191 (rank : 755)
Query Neighborhood Hits	905	Target Neighborhood Hits	181	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ASB14_HUMAN
θ value	3.0926 (rank : 796)	NC score	0.304497 (rank : 492)
Query Neighborhood Hits	905	Target Neighborhood Hits	187	Shared Neighborhood Hits	172
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

BAI2_MOUSE
θ value	3.0926 (rank : 797)	NC score	0.085840 (rank : 827)
Query Neighborhood Hits	905	Target Neighborhood Hits	323	Shared Neighborhood Hits	76
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAMBI_MOUSE
θ value	3.0926 (rank : 798)	NC score	0.009378 (rank : 1061)
Query Neighborhood Hits	905	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D0L6, Q3TP85, Q91XS6	Gene names	Bambi, Nma
Domain Architecture	No domain graphic available
Description	BMP and activin membrane-bound inhibitor homolog precursor (Putative transmembrane protein NMA).

BC11A_HUMAN
θ value	3.0926 (rank : 799)	NC score	-0.019621 (rank : 1095)
Query Neighborhood Hits	905	Target Neighborhood Hits	745	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H165, Q86W14, Q8WU92, Q96JL6, Q9H163, Q9H164, Q9H3G9, Q9NWA7	Gene names	BCL11A, CTIP1, EVI9, KIAA1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

BC11A_MOUSE
θ value	3.0926 (rank : 800)	NC score	-0.018666 (rank : 1094)
Query Neighborhood Hits	905	Target Neighborhood Hits	732	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYE3, Q80T89, Q8BLC7, Q8BLR4, Q8BWX3, Q921V4, Q9D0V2, Q9JIT4, Q9JLK8, Q9JLK9	Gene names	Bcl11a, Ctip1, Evi9, Kiaa1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

CO4A6_HUMAN
θ value	3.0926 (rank : 801)	NC score	0.000687 (rank : 1082)
Query Neighborhood Hits	905	Target Neighborhood Hits	318	Shared Neighborhood Hits	24
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

DDFL1_HUMAN
θ value	3.0926 (rank : 802)	NC score	0.199176 (rank : 625)
Query Neighborhood Hits	905	Target Neighborhood Hits	353	Shared Neighborhood Hits	232
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DKK3_HUMAN
θ value	3.0926 (rank : 803)	NC score	0.092455 (rank : 814)
Query Neighborhood Hits	905	Target Neighborhood Hits	74	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

FOXN1_HUMAN
θ value	3.0926 (rank : 804)	NC score	-0.002469 (rank : 1086)
Query Neighborhood Hits	905	Target Neighborhood Hits	377	Shared Neighborhood Hits	23
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

GP128_HUMAN
θ value	3.0926 (rank : 805)	NC score	0.094687 (rank : 808)
Query Neighborhood Hits	905	Target Neighborhood Hits	135	Shared Neighborhood Hits	52
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

HYAL3_MOUSE
θ value	3.0926 (rank : 806)	NC score	0.048866 (rank : 994)
Query Neighborhood Hits	905	Target Neighborhood Hits	44	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

LTK_MOUSE
θ value	3.0926 (rank : 807)	NC score	0.008624 (rank : 1065)
Query Neighborhood Hits	905	Target Neighborhood Hits	770	Shared Neighborhood Hits	39
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

MLL3_HUMAN
θ value	3.0926 (rank : 808)	NC score	0.039176 (rank : 1010)
Query Neighborhood Hits	905	Target Neighborhood Hits	1644	Shared Neighborhood Hits	128
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MT4_MOUSE
θ value	3.0926 (rank : 809)	NC score	0.166834 (rank : 670)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	74
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_HUMAN
θ value	3.0926 (rank : 810)	NC score	0.184383 (rank : 653)
Query Neighborhood Hits	905	Target Neighborhood Hits	164	Shared Neighborhood Hits	101
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

NCOA6_MOUSE
θ value	3.0926 (rank : 811)	NC score	0.028699 (rank : 1026)
Query Neighborhood Hits	905	Target Neighborhood Hits	1076	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

RECK_MOUSE
θ value	3.0926 (rank : 812)	NC score	0.186737 (rank : 650)
Query Neighborhood Hits	905	Target Neighborhood Hits	158	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TNR14_HUMAN
θ value	3.0926 (rank : 813)	NC score	0.108158 (rank : 780)
Query Neighborhood Hits	905	Target Neighborhood Hits	149	Shared Neighborhood Hits	87
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TYRP1_HUMAN
θ value	3.0926 (rank : 814)	NC score	0.040403 (rank : 1008)
Query Neighborhood Hits	905	Target Neighborhood Hits	40	Shared Neighborhood Hits	32
SwissProt Accessions	P17643, P78468, P78469, Q13721, Q15679	Gene names	TYRP1, CAS2, TYRP, TYRRP
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75).

BAT4_MOUSE
θ value	4.03905 (rank : 815)	NC score	0.139818 (rank : 725)
Query Neighborhood Hits	905	Target Neighborhood Hits	171	Shared Neighborhood Hits	120
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CO6A1_HUMAN
θ value	4.03905 (rank : 816)	NC score	0.014082 (rank : 1049)
Query Neighborhood Hits	905	Target Neighborhood Hits	264	Shared Neighborhood Hits	25
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

ICAM5_MOUSE
θ value	4.03905 (rank : 817)	NC score	0.011724 (rank : 1055)
Query Neighborhood Hits	905	Target Neighborhood Hits	308	Shared Neighborhood Hits	12
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

KRHB5_HUMAN
θ value	4.03905 (rank : 818)	NC score	-0.004185 (rank : 1088)
Query Neighborhood Hits	905	Target Neighborhood Hits	321	Shared Neighborhood Hits	15
SwissProt Accessions	P78386, Q9NSB1	Gene names	KRTHB5
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

LTK_HUMAN
θ value	4.03905 (rank : 819)	NC score	0.008957 (rank : 1064)
Query Neighborhood Hits	905	Target Neighborhood Hits	774	Shared Neighborhood Hits	39
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

MMRN2_HUMAN
θ value	4.03905 (rank : 820)	NC score	0.026358 (rank : 1030)
Query Neighborhood Hits	905	Target Neighborhood Hits	400	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

NUD12_MOUSE
θ value	4.03905 (rank : 821)	NC score	0.277234 (rank : 532)
Query Neighborhood Hits	905	Target Neighborhood Hits	243	Shared Neighborhood Hits	220
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

SPEG_HUMAN
θ value	4.03905 (rank : 822)	NC score	0.000788 (rank : 1081)
Query Neighborhood Hits	905	Target Neighborhood Hits	1762	Shared Neighborhood Hits	85
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPY1_HUMAN
θ value	4.03905 (rank : 823)	NC score	0.048555 (rank : 996)
Query Neighborhood Hits	905	Target Neighborhood Hits	64	Shared Neighborhood Hits	49
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

SPY1_MOUSE
θ value	4.03905 (rank : 824)	NC score	0.046913 (rank : 999)
Query Neighborhood Hits	905	Target Neighborhood Hits	57	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

WISP2_MOUSE
θ value	4.03905 (rank : 825)	NC score	0.067512 (rank : 889)
Query Neighborhood Hits	905	Target Neighborhood Hits	129	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

WNT9A_MOUSE
θ value	4.03905 (rank : 826)	NC score	0.000618 (rank : 1083)
Query Neighborhood Hits	905	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R5M2	Gene names	Wnt9a, Wnt14
Domain Architecture
Description	Protein Wnt-9a precursor (Wnt-14).

ZN446_HUMAN
θ value	4.03905 (rank : 827)	NC score	-0.018038 (rank : 1093)
Query Neighborhood Hits	905	Target Neighborhood Hits	721	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NWS9	Gene names	ZNF446
Domain Architecture	No domain graphic available
Description	Zinc finger protein 446.

ABTB1_MOUSE
θ value	5.27518 (rank : 828)	NC score	0.141142 (rank : 721)
Query Neighborhood Hits	905	Target Neighborhood Hits	349	Shared Neighborhood Hits	175
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ADA17_HUMAN
θ value	5.27518 (rank : 829)	NC score	0.146546 (rank : 707)
Query Neighborhood Hits	905	Target Neighborhood Hits	223	Shared Neighborhood Hits	154
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ASTN_MOUSE
θ value	5.27518 (rank : 830)	NC score	0.147496 (rank : 703)
Query Neighborhood Hits	905	Target Neighborhood Hits	98	Shared Neighborhood Hits	78
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATL2_HUMAN
θ value	5.27518 (rank : 831)	NC score	0.036606 (rank : 1013)
Query Neighborhood Hits	905	Target Neighborhood Hits	125	Shared Neighborhood Hits	49
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

BAI2_HUMAN
θ value	5.27518 (rank : 832)	NC score	0.084335 (rank : 833)
Query Neighborhood Hits	905	Target Neighborhood Hits	332	Shared Neighborhood Hits	74
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BTC_MOUSE
θ value	5.27518 (rank : 833)	NC score	0.114275 (rank : 771)
Query Neighborhood Hits	905	Target Neighborhood Hits	67	Shared Neighborhood Hits	59
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

COIA1_MOUSE
θ value	5.27518 (rank : 834)	NC score	0.003508 (rank : 1075)
Query Neighborhood Hits	905	Target Neighborhood Hits	481	Shared Neighborhood Hits	37
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CTGF_MOUSE
θ value	5.27518 (rank : 835)	NC score	0.083955 (rank : 835)
Query Neighborhood Hits	905	Target Neighborhood Hits	124	Shared Neighborhood Hits	66
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

ENPP2_HUMAN
θ value	5.27518 (rank : 836)	NC score	0.024685 (rank : 1033)
Query Neighborhood Hits	905	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

FST_HUMAN
θ value	5.27518 (rank : 837)	NC score	0.137449 (rank : 730)
Query Neighborhood Hits	905	Target Neighborhood Hits	129	Shared Neighborhood Hits	73
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

HBEGF_MOUSE
θ value	5.27518 (rank : 838)	NC score	0.072311 (rank : 869)
Query Neighborhood Hits	905	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

HEM6_HUMAN
θ value	5.27518 (rank : 839)	NC score	0.004053 (rank : 1073)
Query Neighborhood Hits	905	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P36551, Q14060, Q8IZ45, Q96AF3	Gene names	CPOX, CPO, CPX
Domain Architecture
Description	Coproporphyrinogen III oxidase, mitochondrial precursor (EC 1.3.3.3) (Coproporphyrinogenase) (Coprogen oxidase) (COX).

INSRR_MOUSE
θ value	5.27518 (rank : 840)	NC score	0.046277 (rank : 1000)
Query Neighborhood Hits	905	Target Neighborhood Hits	961	Shared Neighborhood Hits	142
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

KR261_HUMAN
θ value	5.27518 (rank : 841)	NC score	0.082864 (rank : 839)
Query Neighborhood Hits	905	Target Neighborhood Hits	65	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

LCE1A_HUMAN
θ value	5.27518 (rank : 842)	NC score	0.244465 (rank : 569)
Query Neighborhood Hits	905	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE2D_HUMAN
θ value	5.27518 (rank : 843)	NC score	0.151037 (rank : 699)
Query Neighborhood Hits	905	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

MARH2_HUMAN
θ value	5.27518 (rank : 844)	NC score	0.002355 (rank : 1077)
Query Neighborhood Hits	905	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P0N8, Q8N5A3, Q96B78	Gene names	MARCH2, RNF172
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 2 (Membrane-associated RING-CH protein II) (MARCH-II) (RING finger protein 172).

MASP1_HUMAN
θ value	5.27518 (rank : 845)	NC score	0.121676 (rank : 762)
Query Neighborhood Hits	905	Target Neighborhood Hits	369	Shared Neighborhood Hits	157
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	5.27518 (rank : 846)	NC score	0.119482 (rank : 766)
Query Neighborhood Hits	905	Target Neighborhood Hits	364	Shared Neighborhood Hits	158
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

N2DL3_HUMAN
θ value	5.27518 (rank : 847)	NC score	-0.005315 (rank : 1090)
Query Neighborhood Hits	905	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZM4, Q8IZX5, Q8TE75	Gene names	ULBP3, N2DL3, RAET1N
Domain Architecture
Description	NKG2D ligand 3 precursor (NKG2D ligand 3) (NKG2DL3) (N2DL-3) (ALCAN- gamma) (Retinoic acid early transcript 1N).

NOV_MOUSE
θ value	5.27518 (rank : 848)	NC score	0.063917 (rank : 908)
Query Neighborhood Hits	905	Target Neighborhood Hits	130	Shared Neighborhood Hits	69
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

RSPO4_HUMAN
θ value	5.27518 (rank : 849)	NC score	0.088454 (rank : 821)
Query Neighborhood Hits	905	Target Neighborhood Hits	110	Shared Neighborhood Hits	76
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SPR2K_MOUSE
θ value	5.27518 (rank : 850)	NC score	0.034776 (rank : 1015)
Query Neighborhood Hits	905	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	O70562	Gene names	Sprr2k
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2K.

TR10B_MOUSE
θ value	5.27518 (rank : 851)	NC score	0.045224 (rank : 1003)
Query Neighborhood Hits	905	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TRPV1_HUMAN
θ value	5.27518 (rank : 852)	NC score	0.143839 (rank : 715)
Query Neighborhood Hits	905	Target Neighborhood Hits	184	Shared Neighborhood Hits	145
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

UBP51_HUMAN
θ value	5.27518 (rank : 853)	NC score	-0.002719 (rank : 1087)
Query Neighborhood Hits	905	Target Neighborhood Hits	162	Shared Neighborhood Hits	13
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

AD26A_MOUSE
θ value	6.88961 (rank : 854)	NC score	0.099010 (rank : 795)
Query Neighborhood Hits	905	Target Neighborhood Hits	165	Shared Neighborhood Hits	122
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA22_MOUSE
θ value	6.88961 (rank : 855)	NC score	0.141654 (rank : 719)
Query Neighborhood Hits	905	Target Neighborhood Hits	225	Shared Neighborhood Hits	156
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ANR45_MOUSE
θ value	6.88961 (rank : 856)	NC score	0.290118 (rank : 509)
Query Neighborhood Hits	905	Target Neighborhood Hits	204	Shared Neighborhood Hits	188
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

BTC_HUMAN
θ value	6.88961 (rank : 857)	NC score	0.100281 (rank : 793)
Query Neighborhood Hits	905	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

C1S_HUMAN
θ value	6.88961 (rank : 858)	NC score	0.124775 (rank : 759)
Query Neighborhood Hits	905	Target Neighborhood Hits	359	Shared Neighborhood Hits	158
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CFAH_MOUSE
θ value	6.88961 (rank : 859)	NC score	0.032942 (rank : 1018)
Query Neighborhood Hits	905	Target Neighborhood Hits	112	Shared Neighborhood Hits	41
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

CLC14_HUMAN
θ value	6.88961 (rank : 860)	NC score	0.236242 (rank : 581)
Query Neighborhood Hits	905	Target Neighborhood Hits	143	Shared Neighborhood Hits	113
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CO7A1_HUMAN
θ value	6.88961 (rank : 861)	NC score	0.054438 (rank : 962)
Query Neighborhood Hits	905	Target Neighborhood Hits	807	Shared Neighborhood Hits	89
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO9_HUMAN
θ value	6.88961 (rank : 862)	NC score	0.141865 (rank : 717)
Query Neighborhood Hits	905	Target Neighborhood Hits	147	Shared Neighborhood Hits	98
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

COBA1_HUMAN
θ value	6.88961 (rank : 863)	NC score	0.007428 (rank : 1069)
Query Neighborhood Hits	905	Target Neighborhood Hits	491	Shared Neighborhood Hits	38
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	6.88961 (rank : 864)	NC score	0.008958 (rank : 1063)
Query Neighborhood Hits	905	Target Neighborhood Hits	487	Shared Neighborhood Hits	40
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COHA1_MOUSE
θ value	6.88961 (rank : 865)	NC score	0.002938 (rank : 1076)
Query Neighborhood Hits	905	Target Neighborhood Hits	414	Shared Neighborhood Hits	28
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CS1B_MOUSE
θ value	6.88961 (rank : 866)	NC score	0.129173 (rank : 749)
Query Neighborhood Hits	905	Target Neighborhood Hits	361	Shared Neighborhood Hits	152
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CT012_HUMAN
θ value	6.88961 (rank : 867)	NC score	0.210043 (rank : 608)
Query Neighborhood Hits	905	Target Neighborhood Hits	205	Shared Neighborhood Hits	179
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

CU024_HUMAN
θ value	6.88961 (rank : 868)	NC score	0.008311 (rank : 1067)
Query Neighborhood Hits	905	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q6XXX2	Gene names	C21orf24
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf24.

EDNRB_MOUSE
θ value	6.88961 (rank : 869)	NC score	-0.016410 (rank : 1092)
Query Neighborhood Hits	905	Target Neighborhood Hits	587	Shared Neighborhood Hits	2
SwissProt Accessions	P48302, Q542M3	Gene names	Ednrb
Domain Architecture
Description	Endothelin B receptor precursor (ET-B) (Endothelin receptor Non- selective type).

EPGN_MOUSE
θ value	6.88961 (rank : 870)	NC score	0.125155 (rank : 757)
Query Neighborhood Hits	905	Target Neighborhood Hits	63	Shared Neighborhood Hits	56
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

FSTL4_HUMAN
θ value	6.88961 (rank : 871)	NC score	0.014430 (rank : 1046)
Query Neighborhood Hits	905	Target Neighborhood Hits	344	Shared Neighborhood Hits	28
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

HAIR_HUMAN
θ value	6.88961 (rank : 872)	NC score	0.006658 (rank : 1072)
Query Neighborhood Hits	905	Target Neighborhood Hits	172	Shared Neighborhood Hits	19
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

HBEGF_HUMAN
θ value	6.88961 (rank : 873)	NC score	0.099508 (rank : 794)
Query Neighborhood Hits	905	Target Neighborhood Hits	61	Shared Neighborhood Hits	53
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

INSRR_HUMAN
θ value	6.88961 (rank : 874)	NC score	0.045490 (rank : 1002)
Query Neighborhood Hits	905	Target Neighborhood Hits	950	Shared Neighborhood Hits	134
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

LCE2B_HUMAN
θ value	6.88961 (rank : 875)	NC score	0.146499 (rank : 709)
Query Neighborhood Hits	905	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE3C_HUMAN
θ value	6.88961 (rank : 876)	NC score	0.077561 (rank : 856)
Query Neighborhood Hits	905	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

MATN1_HUMAN
θ value	6.88961 (rank : 877)	NC score	0.196589 (rank : 630)
Query Neighborhood Hits	905	Target Neighborhood Hits	191	Shared Neighborhood Hits	141
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MEFV_MOUSE
θ value	6.88961 (rank : 878)	NC score	0.002209 (rank : 1078)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

PO4F2_MOUSE
θ value	6.88961 (rank : 879)	NC score	-0.007381 (rank : 1091)
Query Neighborhood Hits	905	Target Neighborhood Hits	312	Shared Neighborhood Hits	3
SwissProt Accessions	Q63934, Q63954	Gene names	Pou4f2, Brn3b
Domain Architecture
Description	POU domain, class 4, transcription factor 2 (Brain-specific homeobox/POU domain protein 3B) (Brn-3B) (Brn-3.2).

RSPO3_HUMAN
θ value	6.88961 (rank : 880)	NC score	0.109954 (rank : 777)
Query Neighborhood Hits	905	Target Neighborhood Hits	128	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

SDK1_HUMAN
θ value	6.88961 (rank : 881)	NC score	0.032807 (rank : 1020)
Query Neighborhood Hits	905	Target Neighborhood Hits	511	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SPR2E_MOUSE
θ value	6.88961 (rank : 882)	NC score	0.058586 (rank : 939)
Query Neighborhood Hits	905	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2I_MOUSE
θ value	6.88961 (rank : 883)	NC score	0.068070 (rank : 884)
Query Neighborhood Hits	905	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

SYN1_HUMAN
θ value	6.88961 (rank : 884)	NC score	0.013788 (rank : 1050)
Query Neighborhood Hits	905	Target Neighborhood Hits	419	Shared Neighborhood Hits	37
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TRI65_HUMAN
θ value	6.88961 (rank : 885)	NC score	-0.005170 (rank : 1089)
Query Neighborhood Hits	905	Target Neighborhood Hits	330	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

UBP38_HUMAN
θ value	6.88961 (rank : 886)	NC score	-0.001651 (rank : 1085)
Query Neighborhood Hits	905	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

BAT4_HUMAN
θ value	8.99809 (rank : 887)	NC score	0.118123 (rank : 769)
Query Neighborhood Hits	905	Target Neighborhood Hits	157	Shared Neighborhood Hits	111
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CS1A_MOUSE
θ value	8.99809 (rank : 888)	NC score	0.130083 (rank : 748)
Query Neighborhood Hits	905	Target Neighborhood Hits	360	Shared Neighborhood Hits	152
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CT012_MOUSE
θ value	8.99809 (rank : 889)	NC score	0.237527 (rank : 578)
Query Neighborhood Hits	905	Target Neighborhood Hits	229	Shared Neighborhood Hits	187
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

ENPP2_MOUSE
θ value	8.99809 (rank : 890)	NC score	0.030671 (rank : 1023)
Query Neighborhood Hits	905	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

EPHB6_HUMAN
θ value	8.99809 (rank : 891)	NC score	0.034231 (rank : 1016)
Query Neighborhood Hits	905	Target Neighborhood Hits	912	Shared Neighborhood Hits	113
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

HGS_MOUSE
θ value	8.99809 (rank : 892)	NC score	0.003663 (rank : 1074)
Query Neighborhood Hits	905	Target Neighborhood Hits	589	Shared Neighborhood Hits	21
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HYAL1_HUMAN
θ value	8.99809 (rank : 893)	NC score	0.011557 (rank : 1056)
Query Neighborhood Hits	905	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q12794, Q6FH23, Q6PIZ6, Q7KYU2, Q7LE34, Q8NFK5, Q8NFK6, Q8NFK7, Q8NFK8, Q8NFK9, Q93013, Q9UKD5, Q9UNI8	Gene names	HYAL1, LUCA1
Domain Architecture	No domain graphic available
Description	Hyaluronidase-1 precursor (EC 3.2.1.35) (Hyal-1) (Hyaluronoglucosaminidase-1) (LUCA-1).

HYAL1_MOUSE
θ value	8.99809 (rank : 894)	NC score	0.010525 (rank : 1059)
Query Neighborhood Hits	905	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZJ9, O70229, Q8CE62, Q8QZX3, Q8VBW7, Q8VDK0	Gene names	Hyal1
Domain Architecture	No domain graphic available
Description	Hyaluronidase-1 precursor (EC 3.2.1.35) (Hyal-1) (Hyaluronoglucosaminidase-1).

IRS2_HUMAN
θ value	8.99809 (rank : 895)	NC score	0.006912 (rank : 1070)
Query Neighborhood Hits	905	Target Neighborhood Hits	262	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

LORI_HUMAN
θ value	8.99809 (rank : 896)	NC score	0.047626 (rank : 997)
Query Neighborhood Hits	905	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	P23490	Gene names	LOR, LRN
Domain Architecture	No domain graphic available
Description	Loricrin.

MGAT3_HUMAN
θ value	8.99809 (rank : 897)	NC score	0.024355 (rank : 1034)
Query Neighborhood Hits	905	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	Q09327, Q6IC49, Q9UH32	Gene names	MGAT3, GGNT3
Domain Architecture
Description	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase III) (N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III).

MGAT3_MOUSE
θ value	8.99809 (rank : 898)	NC score	0.022431 (rank : 1039)
Query Neighborhood Hits	905	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	Q10470, P70386	Gene names	Mgat3
Domain Architecture
Description	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase III) (N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III).

MNT_HUMAN
θ value	8.99809 (rank : 899)	NC score	0.011412 (rank : 1057)
Query Neighborhood Hits	905	Target Neighborhood Hits	496	Shared Neighborhood Hits	32
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MT4_HUMAN
θ value	8.99809 (rank : 900)	NC score	0.127483 (rank : 754)
Query Neighborhood Hits	905	Target Neighborhood Hits	83	Shared Neighborhood Hits	57
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

NUD12_HUMAN
θ value	8.99809 (rank : 901)	NC score	0.255195 (rank : 555)
Query Neighborhood Hits	905	Target Neighborhood Hits	222	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

PRR13_HUMAN
θ value	8.99809 (rank : 902)	NC score	0.022070 (rank : 1040)
Query Neighborhood Hits	905	Target Neighborhood Hits	105	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RSNL2_HUMAN
θ value	8.99809 (rank : 903)	NC score	0.120290 (rank : 765)
Query Neighborhood Hits	905	Target Neighborhood Hits	136	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TGFA_HUMAN
θ value	8.99809 (rank : 904)	NC score	0.092560 (rank : 813)
Query Neighborhood Hits	905	Target Neighborhood Hits	61	Shared Neighborhood Hits	55
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TNR4_HUMAN
θ value	8.99809 (rank : 905)	NC score	0.097439 (rank : 802)
Query Neighborhood Hits	905	Target Neighborhood Hits	152	Shared Neighborhood Hits	74
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

ABTB1_HUMAN
θ value	θ > 10 (rank : 906)	NC score	0.121377 (rank : 764)
Query Neighborhood Hits	905	Target Neighborhood Hits	325	Shared Neighborhood Hits	159
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ADA17_MOUSE
θ value	θ > 10 (rank : 907)	NC score	0.119023 (rank : 767)
Query Neighborhood Hits	905	Target Neighborhood Hits	201	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA28_HUMAN
θ value	θ > 10 (rank : 908)	NC score	0.134320 (rank : 740)
Query Neighborhood Hits	905	Target Neighborhood Hits	244	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADAM2_HUMAN
θ value	θ > 10 (rank : 909)	NC score	0.128938 (rank : 752)
Query Neighborhood Hits	905	Target Neighborhood Hits	175	Shared Neighborhood Hits	137
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM7_MOUSE
θ value	θ > 10 (rank : 910)	NC score	0.118243 (rank : 768)
Query Neighborhood Hits	905	Target Neighborhood Hits	200	Shared Neighborhood Hits	152
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADEC1_HUMAN
θ value	θ > 10 (rank : 911)	NC score	0.050520 (rank : 989)
Query Neighborhood Hits	905	Target Neighborhood Hits	80	Shared Neighborhood Hits	40
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	θ > 10 (rank : 912)	NC score	0.052809 (rank : 971)
Query Neighborhood Hits	905	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ANKF1_HUMAN
θ value	θ > 10 (rank : 913)	NC score	0.072124 (rank : 870)
Query Neighborhood Hits	905	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKY1_HUMAN
θ value	θ > 10 (rank : 914)	NC score	0.273588 (rank : 537)
Query Neighborhood Hits	905	Target Neighborhood Hits	248	Shared Neighborhood Hits	204
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ASTN_HUMAN
θ value	θ > 10 (rank : 915)	NC score	0.148832 (rank : 701)
Query Neighborhood Hits	905	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

BAI1_HUMAN
θ value	θ > 10 (rank : 916)	NC score	0.091933 (rank : 815)
Query Neighborhood Hits	905	Target Neighborhood Hits	375	Shared Neighborhood Hits	81
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	θ > 10 (rank : 917)	NC score	0.085942 (rank : 826)
Query Neighborhood Hits	905	Target Neighborhood Hits	340	Shared Neighborhood Hits	78
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI3_HUMAN
θ value	θ > 10 (rank : 918)	NC score	0.086879 (rank : 823)
Query Neighborhood Hits	905	Target Neighborhood Hits	246	Shared Neighborhood Hits	71
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	θ > 10 (rank : 919)	NC score	0.089354 (rank : 820)
Query Neighborhood Hits	905	Target Neighborhood Hits	250	Shared Neighborhood Hits	78
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BMPER_HUMAN
θ value	θ > 10 (rank : 920)	NC score	0.189172 (rank : 646)
Query Neighborhood Hits	905	Target Neighborhood Hits	175	Shared Neighborhood Hits	128
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 921)	NC score	0.206416 (rank : 614)
Query Neighborhood Hits	905	Target Neighborhood Hits	194	Shared Neighborhood Hits	141
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CFAB_MOUSE
θ value	θ > 10 (rank : 922)	NC score	0.052826 (rank : 970)
Query Neighborhood Hits	905	Target Neighborhood Hits	262	Shared Neighborhood Hits	67
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAI_HUMAN
θ value	θ > 10 (rank : 923)	NC score	0.074780 (rank : 863)
Query Neighborhood Hits	905	Target Neighborhood Hits	289	Shared Neighborhood Hits	90
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_MOUSE
θ value	θ > 10 (rank : 924)	NC score	0.078033 (rank : 851)
Query Neighborhood Hits	905	Target Neighborhood Hits	290	Shared Neighborhood Hits	99
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CHRD_HUMAN
θ value	θ > 10 (rank : 925)	NC score	0.085352 (rank : 830)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 926)	NC score	0.080201 (rank : 844)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CMTA1_HUMAN
θ value	θ > 10 (rank : 927)	NC score	0.097419 (rank : 803)
Query Neighborhood Hits	905	Target Neighborhood Hits	217	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

COCA1_HUMAN
θ value	θ > 10 (rank : 928)	NC score	0.066803 (rank : 892)
Query Neighborhood Hits	905	Target Neighborhood Hits	458	Shared Neighborhood Hits	54
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 929)	NC score	0.070130 (rank : 877)
Query Neighborhood Hits	905	Target Neighborhood Hits	467	Shared Neighborhood Hits	56
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	θ > 10 (rank : 930)	NC score	0.060517 (rank : 924)
Query Neighborhood Hits	905	Target Neighborhood Hits	427	Shared Neighborhood Hits	48
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 931)	NC score	0.063027 (rank : 915)
Query Neighborhood Hits	905	Target Neighborhood Hits	402	Shared Neighborhood Hits	44
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COKA1_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.067150 (rank : 891)
Query Neighborhood Hits	905	Target Neighborhood Hits	403	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CRDL1_HUMAN
θ value	θ > 10 (rank : 933)	NC score	0.059088 (rank : 934)
Query Neighborhood Hits	905	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_MOUSE
θ value	θ > 10 (rank : 934)	NC score	0.060175 (rank : 927)
Query Neighborhood Hits	905	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
θ value	θ > 10 (rank : 935)	NC score	0.077984 (rank : 854)
Query Neighborhood Hits	905	Target Neighborhood Hits	99	Shared Neighborhood Hits	56
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 936)	NC score	0.080112 (rank : 845)
Query Neighborhood Hits	905	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CSMD1_HUMAN
θ value	θ > 10 (rank : 937)	NC score	0.063475 (rank : 912)
Query Neighborhood Hits	905	Target Neighborhood Hits	176	Shared Neighborhood Hits	74
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 938)	NC score	0.064385 (rank : 900)
Query Neighborhood Hits	905	Target Neighborhood Hits	193	Shared Neighborhood Hits	84
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 939)	NC score	0.056106 (rank : 949)
Query Neighborhood Hits	905	Target Neighborhood Hits	188	Shared Neighborhood Hits	70
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 940)	NC score	0.062022 (rank : 918)
Query Neighborhood Hits	905	Target Neighborhood Hits	199	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSPG4_HUMAN
θ value	θ > 10 (rank : 941)	NC score	0.064545 (rank : 897)
Query Neighborhood Hits	905	Target Neighborhood Hits	112	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 942)	NC score	0.064895 (rank : 896)
Query Neighborhood Hits	905	Target Neighborhood Hits	105	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CT127_HUMAN
θ value	θ > 10 (rank : 943)	NC score	0.090835 (rank : 816)
Query Neighborhood Hits	905	Target Neighborhood Hits	67	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CU081_HUMAN
θ value	θ > 10 (rank : 944)	NC score	0.063957 (rank : 907)
Query Neighborhood Hits	905	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

DCBD1_HUMAN
θ value	θ > 10 (rank : 945)	NC score	0.052315 (rank : 976)
Query Neighborhood Hits	905	Target Neighborhood Hits	110	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

ENTK_HUMAN
θ value	θ > 10 (rank : 946)	NC score	0.059734 (rank : 929)
Query Neighborhood Hits	905	Target Neighborhood Hits	310	Shared Neighborhood Hits	91
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ENTK_MOUSE
θ value	θ > 10 (rank : 947)	NC score	0.064248 (rank : 902)
Query Neighborhood Hits	905	Target Neighborhood Hits	338	Shared Neighborhood Hits	97
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

EPGN_HUMAN
θ value	θ > 10 (rank : 948)	NC score	0.107784 (rank : 781)
Query Neighborhood Hits	905	Target Neighborhood Hits	59	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EREG_MOUSE
θ value	θ > 10 (rank : 949)	NC score	0.098376 (rank : 798)
Query Neighborhood Hits	905	Target Neighborhood Hits	65	Shared Neighborhood Hits	53
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ESM1_MOUSE
θ value	θ > 10 (rank : 950)	NC score	0.150586 (rank : 700)
Query Neighborhood Hits	905	Target Neighborhood Hits	107	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FCN3_HUMAN
θ value	θ > 10 (rank : 951)	NC score	0.050610 (rank : 988)
Query Neighborhood Hits	905	Target Neighborhood Hits	125	Shared Neighborhood Hits	19
SwissProt Accessions	O75636, Q6IBJ5, Q8WW86	Gene names	FCN3, HAKA1
Domain Architecture
Description	Ficolin-3 precursor (Collagen/fibrinogen domain-containing protein 3) (Collagen/fibrinogen domain-containing lectin 3 p35) (Hakata antigen).

FINC_HUMAN
θ value	θ > 10 (rank : 952)	NC score	0.093810 (rank : 811)
Query Neighborhood Hits	905	Target Neighborhood Hits	302	Shared Neighborhood Hits	62
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 953)	NC score	0.094384 (rank : 809)
Query Neighborhood Hits	905	Target Neighborhood Hits	309	Shared Neighborhood Hits	69
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

GLSK_HUMAN
θ value	θ > 10 (rank : 954)	NC score	0.244310 (rank : 570)
Query Neighborhood Hits	905	Target Neighborhood Hits	204	Shared Neighborhood Hits	186
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

GLU2B_HUMAN
θ value	θ > 10 (rank : 955)	NC score	0.053288 (rank : 968)
Query Neighborhood Hits	905	Target Neighborhood Hits	377	Shared Neighborhood Hits	49
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GP110_HUMAN
θ value	θ > 10 (rank : 956)	NC score	0.061402 (rank : 921)
Query Neighborhood Hits	905	Target Neighborhood Hits	87	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP110_MOUSE
θ value	θ > 10 (rank : 957)	NC score	0.061243 (rank : 922)
Query Neighborhood Hits	905	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP111_HUMAN
θ value	θ > 10 (rank : 958)	NC score	0.055498 (rank : 955)
Query Neighborhood Hits	905	Target Neighborhood Hits	77	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

GP112_HUMAN
θ value	θ > 10 (rank : 959)	NC score	0.072689 (rank : 868)
Query Neighborhood Hits	905	Target Neighborhood Hits	441	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP113_HUMAN
θ value	θ > 10 (rank : 960)	NC score	0.079133 (rank : 848)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP114_HUMAN
θ value	θ > 10 (rank : 961)	NC score	0.068341 (rank : 883)
Query Neighborhood Hits	905	Target Neighborhood Hits	75	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP115_HUMAN
θ value	θ > 10 (rank : 962)	NC score	0.057835 (rank : 943)
Query Neighborhood Hits	905	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GP115_MOUSE
θ value	θ > 10 (rank : 963)	NC score	0.059554 (rank : 930)
Query Neighborhood Hits	905	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GP116_HUMAN
θ value	θ > 10 (rank : 964)	NC score	0.069122 (rank : 880)
Query Neighborhood Hits	905	Target Neighborhood Hits	167	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP123_HUMAN
θ value	θ > 10 (rank : 965)	NC score	0.056046 (rank : 951)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

GP124_HUMAN
θ value	θ > 10 (rank : 966)	NC score	0.064527 (rank : 899)
Query Neighborhood Hits	905	Target Neighborhood Hits	304	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP124_MOUSE
θ value	θ > 10 (rank : 967)	NC score	0.067357 (rank : 890)
Query Neighborhood Hits	905	Target Neighborhood Hits	423	Shared Neighborhood Hits	43
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_HUMAN
θ value	θ > 10 (rank : 968)	NC score	0.067646 (rank : 888)
Query Neighborhood Hits	905	Target Neighborhood Hits	327	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP125_MOUSE
θ value	θ > 10 (rank : 969)	NC score	0.063535 (rank : 911)
Query Neighborhood Hits	905	Target Neighborhood Hits	329	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP126_HUMAN
θ value	θ > 10 (rank : 970)	NC score	0.078001 (rank : 852)
Query Neighborhood Hits	905	Target Neighborhood Hits	187	Shared Neighborhood Hits	47
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP133_HUMAN
θ value	θ > 10 (rank : 971)	NC score	0.073562 (rank : 865)
Query Neighborhood Hits	905	Target Neighborhood Hits	115	Shared Neighborhood Hits	19
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP144_HUMAN
θ value	θ > 10 (rank : 972)	NC score	0.075952 (rank : 858)
Query Neighborhood Hits	905	Target Neighborhood Hits	108	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GPR56_HUMAN
θ value	θ > 10 (rank : 973)	NC score	0.063790 (rank : 909)
Query Neighborhood Hits	905	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GPR56_MOUSE
θ value	θ > 10 (rank : 974)	NC score	0.063994 (rank : 906)
Query Neighborhood Hits	905	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

GPR64_HUMAN
θ value	θ > 10 (rank : 975)	NC score	0.067768 (rank : 886)
Query Neighborhood Hits	905	Target Neighborhood Hits	207	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GPR64_MOUSE
θ value	θ > 10 (rank : 976)	NC score	0.069020 (rank : 881)
Query Neighborhood Hits	905	Target Neighborhood Hits	156	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR97_HUMAN
θ value	θ > 10 (rank : 977)	NC score	0.058439 (rank : 940)
Query Neighborhood Hits	905	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

GPR97_MOUSE
θ value	θ > 10 (rank : 978)	NC score	0.064221 (rank : 903)
Query Neighborhood Hits	905	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

GPR98_HUMAN
θ value	θ > 10 (rank : 979)	NC score	0.055649 (rank : 954)
Query Neighborhood Hits	905	Target Neighborhood Hits	202	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GPR98_MOUSE
θ value	θ > 10 (rank : 980)	NC score	0.053794 (rank : 965)
Query Neighborhood Hits	905	Target Neighborhood Hits	206	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

HPLN1_HUMAN
θ value	θ > 10 (rank : 981)	NC score	0.059382 (rank : 932)
Query Neighborhood Hits	905	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN1_MOUSE
θ value	θ > 10 (rank : 982)	NC score	0.059410 (rank : 931)
Query Neighborhood Hits	905	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN2_HUMAN
θ value	θ > 10 (rank : 983)	NC score	0.062141 (rank : 917)
Query Neighborhood Hits	905	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN2_MOUSE
θ value	θ > 10 (rank : 984)	NC score	0.063068 (rank : 914)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN3_HUMAN
θ value	θ > 10 (rank : 985)	NC score	0.060416 (rank : 925)
Query Neighborhood Hits	905	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

HPLN3_MOUSE
θ value	θ > 10 (rank : 986)	NC score	0.061770 (rank : 920)
Query Neighborhood Hits	905	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

HPLN4_HUMAN
θ value	θ > 10 (rank : 987)	NC score	0.059115 (rank : 933)
Query Neighborhood Hits	905	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

HPLN4_MOUSE
θ value	θ > 10 (rank : 988)	NC score	0.059789 (rank : 928)
Query Neighborhood Hits	905	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

IDD_HUMAN
θ value	θ > 10 (rank : 989)	NC score	0.073999 (rank : 864)
Query Neighborhood Hits	905	Target Neighborhood Hits	127	Shared Neighborhood Hits	53
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

IDD_MOUSE
θ value	θ > 10 (rank : 990)	NC score	0.069938 (rank : 878)
Query Neighborhood Hits	905	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

KR111_HUMAN
θ value	θ > 10 (rank : 991)	NC score	0.102000 (rank : 788)
Query Neighborhood Hits	905	Target Neighborhood Hits	90	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

KR121_HUMAN
θ value	θ > 10 (rank : 992)	NC score	0.051884 (rank : 981)
Query Neighborhood Hits	905	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	P59990	Gene names	KRTAP12-1, KAP12.1, KRTAP12.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-1 (Keratin-associated protein 12.1) (High sulfur keratin-associated protein 12.1).

KR131_HUMAN
θ value	θ > 10 (rank : 993)	NC score	0.070258 (rank : 876)
Query Neighborhood Hits	905	Target Neighborhood Hits	123	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

KR132_HUMAN
θ value	θ > 10 (rank : 994)	NC score	0.056919 (rank : 945)
Query Neighborhood Hits	905	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

KR133_HUMAN
θ value	θ > 10 (rank : 995)	NC score	0.059046 (rank : 936)
Query Neighborhood Hits	905	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

KR134_HUMAN
θ value	θ > 10 (rank : 996)	NC score	0.064163 (rank : 904)
Query Neighborhood Hits	905	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

KR241_HUMAN
θ value	θ > 10 (rank : 997)	NC score	0.082306 (rank : 840)
Query Neighborhood Hits	905	Target Neighborhood Hits	71	Shared Neighborhood Hits	54
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

KREM1_MOUSE
θ value	θ > 10 (rank : 998)	NC score	0.052404 (rank : 974)
Query Neighborhood Hits	905	Target Neighborhood Hits	92	Shared Neighborhood Hits	39
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 999)	NC score	0.052297 (rank : 977)
Query Neighborhood Hits	905	Target Neighborhood Hits	93	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LCE2C_HUMAN
θ value	θ > 10 (rank : 1000)	NC score	0.160632 (rank : 678)
Query Neighborhood Hits	905	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE3B_HUMAN
θ value	θ > 10 (rank : 1001)	NC score	0.126662 (rank : 756)
Query Neighborhood Hits	905	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE4A_HUMAN
θ value	θ > 10 (rank : 1002)	NC score	0.147276 (rank : 704)
Query Neighborhood Hits	905	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 1003)	NC score	0.114293 (rank : 770)
Query Neighborhood Hits	905	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LPHN1_HUMAN
θ value	θ > 10 (rank : 1004)	NC score	0.070748 (rank : 873)
Query Neighborhood Hits	905	Target Neighborhood Hits	155	Shared Neighborhood Hits	20
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
θ value	θ > 10 (rank : 1005)	NC score	0.071893 (rank : 871)
Query Neighborhood Hits	905	Target Neighborhood Hits	136	Shared Neighborhood Hits	22
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LPHN3_HUMAN
θ value	θ > 10 (rank : 1006)	NC score	0.071427 (rank : 872)
Query Neighborhood Hits	905	Target Neighborhood Hits	139	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LRP11_HUMAN
θ value	θ > 10 (rank : 1007)	NC score	0.050952 (rank : 986)
Query Neighborhood Hits	905	Target Neighborhood Hits	82	Shared Neighborhood Hits	38
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP11_MOUSE
θ value	θ > 10 (rank : 1008)	NC score	0.052761 (rank : 972)
Query Neighborhood Hits	905	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP6_HUMAN
θ value	θ > 10 (rank : 1009)	NC score	0.248375 (rank : 565)
Query Neighborhood Hits	905	Target Neighborhood Hits	235	Shared Neighborhood Hits	174
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 1010)	NC score	0.244724 (rank : 568)
Query Neighborhood Hits	905	Target Neighborhood Hits	232	Shared Neighborhood Hits	172
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MATN1_MOUSE
θ value	θ > 10 (rank : 1011)	NC score	0.194196 (rank : 631)
Query Neighborhood Hits	905	Target Neighborhood Hits	186	Shared Neighborhood Hits	137
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MCSP_HUMAN
θ value	θ > 10 (rank : 1012)	NC score	0.061901 (rank : 919)
Query Neighborhood Hits	905	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MFAP4_HUMAN
θ value	θ > 10 (rank : 1013)	NC score	0.052082 (rank : 980)
Query Neighborhood Hits	905	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_MOUSE
θ value	θ > 10 (rank : 1014)	NC score	0.052148 (rank : 979)
Query Neighborhood Hits	905	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

MFRP_HUMAN
θ value	θ > 10 (rank : 1015)	NC score	0.075800 (rank : 860)
Query Neighborhood Hits	905	Target Neighborhood Hits	165	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 1016)	NC score	0.064280 (rank : 901)
Query Neighborhood Hits	905	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MT1A_HUMAN
θ value	θ > 10 (rank : 1017)	NC score	0.086955 (rank : 822)
Query Neighborhood Hits	905	Target Neighborhood Hits	74	Shared Neighborhood Hits	52
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
θ value	θ > 10 (rank : 1018)	NC score	0.089421 (rank : 818)
Query Neighborhood Hits	905	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1E_HUMAN
θ value	θ > 10 (rank : 1019)	NC score	0.054728 (rank : 959)
Query Neighborhood Hits	905	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT1H_HUMAN
θ value	θ > 10 (rank : 1020)	NC score	0.070372 (rank : 875)
Query Neighborhood Hits	905	Target Neighborhood Hits	78	Shared Neighborhood Hits	52
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT1L_HUMAN
θ value	θ > 10 (rank : 1021)	NC score	0.059074 (rank : 935)
Query Neighborhood Hits	905	Target Neighborhood Hits	73	Shared Neighborhood Hits	48
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT1X_HUMAN
θ value	θ > 10 (rank : 1022)	NC score	0.081736 (rank : 841)
Query Neighborhood Hits	905	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT1_MOUSE
θ value	θ > 10 (rank : 1023)	NC score	0.073199 (rank : 867)
Query Neighborhood Hits	905	Target Neighborhood Hits	72	Shared Neighborhood Hits	45
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_MOUSE
θ value	θ > 10 (rank : 1024)	NC score	0.078771 (rank : 850)
Query Neighborhood Hits	905	Target Neighborhood Hits	81	Shared Neighborhood Hits	49
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT3_HUMAN
θ value	θ > 10 (rank : 1025)	NC score	0.160716 (rank : 677)
Query Neighborhood Hits	905	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 1026)	NC score	0.173611 (rank : 661)
Query Neighborhood Hits	905	Target Neighborhood Hits	68	Shared Neighborhood Hits	54
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

NETO1_HUMAN
θ value	θ > 10 (rank : 1027)	NC score	0.056419 (rank : 948)
Query Neighborhood Hits	905	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 1028)	NC score	0.056049 (rank : 950)
Query Neighborhood Hits	905	Target Neighborhood Hits	109	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 1029)	NC score	0.054171 (rank : 963)
Query Neighborhood Hits	905	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 1030)	NC score	0.054137 (rank : 964)
Query Neighborhood Hits	905	Target Neighborhood Hits	113	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRP1_HUMAN
θ value	θ > 10 (rank : 1031)	NC score	0.055958 (rank : 952)
Query Neighborhood Hits	905	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 1032)	NC score	0.055435 (rank : 956)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 1033)	NC score	0.060211 (rank : 926)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 1034)	NC score	0.057738 (rank : 944)
Query Neighborhood Hits	905	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRX1B_HUMAN
θ value	θ > 10 (rank : 1035)	NC score	0.053369 (rank : 967)
Query Neighborhood Hits	905	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

ODFP_MOUSE
θ value	θ > 10 (rank : 1036)	NC score	0.068366 (rank : 882)
Query Neighborhood Hits	905	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PGCA_MOUSE
θ value	θ > 10 (rank : 1037)	NC score	0.055256 (rank : 957)
Query Neighborhood Hits	905	Target Neighborhood Hits	643	Shared Neighborhood Hits	57
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PHXR5_MOUSE
θ value	θ > 10 (rank : 1038)	NC score	0.171204 (rank : 665)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	74
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PROP_HUMAN
θ value	θ > 10 (rank : 1039)	NC score	0.058587 (rank : 938)
Query Neighborhood Hits	905	Target Neighborhood Hits	126	Shared Neighborhood Hits	46
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

RSPO1_HUMAN
θ value	θ > 10 (rank : 1040)	NC score	0.050648 (rank : 987)
Query Neighborhood Hits	905	Target Neighborhood Hits	101	Shared Neighborhood Hits	52
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO2_HUMAN
θ value	θ > 10 (rank : 1041)	NC score	0.064967 (rank : 895)
Query Neighborhood Hits	905	Target Neighborhood Hits	90	Shared Neighborhood Hits	52
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
θ value	θ > 10 (rank : 1042)	NC score	0.066659 (rank : 893)
Query Neighborhood Hits	905	Target Neighborhood Hits	88	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO4_MOUSE
θ value	θ > 10 (rank : 1043)	NC score	0.077733 (rank : 855)
Query Neighborhood Hits	905	Target Neighborhood Hits	110	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SHBG_HUMAN
θ value	θ > 10 (rank : 1044)	NC score	0.113594 (rank : 774)
Query Neighborhood Hits	905	Target Neighborhood Hits	45	Shared Neighborhood Hits	35
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SHBG_MOUSE
θ value	θ > 10 (rank : 1045)	NC score	0.109772 (rank : 778)
Query Neighborhood Hits	905	Target Neighborhood Hits	50	Shared Neighborhood Hits	40
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SNCAP_HUMAN
θ value	θ > 10 (rank : 1046)	NC score	0.350554 (rank : 452)
Query Neighborhood Hits	905	Target Neighborhood Hits	313	Shared Neighborhood Hits	236
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

SPIT1_HUMAN
θ value	θ > 10 (rank : 1047)	NC score	0.054964 (rank : 958)
Query Neighborhood Hits	905	Target Neighborhood Hits	100	Shared Neighborhood Hits	48
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPIT1_MOUSE
θ value	θ > 10 (rank : 1048)	NC score	0.052539 (rank : 973)
Query Neighborhood Hits	905	Target Neighborhood Hits	96	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPR2B_MOUSE
θ value	θ > 10 (rank : 1049)	NC score	0.083428 (rank : 837)
Query Neighborhood Hits	905	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2D_MOUSE
θ value	θ > 10 (rank : 1050)	NC score	0.102880 (rank : 786)
Query Neighborhood Hits	905	Target Neighborhood Hits	61	Shared Neighborhood Hits	25
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_HUMAN
θ value	θ > 10 (rank : 1051)	NC score	0.050100 (rank : 991)
Query Neighborhood Hits	905	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2F_HUMAN
θ value	θ > 10 (rank : 1052)	NC score	0.080532 (rank : 843)
Query Neighborhood Hits	905	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2F_MOUSE
θ value	θ > 10 (rank : 1053)	NC score	0.051381 (rank : 984)
Query Neighborhood Hits	905	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SPR2G_MOUSE
θ value	θ > 10 (rank : 1054)	NC score	0.094229 (rank : 810)
Query Neighborhood Hits	905	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 1055)	NC score	0.084457 (rank : 832)
Query Neighborhood Hits	905	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

TGFA_MOUSE
θ value	θ > 10 (rank : 1056)	NC score	0.075524 (rank : 861)
Query Neighborhood Hits	905	Target Neighborhood Hits	62	Shared Neighborhood Hits	53
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TMG1_HUMAN
θ value	θ > 10 (rank : 1057)	NC score	0.070616 (rank : 874)
Query Neighborhood Hits	905	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

TMG2_HUMAN
θ value	θ > 10 (rank : 1058)	NC score	0.054617 (rank : 960)
Query Neighborhood Hits	905	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O14669	Gene names	PRRG2, PRGP2, TMG2
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2).

TMG2_MOUSE
θ value	θ > 10 (rank : 1059)	NC score	0.052935 (rank : 969)
Query Neighborhood Hits	905	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R182, Q9EQI2	Gene names	Prrg2, N4wbp1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2) (NEDD4 WW domain-binding protein 1).

TMG3_HUMAN
θ value	θ > 10 (rank : 1060)	NC score	0.063599 (rank : 910)
Query Neighborhood Hits	905	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG3_MOUSE
θ value	θ > 10 (rank : 1061)	NC score	0.063231 (rank : 913)
Query Neighborhood Hits	905	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG4_HUMAN
θ value	θ > 10 (rank : 1062)	NC score	0.053786 (rank : 966)
Query Neighborhood Hits	905	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMPS7_HUMAN
θ value	θ > 10 (rank : 1063)	NC score	0.076149 (rank : 857)
Query Neighborhood Hits	905	Target Neighborhood Hits	275	Shared Neighborhood Hits	98
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 1064)	NC score	0.075830 (rank : 859)
Query Neighborhood Hits	905	Target Neighborhood Hits	275	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TNR11_HUMAN
θ value	θ > 10 (rank : 1065)	NC score	0.085719 (rank : 828)
Query Neighborhood Hits	905	Target Neighborhood Hits	135	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
θ value	θ > 10 (rank : 1066)	NC score	0.066266 (rank : 894)
Query Neighborhood Hits	905	Target Neighborhood Hits	121	Shared Neighborhood Hits	62
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR16_HUMAN
θ value	θ > 10 (rank : 1067)	NC score	0.139931 (rank : 724)
Query Neighborhood Hits	905	Target Neighborhood Hits	183	Shared Neighborhood Hits	111
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	θ > 10 (rank : 1068)	NC score	0.128997 (rank : 750)
Query Neighborhood Hits	905	Target Neighborhood Hits	178	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR18_HUMAN
θ value	θ > 10 (rank : 1069)	NC score	0.051150 (rank : 985)
Query Neighborhood Hits	905	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR19_HUMAN
θ value	θ > 10 (rank : 1070)	NC score	0.051539 (rank : 983)
Query Neighborhood Hits	905	Target Neighborhood Hits	89	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 1071)	NC score	0.050511 (rank : 990)
Query Neighborhood Hits	905	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR1A_HUMAN
θ value	θ > 10 (rank : 1072)	NC score	0.052198 (rank : 978)
Query Neighborhood Hits	905	Target Neighborhood Hits	121	Shared Neighborhood Hits	50
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR1A_MOUSE
θ value	θ > 10 (rank : 1073)	NC score	0.050063 (rank : 992)
Query Neighborhood Hits	905	Target Neighborhood Hits	131	Shared Neighborhood Hits	56
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR22_MOUSE
θ value	θ > 10 (rank : 1074)	NC score	0.067741 (rank : 887)
Query Neighborhood Hits	905	Target Neighborhood Hits	97	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
θ value	θ > 10 (rank : 1075)	NC score	0.078803 (rank : 849)
Query Neighborhood Hits	905	Target Neighborhood Hits	114	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR25_HUMAN
θ value	θ > 10 (rank : 1076)	NC score	0.152064 (rank : 697)
Query Neighborhood Hits	905	Target Neighborhood Hits	172	Shared Neighborhood Hits	85
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR26_MOUSE
θ value	θ > 10 (rank : 1077)	NC score	0.069424 (rank : 879)
Query Neighborhood Hits	905	Target Neighborhood Hits	106	Shared Neighborhood Hits	66
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR3_HUMAN
θ value	θ > 10 (rank : 1078)	NC score	0.051747 (rank : 982)
Query Neighborhood Hits	905	Target Neighborhood Hits	145	Shared Neighborhood Hits	58
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR3_MOUSE
θ value	θ > 10 (rank : 1079)	NC score	0.060737 (rank : 923)
Query Neighborhood Hits	905	Target Neighborhood Hits	113	Shared Neighborhood Hits	61
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR4_MOUSE
θ value	θ > 10 (rank : 1080)	NC score	0.104220 (rank : 785)
Query Neighborhood Hits	905	Target Neighborhood Hits	137	Shared Neighborhood Hits	76
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR6B_HUMAN
θ value	θ > 10 (rank : 1081)	NC score	0.058019 (rank : 942)
Query Neighborhood Hits	905	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR6_HUMAN
θ value	θ > 10 (rank : 1082)	NC score	0.052331 (rank : 975)
Query Neighborhood Hits	905	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
θ value	θ > 10 (rank : 1083)	NC score	0.058683 (rank : 937)
Query Neighborhood Hits	905	Target Neighborhood Hits	99	Shared Neighborhood Hits	54
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
θ value	θ > 10 (rank : 1084)	NC score	0.098601 (rank : 797)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR7_MOUSE
θ value	θ > 10 (rank : 1085)	NC score	0.064043 (rank : 905)
Query Neighborhood Hits	905	Target Neighborhood Hits	112	Shared Neighborhood Hits	56
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR8_HUMAN
θ value	θ > 10 (rank : 1086)	NC score	0.083737 (rank : 836)
Query Neighborhood Hits	905	Target Neighborhood Hits	198	Shared Neighborhood Hits	87
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR8_MOUSE
θ value	θ > 10 (rank : 1087)	NC score	0.101077 (rank : 790)
Query Neighborhood Hits	905	Target Neighborhood Hits	208	Shared Neighborhood Hits	89
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR9_MOUSE
θ value	θ > 10 (rank : 1088)	NC score	0.084139 (rank : 834)
Query Neighborhood Hits	905	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TSG6_HUMAN
θ value	θ > 10 (rank : 1089)	NC score	0.079552 (rank : 847)
Query Neighborhood Hits	905	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 1090)	NC score	0.079659 (rank : 846)
Query Neighborhood Hits	905	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

WFDC3_HUMAN
θ value	θ > 10 (rank : 1091)	NC score	0.161139 (rank : 675)
Query Neighborhood Hits	905	Target Neighborhood Hits	138	Shared Neighborhood Hits	102
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WISP1_HUMAN
θ value	θ > 10 (rank : 1092)	NC score	0.062653 (rank : 916)
Query Neighborhood Hits	905	Target Neighborhood Hits	121	Shared Neighborhood Hits	58
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP2_HUMAN
θ value	θ > 10 (rank : 1093)	NC score	0.074804 (rank : 862)
Query Neighborhood Hits	905	Target Neighborhood Hits	126	Shared Neighborhood Hits	55
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

ZNFX1_HUMAN
θ value	θ > 10 (rank : 1094)	NC score	0.107475 (rank : 782)
Query Neighborhood Hits	905	Target Neighborhood Hits	308	Shared Neighborhood Hits	135
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
θ value	θ > 10 (rank : 1095)	NC score	0.101033 (rank : 791)
Query Neighborhood Hits	905	Target Neighborhood Hits	407	Shared Neighborhood Hits	139
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

Hits sorted by NC score

NOTC4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 7)
Query Neighborhood Hits	905	Target Neighborhood Hits	905	Shared Neighborhood Hits	905
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
NC score	0.993703 (rank : 2)	θ value	0 (rank : 8)
Query Neighborhood Hits	905	Target Neighborhood Hits	872	Shared Neighborhood Hits	789
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC3_MOUSE
NC score	0.982456 (rank : 3)	θ value	0 (rank : 6)
Query Neighborhood Hits	905	Target Neighborhood Hits	975	Shared Neighborhood Hits	780
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.980901 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	905	Target Neighborhood Hits	1062	Shared Neighborhood Hits	774
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_HUMAN
NC score	0.980374 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	905	Target Neighborhood Hits	906	Shared Neighborhood Hits	752
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
NC score	0.976288 (rank : 6)	θ value	0 (rank : 4)
Query Neighborhood Hits	905	Target Neighborhood Hits	1069	Shared Neighborhood Hits	767
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
NC score	0.975976 (rank : 7)	θ value	0 (rank : 3)
Query Neighborhood Hits	905	Target Neighborhood Hits	1113	Shared Neighborhood Hits	778
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_MOUSE
NC score	0.971714 (rank : 8)	θ value	0 (rank : 2)
Query Neighborhood Hits	905	Target Neighborhood Hits	916	Shared Neighborhood Hits	747
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

JAG1_HUMAN
NC score	0.858548 (rank : 9)	θ value	1.28961e-139 (rank : 9)
Query Neighborhood Hits	905	Target Neighborhood Hits	514	Shared Neighborhood Hits	449
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG2_HUMAN
NC score	0.857983 (rank : 10)	θ value	6.41512e-131 (rank : 11)
Query Neighborhood Hits	905	Target Neighborhood Hits	491	Shared Neighborhood Hits	440
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG1_MOUSE
NC score	0.857788 (rank : 11)	θ value	1.20704e-137 (rank : 10)
Query Neighborhood Hits	905	Target Neighborhood Hits	518	Shared Neighborhood Hits	445
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_MOUSE
NC score	0.855951 (rank : 12)	θ value	4.15819e-130 (rank : 12)
Query Neighborhood Hits	905	Target Neighborhood Hits	504	Shared Neighborhood Hits	437
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

CRUM2_HUMAN
NC score	0.844660 (rank : 13)	θ value	6.71607e-88 (rank : 17)
Query Neighborhood Hits	905	Target Neighborhood Hits	453	Shared Neighborhood Hits	416
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

DNER_HUMAN
NC score	0.841115 (rank : 14)	θ value	1.2325e-65 (rank : 27)
Query Neighborhood Hits	905	Target Neighborhood Hits	460	Shared Neighborhood Hits	396
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

CRUM1_MOUSE
NC score	0.840110 (rank : 15)	θ value	1.49272e-95 (rank : 14)
Query Neighborhood Hits	905	Target Neighborhood Hits	444	Shared Neighborhood Hits	405
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

DLL1_MOUSE
NC score	0.839333 (rank : 16)	θ value	2.93355e-67 (rank : 23)
Query Neighborhood Hits	905	Target Neighborhood Hits	456	Shared Neighborhood Hits	421
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

CRUM1_HUMAN
NC score	0.838993 (rank : 17)	θ value	1.59483e-97 (rank : 13)
Query Neighborhood Hits	905	Target Neighborhood Hits	457	Shared Neighborhood Hits	416
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DNER_MOUSE
NC score	0.838774 (rank : 18)	θ value	2.74572e-65 (rank : 28)
Query Neighborhood Hits	905	Target Neighborhood Hits	413	Shared Neighborhood Hits	384
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DLL1_HUMAN
NC score	0.836397 (rank : 19)	θ value	3.24342e-66 (rank : 25)
Query Neighborhood Hits	905	Target Neighborhood Hits	455	Shared Neighborhood Hits	412
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL4_MOUSE
NC score	0.832722 (rank : 20)	θ value	3.71096e-62 (rank : 30)
Query Neighborhood Hits	905	Target Neighborhood Hits	440	Shared Neighborhood Hits	402
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_HUMAN
NC score	0.832333 (rank : 21)	θ value	6.32992e-62 (rank : 31)
Query Neighborhood Hits	905	Target Neighborhood Hits	435	Shared Neighborhood Hits	399
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLK_HUMAN
NC score	0.822034 (rank : 22)	θ value	1.73584e-35 (rank : 56)
Query Neighborhood Hits	905	Target Neighborhood Hits	401	Shared Neighborhood Hits	381
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

EGFL9_HUMAN
NC score	0.821058 (rank : 23)	θ value	2.34062e-40 (rank : 51)
Query Neighborhood Hits	905	Target Neighborhood Hits	365	Shared Neighborhood Hits	351
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

DLL3_HUMAN
NC score	0.820555 (rank : 24)	θ value	2.18568e-46 (rank : 46)
Query Neighborhood Hits	905	Target Neighborhood Hits	419	Shared Neighborhood Hits	382
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

EGFL9_MOUSE
NC score	0.819673 (rank : 25)	θ value	3.61106e-41 (rank : 50)
Query Neighborhood Hits	905	Target Neighborhood Hits	379	Shared Neighborhood Hits	358
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

DLL3_MOUSE
NC score	0.818795 (rank : 26)	θ value	2.04573e-44 (rank : 49)
Query Neighborhood Hits	905	Target Neighborhood Hits	399	Shared Neighborhood Hits	371
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLK_MOUSE
NC score	0.818735 (rank : 27)	θ value	1.46948e-34 (rank : 57)
Query Neighborhood Hits	905	Target Neighborhood Hits	374	Shared Neighborhood Hits	361
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

MEGF6_HUMAN
NC score	0.818515 (rank : 28)	θ value	4.65103e-89 (rank : 16)
Query Neighborhood Hits	905	Target Neighborhood Hits	671	Shared Neighborhood Hits	491
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

LTBP4_MOUSE
NC score	0.803113 (rank : 29)	θ value	3.70236e-70 (rank : 22)
Query Neighborhood Hits	905	Target Neighborhood Hits	607	Shared Neighborhood Hits	403
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FBN3_HUMAN
NC score	0.798792 (rank : 30)	θ value	9.6755e-95 (rank : 15)
Query Neighborhood Hits	905	Target Neighborhood Hits	543	Shared Neighborhood Hits	427
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN2_HUMAN
NC score	0.796860 (rank : 31)	θ value	6.95003e-85 (rank : 19)
Query Neighborhood Hits	905	Target Neighborhood Hits	560	Shared Neighborhood Hits	448
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.796604 (rank : 32)	θ value	1.44917e-82 (rank : 21)
Query Neighborhood Hits	905	Target Neighborhood Hits	563	Shared Neighborhood Hits	452
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
NC score	0.796525 (rank : 33)	θ value	9.07703e-85 (rank : 20)
Query Neighborhood Hits	905	Target Neighborhood Hits	549	Shared Neighborhood Hits	448
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_HUMAN
NC score	0.795596 (rank : 34)	θ value	1.07224e-85 (rank : 18)
Query Neighborhood Hits	905	Target Neighborhood Hits	557	Shared Neighborhood Hits	445
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP2_HUMAN
NC score	0.786723 (rank : 35)	θ value	9.43692e-66 (rank : 26)
Query Neighborhood Hits	905	Target Neighborhood Hits	552	Shared Neighborhood Hits	413
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
NC score	0.786350 (rank : 36)	θ value	2.93355e-67 (rank : 24)
Query Neighborhood Hits	905	Target Neighborhood Hits	617	Shared Neighborhood Hits	412
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
NC score	0.778330 (rank : 37)	θ value	3.36421e-55 (rank : 32)
Query Neighborhood Hits	905	Target Neighborhood Hits	502	Shared Neighborhood Hits	388
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
NC score	0.773162 (rank : 38)	θ value	2.85459e-46 (rank : 47)
Query Neighborhood Hits	905	Target Neighborhood Hits	475	Shared Neighborhood Hits	385
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NELL1_HUMAN
NC score	0.767730 (rank : 39)	θ value	8.3442e-30 (rank : 61)
Query Neighborhood Hits	905	Target Neighborhood Hits	451	Shared Neighborhood Hits	391
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

LTB1L_HUMAN
NC score	0.764373 (rank : 40)	θ value	4.54686e-52 (rank : 36)
Query Neighborhood Hits	905	Target Neighborhood Hits	553	Shared Neighborhood Hits	403
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
NC score	0.763754 (rank : 41)	θ value	1.66964e-54 (rank : 33)
Query Neighborhood Hits	905	Target Neighborhood Hits	514	Shared Neighborhood Hits	403
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.763496 (rank : 42)	θ value	4.54686e-52 (rank : 37)
Query Neighborhood Hits	905	Target Neighborhood Hits	502	Shared Neighborhood Hits	392
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NELL2_HUMAN
NC score	0.763081 (rank : 43)	θ value	8.08199e-25 (rank : 75)
Query Neighborhood Hits	905	Target Neighborhood Hits	449	Shared Neighborhood Hits	383
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
NC score	0.762988 (rank : 44)	θ value	8.08199e-25 (rank : 76)
Query Neighborhood Hits	905	Target Neighborhood Hits	436	Shared Neighborhood Hits	384
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

LTB1S_MOUSE
NC score	0.762971 (rank : 45)	θ value	1.66964e-54 (rank : 34)
Query Neighborhood Hits	905	Target Neighborhood Hits	479	Shared Neighborhood Hits	381
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

WIF1_HUMAN
NC score	0.753108 (rank : 46)	θ value	1.63225e-17 (rank : 136)
Query Neighborhood Hits	905	Target Neighborhood Hits	392	Shared Neighborhood Hits	359
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
NC score	0.750698 (rank : 47)	θ value	1.63225e-17 (rank : 137)
Query Neighborhood Hits	905	Target Neighborhood Hits	393	Shared Neighborhood Hits	362
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

SREC_HUMAN
NC score	0.745775 (rank : 48)	θ value	3.17079e-29 (rank : 62)
Query Neighborhood Hits	905	Target Neighborhood Hits	645	Shared Neighborhood Hits	417
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

FBLN2_HUMAN
NC score	0.739806 (rank : 49)	θ value	4.13158e-37 (rank : 53)
Query Neighborhood Hits	905	Target Neighborhood Hits	392	Shared Neighborhood Hits	300
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

SREC2_MOUSE
NC score	0.735700 (rank : 50)	θ value	8.08199e-25 (rank : 77)
Query Neighborhood Hits	905	Target Neighborhood Hits	605	Shared Neighborhood Hits	402
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

FBLN2_MOUSE
NC score	0.734229 (rank : 51)	θ value	1.01765e-35 (rank : 55)
Query Neighborhood Hits	905	Target Neighborhood Hits	505	Shared Neighborhood Hits	320
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

SREC2_HUMAN
NC score	0.728187 (rank : 52)	θ value	4.73814e-25 (rank : 73)
Query Neighborhood Hits	905	Target Neighborhood Hits	645	Shared Neighborhood Hits	396
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

FBLN1_HUMAN
NC score	0.726932 (rank : 53)	θ value	7.04741e-37 (rank : 54)
Query Neighborhood Hits	905	Target Neighborhood Hits	324	Shared Neighborhood Hits	297
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
NC score	0.726587 (rank : 54)	θ value	6.37413e-38 (rank : 52)
Query Neighborhood Hits	905	Target Neighborhood Hits	329	Shared Neighborhood Hits	293
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

C1QR1_HUMAN
NC score	0.723881 (rank : 55)	θ value	2.87452e-22 (rank : 86)
Query Neighborhood Hits	905	Target Neighborhood Hits	493	Shared Neighborhood Hits	326
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
NC score	0.721367 (rank : 56)	θ value	2.87452e-22 (rank : 87)
Query Neighborhood Hits	905	Target Neighborhood Hits	342	Shared Neighborhood Hits	298
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

SCUB3_HUMAN
NC score	0.714946 (rank : 57)	θ value	5.97985e-28 (rank : 66)
Query Neighborhood Hits	905	Target Neighborhood Hits	428	Shared Neighborhood Hits	312
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
NC score	0.714777 (rank : 58)	θ value	9.2256e-29 (rank : 63)
Query Neighborhood Hits	905	Target Neighborhood Hits	442	Shared Neighborhood Hits	321
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

STAB2_HUMAN
NC score	0.711896 (rank : 59)	θ value	1.86321e-21 (rank : 95)
Query Neighborhood Hits	905	Target Neighborhood Hits	534	Shared Neighborhood Hits	417
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB1_HUMAN
NC score	0.710205 (rank : 60)	θ value	1.2077e-20 (rank : 106)
Query Neighborhood Hits	905	Target Neighborhood Hits	546	Shared Neighborhood Hits	414
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
NC score	0.708827 (rank : 61)	θ value	4.15078e-21 (rank : 99)
Query Neighborhood Hits	905	Target Neighborhood Hits	566	Shared Neighborhood Hits	437
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

GAS6_MOUSE
NC score	0.708122 (rank : 62)	θ value	3.75424e-22 (rank : 90)
Query Neighborhood Hits	905	Target Neighborhood Hits	343	Shared Neighborhood Hits	316
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

STAB2_MOUSE
NC score	0.707554 (rank : 63)	θ value	7.56453e-23 (rank : 84)
Query Neighborhood Hits	905	Target Neighborhood Hits	528	Shared Neighborhood Hits	409
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

GAS6_HUMAN
NC score	0.705270 (rank : 64)	θ value	4.58923e-20 (rank : 112)
Query Neighborhood Hits	905	Target Neighborhood Hits	348	Shared Neighborhood Hits	315
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBLN4_HUMAN
NC score	0.703278 (rank : 65)	θ value	3.75424e-22 (rank : 89)
Query Neighborhood Hits	905	Target Neighborhood Hits	278	Shared Neighborhood Hits	252
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN5_HUMAN
NC score	0.700552 (rank : 66)	θ value	3.07116e-24 (rank : 78)
Query Neighborhood Hits	905	Target Neighborhood Hits	329	Shared Neighborhood Hits	297
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

TRBM_HUMAN
NC score	0.700156 (rank : 67)	θ value	1.47631e-18 (rank : 121)
Query Neighborhood Hits	905	Target Neighborhood Hits	339	Shared Neighborhood Hits	286
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

PROS_HUMAN
NC score	0.700007 (rank : 68)	θ value	2.69047e-20 (rank : 111)
Query Neighborhood Hits	905	Target Neighborhood Hits	340	Shared Neighborhood Hits	319
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

FBLN4_MOUSE
NC score	0.696774 (rank : 69)	θ value	3.17815e-21 (rank : 97)
Query Neighborhood Hits	905	Target Neighborhood Hits	270	Shared Neighborhood Hits	245
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_MOUSE
NC score	0.696237 (rank : 70)	θ value	9.24701e-21 (rank : 101)
Query Neighborhood Hits	905	Target Neighborhood Hits	317	Shared Neighborhood Hits	284
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

PROS_MOUSE
NC score	0.696171 (rank : 71)	θ value	1.33526e-19 (rank : 115)
Query Neighborhood Hits	905	Target Neighborhood Hits	330	Shared Neighborhood Hits	305
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

FBLN3_HUMAN
NC score	0.691586 (rank : 72)	θ value	8.08199e-25 (rank : 74)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	267
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

TRBM_MOUSE
NC score	0.686527 (rank : 73)	θ value	3.07829e-16 (rank : 156)
Query Neighborhood Hits	905	Target Neighborhood Hits	361	Shared Neighborhood Hits	292
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

EGFL7_HUMAN
NC score	0.686093 (rank : 74)	θ value	6.00763e-12 (rank : 223)
Query Neighborhood Hits	905	Target Neighborhood Hits	325	Shared Neighborhood Hits	296
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

CUBN_MOUSE
NC score	0.685246 (rank : 75)	θ value	1.61718e-49 (rank : 41)
Query Neighborhood Hits	905	Target Neighborhood Hits	477	Shared Neighborhood Hits	374
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

FBLN3_MOUSE
NC score	0.684678 (rank : 76)	θ value	7.30988e-26 (rank : 71)
Query Neighborhood Hits	905	Target Neighborhood Hits	279	Shared Neighborhood Hits	255
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

CUBN_HUMAN
NC score	0.682551 (rank : 77)	θ value	1.11993e-50 (rank : 38)
Query Neighborhood Hits	905	Target Neighborhood Hits	482	Shared Neighborhood Hits	385
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CREL1_HUMAN
NC score	0.679222 (rank : 78)	θ value	1.38499e-08 (rank : 330)
Query Neighborhood Hits	905	Target Neighborhood Hits	441	Shared Neighborhood Hits	291
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EGFL7_MOUSE
NC score	0.679095 (rank : 79)	θ value	4.59992e-12 (rank : 218)
Query Neighborhood Hits	905	Target Neighborhood Hits	287	Shared Neighborhood Hits	270
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

CREL1_MOUSE
NC score	0.667350 (rank : 80)	θ value	2.61198e-07 (rank : 375)
Query Neighborhood Hits	905	Target Neighborhood Hits	524	Shared Neighborhood Hits	301
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EGFL8_MOUSE
NC score	0.660236 (rank : 81)	θ value	1.25267e-09 (rank : 309)
Query Neighborhood Hits	905	Target Neighborhood Hits	266	Shared Neighborhood Hits	256
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

UROM_HUMAN
NC score	0.658505 (rank : 82)	θ value	4.74913e-17 (rank : 145)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	259
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

EGFL8_HUMAN
NC score	0.656051 (rank : 83)	θ value	5.62301e-10 (rank : 280)
Query Neighborhood Hits	905	Target Neighborhood Hits	270	Shared Neighborhood Hits	252
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

AGRIN_HUMAN
NC score	0.655592 (rank : 84)	θ value	2.43343e-21 (rank : 96)
Query Neighborhood Hits	905	Target Neighborhood Hits	582	Shared Neighborhood Hits	400
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

NID2_HUMAN
NC score	0.651661 (rank : 85)	θ value	4.74913e-17 (rank : 144)
Query Neighborhood Hits	905	Target Neighborhood Hits	456	Shared Neighborhood Hits	291
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

EGF_MOUSE
NC score	0.650078 (rank : 86)	θ value	6.20254e-17 (rank : 148)
Query Neighborhood Hits	905	Target Neighborhood Hits	358	Shared Neighborhood Hits	321
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

MEGF8_HUMAN
NC score	0.649441 (rank : 87)	θ value	1.58096e-12 (rank : 209)
Query Neighborhood Hits	905	Target Neighborhood Hits	528	Shared Neighborhood Hits	359
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NID2_MOUSE
NC score	0.649435 (rank : 88)	θ value	1.13037e-18 (rank : 120)
Query Neighborhood Hits	905	Target Neighborhood Hits	338	Shared Neighborhood Hits	284
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

UROM_MOUSE
NC score	0.646956 (rank : 89)	θ value	1.52774e-15 (rank : 164)
Query Neighborhood Hits	905	Target Neighborhood Hits	276	Shared Neighborhood Hits	250
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

SUSD1_HUMAN
NC score	0.646389 (rank : 90)	θ value	5.43371e-13 (rank : 200)
Query Neighborhood Hits	905	Target Neighborhood Hits	285	Shared Neighborhood Hits	233
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

MEGF8_MOUSE
NC score	0.644276 (rank : 91)	θ value	1.09485e-13 (rank : 186)
Query Neighborhood Hits	905	Target Neighborhood Hits	520	Shared Neighborhood Hits	353
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NID1_MOUSE
NC score	0.643870 (rank : 92)	θ value	1.13037e-18 (rank : 119)
Query Neighborhood Hits	905	Target Neighborhood Hits	335	Shared Neighborhood Hits	272
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_HUMAN
NC score	0.643178 (rank : 93)	θ value	2.13179e-17 (rank : 139)
Query Neighborhood Hits	905	Target Neighborhood Hits	329	Shared Neighborhood Hits	282
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

MATN2_HUMAN
NC score	0.641520 (rank : 94)	θ value	4.43474e-23 (rank : 81)
Query Neighborhood Hits	905	Target Neighborhood Hits	365	Shared Neighborhood Hits	275
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

TSP4_MOUSE
NC score	0.632660 (rank : 95)	θ value	8.10077e-17 (rank : 150)
Query Neighborhood Hits	905	Target Neighborhood Hits	276	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

MATN2_MOUSE
NC score	0.629986 (rank : 96)	θ value	4.15078e-21 (rank : 98)
Query Neighborhood Hits	905	Target Neighborhood Hits	356	Shared Neighborhood Hits	272
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

TSP4_HUMAN
NC score	0.629277 (rank : 97)	θ value	4.02038e-16 (rank : 157)
Query Neighborhood Hits	905	Target Neighborhood Hits	277	Shared Neighborhood Hits	255
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

LRP1_HUMAN
NC score	0.628727 (rank : 98)	θ value	1.98606e-31 (rank : 60)
Query Neighborhood Hits	905	Target Neighborhood Hits	617	Shared Neighborhood Hits	452
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

TENX_HUMAN
NC score	0.624924 (rank : 99)	θ value	4.38363e-63 (rank : 29)
Query Neighborhood Hits	905	Target Neighborhood Hits	789	Shared Neighborhood Hits	414
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LRP1B_HUMAN
NC score	0.624195 (rank : 100)	θ value	4.57862e-28 (rank : 65)
Query Neighborhood Hits	905	Target Neighborhood Hits	602	Shared Neighborhood Hits	460
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TENA_HUMAN
NC score	0.623551 (rank : 101)	θ value	1.61718e-49 (rank : 43)
Query Neighborhood Hits	905	Target Neighborhood Hits	631	Shared Neighborhood Hits	393
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

LRP1B_MOUSE
NC score	0.620834 (rank : 102)	θ value	1.12775e-26 (rank : 68)
Query Neighborhood Hits	905	Target Neighborhood Hits	606	Shared Neighborhood Hits	455
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EDIL3_MOUSE
NC score	0.619416 (rank : 103)	θ value	9.24701e-21 (rank : 100)
Query Neighborhood Hits	905	Target Neighborhood Hits	317	Shared Neighborhood Hits	288
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EMR1_HUMAN
NC score	0.618953 (rank : 104)	θ value	3.28125e-26 (rank : 69)
Query Neighborhood Hits	905	Target Neighborhood Hits	382	Shared Neighborhood Hits	288
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

TENA_MOUSE
NC score	0.618639 (rank : 105)	θ value	1.15895e-47 (rank : 44)
Query Neighborhood Hits	905	Target Neighborhood Hits	596	Shared Neighborhood Hits	386
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

EGF_HUMAN
NC score	0.617274 (rank : 106)	θ value	1.42992e-13 (rank : 190)
Query Neighborhood Hits	905	Target Neighborhood Hits	343	Shared Neighborhood Hits	302
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

COMP_MOUSE
NC score	0.613419 (rank : 107)	θ value	1.52774e-15 (rank : 163)
Query Neighborhood Hits	905	Target Neighborhood Hits	290	Shared Neighborhood Hits	256
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

KRA53_HUMAN
NC score	0.611236 (rank : 108)	θ value	1.09739e-05 (rank : 434)
Query Neighborhood Hits	905	Target Neighborhood Hits	331	Shared Neighborhood Hits	261
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

EDIL3_HUMAN
NC score	0.610067 (rank : 109)	θ value	1.74391e-19 (rank : 116)
Query Neighborhood Hits	905	Target Neighborhood Hits	292	Shared Neighborhood Hits	266
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

KRA51_HUMAN
NC score	0.607648 (rank : 110)	θ value	0.000158464 (rank : 471)
Query Neighborhood Hits	905	Target Neighborhood Hits	288	Shared Neighborhood Hits	223
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

SLIT1_MOUSE
NC score	0.601740 (rank : 111)	θ value	5.55816e-50 (rank : 40)
Query Neighborhood Hits	905	Target Neighborhood Hits	715	Shared Neighborhood Hits	393
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT1_HUMAN
NC score	0.601215 (rank : 112)	θ value	1.19655e-52 (rank : 35)
Query Neighborhood Hits	905	Target Neighborhood Hits	700	Shared Neighborhood Hits	385
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

LAMA5_MOUSE
NC score	0.595911 (rank : 113)	θ value	3.28125e-26 (rank : 70)
Query Neighborhood Hits	905	Target Neighborhood Hits	828	Shared Neighborhood Hits	398
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

EMR2_HUMAN
NC score	0.594158 (rank : 114)	θ value	1.2077e-20 (rank : 104)
Query Neighborhood Hits	905	Target Neighborhood Hits	345	Shared Neighborhood Hits	266
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

ZAN_MOUSE
NC score	0.592799 (rank : 115)	θ value	3.39556e-23 (rank : 80)
Query Neighborhood Hits	905	Target Neighborhood Hits	808	Shared Neighborhood Hits	435
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

SLIT2_HUMAN
NC score	0.592404 (rank : 116)	θ value	1.46268e-50 (rank : 39)
Query Neighborhood Hits	905	Target Neighborhood Hits	708	Shared Neighborhood Hits	398
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

COMP_HUMAN
NC score	0.591114 (rank : 117)	θ value	9.26847e-13 (rank : 204)
Query Neighborhood Hits	905	Target Neighborhood Hits	258	Shared Neighborhood Hits	238
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

KR107_HUMAN
NC score	0.589464 (rank : 118)	θ value	2.69671e-12 (rank : 213)
Query Neighborhood Hits	905	Target Neighborhood Hits	330	Shared Neighborhood Hits	264
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

EMR1_MOUSE
NC score	0.588726 (rank : 119)	θ value	1.12775e-26 (rank : 67)
Query Neighborhood Hits	905	Target Neighborhood Hits	349	Shared Neighborhood Hits	263
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

SLIT2_MOUSE
NC score	0.587051 (rank : 120)	θ value	1.61718e-49 (rank : 42)
Query Neighborhood Hits	905	Target Neighborhood Hits	684	Shared Neighborhood Hits	375
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CD97_HUMAN
NC score	0.585931 (rank : 121)	θ value	7.82807e-20 (rank : 113)
Query Neighborhood Hits	905	Target Neighborhood Hits	353	Shared Neighborhood Hits	268
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

KR106_HUMAN
NC score	0.584509 (rank : 122)	θ value	5.43371e-13 (rank : 199)
Query Neighborhood Hits	905	Target Neighborhood Hits	347	Shared Neighborhood Hits	271
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

LAMA5_HUMAN
NC score	0.584226 (rank : 123)	θ value	1.57365e-28 (rank : 64)
Query Neighborhood Hits	905	Target Neighborhood Hits	976	Shared Neighborhood Hits	399
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

KR104_HUMAN
NC score	0.581801 (rank : 124)	θ value	4.59992e-12 (rank : 219)
Query Neighborhood Hits	905	Target Neighborhood Hits	313	Shared Neighborhood Hits	249
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KRA58_HUMAN
NC score	0.579264 (rank : 125)	θ value	0.00509761 (rank : 557)
Query Neighborhood Hits	905	Target Neighborhood Hits	324	Shared Neighborhood Hits	250
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

SLIT3_MOUSE
NC score	0.578513 (rank : 126)	θ value	5.7518e-47 (rank : 45)
Query Neighborhood Hits	905	Target Neighborhood Hits	700	Shared Neighborhood Hits	381
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TSP3_MOUSE
NC score	0.576437 (rank : 127)	θ value	2.60593e-15 (rank : 168)
Query Neighborhood Hits	905	Target Neighborhood Hits	247	Shared Neighborhood Hits	222
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

SLIT3_HUMAN
NC score	0.571383 (rank : 128)	θ value	3.15612e-45 (rank : 48)
Query Neighborhood Hits	905	Target Neighborhood Hits	682	Shared Neighborhood Hits	362
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

MEGF9_HUMAN
NC score	0.569424 (rank : 129)	θ value	4.45536e-07 (rank : 391)
Query Neighborhood Hits	905	Target Neighborhood Hits	557	Shared Neighborhood Hits	299
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

TSP3_HUMAN
NC score	0.567941 (rank : 130)	θ value	5.43371e-13 (rank : 201)
Query Neighborhood Hits	905	Target Neighborhood Hits	250	Shared Neighborhood Hits	219
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

NAGPA_HUMAN
NC score	0.564428 (rank : 131)	θ value	1.99992e-07 (rank : 370)
Query Neighborhood Hits	905	Target Neighborhood Hits	282	Shared Neighborhood Hits	264
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LAMB2_HUMAN
NC score	0.562667 (rank : 132)	θ value	2.69047e-20 (rank : 110)
Query Neighborhood Hits	905	Target Neighborhood Hits	692	Shared Neighborhood Hits	335
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMA1_MOUSE
NC score	0.558856 (rank : 133)	θ value	6.40375e-22 (rank : 93)
Query Neighborhood Hits	905	Target Neighborhood Hits	838	Shared Neighborhood Hits	358
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NAGPA_MOUSE
NC score	0.558465 (rank : 134)	θ value	9.92553e-07 (rank : 402)
Query Neighborhood Hits	905	Target Neighborhood Hits	308	Shared Neighborhood Hits	287
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LAMA1_HUMAN
NC score	0.556890 (rank : 135)	θ value	2.69047e-20 (rank : 109)
Query Neighborhood Hits	905	Target Neighborhood Hits	804	Shared Neighborhood Hits	349
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB2_MOUSE
NC score	0.556796 (rank : 136)	θ value	9.24701e-21 (rank : 102)
Query Neighborhood Hits	905	Target Neighborhood Hits	722	Shared Neighborhood Hits	324
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMC3_MOUSE
NC score	0.551429 (rank : 137)	θ value	7.32683e-18 (rank : 129)
Query Neighborhood Hits	905	Target Neighborhood Hits	624	Shared Neighborhood Hits	327
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LRP2_HUMAN
NC score	0.548891 (rank : 138)	θ value	7.09661e-13 (rank : 203)
Query Neighborhood Hits	905	Target Neighborhood Hits	573	Shared Neighborhood Hits	435
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LAMC3_HUMAN
NC score	0.544141 (rank : 139)	θ value	9.56915e-18 (rank : 133)
Query Neighborhood Hits	905	Target Neighborhood Hits	588	Shared Neighborhood Hits	329
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LDLR_HUMAN
NC score	0.537804 (rank : 140)	θ value	1.9326e-10 (rank : 266)
Query Neighborhood Hits	905	Target Neighborhood Hits	375	Shared Neighborhood Hits	313
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MEGF9_MOUSE
NC score	0.535836 (rank : 141)	θ value	1.38499e-08 (rank : 332)
Query Neighborhood Hits	905	Target Neighborhood Hits	896	Shared Neighborhood Hits	288
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CD248_MOUSE
NC score	0.534297 (rank : 142)	θ value	1.43324e-05 (rank : 436)
Query Neighborhood Hits	905	Target Neighborhood Hits	578	Shared Neighborhood Hits	246
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

LAMC2_MOUSE
NC score	0.532763 (rank : 143)	θ value	1.58096e-12 (rank : 208)
Query Neighborhood Hits	905	Target Neighborhood Hits	614	Shared Neighborhood Hits	299
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

CD248_HUMAN
NC score	0.530335 (rank : 144)	θ value	3.19293e-05 (rank : 450)
Query Neighborhood Hits	905	Target Neighborhood Hits	679	Shared Neighborhood Hits	266
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

VLDLR_HUMAN
NC score	0.529613 (rank : 145)	θ value	8.11959e-09 (rank : 328)
Query Neighborhood Hits	905	Target Neighborhood Hits	383	Shared Neighborhood Hits	306
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

KRA57_HUMAN
NC score	0.528814 (rank : 146)	θ value	0.00228821 (rank : 535)
Query Neighborhood Hits	905	Target Neighborhood Hits	269	Shared Neighborhood Hits	216
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

VLDLR_MOUSE
NC score	0.527442 (rank : 147)	θ value	3.08544e-08 (rank : 341)
Query Neighborhood Hits	905	Target Neighborhood Hits	360	Shared Neighborhood Hits	295
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

KRA59_HUMAN
NC score	0.527343 (rank : 148)	θ value	0.125558 (rank : 661)
Query Neighborhood Hits	905	Target Neighborhood Hits	310	Shared Neighborhood Hits	233
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

HHIP_HUMAN
NC score	0.526514 (rank : 149)	θ value	0.000121331 (rank : 467)
Query Neighborhood Hits	905	Target Neighborhood Hits	249	Shared Neighborhood Hits	237
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

MATN4_HUMAN
NC score	0.522878 (rank : 150)	θ value	7.34386e-10 (rank : 292)
Query Neighborhood Hits	905	Target Neighborhood Hits	287	Shared Neighborhood Hits	239
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

LAMA2_HUMAN
NC score	0.522516 (rank : 151)	θ value	7.56453e-23 (rank : 83)
Query Neighborhood Hits	905	Target Neighborhood Hits	1092	Shared Neighborhood Hits	359
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB1_MOUSE
NC score	0.522093 (rank : 152)	θ value	9.54697e-26 (rank : 72)
Query Neighborhood Hits	905	Target Neighborhood Hits	919	Shared Neighborhood Hits	321
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MATN3_MOUSE
NC score	0.521927 (rank : 153)	θ value	5.81887e-07 (rank : 395)
Query Neighborhood Hits	905	Target Neighborhood Hits	261	Shared Neighborhood Hits	217
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

LRP8_MOUSE
NC score	0.521780 (rank : 154)	θ value	9.59137e-10 (rank : 301)
Query Neighborhood Hits	905	Target Neighborhood Hits	385	Shared Neighborhood Hits	302
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MATN3_HUMAN
NC score	0.519505 (rank : 155)	θ value	1.53129e-07 (rank : 365)
Query Neighborhood Hits	905	Target Neighborhood Hits	268	Shared Neighborhood Hits	211
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

KRA55_HUMAN
NC score	0.518323 (rank : 156)	θ value	0.0252991 (rank : 603)
Query Neighborhood Hits	905	Target Neighborhood Hits	257	Shared Neighborhood Hits	209
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

GRN_MOUSE
NC score	0.517569 (rank : 157)	θ value	3.52202e-12 (rank : 214)
Query Neighborhood Hits	905	Target Neighborhood Hits	248	Shared Neighborhood Hits	214
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

PROZ_MOUSE
NC score	0.515702 (rank : 158)	θ value	5.26297e-08 (rank : 352)
Query Neighborhood Hits	905	Target Neighborhood Hits	410	Shared Neighborhood Hits	268
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

LAMC2_HUMAN
NC score	0.513679 (rank : 159)	θ value	7.09661e-13 (rank : 202)
Query Neighborhood Hits	905	Target Neighborhood Hits	715	Shared Neighborhood Hits	298
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LDLR_MOUSE
NC score	0.513035 (rank : 160)	θ value	2.36244e-08 (rank : 338)
Query Neighborhood Hits	905	Target Neighborhood Hits	382	Shared Neighborhood Hits	310
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

PROZ_HUMAN
NC score	0.511447 (rank : 161)	θ value	1.17247e-07 (rank : 361)
Query Neighborhood Hits	905	Target Neighborhood Hits	422	Shared Neighborhood Hits	276
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

KRA54_HUMAN
NC score	0.511362 (rank : 162)	θ value	2.21117e-06 (rank : 413)
Query Neighborhood Hits	905	Target Neighborhood Hits	270	Shared Neighborhood Hits	207
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LAMC1_MOUSE
NC score	0.510116 (rank : 163)	θ value	6.20254e-17 (rank : 149)
Query Neighborhood Hits	905	Target Neighborhood Hits	856	Shared Neighborhood Hits	322
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

GRN_HUMAN
NC score	0.509782 (rank : 164)	θ value	1.133e-10 (rank : 255)
Query Neighborhood Hits	905	Target Neighborhood Hits	268	Shared Neighborhood Hits	222
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

CD97_MOUSE
NC score	0.509437 (rank : 165)	θ value	6.41864e-14 (rank : 182)
Query Neighborhood Hits	905	Target Neighborhood Hits	295	Shared Neighborhood Hits	221
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

KR101_HUMAN
NC score	0.507357 (rank : 166)	θ value	5.26297e-08 (rank : 349)
Query Neighborhood Hits	905	Target Neighborhood Hits	261	Shared Neighborhood Hits	203
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

HHIP_MOUSE
NC score	0.506651 (rank : 167)	θ value	0.000158464 (rank : 470)
Query Neighborhood Hits	905	Target Neighborhood Hits	219	Shared Neighborhood Hits	208
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

PSD10_HUMAN
NC score	0.505055 (rank : 168)	θ value	1.80466e-16 (rank : 154)
Query Neighborhood Hits	905	Target Neighborhood Hits	301	Shared Neighborhood Hits	289
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

NTNG2_MOUSE
NC score	0.504984 (rank : 169)	θ value	2.44474e-05 (rank : 448)
Query Neighborhood Hits	905	Target Neighborhood Hits	276	Shared Neighborhood Hits	255
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMB1_HUMAN
NC score	0.504481 (rank : 170)	θ value	1.42661e-21 (rank : 94)
Query Neighborhood Hits	905	Target Neighborhood Hits	1018	Shared Neighborhood Hits	338
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LRP8_HUMAN
NC score	0.503755 (rank : 171)	θ value	2.79066e-09 (rank : 320)
Query Neighborhood Hits	905	Target Neighborhood Hits	346	Shared Neighborhood Hits	274
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

CSPG2_MOUSE
NC score	0.503524 (rank : 172)	θ value	3.28887e-18 (rank : 125)
Query Neighborhood Hits	905	Target Neighborhood Hits	711	Shared Neighborhood Hits	299
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

PSD10_MOUSE
NC score	0.503224 (rank : 173)	θ value	1.99529e-15 (rank : 166)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	287
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANKR6_HUMAN
NC score	0.499820 (rank : 174)	θ value	2.7842e-17 (rank : 140)
Query Neighborhood Hits	905	Target Neighborhood Hits	439	Shared Neighborhood Hits	293
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

LAMB3_MOUSE
NC score	0.499671 (rank : 175)	θ value	1.25267e-09 (rank : 310)
Query Neighborhood Hits	905	Target Neighborhood Hits	444	Shared Neighborhood Hits	254
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

CSPG2_HUMAN
NC score	0.498719 (rank : 176)	θ value	2.5182e-18 (rank : 123)
Query Neighborhood Hits	905	Target Neighborhood Hits	681	Shared Neighborhood Hits	288
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

LAMA2_MOUSE
NC score	0.498434 (rank : 177)	θ value	2.59989e-23 (rank : 79)
Query Neighborhood Hits	905	Target Neighborhood Hits	1198	Shared Neighborhood Hits	365
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC1_HUMAN
NC score	0.496802 (rank : 178)	θ value	2.7842e-17 (rank : 142)
Query Neighborhood Hits	905	Target Neighborhood Hits	922	Shared Neighborhood Hits	328
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

ELTD1_MOUSE
NC score	0.495726 (rank : 179)	θ value	3.89403e-11 (rank : 243)
Query Neighborhood Hits	905	Target Neighborhood Hits	288	Shared Neighborhood Hits	215
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

ANR29_HUMAN
NC score	0.495636 (rank : 180)	θ value	4.59992e-12 (rank : 217)
Query Neighborhood Hits	905	Target Neighborhood Hits	294	Shared Neighborhood Hits	282
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

NTNG2_HUMAN
NC score	0.494694 (rank : 181)	θ value	2.61198e-07 (rank : 377)
Query Neighborhood Hits	905	Target Neighborhood Hits	276	Shared Neighborhood Hits	251
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

BCL3_HUMAN
NC score	0.494403 (rank : 182)	θ value	4.91457e-14 (rank : 179)
Query Neighborhood Hits	905	Target Neighborhood Hits	324	Shared Neighborhood Hits	283
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

MATN4_MOUSE
NC score	0.494304 (rank : 183)	θ value	5.26297e-08 (rank : 350)
Query Neighborhood Hits	905	Target Neighborhood Hits	277	Shared Neighborhood Hits	229
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

ANR50_HUMAN
NC score	0.494266 (rank : 184)	θ value	1.63225e-17 (rank : 135)
Query Neighborhood Hits	905	Target Neighborhood Hits	361	Shared Neighborhood Hits	295
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

CSPG3_MOUSE
NC score	0.492920 (rank : 185)	θ value	2.13179e-17 (rank : 138)
Query Neighborhood Hits	905	Target Neighborhood Hits	657	Shared Neighborhood Hits	291
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ANR23_HUMAN
NC score	0.492207 (rank : 186)	θ value	4.91457e-14 (rank : 178)
Query Neighborhood Hits	905	Target Neighborhood Hits	291	Shared Neighborhood Hits	284
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

BCL3_MOUSE
NC score	0.489677 (rank : 187)	θ value	1.58096e-12 (rank : 207)
Query Neighborhood Hits	905	Target Neighborhood Hits	388	Shared Neighborhood Hits	290
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ASB8_HUMAN
NC score	0.489444 (rank : 188)	θ value	7.84624e-12 (rank : 225)
Query Neighborhood Hits	905	Target Neighborhood Hits	294	Shared Neighborhood Hits	283
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
NC score	0.489025 (rank : 189)	θ value	7.84624e-12 (rank : 226)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	280
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB16_MOUSE
NC score	0.488775 (rank : 190)	θ value	3.28887e-18 (rank : 124)
Query Neighborhood Hits	905	Target Neighborhood Hits	306	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ITB6_MOUSE
NC score	0.487708 (rank : 191)	θ value	3.29651e-10 (rank : 274)
Query Neighborhood Hits	905	Target Neighborhood Hits	341	Shared Neighborhood Hits	283
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ASB3_HUMAN
NC score	0.486525 (rank : 192)	θ value	1.42992e-13 (rank : 189)
Query Neighborhood Hits	905	Target Neighborhood Hits	316	Shared Neighborhood Hits	289
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

LAMA3_MOUSE
NC score	0.486275 (rank : 193)	θ value	6.41864e-14 (rank : 183)
Query Neighborhood Hits	905	Target Neighborhood Hits	859	Shared Neighborhood Hits	351
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

CSPG3_HUMAN
NC score	0.485715 (rank : 194)	θ value	2.7842e-17 (rank : 141)
Query Neighborhood Hits	905	Target Neighborhood Hits	676	Shared Neighborhood Hits	275
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ANR44_HUMAN
NC score	0.485684 (rank : 195)	θ value	7.32683e-18 (rank : 128)
Query Neighborhood Hits	905	Target Neighborhood Hits	318	Shared Neighborhood Hits	294
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR23_MOUSE
NC score	0.485523 (rank : 196)	θ value	6.00763e-12 (rank : 220)
Query Neighborhood Hits	905	Target Neighborhood Hits	296	Shared Neighborhood Hits	283
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR28_MOUSE
NC score	0.484982 (rank : 197)	θ value	6.62687e-19 (rank : 118)
Query Neighborhood Hits	905	Target Neighborhood Hits	314	Shared Neighborhood Hits	295
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR16_HUMAN
NC score	0.484338 (rank : 198)	θ value	1.63604e-09 (rank : 312)
Query Neighborhood Hits	905	Target Neighborhood Hits	286	Shared Neighborhood Hits	278
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR28_HUMAN
NC score	0.482707 (rank : 199)	θ value	7.32683e-18 (rank : 127)
Query Neighborhood Hits	905	Target Neighborhood Hits	314	Shared Neighborhood Hits	295
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ASB10_MOUSE
NC score	0.482596 (rank : 200)	θ value	1.80466e-16 (rank : 153)
Query Neighborhood Hits	905	Target Neighborhood Hits	301	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

GABP3_MOUSE
NC score	0.482366 (rank : 201)	θ value	2.52405e-10 (rank : 269)
Query Neighborhood Hits	905	Target Neighborhood Hits	330	Shared Neighborhood Hits	276
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

GABP2_MOUSE
NC score	0.481831 (rank : 202)	θ value	7.84624e-12 (rank : 228)
Query Neighborhood Hits	905	Target Neighborhood Hits	429	Shared Neighborhood Hits	281
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ASB3_MOUSE
NC score	0.481493 (rank : 203)	θ value	6.00763e-12 (rank : 222)
Query Neighborhood Hits	905	Target Neighborhood Hits	316	Shared Neighborhood Hits	288
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB2_HUMAN
NC score	0.481120 (rank : 204)	θ value	9.90251e-15 (rank : 173)
Query Neighborhood Hits	905	Target Neighborhood Hits	309	Shared Neighborhood Hits	283
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANK1_MOUSE
NC score	0.481114 (rank : 205)	θ value	1.2077e-20 (rank : 103)
Query Neighborhood Hits	905	Target Neighborhood Hits	430	Shared Neighborhood Hits	294
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

GABP2_HUMAN
NC score	0.481021 (rank : 206)	θ value	7.84624e-12 (rank : 227)
Query Neighborhood Hits	905	Target Neighborhood Hits	454	Shared Neighborhood Hits	281
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

PA2G6_MOUSE
NC score	0.480716 (rank : 207)	θ value	2.0648e-12 (rank : 211)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	284
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANR52_MOUSE
NC score	0.480620 (rank : 208)	θ value	1.16975e-15 (rank : 161)
Query Neighborhood Hits	905	Target Neighborhood Hits	318	Shared Neighborhood Hits	293
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
NC score	0.480014 (rank : 209)	θ value	1.99529e-15 (rank : 165)
Query Neighborhood Hits	905	Target Neighborhood Hits	322	Shared Neighborhood Hits	293
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANK1_HUMAN
NC score	0.479894 (rank : 210)	θ value	2.69047e-20 (rank : 108)
Query Neighborhood Hits	905	Target Neighborhood Hits	416	Shared Neighborhood Hits	297
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

FANK1_HUMAN
NC score	0.479682 (rank : 211)	θ value	9.59137e-10 (rank : 300)
Query Neighborhood Hits	905	Target Neighborhood Hits	326	Shared Neighborhood Hits	285
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

PA2G6_HUMAN
NC score	0.478694 (rank : 212)	θ value	1.9326e-10 (rank : 267)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	278
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

TNKS2_HUMAN
NC score	0.478427 (rank : 213)	θ value	2.60593e-15 (rank : 167)
Query Neighborhood Hits	905	Target Neighborhood Hits	361	Shared Neighborhood Hits	294
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ASB10_HUMAN
NC score	0.478322 (rank : 214)	θ value	1.58096e-12 (rank : 206)
Query Neighborhood Hits	905	Target Neighborhood Hits	291	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ANKR1_HUMAN
NC score	0.478028 (rank : 215)	θ value	1.9326e-10 (rank : 262)
Query Neighborhood Hits	905	Target Neighborhood Hits	308	Shared Neighborhood Hits	278
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

INVS_HUMAN
NC score	0.477985 (rank : 216)	θ value	1.33837e-11 (rank : 232)
Query Neighborhood Hits	905	Target Neighborhood Hits	455	Shared Neighborhood Hits	290
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ASB2_MOUSE
NC score	0.477957 (rank : 217)	θ value	2.43908e-13 (rank : 195)
Query Neighborhood Hits	905	Target Neighborhood Hits	321	Shared Neighborhood Hits	281
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANK3_HUMAN
NC score	0.477526 (rank : 218)	θ value	5.79196e-23 (rank : 82)
Query Neighborhood Hits	905	Target Neighborhood Hits	853	Shared Neighborhood Hits	310
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

TNKS1_HUMAN
NC score	0.477122 (rank : 219)	θ value	4.44505e-15 (rank : 171)
Query Neighborhood Hits	905	Target Neighborhood Hits	477	Shared Neighborhood Hits	306
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

LRP4_MOUSE
NC score	0.477119 (rank : 220)	θ value	7.34386e-10 (rank : 291)
Query Neighborhood Hits	905	Target Neighborhood Hits	351	Shared Neighborhood Hits	286
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

KR102_HUMAN
NC score	0.476626 (rank : 221)	θ value	4.92598e-06 (rank : 420)
Query Neighborhood Hits	905	Target Neighborhood Hits	264	Shared Neighborhood Hits	216
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

ANKR2_MOUSE
NC score	0.476321 (rank : 222)	θ value	1.47974e-10 (rank : 259)
Query Neighborhood Hits	905	Target Neighborhood Hits	312	Shared Neighborhood Hits	286
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKR1_MOUSE
NC score	0.476205 (rank : 223)	θ value	1.9326e-10 (rank : 263)
Query Neighborhood Hits	905	Target Neighborhood Hits	316	Shared Neighborhood Hits	284
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

IKBA_HUMAN
NC score	0.475769 (rank : 224)	θ value	1.47974e-10 (rank : 261)
Query Neighborhood Hits	905	Target Neighborhood Hits	280	Shared Neighborhood Hits	275
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ANR49_MOUSE
NC score	0.474377 (rank : 225)	θ value	3.29651e-10 (rank : 272)
Query Neighborhood Hits	905	Target Neighborhood Hits	285	Shared Neighborhood Hits	273
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR49_HUMAN
NC score	0.474249 (rank : 226)	θ value	5.62301e-10 (rank : 279)
Query Neighborhood Hits	905	Target Neighborhood Hits	282	Shared Neighborhood Hits	272
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ASB7_HUMAN
NC score	0.473628 (rank : 227)	θ value	7.34386e-10 (rank : 288)
Query Neighborhood Hits	905	Target Neighborhood Hits	296	Shared Neighborhood Hits	280
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

INVS_MOUSE
NC score	0.473579 (rank : 228)	θ value	2.28291e-11 (rank : 237)
Query Neighborhood Hits	905	Target Neighborhood Hits	609	Shared Neighborhood Hits	297
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ASB7_MOUSE
NC score	0.473574 (rank : 229)	θ value	7.34386e-10 (rank : 289)
Query Neighborhood Hits	905	Target Neighborhood Hits	296	Shared Neighborhood Hits	280
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

FANK1_MOUSE
NC score	0.473549 (rank : 230)	θ value	3.64472e-09 (rank : 321)
Query Neighborhood Hits	905	Target Neighborhood Hits	325	Shared Neighborhood Hits	284
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

LRP4_HUMAN
NC score	0.473477 (rank : 231)	θ value	1.63604e-09 (rank : 314)
Query Neighborhood Hits	905	Target Neighborhood Hits	355	Shared Neighborhood Hits	288
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

TRPA1_MOUSE
NC score	0.473270 (rank : 232)	θ value	8.95645e-16 (rank : 160)
Query Neighborhood Hits	905	Target Neighborhood Hits	343	Shared Neighborhood Hits	291
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

USH2A_MOUSE
NC score	0.473175 (rank : 233)	θ value	1.86753e-13 (rank : 194)
Query Neighborhood Hits	905	Target Neighborhood Hits	626	Shared Neighborhood Hits	310
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

ANKR2_HUMAN
NC score	0.472613 (rank : 234)	θ value	9.59137e-10 (rank : 296)
Query Neighborhood Hits	905	Target Neighborhood Hits	321	Shared Neighborhood Hits	287
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ASZ1_MOUSE
NC score	0.472537 (rank : 235)	θ value	6.64225e-11 (rank : 252)
Query Neighborhood Hits	905	Target Neighborhood Hits	319	Shared Neighborhood Hits	275
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB16_HUMAN
NC score	0.472373 (rank : 236)	θ value	1.02475e-11 (rank : 229)
Query Neighborhood Hits	905	Target Neighborhood Hits	286	Shared Neighborhood Hits	272
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

NTNG1_MOUSE
NC score	0.471548 (rank : 237)	θ value	3.41135e-07 (rank : 382)
Query Neighborhood Hits	905	Target Neighborhood Hits	246	Shared Neighborhood Hits	217
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

ANR39_HUMAN
NC score	0.471442 (rank : 238)	θ value	8.97725e-08 (rank : 356)
Query Neighborhood Hits	905	Target Neighborhood Hits	285	Shared Neighborhood Hits	279
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

NTNG1_HUMAN
NC score	0.471330 (rank : 239)	θ value	3.41135e-07 (rank : 381)
Query Neighborhood Hits	905	Target Neighborhood Hits	247	Shared Neighborhood Hits	215
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

KR171_HUMAN
NC score	0.471196 (rank : 240)	θ value	0.813845 (rank : 746)
Query Neighborhood Hits	905	Target Neighborhood Hits	144	Shared Neighborhood Hits	124
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

ITB6_HUMAN
NC score	0.471027 (rank : 241)	θ value	1.9326e-10 (rank : 265)
Query Neighborhood Hits	905	Target Neighborhood Hits	318	Shared Neighborhood Hits	270
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

IKBE_MOUSE
NC score	0.470618 (rank : 242)	θ value	1.9326e-10 (rank : 264)
Query Neighborhood Hits	905	Target Neighborhood Hits	308	Shared Neighborhood Hits	280
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANR42_MOUSE
NC score	0.470097 (rank : 243)	θ value	5.08577e-11 (rank : 247)
Query Neighborhood Hits	905	Target Neighborhood Hits	334	Shared Neighborhood Hits	282
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

IKBA_MOUSE
NC score	0.469287 (rank : 244)	θ value	1.133e-10 (rank : 256)
Query Neighborhood Hits	905	Target Neighborhood Hits	283	Shared Neighborhood Hits	276
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

LAMB3_HUMAN
NC score	0.468880 (rank : 245)	θ value	2.13673e-09 (rank : 317)
Query Neighborhood Hits	905	Target Neighborhood Hits	461	Shared Neighborhood Hits	227
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

CDN2C_HUMAN
NC score	0.468814 (rank : 246)	θ value	5.81887e-07 (rank : 392)
Query Neighborhood Hits	905	Target Neighborhood Hits	262	Shared Neighborhood Hits	259
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

TRPA1_HUMAN
NC score	0.468803 (rank : 247)	θ value	1.58096e-12 (rank : 210)
Query Neighborhood Hits	905	Target Neighborhood Hits	339	Shared Neighborhood Hits	291
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ITB5_MOUSE
NC score	0.467956 (rank : 248)	θ value	1.17247e-07 (rank : 359)
Query Neighborhood Hits	905	Target Neighborhood Hits	329	Shared Neighborhood Hits	283
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ANKS3_HUMAN
NC score	0.467870 (rank : 249)	θ value	1.47974e-10 (rank : 260)
Query Neighborhood Hits	905	Target Neighborhood Hits	355	Shared Neighborhood Hits	272
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASZ1_HUMAN
NC score	0.467570 (rank : 250)	θ value	2.13673e-09 (rank : 316)
Query Neighborhood Hits	905	Target Neighborhood Hits	341	Shared Neighborhood Hits	274
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

IKBE_HUMAN
NC score	0.467410 (rank : 251)	θ value	1.33837e-11 (rank : 231)
Query Neighborhood Hits	905	Target Neighborhood Hits	288	Shared Neighborhood Hits	268
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ANKS3_MOUSE
NC score	0.466831 (rank : 252)	θ value	3.89403e-11 (rank : 241)
Query Neighborhood Hits	905	Target Neighborhood Hits	355	Shared Neighborhood Hits	273
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

KR105_HUMAN
NC score	0.466802 (rank : 253)	θ value	1.43324e-05 (rank : 438)
Query Neighborhood Hits	905	Target Neighborhood Hits	271	Shared Neighborhood Hits	217
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

PP16A_MOUSE
NC score	0.465983 (rank : 254)	θ value	5.62301e-10 (rank : 283)
Query Neighborhood Hits	905	Target Neighborhood Hits	318	Shared Neighborhood Hits	284
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

CDN2D_MOUSE
NC score	0.465602 (rank : 255)	θ value	5.81887e-07 (rank : 393)
Query Neighborhood Hits	905	Target Neighborhood Hits	267	Shared Neighborhood Hits	262
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANR42_HUMAN
NC score	0.465514 (rank : 256)	θ value	2.61198e-07 (rank : 373)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR39_MOUSE
NC score	0.465355 (rank : 257)	θ value	9.92553e-07 (rank : 398)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANKR7_HUMAN
NC score	0.464864 (rank : 258)	θ value	5.62301e-10 (rank : 278)
Query Neighborhood Hits	905	Target Neighborhood Hits	286	Shared Neighborhood Hits	273
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

AN36B_HUMAN
NC score	0.464756 (rank : 259)	θ value	1.63604e-09 (rank : 311)
Query Neighborhood Hits	905	Target Neighborhood Hits	294	Shared Neighborhood Hits	274
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

CDN2D_HUMAN
NC score	0.464622 (rank : 260)	θ value	1.53129e-07 (rank : 363)
Query Neighborhood Hits	905	Target Neighborhood Hits	268	Shared Neighborhood Hits	262
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

KR511_HUMAN
NC score	0.464330 (rank : 261)	θ value	0.00298849 (rank : 542)
Query Neighborhood Hits	905	Target Neighborhood Hits	231	Shared Neighborhood Hits	181
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

CDN2C_MOUSE
NC score	0.463307 (rank : 262)	θ value	1.69304e-06 (rank : 409)
Query Neighborhood Hits	905	Target Neighborhood Hits	270	Shared Neighborhood Hits	264
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

MYPT1_MOUSE
NC score	0.462886 (rank : 263)	θ value	6.64225e-11 (rank : 253)
Query Neighborhood Hits	905	Target Neighborhood Hits	539	Shared Neighborhood Hits	290
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ASB13_MOUSE
NC score	0.462884 (rank : 264)	θ value	9.59137e-10 (rank : 298)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	281
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

CRIM1_HUMAN
NC score	0.462747 (rank : 265)	θ value	2.36244e-08 (rank : 337)
Query Neighborhood Hits	905	Target Neighborhood Hits	362	Shared Neighborhood Hits	251
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

ASB15_HUMAN
NC score	0.462297 (rank : 266)	θ value	5.08577e-11 (rank : 248)
Query Neighborhood Hits	905	Target Neighborhood Hits	305	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB13_HUMAN
NC score	0.461777 (rank : 267)	θ value	7.34386e-10 (rank : 287)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	283
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ANKS1_HUMAN
NC score	0.461412 (rank : 268)	θ value	1.74796e-11 (rank : 235)
Query Neighborhood Hits	905	Target Neighborhood Hits	438	Shared Neighborhood Hits	297
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ASB14_MOUSE
NC score	0.460077 (rank : 269)	θ value	6.43352e-06 (rank : 421)
Query Neighborhood Hits	905	Target Neighborhood Hits	293	Shared Neighborhood Hits	274
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

TSP1_MOUSE
NC score	0.458968 (rank : 270)	θ value	4.91457e-14 (rank : 181)
Query Neighborhood Hits	905	Target Neighborhood Hits	396	Shared Neighborhood Hits	275
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

PP16A_HUMAN
NC score	0.458557 (rank : 271)	θ value	1.9326e-10 (rank : 268)
Query Neighborhood Hits	905	Target Neighborhood Hits	340	Shared Neighborhood Hits	278
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

MIB1_HUMAN
NC score	0.458458 (rank : 272)	θ value	2.98157e-11 (rank : 239)
Query Neighborhood Hits	905	Target Neighborhood Hits	470	Shared Neighborhood Hits	297
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB2_HUMAN
NC score	0.458452 (rank : 273)	θ value	2.20605e-14 (rank : 176)
Query Neighborhood Hits	905	Target Neighborhood Hits	438	Shared Neighborhood Hits	292
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MIB1_MOUSE
NC score	0.457633 (rank : 274)	θ value	2.98157e-11 (rank : 240)
Query Neighborhood Hits	905	Target Neighborhood Hits	471	Shared Neighborhood Hits	296
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

CT086_HUMAN
NC score	0.457105 (rank : 275)	θ value	0.000786445 (rank : 501)
Query Neighborhood Hits	905	Target Neighborhood Hits	277	Shared Neighborhood Hits	269
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

EHMT2_HUMAN
NC score	0.457029 (rank : 276)	θ value	2.97466e-19 (rank : 117)
Query Neighborhood Hits	905	Target Neighborhood Hits	498	Shared Neighborhood Hits	306
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

RN5A_HUMAN
NC score	0.456918 (rank : 277)	θ value	2.13673e-09 (rank : 318)
Query Neighborhood Hits	905	Target Neighborhood Hits	608	Shared Neighborhood Hits	281
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

MYPT2_HUMAN
NC score	0.456819 (rank : 278)	θ value	6.00763e-12 (rank : 224)
Query Neighborhood Hits	905	Target Neighborhood Hits	707	Shared Neighborhood Hits	293
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

TSP1_HUMAN
NC score	0.455652 (rank : 279)	θ value	3.18553e-13 (rank : 198)
Query Neighborhood Hits	905	Target Neighborhood Hits	389	Shared Neighborhood Hits	270
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

ANKS6_MOUSE
NC score	0.455594 (rank : 280)	θ value	4.0297e-08 (rank : 343)
Query Neighborhood Hits	905	Target Neighborhood Hits	435	Shared Neighborhood Hits	289
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

CSKI1_MOUSE
NC score	0.455140 (rank : 281)	θ value	6.20254e-17 (rank : 146)
Query Neighborhood Hits	905	Target Neighborhood Hits	1031	Shared Neighborhood Hits	332
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ITB5_HUMAN
NC score	0.454589 (rank : 282)	θ value	5.81887e-07 (rank : 394)
Query Neighborhood Hits	905	Target Neighborhood Hits	310	Shared Neighborhood Hits	264
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ANR46_HUMAN
NC score	0.453951 (rank : 283)	θ value	0.000158464 (rank : 469)
Query Neighborhood Hits	905	Target Neighborhood Hits	281	Shared Neighborhood Hits	273
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

EHMT1_HUMAN
NC score	0.453652 (rank : 284)	θ value	6.85773e-16 (rank : 158)
Query Neighborhood Hits	905	Target Neighborhood Hits	417	Shared Neighborhood Hits	290
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ASB15_MOUSE
NC score	0.453550 (rank : 285)	θ value	3.29651e-10 (rank : 273)
Query Neighborhood Hits	905	Target Neighborhood Hits	292	Shared Neighborhood Hits	271
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

PP16B_HUMAN
NC score	0.453176 (rank : 286)	θ value	1.17247e-07 (rank : 360)
Query Neighborhood Hits	905	Target Neighborhood Hits	307	Shared Neighborhood Hits	280
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

CSKI1_HUMAN
NC score	0.452894 (rank : 287)	θ value	4.74913e-17 (rank : 143)
Query Neighborhood Hits	905	Target Neighborhood Hits	997	Shared Neighborhood Hits	328
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANKR5_MOUSE
NC score	0.452881 (rank : 288)	θ value	2.36244e-08 (rank : 335)
Query Neighborhood Hits	905	Target Neighborhood Hits	298	Shared Neighborhood Hits	281
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

MTPN_MOUSE
NC score	0.452663 (rank : 289)	θ value	8.40245e-06 (rank : 428)
Query Neighborhood Hits	905	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

ANKS6_HUMAN
NC score	0.452632 (rank : 290)	θ value	8.97725e-08 (rank : 355)
Query Neighborhood Hits	905	Target Neighborhood Hits	411	Shared Neighborhood Hits	286
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR46_MOUSE
NC score	0.452504 (rank : 291)	θ value	7.1131e-05 (rank : 459)
Query Neighborhood Hits	905	Target Neighborhood Hits	274	Shared Neighborhood Hits	266
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

MYPT1_HUMAN
NC score	0.452279 (rank : 292)	θ value	1.74796e-11 (rank : 236)
Query Neighborhood Hits	905	Target Neighborhood Hits	723	Shared Neighborhood Hits	294
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ANR35_HUMAN
NC score	0.452172 (rank : 293)	θ value	6.00763e-12 (rank : 221)
Query Neighborhood Hits	905	Target Neighborhood Hits	784	Shared Neighborhood Hits	306
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

PP16B_MOUSE
NC score	0.451637 (rank : 294)	θ value	3.41135e-07 (rank : 383)
Query Neighborhood Hits	905	Target Neighborhood Hits	302	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ITB3_HUMAN
NC score	0.451625 (rank : 295)	θ value	9.92553e-07 (rank : 401)
Query Neighborhood Hits	905	Target Neighborhood Hits	325	Shared Neighborhood Hits	283
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

MTPN_HUMAN
NC score	0.450925 (rank : 296)	θ value	8.40245e-06 (rank : 427)
Query Neighborhood Hits	905	Target Neighborhood Hits	269	Shared Neighborhood Hits	264
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ANKS1_MOUSE
NC score	0.450029 (rank : 297)	θ value	1.25267e-09 (rank : 307)
Query Neighborhood Hits	905	Target Neighborhood Hits	453	Shared Neighborhood Hits	298
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ITB7_HUMAN
NC score	0.449233 (rank : 298)	θ value	2.61198e-07 (rank : 376)
Query Neighborhood Hits	905	Target Neighborhood Hits	290	Shared Neighborhood Hits	252
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

IKBB_MOUSE
NC score	0.449014 (rank : 299)	θ value	3.64472e-09 (rank : 322)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	279
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

MIB2_MOUSE
NC score	0.448738 (rank : 300)	θ value	2.28291e-11 (rank : 238)
Query Neighborhood Hits	905	Target Neighborhood Hits	409	Shared Neighborhood Hits	284
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

KRA52_HUMAN
NC score	0.448659 (rank : 301)	θ value	0.00298849 (rank : 543)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	190
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

ANR22_HUMAN
NC score	0.448657 (rank : 302)	θ value	1.87187e-05 (rank : 441)
Query Neighborhood Hits	905	Target Neighborhood Hits	243	Shared Neighborhood Hits	241
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

USH2A_HUMAN
NC score	0.448252 (rank : 303)	θ value	3.29651e-10 (rank : 276)
Query Neighborhood Hits	905	Target Neighborhood Hits	600	Shared Neighborhood Hits	284
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

ASB4_MOUSE
NC score	0.448206 (rank : 304)	θ value	1.53129e-07 (rank : 362)
Query Neighborhood Hits	905	Target Neighborhood Hits	265	Shared Neighborhood Hits	258
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ACBD6_MOUSE
NC score	0.447691 (rank : 305)	θ value	3.08544e-08 (rank : 339)
Query Neighborhood Hits	905	Target Neighborhood Hits	305	Shared Neighborhood Hits	280
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

EHMT2_MOUSE
NC score	0.447590 (rank : 306)	θ value	3.28887e-18 (rank : 126)
Query Neighborhood Hits	905	Target Neighborhood Hits	750	Shared Neighborhood Hits	314
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ITB7_MOUSE
NC score	0.447436 (rank : 307)	θ value	1.99992e-07 (rank : 369)
Query Neighborhood Hits	905	Target Neighborhood Hits	277	Shared Neighborhood Hits	242
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB2_MOUSE
NC score	0.446697 (rank : 308)	θ value	1.99992e-07 (rank : 368)
Query Neighborhood Hits	905	Target Neighborhood Hits	326	Shared Neighborhood Hits	283
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ANR10_HUMAN
NC score	0.446426 (rank : 309)	θ value	6.21693e-09 (rank : 326)
Query Neighborhood Hits	905	Target Neighborhood Hits	289	Shared Neighborhood Hits	270
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

IKBB_HUMAN
NC score	0.446032 (rank : 310)	θ value	1.29631e-06 (rank : 406)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	276
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

ANK2_HUMAN
NC score	0.445969 (rank : 311)	θ value	2.20094e-22 (rank : 85)
Query Neighborhood Hits	905	Target Neighborhood Hits	1615	Shared Neighborhood Hits	333
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR19_HUMAN
NC score	0.445873 (rank : 312)	θ value	8.67504e-11 (rank : 254)
Query Neighborhood Hits	905	Target Neighborhood Hits	276	Shared Neighborhood Hits	267
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ACBD6_HUMAN
NC score	0.445847 (rank : 313)	θ value	1.80886e-08 (rank : 334)
Query Neighborhood Hits	905	Target Neighborhood Hits	304	Shared Neighborhood Hits	279
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

CSKI2_MOUSE
NC score	0.445781 (rank : 314)	θ value	3.40345e-15 (rank : 169)
Query Neighborhood Hits	905	Target Neighborhood Hits	812	Shared Neighborhood Hits	309
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB4_HUMAN
NC score	0.445753 (rank : 315)	θ value	1.69304e-06 (rank : 408)
Query Neighborhood Hits	905	Target Neighborhood Hits	264	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

MFGM_MOUSE
NC score	0.445623 (rank : 316)	θ value	2.52405e-10 (rank : 270)
Query Neighborhood Hits	905	Target Neighborhood Hits	233	Shared Neighborhood Hits	207
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

ANR10_MOUSE
NC score	0.445040 (rank : 317)	θ value	7.34386e-10 (rank : 285)
Query Neighborhood Hits	905	Target Neighborhood Hits	273	Shared Neighborhood Hits	268
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANKR5_HUMAN
NC score	0.444962 (rank : 318)	θ value	9.92553e-07 (rank : 397)
Query Neighborhood Hits	905	Target Neighborhood Hits	297	Shared Neighborhood Hits	280
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

CSKI2_HUMAN
NC score	0.444645 (rank : 319)	θ value	8.95645e-16 (rank : 159)
Query Neighborhood Hits	905	Target Neighborhood Hits	747	Shared Neighborhood Hits	316
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PCSK5_MOUSE
NC score	0.441606 (rank : 320)	θ value	1.2105e-12 (rank : 205)
Query Neighborhood Hits	905	Target Neighborhood Hits	613	Shared Neighborhood Hits	347
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

ANR15_HUMAN
NC score	0.440423 (rank : 321)	θ value	1.52774e-15 (rank : 162)
Query Neighborhood Hits	905	Target Neighborhood Hits	478	Shared Neighborhood Hits	263
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

POTE8_HUMAN
NC score	0.440246 (rank : 322)	θ value	1.133e-10 (rank : 257)
Query Neighborhood Hits	905	Target Neighborhood Hits	337	Shared Neighborhood Hits	282
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ANFY1_MOUSE
NC score	0.440007 (rank : 323)	θ value	3.76295e-14 (rank : 177)
Query Neighborhood Hits	905	Target Neighborhood Hits	480	Shared Neighborhood Hits	292
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASB11_HUMAN
NC score	0.439965 (rank : 324)	θ value	4.45536e-07 (rank : 386)
Query Neighborhood Hits	905	Target Neighborhood Hits	271	Shared Neighborhood Hits	258
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANFY1_HUMAN
NC score	0.439785 (rank : 325)	θ value	8.38298e-14 (rank : 184)
Query Neighborhood Hits	905	Target Neighborhood Hits	480	Shared Neighborhood Hits	291
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANRA2_MOUSE
NC score	0.439607 (rank : 326)	θ value	9.29e-05 (rank : 462)
Query Neighborhood Hits	905	Target Neighborhood Hits	287	Shared Neighborhood Hits	271
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB1_HUMAN
NC score	0.438902 (rank : 327)	θ value	2.21117e-06 (rank : 412)
Query Neighborhood Hits	905	Target Neighborhood Hits	291	Shared Neighborhood Hits	269
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB5_HUMAN
NC score	0.437619 (rank : 328)	θ value	2.79066e-09 (rank : 319)
Query Neighborhood Hits	905	Target Neighborhood Hits	283	Shared Neighborhood Hits	268
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANRA2_HUMAN
NC score	0.437600 (rank : 329)	θ value	9.29e-05 (rank : 461)
Query Neighborhood Hits	905	Target Neighborhood Hits	288	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB1_MOUSE
NC score	0.436944 (rank : 330)	θ value	4.92598e-06 (rank : 419)
Query Neighborhood Hits	905	Target Neighborhood Hits	292	Shared Neighborhood Hits	267
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

HMCN1_HUMAN
NC score	0.436349 (rank : 331)	θ value	1.37539e-32 (rank : 59)
Query Neighborhood Hits	905	Target Neighborhood Hits	983	Shared Neighborhood Hits	334
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

AN36A_HUMAN
NC score	0.435398 (rank : 332)	θ value	5.44631e-05 (rank : 456)
Query Neighborhood Hits	905	Target Neighborhood Hits	271	Shared Neighborhood Hits	264
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ASB11_MOUSE
NC score	0.435284 (rank : 333)	θ value	1.69304e-06 (rank : 407)
Query Neighborhood Hits	905	Target Neighborhood Hits	271	Shared Neighborhood Hits	255
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB5_MOUSE
NC score	0.435087 (rank : 334)	θ value	4.76016e-09 (rank : 325)
Query Neighborhood Hits	905	Target Neighborhood Hits	266	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

LAMA4_MOUSE
NC score	0.434505 (rank : 335)	θ value	8.11959e-09 (rank : 327)
Query Neighborhood Hits	905	Target Neighborhood Hits	584	Shared Neighborhood Hits	237
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

ASB12_HUMAN
NC score	0.434245 (rank : 336)	θ value	9.92553e-07 (rank : 399)
Query Neighborhood Hits	905	Target Neighborhood Hits	263	Shared Neighborhood Hits	258
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

KR109_HUMAN
NC score	0.434226 (rank : 337)	θ value	5.44631e-05 (rank : 458)
Query Neighborhood Hits	905	Target Neighborhood Hits	226	Shared Neighborhood Hits	184
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KRA56_HUMAN
NC score	0.434048 (rank : 338)	θ value	0.365318 (rank : 712)
Query Neighborhood Hits	905	Target Neighborhood Hits	207	Shared Neighborhood Hits	169
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

ANR47_MOUSE
NC score	0.432908 (rank : 339)	θ value	3.08544e-08 (rank : 340)
Query Neighborhood Hits	905	Target Neighborhood Hits	350	Shared Neighborhood Hits	260
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

RFXK_HUMAN
NC score	0.432883 (rank : 340)	θ value	9.29e-05 (rank : 464)
Query Neighborhood Hits	905	Target Neighborhood Hits	282	Shared Neighborhood Hits	263
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ANR41_HUMAN
NC score	0.432267 (rank : 341)	θ value	8.40245e-06 (rank : 422)
Query Neighborhood Hits	905	Target Neighborhood Hits	332	Shared Neighborhood Hits	262
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ITB3_MOUSE
NC score	0.432185 (rank : 342)	θ value	1.53129e-07 (rank : 364)
Query Neighborhood Hits	905	Target Neighborhood Hits	319	Shared Neighborhood Hits	275
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

KR108_HUMAN
NC score	0.431963 (rank : 343)	θ value	1.09739e-05 (rank : 433)
Query Neighborhood Hits	905	Target Neighborhood Hits	226	Shared Neighborhood Hits	179
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR10C_HUMAN
NC score	0.431283 (rank : 344)	θ value	2.44474e-05 (rank : 447)
Query Neighborhood Hits	905	Target Neighborhood Hits	219	Shared Neighborhood Hits	181
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

PGBM_MOUSE
NC score	0.431093 (rank : 345)	θ value	7.32683e-18 (rank : 130)
Query Neighborhood Hits	905	Target Neighborhood Hits	1073	Shared Neighborhood Hits	395
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ASB12_MOUSE
NC score	0.430265 (rank : 346)	θ value	1.09739e-05 (rank : 432)
Query Neighborhood Hits	905	Target Neighborhood Hits	261	Shared Neighborhood Hits	255
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB9_HUMAN
NC score	0.429399 (rank : 347)	θ value	2.36244e-08 (rank : 336)
Query Neighborhood Hits	905	Target Neighborhood Hits	267	Shared Neighborhood Hits	253
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

BARD1_HUMAN
NC score	0.429271 (rank : 348)	θ value	9.92553e-07 (rank : 400)
Query Neighborhood Hits	905	Target Neighborhood Hits	427	Shared Neighborhood Hits	284
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

TENR_MOUSE
NC score	0.428611 (rank : 349)	θ value	1.09485e-13 (rank : 188)
Query Neighborhood Hits	905	Target Neighborhood Hits	531	Shared Neighborhood Hits	320
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

USH1G_MOUSE
NC score	0.428308 (rank : 350)	θ value	2.88788e-06 (rank : 416)
Query Neighborhood Hits	905	Target Neighborhood Hits	271	Shared Neighborhood Hits	261
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

USH1G_HUMAN
NC score	0.427893 (rank : 351)	θ value	2.88788e-06 (rank : 415)
Query Neighborhood Hits	905	Target Neighborhood Hits	267	Shared Neighborhood Hits	259
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

RN5A_MOUSE
NC score	0.427790 (rank : 352)	θ value	5.08577e-11 (rank : 249)
Query Neighborhood Hits	905	Target Neighborhood Hits	899	Shared Neighborhood Hits	301
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASB9_MOUSE
NC score	0.427709 (rank : 353)	θ value	1.99992e-07 (rank : 367)
Query Neighborhood Hits	905	Target Neighborhood Hits	257	Shared Neighborhood Hits	247
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

CD2A1_MOUSE
NC score	0.427312 (rank : 354)	θ value	5.26297e-08 (rank : 344)
Query Neighborhood Hits	905	Target Neighborhood Hits	206	Shared Neighborhood Hits	202
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

ITB2_HUMAN
NC score	0.427308 (rank : 355)	θ value	3.64472e-09 (rank : 323)
Query Neighborhood Hits	905	Target Neighborhood Hits	282	Shared Neighborhood Hits	241
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

PGBM_HUMAN
NC score	0.425831 (rank : 356)	θ value	1.2077e-20 (rank : 105)
Query Neighborhood Hits	905	Target Neighborhood Hits	1113	Shared Neighborhood Hits	403
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ITB1_MOUSE
NC score	0.424882 (rank : 357)	θ value	1.69304e-06 (rank : 410)
Query Neighborhood Hits	905	Target Neighborhood Hits	283	Shared Neighborhood Hits	232
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ZDH13_HUMAN
NC score	0.424461 (rank : 358)	θ value	2.52405e-10 (rank : 271)
Query Neighborhood Hits	905	Target Neighborhood Hits	322	Shared Neighborhood Hits	276
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

LAMA3_HUMAN
NC score	0.423909 (rank : 359)	θ value	0.00020696 (rank : 477)
Query Neighborhood Hits	905	Target Neighborhood Hits	760	Shared Neighborhood Hits	278
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

ANR47_HUMAN
NC score	0.423087 (rank : 360)	θ value	7.34386e-10 (rank : 286)
Query Neighborhood Hits	905	Target Neighborhood Hits	369	Shared Neighborhood Hits	254
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

RFXK_MOUSE
NC score	0.423024 (rank : 361)	θ value	0.0113563 (rank : 583)
Query Neighborhood Hits	905	Target Neighborhood Hits	273	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ZDH17_HUMAN
NC score	0.423003 (rank : 362)	θ value	1.33837e-11 (rank : 234)
Query Neighborhood Hits	905	Target Neighborhood Hits	334	Shared Neighborhood Hits	281
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ITB4_HUMAN
NC score	0.422995 (rank : 363)	θ value	7.34386e-10 (rank : 290)
Query Neighborhood Hits	905	Target Neighborhood Hits	458	Shared Neighborhood Hits	267
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ASB6_MOUSE
NC score	0.421875 (rank : 364)	θ value	0.000121331 (rank : 466)
Query Neighborhood Hits	905	Target Neighborhood Hits	264	Shared Neighborhood Hits	246
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ITB1_HUMAN
NC score	0.421526 (rank : 365)	θ value	8.40245e-06 (rank : 426)
Query Neighborhood Hits	905	Target Neighborhood Hits	298	Shared Neighborhood Hits	244
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

BARD1_MOUSE
NC score	0.421107 (rank : 366)	θ value	1.87187e-05 (rank : 442)
Query Neighborhood Hits	905	Target Neighborhood Hits	411	Shared Neighborhood Hits	279
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

TENR_HUMAN
NC score	0.421038 (rank : 367)	θ value	1.86753e-13 (rank : 193)
Query Neighborhood Hits	905	Target Neighborhood Hits	526	Shared Neighborhood Hits	312
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

KR10B_HUMAN
NC score	0.420637 (rank : 368)	θ value	1.43324e-05 (rank : 439)
Query Neighborhood Hits	905	Target Neighborhood Hits	269	Shared Neighborhood Hits	210
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

ANS4B_HUMAN
NC score	0.420144 (rank : 369)	θ value	3.41135e-07 (rank : 379)
Query Neighborhood Hits	905	Target Neighborhood Hits	289	Shared Neighborhood Hits	257
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ZDH13_MOUSE
NC score	0.419780 (rank : 370)	θ value	7.34386e-10 (rank : 295)
Query Neighborhood Hits	905	Target Neighborhood Hits	329	Shared Neighborhood Hits	279
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ZDH17_MOUSE
NC score	0.419418 (rank : 371)	θ value	3.89403e-11 (rank : 246)
Query Neighborhood Hits	905	Target Neighborhood Hits	328	Shared Neighborhood Hits	276
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

SSPO_MOUSE
NC score	0.419275 (rank : 372)	θ value	1.058e-16 (rank : 152)
Query Neighborhood Hits	905	Target Neighborhood Hits	800	Shared Neighborhood Hits	398
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

FATH_HUMAN
NC score	0.418854 (rank : 373)	θ value	1.9192e-34 (rank : 58)
Query Neighborhood Hits	905	Target Neighborhood Hits	570	Shared Neighborhood Hits	346
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

SHAN1_HUMAN
NC score	0.418388 (rank : 374)	θ value	1.80466e-16 (rank : 155)
Query Neighborhood Hits	905	Target Neighborhood Hits	1041	Shared Neighborhood Hits	298
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TSP2_HUMAN
NC score	0.417784 (rank : 375)	θ value	1.133e-10 (rank : 258)
Query Neighborhood Hits	905	Target Neighborhood Hits	359	Shared Neighborhood Hits	257
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

NFKB1_MOUSE
NC score	0.416405 (rank : 376)	θ value	1.02475e-11 (rank : 230)
Query Neighborhood Hits	905	Target Neighborhood Hits	300	Shared Neighborhood Hits	271
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

NFKB1_HUMAN
NC score	0.416250 (rank : 377)	θ value	7.34386e-10 (rank : 293)
Query Neighborhood Hits	905	Target Neighborhood Hits	306	Shared Neighborhood Hits	276
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ATRN_HUMAN
NC score	0.415032 (rank : 378)	θ value	8.40245e-06 (rank : 424)
Query Neighborhood Hits	905	Target Neighborhood Hits	525	Shared Neighborhood Hits	303
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ASB6_HUMAN
NC score	0.413990 (rank : 379)	θ value	0.00102713 (rank : 506)
Query Neighborhood Hits	905	Target Neighborhood Hits	256	Shared Neighborhood Hits	248
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ATRN_MOUSE
NC score	0.413847 (rank : 380)	θ value	0.00020696 (rank : 475)
Query Neighborhood Hits	905	Target Neighborhood Hits	519	Shared Neighborhood Hits	300
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

NFKB2_HUMAN
NC score	0.413135 (rank : 381)	θ value	5.62301e-10 (rank : 281)
Query Neighborhood Hits	905	Target Neighborhood Hits	325	Shared Neighborhood Hits	282
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

FRAS1_HUMAN
NC score	0.412610 (rank : 382)	θ value	4.91457e-14 (rank : 180)
Query Neighborhood Hits	905	Target Neighborhood Hits	759	Shared Neighborhood Hits	342
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA4_HUMAN
NC score	0.412023 (rank : 383)	θ value	1.38499e-08 (rank : 331)
Query Neighborhood Hits	905	Target Neighborhood Hits	708	Shared Neighborhood Hits	244
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

ANR21_HUMAN
NC score	0.411894 (rank : 384)	θ value	9.59137e-10 (rank : 297)
Query Neighborhood Hits	905	Target Neighborhood Hits	864	Shared Neighborhood Hits	284
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANS4B_MOUSE
NC score	0.411161 (rank : 385)	θ value	8.40245e-06 (rank : 423)
Query Neighborhood Hits	905	Target Neighborhood Hits	294	Shared Neighborhood Hits	253
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

POT15_HUMAN
NC score	0.410893 (rank : 386)	θ value	5.62301e-10 (rank : 282)
Query Neighborhood Hits	905	Target Neighborhood Hits	893	Shared Neighborhood Hits	286
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

CFC1_HUMAN
NC score	0.410758 (rank : 387)	θ value	0.0252991 (rank : 601)
Query Neighborhood Hits	905	Target Neighborhood Hits	148	Shared Neighborhood Hits	146
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

TSP2_MOUSE
NC score	0.410642 (rank : 388)	θ value	1.38499e-08 (rank : 333)
Query Neighborhood Hits	905	Target Neighborhood Hits	352	Shared Neighborhood Hits	249
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ANR38_HUMAN
NC score	0.409563 (rank : 389)	θ value	1.06045e-08 (rank : 329)
Query Neighborhood Hits	905	Target Neighborhood Hits	443	Shared Neighborhood Hits	243
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR37_HUMAN
NC score	0.407375 (rank : 390)	θ value	0.00390308 (rank : 546)
Query Neighborhood Hits	905	Target Neighborhood Hits	247	Shared Neighborhood Hits	245
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ANR25_HUMAN
NC score	0.407199 (rank : 391)	θ value	4.45536e-07 (rank : 384)
Query Neighborhood Hits	905	Target Neighborhood Hits	350	Shared Neighborhood Hits	259
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

KR510_HUMAN
NC score	0.405742 (rank : 392)	θ value	0.00665767 (rank : 563)
Query Neighborhood Hits	905	Target Neighborhood Hits	217	Shared Neighborhood Hits	164
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

ANKY2_HUMAN
NC score	0.405280 (rank : 393)	θ value	0.00035302 (rank : 482)
Query Neighborhood Hits	905	Target Neighborhood Hits	306	Shared Neighborhood Hits	257
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR11_HUMAN
NC score	0.405218 (rank : 394)	θ value	1.25267e-09 (rank : 308)
Query Neighborhood Hits	905	Target Neighborhood Hits	1289	Shared Neighborhood Hits	296
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CTTB2_HUMAN
NC score	0.403841 (rank : 395)	θ value	3.89403e-11 (rank : 242)
Query Neighborhood Hits	905	Target Neighborhood Hits	1061	Shared Neighborhood Hits	295
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR32_HUMAN
NC score	0.403776 (rank : 396)	θ value	0.21417 (rank : 674)
Query Neighborhood Hits	905	Target Neighborhood Hits	270	Shared Neighborhood Hits	259
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR33_MOUSE
NC score	0.400420 (rank : 397)	θ value	0.00134147 (rank : 514)
Query Neighborhood Hits	905	Target Neighborhood Hits	225	Shared Neighborhood Hits	219
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR32_MOUSE
NC score	0.399923 (rank : 398)	θ value	0.0113563 (rank : 578)
Query Neighborhood Hits	905	Target Neighborhood Hits	285	Shared Neighborhood Hits	259
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR38_MOUSE
NC score	0.399471 (rank : 399)	θ value	1.63604e-09 (rank : 313)
Query Neighborhood Hits	905	Target Neighborhood Hits	512	Shared Neighborhood Hits	235
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

NFKB2_MOUSE
NC score	0.399048 (rank : 400)	θ value	1.53129e-07 (rank : 366)
Query Neighborhood Hits	905	Target Neighborhood Hits	326	Shared Neighborhood Hits	276
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

CDN2B_MOUSE
NC score	0.398172 (rank : 401)	θ value	8.40245e-06 (rank : 425)
Query Neighborhood Hits	905	Target Neighborhood Hits	201	Shared Neighborhood Hits	197
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

ANR37_MOUSE
NC score	0.396728 (rank : 402)	θ value	0.000602161 (rank : 495)
Query Neighborhood Hits	905	Target Neighborhood Hits	237	Shared Neighborhood Hits	236
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

FRAS1_MOUSE
NC score	0.395937 (rank : 403)	θ value	2.20605e-14 (rank : 175)
Query Neighborhood Hits	905	Target Neighborhood Hits	747	Shared Neighborhood Hits	327
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ANR25_MOUSE
NC score	0.394979 (rank : 404)	θ value	4.45536e-07 (rank : 385)
Query Neighborhood Hits	905	Target Neighborhood Hits	398	Shared Neighborhood Hits	257
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR12_HUMAN
NC score	0.394353 (rank : 405)	θ value	4.59992e-12 (rank : 216)
Query Neighborhood Hits	905	Target Neighborhood Hits	1081	Shared Neighborhood Hits	286
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CLPB_MOUSE
NC score	0.393883 (rank : 406)	θ value	0.000461057 (rank : 490)
Query Neighborhood Hits	905	Target Neighborhood Hits	289	Shared Neighborhood Hits	255
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANKY2_MOUSE
NC score	0.392243 (rank : 407)	θ value	0.00020696 (rank : 474)
Query Neighborhood Hits	905	Target Neighborhood Hits	316	Shared Neighborhood Hits	255
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

POT14_HUMAN
NC score	0.391330 (rank : 408)	θ value	3.19293e-05 (rank : 453)
Query Neighborhood Hits	905	Target Neighborhood Hits	403	Shared Neighborhood Hits	266
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

CFC1_MOUSE
NC score	0.389925 (rank : 409)	θ value	0.00228821 (rank : 530)
Query Neighborhood Hits	905	Target Neighborhood Hits	125	Shared Neighborhood Hits	124
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CDN2B_HUMAN
NC score	0.387655 (rank : 410)	θ value	2.61198e-07 (rank : 374)
Query Neighborhood Hits	905	Target Neighborhood Hits	196	Shared Neighborhood Hits	193
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

ANR33_HUMAN
NC score	0.383880 (rank : 411)	θ value	0.0148317 (rank : 587)
Query Neighborhood Hits	905	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CELR2_HUMAN
NC score	0.381470 (rank : 412)	θ value	1.058e-16 (rank : 151)
Query Neighborhood Hits	905	Target Neighborhood Hits	657	Shared Neighborhood Hits	367
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

A20A3_HUMAN
NC score	0.380737 (rank : 413)	θ value	1.25267e-09 (rank : 305)
Query Neighborhood Hits	905	Target Neighborhood Hits	692	Shared Neighborhood Hits	280
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

CELR3_HUMAN
NC score	0.380515 (rank : 414)	θ value	2.87452e-22 (rank : 88)
Query Neighborhood Hits	905	Target Neighborhood Hits	680	Shared Neighborhood Hits	344
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

BCOR_MOUSE
NC score	0.379965 (rank : 415)	θ value	3.19293e-05 (rank : 449)
Query Neighborhood Hits	905	Target Neighborhood Hits	521	Shared Neighborhood Hits	269
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

A20A1_HUMAN
NC score	0.379444 (rank : 416)	θ value	1.25267e-09 (rank : 303)
Query Neighborhood Hits	905	Target Neighborhood Hits	698	Shared Neighborhood Hits	276
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

KRA13_HUMAN
NC score	0.379423 (rank : 417)	θ value	0.000602161 (rank : 497)
Query Neighborhood Hits	905	Target Neighborhood Hits	144	Shared Neighborhood Hits	122
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

TDGF1_MOUSE
NC score	0.378970 (rank : 418)	θ value	0.0330416 (rank : 617)
Query Neighborhood Hits	905	Target Neighborhood Hits	146	Shared Neighborhood Hits	144
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

A20A2_HUMAN
NC score	0.378894 (rank : 419)	θ value	1.25267e-09 (rank : 304)
Query Neighborhood Hits	905	Target Neighborhood Hits	716	Shared Neighborhood Hits	279
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A4_HUMAN
NC score	0.378140 (rank : 420)	θ value	1.25267e-09 (rank : 306)
Query Neighborhood Hits	905	Target Neighborhood Hits	710	Shared Neighborhood Hits	280
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ELTD1_HUMAN
NC score	0.378101 (rank : 421)	θ value	8.97725e-08 (rank : 357)
Query Neighborhood Hits	905	Target Neighborhood Hits	269	Shared Neighborhood Hits	189
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

CELR3_MOUSE
NC score	0.375825 (rank : 422)	θ value	6.40375e-22 (rank : 92)
Query Neighborhood Hits	905	Target Neighborhood Hits	687	Shared Neighborhood Hits	352
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

OSBL1_HUMAN
NC score	0.375414 (rank : 423)	θ value	4.30538e-10 (rank : 277)
Query Neighborhood Hits	905	Target Neighborhood Hits	368	Shared Neighborhood Hits	281
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

BCOR_HUMAN
NC score	0.374189 (rank : 424)	θ value	2.44474e-05 (rank : 446)
Query Neighborhood Hits	905	Target Neighborhood Hits	609	Shared Neighborhood Hits	270
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

POT22_HUMAN
NC score	0.372295 (rank : 425)	θ value	0.00665767 (rank : 571)
Query Neighborhood Hits	905	Target Neighborhood Hits	266	Shared Neighborhood Hits	257
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

MPP8_HUMAN
NC score	0.371814 (rank : 426)	θ value	3.41135e-07 (rank : 380)
Query Neighborhood Hits	905	Target Neighborhood Hits	948	Shared Neighborhood Hits	258
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

SORL_MOUSE
NC score	0.371620 (rank : 427)	θ value	6.87365e-08 (rank : 354)
Query Neighborhood Hits	905	Target Neighborhood Hits	439	Shared Neighborhood Hits	254
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LYAM3_MOUSE
NC score	0.370804 (rank : 428)	θ value	2.21117e-06 (rank : 414)
Query Neighborhood Hits	905	Target Neighborhood Hits	390	Shared Neighborhood Hits	261
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CD2A1_HUMAN
NC score	0.368994 (rank : 429)	θ value	3.19293e-05 (rank : 451)
Query Neighborhood Hits	905	Target Neighborhood Hits	196	Shared Neighborhood Hits	192
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

KRIT1_MOUSE
NC score	0.368110 (rank : 430)	θ value	0.0330416 (rank : 614)
Query Neighborhood Hits	905	Target Neighborhood Hits	258	Shared Neighborhood Hits	226
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

KRIT1_HUMAN
NC score	0.367795 (rank : 431)	θ value	0.00665767 (rank : 564)
Query Neighborhood Hits	905	Target Neighborhood Hits	258	Shared Neighborhood Hits	219
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRA94_HUMAN
NC score	0.367475 (rank : 432)	θ value	0.125558 (rank : 662)
Query Neighborhood Hits	905	Target Neighborhood Hits	204	Shared Neighborhood Hits	170
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

RAI14_HUMAN
NC score	0.366913 (rank : 433)	θ value	1.09485e-13 (rank : 187)
Query Neighborhood Hits	905	Target Neighborhood Hits	1367	Shared Neighborhood Hits	316
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

OSBL1_MOUSE
NC score	0.366863 (rank : 434)	θ value	7.34386e-10 (rank : 294)
Query Neighborhood Hits	905	Target Neighborhood Hits	336	Shared Neighborhood Hits	281
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ITB8_HUMAN
NC score	0.366736 (rank : 435)	θ value	0.000602161 (rank : 496)
Query Neighborhood Hits	905	Target Neighborhood Hits	280	Shared Neighborhood Hits	234
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KRA93_HUMAN
NC score	0.365850 (rank : 436)	θ value	0.0330416 (rank : 613)
Query Neighborhood Hits	905	Target Neighborhood Hits	203	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

CELR1_MOUSE
NC score	0.365779 (rank : 437)	θ value	9.56915e-18 (rank : 131)
Query Neighborhood Hits	905	Target Neighborhood Hits	617	Shared Neighborhood Hits	326
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR1_HUMAN
NC score	0.364439 (rank : 438)	θ value	1.24977e-17 (rank : 134)
Query Neighborhood Hits	905	Target Neighborhood Hits	613	Shared Neighborhood Hits	324
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

KRA44_HUMAN
NC score	0.364427 (rank : 439)	θ value	0.000461057 (rank : 493)
Query Neighborhood Hits	905	Target Neighborhood Hits	162	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

TENN_MOUSE
NC score	0.363270 (rank : 440)	θ value	5.62301e-10 (rank : 284)
Query Neighborhood Hits	905	Target Neighborhood Hits	484	Shared Neighborhood Hits	282
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

KRA98_HUMAN
NC score	0.361654 (rank : 441)	θ value	0.365318 (rank : 713)
Query Neighborhood Hits	905	Target Neighborhood Hits	185	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA45_HUMAN
NC score	0.360867 (rank : 442)	θ value	0.00102713 (rank : 510)
Query Neighborhood Hits	905	Target Neighborhood Hits	194	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

SORL_HUMAN
NC score	0.358880 (rank : 443)	θ value	5.81887e-07 (rank : 396)
Query Neighborhood Hits	905	Target Neighborhood Hits	440	Shared Neighborhood Hits	245
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

HECD1_HUMAN
NC score	0.358402 (rank : 444)	θ value	5.26297e-08 (rank : 346)
Query Neighborhood Hits	905	Target Neighborhood Hits	371	Shared Neighborhood Hits	273
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

KR10A_HUMAN
NC score	0.357500 (rank : 445)	θ value	1.87187e-05 (rank : 443)
Query Neighborhood Hits	905	Target Neighborhood Hits	232	Shared Neighborhood Hits	187
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

ANR18_HUMAN
NC score	0.356104 (rank : 446)	θ value	6.64225e-11 (rank : 251)
Query Neighborhood Hits	905	Target Neighborhood Hits	1106	Shared Neighborhood Hits	288
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

KR414_HUMAN
NC score	0.353241 (rank : 447)	θ value	7.1131e-05 (rank : 460)
Query Neighborhood Hits	905	Target Neighborhood Hits	199	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

NET4_HUMAN
NC score	0.352433 (rank : 448)	θ value	0.00035302 (rank : 485)
Query Neighborhood Hits	905	Target Neighborhood Hits	191	Shared Neighborhood Hits	162
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

KRA11_HUMAN
NC score	0.352377 (rank : 449)	θ value	0.00035302 (rank : 483)
Query Neighborhood Hits	905	Target Neighborhood Hits	155	Shared Neighborhood Hits	134
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

HABP2_HUMAN
NC score	0.351317 (rank : 450)	θ value	9.56915e-18 (rank : 132)
Query Neighborhood Hits	905	Target Neighborhood Hits	431	Shared Neighborhood Hits	271
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
NC score	0.350637 (rank : 451)	θ value	1.02238e-19 (rank : 114)
Query Neighborhood Hits	905	Target Neighborhood Hits	445	Shared Neighborhood Hits	282
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

SNCAP_HUMAN
NC score	0.350554 (rank : 452)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	905	Target Neighborhood Hits	313	Shared Neighborhood Hits	236
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

KRA47_HUMAN
NC score	0.349685 (rank : 453)	θ value	0.0193708 (rank : 596)
Query Neighborhood Hits	905	Target Neighborhood Hits	204	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

ANR40_HUMAN
NC score	0.348700 (rank : 454)	θ value	0.00665767 (rank : 560)
Query Neighborhood Hits	905	Target Neighborhood Hits	224	Shared Neighborhood Hits	201
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ZAN_HUMAN
NC score	0.348416 (rank : 455)	θ value	0.00102713 (rank : 512)
Query Neighborhood Hits	905	Target Neighborhood Hits	679	Shared Neighborhood Hits	315
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

KR103_HUMAN
NC score	0.347785 (rank : 456)	θ value	0.00020696 (rank : 476)
Query Neighborhood Hits	905	Target Neighborhood Hits	212	Shared Neighborhood Hits	171
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

LYAM2_HUMAN
NC score	0.347705 (rank : 457)	θ value	4.45536e-07 (rank : 390)
Query Neighborhood Hits	905	Target Neighborhood Hits	394	Shared Neighborhood Hits	258
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

NET2_MOUSE
NC score	0.347675 (rank : 458)	θ value	0.00665767 (rank : 567)
Query Neighborhood Hits	905	Target Neighborhood Hits	193	Shared Neighborhood Hits	161
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

CELR2_MOUSE
NC score	0.347501 (rank : 459)	θ value	2.20605e-14 (rank : 174)
Query Neighborhood Hits	905	Target Neighborhood Hits	584	Shared Neighborhood Hits	316
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

NET4_MOUSE
NC score	0.346497 (rank : 460)	θ value	0.00298849 (rank : 544)
Query Neighborhood Hits	905	Target Neighborhood Hits	180	Shared Neighborhood Hits	159
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

LYAM2_MOUSE
NC score	0.346133 (rank : 461)	θ value	1.43324e-05 (rank : 440)
Query Neighborhood Hits	905	Target Neighborhood Hits	420	Shared Neighborhood Hits	280
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

TENN_HUMAN
NC score	0.345875 (rank : 462)	θ value	3.89403e-11 (rank : 245)
Query Neighborhood Hits	905	Target Neighborhood Hits	453	Shared Neighborhood Hits	277
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

NET2_HUMAN
NC score	0.345082 (rank : 463)	θ value	0.00228821 (rank : 536)
Query Neighborhood Hits	905	Target Neighborhood Hits	194	Shared Neighborhood Hits	154
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

ANR43_HUMAN
NC score	0.343367 (rank : 464)	θ value	0.00298849 (rank : 539)
Query Neighborhood Hits	905	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

NFX1_HUMAN
NC score	0.343034 (rank : 465)	θ value	1.09739e-05 (rank : 435)
Query Neighborhood Hits	905	Target Neighborhood Hits	405	Shared Neighborhood Hits	183
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

ANR40_MOUSE
NC score	0.342914 (rank : 466)	θ value	0.00509761 (rank : 554)
Query Neighborhood Hits	905	Target Neighborhood Hits	228	Shared Neighborhood Hits	204
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

RAI14_MOUSE
NC score	0.341591 (rank : 467)	θ value	3.52202e-12 (rank : 215)
Query Neighborhood Hits	905	Target Neighborhood Hits	1505	Shared Neighborhood Hits	318
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

KRA92_HUMAN
NC score	0.341448 (rank : 468)	θ value	0.21417 (rank : 681)
Query Neighborhood Hits	905	Target Neighborhood Hits	198	Shared Neighborhood Hits	157
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

OSTF1_MOUSE
NC score	0.337868 (rank : 469)	θ value	0.000158464 (rank : 472)
Query Neighborhood Hits	905	Target Neighborhood Hits	467	Shared Neighborhood Hits	252
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

LCE1B_HUMAN
NC score	0.336967 (rank : 470)	θ value	0.0961366 (rank : 650)
Query Neighborhood Hits	905	Target Neighborhood Hits	58	Shared Neighborhood Hits	43
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

CLPB_HUMAN
NC score	0.334897 (rank : 471)	θ value	0.0736092 (rank : 638)
Query Neighborhood Hits	905	Target Neighborhood Hits	265	Shared Neighborhood Hits	236
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR43_MOUSE
NC score	0.333588 (rank : 472)	θ value	0.00175202 (rank : 521)
Query Neighborhood Hits	905	Target Neighborhood Hits	214	Shared Neighborhood Hits	204
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

KR412_HUMAN
NC score	0.333360 (rank : 473)	θ value	0.00298849 (rank : 541)
Query Neighborhood Hits	905	Target Neighborhood Hits	178	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

LYAM3_HUMAN
NC score	0.330256 (rank : 474)	θ value	1.87187e-05 (rank : 444)
Query Neighborhood Hits	905	Target Neighborhood Hits	378	Shared Neighborhood Hits	238
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

OSTF1_HUMAN
NC score	0.329885 (rank : 475)	θ value	0.00035302 (rank : 486)
Query Neighborhood Hits	905	Target Neighborhood Hits	466	Shared Neighborhood Hits	250
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

TRPV6_MOUSE
NC score	0.329687 (rank : 476)	θ value	3.77169e-06 (rank : 418)
Query Neighborhood Hits	905	Target Neighborhood Hits	284	Shared Neighborhood Hits	250
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TDGF1_HUMAN
NC score	0.328115 (rank : 477)	θ value	0.0193708 (rank : 598)
Query Neighborhood Hits	905	Target Neighborhood Hits	132	Shared Neighborhood Hits	130
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

AN30A_HUMAN
NC score	0.327486 (rank : 478)	θ value	2.61198e-07 (rank : 372)
Query Neighborhood Hits	905	Target Neighborhood Hits	1119	Shared Neighborhood Hits	275
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

KRA15_HUMAN
NC score	0.327347 (rank : 479)	θ value	0.00175202 (rank : 527)
Query Neighborhood Hits	905	Target Neighborhood Hits	126	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

LCE1C_HUMAN
NC score	0.327226 (rank : 480)	θ value	0.0330416 (rank : 615)
Query Neighborhood Hits	905	Target Neighborhood Hits	65	Shared Neighborhood Hits	46
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

KRA99_HUMAN
NC score	0.322728 (rank : 481)	θ value	0.0148317 (rank : 591)
Query Neighborhood Hits	905	Target Neighborhood Hits	173	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

TDGF2_HUMAN
NC score	0.322422 (rank : 482)	θ value	0.0431538 (rank : 627)
Query Neighborhood Hits	905	Target Neighborhood Hits	131	Shared Neighborhood Hits	126
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

ANKK1_HUMAN
NC score	0.317128 (rank : 483)	θ value	6.40375e-22 (rank : 91)
Query Neighborhood Hits	905	Target Neighborhood Hits	1075	Shared Neighborhood Hits	313
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

MUC5B_HUMAN
NC score	0.316753 (rank : 484)	θ value	5.26297e-08 (rank : 351)
Query Neighborhood Hits	905	Target Neighborhood Hits	1020	Shared Neighborhood Hits	322
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

VWF_HUMAN
NC score	0.313617 (rank : 485)	θ value	9.92553e-07 (rank : 404)
Query Neighborhood Hits	905	Target Neighborhood Hits	396	Shared Neighborhood Hits	253
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ANKK1_MOUSE
NC score	0.308111 (rank : 486)	θ value	1.5773e-20 (rank : 107)
Query Neighborhood Hits	905	Target Neighborhood Hits	1072	Shared Neighborhood Hits	313
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

CENB1_HUMAN
NC score	0.306439 (rank : 487)	θ value	5.44631e-05 (rank : 457)
Query Neighborhood Hits	905	Target Neighborhood Hits	383	Shared Neighborhood Hits	254
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

IASPP_HUMAN
NC score	0.305572 (rank : 488)	θ value	0.00175202 (rank : 526)
Query Neighborhood Hits	905	Target Neighborhood Hits	688	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ABTB2_HUMAN
NC score	0.305551 (rank : 489)	θ value	0.00509761 (rank : 552)
Query Neighborhood Hits	905	Target Neighborhood Hits	391	Shared Neighborhood Hits	236
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

RIPK4_HUMAN
NC score	0.305463 (rank : 490)	θ value	5.8054e-15 (rank : 172)
Query Neighborhood Hits	905	Target Neighborhood Hits	1094	Shared Neighborhood Hits	317
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

TEFF2_MOUSE
NC score	0.305245 (rank : 491)	θ value	0.0252991 (rank : 608)
Query Neighborhood Hits	905	Target Neighborhood Hits	214	Shared Neighborhood Hits	155
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

ASB14_HUMAN
NC score	0.304497 (rank : 492)	θ value	3.0926 (rank : 796)
Query Neighborhood Hits	905	Target Neighborhood Hits	187	Shared Neighborhood Hits	172
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

TEFF2_HUMAN
NC score	0.304325 (rank : 493)	θ value	0.00869519 (rank : 575)
Query Neighborhood Hits	905	Target Neighborhood Hits	211	Shared Neighborhood Hits	153
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

CENB5_HUMAN
NC score	0.303315 (rank : 494)	θ value	0.00102713 (rank : 507)
Query Neighborhood Hits	905	Target Neighborhood Hits	395	Shared Neighborhood Hits	259
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

NET1_HUMAN
NC score	0.301278 (rank : 495)	θ value	0.163984 (rank : 670)
Query Neighborhood Hits	905	Target Neighborhood Hits	149	Shared Neighborhood Hits	121
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

TRPV5_MOUSE
NC score	0.301198 (rank : 496)	θ value	0.00035302 (rank : 489)
Query Neighborhood Hits	905	Target Neighborhood Hits	278	Shared Neighborhood Hits	244
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

FA10_MOUSE
NC score	0.300985 (rank : 497)	θ value	5.26297e-08 (rank : 345)
Query Neighborhood Hits	905	Target Neighborhood Hits	435	Shared Neighborhood Hits	275
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

ABTB2_MOUSE
NC score	0.297895 (rank : 498)	θ value	0.0113563 (rank : 576)
Query Neighborhood Hits	905	Target Neighborhood Hits	414	Shared Neighborhood Hits	238
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

NET1_MOUSE
NC score	0.296803 (rank : 499)	θ value	0.47712 (rank : 727)
Query Neighborhood Hits	905	Target Neighborhood Hits	151	Shared Neighborhood Hits	120
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

EMR3_HUMAN
NC score	0.296346 (rank : 500)	θ value	0.00665767 (rank : 562)
Query Neighborhood Hits	905	Target Neighborhood Hits	245	Shared Neighborhood Hits	162
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

LCE1D_HUMAN
NC score	0.296337 (rank : 501)	θ value	0.279714 (rank : 697)
Query Neighborhood Hits	905	Target Neighborhood Hits	44	Shared Neighborhood Hits	31
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

TRPV5_HUMAN
NC score	0.295960 (rank : 502)	θ value	8.40245e-06 (rank : 430)
Query Neighborhood Hits	905	Target Neighborhood Hits	261	Shared Neighborhood Hits	221
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

FA10_HUMAN
NC score	0.295928 (rank : 503)	θ value	6.87365e-08 (rank : 353)
Query Neighborhood Hits	905	Target Neighborhood Hits	431	Shared Neighborhood Hits	268
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

CENB2_HUMAN
NC score	0.294648 (rank : 504)	θ value	1.43324e-05 (rank : 437)
Query Neighborhood Hits	905	Target Neighborhood Hits	425	Shared Neighborhood Hits	252
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

PERT_HUMAN
NC score	0.294338 (rank : 505)	θ value	0.00020696 (rank : 479)
Query Neighborhood Hits	905	Target Neighborhood Hits	221	Shared Neighborhood Hits	168
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

UACA_HUMAN
NC score	0.293468 (rank : 506)	θ value	1.33837e-11 (rank : 233)
Query Neighborhood Hits	905	Target Neighborhood Hits	1622	Shared Neighborhood Hits	312
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ASPP2_HUMAN
NC score	0.291282 (rank : 507)	θ value	0.000786445 (rank : 500)
Query Neighborhood Hits	905	Target Neighborhood Hits	1156	Shared Neighborhood Hits	281
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ILK2_HUMAN
NC score	0.291026 (rank : 508)	θ value	5.26297e-08 (rank : 348)
Query Neighborhood Hits	905	Target Neighborhood Hits	848	Shared Neighborhood Hits	300
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ANR45_MOUSE
NC score	0.290118 (rank : 509)	θ value	6.88961 (rank : 856)
Query Neighborhood Hits	905	Target Neighborhood Hits	204	Shared Neighborhood Hits	188
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

GIT2_MOUSE
NC score	0.289600 (rank : 510)	θ value	0.00390308 (rank : 549)
Query Neighborhood Hits	905	Target Neighborhood Hits	323	Shared Neighborhood Hits	250
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

TRPV6_HUMAN
NC score	0.289366 (rank : 511)	θ value	1.87187e-05 (rank : 445)
Query Neighborhood Hits	905	Target Neighborhood Hits	262	Shared Neighborhood Hits	222
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

GIT1_MOUSE
NC score	0.287133 (rank : 512)	θ value	0.000461057 (rank : 492)
Query Neighborhood Hits	905	Target Neighborhood Hits	341	Shared Neighborhood Hits	245
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

FA9_HUMAN
NC score	0.286907 (rank : 513)	θ value	1.29631e-06 (rank : 405)
Query Neighborhood Hits	905	Target Neighborhood Hits	421	Shared Neighborhood Hits	264
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

LYAM1_MOUSE
NC score	0.286884 (rank : 514)	θ value	0.0252991 (rank : 604)
Query Neighborhood Hits	905	Target Neighborhood Hits	332	Shared Neighborhood Hits	210
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LCE1E_HUMAN
NC score	0.286884 (rank : 515)	θ value	0.21417 (rank : 682)
Query Neighborhood Hits	905	Target Neighborhood Hits	53	Shared Neighborhood Hits	35
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

UROL1_MOUSE
NC score	0.286533 (rank : 516)	θ value	0.00298849 (rank : 545)
Query Neighborhood Hits	905	Target Neighborhood Hits	235	Shared Neighborhood Hits	152
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

GIT1_HUMAN
NC score	0.285529 (rank : 517)	θ value	0.000461057 (rank : 491)
Query Neighborhood Hits	905	Target Neighborhood Hits	336	Shared Neighborhood Hits	245
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

PROC_MOUSE
NC score	0.285338 (rank : 518)	θ value	1.69304e-06 (rank : 411)
Query Neighborhood Hits	905	Target Neighborhood Hits	426	Shared Neighborhood Hits	267
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

ASPP1_HUMAN
NC score	0.285259 (rank : 519)	θ value	0.00665767 (rank : 561)
Query Neighborhood Hits	905	Target Neighborhood Hits	956	Shared Neighborhood Hits	270
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

AN13B_MOUSE
NC score	0.285115 (rank : 520)	θ value	0.000602161 (rank : 494)
Query Neighborhood Hits	905	Target Neighborhood Hits	276	Shared Neighborhood Hits	249
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

VWF_MOUSE
NC score	0.284495 (rank : 521)	θ value	9.59137e-10 (rank : 302)
Query Neighborhood Hits	905	Target Neighborhood Hits	381	Shared Neighborhood Hits	235
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

PGCB_MOUSE
NC score	0.284456 (rank : 522)	θ value	9.92553e-07 (rank : 403)
Query Neighborhood Hits	905	Target Neighborhood Hits	459	Shared Neighborhood Hits	200
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

AN13B_HUMAN
NC score	0.283270 (rank : 523)	θ value	0.00102713 (rank : 505)
Query Neighborhood Hits	905	Target Neighborhood Hits	265	Shared Neighborhood Hits	249
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

MUC13_MOUSE
NC score	0.281744 (rank : 524)	θ value	0.0563607 (rank : 631)
Query Neighborhood Hits	905	Target Neighborhood Hits	447	Shared Neighborhood Hits	175
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

UACA_MOUSE
NC score	0.281703 (rank : 525)	θ value	2.0648e-12 (rank : 212)
Query Neighborhood Hits	905	Target Neighborhood Hits	1620	Shared Neighborhood Hits	308
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ILK1_HUMAN
NC score	0.281063 (rank : 526)	θ value	5.26297e-08 (rank : 347)
Query Neighborhood Hits	905	Target Neighborhood Hits	857	Shared Neighborhood Hits	300
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

CRAC1_MOUSE
NC score	0.280526 (rank : 527)	θ value	0.62314 (rank : 734)
Query Neighborhood Hits	905	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

LYAM1_HUMAN
NC score	0.280051 (rank : 528)	θ value	0.0431538 (rank : 625)
Query Neighborhood Hits	905	Target Neighborhood Hits	315	Shared Neighborhood Hits	205
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

ILK_MOUSE
NC score	0.279692 (rank : 529)	θ value	1.17247e-07 (rank : 358)
Query Neighborhood Hits	905	Target Neighborhood Hits	858	Shared Neighborhood Hits	300
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

CRAC1_HUMAN
NC score	0.279518 (rank : 530)	θ value	0.62314 (rank : 733)
Query Neighborhood Hits	905	Target Neighborhood Hits	111	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

ASPP1_MOUSE
NC score	0.277512 (rank : 531)	θ value	0.000786445 (rank : 499)
Query Neighborhood Hits	905	Target Neighborhood Hits	1244	Shared Neighborhood Hits	282
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

NUD12_MOUSE
NC score	0.277234 (rank : 532)	θ value	4.03905 (rank : 821)
Query Neighborhood Hits	905	Target Neighborhood Hits	243	Shared Neighborhood Hits	220
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ANR45_HUMAN
NC score	0.275383 (rank : 533)	θ value	1.06291 (rank : 754)
Query Neighborhood Hits	905	Target Neighborhood Hits	201	Shared Neighborhood Hits	183
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

PERT_MOUSE
NC score	0.275038 (rank : 534)	θ value	0.00035302 (rank : 487)
Query Neighborhood Hits	905	Target Neighborhood Hits	221	Shared Neighborhood Hits	162
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

NRX1A_HUMAN
NC score	0.274964 (rank : 535)	θ value	0.00665767 (rank : 569)
Query Neighborhood Hits	905	Target Neighborhood Hits	170	Shared Neighborhood Hits	138
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
NC score	0.274090 (rank : 536)	θ value	0.00665767 (rank : 570)
Query Neighborhood Hits	905	Target Neighborhood Hits	164	Shared Neighborhood Hits	137
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

ANKY1_HUMAN
NC score	0.273588 (rank : 537)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	905	Target Neighborhood Hits	248	Shared Neighborhood Hits	204
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

FA7_HUMAN
NC score	0.273580 (rank : 538)	θ value	9.59137e-10 (rank : 299)
Query Neighborhood Hits	905	Target Neighborhood Hits	404	Shared Neighborhood Hits	246
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

HGFA_HUMAN
NC score	0.272160 (rank : 539)	θ value	1.86753e-13 (rank : 192)
Query Neighborhood Hits	905	Target Neighborhood Hits	436	Shared Neighborhood Hits	243
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

IASPP_MOUSE
NC score	0.271555 (rank : 540)	θ value	0.00228821 (rank : 533)
Query Neighborhood Hits	905	Target Neighborhood Hits	1024	Shared Neighborhood Hits	280
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ANR26_MOUSE
NC score	0.271491 (rank : 541)	θ value	3.18553e-13 (rank : 197)
Query Neighborhood Hits	905	Target Neighborhood Hits	1554	Shared Neighborhood Hits	312
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

FAT2_HUMAN
NC score	0.271245 (rank : 542)	θ value	4.44505e-15 (rank : 170)
Query Neighborhood Hits	905	Target Neighborhood Hits	507	Shared Neighborhood Hits	243
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

HGFA_MOUSE
NC score	0.268651 (rank : 543)	θ value	2.43908e-13 (rank : 196)
Query Neighborhood Hits	905	Target Neighborhood Hits	419	Shared Neighborhood Hits	247
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

UROL1_HUMAN
NC score	0.267882 (rank : 544)	θ value	0.000602161 (rank : 498)
Query Neighborhood Hits	905	Target Neighborhood Hits	213	Shared Neighborhood Hits	140
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

PGCB_HUMAN
NC score	0.265446 (rank : 545)	θ value	3.19293e-05 (rank : 452)
Query Neighborhood Hits	905	Target Neighborhood Hits	478	Shared Neighborhood Hits	192
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

AN13C_HUMAN
NC score	0.263180 (rank : 546)	θ value	0.0961366 (rank : 648)
Query Neighborhood Hits	905	Target Neighborhood Hits	241	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

KR410_HUMAN
NC score	0.261399 (rank : 547)	θ value	0.365318 (rank : 711)
Query Neighborhood Hits	905	Target Neighborhood Hits	156	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

NRX3A_HUMAN
NC score	0.260325 (rank : 548)	θ value	0.00869519 (rank : 574)
Query Neighborhood Hits	905	Target Neighborhood Hits	164	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

GIT2_HUMAN
NC score	0.258146 (rank : 549)	θ value	0.00509761 (rank : 556)
Query Neighborhood Hits	905	Target Neighborhood Hits	381	Shared Neighborhood Hits	242
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

GLSL_HUMAN
NC score	0.257148 (rank : 550)	θ value	0.0193708 (rank : 595)
Query Neighborhood Hits	905	Target Neighborhood Hits	211	Shared Neighborhood Hits	200
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

PROC_HUMAN
NC score	0.257024 (rank : 551)	θ value	8.40245e-06 (rank : 429)
Query Neighborhood Hits	905	Target Neighborhood Hits	406	Shared Neighborhood Hits	252
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

AN13C_MOUSE
NC score	0.256584 (rank : 552)	θ value	0.47712 (rank : 720)
Query Neighborhood Hits	905	Target Neighborhood Hits	242	Shared Neighborhood Hits	232
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

CNTP2_MOUSE
NC score	0.256449 (rank : 553)	θ value	0.00175202 (rank : 523)
Query Neighborhood Hits	905	Target Neighborhood Hits	194	Shared Neighborhood Hits	145
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

KRA42_HUMAN
NC score	0.255389 (rank : 554)	θ value	0.0252991 (rank : 602)
Query Neighborhood Hits	905	Target Neighborhood Hits	149	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

NUD12_HUMAN
NC score	0.255195 (rank : 555)	θ value	8.99809 (rank : 901)
Query Neighborhood Hits	905	Target Neighborhood Hits	222	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

LCE1F_HUMAN
NC score	0.254015 (rank : 556)	θ value	1.81305 (rank : 780)
Query Neighborhood Hits	905	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

DDFL1_MOUSE
NC score	0.253598 (rank : 557)	θ value	0.279714 (rank : 694)
Query Neighborhood Hits	905	Target Neighborhood Hits	324	Shared Neighborhood Hits	249
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

CNTP2_HUMAN
NC score	0.253575 (rank : 558)	θ value	0.00175202 (rank : 522)
Query Neighborhood Hits	905	Target Neighborhood Hits	199	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

NRX2A_HUMAN
NC score	0.252718 (rank : 559)	θ value	0.0113563 (rank : 581)
Query Neighborhood Hits	905	Target Neighborhood Hits	614	Shared Neighborhood Hits	174
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

GLSL_MOUSE
NC score	0.252505 (rank : 560)	θ value	0.0148317 (rank : 590)
Query Neighborhood Hits	905	Target Neighborhood Hits	212	Shared Neighborhood Hits	200
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ANR26_HUMAN
NC score	0.252318 (rank : 561)	θ value	3.41135e-07 (rank : 378)
Query Neighborhood Hits	905	Target Neighborhood Hits	1614	Shared Neighborhood Hits	308
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CLC14_MOUSE
NC score	0.251383 (rank : 562)	θ value	0.21417 (rank : 676)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	110
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

MMRN1_HUMAN
NC score	0.250793 (rank : 563)	θ value	0.00035302 (rank : 484)
Query Neighborhood Hits	905	Target Neighborhood Hits	636	Shared Neighborhood Hits	180
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

FA12_HUMAN
NC score	0.249480 (rank : 564)	θ value	3.89403e-11 (rank : 244)
Query Neighborhood Hits	905	Target Neighborhood Hits	425	Shared Neighborhood Hits	239
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

LRP6_HUMAN
NC score	0.248375 (rank : 565)	θ value	θ > 10 (rank : 1009)
Query Neighborhood Hits	905	Target Neighborhood Hits	235	Shared Neighborhood Hits	174
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

CNTP4_MOUSE
NC score	0.247354 (rank : 566)	θ value	0.00102713 (rank : 508)
Query Neighborhood Hits	905	Target Neighborhood Hits	193	Shared Neighborhood Hits	149
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

AN13A_HUMAN
NC score	0.245825 (rank : 567)	θ value	0.365318 (rank : 704)
Query Neighborhood Hits	905	Target Neighborhood Hits	243	Shared Neighborhood Hits	216
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

LRP6_MOUSE
NC score	0.244724 (rank : 568)	θ value	θ > 10 (rank : 1010)
Query Neighborhood Hits	905	Target Neighborhood Hits	232	Shared Neighborhood Hits	172
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LCE1A_HUMAN
NC score	0.244465 (rank : 569)	θ value	5.27518 (rank : 842)
Query Neighborhood Hits	905	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

GLSK_HUMAN
NC score	0.244310 (rank : 570)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	905	Target Neighborhood Hits	204	Shared Neighborhood Hits	186
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

CNTP4_HUMAN
NC score	0.240216 (rank : 571)	θ value	0.00134147 (rank : 518)
Query Neighborhood Hits	905	Target Neighborhood Hits	187	Shared Neighborhood Hits	130
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

BMP1_MOUSE
NC score	0.240183 (rank : 572)	θ value	0.0431538 (rank : 621)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	183
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TNI3K_HUMAN
NC score	0.239779 (rank : 573)	θ value	5.08577e-11 (rank : 250)
Query Neighborhood Hits	905	Target Neighborhood Hits	1084	Shared Neighborhood Hits	316
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

LRP5_MOUSE
NC score	0.239462 (rank : 574)	θ value	0.163984 (rank : 668)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	170
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

RELN_MOUSE
NC score	0.238556 (rank : 575)	θ value	0.0113563 (rank : 582)
Query Neighborhood Hits	905	Target Neighborhood Hits	235	Shared Neighborhood Hits	192
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

TLL1_MOUSE
NC score	0.238535 (rank : 576)	θ value	0.0961366 (rank : 653)
Query Neighborhood Hits	905	Target Neighborhood Hits	237	Shared Neighborhood Hits	181
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

BMP1_HUMAN
NC score	0.238408 (rank : 577)	θ value	0.0431538 (rank : 620)
Query Neighborhood Hits	905	Target Neighborhood Hits	233	Shared Neighborhood Hits	182
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CT012_MOUSE
NC score	0.237527 (rank : 578)	θ value	8.99809 (rank : 889)
Query Neighborhood Hits	905	Target Neighborhood Hits	229	Shared Neighborhood Hits	187
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

FA7_MOUSE
NC score	0.237383 (rank : 579)	θ value	4.45536e-07 (rank : 389)
Query Neighborhood Hits	905	Target Neighborhood Hits	374	Shared Neighborhood Hits	220
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

MFGM_HUMAN
NC score	0.237134 (rank : 580)	θ value	0.00665767 (rank : 566)
Query Neighborhood Hits	905	Target Neighborhood Hits	150	Shared Neighborhood Hits	129
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

CLC14_HUMAN
NC score	0.236242 (rank : 581)	θ value	6.88961 (rank : 860)
Query Neighborhood Hits	905	Target Neighborhood Hits	143	Shared Neighborhood Hits	113
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

TNI3K_MOUSE
NC score	0.235937 (rank : 582)	θ value	3.29651e-10 (rank : 275)
Query Neighborhood Hits	905	Target Neighborhood Hits	1079	Shared Neighborhood Hits	315
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

CNTP3_HUMAN
NC score	0.235585 (rank : 583)	θ value	0.00228821 (rank : 531)
Query Neighborhood Hits	905	Target Neighborhood Hits	195	Shared Neighborhood Hits	137
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

TLL2_HUMAN
NC score	0.233080 (rank : 584)	θ value	0.0330416 (rank : 618)
Query Neighborhood Hits	905	Target Neighborhood Hits	241	Shared Neighborhood Hits	182
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

LRP5_HUMAN
NC score	0.231907 (rank : 585)	θ value	0.47712 (rank : 725)
Query Neighborhood Hits	905	Target Neighborhood Hits	224	Shared Neighborhood Hits	166
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

TLL1_HUMAN
NC score	0.231605 (rank : 586)	θ value	0.21417 (rank : 687)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	178
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

AN13A_MOUSE
NC score	0.230633 (rank : 587)	θ value	0.813845 (rank : 741)
Query Neighborhood Hits	905	Target Neighborhood Hits	226	Shared Neighborhood Hits	215
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

RELN_HUMAN
NC score	0.229484 (rank : 588)	θ value	0.00390308 (rank : 550)
Query Neighborhood Hits	905	Target Neighborhood Hits	233	Shared Neighborhood Hits	189
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RECK_HUMAN
NC score	0.225635 (rank : 589)	θ value	0.21417 (rank : 686)
Query Neighborhood Hits	905	Target Neighborhood Hits	189	Shared Neighborhood Hits	129
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

TLL2_MOUSE
NC score	0.225065 (rank : 590)	θ value	0.163984 (rank : 673)
Query Neighborhood Hits	905	Target Neighborhood Hits	240	Shared Neighborhood Hits	181
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

PCSK5_HUMAN
NC score	0.223267 (rank : 591)	θ value	0.21417 (rank : 684)
Query Neighborhood Hits	905	Target Neighborhood Hits	291	Shared Neighborhood Hits	189
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

DAPK1_MOUSE
NC score	0.220609 (rank : 592)	θ value	1.92812e-18 (rank : 122)
Query Neighborhood Hits	905	Target Neighborhood Hits	1138	Shared Neighborhood Hits	312
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

SMDF_HUMAN
NC score	0.219323 (rank : 593)	θ value	0.365318 (rank : 718)
Query Neighborhood Hits	905	Target Neighborhood Hits	117	Shared Neighborhood Hits	83
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

TIE1_HUMAN
NC score	0.218985 (rank : 594)	θ value	1.42992e-13 (rank : 191)
Query Neighborhood Hits	905	Target Neighborhood Hits	1241	Shared Neighborhood Hits	325
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TECTA_MOUSE
NC score	0.218703 (rank : 595)	θ value	0.163984 (rank : 672)
Query Neighborhood Hits	905	Target Neighborhood Hits	244	Shared Neighborhood Hits	200
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

DDEF2_HUMAN
NC score	0.218650 (rank : 596)	θ value	0.00175202 (rank : 524)
Query Neighborhood Hits	905	Target Neighborhood Hits	599	Shared Neighborhood Hits	236
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

EMR4_MOUSE
NC score	0.217531 (rank : 597)	θ value	0.163984 (rank : 666)
Query Neighborhood Hits	905	Target Neighborhood Hits	191	Shared Neighborhood Hits	121
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

DDEF2_MOUSE
NC score	0.217468 (rank : 598)	θ value	0.00175202 (rank : 525)
Query Neighborhood Hits	905	Target Neighborhood Hits	625	Shared Neighborhood Hits	239
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CNTP1_HUMAN
NC score	0.216752 (rank : 599)	θ value	0.0330416 (rank : 611)
Query Neighborhood Hits	905	Target Neighborhood Hits	196	Shared Neighborhood Hits	128
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

DAPK1_HUMAN
NC score	0.215550 (rank : 600)	θ value	6.20254e-17 (rank : 147)
Query Neighborhood Hits	905	Target Neighborhood Hits	1130	Shared Neighborhood Hits	309
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TIE1_MOUSE
NC score	0.215382 (rank : 601)	θ value	8.38298e-14 (rank : 185)
Query Neighborhood Hits	905	Target Neighborhood Hits	1266	Shared Neighborhood Hits	325
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

MEP1A_MOUSE
NC score	0.214911 (rank : 602)	θ value	0.00509761 (rank : 558)
Query Neighborhood Hits	905	Target Neighborhood Hits	166	Shared Neighborhood Hits	135
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

NRG4_HUMAN
NC score	0.213547 (rank : 603)	θ value	0.365318 (rank : 716)
Query Neighborhood Hits	905	Target Neighborhood Hits	85	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

TEX14_HUMAN
NC score	0.213117 (rank : 604)	θ value	0.00175202 (rank : 528)
Query Neighborhood Hits	905	Target Neighborhood Hits	1103	Shared Neighborhood Hits	260
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_MOUSE
NC score	0.212251 (rank : 605)	θ value	0.0252991 (rank : 609)
Query Neighborhood Hits	905	Target Neighborhood Hits	1333	Shared Neighborhood Hits	278
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

PGH2_MOUSE
NC score	0.211953 (rank : 606)	θ value	0.0563607 (rank : 632)
Query Neighborhood Hits	905	Target Neighborhood Hits	113	Shared Neighborhood Hits	104
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

CNTP1_MOUSE
NC score	0.210088 (rank : 607)	θ value	0.0736092 (rank : 639)
Query Neighborhood Hits	905	Target Neighborhood Hits	183	Shared Neighborhood Hits	121
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CT012_HUMAN
NC score	0.210043 (rank : 608)	θ value	6.88961 (rank : 867)
Query Neighborhood Hits	905	Target Neighborhood Hits	205	Shared Neighborhood Hits	179
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

PGCA_HUMAN
NC score	0.209999 (rank : 609)	θ value	0.00035302 (rank : 488)
Query Neighborhood Hits	905	Target Neighborhood Hits	821	Shared Neighborhood Hits	199
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

CENG1_HUMAN
NC score	0.209030 (rank : 610)	θ value	4.1701e-05 (rank : 454)
Query Neighborhood Hits	905	Target Neighborhood Hits	544	Shared Neighborhood Hits	248
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

KR413_HUMAN
NC score	0.208487 (rank : 611)	θ value	1.81305 (rank : 779)
Query Neighborhood Hits	905	Target Neighborhood Hits	112	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

NRG4_MOUSE
NC score	0.207967 (rank : 612)	θ value	0.0961366 (rank : 651)
Query Neighborhood Hits	905	Target Neighborhood Hits	79	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

MEP1A_HUMAN
NC score	0.207714 (rank : 613)	θ value	0.0252991 (rank : 605)
Query Neighborhood Hits	905	Target Neighborhood Hits	162	Shared Neighborhood Hits	136
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

BMPER_MOUSE
NC score	0.206416 (rank : 614)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	905	Target Neighborhood Hits	194	Shared Neighborhood Hits	141
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

NRG1_HUMAN
NC score	0.205816 (rank : 615)	θ value	0.0330416 (rank : 616)
Query Neighborhood Hits	905	Target Neighborhood Hits	285	Shared Neighborhood Hits	105
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

CENG1_MOUSE
NC score	0.205666 (rank : 616)	θ value	0.00134147 (rank : 515)
Query Neighborhood Hits	905	Target Neighborhood Hits	531	Shared Neighborhood Hits	244
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

NRG2_MOUSE
NC score	0.204466 (rank : 617)	θ value	0.00665767 (rank : 568)
Query Neighborhood Hits	905	Target Neighborhood Hits	392	Shared Neighborhood Hits	130
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

LCE3A_HUMAN
NC score	0.204337 (rank : 618)	θ value	0.47712 (rank : 723)
Query Neighborhood Hits	905	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

MUC2_HUMAN
NC score	0.204009 (rank : 619)	θ value	0.00020696 (rank : 478)
Query Neighborhood Hits	905	Target Neighborhood Hits	906	Shared Neighborhood Hits	204
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CORIN_HUMAN
NC score	0.203622 (rank : 620)	θ value	4.45536e-07 (rank : 387)
Query Neighborhood Hits	905	Target Neighborhood Hits	453	Shared Neighborhood Hits	233
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CO7_HUMAN
NC score	0.202132 (rank : 621)	θ value	0.00509761 (rank : 555)
Query Neighborhood Hits	905	Target Neighborhood Hits	278	Shared Neighborhood Hits	149
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

DGKZ_HUMAN
NC score	0.201794 (rank : 622)	θ value	0.0148317 (rank : 588)
Query Neighborhood Hits	905	Target Neighborhood Hits	551	Shared Neighborhood Hits	218
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CO6_HUMAN
NC score	0.201176 (rank : 623)	θ value	0.0330416 (rank : 612)
Query Neighborhood Hits	905	Target Neighborhood Hits	331	Shared Neighborhood Hits	185
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

ADAM8_MOUSE
NC score	0.200612 (rank : 624)	θ value	0.000158464 (rank : 468)
Query Neighborhood Hits	905	Target Neighborhood Hits	326	Shared Neighborhood Hits	211
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

DDFL1_HUMAN
NC score	0.199176 (rank : 625)	θ value	3.0926 (rank : 802)
Query Neighborhood Hits	905	Target Neighborhood Hits	353	Shared Neighborhood Hits	232
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

PGH2_HUMAN
NC score	0.198740 (rank : 626)	θ value	0.0252991 (rank : 606)
Query Neighborhood Hits	905	Target Neighborhood Hits	103	Shared Neighborhood Hits	93
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

ESM1_HUMAN
NC score	0.198608 (rank : 627)	θ value	0.47712 (rank : 721)
Query Neighborhood Hits	905	Target Neighborhood Hits	110	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

IKBL_HUMAN
NC score	0.197399 (rank : 628)	θ value	0.0736092 (rank : 641)
Query Neighborhood Hits	905	Target Neighborhood Hits	168	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

TECTA_HUMAN
NC score	0.196853 (rank : 629)	θ value	1.06291 (rank : 762)
Query Neighborhood Hits	905	Target Neighborhood Hits	239	Shared Neighborhood Hits	191
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

MATN1_HUMAN
NC score	0.196589 (rank : 630)	θ value	6.88961 (rank : 877)
Query Neighborhood Hits	905	Target Neighborhood Hits	191	Shared Neighborhood Hits	141
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
NC score	0.194196 (rank : 631)	θ value	θ > 10 (rank : 1011)
Query Neighborhood Hits	905	Target Neighborhood Hits	186	Shared Neighborhood Hits	137
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

IKBL_MOUSE
NC score	0.194118 (rank : 632)	θ value	0.0736092 (rank : 642)
Query Neighborhood Hits	905	Target Neighborhood Hits	196	Shared Neighborhood Hits	139
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

DGKZ_MOUSE
NC score	0.193401 (rank : 633)	θ value	0.0148317 (rank : 589)
Query Neighborhood Hits	905	Target Neighborhood Hits	542	Shared Neighborhood Hits	203
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG2_MOUSE
NC score	0.193103 (rank : 634)	θ value	0.0193708 (rank : 593)
Query Neighborhood Hits	905	Target Neighborhood Hits	463	Shared Neighborhood Hits	251
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENG2_HUMAN
NC score	0.192465 (rank : 635)	θ value	0.0736092 (rank : 637)
Query Neighborhood Hits	905	Target Neighborhood Hits	471	Shared Neighborhood Hits	253
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

APR3_MOUSE
NC score	0.192398 (rank : 636)	θ value	0.0563607 (rank : 630)
Query Neighborhood Hits	905	Target Neighborhood Hits	61	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ANKZ1_MOUSE
NC score	0.191763 (rank : 637)	θ value	0.0563607 (rank : 629)
Query Neighborhood Hits	905	Target Neighborhood Hits	208	Shared Neighborhood Hits	151
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

DGKI_HUMAN
NC score	0.190617 (rank : 638)	θ value	0.0736092 (rank : 640)
Query Neighborhood Hits	905	Target Neighborhood Hits	609	Shared Neighborhood Hits	219
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

TIE2_HUMAN
NC score	0.190322 (rank : 639)	θ value	3.64472e-09 (rank : 324)
Query Neighborhood Hits	905	Target Neighborhood Hits	1192	Shared Neighborhood Hits	296
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

CENG3_HUMAN
NC score	0.190133 (rank : 640)	θ value	0.00134147 (rank : 516)
Query Neighborhood Hits	905	Target Neighborhood Hits	455	Shared Neighborhood Hits	229
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ADA11_HUMAN
NC score	0.190070 (rank : 641)	θ value	0.00102713 (rank : 504)
Query Neighborhood Hits	905	Target Neighborhood Hits	259	Shared Neighborhood Hits	191
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CENG3_MOUSE
NC score	0.189997 (rank : 642)	θ value	0.00134147 (rank : 517)
Query Neighborhood Hits	905	Target Neighborhood Hits	467	Shared Neighborhood Hits	230
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

PCSK6_HUMAN
NC score	0.189691 (rank : 643)	θ value	0.0736092 (rank : 644)
Query Neighborhood Hits	905	Target Neighborhood Hits	298	Shared Neighborhood Hits	164
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

KRA24_HUMAN
NC score	0.189598 (rank : 644)	θ value	0.0736092 (rank : 643)
Query Neighborhood Hits	905	Target Neighborhood Hits	192	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

TIE2_MOUSE
NC score	0.189463 (rank : 645)	θ value	1.63604e-09 (rank : 315)
Query Neighborhood Hits	905	Target Neighborhood Hits	1204	Shared Neighborhood Hits	301
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

BMPER_HUMAN
NC score	0.189172 (rank : 646)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	905	Target Neighborhood Hits	175	Shared Neighborhood Hits	128
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

ADA11_MOUSE
NC score	0.188778 (rank : 647)	θ value	0.0148317 (rank : 586)
Query Neighborhood Hits	905	Target Neighborhood Hits	263	Shared Neighborhood Hits	192
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ANKZ1_HUMAN
NC score	0.187218 (rank : 648)	θ value	0.0736092 (rank : 634)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	158
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

PGH1_MOUSE
NC score	0.186858 (rank : 649)	θ value	0.21417 (rank : 685)
Query Neighborhood Hits	905	Target Neighborhood Hits	100	Shared Neighborhood Hits	85
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

RECK_MOUSE
NC score	0.186737 (rank : 650)	θ value	3.0926 (rank : 812)
Query Neighborhood Hits	905	Target Neighborhood Hits	158	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

CO8B_MOUSE
NC score	0.185413 (rank : 651)	θ value	0.00390308 (rank : 548)
Query Neighborhood Hits	905	Target Neighborhood Hits	224	Shared Neighborhood Hits	128
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADAM8_HUMAN
NC score	0.185024 (rank : 652)	θ value	0.00175202 (rank : 520)
Query Neighborhood Hits	905	Target Neighborhood Hits	327	Shared Neighborhood Hits	228
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

MUC13_HUMAN
NC score	0.184383 (rank : 653)	θ value	3.0926 (rank : 810)
Query Neighborhood Hits	905	Target Neighborhood Hits	164	Shared Neighborhood Hits	101
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

ADA15_MOUSE
NC score	0.184012 (rank : 654)	θ value	1.09739e-05 (rank : 431)
Query Neighborhood Hits	905	Target Neighborhood Hits	324	Shared Neighborhood Hits	224
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

FSTL3_HUMAN
NC score	0.182014 (rank : 655)	θ value	0.279714 (rank : 695)
Query Neighborhood Hits	905	Target Neighborhood Hits	162	Shared Neighborhood Hits	107
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

CORIN_MOUSE
NC score	0.181750 (rank : 656)	θ value	4.45536e-07 (rank : 388)
Query Neighborhood Hits	905	Target Neighborhood Hits	451	Shared Neighborhood Hits	220
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

ADA23_HUMAN
NC score	0.179064 (rank : 657)	θ value	0.0330416 (rank : 610)
Query Neighborhood Hits	905	Target Neighborhood Hits	235	Shared Neighborhood Hits	182
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

LRP3_HUMAN
NC score	0.176939 (rank : 658)	θ value	0.0431538 (rank : 624)
Query Neighborhood Hits	905	Target Neighborhood Hits	280	Shared Neighborhood Hits	140
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

CLR59_HUMAN
NC score	0.176148 (rank : 659)	θ value	0.00390308 (rank : 547)
Query Neighborhood Hits	905	Target Neighborhood Hits	163	Shared Neighborhood Hits	141
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

FSTL3_MOUSE
NC score	0.175899 (rank : 660)	θ value	0.00298849 (rank : 540)
Query Neighborhood Hits	905	Target Neighborhood Hits	152	Shared Neighborhood Hits	101
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

MT3_MOUSE
NC score	0.173611 (rank : 661)	θ value	θ > 10 (rank : 1026)
Query Neighborhood Hits	905	Target Neighborhood Hits	68	Shared Neighborhood Hits	54
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

APR3_HUMAN
NC score	0.173576 (rank : 662)	θ value	0.279714 (rank : 692)
Query Neighborhood Hits	905	Target Neighborhood Hits	50	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

ADA23_MOUSE
NC score	0.172628 (rank : 663)	θ value	0.813845 (rank : 739)
Query Neighborhood Hits	905	Target Neighborhood Hits	245	Shared Neighborhood Hits	196
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

NRG2_HUMAN
NC score	0.171938 (rank : 664)	θ value	0.0431538 (rank : 626)
Query Neighborhood Hits	905	Target Neighborhood Hits	419	Shared Neighborhood Hits	119
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

PHXR5_MOUSE
NC score	0.171204 (rank : 665)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	74
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

ANKR9_MOUSE
NC score	0.170780 (rank : 666)	θ value	0.279714 (rank : 691)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ADA19_MOUSE
NC score	0.169157 (rank : 667)	θ value	0.163984 (rank : 663)
Query Neighborhood Hits	905	Target Neighborhood Hits	315	Shared Neighborhood Hits	205
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA15_HUMAN
NC score	0.168183 (rank : 668)	θ value	0.00298849 (rank : 538)
Query Neighborhood Hits	905	Target Neighborhood Hits	288	Shared Neighborhood Hits	213
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

MCSP_MOUSE
NC score	0.167434 (rank : 669)	θ value	0.00665767 (rank : 565)
Query Neighborhood Hits	905	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MT4_MOUSE
NC score	0.166834 (rank : 670)	θ value	3.0926 (rank : 809)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	74
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

ADA19_HUMAN
NC score	0.166748 (rank : 671)	θ value	0.00134147 (rank : 513)
Query Neighborhood Hits	905	Target Neighborhood Hits	381	Shared Neighborhood Hits	192
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

TRPV3_MOUSE
NC score	0.165509 (rank : 672)	θ value	0.00390308 (rank : 551)
Query Neighborhood Hits	905	Target Neighborhood Hits	188	Shared Neighborhood Hits	129
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

ADAM9_MOUSE
NC score	0.162548 (rank : 673)	θ value	0.00035302 (rank : 481)
Query Neighborhood Hits	905	Target Neighborhood Hits	325	Shared Neighborhood Hits	203
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

PGH1_HUMAN
NC score	0.161264 (rank : 674)	θ value	1.38821 (rank : 772)
Query Neighborhood Hits	905	Target Neighborhood Hits	91	Shared Neighborhood Hits	78
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

WFDC3_HUMAN
NC score	0.161139 (rank : 675)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	905	Target Neighborhood Hits	138	Shared Neighborhood Hits	102
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

DDEF1_MOUSE
NC score	0.160722 (rank : 676)	θ value	0.00102713 (rank : 509)
Query Neighborhood Hits	905	Target Neighborhood Hits	592	Shared Neighborhood Hits	195
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

MT3_HUMAN
NC score	0.160716 (rank : 677)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	905	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

LCE2C_HUMAN
NC score	0.160632 (rank : 678)	θ value	θ > 10 (rank : 1000)
Query Neighborhood Hits	905	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

TPA_MOUSE
NC score	0.160284 (rank : 679)	θ value	0.000786445 (rank : 503)
Query Neighborhood Hits	905	Target Neighborhood Hits	335	Shared Neighborhood Hits	179
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ADA33_HUMAN
NC score	0.160267 (rank : 680)	θ value	2.61198e-07 (rank : 371)
Query Neighborhood Hits	905	Target Neighborhood Hits	264	Shared Neighborhood Hits	178
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

TRPV3_HUMAN
NC score	0.160165 (rank : 681)	θ value	0.00509761 (rank : 559)
Query Neighborhood Hits	905	Target Neighborhood Hits	198	Shared Neighborhood Hits	140
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TPA_HUMAN
NC score	0.159963 (rank : 682)	θ value	4.1701e-05 (rank : 455)
Query Neighborhood Hits	905	Target Neighborhood Hits	324	Shared Neighborhood Hits	170
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ST14_MOUSE
NC score	0.159834 (rank : 683)	θ value	0.00665767 (rank : 572)
Query Neighborhood Hits	905	Target Neighborhood Hits	419	Shared Neighborhood Hits	207
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

VASN_HUMAN
NC score	0.159301 (rank : 684)	θ value	0.00102713 (rank : 511)
Query Neighborhood Hits	905	Target Neighborhood Hits	449	Shared Neighborhood Hits	143
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

CD320_HUMAN
NC score	0.158886 (rank : 685)	θ value	0.0431538 (rank : 622)
Query Neighborhood Hits	905	Target Neighborhood Hits	103	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

ST14_HUMAN
NC score	0.158800 (rank : 686)	θ value	0.365318 (rank : 719)
Query Neighborhood Hits	905	Target Neighborhood Hits	409	Shared Neighborhood Hits	194
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ADA18_MOUSE
NC score	0.158304 (rank : 687)	θ value	0.000121331 (rank : 465)
Query Neighborhood Hits	905	Target Neighborhood Hits	227	Shared Neighborhood Hits	180
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

EREG_HUMAN
NC score	0.156834 (rank : 688)	θ value	0.365318 (rank : 709)
Query Neighborhood Hits	905	Target Neighborhood Hits	73	Shared Neighborhood Hits	64
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ADA33_MOUSE
NC score	0.156566 (rank : 689)	θ value	4.0297e-08 (rank : 342)
Query Neighborhood Hits	905	Target Neighborhood Hits	231	Shared Neighborhood Hits	174
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CO9_MOUSE
NC score	0.155877 (rank : 690)	θ value	0.279714 (rank : 693)
Query Neighborhood Hits	905	Target Neighborhood Hits	153	Shared Neighborhood Hits	102
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

KR124_HUMAN
NC score	0.155748 (rank : 691)	θ value	0.00228821 (rank : 534)
Query Neighborhood Hits	905	Target Neighborhood Hits	124	Shared Neighborhood Hits	94
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

LCE2A_HUMAN
NC score	0.155060 (rank : 692)	θ value	0.279714 (rank : 698)
Query Neighborhood Hits	905	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

C1RA_MOUSE
NC score	0.154163 (rank : 693)	θ value	0.0736092 (rank : 635)
Query Neighborhood Hits	905	Target Neighborhood Hits	379	Shared Neighborhood Hits	171
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

ADA10_HUMAN
NC score	0.153981 (rank : 694)	θ value	0.00228821 (rank : 529)
Query Neighborhood Hits	905	Target Neighborhood Hits	189	Shared Neighborhood Hits	140
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

FST_MOUSE
NC score	0.152590 (rank : 695)	θ value	0.62314 (rank : 736)
Query Neighborhood Hits	905	Target Neighborhood Hits	146	Shared Neighborhood Hits	91
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ADAM9_HUMAN
NC score	0.152327 (rank : 696)	θ value	0.000270298 (rank : 480)
Query Neighborhood Hits	905	Target Neighborhood Hits	243	Shared Neighborhood Hits	177
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

TNR25_HUMAN
NC score	0.152064 (rank : 697)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	905	Target Neighborhood Hits	172	Shared Neighborhood Hits	85
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

C1RB_MOUSE
NC score	0.151741 (rank : 698)	θ value	0.0736092 (rank : 636)
Query Neighborhood Hits	905	Target Neighborhood Hits	380	Shared Neighborhood Hits	170
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

LCE2D_HUMAN
NC score	0.151037 (rank : 699)	θ value	5.27518 (rank : 843)
Query Neighborhood Hits	905	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

ESM1_MOUSE
NC score	0.150586 (rank : 700)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	905	Target Neighborhood Hits	107	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ASTN_HUMAN
NC score	0.148832 (rank : 701)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	905	Target Neighborhood Hits	105	Shared Neighborhood Hits	83
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

VEGFC_HUMAN
NC score	0.148554 (rank : 702)	θ value	1.38821 (rank : 775)
Query Neighborhood Hits	905	Target Neighborhood Hits	128	Shared Neighborhood Hits	104
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ASTN_MOUSE
NC score	0.147496 (rank : 703)	θ value	5.27518 (rank : 830)
Query Neighborhood Hits	905	Target Neighborhood Hits	98	Shared Neighborhood Hits	78
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

LCE4A_HUMAN
NC score	0.147276 (rank : 704)	θ value	θ > 10 (rank : 1002)
Query Neighborhood Hits	905	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

TRPV1_MOUSE
NC score	0.147081 (rank : 705)	θ value	1.06291 (rank : 764)
Query Neighborhood Hits	905	Target Neighborhood Hits	189	Shared Neighborhood Hits	153
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

ADA10_MOUSE
NC score	0.147012 (rank : 706)	θ value	0.0148317 (rank : 585)
Query Neighborhood Hits	905	Target Neighborhood Hits	194	Shared Neighborhood Hits	141
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA17_HUMAN
NC score	0.146546 (rank : 707)	θ value	5.27518 (rank : 829)
Query Neighborhood Hits	905	Target Neighborhood Hits	223	Shared Neighborhood Hits	154
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADAM2_MOUSE
NC score	0.146520 (rank : 708)	θ value	1.38821 (rank : 766)
Query Neighborhood Hits	905	Target Neighborhood Hits	209	Shared Neighborhood Hits	162
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

LCE2B_HUMAN
NC score	0.146499 (rank : 709)	θ value	6.88961 (rank : 875)
Query Neighborhood Hits	905	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

VASN_MOUSE
NC score	0.145556 (rank : 710)	θ value	0.0330416 (rank : 619)
Query Neighborhood Hits	905	Target Neighborhood Hits	426	Shared Neighborhood Hits	130
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ADAM7_HUMAN
NC score	0.144548 (rank : 711)	θ value	2.36792 (rank : 786)
Query Neighborhood Hits	905	Target Neighborhood Hits	221	Shared Neighborhood Hits	171
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADA30_HUMAN
NC score	0.144455 (rank : 712)	θ value	0.00175202 (rank : 519)
Query Neighborhood Hits	905	Target Neighborhood Hits	391	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

LRP10_HUMAN
NC score	0.144328 (rank : 713)	θ value	0.279714 (rank : 699)
Query Neighborhood Hits	905	Target Neighborhood Hits	197	Shared Neighborhood Hits	103
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

CO8B_HUMAN
NC score	0.144274 (rank : 714)	θ value	0.125558 (rank : 659)
Query Neighborhood Hits	905	Target Neighborhood Hits	199	Shared Neighborhood Hits	100
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

TRPV1_HUMAN
NC score	0.143839 (rank : 715)	θ value	5.27518 (rank : 852)
Query Neighborhood Hits	905	Target Neighborhood Hits	184	Shared Neighborhood Hits	145
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

LRP10_MOUSE
NC score	0.142861 (rank : 716)	θ value	0.21417 (rank : 683)
Query Neighborhood Hits	905	Target Neighborhood Hits	169	Shared Neighborhood Hits	100
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

CO9_HUMAN
NC score	0.141865 (rank : 717)	θ value	6.88961 (rank : 862)
Query Neighborhood Hits	905	Target Neighborhood Hits	147	Shared Neighborhood Hits	98
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

TRPV2_HUMAN
NC score	0.141798 (rank : 718)	θ value	0.0113563 (rank : 584)
Query Neighborhood Hits	905	Target Neighborhood Hits	130	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

ADA22_MOUSE
NC score	0.141654 (rank : 719)	θ value	6.88961 (rank : 855)
Query Neighborhood Hits	905	Target Neighborhood Hits	225	Shared Neighborhood Hits	156
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

KR122_HUMAN
NC score	0.141425 (rank : 720)	θ value	0.813845 (rank : 745)
Query Neighborhood Hits	905	Target Neighborhood Hits	97	Shared Neighborhood Hits	78
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

ABTB1_MOUSE
NC score	0.141142 (rank : 721)	θ value	5.27518 (rank : 828)
Query Neighborhood Hits	905	Target Neighborhood Hits	349	Shared Neighborhood Hits	175
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

MKS3_MOUSE
NC score	0.140693 (rank : 722)	θ value	1.81305 (rank : 782)
Query Neighborhood Hits	905	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

ANKR9_HUMAN
NC score	0.140283 (rank : 723)	θ value	0.62314 (rank : 732)
Query Neighborhood Hits	905	Target Neighborhood Hits	99	Shared Neighborhood Hits	97
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

TNR16_HUMAN
NC score	0.139931 (rank : 724)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	905	Target Neighborhood Hits	183	Shared Neighborhood Hits	111
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

BAT4_MOUSE
NC score	0.139818 (rank : 725)	θ value	4.03905 (rank : 815)
Query Neighborhood Hits	905	Target Neighborhood Hits	171	Shared Neighborhood Hits	120
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

ADM1A_MOUSE
NC score	0.139426 (rank : 726)	θ value	1.38821 (rank : 767)
Query Neighborhood Hits	905	Target Neighborhood Hits	230	Shared Neighborhood Hits	187
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA12_HUMAN
NC score	0.138825 (rank : 727)	θ value	0.0113563 (rank : 577)
Query Neighborhood Hits	905	Target Neighborhood Hits	224	Shared Neighborhood Hits	152
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

GNPTA_HUMAN
NC score	0.138719 (rank : 728)	θ value	3.77169e-06 (rank : 417)
Query Neighborhood Hits	905	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

LORI_MOUSE
NC score	0.137579 (rank : 729)	θ value	0.47712 (rank : 724)
Query Neighborhood Hits	905	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

FST_HUMAN
NC score	0.137449 (rank : 730)	θ value	5.27518 (rank : 837)
Query Neighborhood Hits	905	Target Neighborhood Hits	129	Shared Neighborhood Hits	73
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ADA18_HUMAN
NC score	0.137199 (rank : 731)	θ value	0.0252991 (rank : 599)
Query Neighborhood Hits	905	Target Neighborhood Hits	184	Shared Neighborhood Hits	148
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

C1R_HUMAN
NC score	0.136773 (rank : 732)	θ value	1.06291 (rank : 756)
Query Neighborhood Hits	905	Target Neighborhood Hits	364	Shared Neighborhood Hits	161
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

CO8A_HUMAN
NC score	0.136134 (rank : 733)	θ value	1.81305 (rank : 776)
Query Neighborhood Hits	905	Target Neighborhood Hits	200	Shared Neighborhood Hits	110
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

LRP12_HUMAN
NC score	0.135999 (rank : 734)	θ value	2.36792 (rank : 789)
Query Neighborhood Hits	905	Target Neighborhood Hits	205	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

GNPTA_MOUSE
NC score	0.135979 (rank : 735)	θ value	9.29e-05 (rank : 463)
Query Neighborhood Hits	905	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

ADA21_MOUSE
NC score	0.135920 (rank : 736)	θ value	0.125558 (rank : 656)
Query Neighborhood Hits	905	Target Neighborhood Hits	172	Shared Neighborhood Hits	132
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

LRP12_MOUSE
NC score	0.135333 (rank : 737)	θ value	1.06291 (rank : 758)
Query Neighborhood Hits	905	Target Neighborhood Hits	180	Shared Neighborhood Hits	102
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

MKS3_HUMAN
NC score	0.135033 (rank : 738)	θ value	1.81305 (rank : 781)
Query Neighborhood Hits	905	Target Neighborhood Hits	79	Shared Neighborhood Hits	73
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

ADA28_MOUSE
NC score	0.134893 (rank : 739)	θ value	1.06291 (rank : 752)
Query Neighborhood Hits	905	Target Neighborhood Hits	241	Shared Neighborhood Hits	172
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA28_HUMAN
NC score	0.134320 (rank : 740)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	905	Target Neighborhood Hits	244	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA22_HUMAN
NC score	0.132851 (rank : 741)	θ value	1.38821 (rank : 765)
Query Neighborhood Hits	905	Target Neighborhood Hits	211	Shared Neighborhood Hits	146
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

CO8A_MOUSE
NC score	0.132658 (rank : 742)	θ value	0.125558 (rank : 658)
Query Neighborhood Hits	905	Target Neighborhood Hits	182	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ADA32_HUMAN
NC score	0.132420 (rank : 743)	θ value	0.00869519 (rank : 573)
Query Neighborhood Hits	905	Target Neighborhood Hits	216	Shared Neighborhood Hits	165
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

MEP1B_MOUSE
NC score	0.132313 (rank : 744)	θ value	0.279714 (rank : 701)
Query Neighborhood Hits	905	Target Neighborhood Hits	127	Shared Neighborhood Hits	91
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MASP2_HUMAN
NC score	0.131215 (rank : 745)	θ value	0.0193708 (rank : 597)
Query Neighborhood Hits	905	Target Neighborhood Hits	364	Shared Neighborhood Hits	156
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

ADA25_MOUSE
NC score	0.130867 (rank : 746)	θ value	0.00509761 (rank : 553)
Query Neighborhood Hits	905	Target Neighborhood Hits	213	Shared Neighborhood Hits	161
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

VEGFC_MOUSE
NC score	0.130464 (rank : 747)	θ value	0.21417 (rank : 689)
Query Neighborhood Hits	905	Target Neighborhood Hits	119	Shared Neighborhood Hits	91
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CS1A_MOUSE
NC score	0.130083 (rank : 748)	θ value	8.99809 (rank : 888)
Query Neighborhood Hits	905	Target Neighborhood Hits	360	Shared Neighborhood Hits	152
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
NC score	0.129173 (rank : 749)	θ value	6.88961 (rank : 866)
Query Neighborhood Hits	905	Target Neighborhood Hits	361	Shared Neighborhood Hits	152
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

TNR16_MOUSE
NC score	0.128997 (rank : 750)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	905	Target Neighborhood Hits	178	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

MASP2_MOUSE
NC score	0.128967 (rank : 751)	θ value	0.47712 (rank : 726)
Query Neighborhood Hits	905	Target Neighborhood Hits	382	Shared Neighborhood Hits	163
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

ADAM2_HUMAN
NC score	0.128938 (rank : 752)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	905	Target Neighborhood Hits	175	Shared Neighborhood Hits	137
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADA24_MOUSE
NC score	0.128507 (rank : 753)	θ value	0.0961366 (rank : 647)
Query Neighborhood Hits	905	Target Neighborhood Hits	230	Shared Neighborhood Hits	178
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

MT4_HUMAN
NC score	0.127483 (rank : 754)	θ value	8.99809 (rank : 900)
Query Neighborhood Hits	905	Target Neighborhood Hits	83	Shared Neighborhood Hits	57
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

ADA21_HUMAN
NC score	0.127191 (rank : 755)	θ value	3.0926 (rank : 795)
Query Neighborhood Hits	905	Target Neighborhood Hits	181	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

LCE3B_HUMAN
NC score	0.126662 (rank : 756)	θ value	θ > 10 (rank : 1001)
Query Neighborhood Hits	905	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

EPGN_MOUSE
NC score	0.125155 (rank : 757)	θ value	6.88961 (rank : 870)
Query Neighborhood Hits	905	Target Neighborhood Hits	63	Shared Neighborhood Hits	56
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

ADA32_MOUSE
NC score	0.124797 (rank : 758)	θ value	1.06291 (rank : 753)
Query Neighborhood Hits	905	Target Neighborhood Hits	219	Shared Neighborhood Hits	172
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

C1S_HUMAN
NC score	0.124775 (rank : 759)	θ value	6.88961 (rank : 858)
Query Neighborhood Hits	905	Target Neighborhood Hits	359	Shared Neighborhood Hits	158
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

ADM1B_MOUSE
NC score	0.124151 (rank : 760)	θ value	0.0252991 (rank : 600)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	152
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA12_MOUSE
NC score	0.122556 (rank : 761)	θ value	0.279714 (rank : 690)
Query Neighborhood Hits	905	Target Neighborhood Hits	474	Shared Neighborhood Hits	148
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

MASP1_HUMAN
NC score	0.121676 (rank : 762)	θ value	5.27518 (rank : 845)
Query Neighborhood Hits	905	Target Neighborhood Hits	369	Shared Neighborhood Hits	157
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

TMPS6_HUMAN
NC score	0.121453 (rank : 763)	θ value	0.000158464 (rank : 473)
Query Neighborhood Hits	905	Target Neighborhood Hits	338	Shared Neighborhood Hits	149
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ABTB1_HUMAN
NC score	0.121377 (rank : 764)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	905	Target Neighborhood Hits	325	Shared Neighborhood Hits	159
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

RSNL2_HUMAN
NC score	0.120290 (rank : 765)	θ value	8.99809 (rank : 903)
Query Neighborhood Hits	905	Target Neighborhood Hits	136	Shared Neighborhood Hits	113
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

MASP1_MOUSE
NC score	0.119482 (rank : 766)	θ value	5.27518 (rank : 846)
Query Neighborhood Hits	905	Target Neighborhood Hits	364	Shared Neighborhood Hits	158
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

ADA17_MOUSE
NC score	0.119023 (rank : 767)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	905	Target Neighborhood Hits	201	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADAM7_MOUSE
NC score	0.118243 (rank : 768)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	905	Target Neighborhood Hits	200	Shared Neighborhood Hits	152
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

BAT4_HUMAN
NC score	0.118123 (rank : 769)	θ value	8.99809 (rank : 887)
Query Neighborhood Hits	905	Target Neighborhood Hits	157	Shared Neighborhood Hits	111
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

LCE5A_HUMAN
NC score	0.114293 (rank : 770)	θ value	θ > 10 (rank : 1003)
Query Neighborhood Hits	905	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

BTC_MOUSE
NC score	0.114275 (rank : 771)	θ value	5.27518 (rank : 833)
Query Neighborhood Hits	905	Target Neighborhood Hits	67	Shared Neighborhood Hits	59
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

TNR9_HUMAN
NC score	0.113962 (rank : 772)	θ value	0.279714 (rank : 702)
Query Neighborhood Hits	905	Target Neighborhood Hits	166	Shared Neighborhood Hits	88
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TMPS6_MOUSE
NC score	0.113694 (rank : 773)	θ value	0.0148317 (rank : 592)
Query Neighborhood Hits	905	Target Neighborhood Hits	341	Shared Neighborhood Hits	150
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

SHBG_HUMAN
NC score	0.113594 (rank : 774)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	905	Target Neighborhood Hits	45	Shared Neighborhood Hits	35
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

ADA29_HUMAN
NC score	0.112239 (rank : 775)	θ value	2.36792 (rank : 785)
Query Neighborhood Hits	905	Target Neighborhood Hits	247	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

RSNL2_MOUSE
NC score	0.110585 (rank : 776)	θ value	0.0252991 (rank : 607)
Query Neighborhood Hits	905	Target Neighborhood Hits	129	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSPO3_HUMAN
NC score	0.109954 (rank : 777)	θ value	6.88961 (rank : 880)
Query Neighborhood Hits	905	Target Neighborhood Hits	128	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

SHBG_MOUSE
NC score	0.109772 (rank : 778)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	905	Target Neighborhood Hits	50	Shared Neighborhood Hits	40
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

PAPPA_HUMAN
NC score	0.109021 (rank : 779)	θ value	0.0961366 (rank : 652)
Query Neighborhood Hits	905	Target Neighborhood Hits	161	Shared Neighborhood Hits	86
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

TNR14_HUMAN
NC score	0.108158 (rank : 780)	θ value	3.0926 (rank : 813)
Query Neighborhood Hits	905	Target Neighborhood Hits	149	Shared Neighborhood Hits	87
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

EPGN_HUMAN
NC score	0.107784 (rank : 781)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	905	Target Neighborhood Hits	59	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

ZNFX1_HUMAN
NC score	0.107475 (rank : 782)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	905	Target Neighborhood Hits	308	Shared Neighborhood Hits	135
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

PAPPA_MOUSE
NC score	0.107301 (rank : 783)	θ value	0.365318 (rank : 717)
Query Neighborhood Hits	905	Target Neighborhood Hits	153	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

TRPV2_MOUSE
NC score	0.106639 (rank : 784)	θ value	0.21417 (rank : 688)
Query Neighborhood Hits	905	Target Neighborhood Hits	111	Shared Neighborhood Hits	92
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TNR4_MOUSE
NC score	0.104220 (rank : 785)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	905	Target Neighborhood Hits	137	Shared Neighborhood Hits	76
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

SPR2D_MOUSE
NC score	0.102880 (rank : 786)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	905	Target Neighborhood Hits	61	Shared Neighborhood Hits	25
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

DKK3_MOUSE
NC score	0.102567 (rank : 787)	θ value	1.81305 (rank : 777)
Query Neighborhood Hits	905	Target Neighborhood Hits	83	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

KR111_HUMAN
NC score	0.102000 (rank : 788)	θ value	θ > 10 (rank : 991)
Query Neighborhood Hits	905	Target Neighborhood Hits	90	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

GP128_MOUSE
NC score	0.101542 (rank : 789)	θ value	0.279714 (rank : 696)
Query Neighborhood Hits	905	Target Neighborhood Hits	141	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

TNR8_MOUSE
NC score	0.101077 (rank : 790)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	905	Target Neighborhood Hits	208	Shared Neighborhood Hits	89
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

ZNFX1_MOUSE
NC score	0.101033 (rank : 791)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	905	Target Neighborhood Hits	407	Shared Neighborhood Hits	139
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

KR123_HUMAN
NC score	0.100743 (rank : 792)	θ value	0.21417 (rank : 680)
Query Neighborhood Hits	905	Target Neighborhood Hits	75	Shared Neighborhood Hits	56
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

BTC_HUMAN
NC score	0.100281 (rank : 793)	θ value	6.88961 (rank : 857)
Query Neighborhood Hits	905	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

HBEGF_HUMAN
NC score	0.099508 (rank : 794)	θ value	6.88961 (rank : 873)
Query Neighborhood Hits	905	Target Neighborhood Hits	61	Shared Neighborhood Hits	53
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

AD26A_MOUSE
NC score	0.099010 (rank : 795)	θ value	6.88961 (rank : 854)
Query Neighborhood Hits	905	Target Neighborhood Hits	165	Shared Neighborhood Hits	122
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

CYR61_MOUSE
NC score	0.098757 (rank : 796)	θ value	0.163984 (rank : 665)
Query Neighborhood Hits	905	Target Neighborhood Hits	156	Shared Neighborhood Hits	82
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

TNR7_HUMAN
NC score	0.098601 (rank : 797)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

EREG_MOUSE
NC score	0.098376 (rank : 798)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	905	Target Neighborhood Hits	65	Shared Neighborhood Hits	53
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

UROK_HUMAN
NC score	0.098014 (rank : 799)	θ value	0.0431538 (rank : 628)
Query Neighborhood Hits	905	Target Neighborhood Hits	272	Shared Neighborhood Hits	121
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

RSPO3_MOUSE
NC score	0.097662 (rank : 800)	θ value	1.38821 (rank : 773)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	72
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

TRPV4_HUMAN
NC score	0.097476 (rank : 801)	θ value	0.0563607 (rank : 633)
Query Neighborhood Hits	905	Target Neighborhood Hits	150	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TNR4_HUMAN
NC score	0.097439 (rank : 802)	θ value	8.99809 (rank : 905)
Query Neighborhood Hits	905	Target Neighborhood Hits	152	Shared Neighborhood Hits	74
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

CMTA1_HUMAN
NC score	0.097419 (rank : 803)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	905	Target Neighborhood Hits	217	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

NRG3_MOUSE
NC score	0.096522 (rank : 804)	θ value	0.365318 (rank : 715)
Query Neighborhood Hits	905	Target Neighborhood Hits	132	Shared Neighborhood Hits	77
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

UROK_MOUSE
NC score	0.096271 (rank : 805)	θ value	0.0736092 (rank : 646)
Query Neighborhood Hits	905	Target Neighborhood Hits	273	Shared Neighborhood Hits	125
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

CMTA2_HUMAN
NC score	0.095986 (rank : 806)	θ value	0.163984 (rank : 664)
Query Neighborhood Hits	905	Target Neighborhood Hits	199	Shared Neighborhood Hits	98
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CYR61_HUMAN
NC score	0.095350 (rank : 807)	θ value	0.365318 (rank : 705)
Query Neighborhood Hits	905	Target Neighborhood Hits	159	Shared Neighborhood Hits	84
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

GP128_HUMAN
NC score	0.094687 (rank : 808)	θ value	3.0926 (rank : 805)
Query Neighborhood Hits	905	Target Neighborhood Hits	135	Shared Neighborhood Hits	52
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

FINC_MOUSE
NC score	0.094384 (rank : 809)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	905	Target Neighborhood Hits	309	Shared Neighborhood Hits	69
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

SPR2G_MOUSE
NC score	0.094229 (rank : 810)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	905	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

FINC_HUMAN
NC score	0.093810 (rank : 811)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	905	Target Neighborhood Hits	302	Shared Neighborhood Hits	62
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

NRG3_HUMAN
NC score	0.093289 (rank : 812)	θ value	0.365318 (rank : 714)
Query Neighborhood Hits	905	Target Neighborhood Hits	119	Shared Neighborhood Hits	69
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

TGFA_HUMAN
NC score	0.092560 (rank : 813)	θ value	8.99809 (rank : 904)
Query Neighborhood Hits	905	Target Neighborhood Hits	61	Shared Neighborhood Hits	55
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

DKK3_HUMAN
NC score	0.092455 (rank : 814)	θ value	3.0926 (rank : 803)
Query Neighborhood Hits	905	Target Neighborhood Hits	74	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

BAI1_HUMAN
NC score	0.091933 (rank : 815)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	905	Target Neighborhood Hits	375	Shared Neighborhood Hits	81
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CT127_HUMAN
NC score	0.090835 (rank : 816)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	905	Target Neighborhood Hits	67	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

ADA20_HUMAN
NC score	0.089964 (rank : 817)	θ value	3.0926 (rank : 794)
Query Neighborhood Hits	905	Target Neighborhood Hits	143	Shared Neighborhood Hits	95
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

MT1B_HUMAN
NC score	0.089421 (rank : 818)	θ value	θ > 10 (rank : 1018)
Query Neighborhood Hits	905	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

CTGF_HUMAN
NC score	0.089365 (rank : 819)	θ value	0.813845 (rank : 743)
Query Neighborhood Hits	905	Target Neighborhood Hits	128	Shared Neighborhood Hits	68
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

BAI3_MOUSE
NC score	0.089354 (rank : 820)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	905	Target Neighborhood Hits	250	Shared Neighborhood Hits	78
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

RSPO4_HUMAN
NC score	0.088454 (rank : 821)	θ value	5.27518 (rank : 849)
Query Neighborhood Hits	905	Target Neighborhood Hits	110	Shared Neighborhood Hits	76
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

MT1A_HUMAN
NC score	0.086955 (rank : 822)	θ value	θ > 10 (rank : 1017)
Query Neighborhood Hits	905	Target Neighborhood Hits	74	Shared Neighborhood Hits	52
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

BAI3_HUMAN
NC score	0.086879 (rank : 823)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	905	Target Neighborhood Hits	246	Shared Neighborhood Hits	71
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

TRPV4_MOUSE
NC score	0.086086 (rank : 824)	θ value	0.0736092 (rank : 645)
Query Neighborhood Hits	905	Target Neighborhood Hits	117	Shared Neighborhood Hits	76
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

MEP1B_HUMAN
NC score	0.086032 (rank : 825)	θ value	0.279714 (rank : 700)
Query Neighborhood Hits	905	Target Neighborhood Hits	98	Shared Neighborhood Hits	63
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

BAI1_MOUSE
NC score	0.085942 (rank : 826)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	905	Target Neighborhood Hits	340	Shared Neighborhood Hits	78
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_MOUSE
NC score	0.085840 (rank : 827)	θ value	3.0926 (rank : 797)
Query Neighborhood Hits	905	Target Neighborhood Hits	323	Shared Neighborhood Hits	76
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TNR11_HUMAN
NC score	0.085719 (rank : 828)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	905	Target Neighborhood Hits	135	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

CMTA2_MOUSE
NC score	0.085621 (rank : 829)	θ value	0.21417 (rank : 677)
Query Neighborhood Hits	905	Target Neighborhood Hits	216	Shared Neighborhood Hits	83
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CHRD_HUMAN
NC score	0.085352 (rank : 830)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

TNR5_MOUSE
NC score	0.085093 (rank : 831)	θ value	0.47712 (rank : 730)
Query Neighborhood Hits	905	Target Neighborhood Hits	131	Shared Neighborhood Hits	72
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

SPR2H_MOUSE
NC score	0.084457 (rank : 832)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	905	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

BAI2_HUMAN
NC score	0.084335 (rank : 833)	θ value	5.27518 (rank : 832)
Query Neighborhood Hits	905	Target Neighborhood Hits	332	Shared Neighborhood Hits	74
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TNR9_MOUSE
NC score	0.084139 (rank : 834)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	905	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

CTGF_MOUSE
NC score	0.083955 (rank : 835)	θ value	5.27518 (rank : 835)
Query Neighborhood Hits	905	Target Neighborhood Hits	124	Shared Neighborhood Hits	66
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

TNR8_HUMAN
NC score	0.083737 (rank : 836)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	905	Target Neighborhood Hits	198	Shared Neighborhood Hits	87
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

SPR2B_MOUSE
NC score	0.083428 (rank : 837)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	905	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

NEU1_MOUSE
NC score	0.083342 (rank : 838)	θ value	0.47712 (rank : 728)
Query Neighborhood Hits	905	Target Neighborhood Hits	64	Shared Neighborhood Hits	56
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

KR261_HUMAN
NC score	0.082864 (rank : 839)	θ value	5.27518 (rank : 841)
Query Neighborhood Hits	905	Target Neighborhood Hits	65	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

KR241_HUMAN
NC score	0.082306 (rank : 840)	θ value	θ > 10 (rank : 997)
Query Neighborhood Hits	905	Target Neighborhood Hits	71	Shared Neighborhood Hits	54
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

MT1X_HUMAN
NC score	0.081736 (rank : 841)	θ value	θ > 10 (rank : 1022)
Query Neighborhood Hits	905	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

PAP2_HUMAN
NC score	0.080892 (rank : 842)	θ value	0.00228821 (rank : 537)
Query Neighborhood Hits	905	Target Neighborhood Hits	106	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

SPR2F_HUMAN
NC score	0.080532 (rank : 843)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	905	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

CHRD_MOUSE
NC score	0.080201 (rank : 844)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CRDL2_MOUSE
NC score	0.080112 (rank : 845)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	905	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

TSG6_MOUSE
NC score	0.079659 (rank : 846)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	905	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSG6_HUMAN
NC score	0.079552 (rank : 847)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	905	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

GP113_HUMAN
NC score	0.079133 (rank : 848)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

TNR23_MOUSE
NC score	0.078803 (rank : 849)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	905	Target Neighborhood Hits	114	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

MT2_MOUSE
NC score	0.078771 (rank : 850)	θ value	θ > 10 (rank : 1024)
Query Neighborhood Hits	905	Target Neighborhood Hits	81	Shared Neighborhood Hits	49
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

CFAI_MOUSE
NC score	0.078033 (rank : 851)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	905	Target Neighborhood Hits	290	Shared Neighborhood Hits	99
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

GP126_HUMAN
NC score	0.078001 (rank : 852)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	905	Target Neighborhood Hits	187	Shared Neighborhood Hits	47
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

PROP_MOUSE
NC score	0.077987 (rank : 853)	θ value	0.000786445 (rank : 502)
Query Neighborhood Hits	905	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

CRDL2_HUMAN
NC score	0.077984 (rank : 854)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	905	Target Neighborhood Hits	99	Shared Neighborhood Hits	56
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

RSPO4_MOUSE
NC score	0.077733 (rank : 855)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	905	Target Neighborhood Hits	110	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

LCE3C_HUMAN
NC score	0.077561 (rank : 856)	θ value	6.88961 (rank : 876)
Query Neighborhood Hits	905	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

TMPS7_HUMAN
NC score	0.076149 (rank : 857)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	905	Target Neighborhood Hits	275	Shared Neighborhood Hits	98
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

GP144_HUMAN
NC score	0.075952 (rank : 858)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	905	Target Neighborhood Hits	108	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

TMPS7_MOUSE
NC score	0.075830 (rank : 859)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	905	Target Neighborhood Hits	275	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

MFRP_HUMAN
NC score	0.075800 (rank : 860)	θ value	θ > 10 (rank : 1015)
Query Neighborhood Hits	905	Target Neighborhood Hits	165	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

TGFA_MOUSE
NC score	0.075524 (rank : 861)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	905	Target Neighborhood Hits	62	Shared Neighborhood Hits	53
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

WISP2_HUMAN
NC score	0.074804 (rank : 862)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	905	Target Neighborhood Hits	126	Shared Neighborhood Hits	55
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

CFAI_HUMAN
NC score	0.074780 (rank : 863)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	905	Target Neighborhood Hits	289	Shared Neighborhood Hits	90
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

IDD_HUMAN
NC score	0.073999 (rank : 864)	θ value	θ > 10 (rank : 989)
Query Neighborhood Hits	905	Target Neighborhood Hits	127	Shared Neighborhood Hits	53
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

GP133_HUMAN
NC score	0.073562 (rank : 865)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	905	Target Neighborhood Hits	115	Shared Neighborhood Hits	19
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

NOV_HUMAN
NC score	0.073292 (rank : 866)	θ value	0.62314 (rank : 738)
Query Neighborhood Hits	905	Target Neighborhood Hits	128	Shared Neighborhood Hits	71
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

MT1_MOUSE
NC score	0.073199 (rank : 867)	θ value	θ > 10 (rank : 1023)
Query Neighborhood Hits	905	Target Neighborhood Hits	72	Shared Neighborhood Hits	45
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

GP112_HUMAN
NC score	0.072689 (rank : 868)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	905	Target Neighborhood Hits	441	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

HBEGF_MOUSE
NC score	0.072311 (rank : 869)	θ value	5.27518 (rank : 838)
Query Neighborhood Hits	905	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

ANKF1_HUMAN
NC score	0.072124 (rank : 870)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	905	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

LPHN2_HUMAN
NC score	0.071893 (rank : 871)	θ value	θ > 10 (rank : 1005)
Query Neighborhood Hits	905	Target Neighborhood Hits	136	Shared Neighborhood Hits	22
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LPHN3_HUMAN
NC score	0.071427 (rank : 872)	θ value	θ > 10 (rank : 1006)
Query Neighborhood Hits	905	Target Neighborhood Hits	139	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LPHN1_HUMAN
NC score	0.070748 (rank : 873)	θ value	θ > 10 (rank : 1004)
Query Neighborhood Hits	905	Target Neighborhood Hits	155	Shared Neighborhood Hits	20
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

TMG1_HUMAN
NC score	0.070616 (rank : 874)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	905	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

MT1H_HUMAN
NC score	0.070372 (rank : 875)	θ value	θ > 10 (rank : 1020)
Query Neighborhood Hits	905	Target Neighborhood Hits	78	Shared Neighborhood Hits	52
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

KR131_HUMAN
NC score	0.070258 (rank : 876)	θ value	θ > 10 (rank : 993)
Query Neighborhood Hits	905	Target Neighborhood Hits	123	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

COCA1_MOUSE
NC score	0.070130 (rank : 877)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	905	Target Neighborhood Hits	467	Shared Neighborhood Hits	56
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

IDD_MOUSE
NC score	0.069938 (rank : 878)	θ value	θ > 10 (rank : 990)
Query Neighborhood Hits	905	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

TNR26_MOUSE
NC score	0.069424 (rank : 879)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	905	Target Neighborhood Hits	106	Shared Neighborhood Hits	66
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

GP116_HUMAN
NC score	0.069122 (rank : 880)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	905	Target Neighborhood Hits	167	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GPR64_MOUSE
NC score	0.069020 (rank : 881)	θ value	θ > 10 (rank : 976)
Query Neighborhood Hits	905	Target Neighborhood Hits	156	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

ODFP_MOUSE
NC score	0.068366 (rank : 882)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	905	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

GP114_HUMAN
NC score	0.068341 (rank : 883)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	905	Target Neighborhood Hits	75	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

SPR2I_MOUSE
NC score	0.068070 (rank : 884)	θ value	6.88961 (rank : 883)
Query Neighborhood Hits	905	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

GP179_HUMAN
NC score	0.067972 (rank : 885)	θ value	0.0113563 (rank : 580)
Query Neighborhood Hits	905	Target Neighborhood Hits	372	Shared Neighborhood Hits	55
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GPR64_HUMAN
NC score	0.067768 (rank : 886)	θ value	θ > 10 (rank : 975)
Query Neighborhood Hits	905	Target Neighborhood Hits	207	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

TNR22_MOUSE
NC score	0.067741 (rank : 887)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	905	Target Neighborhood Hits	97	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

GP125_HUMAN
NC score	0.067646 (rank : 888)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	905	Target Neighborhood Hits	327	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

WISP2_MOUSE
NC score	0.067512 (rank : 889)	θ value	4.03905 (rank : 825)
Query Neighborhood Hits	905	Target Neighborhood Hits	129	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

GP124_MOUSE
NC score	0.067357 (rank : 890)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	905	Target Neighborhood Hits	423	Shared Neighborhood Hits	43
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

COKA1_HUMAN
NC score	0.067150 (rank : 891)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	905	Target Neighborhood Hits	403	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

COCA1_HUMAN
NC score	0.066803 (rank : 892)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	905	Target Neighborhood Hits	458	Shared Neighborhood Hits	54
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

RSPO2_MOUSE
NC score	0.066659 (rank : 893)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	905	Target Neighborhood Hits	88	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

TNR11_MOUSE
NC score	0.066266 (rank : 894)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	905	Target Neighborhood Hits	121	Shared Neighborhood Hits	62
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

RSPO2_HUMAN
NC score	0.064967 (rank : 895)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	905	Target Neighborhood Hits	90	Shared Neighborhood Hits	52
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

CSPG4_MOUSE
NC score	0.064895 (rank : 896)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	905	Target Neighborhood Hits	105	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CSPG4_HUMAN
NC score	0.064545 (rank : 897)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	905	Target Neighborhood Hits	112	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

WISP1_MOUSE
NC score	0.064537 (rank : 898)	θ value	0.813845 (rank : 751)
Query Neighborhood Hits	905	Target Neighborhood Hits	123	Shared Neighborhood Hits	57
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

GP124_HUMAN
NC score	0.064527 (rank : 899)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	905	Target Neighborhood Hits	304	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

CSMD1_MOUSE
NC score	0.064385 (rank : 900)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	905	Target Neighborhood Hits	193	Shared Neighborhood Hits	84
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

MFRP_MOUSE
NC score	0.064280 (rank : 901)	θ value	θ > 10 (rank : 1016)
Query Neighborhood Hits	905	Target Neighborhood Hits	166	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

ENTK_MOUSE
NC score	0.064248 (rank : 902)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	905	Target Neighborhood Hits	338	Shared Neighborhood Hits	97
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

GPR97_MOUSE
NC score	0.064221 (rank : 903)	θ value	θ > 10 (rank : 978)
Query Neighborhood Hits	905	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

KR134_HUMAN
NC score	0.064163 (rank : 904)	θ value	θ > 10 (rank : 996)
Query Neighborhood Hits	905	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

TNR7_MOUSE
NC score	0.064043 (rank : 905)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	905	Target Neighborhood Hits	112	Shared Neighborhood Hits	56
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

GPR56_MOUSE
NC score	0.063994 (rank : 906)	θ value	θ > 10 (rank : 974)
Query Neighborhood Hits	905	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

CU081_HUMAN
NC score	0.063957 (rank : 907)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	905	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

NOV_MOUSE
NC score	0.063917 (rank : 908)	θ value	5.27518 (rank : 848)
Query Neighborhood Hits	905	Target Neighborhood Hits	130	Shared Neighborhood Hits	69
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

GPR56_HUMAN
NC score	0.063790 (rank : 909)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	905	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

TMG3_HUMAN
NC score	0.063599 (rank : 910)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	905	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

GP125_MOUSE
NC score	0.063535 (rank : 911)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	905	Target Neighborhood Hits	329	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

CSMD1_HUMAN
NC score	0.063475 (rank : 912)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	905	Target Neighborhood Hits	176	Shared Neighborhood Hits	74
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

TMG3_MOUSE
NC score	0.063231 (rank : 913)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	905	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

HPLN2_MOUSE
NC score	0.063068 (rank : 914)	θ value	θ > 10 (rank : 984)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

COEA1_MOUSE
NC score	0.063027 (rank : 915)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	905	Target Neighborhood Hits	402	Shared Neighborhood Hits	44
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

WISP1_HUMAN
NC score	0.062653 (rank : 916)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	905	Target Neighborhood Hits	121	Shared Neighborhood Hits	58
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

HPLN2_HUMAN
NC score	0.062141 (rank : 917)	θ value	θ > 10 (rank : 983)
Query Neighborhood Hits	905	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

CSMD3_HUMAN
NC score	0.062022 (rank : 918)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	905	Target Neighborhood Hits	199	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

MCSP_HUMAN
NC score	0.061901 (rank : 919)	θ value	θ > 10 (rank : 1012)
Query Neighborhood Hits	905	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

HPLN3_MOUSE
NC score	0.061770 (rank : 920)	θ value	θ > 10 (rank : 986)
Query Neighborhood Hits	905	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

GP110_HUMAN
NC score	0.061402 (rank : 921)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	905	Target Neighborhood Hits	87	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP110_MOUSE
NC score	0.061243 (rank : 922)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	905	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

TNR3_MOUSE
NC score	0.060737 (rank : 923)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	905	Target Neighborhood Hits	113	Shared Neighborhood Hits	61
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

COEA1_HUMAN
NC score	0.060517 (rank : 924)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	905	Target Neighborhood Hits	427	Shared Neighborhood Hits	48
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

HPLN3_HUMAN
NC score	0.060416 (rank : 925)	θ value	θ > 10 (rank : 985)
Query Neighborhood Hits	905	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

NRP2_HUMAN
NC score	0.060211 (rank : 926)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

CRDL1_MOUSE
NC score	0.060175 (rank : 927)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	905	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

HPLN4_MOUSE
NC score	0.059789 (rank : 928)	θ value	θ > 10 (rank : 988)
Query Neighborhood Hits	905	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

ENTK_HUMAN
NC score	0.059734 (rank : 929)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	905	Target Neighborhood Hits	310	Shared Neighborhood Hits	91
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

GP115_MOUSE
NC score	0.059554 (rank : 930)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	905	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

HPLN1_MOUSE
NC score	0.059410 (rank : 931)	θ value	θ > 10 (rank : 982)
Query Neighborhood Hits	905	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN1_HUMAN
NC score	0.059382 (rank : 932)	θ value	θ > 10 (rank : 981)
Query Neighborhood Hits	905	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN4_HUMAN
NC score	0.059115 (rank : 933)	θ value	θ > 10 (rank : 987)
Query Neighborhood Hits	905	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

CRDL1_HUMAN
NC score	0.059088 (rank : 934)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	905	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

MT1L_HUMAN
NC score	0.059074 (rank : 935)	θ value	θ > 10 (rank : 1021)
Query Neighborhood Hits	905	Target Neighborhood Hits	73	Shared Neighborhood Hits	48
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

KR133_HUMAN
NC score	0.059046 (rank : 936)	θ value	θ > 10 (rank : 995)
Query Neighborhood Hits	905	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

TNR6_MOUSE
NC score	0.058683 (rank : 937)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	905	Target Neighborhood Hits	99	Shared Neighborhood Hits	54
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

PROP_HUMAN
NC score	0.058587 (rank : 938)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	905	Target Neighborhood Hits	126	Shared Neighborhood Hits	46
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

SPR2E_MOUSE
NC score	0.058586 (rank : 939)	θ value	6.88961 (rank : 882)
Query Neighborhood Hits	905	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

GPR97_HUMAN
NC score	0.058439 (rank : 940)	θ value	θ > 10 (rank : 977)
Query Neighborhood Hits	905	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

TNR5_HUMAN
NC score	0.058185 (rank : 941)	θ value	1.38821 (rank : 774)
Query Neighborhood Hits	905	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR6B_HUMAN
NC score	0.058019 (rank : 942)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	905	Target Neighborhood Hits	103	Shared Neighborhood Hits	50
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

GP115_HUMAN
NC score	0.057835 (rank : 943)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	905	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

NRP2_MOUSE
NC score	0.057738 (rank : 944)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	905	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

KR132_HUMAN
NC score	0.056919 (rank : 945)	θ value	θ > 10 (rank : 994)
Query Neighborhood Hits	905	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

EPHB4_HUMAN
NC score	0.056841 (rank : 946)	θ value	0.00228821 (rank : 532)
Query Neighborhood Hits	905	Target Neighborhood Hits	1056	Shared Neighborhood Hits	169
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

ATS9_HUMAN
NC score	0.056734 (rank : 947)	θ value	2.36792 (rank : 787)
Query Neighborhood Hits	905	Target Neighborhood Hits	219	Shared Neighborhood Hits	120
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

NETO1_HUMAN
NC score	0.056419 (rank : 948)	θ value	θ > 10 (rank : 1027)
Query Neighborhood Hits	905	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

CSMD2_HUMAN
NC score	0.056106 (rank : 949)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	905	Target Neighborhood Hits	188	Shared Neighborhood Hits	70
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

NETO1_MOUSE
NC score	0.056049 (rank : 950)	θ value	θ > 10 (rank : 1028)
Query Neighborhood Hits	905	Target Neighborhood Hits	109	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

GP123_HUMAN
NC score	0.056046 (rank : 951)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

NRP1_HUMAN
NC score	0.055958 (rank : 952)	θ value	θ > 10 (rank : 1031)
Query Neighborhood Hits	905	Target Neighborhood Hits	119	Shared Neighborhood Hits	47
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

TRPC6_HUMAN
NC score	0.055886 (rank : 953)	θ value	1.06291 (rank : 763)
Query Neighborhood Hits	905	Target Neighborhood Hits	171	Shared Neighborhood Hits	100
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

GPR98_HUMAN
NC score	0.055649 (rank : 954)	θ value	θ > 10 (rank : 979)
Query Neighborhood Hits	905	Target Neighborhood Hits	202	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GP111_HUMAN
NC score	0.055498 (rank : 955)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	905	Target Neighborhood Hits	77	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

NRP1_MOUSE
NC score	0.055435 (rank : 956)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	905	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

PGCA_MOUSE
NC score	0.055256 (rank : 957)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	905	Target Neighborhood Hits	643	Shared Neighborhood Hits	57
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

SPIT1_HUMAN
NC score	0.054964 (rank : 958)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	905	Target Neighborhood Hits	100	Shared Neighborhood Hits	48
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

MT1E_HUMAN
NC score	0.054728 (rank : 959)	θ value	θ > 10 (rank : 1019)
Query Neighborhood Hits	905	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

TMG2_HUMAN
NC score	0.054617 (rank : 960)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	905	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O14669	Gene names	PRRG2, PRGP2, TMG2
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2).

TNR1B_HUMAN
NC score	0.054528 (rank : 961)	θ value	0.0961366 (rank : 654)
Query Neighborhood Hits	905	Target Neighborhood Hits	127	Shared Neighborhood Hits	56
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

CO7A1_HUMAN
NC score	0.054438 (rank : 962)	θ value	6.88961 (rank : 861)
Query Neighborhood Hits	905	Target Neighborhood Hits	807	Shared Neighborhood Hits	89
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

NETO2_HUMAN
NC score	0.054171 (rank : 963)	θ value	θ > 10 (rank : 1029)
Query Neighborhood Hits	905	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
NC score	0.054137 (rank : 964)	θ value	θ > 10 (rank : 1030)
Query Neighborhood Hits	905	Target Neighborhood Hits	113	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

GPR98_MOUSE
NC score	0.053794 (rank : 965)	θ value	θ > 10 (rank : 980)
Query Neighborhood Hits	905	Target Neighborhood Hits	206	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

TMG4_HUMAN
NC score	0.053786 (rank : 966)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	905	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

NRX1B_HUMAN
NC score	0.053369 (rank : 967)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	905	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

GLU2B_HUMAN
NC score	0.053288 (rank : 968)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	905	Target Neighborhood Hits	377	Shared Neighborhood Hits	49
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

TMG2_MOUSE
NC score	0.052935 (rank : 969)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	905	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R182, Q9EQI2	Gene names	Prrg2, N4wbp1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2) (NEDD4 WW domain-binding protein 1).

CFAB_MOUSE
NC score	0.052826 (rank : 970)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	905	Target Neighborhood Hits	262	Shared Neighborhood Hits	67
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

ADEC1_MOUSE
NC score	0.052809 (rank : 971)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	905	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

LRP11_MOUSE
NC score	0.052761 (rank : 972)	θ value	θ > 10 (rank : 1008)
Query Neighborhood Hits	905	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

SPIT1_MOUSE
NC score	0.052539 (rank : 973)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	905	Target Neighborhood Hits	96	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

KREM1_MOUSE
NC score	0.052404 (rank : 974)	θ value	θ > 10 (rank : 998)
Query Neighborhood Hits	905	Target Neighborhood Hits	92	Shared Neighborhood Hits	39
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

TNR6_HUMAN
NC score	0.052331 (rank : 975)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	905	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

DCBD1_HUMAN
NC score	0.052315 (rank : 976)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	905	Target Neighborhood Hits	110	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

KREM2_HUMAN
NC score	0.052297 (rank : 977)	θ value	θ > 10 (rank : 999)
Query Neighborhood Hits	905	Target Neighborhood Hits	93	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

TNR1A_HUMAN
NC score	0.052198 (rank : 978)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	905	Target Neighborhood Hits	121	Shared Neighborhood Hits	50
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

MFAP4_MOUSE
NC score	0.052148 (rank : 979)	θ value	θ > 10 (rank : 1014)
Query Neighborhood Hits	905	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_HUMAN
NC score	0.052082 (rank : 980)	θ value	θ > 10 (rank : 1013)
Query Neighborhood Hits	905	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

KR121_HUMAN
NC score	0.051884 (rank : 981)	θ value	θ > 10 (rank : 992)
Query Neighborhood Hits	905	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	P59990	Gene names	KRTAP12-1, KAP12.1, KRTAP12.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-1 (Keratin-associated protein 12.1) (High sulfur keratin-associated protein 12.1).

TNR3_HUMAN
NC score	0.051747 (rank : 982)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	905	Target Neighborhood Hits	145	Shared Neighborhood Hits	58
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR19_HUMAN
NC score	0.051539 (rank : 983)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	905	Target Neighborhood Hits	89	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

SPR2F_MOUSE
NC score	0.051381 (rank : 984)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	905	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

TNR18_HUMAN
NC score	0.051150 (rank : 985)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	905	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

LRP11_HUMAN
NC score	0.050952 (rank : 986)	θ value	θ > 10 (rank : 1007)
Query Neighborhood Hits	905	Target Neighborhood Hits	82	Shared Neighborhood Hits	38
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

RSPO1_HUMAN
NC score	0.050648 (rank : 987)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	905	Target Neighborhood Hits	101	Shared Neighborhood Hits	52
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

FCN3_HUMAN
NC score	0.050610 (rank : 988)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	905	Target Neighborhood Hits	125	Shared Neighborhood Hits	19
SwissProt Accessions	O75636, Q6IBJ5, Q8WW86	Gene names	FCN3, HAKA1
Domain Architecture
Description	Ficolin-3 precursor (Collagen/fibrinogen domain-containing protein 3) (Collagen/fibrinogen domain-containing lectin 3 p35) (Hakata antigen).

ADEC1_HUMAN
NC score	0.050520 (rank : 989)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	905	Target Neighborhood Hits	80	Shared Neighborhood Hits	40
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

TNR19_MOUSE
NC score	0.050511 (rank : 990)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	905	Target Neighborhood Hits	100	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

SPR2E_HUMAN
NC score	0.050100 (rank : 991)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	905	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

TNR1A_MOUSE
NC score	0.050063 (rank : 992)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	905	Target Neighborhood Hits	131	Shared Neighborhood Hits	56
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

FIBA_HUMAN
NC score	0.049149 (rank : 993)	θ value	1.38821 (rank : 768)
Query Neighborhood Hits	905	Target Neighborhood Hits	132	Shared Neighborhood Hits	16
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

HYAL3_MOUSE
NC score	0.048866 (rank : 994)	θ value	3.0926 (rank : 806)
Query Neighborhood Hits	905	Target Neighborhood Hits	44	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

SPY4_MOUSE
NC score	0.048649 (rank : 995)	θ value	0.813845 (rank : 750)
Query Neighborhood Hits	905	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

SPY1_HUMAN
NC score	0.048555 (rank : 996)	θ value	4.03905 (rank : 823)
Query Neighborhood Hits	905	Target Neighborhood Hits	64	Shared Neighborhood Hits	49
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

LORI_HUMAN
NC score	0.047626 (rank : 997)	θ value	8.99809 (rank : 896)
Query Neighborhood Hits	905	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	P23490	Gene names	LOR, LRN
Domain Architecture	No domain graphic available
Description	Loricrin.

LYPD1_MOUSE
NC score	0.046920 (rank : 998)	θ value	1.06291 (rank : 759)
Query Neighborhood Hits	905	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BLC3, Q3V2X5, Q3V447, Q9JJ96	Gene names	Lypd1, Lypdc1
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 1 precursor.

SPY1_MOUSE
NC score	0.046913 (rank : 999)	θ value	4.03905 (rank : 824)
Query Neighborhood Hits	905	Target Neighborhood Hits	57	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

INSRR_MOUSE
NC score	0.046277 (rank : 1000)	θ value	5.27518 (rank : 840)
Query Neighborhood Hits	905	Target Neighborhood Hits	961	Shared Neighborhood Hits	142
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

LYPD1_HUMAN
NC score	0.045675 (rank : 1001)	θ value	1.38821 (rank : 769)
Query Neighborhood Hits	905	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N2G4, Q96AC2	Gene names	LYPD1, LYPDC1
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 1 precursor.

INSRR_HUMAN
NC score	0.045490 (rank : 1002)	θ value	6.88961 (rank : 874)
Query Neighborhood Hits	905	Target Neighborhood Hits	950	Shared Neighborhood Hits	134
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

TR10B_MOUSE
NC score	0.045224 (rank : 1003)	θ value	5.27518 (rank : 851)
Query Neighborhood Hits	905	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

IMPG1_HUMAN
NC score	0.044241 (rank : 1004)	θ value	1.81305 (rank : 778)
Query Neighborhood Hits	905	Target Neighborhood Hits	75	Shared Neighborhood Hits	26
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

TYRP1_MOUSE
NC score	0.043887 (rank : 1005)	θ value	0.279714 (rank : 703)
Query Neighborhood Hits	905	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	P07147	Gene names	Tyrp1, Tyrp-1
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Brown locus protein).

MLL3_MOUSE
NC score	0.042072 (rank : 1006)	θ value	1.38821 (rank : 770)
Query Neighborhood Hits	905	Target Neighborhood Hits	1399	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TNR1B_MOUSE
NC score	0.040494 (rank : 1007)	θ value	2.36792 (rank : 791)
Query Neighborhood Hits	905	Target Neighborhood Hits	123	Shared Neighborhood Hits	48
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TYRP1_HUMAN
NC score	0.040403 (rank : 1008)	θ value	3.0926 (rank : 814)
Query Neighborhood Hits	905	Target Neighborhood Hits	40	Shared Neighborhood Hits	32
SwissProt Accessions	P17643, P78468, P78469, Q13721, Q15679	Gene names	TYRP1, CAS2, TYRP, TYRRP
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75).

EPHB4_MOUSE
NC score	0.039233 (rank : 1009)	θ value	0.0193708 (rank : 594)
Query Neighborhood Hits	905	Target Neighborhood Hits	1013	Shared Neighborhood Hits	139
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

MLL3_HUMAN
NC score	0.039176 (rank : 1010)	θ value	3.0926 (rank : 808)
Query Neighborhood Hits	905	Target Neighborhood Hits	1644	Shared Neighborhood Hits	128
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SPY3_HUMAN
NC score	0.038107 (rank : 1011)	θ value	0.813845 (rank : 749)
Query Neighborhood Hits	905	Target Neighborhood Hits	48	Shared Neighborhood Hits	31
SwissProt Accessions	O43610	Gene names	SPRY3
Domain Architecture
Description	Sprouty homolog 3 (Spry-3).

EPHA1_HUMAN
NC score	0.037179 (rank : 1012)	θ value	0.163984 (rank : 667)
Query Neighborhood Hits	905	Target Neighborhood Hits	997	Shared Neighborhood Hits	134
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

ATL2_HUMAN
NC score	0.036606 (rank : 1013)	θ value	5.27518 (rank : 831)
Query Neighborhood Hits	905	Target Neighborhood Hits	125	Shared Neighborhood Hits	49
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

SPY4_HUMAN
NC score	0.034859 (rank : 1014)	θ value	0.47712 (rank : 729)
Query Neighborhood Hits	905	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q9C004, Q6QIX2, Q9C003	Gene names	SPRY4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

SPR2K_MOUSE
NC score	0.034776 (rank : 1015)	θ value	5.27518 (rank : 850)
Query Neighborhood Hits	905	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	O70562	Gene names	Sprr2k
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2K.

EPHB6_HUMAN
NC score	0.034231 (rank : 1016)	θ value	8.99809 (rank : 891)
Query Neighborhood Hits	905	Target Neighborhood Hits	912	Shared Neighborhood Hits	113
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

IGF1R_MOUSE
NC score	0.033218 (rank : 1017)	θ value	0.125558 (rank : 660)
Query Neighborhood Hits	905	Target Neighborhood Hits	973	Shared Neighborhood Hits	143
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

CFAH_MOUSE
NC score	0.032942 (rank : 1018)	θ value	6.88961 (rank : 859)
Query Neighborhood Hits	905	Target Neighborhood Hits	112	Shared Neighborhood Hits	41
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

INSR_HUMAN
NC score	0.032912 (rank : 1019)	θ value	0.365318 (rank : 710)
Query Neighborhood Hits	905	Target Neighborhood Hits	963	Shared Neighborhood Hits	131
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

SDK1_HUMAN
NC score	0.032807 (rank : 1020)	θ value	6.88961 (rank : 881)
Query Neighborhood Hits	905	Target Neighborhood Hits	511	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

ATL2_MOUSE
NC score	0.031297 (rank : 1021)	θ value	1.06291 (rank : 755)
Query Neighborhood Hits	905	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

PRR13_MOUSE
NC score	0.031139 (rank : 1022)	θ value	1.06291 (rank : 760)
Query Neighborhood Hits	905	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

ENPP2_MOUSE
NC score	0.030671 (rank : 1023)	θ value	8.99809 (rank : 890)
Query Neighborhood Hits	905	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ERBB3_HUMAN
NC score	0.029874 (rank : 1024)	θ value	0.0431538 (rank : 623)
Query Neighborhood Hits	905	Target Neighborhood Hits	918	Shared Neighborhood Hits	129
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

IGF1R_HUMAN
NC score	0.028885 (rank : 1025)	θ value	0.21417 (rank : 679)
Query Neighborhood Hits	905	Target Neighborhood Hits	977	Shared Neighborhood Hits	142
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

NCOA6_MOUSE
NC score	0.028699 (rank : 1026)	θ value	3.0926 (rank : 811)
Query Neighborhood Hits	905	Target Neighborhood Hits	1076	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ERBB4_HUMAN
NC score	0.027916 (rank : 1027)	θ value	0.0113563 (rank : 579)
Query Neighborhood Hits	905	Target Neighborhood Hits	910	Shared Neighborhood Hits	103
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

ERBB3_MOUSE
NC score	0.026483 (rank : 1028)	θ value	0.365318 (rank : 708)
Query Neighborhood Hits	905	Target Neighborhood Hits	898	Shared Neighborhood Hits	109
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

EPHB2_HUMAN
NC score	0.026475 (rank : 1029)	θ value	0.365318 (rank : 706)
Query Neighborhood Hits	905	Target Neighborhood Hits	983	Shared Neighborhood Hits	98
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

MMRN2_HUMAN
NC score	0.026358 (rank : 1030)	θ value	4.03905 (rank : 820)
Query Neighborhood Hits	905	Target Neighborhood Hits	400	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

EPHB2_MOUSE
NC score	0.026189 (rank : 1031)	θ value	0.365318 (rank : 707)
Query Neighborhood Hits	905	Target Neighborhood Hits	982	Shared Neighborhood Hits	98
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB1_HUMAN
NC score	0.025437 (rank : 1032)	θ value	0.0961366 (rank : 649)
Query Neighborhood Hits	905	Target Neighborhood Hits	988	Shared Neighborhood Hits	110
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

ENPP2_HUMAN
NC score	0.024685 (rank : 1033)	θ value	5.27518 (rank : 836)
Query Neighborhood Hits	905	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

MGAT3_HUMAN
NC score	0.024355 (rank : 1034)	θ value	8.99809 (rank : 897)
Query Neighborhood Hits	905	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	Q09327, Q6IC49, Q9UH32	Gene names	MGAT3, GGNT3
Domain Architecture
Description	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase III) (N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III).

MBD6_HUMAN
NC score	0.024211 (rank : 1035)	θ value	2.36792 (rank : 790)
Query Neighborhood Hits	905	Target Neighborhood Hits	349	Shared Neighborhood Hits	33
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

COGA1_HUMAN
NC score	0.024088 (rank : 1036)	θ value	0.21417 (rank : 678)
Query Neighborhood Hits	905	Target Neighborhood Hits	345	Shared Neighborhood Hits	46
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

MPRI_MOUSE
NC score	0.023943 (rank : 1037)	θ value	0.163984 (rank : 669)
Query Neighborhood Hits	905	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q07113, Q61822, Q6LED1	Gene names	Igf2r
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300).

HYAL2_HUMAN
NC score	0.023880 (rank : 1038)	θ value	0.62314 (rank : 737)
Query Neighborhood Hits	905	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	Q12891, O15177, Q9BW29	Gene names	HYAL2, LUCA2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

MGAT3_MOUSE
NC score	0.022431 (rank : 1039)	θ value	8.99809 (rank : 898)
Query Neighborhood Hits	905	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	Q10470, P70386	Gene names	Mgat3
Domain Architecture
Description	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.144) (N-glycosyl-oligosaccharide-glycoprotein N- acetylglucosaminyltransferase III) (N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III).

PRR13_HUMAN
NC score	0.022070 (rank : 1040)	θ value	8.99809 (rank : 902)
Query Neighborhood Hits	905	Target Neighborhood Hits	105	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

TACC3_HUMAN
NC score	0.020463 (rank : 1041)	θ value	1.06291 (rank : 761)
Query Neighborhood Hits	905	Target Neighborhood Hits	779	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

MPRI_HUMAN
NC score	0.020037 (rank : 1042)	θ value	1.38821 (rank : 771)
Query Neighborhood Hits	905	Target Neighborhood Hits	67	Shared Neighborhood Hits	9
SwissProt Accessions	P11717, Q7Z7G9, Q96PT5	Gene names	IGF2R, MPRI
Domain Architecture
Description	Cation-independent mannose-6-phosphate receptor precursor (CI Man-6-P receptor) (CI-MPR) (M6PR) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (300 kDa mannose 6-phosphate receptor) (MPR 300) (MPR300) (CD222 antigen).

IER5_MOUSE
NC score	0.019656 (rank : 1043)	θ value	1.06291 (rank : 757)
Query Neighborhood Hits	905	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

TYPH_HUMAN
NC score	0.018467 (rank : 1044)	θ value	0.0961366 (rank : 655)
Query Neighborhood Hits	905	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P19971, Q13390, Q8WVB7	Gene names	ECGF1
Domain Architecture
Description	Thymidine phosphorylase precursor (EC 2.4.2.4) (TdRPase) (TP) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (Gliostatin).

SPR1B_MOUSE
NC score	0.014844 (rank : 1045)	θ value	1.81305 (rank : 783)
Query Neighborhood Hits	905	Target Neighborhood Hits	395	Shared Neighborhood Hits	43
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

FSTL4_HUMAN
NC score	0.014430 (rank : 1046)	θ value	6.88961 (rank : 871)
Query Neighborhood Hits	905	Target Neighborhood Hits	344	Shared Neighborhood Hits	28
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

U6126_HUMAN
NC score	0.014328 (rank : 1047)	θ value	1.81305 (rank : 784)
Query Neighborhood Hits	905	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UXV3	Gene names	ames=UNQ6126/PRO20091
Domain Architecture	No domain graphic available
Description	Protein UNQ6126/PRO20091 precursor.

SPR1A_MOUSE
NC score	0.014122 (rank : 1048)	θ value	0.813845 (rank : 748)
Query Neighborhood Hits	905	Target Neighborhood Hits	343	Shared Neighborhood Hits	37
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

CO6A1_HUMAN
NC score	0.014082 (rank : 1049)	θ value	4.03905 (rank : 816)
Query Neighborhood Hits	905	Target Neighborhood Hits	264	Shared Neighborhood Hits	25
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

SYN1_HUMAN
NC score	0.013788 (rank : 1050)	θ value	6.88961 (rank : 884)
Query Neighborhood Hits	905	Target Neighborhood Hits	419	Shared Neighborhood Hits	37
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

CTG1B_HUMAN
NC score	0.013281 (rank : 1051)	θ value	0.62314 (rank : 735)
Query Neighborhood Hits	905	Target Neighborhood Hits	61	Shared Neighborhood Hits	10
SwissProt Accessions	P78358, Q7LBY4	Gene names	CTAG1B, CTAG, CTAG1, ESO1, LAGE2
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen 1B (L antigen family member 2) (LAGE-2 protein) (Autoimmunogenic cancer/testis antigen NY-ESO-1).

TYPH_MOUSE
NC score	0.013024 (rank : 1052)	θ value	2.36792 (rank : 792)
Query Neighborhood Hits	905	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q99N42	Gene names	Ecgf1
Domain Architecture
Description	Thymidine phosphorylase (EC 2.4.2.4) (TdRPase) (TP).

GFRA3_MOUSE
NC score	0.011870 (rank : 1053)	θ value	0.47712 (rank : 722)
Query Neighborhood Hits	905	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

AKAP2_HUMAN
NC score	0.011783 (rank : 1054)	θ value	0.813845 (rank : 740)
Query Neighborhood Hits	905	Target Neighborhood Hits	507	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

ICAM5_MOUSE
NC score	0.011724 (rank : 1055)	θ value	4.03905 (rank : 817)
Query Neighborhood Hits	905	Target Neighborhood Hits	308	Shared Neighborhood Hits	12
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

HYAL1_HUMAN
NC score	0.011557 (rank : 1056)	θ value	8.99809 (rank : 893)
Query Neighborhood Hits	905	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q12794, Q6FH23, Q6PIZ6, Q7KYU2, Q7LE34, Q8NFK5, Q8NFK6, Q8NFK7, Q8NFK8, Q8NFK9, Q93013, Q9UKD5, Q9UNI8	Gene names	HYAL1, LUCA1
Domain Architecture	No domain graphic available
Description	Hyaluronidase-1 precursor (EC 3.2.1.35) (Hyal-1) (Hyaluronoglucosaminidase-1) (LUCA-1).

MNT_HUMAN
NC score	0.011412 (rank : 1057)	θ value	8.99809 (rank : 899)
Query Neighborhood Hits	905	Target Neighborhood Hits	496	Shared Neighborhood Hits	32
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

AMER1_MOUSE
NC score	0.011387 (rank : 1058)	θ value	0.62314 (rank : 731)
Query Neighborhood Hits	905	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHT5	Gene names	Ammecr1
Domain Architecture
Description	AMME syndrome candidate gene 1 protein homolog.

HYAL1_MOUSE
NC score	0.010525 (rank : 1059)	θ value	8.99809 (rank : 894)
Query Neighborhood Hits	905	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZJ9, O70229, Q8CE62, Q8QZX3, Q8VBW7, Q8VDK0	Gene names	Hyal1
Domain Architecture	No domain graphic available
Description	Hyaluronidase-1 precursor (EC 3.2.1.35) (Hyal-1) (Hyaluronoglucosaminidase-1).

RING1_MOUSE
NC score	0.010315 (rank : 1060)	θ value	0.163984 (rank : 671)
Query Neighborhood Hits	905	Target Neighborhood Hits	220	Shared Neighborhood Hits	16
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

BAMBI_MOUSE
NC score	0.009378 (rank : 1061)	θ value	3.0926 (rank : 798)
Query Neighborhood Hits	905	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D0L6, Q3TP85, Q91XS6	Gene names	Bambi, Nma
Domain Architecture	No domain graphic available
Description	BMP and activin membrane-bound inhibitor homolog precursor (Putative transmembrane protein NMA).

DGKQ_HUMAN
NC score	0.009328 (rank : 1062)	θ value	2.36792 (rank : 788)
Query Neighborhood Hits	905	Target Neighborhood Hits	131	Shared Neighborhood Hits	16
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

COBA1_MOUSE
NC score	0.008958 (rank : 1063)	θ value	6.88961 (rank : 864)
Query Neighborhood Hits	905	Target Neighborhood Hits	487	Shared Neighborhood Hits	40
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

LTK_HUMAN
NC score	0.008957 (rank : 1064)	θ value	4.03905 (rank : 819)
Query Neighborhood Hits	905	Target Neighborhood Hits	774	Shared Neighborhood Hits	39
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
NC score	0.008624 (rank : 1065)	θ value	3.0926 (rank : 807)
Query Neighborhood Hits	905	Target Neighborhood Hits	770	Shared Neighborhood Hits	39
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

ARMX2_HUMAN
NC score	0.008436 (rank : 1066)	θ value	0.21417 (rank : 675)
Query Neighborhood Hits	905	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

CU024_HUMAN
NC score	0.008311 (rank : 1067)	θ value	6.88961 (rank : 868)
Query Neighborhood Hits	905	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q6XXX2	Gene names	C21orf24
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf24.

RING1_HUMAN
NC score	0.007720 (rank : 1068)	θ value	0.813845 (rank : 747)
Query Neighborhood Hits	905	Target Neighborhood Hits	219	Shared Neighborhood Hits	16
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

COBA1_HUMAN
NC score	0.007428 (rank : 1069)	θ value	6.88961 (rank : 863)
Query Neighborhood Hits	905	Target Neighborhood Hits	491	Shared Neighborhood Hits	38
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

IRS2_HUMAN
NC score	0.006912 (rank : 1070)	θ value	8.99809 (rank : 895)
Query Neighborhood Hits	905	Target Neighborhood Hits	262	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

APXL_HUMAN
NC score	0.006674 (rank : 1071)	θ value	0.125558 (rank : 657)
Query Neighborhood Hits	905	Target Neighborhood Hits	553	Shared Neighborhood Hits	19
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

HAIR_HUMAN
NC score	0.006658 (rank : 1072)	θ value	6.88961 (rank : 872)
Query Neighborhood Hits	905	Target Neighborhood Hits	172	Shared Neighborhood Hits	19
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

HEM6_HUMAN
NC score	0.004053 (rank : 1073)	θ value	5.27518 (rank : 839)
Query Neighborhood Hits	905	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P36551, Q14060, Q8IZ45, Q96AF3	Gene names	CPOX, CPO, CPX
Domain Architecture
Description	Coproporphyrinogen III oxidase, mitochondrial precursor (EC 1.3.3.3) (Coproporphyrinogenase) (Coprogen oxidase) (COX).

HGS_MOUSE
NC score	0.003663 (rank : 1074)	θ value	8.99809 (rank : 892)
Query Neighborhood Hits	905	Target Neighborhood Hits	589	Shared Neighborhood Hits	21
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

COIA1_MOUSE
NC score	0.003508 (rank : 1075)	θ value	5.27518 (rank : 834)
Query Neighborhood Hits	905	Target Neighborhood Hits	481	Shared Neighborhood Hits	37
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

COHA1_MOUSE
NC score	0.002938 (rank : 1076)	θ value	6.88961 (rank : 865)
Query Neighborhood Hits	905	Target Neighborhood Hits	414	Shared Neighborhood Hits	28
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

MARH2_HUMAN
NC score	0.002355 (rank : 1077)	θ value	5.27518 (rank : 844)
Query Neighborhood Hits	905	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P0N8, Q8N5A3, Q96B78	Gene names	MARCH2, RNF172
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 2 (Membrane-associated RING-CH protein II) (MARCH-II) (RING finger protein 172).

MEFV_MOUSE
NC score	0.002209 (rank : 1078)	θ value	6.88961 (rank : 878)
Query Neighborhood Hits	905	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

WNT9A_HUMAN
NC score	0.001694 (rank : 1079)	θ value	2.36792 (rank : 793)
Query Neighborhood Hits	905	Target Neighborhood Hits	52	Shared Neighborhood Hits	9
SwissProt Accessions	O14904, Q5VWU0, Q96S50	Gene names	WNT9A, WNT14
Domain Architecture
Description	Protein Wnt-9a precursor (Wnt-14).

KCNH4_HUMAN
NC score	0.001172 (rank : 1080)	θ value	0.813845 (rank : 744)
Query Neighborhood Hits	905	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

SPEG_HUMAN
NC score	0.000788 (rank : 1081)	θ value	4.03905 (rank : 822)
Query Neighborhood Hits	905	Target Neighborhood Hits	1762	Shared Neighborhood Hits	85
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CO4A6_HUMAN
NC score	0.000687 (rank : 1082)	θ value	3.0926 (rank : 801)
Query Neighborhood Hits	905	Target Neighborhood Hits	318	Shared Neighborhood Hits	24
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

WNT9A_MOUSE
NC score	0.000618 (rank : 1083)	θ value	4.03905 (rank : 826)
Query Neighborhood Hits	905	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R5M2	Gene names	Wnt9a, Wnt14
Domain Architecture
Description	Protein Wnt-9a precursor (Wnt-14).

CO9A3_HUMAN
NC score	-0.000428 (rank : 1084)	θ value	0.813845 (rank : 742)
Query Neighborhood Hits	905	Target Neighborhood Hits	361	Shared Neighborhood Hits	22
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

UBP38_HUMAN
NC score	-0.001651 (rank : 1085)	θ value	6.88961 (rank : 886)
Query Neighborhood Hits	905	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

FOXN1_HUMAN
NC score	-0.002469 (rank : 1086)	θ value	3.0926 (rank : 804)
Query Neighborhood Hits	905	Target Neighborhood Hits	377	Shared Neighborhood Hits	23
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

UBP51_HUMAN
NC score	-0.002719 (rank : 1087)	θ value	5.27518 (rank : 853)
Query Neighborhood Hits	905	Target Neighborhood Hits	162	Shared Neighborhood Hits	13
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

KRHB5_HUMAN
NC score	-0.004185 (rank : 1088)	θ value	4.03905 (rank : 818)
Query Neighborhood Hits	905	Target Neighborhood Hits	321	Shared Neighborhood Hits	15
SwissProt Accessions	P78386, Q9NSB1	Gene names	KRTHB5
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

TRI65_HUMAN
NC score	-0.005170 (rank : 1089)	θ value	6.88961 (rank : 885)
Query Neighborhood Hits	905	Target Neighborhood Hits	330	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

N2DL3_HUMAN
NC score	-0.005315 (rank : 1090)	θ value	5.27518 (rank : 847)
Query Neighborhood Hits	905	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZM4, Q8IZX5, Q8TE75	Gene names	ULBP3, N2DL3, RAET1N
Domain Architecture
Description	NKG2D ligand 3 precursor (NKG2D ligand 3) (NKG2DL3) (N2DL-3) (ALCAN- gamma) (Retinoic acid early transcript 1N).

PO4F2_MOUSE
NC score	-0.007381 (rank : 1091)	θ value	6.88961 (rank : 879)
Query Neighborhood Hits	905	Target Neighborhood Hits	312	Shared Neighborhood Hits	3
SwissProt Accessions	Q63934, Q63954	Gene names	Pou4f2, Brn3b
Domain Architecture
Description	POU domain, class 4, transcription factor 2 (Brain-specific homeobox/POU domain protein 3B) (Brn-3B) (Brn-3.2).

EDNRB_MOUSE
NC score	-0.016410 (rank : 1092)	θ value	6.88961 (rank : 869)
Query Neighborhood Hits	905	Target Neighborhood Hits	587	Shared Neighborhood Hits	2
SwissProt Accessions	P48302, Q542M3	Gene names	Ednrb
Domain Architecture
Description	Endothelin B receptor precursor (ET-B) (Endothelin receptor Non- selective type).

ZN446_HUMAN
NC score	-0.018038 (rank : 1093)	θ value	4.03905 (rank : 827)
Query Neighborhood Hits	905	Target Neighborhood Hits	721	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NWS9	Gene names	ZNF446
Domain Architecture	No domain graphic available
Description	Zinc finger protein 446.

BC11A_MOUSE
NC score	-0.018666 (rank : 1094)	θ value	3.0926 (rank : 800)
Query Neighborhood Hits	905	Target Neighborhood Hits	732	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYE3, Q80T89, Q8BLC7, Q8BLR4, Q8BWX3, Q921V4, Q9D0V2, Q9JIT4, Q9JLK8, Q9JLK9	Gene names	Bcl11a, Ctip1, Evi9, Kiaa1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).

BC11A_HUMAN
NC score	-0.019621 (rank : 1095)	θ value	3.0926 (rank : 799)
Query Neighborhood Hits	905	Target Neighborhood Hits	745	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H165, Q86W14, Q8WU92, Q96JL6, Q9H163, Q9H164, Q9H3G9, Q9NWA7	Gene names	BCL11A, CTIP1, EVI9, KIAA1809
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11A (B-cell CLL/lymphoma 11A) (COUP-TF- interacting protein 1) (Ecotropic viral integration site 9 protein) (EVI-9).