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Network neighborhood for query Sequence : DDFL1_HUMAN

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DDFL1_HUMAN
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DDEF1_MOUSE
θ value	0 (rank : 1)	NC score	0.878283 (rank : 5)
Query Neighborhood Hits	353	Target Neighborhood Hits	592	Shared Neighborhood Hits	222
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	0 (rank : 2)	NC score	0.899353 (rank : 3)
Query Neighborhood Hits	353	Target Neighborhood Hits	599	Shared Neighborhood Hits	263
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	0 (rank : 3)	NC score	0.893967 (rank : 4)
Query Neighborhood Hits	353	Target Neighborhood Hits	625	Shared Neighborhood Hits	259
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	353	Target Neighborhood Hits	353	Shared Neighborhood Hits	353
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
θ value	0 (rank : 5)	NC score	0.971896 (rank : 2)
Query Neighborhood Hits	353	Target Neighborhood Hits	324	Shared Neighborhood Hits	261
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

CENB5_HUMAN
θ value	1.41672e-45 (rank : 6)	NC score	0.806429 (rank : 6)
Query Neighborhood Hits	353	Target Neighborhood Hits	395	Shared Neighborhood Hits	264
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB2_HUMAN
θ value	2.67181e-44 (rank : 7)	NC score	0.792787 (rank : 8)
Query Neighborhood Hits	353	Target Neighborhood Hits	425	Shared Neighborhood Hits	258
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB1_HUMAN
θ value	1.2411e-41 (rank : 8)	NC score	0.805267 (rank : 7)
Query Neighborhood Hits	353	Target Neighborhood Hits	383	Shared Neighborhood Hits	252
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENG1_MOUSE
θ value	3.74554e-30 (rank : 9)	NC score	0.701548 (rank : 9)
Query Neighborhood Hits	353	Target Neighborhood Hits	531	Shared Neighborhood Hits	231
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG1_HUMAN
θ value	1.4233e-29 (rank : 10)	NC score	0.694797 (rank : 10)
Query Neighborhood Hits	353	Target Neighborhood Hits	544	Shared Neighborhood Hits	231
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG2_MOUSE
θ value	1.47289e-26 (rank : 11)	NC score	0.671417 (rank : 13)
Query Neighborhood Hits	353	Target Neighborhood Hits	463	Shared Neighborhood Hits	235
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENG2_HUMAN
θ value	1.92365e-26 (rank : 12)	NC score	0.669390 (rank : 14)
Query Neighborhood Hits	353	Target Neighborhood Hits	471	Shared Neighborhood Hits	236
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG3_MOUSE
θ value	1.80048e-24 (rank : 13)	NC score	0.679336 (rank : 11)
Query Neighborhood Hits	353	Target Neighborhood Hits	467	Shared Neighborhood Hits	222
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_HUMAN
θ value	2.35151e-24 (rank : 14)	NC score	0.678632 (rank : 12)
Query Neighborhood Hits	353	Target Neighborhood Hits	455	Shared Neighborhood Hits	221
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CEND3_HUMAN
θ value	8.65492e-19 (rank : 15)	NC score	0.515320 (rank : 33)
Query Neighborhood Hits	353	Target Neighborhood Hits	275	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND2_HUMAN
θ value	4.29542e-18 (rank : 16)	NC score	0.524224 (rank : 32)
Query Neighborhood Hits	353	Target Neighborhood Hits	166	Shared Neighborhood Hits	61
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CEND3_MOUSE
θ value	2.7842e-17 (rank : 17)	NC score	0.508239 (rank : 34)
Query Neighborhood Hits	353	Target Neighborhood Hits	228	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND1_HUMAN
θ value	3.40345e-15 (rank : 18)	NC score	0.534002 (rank : 30)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

SMAP1_MOUSE
θ value	4.44505e-15 (rank : 19)	NC score	0.664287 (rank : 16)
Query Neighborhood Hits	353	Target Neighborhood Hits	120	Shared Neighborhood Hits	42
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

CEND1_MOUSE
θ value	7.58209e-15 (rank : 20)	NC score	0.531905 (rank : 31)
Query Neighborhood Hits	353	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CENA1_HUMAN
θ value	1.68911e-14 (rank : 21)	NC score	0.665315 (rank : 15)
Query Neighborhood Hits	353	Target Neighborhood Hits	87	Shared Neighborhood Hits	52
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

SMAP1_HUMAN
θ value	3.76295e-14 (rank : 22)	NC score	0.661978 (rank : 18)
Query Neighborhood Hits	353	Target Neighborhood Hits	98	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	7.09661e-13 (rank : 23)	NC score	0.661237 (rank : 19)
Query Neighborhood Hits	353	Target Neighborhood Hits	74	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	7.09661e-13 (rank : 24)	NC score	0.660187 (rank : 20)
Query Neighborhood Hits	353	Target Neighborhood Hits	70	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

ARFG1_MOUSE
θ value	3.52202e-12 (rank : 25)	NC score	0.654754 (rank : 21)
Query Neighborhood Hits	353	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

CENA2_MOUSE
θ value	4.59992e-12 (rank : 26)	NC score	0.634837 (rank : 26)
Query Neighborhood Hits	353	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

ARFG1_HUMAN
θ value	6.00763e-12 (rank : 27)	NC score	0.639608 (rank : 25)
Query Neighborhood Hits	353	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

CENA2_HUMAN
θ value	7.84624e-12 (rank : 28)	NC score	0.624843 (rank : 27)
Query Neighborhood Hits	353	Target Neighborhood Hits	83	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

GIT2_HUMAN
θ value	2.52405e-10 (rank : 29)	NC score	0.653417 (rank : 22)
Query Neighborhood Hits	353	Target Neighborhood Hits	381	Shared Neighborhood Hits	245
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

GIT2_MOUSE
θ value	2.52405e-10 (rank : 30)	NC score	0.663809 (rank : 17)
Query Neighborhood Hits	353	Target Neighborhood Hits	323	Shared Neighborhood Hits	233
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

GIT1_HUMAN
θ value	1.25267e-09 (rank : 31)	NC score	0.642805 (rank : 23)
Query Neighborhood Hits	353	Target Neighborhood Hits	336	Shared Neighborhood Hits	231
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	1.25267e-09 (rank : 32)	NC score	0.642469 (rank : 24)
Query Neighborhood Hits	353	Target Neighborhood Hits	341	Shared Neighborhood Hits	234
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

ARFG3_MOUSE
θ value	2.13673e-09 (rank : 33)	NC score	0.615977 (rank : 29)
Query Neighborhood Hits	353	Target Neighborhood Hits	80	Shared Neighborhood Hits	38
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_HUMAN
θ value	2.79066e-09 (rank : 34)	NC score	0.619298 (rank : 28)
Query Neighborhood Hits	353	Target Neighborhood Hits	56	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

EHMT1_HUMAN
θ value	1.99992e-07 (rank : 35)	NC score	0.374655 (rank : 119)
Query Neighborhood Hits	353	Target Neighborhood Hits	417	Shared Neighborhood Hits	230
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ANKR6_HUMAN
θ value	7.59969e-07 (rank : 36)	NC score	0.427706 (rank : 40)
Query Neighborhood Hits	353	Target Neighborhood Hits	439	Shared Neighborhood Hits	233
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

MIB2_HUMAN
θ value	1.87187e-05 (rank : 37)	NC score	0.384619 (rank : 95)
Query Neighborhood Hits	353	Target Neighborhood Hits	438	Shared Neighborhood Hits	227
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ANK3_HUMAN
θ value	2.44474e-05 (rank : 38)	NC score	0.394120 (rank : 79)
Query Neighborhood Hits	353	Target Neighborhood Hits	853	Shared Neighborhood Hits	243
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR10_HUMAN
θ value	2.44474e-05 (rank : 39)	NC score	0.419253 (rank : 42)
Query Neighborhood Hits	353	Target Neighborhood Hits	289	Shared Neighborhood Hits	218
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR23_MOUSE
θ value	2.44474e-05 (rank : 40)	NC score	0.406214 (rank : 54)
Query Neighborhood Hits	353	Target Neighborhood Hits	296	Shared Neighborhood Hits	225
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANK1_HUMAN
θ value	3.19293e-05 (rank : 41)	NC score	0.404324 (rank : 55)
Query Neighborhood Hits	353	Target Neighborhood Hits	416	Shared Neighborhood Hits	227
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK2_HUMAN
θ value	4.1701e-05 (rank : 42)	NC score	0.374172 (rank : 120)
Query Neighborhood Hits	353	Target Neighborhood Hits	1615	Shared Neighborhood Hits	262
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BARD1_HUMAN
θ value	5.44631e-05 (rank : 43)	NC score	0.379755 (rank : 105)
Query Neighborhood Hits	353	Target Neighborhood Hits	427	Shared Neighborhood Hits	223
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

CTTB2_HUMAN
θ value	5.44631e-05 (rank : 44)	NC score	0.355092 (rank : 145)
Query Neighborhood Hits	353	Target Neighborhood Hits	1061	Shared Neighborhood Hits	259
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR39_HUMAN
θ value	7.1131e-05 (rank : 45)	NC score	0.429732 (rank : 38)
Query Neighborhood Hits	353	Target Neighborhood Hits	285	Shared Neighborhood Hits	224
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

PA2G6_MOUSE
θ value	9.29e-05 (rank : 46)	NC score	0.401889 (rank : 59)
Query Neighborhood Hits	353	Target Neighborhood Hits	293	Shared Neighborhood Hits	226
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

MIB2_MOUSE
θ value	0.000121331 (rank : 47)	NC score	0.381692 (rank : 100)
Query Neighborhood Hits	353	Target Neighborhood Hits	409	Shared Neighborhood Hits	226
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ANR39_MOUSE
θ value	0.000158464 (rank : 48)	NC score	0.428254 (rank : 39)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	223
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR22_HUMAN
θ value	0.00020696 (rank : 49)	NC score	0.424090 (rank : 41)
Query Neighborhood Hits	353	Target Neighborhood Hits	243	Shared Neighborhood Hits	207
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANS4B_MOUSE
θ value	0.00020696 (rank : 50)	NC score	0.410926 (rank : 48)
Query Neighborhood Hits	353	Target Neighborhood Hits	294	Shared Neighborhood Hits	213
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANR23_HUMAN
θ value	0.000270298 (rank : 51)	NC score	0.410115 (rank : 49)
Query Neighborhood Hits	353	Target Neighborhood Hits	291	Shared Neighborhood Hits	226
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANR42_HUMAN
θ value	0.000270298 (rank : 52)	NC score	0.414937 (rank : 43)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	224
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

HECD1_HUMAN
θ value	0.000270298 (rank : 53)	NC score	0.332781 (rank : 186)
Query Neighborhood Hits	353	Target Neighborhood Hits	371	Shared Neighborhood Hits	224
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

USH1G_HUMAN
θ value	0.000270298 (rank : 54)	NC score	0.400247 (rank : 63)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	217
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	0.000270298 (rank : 55)	NC score	0.400461 (rank : 62)
Query Neighborhood Hits	353	Target Neighborhood Hits	271	Shared Neighborhood Hits	217
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ANR37_MOUSE
θ value	0.00035302 (rank : 56)	NC score	0.445810 (rank : 36)
Query Neighborhood Hits	353	Target Neighborhood Hits	237	Shared Neighborhood Hits	205
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANR44_HUMAN
θ value	0.00035302 (rank : 57)	NC score	0.396992 (rank : 72)
Query Neighborhood Hits	353	Target Neighborhood Hits	318	Shared Neighborhood Hits	226
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

DAPK1_MOUSE
θ value	0.00035302 (rank : 58)	NC score	0.178824 (rank : 287)
Query Neighborhood Hits	353	Target Neighborhood Hits	1138	Shared Neighborhood Hits	229
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

GABP2_HUMAN
θ value	0.00035302 (rank : 59)	NC score	0.409479 (rank : 51)
Query Neighborhood Hits	353	Target Neighborhood Hits	454	Shared Neighborhood Hits	235
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ANK1_MOUSE
θ value	0.000461057 (rank : 60)	NC score	0.402957 (rank : 58)
Query Neighborhood Hits	353	Target Neighborhood Hits	430	Shared Neighborhood Hits	230
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ASB16_MOUSE
θ value	0.000461057 (rank : 61)	NC score	0.385420 (rank : 92)
Query Neighborhood Hits	353	Target Neighborhood Hits	306	Shared Neighborhood Hits	225
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

GABP2_MOUSE
θ value	0.000461057 (rank : 62)	NC score	0.409700 (rank : 50)
Query Neighborhood Hits	353	Target Neighborhood Hits	429	Shared Neighborhood Hits	233
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

OPHN1_MOUSE
θ value	0.000461057 (rank : 63)	NC score	0.191845 (rank : 277)
Query Neighborhood Hits	353	Target Neighborhood Hits	174	Shared Neighborhood Hits	25
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

BARD1_MOUSE
θ value	0.000602161 (rank : 64)	NC score	0.373328 (rank : 124)
Query Neighborhood Hits	353	Target Neighborhood Hits	411	Shared Neighborhood Hits	221
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

CSKI1_MOUSE
θ value	0.000602161 (rank : 65)	NC score	0.376590 (rank : 113)
Query Neighborhood Hits	353	Target Neighborhood Hits	1031	Shared Neighborhood Hits	252
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANS4B_HUMAN
θ value	0.000786445 (rank : 66)	NC score	0.409058 (rank : 52)
Query Neighborhood Hits	353	Target Neighborhood Hits	289	Shared Neighborhood Hits	215
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

MIB1_HUMAN
θ value	0.00102713 (rank : 67)	NC score	0.374697 (rank : 118)
Query Neighborhood Hits	353	Target Neighborhood Hits	470	Shared Neighborhood Hits	226
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	0.00102713 (rank : 68)	NC score	0.374760 (rank : 117)
Query Neighborhood Hits	353	Target Neighborhood Hits	471	Shared Neighborhood Hits	227
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MYPT2_HUMAN
θ value	0.00102713 (rank : 69)	NC score	0.388718 (rank : 89)
Query Neighborhood Hits	353	Target Neighborhood Hits	707	Shared Neighborhood Hits	250
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ANR10_MOUSE
θ value	0.00134147 (rank : 70)	NC score	0.414543 (rank : 44)
Query Neighborhood Hits	353	Target Neighborhood Hits	273	Shared Neighborhood Hits	217
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR45_HUMAN
θ value	0.00134147 (rank : 71)	NC score	0.344595 (rank : 164)
Query Neighborhood Hits	353	Target Neighborhood Hits	201	Shared Neighborhood Hits	159
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ASB16_HUMAN
θ value	0.00134147 (rank : 72)	NC score	0.388113 (rank : 90)
Query Neighborhood Hits	353	Target Neighborhood Hits	286	Shared Neighborhood Hits	224
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

CSKI2_HUMAN
θ value	0.00134147 (rank : 73)	NC score	0.390505 (rank : 82)
Query Neighborhood Hits	353	Target Neighborhood Hits	747	Shared Neighborhood Hits	251
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	0.00134147 (rank : 74)	NC score	0.389814 (rank : 85)
Query Neighborhood Hits	353	Target Neighborhood Hits	812	Shared Neighborhood Hits	249
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANR37_HUMAN
θ value	0.00175202 (rank : 75)	NC score	0.434510 (rank : 37)
Query Neighborhood Hits	353	Target Neighborhood Hits	247	Shared Neighborhood Hits	211
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ASB2_MOUSE
θ value	0.00175202 (rank : 76)	NC score	0.376695 (rank : 112)
Query Neighborhood Hits	353	Target Neighborhood Hits	321	Shared Neighborhood Hits	223
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

CSKI1_HUMAN
θ value	0.00175202 (rank : 77)	NC score	0.378042 (rank : 108)
Query Neighborhood Hits	353	Target Neighborhood Hits	997	Shared Neighborhood Hits	254
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

IASPP_MOUSE
θ value	0.00175202 (rank : 78)	NC score	0.276356 (rank : 233)
Query Neighborhood Hits	353	Target Neighborhood Hits	1024	Shared Neighborhood Hits	235
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ANKR1_MOUSE
θ value	0.00228821 (rank : 79)	NC score	0.404135 (rank : 56)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	225
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANKR2_HUMAN
θ value	0.00228821 (rank : 80)	NC score	0.398949 (rank : 67)
Query Neighborhood Hits	353	Target Neighborhood Hits	321	Shared Neighborhood Hits	231
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR42_MOUSE
θ value	0.00228821 (rank : 81)	NC score	0.411840 (rank : 47)
Query Neighborhood Hits	353	Target Neighborhood Hits	334	Shared Neighborhood Hits	229
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

MYPT1_HUMAN
θ value	0.00228821 (rank : 82)	NC score	0.394511 (rank : 78)
Query Neighborhood Hits	353	Target Neighborhood Hits	723	Shared Neighborhood Hits	247
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MYPT1_MOUSE
θ value	0.00228821 (rank : 83)	NC score	0.401049 (rank : 61)
Query Neighborhood Hits	353	Target Neighborhood Hits	539	Shared Neighborhood Hits	232
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

NUD12_MOUSE
θ value	0.00228821 (rank : 84)	NC score	0.291013 (rank : 222)
Query Neighborhood Hits	353	Target Neighborhood Hits	243	Shared Neighborhood Hits	191
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

RHG26_HUMAN
θ value	0.00228821 (rank : 85)	NC score	0.153959 (rank : 301)
Query Neighborhood Hits	353	Target Neighborhood Hits	281	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

SHAN1_HUMAN
θ value	0.00228821 (rank : 86)	NC score	0.343336 (rank : 169)
Query Neighborhood Hits	353	Target Neighborhood Hits	1041	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANKR1_HUMAN
θ value	0.00298849 (rank : 87)	NC score	0.401081 (rank : 60)
Query Neighborhood Hits	353	Target Neighborhood Hits	308	Shared Neighborhood Hits	227
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANR35_HUMAN
θ value	0.00298849 (rank : 88)	NC score	0.375105 (rank : 116)
Query Neighborhood Hits	353	Target Neighborhood Hits	784	Shared Neighborhood Hits	252
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

CT086_HUMAN
θ value	0.00298849 (rank : 89)	NC score	0.460661 (rank : 35)
Query Neighborhood Hits	353	Target Neighborhood Hits	277	Shared Neighborhood Hits	219
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

DP13B_HUMAN
θ value	0.00298849 (rank : 90)	NC score	0.185463 (rank : 281)
Query Neighborhood Hits	353	Target Neighborhood Hits	58	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

SNCAP_HUMAN
θ value	0.00298849 (rank : 91)	NC score	0.368101 (rank : 128)
Query Neighborhood Hits	353	Target Neighborhood Hits	313	Shared Neighborhood Hits	203
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

TNKS2_HUMAN
θ value	0.00298849 (rank : 92)	NC score	0.389844 (rank : 84)
Query Neighborhood Hits	353	Target Neighborhood Hits	361	Shared Neighborhood Hits	230
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR52_HUMAN
θ value	0.00390308 (rank : 93)	NC score	0.397140 (rank : 71)
Query Neighborhood Hits	353	Target Neighborhood Hits	322	Shared Neighborhood Hits	226
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
θ value	0.00390308 (rank : 94)	NC score	0.398386 (rank : 68)
Query Neighborhood Hits	353	Target Neighborhood Hits	318	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ASB7_HUMAN
θ value	0.00390308 (rank : 95)	NC score	0.383642 (rank : 97)
Query Neighborhood Hits	353	Target Neighborhood Hits	296	Shared Neighborhood Hits	225
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	0.00390308 (rank : 96)	NC score	0.383824 (rank : 96)
Query Neighborhood Hits	353	Target Neighborhood Hits	296	Shared Neighborhood Hits	225
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

GABP3_MOUSE
θ value	0.00390308 (rank : 97)	NC score	0.413754 (rank : 45)
Query Neighborhood Hits	353	Target Neighborhood Hits	330	Shared Neighborhood Hits	226
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ANR50_HUMAN
θ value	0.00509761 (rank : 98)	NC score	0.389438 (rank : 86)
Query Neighborhood Hits	353	Target Neighborhood Hits	361	Shared Neighborhood Hits	226
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

IKBE_MOUSE
θ value	0.00509761 (rank : 99)	NC score	0.381410 (rank : 102)
Query Neighborhood Hits	353	Target Neighborhood Hits	308	Shared Neighborhood Hits	226
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANR28_HUMAN
θ value	0.00665767 (rank : 100)	NC score	0.393790 (rank : 81)
Query Neighborhood Hits	353	Target Neighborhood Hits	314	Shared Neighborhood Hits	227
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

DAPK1_HUMAN
θ value	0.00665767 (rank : 101)	NC score	0.170782 (rank : 291)
Query Neighborhood Hits	353	Target Neighborhood Hits	1130	Shared Neighborhood Hits	228
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

RAI14_MOUSE
θ value	0.00665767 (rank : 102)	NC score	0.300539 (rank : 215)
Query Neighborhood Hits	353	Target Neighborhood Hits	1505	Shared Neighborhood Hits	262
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RIPK4_HUMAN
θ value	0.00665767 (rank : 103)	NC score	0.238738 (rank : 255)
Query Neighborhood Hits	353	Target Neighborhood Hits	1094	Shared Neighborhood Hits	230
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANR28_MOUSE
θ value	0.00869519 (rank : 104)	NC score	0.394728 (rank : 76)
Query Neighborhood Hits	353	Target Neighborhood Hits	314	Shared Neighborhood Hits	227
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

PA2G6_HUMAN
θ value	0.00869519 (rank : 105)	NC score	0.395130 (rank : 75)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	224
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

TNI3K_MOUSE
θ value	0.00869519 (rank : 106)	NC score	0.197665 (rank : 274)
Query Neighborhood Hits	353	Target Neighborhood Hits	1079	Shared Neighborhood Hits	229
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANKR2_MOUSE
θ value	0.0113563 (rank : 107)	NC score	0.397431 (rank : 70)
Query Neighborhood Hits	353	Target Neighborhood Hits	312	Shared Neighborhood Hits	228
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR41_HUMAN
θ value	0.0113563 (rank : 108)	NC score	0.399371 (rank : 64)
Query Neighborhood Hits	353	Target Neighborhood Hits	332	Shared Neighborhood Hits	212
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

NUPL_HUMAN
θ value	0.0113563 (rank : 109)	NC score	0.398982 (rank : 66)
Query Neighborhood Hits	353	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

NUPL_MOUSE
θ value	0.0113563 (rank : 110)	NC score	0.394571 (rank : 77)
Query Neighborhood Hits	353	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

PKHA6_MOUSE
θ value	0.0113563 (rank : 111)	NC score	0.137393 (rank : 304)
Query Neighborhood Hits	353	Target Neighborhood Hits	591	Shared Neighborhood Hits	67
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

ANR45_MOUSE
θ value	0.0148317 (rank : 112)	NC score	0.367831 (rank : 130)
Query Neighborhood Hits	353	Target Neighborhood Hits	204	Shared Neighborhood Hits	163
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

DGKI_HUMAN
θ value	0.0148317 (rank : 113)	NC score	0.194798 (rank : 276)
Query Neighborhood Hits	353	Target Neighborhood Hits	609	Shared Neighborhood Hits	188
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

NUD12_HUMAN
θ value	0.0148317 (rank : 114)	NC score	0.278578 (rank : 232)
Query Neighborhood Hits	353	Target Neighborhood Hits	222	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

RAI14_HUMAN
θ value	0.0148317 (rank : 115)	NC score	0.314074 (rank : 198)
Query Neighborhood Hits	353	Target Neighborhood Hits	1367	Shared Neighborhood Hits	265
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ASB2_HUMAN
θ value	0.0193708 (rank : 116)	NC score	0.383449 (rank : 98)
Query Neighborhood Hits	353	Target Neighborhood Hits	309	Shared Neighborhood Hits	225
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

IASPP_HUMAN
θ value	0.0193708 (rank : 117)	NC score	0.291255 (rank : 221)
Query Neighborhood Hits	353	Target Neighborhood Hits	688	Shared Neighborhood Hits	228
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TNI3K_HUMAN
θ value	0.0193708 (rank : 118)	NC score	0.201612 (rank : 266)
Query Neighborhood Hits	353	Target Neighborhood Hits	1084	Shared Neighborhood Hits	229
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNKS1_HUMAN
θ value	0.0193708 (rank : 119)	NC score	0.393913 (rank : 80)
Query Neighborhood Hits	353	Target Neighborhood Hits	477	Shared Neighborhood Hits	238
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ASB8_HUMAN
θ value	0.0252991 (rank : 120)	NC score	0.395244 (rank : 74)
Query Neighborhood Hits	353	Target Neighborhood Hits	294	Shared Neighborhood Hits	223
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
θ value	0.0252991 (rank : 121)	NC score	0.395374 (rank : 73)
Query Neighborhood Hits	353	Target Neighborhood Hits	293	Shared Neighborhood Hits	223
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ILK1_HUMAN
θ value	0.0252991 (rank : 122)	NC score	0.240213 (rank : 254)
Query Neighborhood Hits	353	Target Neighborhood Hits	857	Shared Neighborhood Hits	223
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	0.0252991 (rank : 123)	NC score	0.248973 (rank : 246)
Query Neighborhood Hits	353	Target Neighborhood Hits	848	Shared Neighborhood Hits	223
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

INVS_HUMAN
θ value	0.0252991 (rank : 124)	NC score	0.381161 (rank : 103)
Query Neighborhood Hits	353	Target Neighborhood Hits	455	Shared Neighborhood Hits	235
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ZDH17_HUMAN
θ value	0.0252991 (rank : 125)	NC score	0.343993 (rank : 165)
Query Neighborhood Hits	353	Target Neighborhood Hits	334	Shared Neighborhood Hits	225
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

EHMT2_MOUSE
θ value	0.0330416 (rank : 126)	NC score	0.358397 (rank : 139)
Query Neighborhood Hits	353	Target Neighborhood Hits	750	Shared Neighborhood Hits	243
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

HRBL_MOUSE
θ value	0.0330416 (rank : 127)	NC score	0.340098 (rank : 177)
Query Neighborhood Hits	353	Target Neighborhood Hits	269	Shared Neighborhood Hits	50
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

INVS_MOUSE
θ value	0.0330416 (rank : 128)	NC score	0.379751 (rank : 106)
Query Neighborhood Hits	353	Target Neighborhood Hits	609	Shared Neighborhood Hits	234
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANKR7_HUMAN
θ value	0.0431538 (rank : 129)	NC score	0.350500 (rank : 153)
Query Neighborhood Hits	353	Target Neighborhood Hits	286	Shared Neighborhood Hits	222
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANR19_HUMAN
θ value	0.0431538 (rank : 130)	NC score	0.346394 (rank : 162)
Query Neighborhood Hits	353	Target Neighborhood Hits	276	Shared Neighborhood Hits	220
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

EHMT2_HUMAN
θ value	0.0431538 (rank : 131)	NC score	0.368047 (rank : 129)
Query Neighborhood Hits	353	Target Neighborhood Hits	498	Shared Neighborhood Hits	234
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PSD10_HUMAN
θ value	0.0431538 (rank : 132)	NC score	0.406466 (rank : 53)
Query Neighborhood Hits	353	Target Neighborhood Hits	301	Shared Neighborhood Hits	226
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

TRPA1_MOUSE
θ value	0.0431538 (rank : 133)	NC score	0.371972 (rank : 126)
Query Neighborhood Hits	353	Target Neighborhood Hits	343	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ANFY1_HUMAN
θ value	0.0563607 (rank : 134)	NC score	0.338827 (rank : 179)
Query Neighborhood Hits	353	Target Neighborhood Hits	480	Shared Neighborhood Hits	229
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_MOUSE
θ value	0.0563607 (rank : 135)	NC score	0.337499 (rank : 181)
Query Neighborhood Hits	353	Target Neighborhood Hits	480	Shared Neighborhood Hits	229
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR25_HUMAN
θ value	0.0563607 (rank : 136)	NC score	0.299119 (rank : 217)
Query Neighborhood Hits	353	Target Neighborhood Hits	350	Shared Neighborhood Hits	219
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ASB13_HUMAN
θ value	0.0563607 (rank : 137)	NC score	0.377549 (rank : 110)
Query Neighborhood Hits	353	Target Neighborhood Hits	293	Shared Neighborhood Hits	223
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_MOUSE
θ value	0.0563607 (rank : 138)	NC score	0.377639 (rank : 109)
Query Neighborhood Hits	353	Target Neighborhood Hits	293	Shared Neighborhood Hits	223
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB15_MOUSE
θ value	0.0563607 (rank : 139)	NC score	0.348696 (rank : 157)
Query Neighborhood Hits	353	Target Neighborhood Hits	292	Shared Neighborhood Hits	219
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

BCL3_HUMAN
θ value	0.0563607 (rank : 140)	NC score	0.387375 (rank : 91)
Query Neighborhood Hits	353	Target Neighborhood Hits	324	Shared Neighborhood Hits	226
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

FANK1_HUMAN
θ value	0.0563607 (rank : 141)	NC score	0.378145 (rank : 107)
Query Neighborhood Hits	353	Target Neighborhood Hits	326	Shared Neighborhood Hits	223
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

FANK1_MOUSE
θ value	0.0563607 (rank : 142)	NC score	0.381489 (rank : 101)
Query Neighborhood Hits	353	Target Neighborhood Hits	325	Shared Neighborhood Hits	223
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

HRBL_HUMAN
θ value	0.0563607 (rank : 143)	NC score	0.349680 (rank : 154)
Query Neighborhood Hits	353	Target Neighborhood Hits	179	Shared Neighborhood Hits	42
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

IKBB_MOUSE
θ value	0.0563607 (rank : 144)	NC score	0.399248 (rank : 65)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	222
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ILK_MOUSE
θ value	0.0563607 (rank : 145)	NC score	0.236768 (rank : 257)
Query Neighborhood Hits	353	Target Neighborhood Hits	858	Shared Neighborhood Hits	224
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

OSBL3_MOUSE
θ value	0.0563607 (rank : 146)	NC score	0.088133 (rank : 324)
Query Neighborhood Hits	353	Target Neighborhood Hits	86	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PSD10_MOUSE
θ value	0.0563607 (rank : 147)	NC score	0.404002 (rank : 57)
Query Neighborhood Hits	353	Target Neighborhood Hits	293	Shared Neighborhood Hits	225
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ZDH17_MOUSE
θ value	0.0563607 (rank : 148)	NC score	0.340767 (rank : 175)
Query Neighborhood Hits	353	Target Neighborhood Hits	328	Shared Neighborhood Hits	224
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

MAGE1_HUMAN
θ value	0.0736092 (rank : 149)	NC score	0.042955 (rank : 386)
Query Neighborhood Hits	353	Target Neighborhood Hits	1389	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

OSBL3_HUMAN
θ value	0.0736092 (rank : 150)	NC score	0.090027 (rank : 321)
Query Neighborhood Hits	353	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

TRPA1_HUMAN
θ value	0.0736092 (rank : 151)	NC score	0.362408 (rank : 134)
Query Neighborhood Hits	353	Target Neighborhood Hits	339	Shared Neighborhood Hits	226
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ANR25_MOUSE
θ value	0.0961366 (rank : 152)	NC score	0.284032 (rank : 227)
Query Neighborhood Hits	353	Target Neighborhood Hits	398	Shared Neighborhood Hits	215
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ASB10_MOUSE
θ value	0.0961366 (rank : 153)	NC score	0.389983 (rank : 83)
Query Neighborhood Hits	353	Target Neighborhood Hits	301	Shared Neighborhood Hits	226
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

MYH11_HUMAN
θ value	0.0961366 (rank : 154)	NC score	0.035771 (rank : 395)
Query Neighborhood Hits	353	Target Neighborhood Hits	1806	Shared Neighborhood Hits	80
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	0.0961366 (rank : 155)	NC score	0.036297 (rank : 393)
Query Neighborhood Hits	353	Target Neighborhood Hits	1777	Shared Neighborhood Hits	80
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NFH_MOUSE
θ value	0.0961366 (rank : 156)	NC score	0.028539 (rank : 424)
Query Neighborhood Hits	353	Target Neighborhood Hits	2247	Shared Neighborhood Hits	107
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

OSBL1_HUMAN
θ value	0.0961366 (rank : 157)	NC score	0.299705 (rank : 216)
Query Neighborhood Hits	353	Target Neighborhood Hits	368	Shared Neighborhood Hits	231
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PKHA1_HUMAN
θ value	0.0961366 (rank : 158)	NC score	0.133754 (rank : 306)
Query Neighborhood Hits	353	Target Neighborhood Hits	127	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

POT15_HUMAN
θ value	0.0961366 (rank : 159)	NC score	0.322301 (rank : 191)
Query Neighborhood Hits	353	Target Neighborhood Hits	893	Shared Neighborhood Hits	251
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

UACA_MOUSE
θ value	0.0961366 (rank : 160)	NC score	0.236041 (rank : 258)
Query Neighborhood Hits	353	Target Neighborhood Hits	1620	Shared Neighborhood Hits	257
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

AIM1_HUMAN
θ value	0.125558 (rank : 161)	NC score	0.025983 (rank : 432)
Query Neighborhood Hits	353	Target Neighborhood Hits	247	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

ANKS6_HUMAN
θ value	0.125558 (rank : 162)	NC score	0.364358 (rank : 133)
Query Neighborhood Hits	353	Target Neighborhood Hits	411	Shared Neighborhood Hits	231
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR18_HUMAN
θ value	0.125558 (rank : 163)	NC score	0.282468 (rank : 229)
Query Neighborhood Hits	353	Target Neighborhood Hits	1106	Shared Neighborhood Hits	253
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ASB14_MOUSE
θ value	0.125558 (rank : 164)	NC score	0.353288 (rank : 149)
Query Neighborhood Hits	353	Target Neighborhood Hits	293	Shared Neighborhood Hits	224
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASPP2_HUMAN
θ value	0.125558 (rank : 165)	NC score	0.274529 (rank : 234)
Query Neighborhood Hits	353	Target Neighborhood Hits	1156	Shared Neighborhood Hits	261
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

FGD6_HUMAN
θ value	0.125558 (rank : 166)	NC score	0.033727 (rank : 399)
Query Neighborhood Hits	353	Target Neighborhood Hits	237	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

MPP8_HUMAN
θ value	0.125558 (rank : 167)	NC score	0.287223 (rank : 226)
Query Neighborhood Hits	353	Target Neighborhood Hits	948	Shared Neighborhood Hits	233
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MYLK_MOUSE
θ value	0.125558 (rank : 168)	NC score	0.007210 (rank : 451)
Query Neighborhood Hits	353	Target Neighborhood Hits	1489	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NFKB1_HUMAN
θ value	0.125558 (rank : 169)	NC score	0.319454 (rank : 195)
Query Neighborhood Hits	353	Target Neighborhood Hits	306	Shared Neighborhood Hits	224
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

PK1L1_HUMAN
θ value	0.125558 (rank : 170)	NC score	0.033738 (rank : 398)
Query Neighborhood Hits	353	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

PKHA6_HUMAN
θ value	0.125558 (rank : 171)	NC score	0.128629 (rank : 310)
Query Neighborhood Hits	353	Target Neighborhood Hits	556	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

WASIP_HUMAN
θ value	0.125558 (rank : 172)	NC score	0.052541 (rank : 366)
Query Neighborhood Hits	353	Target Neighborhood Hits	458	Shared Neighborhood Hits	32
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ANKK1_HUMAN
θ value	0.163984 (rank : 173)	NC score	0.237703 (rank : 256)
Query Neighborhood Hits	353	Target Neighborhood Hits	1075	Shared Neighborhood Hits	229
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

BCL3_MOUSE
θ value	0.163984 (rank : 174)	NC score	0.384774 (rank : 94)
Query Neighborhood Hits	353	Target Neighborhood Hits	388	Shared Neighborhood Hits	230
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

DP13B_MOUSE
θ value	0.163984 (rank : 175)	NC score	0.198992 (rank : 272)
Query Neighborhood Hits	353	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

IKBE_HUMAN
θ value	0.163984 (rank : 176)	NC score	0.368449 (rank : 127)
Query Neighborhood Hits	353	Target Neighborhood Hits	288	Shared Neighborhood Hits	222
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

MAST1_MOUSE
θ value	0.163984 (rank : 177)	NC score	0.003395 (rank : 459)
Query Neighborhood Hits	353	Target Neighborhood Hits	1123	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NFKB2_MOUSE
θ value	0.163984 (rank : 178)	NC score	0.310951 (rank : 203)
Query Neighborhood Hits	353	Target Neighborhood Hits	326	Shared Neighborhood Hits	222
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR29_HUMAN
θ value	0.21417 (rank : 179)	NC score	0.385036 (rank : 93)
Query Neighborhood Hits	353	Target Neighborhood Hits	294	Shared Neighborhood Hits	223
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ASB15_HUMAN
θ value	0.21417 (rank : 180)	NC score	0.357107 (rank : 141)
Query Neighborhood Hits	353	Target Neighborhood Hits	305	Shared Neighborhood Hits	225
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

MLL3_HUMAN
θ value	0.21417 (rank : 181)	NC score	0.033395 (rank : 400)
Query Neighborhood Hits	353	Target Neighborhood Hits	1644	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NOTC3_HUMAN
θ value	0.21417 (rank : 182)	NC score	0.179354 (rank : 286)
Query Neighborhood Hits	353	Target Neighborhood Hits	1062	Shared Neighborhood Hits	233
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	0.21417 (rank : 183)	NC score	0.180959 (rank : 284)
Query Neighborhood Hits	353	Target Neighborhood Hits	975	Shared Neighborhood Hits	235
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SRA1_HUMAN
θ value	0.21417 (rank : 184)	NC score	0.038554 (rank : 389)
Query Neighborhood Hits	353	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HD15, Q6NVU9, Q8IXM1, Q9HD13, Q9HD14	Gene names	SRA1
Domain Architecture	No domain graphic available
Description	Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP).

TCOF_HUMAN
θ value	0.21417 (rank : 185)	NC score	0.036641 (rank : 392)
Query Neighborhood Hits	353	Target Neighborhood Hits	543	Shared Neighborhood Hits	32
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

ANR21_HUMAN
θ value	0.279714 (rank : 186)	NC score	0.323161 (rank : 190)
Query Neighborhood Hits	353	Target Neighborhood Hits	864	Shared Neighborhood Hits	250
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

BSN_MOUSE
θ value	0.279714 (rank : 187)	NC score	0.050279 (rank : 381)
Query Neighborhood Hits	353	Target Neighborhood Hits	2057	Shared Neighborhood Hits	107
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NOTC1_HUMAN
θ value	0.279714 (rank : 188)	NC score	0.169181 (rank : 293)
Query Neighborhood Hits	353	Target Neighborhood Hits	906	Shared Neighborhood Hits	226
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

OSBL1_MOUSE
θ value	0.279714 (rank : 189)	NC score	0.294146 (rank : 220)
Query Neighborhood Hits	353	Target Neighborhood Hits	336	Shared Neighborhood Hits	228
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

A20A1_HUMAN
θ value	0.365318 (rank : 190)	NC score	0.305228 (rank : 209)
Query Neighborhood Hits	353	Target Neighborhood Hits	698	Shared Neighborhood Hits	245
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
θ value	0.365318 (rank : 191)	NC score	0.306585 (rank : 206)
Query Neighborhood Hits	353	Target Neighborhood Hits	716	Shared Neighborhood Hits	246
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A3_HUMAN
θ value	0.365318 (rank : 192)	NC score	0.306534 (rank : 207)
Query Neighborhood Hits	353	Target Neighborhood Hits	692	Shared Neighborhood Hits	246
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	0.365318 (rank : 193)	NC score	0.304648 (rank : 211)
Query Neighborhood Hits	353	Target Neighborhood Hits	710	Shared Neighborhood Hits	246
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

CLPB_HUMAN
θ value	0.365318 (rank : 194)	NC score	0.268456 (rank : 237)
Query Neighborhood Hits	353	Target Neighborhood Hits	265	Shared Neighborhood Hits	196
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

MYH1_HUMAN
θ value	0.365318 (rank : 195)	NC score	0.033361 (rank : 401)
Query Neighborhood Hits	353	Target Neighborhood Hits	1478	Shared Neighborhood Hits	63
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

OSTF1_MOUSE
θ value	0.365318 (rank : 196)	NC score	0.307337 (rank : 205)
Query Neighborhood Hits	353	Target Neighborhood Hits	467	Shared Neighborhood Hits	212
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

SPEG_HUMAN
θ value	0.365318 (rank : 197)	NC score	0.004755 (rank : 456)
Query Neighborhood Hits	353	Target Neighborhood Hits	1762	Shared Neighborhood Hits	47
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ANKK1_MOUSE
θ value	0.47712 (rank : 198)	NC score	0.233911 (rank : 259)
Query Neighborhood Hits	353	Target Neighborhood Hits	1072	Shared Neighborhood Hits	229
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANKS1_HUMAN
θ value	0.47712 (rank : 199)	NC score	0.357167 (rank : 140)
Query Neighborhood Hits	353	Target Neighborhood Hits	438	Shared Neighborhood Hits	229
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKS6_MOUSE
θ value	0.47712 (rank : 200)	NC score	0.354891 (rank : 146)
Query Neighborhood Hits	353	Target Neighborhood Hits	435	Shared Neighborhood Hits	232
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR26_MOUSE
θ value	0.47712 (rank : 201)	NC score	0.220466 (rank : 262)
Query Neighborhood Hits	353	Target Neighborhood Hits	1554	Shared Neighborhood Hits	265
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB4_MOUSE
θ value	0.47712 (rank : 202)	NC score	0.347212 (rank : 160)
Query Neighborhood Hits	353	Target Neighborhood Hits	265	Shared Neighborhood Hits	219
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

CDN2C_MOUSE
θ value	0.47712 (rank : 203)	NC score	0.351984 (rank : 151)
Query Neighborhood Hits	353	Target Neighborhood Hits	270	Shared Neighborhood Hits	217
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

FARP1_HUMAN
θ value	0.47712 (rank : 204)	NC score	0.034300 (rank : 397)
Query Neighborhood Hits	353	Target Neighborhood Hits	241	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

GOGB1_HUMAN
θ value	0.47712 (rank : 205)	NC score	0.032453 (rank : 408)
Query Neighborhood Hits	353	Target Neighborhood Hits	2297	Shared Neighborhood Hits	85
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MYO10_HUMAN
θ value	0.47712 (rank : 206)	NC score	0.061714 (rank : 342)
Query Neighborhood Hits	353	Target Neighborhood Hits	920	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

SSBP4_HUMAN
θ value	0.47712 (rank : 207)	NC score	0.027916 (rank : 425)
Query Neighborhood Hits	353	Target Neighborhood Hits	753	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

ANR49_HUMAN
θ value	0.62314 (rank : 208)	NC score	0.375393 (rank : 114)
Query Neighborhood Hits	353	Target Neighborhood Hits	282	Shared Neighborhood Hits	221
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ASB12_MOUSE
θ value	0.62314 (rank : 209)	NC score	0.341624 (rank : 170)
Query Neighborhood Hits	353	Target Neighborhood Hits	261	Shared Neighborhood Hits	217
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB6_HUMAN
θ value	0.62314 (rank : 210)	NC score	0.296025 (rank : 219)
Query Neighborhood Hits	353	Target Neighborhood Hits	256	Shared Neighborhood Hits	203
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CLPB_MOUSE
θ value	0.62314 (rank : 211)	NC score	0.290550 (rank : 224)
Query Neighborhood Hits	353	Target Neighborhood Hits	289	Shared Neighborhood Hits	203
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

FYCO1_HUMAN
θ value	0.62314 (rank : 212)	NC score	0.033093 (rank : 404)
Query Neighborhood Hits	353	Target Neighborhood Hits	1149	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

MTPN_MOUSE
θ value	0.62314 (rank : 213)	NC score	0.389407 (rank : 87)
Query Neighborhood Hits	353	Target Neighborhood Hits	269	Shared Neighborhood Hits	217
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

MYH2_HUMAN
θ value	0.62314 (rank : 214)	NC score	0.033348 (rank : 402)
Query Neighborhood Hits	353	Target Neighborhood Hits	1491	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

OSBL9_HUMAN
θ value	0.62314 (rank : 215)	NC score	0.072813 (rank : 330)
Query Neighborhood Hits	353	Target Neighborhood Hits	138	Shared Neighborhood Hits	38
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

TENS4_MOUSE
θ value	0.62314 (rank : 216)	NC score	0.026509 (rank : 430)
Query Neighborhood Hits	353	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

ZN291_HUMAN
θ value	0.62314 (rank : 217)	NC score	0.031401 (rank : 415)
Query Neighborhood Hits	353	Target Neighborhood Hits	647	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

ANKR5_HUMAN
θ value	0.813845 (rank : 218)	NC score	0.373795 (rank : 122)
Query Neighborhood Hits	353	Target Neighborhood Hits	297	Shared Neighborhood Hits	225
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKR5_MOUSE
θ value	0.813845 (rank : 219)	NC score	0.373808 (rank : 121)
Query Neighborhood Hits	353	Target Neighborhood Hits	298	Shared Neighborhood Hits	225
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKS1_MOUSE
θ value	0.813845 (rank : 220)	NC score	0.355311 (rank : 143)
Query Neighborhood Hits	353	Target Neighborhood Hits	453	Shared Neighborhood Hits	233
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

IKBA_HUMAN
θ value	0.813845 (rank : 221)	NC score	0.347272 (rank : 159)
Query Neighborhood Hits	353	Target Neighborhood Hits	280	Shared Neighborhood Hits	223
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ANR15_HUMAN
θ value	1.06291 (rank : 222)	NC score	0.341175 (rank : 174)
Query Neighborhood Hits	353	Target Neighborhood Hits	478	Shared Neighborhood Hits	234
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ASB6_MOUSE
θ value	1.06291 (rank : 223)	NC score	0.290866 (rank : 223)
Query Neighborhood Hits	353	Target Neighborhood Hits	264	Shared Neighborhood Hits	206
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASPP1_HUMAN
θ value	1.06291 (rank : 224)	NC score	0.262833 (rank : 239)
Query Neighborhood Hits	353	Target Neighborhood Hits	956	Shared Neighborhood Hits	250
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	1.06291 (rank : 225)	NC score	0.260607 (rank : 240)
Query Neighborhood Hits	353	Target Neighborhood Hits	1244	Shared Neighborhood Hits	259
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

DAPP1_MOUSE
θ value	1.06291 (rank : 226)	NC score	0.079003 (rank : 327)
Query Neighborhood Hits	353	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

GOGA2_MOUSE
θ value	1.06291 (rank : 227)	NC score	0.031152 (rank : 417)
Query Neighborhood Hits	353	Target Neighborhood Hits	944	Shared Neighborhood Hits	51
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

IKBA_MOUSE
θ value	1.06291 (rank : 228)	NC score	0.341280 (rank : 173)
Query Neighborhood Hits	353	Target Neighborhood Hits	283	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

NFKB1_MOUSE
θ value	1.06291 (rank : 229)	NC score	0.316536 (rank : 196)
Query Neighborhood Hits	353	Target Neighborhood Hits	300	Shared Neighborhood Hits	220
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

NOTC1_MOUSE
θ value	1.06291 (rank : 230)	NC score	0.139232 (rank : 303)
Query Neighborhood Hits	353	Target Neighborhood Hits	916	Shared Neighborhood Hits	216
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PKHA1_MOUSE
θ value	1.06291 (rank : 231)	NC score	0.128048 (rank : 311)
Query Neighborhood Hits	353	Target Neighborhood Hits	120	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

POTE8_HUMAN
θ value	1.06291 (rank : 232)	NC score	0.343568 (rank : 168)
Query Neighborhood Hits	353	Target Neighborhood Hits	337	Shared Neighborhood Hits	225
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

RECQ5_HUMAN
θ value	1.06291 (rank : 233)	NC score	0.017479 (rank : 439)
Query Neighborhood Hits	353	Target Neighborhood Hits	390	Shared Neighborhood Hits	24
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

TB182_HUMAN
θ value	1.06291 (rank : 234)	NC score	0.030661 (rank : 420)
Query Neighborhood Hits	353	Target Neighborhood Hits	414	Shared Neighborhood Hits	25
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

ANR16_HUMAN
θ value	1.38821 (rank : 235)	NC score	0.353696 (rank : 148)
Query Neighborhood Hits	353	Target Neighborhood Hits	286	Shared Neighborhood Hits	224
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR47_MOUSE
θ value	1.38821 (rank : 236)	NC score	0.319796 (rank : 193)
Query Neighborhood Hits	353	Target Neighborhood Hits	350	Shared Neighborhood Hits	220
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASB1_MOUSE
θ value	1.38821 (rank : 237)	NC score	0.336312 (rank : 184)
Query Neighborhood Hits	353	Target Neighborhood Hits	292	Shared Neighborhood Hits	218
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CDN2C_HUMAN
θ value	1.38821 (rank : 238)	NC score	0.352891 (rank : 150)
Query Neighborhood Hits	353	Target Neighborhood Hits	262	Shared Neighborhood Hits	217
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

MYH3_HUMAN
θ value	1.38821 (rank : 239)	NC score	0.032632 (rank : 406)
Query Neighborhood Hits	353	Target Neighborhood Hits	1660	Shared Neighborhood Hits	66
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

SASH1_MOUSE
θ value	1.38821 (rank : 240)	NC score	0.034734 (rank : 396)
Query Neighborhood Hits	353	Target Neighborhood Hits	263	Shared Neighborhood Hits	22
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

ZDH13_HUMAN
θ value	1.38821 (rank : 241)	NC score	0.321250 (rank : 192)
Query Neighborhood Hits	353	Target Neighborhood Hits	322	Shared Neighborhood Hits	223
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

AN30A_HUMAN
θ value	1.81305 (rank : 242)	NC score	0.248196 (rank : 249)
Query Neighborhood Hits	353	Target Neighborhood Hits	1119	Shared Neighborhood Hits	251
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANKY2_HUMAN
θ value	1.81305 (rank : 243)	NC score	0.313291 (rank : 200)
Query Neighborhood Hits	353	Target Neighborhood Hits	306	Shared Neighborhood Hits	210
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR12_HUMAN
θ value	1.81305 (rank : 244)	NC score	0.315082 (rank : 197)
Query Neighborhood Hits	353	Target Neighborhood Hits	1081	Shared Neighborhood Hits	255
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR26_HUMAN
θ value	1.81305 (rank : 245)	NC score	0.200531 (rank : 267)
Query Neighborhood Hits	353	Target Neighborhood Hits	1614	Shared Neighborhood Hits	262
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB9_HUMAN
θ value	1.81305 (rank : 246)	NC score	0.341414 (rank : 172)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	210
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

COBA1_MOUSE
θ value	1.81305 (rank : 247)	NC score	0.008856 (rank : 449)
Query Neighborhood Hits	353	Target Neighborhood Hits	487	Shared Neighborhood Hits	25
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

DAPP1_HUMAN
θ value	1.81305 (rank : 248)	NC score	0.070980 (rank : 336)
Query Neighborhood Hits	353	Target Neighborhood Hits	227	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

IRS2_HUMAN
θ value	1.81305 (rank : 249)	NC score	0.031883 (rank : 414)
Query Neighborhood Hits	353	Target Neighborhood Hits	262	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

MTMR5_HUMAN
θ value	1.81305 (rank : 250)	NC score	0.035997 (rank : 394)
Query Neighborhood Hits	353	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MTPN_HUMAN
θ value	1.81305 (rank : 251)	NC score	0.382976 (rank : 99)
Query Neighborhood Hits	353	Target Neighborhood Hits	269	Shared Neighborhood Hits	217
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

MYH1_MOUSE
θ value	1.81305 (rank : 252)	NC score	0.032725 (rank : 405)
Query Neighborhood Hits	353	Target Neighborhood Hits	1461	Shared Neighborhood Hits	65
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

NFKB2_HUMAN
θ value	1.81305 (rank : 253)	NC score	0.313660 (rank : 199)
Query Neighborhood Hits	353	Target Neighborhood Hits	325	Shared Neighborhood Hits	223
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

NOTC4_MOUSE
θ value	1.81305 (rank : 254)	NC score	0.204123 (rank : 265)
Query Neighborhood Hits	353	Target Neighborhood Hits	872	Shared Neighborhood Hits	226
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PP16A_MOUSE
θ value	1.81305 (rank : 255)	NC score	0.366957 (rank : 131)
Query Neighborhood Hits	353	Target Neighborhood Hits	318	Shared Neighborhood Hits	225
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

PP16B_HUMAN
θ value	1.81305 (rank : 256)	NC score	0.361575 (rank : 136)
Query Neighborhood Hits	353	Target Neighborhood Hits	307	Shared Neighborhood Hits	228
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

RAD50_MOUSE
θ value	1.81305 (rank : 257)	NC score	0.026632 (rank : 429)
Query Neighborhood Hits	353	Target Neighborhood Hits	1366	Shared Neighborhood Hits	56
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

WASIP_MOUSE
θ value	1.81305 (rank : 258)	NC score	0.042583 (rank : 387)
Query Neighborhood Hits	353	Target Neighborhood Hits	392	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ZDH13_MOUSE
θ value	1.81305 (rank : 259)	NC score	0.325713 (rank : 189)
Query Neighborhood Hits	353	Target Neighborhood Hits	329	Shared Neighborhood Hits	224
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ZN447_HUMAN
θ value	1.81305 (rank : 260)	NC score	-0.003063 (rank : 465)
Query Neighborhood Hits	353	Target Neighborhood Hits	899	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

AKAP1_MOUSE
θ value	2.36792 (rank : 261)	NC score	0.015328 (rank : 441)
Query Neighborhood Hits	353	Target Neighborhood Hits	198	Shared Neighborhood Hits	10
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

ANR38_HUMAN
θ value	2.36792 (rank : 262)	NC score	0.272397 (rank : 236)
Query Neighborhood Hits	353	Target Neighborhood Hits	443	Shared Neighborhood Hits	218
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR47_HUMAN
θ value	2.36792 (rank : 263)	NC score	0.305148 (rank : 210)
Query Neighborhood Hits	353	Target Neighborhood Hits	369	Shared Neighborhood Hits	218
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

IKBB_HUMAN
θ value	2.36792 (rank : 264)	NC score	0.381005 (rank : 104)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	225
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

MEF2B_HUMAN
θ value	2.36792 (rank : 265)	NC score	0.016706 (rank : 440)
Query Neighborhood Hits	353	Target Neighborhood Hits	150	Shared Neighborhood Hits	6
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

MYH10_HUMAN
θ value	2.36792 (rank : 266)	NC score	0.031910 (rank : 413)
Query Neighborhood Hits	353	Target Neighborhood Hits	1620	Shared Neighborhood Hits	71
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	2.36792 (rank : 267)	NC score	0.032020 (rank : 412)
Query Neighborhood Hits	353	Target Neighborhood Hits	1612	Shared Neighborhood Hits	73
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NACAM_MOUSE
θ value	2.36792 (rank : 268)	NC score	0.049601 (rank : 382)
Query Neighborhood Hits	353	Target Neighborhood Hits	1866	Shared Neighborhood Hits	79
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

OSBL6_HUMAN
θ value	2.36792 (rank : 269)	NC score	0.062685 (rank : 340)
Query Neighborhood Hits	353	Target Neighborhood Hits	101	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

AN13B_HUMAN
θ value	3.0926 (rank : 270)	NC score	0.248668 (rank : 248)
Query Neighborhood Hits	353	Target Neighborhood Hits	265	Shared Neighborhood Hits	213
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	3.0926 (rank : 271)	NC score	0.248761 (rank : 247)
Query Neighborhood Hits	353	Target Neighborhood Hits	276	Shared Neighborhood Hits	213
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ANR33_HUMAN
θ value	3.0926 (rank : 272)	NC score	0.312171 (rank : 201)
Query Neighborhood Hits	353	Target Neighborhood Hits	215	Shared Neighborhood Hits	190
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANRA2_HUMAN
θ value	3.0926 (rank : 273)	NC score	0.375369 (rank : 115)
Query Neighborhood Hits	353	Target Neighborhood Hits	288	Shared Neighborhood Hits	222
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB10_HUMAN
θ value	3.0926 (rank : 274)	NC score	0.389277 (rank : 88)
Query Neighborhood Hits	353	Target Neighborhood Hits	291	Shared Neighborhood Hits	225
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB4_HUMAN
θ value	3.0926 (rank : 275)	NC score	0.343717 (rank : 167)
Query Neighborhood Hits	353	Target Neighborhood Hits	264	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB5_HUMAN
θ value	3.0926 (rank : 276)	NC score	0.337809 (rank : 180)
Query Neighborhood Hits	353	Target Neighborhood Hits	283	Shared Neighborhood Hits	220
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

DGKZ_HUMAN
θ value	3.0926 (rank : 277)	NC score	0.172260 (rank : 289)
Query Neighborhood Hits	353	Target Neighborhood Hits	551	Shared Neighborhood Hits	189
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

MTMRD_HUMAN
θ value	3.0926 (rank : 278)	NC score	0.047698 (rank : 383)
Query Neighborhood Hits	353	Target Neighborhood Hits	135	Shared Neighborhood Hits	32
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

MYH13_HUMAN
θ value	3.0926 (rank : 279)	NC score	0.032168 (rank : 411)
Query Neighborhood Hits	353	Target Neighborhood Hits	1504	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

NOTC4_HUMAN
θ value	3.0926 (rank : 280)	NC score	0.199176 (rank : 271)
Query Neighborhood Hits	353	Target Neighborhood Hits	905	Shared Neighborhood Hits	232
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

OGFR_MOUSE
θ value	3.0926 (rank : 281)	NC score	0.036868 (rank : 391)
Query Neighborhood Hits	353	Target Neighborhood Hits	584	Shared Neighborhood Hits	28
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

OSBL6_MOUSE
θ value	3.0926 (rank : 282)	NC score	0.061554 (rank : 344)
Query Neighborhood Hits	353	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

PKHA5_HUMAN
θ value	3.0926 (rank : 283)	NC score	0.085135 (rank : 325)
Query Neighborhood Hits	353	Target Neighborhood Hits	455	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

TM108_HUMAN
θ value	3.0926 (rank : 284)	NC score	0.024903 (rank : 433)
Query Neighborhood Hits	353	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ACBD6_HUMAN
θ value	4.03905 (rank : 285)	NC score	0.356742 (rank : 142)
Query Neighborhood Hits	353	Target Neighborhood Hits	304	Shared Neighborhood Hits	222
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ACINU_MOUSE
θ value	4.03905 (rank : 286)	NC score	0.027158 (rank : 428)
Query Neighborhood Hits	353	Target Neighborhood Hits	712	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ANKY2_MOUSE
θ value	4.03905 (rank : 287)	NC score	0.298980 (rank : 218)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	210
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ASB1_HUMAN
θ value	4.03905 (rank : 288)	NC score	0.337126 (rank : 182)
Query Neighborhood Hits	353	Target Neighborhood Hits	291	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CNTRB_MOUSE
θ value	4.03905 (rank : 289)	NC score	0.030845 (rank : 418)
Query Neighborhood Hits	353	Target Neighborhood Hits	1029	Shared Neighborhood Hits	62
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

DISC1_HUMAN
θ value	4.03905 (rank : 290)	NC score	0.022726 (rank : 435)
Query Neighborhood Hits	353	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NRI5, O75045, Q5VT44, Q5VT45, Q8IXJ0, Q8IXJ1, Q9BX19, Q9NRI3, Q9NRI4	Gene names	DISC1, KIAA0457
Domain Architecture	No domain graphic available
Description	Disrupted in schizophrenia 1 protein.

FGD4_HUMAN
θ value	4.03905 (rank : 291)	NC score	0.027540 (rank : 426)
Query Neighborhood Hits	353	Target Neighborhood Hits	219	Shared Neighborhood Hits	29
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FOG1_HUMAN
θ value	4.03905 (rank : 292)	NC score	-0.001572 (rank : 462)
Query Neighborhood Hits	353	Target Neighborhood Hits	981	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GCC2_HUMAN
θ value	4.03905 (rank : 293)	NC score	0.029780 (rank : 423)
Query Neighborhood Hits	353	Target Neighborhood Hits	1558	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GOGA3_HUMAN
θ value	4.03905 (rank : 294)	NC score	0.030050 (rank : 421)
Query Neighborhood Hits	353	Target Neighborhood Hits	1317	Shared Neighborhood Hits	69
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA3_MOUSE
θ value	4.03905 (rank : 295)	NC score	0.030684 (rank : 419)
Query Neighborhood Hits	353	Target Neighborhood Hits	1437	Shared Neighborhood Hits	68
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

MYH4_MOUSE
θ value	4.03905 (rank : 296)	NC score	0.032318 (rank : 409)
Query Neighborhood Hits	353	Target Neighborhood Hits	1476	Shared Neighborhood Hits	63
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_HUMAN
θ value	4.03905 (rank : 297)	NC score	0.031230 (rank : 416)
Query Neighborhood Hits	353	Target Neighborhood Hits	1610	Shared Neighborhood Hits	67
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
θ value	4.03905 (rank : 298)	NC score	0.032307 (rank : 410)
Query Neighborhood Hits	353	Target Neighborhood Hits	1600	Shared Neighborhood Hits	67
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NOTC2_HUMAN
θ value	4.03905 (rank : 299)	NC score	0.171076 (rank : 290)
Query Neighborhood Hits	353	Target Neighborhood Hits	1113	Shared Neighborhood Hits	229
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	4.03905 (rank : 300)	NC score	0.170476 (rank : 292)
Query Neighborhood Hits	353	Target Neighborhood Hits	1069	Shared Neighborhood Hits	230
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

POT14_HUMAN
θ value	4.03905 (rank : 301)	NC score	0.319482 (rank : 194)
Query Neighborhood Hits	353	Target Neighborhood Hits	403	Shared Neighborhood Hits	223
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

RBP24_HUMAN
θ value	4.03905 (rank : 302)	NC score	0.029868 (rank : 422)
Query Neighborhood Hits	353	Target Neighborhood Hits	1559	Shared Neighborhood Hits	72
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RFXK_HUMAN
θ value	4.03905 (rank : 303)	NC score	0.351081 (rank : 152)
Query Neighborhood Hits	353	Target Neighborhood Hits	282	Shared Neighborhood Hits	218
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

TBC12_HUMAN
θ value	4.03905 (rank : 304)	NC score	0.006852 (rank : 452)
Query Neighborhood Hits	353	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

UACA_HUMAN
θ value	4.03905 (rank : 305)	NC score	0.241572 (rank : 252)
Query Neighborhood Hits	353	Target Neighborhood Hits	1622	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ANKS3_MOUSE
θ value	5.27518 (rank : 306)	NC score	0.355220 (rank : 144)
Query Neighborhood Hits	353	Target Neighborhood Hits	355	Shared Neighborhood Hits	227
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANRA2_MOUSE
θ value	5.27518 (rank : 307)	NC score	0.373766 (rank : 123)
Query Neighborhood Hits	353	Target Neighborhood Hits	287	Shared Neighborhood Hits	222
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

CLR59_HUMAN
θ value	5.27518 (rank : 308)	NC score	0.117469 (rank : 313)
Query Neighborhood Hits	353	Target Neighborhood Hits	163	Shared Neighborhood Hits	129
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

CSPG2_MOUSE
θ value	5.27518 (rank : 309)	NC score	0.010056 (rank : 447)
Query Neighborhood Hits	353	Target Neighborhood Hits	711	Shared Neighborhood Hits	30
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

ELOA3_HUMAN
θ value	5.27518 (rank : 310)	NC score	0.012423 (rank : 443)
Query Neighborhood Hits	353	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

MAVS_HUMAN
θ value	5.27518 (rank : 311)	NC score	0.022444 (rank : 436)
Query Neighborhood Hits	353	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MYH6_HUMAN
θ value	5.27518 (rank : 312)	NC score	0.032477 (rank : 407)
Query Neighborhood Hits	353	Target Neighborhood Hits	1426	Shared Neighborhood Hits	65
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NOL9_HUMAN
θ value	5.27518 (rank : 313)	NC score	0.014476 (rank : 442)
Query Neighborhood Hits	353	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SY16, Q4VBY3, Q6P472, Q7L4D6, Q96EE0, Q9H5L4	Gene names	NOL9
Domain Architecture	No domain graphic available
Description	Nucleolar protein 9.

OSBP1_HUMAN
θ value	5.27518 (rank : 314)	NC score	0.103786 (rank : 316)
Query Neighborhood Hits	353	Target Neighborhood Hits	180	Shared Neighborhood Hits	45
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

PP16A_HUMAN
θ value	5.27518 (rank : 315)	NC score	0.353732 (rank : 147)
Query Neighborhood Hits	353	Target Neighborhood Hits	340	Shared Neighborhood Hits	223
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

RFXK_MOUSE
θ value	5.27518 (rank : 316)	NC score	0.341528 (rank : 171)
Query Neighborhood Hits	353	Target Neighborhood Hits	273	Shared Neighborhood Hits	221
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

SGOL1_MOUSE
θ value	5.27518 (rank : 317)	NC score	0.011534 (rank : 444)
Query Neighborhood Hits	353	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CXH7, Q3U4K4, Q588H1, Q8BKW2	Gene names	Sgol1, Sgo1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1.

ZFHX2_HUMAN
θ value	5.27518 (rank : 318)	NC score	-0.002483 (rank : 463)
Query Neighborhood Hits	353	Target Neighborhood Hits	1178	Shared Neighborhood Hits	22
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

ACBD6_MOUSE
θ value	6.88961 (rank : 319)	NC score	0.359042 (rank : 138)
Query Neighborhood Hits	353	Target Neighborhood Hits	305	Shared Neighborhood Hits	225
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

AKAP2_MOUSE
θ value	6.88961 (rank : 320)	NC score	0.017678 (rank : 438)
Query Neighborhood Hits	353	Target Neighborhood Hits	385	Shared Neighborhood Hits	21
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ANKR9_MOUSE
θ value	6.88961 (rank : 321)	NC score	0.167993 (rank : 294)
Query Neighborhood Hits	353	Target Neighborhood Hits	120	Shared Neighborhood Hits	109
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANR11_HUMAN
θ value	6.88961 (rank : 322)	NC score	0.311890 (rank : 202)
Query Neighborhood Hits	353	Target Neighborhood Hits	1289	Shared Neighborhood Hits	263
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

APBA2_MOUSE
θ value	6.88961 (rank : 323)	NC score	0.006040 (rank : 453)
Query Neighborhood Hits	353	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

ARHGB_HUMAN
θ value	6.88961 (rank : 324)	NC score	0.005608 (rank : 454)
Query Neighborhood Hits	353	Target Neighborhood Hits	375	Shared Neighborhood Hits	13
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ASZ1_MOUSE
θ value	6.88961 (rank : 325)	NC score	0.349532 (rank : 155)
Query Neighborhood Hits	353	Target Neighborhood Hits	319	Shared Neighborhood Hits	226
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

CB017_MOUSE
θ value	6.88961 (rank : 326)	NC score	0.011479 (rank : 445)
Query Neighborhood Hits	353	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q6NS82, Q3TA48, Q8BSD3, Q8CHY1, Q8R0Q3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17 homolog.

COBA1_HUMAN
θ value	6.88961 (rank : 327)	NC score	0.007772 (rank : 450)
Query Neighborhood Hits	353	Target Neighborhood Hits	491	Shared Neighborhood Hits	23
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CYH2_HUMAN
θ value	6.88961 (rank : 328)	NC score	0.044997 (rank : 384)
Query Neighborhood Hits	353	Target Neighborhood Hits	175	Shared Neighborhood Hits	32
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

DCP1B_HUMAN
θ value	6.88961 (rank : 329)	NC score	0.009813 (rank : 448)
Query Neighborhood Hits	353	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

GAB2_MOUSE
θ value	6.88961 (rank : 330)	NC score	0.037011 (rank : 390)
Query Neighborhood Hits	353	Target Neighborhood Hits	220	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

HGFA_MOUSE
θ value	6.88961 (rank : 331)	NC score	0.000772 (rank : 461)
Query Neighborhood Hits	353	Target Neighborhood Hits	419	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ITCH_HUMAN
θ value	6.88961 (rank : 332)	NC score	0.005573 (rank : 455)
Query Neighborhood Hits	353	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

MYO5C_HUMAN
θ value	6.88961 (rank : 333)	NC score	0.027280 (rank : 427)
Query Neighborhood Hits	353	Target Neighborhood Hits	1206	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NIN_HUMAN
θ value	6.88961 (rank : 334)	NC score	0.026403 (rank : 431)
Query Neighborhood Hits	353	Target Neighborhood Hits	1416	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

POT22_HUMAN
θ value	6.88961 (rank : 335)	NC score	0.301518 (rank : 214)
Query Neighborhood Hits	353	Target Neighborhood Hits	266	Shared Neighborhood Hits	216
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

PP16B_MOUSE
θ value	6.88961 (rank : 336)	NC score	0.361708 (rank : 135)
Query Neighborhood Hits	353	Target Neighborhood Hits	302	Shared Neighborhood Hits	225
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

SRRM2_HUMAN
θ value	6.88961 (rank : 337)	NC score	0.039870 (rank : 388)
Query Neighborhood Hits	353	Target Neighborhood Hits	1296	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRPV5_MOUSE
θ value	6.88961 (rank : 338)	NC score	0.184821 (rank : 282)
Query Neighborhood Hits	353	Target Neighborhood Hits	278	Shared Neighborhood Hits	202
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

ZN750_MOUSE
θ value	6.88961 (rank : 339)	NC score	0.021038 (rank : 437)
Query Neighborhood Hits	353	Target Neighborhood Hits	346	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

AN13C_HUMAN
θ value	8.99809 (rank : 340)	NC score	0.249187 (rank : 245)
Query Neighborhood Hits	353	Target Neighborhood Hits	241	Shared Neighborhood Hits	203
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ANR38_MOUSE
θ value	8.99809 (rank : 341)	NC score	0.258799 (rank : 241)
Query Neighborhood Hits	353	Target Neighborhood Hits	512	Shared Neighborhood Hits	218
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ASB3_MOUSE
θ value	8.99809 (rank : 342)	NC score	0.377304 (rank : 111)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	225
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

CT2NL_MOUSE
θ value	8.99809 (rank : 343)	NC score	0.033103 (rank : 403)
Query Neighborhood Hits	353	Target Neighborhood Hits	902	Shared Neighborhood Hits	59
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CYH2_MOUSE
θ value	8.99809 (rank : 344)	NC score	0.044594 (rank : 385)
Query Neighborhood Hits	353	Target Neighborhood Hits	171	Shared Neighborhood Hits	32
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

FOG1_MOUSE
θ value	8.99809 (rank : 345)	NC score	0.000809 (rank : 460)
Query Neighborhood Hits	353	Target Neighborhood Hits	1237	Shared Neighborhood Hits	38
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GOGA1_MOUSE
θ value	8.99809 (rank : 346)	NC score	0.023888 (rank : 434)
Query Neighborhood Hits	353	Target Neighborhood Hits	994	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GP123_HUMAN
θ value	8.99809 (rank : 347)	NC score	0.004184 (rank : 458)
Query Neighborhood Hits	353	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

HUWE1_HUMAN
θ value	8.99809 (rank : 348)	NC score	0.010542 (rank : 446)
Query Neighborhood Hits	353	Target Neighborhood Hits	443	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HXB1_HUMAN
θ value	8.99809 (rank : 349)	NC score	-0.004149 (rank : 467)
Query Neighborhood Hits	353	Target Neighborhood Hits	356	Shared Neighborhood Hits	4
SwissProt Accessions	P14653	Gene names	HOXB1, HOX2I
Domain Architecture
Description	Homeobox protein Hox-B1 (Hox-2I).

PRTN3_HUMAN
θ value	8.99809 (rank : 350)	NC score	-0.002509 (rank : 464)
Query Neighborhood Hits	353	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P24158, P15637, P18078, Q6LBM7, Q9UQD8	Gene names	PRTN3, MBN
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Leukocyte proteinase 3) (PR-3) (PR3) (AGP7) (Wegener autoantigen) (P29) (C-ANCA antigen) (Neutrophil proteinase 4) (NP-4).

SEZ6L_HUMAN
θ value	8.99809 (rank : 351)	NC score	0.004302 (rank : 457)
Query Neighborhood Hits	353	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

TMPS4_MOUSE
θ value	8.99809 (rank : 352)	NC score	-0.003068 (rank : 466)
Query Neighborhood Hits	353	Target Neighborhood Hits	210	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

ZN418_HUMAN
θ value	8.99809 (rank : 353)	NC score	-0.009166 (rank : 468)
Query Neighborhood Hits	353	Target Neighborhood Hits	776	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TF45, Q670L5, Q96N18	Gene names	ZNF418, KIAA1956
Domain Architecture
Description	Zinc finger protein 418.

3BP1_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.051604 (rank : 374)
Query Neighborhood Hits	353	Target Neighborhood Hits	376	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ABTB1_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.089035 (rank : 322)
Query Neighborhood Hits	353	Target Neighborhood Hits	325	Shared Neighborhood Hits	131
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ABTB1_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.103158 (rank : 317)
Query Neighborhood Hits	353	Target Neighborhood Hits	349	Shared Neighborhood Hits	143
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

ABTB2_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.218142 (rank : 263)
Query Neighborhood Hits	353	Target Neighborhood Hits	391	Shared Neighborhood Hits	196
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ABTB2_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.211319 (rank : 264)
Query Neighborhood Hits	353	Target Neighborhood Hits	414	Shared Neighborhood Hits	196
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

AN13A_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.191765 (rank : 278)
Query Neighborhood Hits	353	Target Neighborhood Hits	243	Shared Neighborhood Hits	187
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

AN13A_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.181057 (rank : 283)
Query Neighborhood Hits	353	Target Neighborhood Hits	226	Shared Neighborhood Hits	185
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

AN13C_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.243970 (rank : 251)
Query Neighborhood Hits	353	Target Neighborhood Hits	242	Shared Neighborhood Hits	199
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN36A_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.344688 (rank : 163)
Query Neighborhood Hits	353	Target Neighborhood Hits	271	Shared Neighborhood Hits	220
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

AN36B_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.347973 (rank : 158)
Query Neighborhood Hits	353	Target Neighborhood Hits	294	Shared Neighborhood Hits	223
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANKF1_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.054749 (rank : 358)
Query Neighborhood Hits	353	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKR9_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.132909 (rank : 307)
Query Neighborhood Hits	353	Target Neighborhood Hits	99	Shared Neighborhood Hits	90
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKS3_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.343735 (rank : 166)
Query Neighborhood Hits	353	Target Neighborhood Hits	355	Shared Neighborhood Hits	224
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANKY1_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.200380 (rank : 268)
Query Neighborhood Hits	353	Target Neighborhood Hits	248	Shared Neighborhood Hits	173
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ANKZ1_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.121456 (rank : 312)
Query Neighborhood Hits	353	Target Neighborhood Hits	236	Shared Neighborhood Hits	139
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ANKZ1_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.130089 (rank : 309)
Query Neighborhood Hits	353	Target Neighborhood Hits	208	Shared Neighborhood Hits	130
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

ANR32_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.305261 (rank : 208)
Query Neighborhood Hits	353	Target Neighborhood Hits	270	Shared Neighborhood Hits	212
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR32_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.304277 (rank : 212)
Query Neighborhood Hits	353	Target Neighborhood Hits	285	Shared Neighborhood Hits	212
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR33_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.302743 (rank : 213)
Query Neighborhood Hits	353	Target Neighborhood Hits	225	Shared Neighborhood Hits	195
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR40_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.227585 (rank : 260)
Query Neighborhood Hits	353	Target Neighborhood Hits	224	Shared Neighborhood Hits	170
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.224684 (rank : 261)
Query Neighborhood Hits	353	Target Neighborhood Hits	228	Shared Neighborhood Hits	173
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR43_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.274003 (rank : 235)
Query Neighborhood Hits	353	Target Neighborhood Hits	209	Shared Neighborhood Hits	179
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR43_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.267864 (rank : 238)
Query Neighborhood Hits	353	Target Neighborhood Hits	214	Shared Neighborhood Hits	181
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR46_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.412506 (rank : 46)
Query Neighborhood Hits	353	Target Neighborhood Hits	281	Shared Neighborhood Hits	220
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR46_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.397519 (rank : 69)
Query Neighborhood Hits	353	Target Neighborhood Hits	274	Shared Neighborhood Hits	217
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR49_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.366409 (rank : 132)
Query Neighborhood Hits	353	Target Neighborhood Hits	285	Shared Neighborhood Hits	221
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ASB11_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.340703 (rank : 176)
Query Neighborhood Hits	353	Target Neighborhood Hits	271	Shared Neighborhood Hits	216
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB11_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.346934 (rank : 161)
Query Neighborhood Hits	353	Target Neighborhood Hits	271	Shared Neighborhood Hits	216
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB12_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.337083 (rank : 183)
Query Neighborhood Hits	353	Target Neighborhood Hits	263	Shared Neighborhood Hits	216
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB14_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.191394 (rank : 279)
Query Neighborhood Hits	353	Target Neighborhood Hits	187	Shared Neighborhood Hits	155
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB3_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.371989 (rank : 125)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	224
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB5_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.331065 (rank : 187)
Query Neighborhood Hits	353	Target Neighborhood Hits	266	Shared Neighborhood Hits	212
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB9_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.328873 (rank : 188)
Query Neighborhood Hits	353	Target Neighborhood Hits	257	Shared Neighborhood Hits	203
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASZ1_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.339584 (rank : 178)
Query Neighborhood Hits	353	Target Neighborhood Hits	341	Shared Neighborhood Hits	228
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

BAT4_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.113852 (rank : 314)
Query Neighborhood Hits	353	Target Neighborhood Hits	157	Shared Neighborhood Hits	96
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BAT4_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.112302 (rank : 315)
Query Neighborhood Hits	353	Target Neighborhood Hits	171	Shared Neighborhood Hits	107
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BCOR_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.282416 (rank : 230)
Query Neighborhood Hits	353	Target Neighborhood Hits	609	Shared Neighborhood Hits	234
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BCOR_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.288904 (rank : 225)
Query Neighborhood Hits	353	Target Neighborhood Hits	521	Shared Neighborhood Hits	230
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BCR_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.052493 (rank : 367)
Query Neighborhood Hits	353	Target Neighborhood Hits	204	Shared Neighborhood Hits	17
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CD2A1_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.255388 (rank : 243)
Query Neighborhood Hits	353	Target Neighborhood Hits	196	Shared Neighborhood Hits	163
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CD2A1_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.279079 (rank : 231)
Query Neighborhood Hits	353	Target Neighborhood Hits	206	Shared Neighborhood Hits	172
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CD2AP_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.051258 (rank : 376)
Query Neighborhood Hits	353	Target Neighborhood Hits	315	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CDN2B_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.240887 (rank : 253)
Query Neighborhood Hits	353	Target Neighborhood Hits	196	Shared Neighborhood Hits	164
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CDN2B_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.245303 (rank : 250)
Query Neighborhood Hits	353	Target Neighborhood Hits	201	Shared Neighborhood Hits	168
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CDN2D_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.359726 (rank : 137)
Query Neighborhood Hits	353	Target Neighborhood Hits	268	Shared Neighborhood Hits	215
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CDN2D_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.349035 (rank : 156)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	213
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CMTA1_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.077610 (rank : 328)
Query Neighborhood Hits	353	Target Neighborhood Hits	217	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CMTA2_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.062027 (rank : 341)
Query Neighborhood Hits	353	Target Neighborhood Hits	199	Shared Neighborhood Hits	83
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.057481 (rank : 353)
Query Neighborhood Hits	353	Target Neighborhood Hits	216	Shared Neighborhood Hits	71
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CT012_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.162794 (rank : 297)
Query Neighborhood Hits	353	Target Neighborhood Hits	205	Shared Neighborhood Hits	145
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

CT012_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.180872 (rank : 285)
Query Neighborhood Hits	353	Target Neighborhood Hits	229	Shared Neighborhood Hits	151
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

DGKD_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.051799 (rank : 372)
Query Neighborhood Hits	353	Target Neighborhood Hits	231	Shared Neighborhood Hits	35
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.059913 (rank : 348)
Query Neighborhood Hits	353	Target Neighborhood Hits	255	Shared Neighborhood Hits	44
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DGKZ_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.148151 (rank : 302)
Query Neighborhood Hits	353	Target Neighborhood Hits	542	Shared Neighborhood Hits	176
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DP13A_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.199359 (rank : 269)
Query Neighborhood Hits	353	Target Neighborhood Hits	107	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.195684 (rank : 275)
Query Neighborhood Hits	353	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

GLSK_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.175843 (rank : 288)
Query Neighborhood Hits	353	Target Neighborhood Hits	204	Shared Neighborhood Hits	159
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

GLSL_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.198646 (rank : 273)
Query Neighborhood Hits	353	Target Neighborhood Hits	211	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GLSL_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.191228 (rank : 280)
Query Neighborhood Hits	353	Target Neighborhood Hits	212	Shared Neighborhood Hits	162
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GMIP_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.053074 (rank : 364)
Query Neighborhood Hits	353	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.054716 (rank : 359)
Query Neighborhood Hits	353	Target Neighborhood Hits	202	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GRLF1_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.051034 (rank : 378)
Query Neighborhood Hits	353	Target Neighborhood Hits	167	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

IKBL_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.136810 (rank : 305)
Query Neighborhood Hits	353	Target Neighborhood Hits	168	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.132887 (rank : 308)
Query Neighborhood Hits	353	Target Neighborhood Hits	196	Shared Neighborhood Hits	123
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

KRIT1_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.252300 (rank : 244)
Query Neighborhood Hits	353	Target Neighborhood Hits	258	Shared Neighborhood Hits	186
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.255723 (rank : 242)
Query Neighborhood Hits	353	Target Neighborhood Hits	258	Shared Neighborhood Hits	192
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

MYO9B_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.053960 (rank : 362)
Query Neighborhood Hits	353	Target Neighborhood Hits	641	Shared Neighborhood Hits	58
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.051241 (rank : 377)
Query Neighborhood Hits	353	Target Neighborhood Hits	311	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

NCF2_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.052746 (rank : 365)
Query Neighborhood Hits	353	Target Neighborhood Hits	229	Shared Neighborhood Hits	12
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

OPHN1_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.162271 (rank : 298)
Query Neighborhood Hits	353	Target Neighborhood Hits	161	Shared Neighborhood Hits	20
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OSBP2_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.060987 (rank : 345)
Query Neighborhood Hits	353	Target Neighborhood Hits	154	Shared Neighborhood Hits	29
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP2_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.059766 (rank : 350)
Query Neighborhood Hits	353	Target Neighborhood Hits	150	Shared Neighborhood Hits	33
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSTF1_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.283915 (rank : 228)
Query Neighborhood Hits	353	Target Neighborhood Hits	466	Shared Neighborhood Hits	212
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

PKHA2_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.094546 (rank : 319)
Query Neighborhood Hits	353	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.099034 (rank : 318)
Query Neighborhood Hits	353	Target Neighborhood Hits	116	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA4_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.071386 (rank : 335)
Query Neighborhood Hits	353	Target Neighborhood Hits	283	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.071724 (rank : 334)
Query Neighborhood Hits	353	Target Neighborhood Hits	202	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

RBP1_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.061669 (rank : 343)
Query Neighborhood Hits	353	Target Neighborhood Hits	521	Shared Neighborhood Hits	47
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RBP1_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.063647 (rank : 339)
Query Neighborhood Hits	353	Target Neighborhood Hits	493	Shared Neighborhood Hits	48
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RGAP1_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.056961 (rank : 354)
Query Neighborhood Hits	353	Target Neighborhood Hits	189	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.055817 (rank : 357)
Query Neighborhood Hits	353	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG05_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.053642 (rank : 363)
Query Neighborhood Hits	353	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.053976 (rank : 361)
Query Neighborhood Hits	353	Target Neighborhood Hits	165	Shared Neighborhood Hits	17
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG06_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.052179 (rank : 369)
Query Neighborhood Hits	353	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.051669 (rank : 373)
Query Neighborhood Hits	353	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG09_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.068673 (rank : 337)
Query Neighborhood Hits	353	Target Neighborhood Hits	186	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG12_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.051548 (rank : 375)
Query Neighborhood Hits	353	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG18_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.052139 (rank : 370)
Query Neighborhood Hits	353	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG25_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.058392 (rank : 352)
Query Neighborhood Hits	353	Target Neighborhood Hits	550	Shared Neighborhood Hits	65
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.060667 (rank : 347)
Query Neighborhood Hits	353	Target Neighborhood Hits	492	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RN5A_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.334295 (rank : 185)
Query Neighborhood Hits	353	Target Neighborhood Hits	608	Shared Neighborhood Hits	227
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

RN5A_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.309331 (rank : 204)
Query Neighborhood Hits	353	Target Neighborhood Hits	899	Shared Neighborhood Hits	225
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

RSNL2_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.084111 (rank : 326)
Query Neighborhood Hits	353	Target Neighborhood Hits	136	Shared Neighborhood Hits	103
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSNL2_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.072879 (rank : 329)
Query Neighborhood Hits	353	Target Neighborhood Hits	129	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

SH3G1_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.055938 (rank : 356)
Query Neighborhood Hits	353	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G1_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.056346 (rank : 355)
Query Neighborhood Hits	353	Target Neighborhood Hits	291	Shared Neighborhood Hits	20
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G2_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.050787 (rank : 379)
Query Neighborhood Hits	353	Target Neighborhood Hits	319	Shared Neighborhood Hits	25
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3K1_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.059729 (rank : 351)
Query Neighborhood Hits	353	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.059890 (rank : 349)
Query Neighborhood Hits	353	Target Neighborhood Hits	332	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

STAM2_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.054218 (rank : 360)
Query Neighborhood Hits	353	Target Neighborhood Hits	285	Shared Neighborhood Hits	18
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

SWP70_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.052382 (rank : 368)
Query Neighborhood Hits	353	Target Neighborhood Hits	973	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.052016 (rank : 371)
Query Neighborhood Hits	353	Target Neighborhood Hits	1097	Shared Neighborhood Hits	83
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TCGAP_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.072067 (rank : 332)
Query Neighborhood Hits	353	Target Neighborhood Hits	872	Shared Neighborhood Hits	44
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.060931 (rank : 346)
Query Neighborhood Hits	353	Target Neighborhood Hits	409	Shared Neighborhood Hits	30
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TEX14_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.160747 (rank : 300)
Query Neighborhood Hits	353	Target Neighborhood Hits	1103	Shared Neighborhood Hits	224
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.163287 (rank : 296)
Query Neighborhood Hits	353	Target Neighborhood Hits	1333	Shared Neighborhood Hits	243
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TRPV1_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.088140 (rank : 323)
Query Neighborhood Hits	353	Target Neighborhood Hits	184	Shared Neighborhood Hits	126
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV1_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.090849 (rank : 320)
Query Neighborhood Hits	353	Target Neighborhood Hits	189	Shared Neighborhood Hits	128
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV2_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.067111 (rank : 338)
Query Neighborhood Hits	353	Target Neighborhood Hits	130	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TRPV2_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.050771 (rank : 380)
Query Neighborhood Hits	353	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV3_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.072634 (rank : 331)
Query Neighborhood Hits	353	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.071902 (rank : 333)
Query Neighborhood Hits	353	Target Neighborhood Hits	188	Shared Neighborhood Hits	110
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV5_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.163764 (rank : 295)
Query Neighborhood Hits	353	Target Neighborhood Hits	261	Shared Neighborhood Hits	179
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV6_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.162158 (rank : 299)
Query Neighborhood Hits	353	Target Neighborhood Hits	262	Shared Neighborhood Hits	181
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV6_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.199212 (rank : 270)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	203
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

Hits sorted by NC score

DDFL1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	353	Target Neighborhood Hits	353	Shared Neighborhood Hits	353
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
NC score	0.971896 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	353	Target Neighborhood Hits	324	Shared Neighborhood Hits	261
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DDEF2_HUMAN
NC score	0.899353 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	353	Target Neighborhood Hits	599	Shared Neighborhood Hits	263
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.893967 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	353	Target Neighborhood Hits	625	Shared Neighborhood Hits	259
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF1_MOUSE
NC score	0.878283 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	353	Target Neighborhood Hits	592	Shared Neighborhood Hits	222
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

CENB5_HUMAN
NC score	0.806429 (rank : 6)	θ value	1.41672e-45 (rank : 6)
Query Neighborhood Hits	353	Target Neighborhood Hits	395	Shared Neighborhood Hits	264
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB1_HUMAN
NC score	0.805267 (rank : 7)	θ value	1.2411e-41 (rank : 8)
Query Neighborhood Hits	353	Target Neighborhood Hits	383	Shared Neighborhood Hits	252
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
NC score	0.792787 (rank : 8)	θ value	2.67181e-44 (rank : 7)
Query Neighborhood Hits	353	Target Neighborhood Hits	425	Shared Neighborhood Hits	258
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENG1_MOUSE
NC score	0.701548 (rank : 9)	θ value	3.74554e-30 (rank : 9)
Query Neighborhood Hits	353	Target Neighborhood Hits	531	Shared Neighborhood Hits	231
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG1_HUMAN
NC score	0.694797 (rank : 10)	θ value	1.4233e-29 (rank : 10)
Query Neighborhood Hits	353	Target Neighborhood Hits	544	Shared Neighborhood Hits	231
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG3_MOUSE
NC score	0.679336 (rank : 11)	θ value	1.80048e-24 (rank : 13)
Query Neighborhood Hits	353	Target Neighborhood Hits	467	Shared Neighborhood Hits	222
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_HUMAN
NC score	0.678632 (rank : 12)	θ value	2.35151e-24 (rank : 14)
Query Neighborhood Hits	353	Target Neighborhood Hits	455	Shared Neighborhood Hits	221
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG2_MOUSE
NC score	0.671417 (rank : 13)	θ value	1.47289e-26 (rank : 11)
Query Neighborhood Hits	353	Target Neighborhood Hits	463	Shared Neighborhood Hits	235
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENG2_HUMAN
NC score	0.669390 (rank : 14)	θ value	1.92365e-26 (rank : 12)
Query Neighborhood Hits	353	Target Neighborhood Hits	471	Shared Neighborhood Hits	236
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENA1_HUMAN
NC score	0.665315 (rank : 15)	θ value	1.68911e-14 (rank : 21)
Query Neighborhood Hits	353	Target Neighborhood Hits	87	Shared Neighborhood Hits	52
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

SMAP1_MOUSE
NC score	0.664287 (rank : 16)	θ value	4.44505e-15 (rank : 19)
Query Neighborhood Hits	353	Target Neighborhood Hits	120	Shared Neighborhood Hits	42
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

GIT2_MOUSE
NC score	0.663809 (rank : 17)	θ value	2.52405e-10 (rank : 30)
Query Neighborhood Hits	353	Target Neighborhood Hits	323	Shared Neighborhood Hits	233
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

SMAP1_HUMAN
NC score	0.661978 (rank : 18)	θ value	3.76295e-14 (rank : 22)
Query Neighborhood Hits	353	Target Neighborhood Hits	98	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
NC score	0.661237 (rank : 19)	θ value	7.09661e-13 (rank : 23)
Query Neighborhood Hits	353	Target Neighborhood Hits	74	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
NC score	0.660187 (rank : 20)	θ value	7.09661e-13 (rank : 24)
Query Neighborhood Hits	353	Target Neighborhood Hits	70	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

ARFG1_MOUSE
NC score	0.654754 (rank : 21)	θ value	3.52202e-12 (rank : 25)
Query Neighborhood Hits	353	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

GIT2_HUMAN
NC score	0.653417 (rank : 22)	θ value	2.52405e-10 (rank : 29)
Query Neighborhood Hits	353	Target Neighborhood Hits	381	Shared Neighborhood Hits	245
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

GIT1_HUMAN
NC score	0.642805 (rank : 23)	θ value	1.25267e-09 (rank : 31)
Query Neighborhood Hits	353	Target Neighborhood Hits	336	Shared Neighborhood Hits	231
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
NC score	0.642469 (rank : 24)	θ value	1.25267e-09 (rank : 32)
Query Neighborhood Hits	353	Target Neighborhood Hits	341	Shared Neighborhood Hits	234
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

ARFG1_HUMAN
NC score	0.639608 (rank : 25)	θ value	6.00763e-12 (rank : 27)
Query Neighborhood Hits	353	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

CENA2_MOUSE
NC score	0.634837 (rank : 26)	θ value	4.59992e-12 (rank : 26)
Query Neighborhood Hits	353	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CENA2_HUMAN
NC score	0.624843 (rank : 27)	θ value	7.84624e-12 (rank : 28)
Query Neighborhood Hits	353	Target Neighborhood Hits	83	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

ARFG3_HUMAN
NC score	0.619298 (rank : 28)	θ value	2.79066e-09 (rank : 34)
Query Neighborhood Hits	353	Target Neighborhood Hits	56	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
NC score	0.615977 (rank : 29)	θ value	2.13673e-09 (rank : 33)
Query Neighborhood Hits	353	Target Neighborhood Hits	80	Shared Neighborhood Hits	38
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

CEND1_HUMAN
NC score	0.534002 (rank : 30)	θ value	3.40345e-15 (rank : 18)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND1_MOUSE
NC score	0.531905 (rank : 31)	θ value	7.58209e-15 (rank : 20)
Query Neighborhood Hits	353	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND2_HUMAN
NC score	0.524224 (rank : 32)	θ value	4.29542e-18 (rank : 16)
Query Neighborhood Hits	353	Target Neighborhood Hits	166	Shared Neighborhood Hits	61
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CEND3_HUMAN
NC score	0.515320 (rank : 33)	θ value	8.65492e-19 (rank : 15)
Query Neighborhood Hits	353	Target Neighborhood Hits	275	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CEND3_MOUSE
NC score	0.508239 (rank : 34)	θ value	2.7842e-17 (rank : 17)
Query Neighborhood Hits	353	Target Neighborhood Hits	228	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CT086_HUMAN
NC score	0.460661 (rank : 35)	θ value	0.00298849 (rank : 89)
Query Neighborhood Hits	353	Target Neighborhood Hits	277	Shared Neighborhood Hits	219
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

ANR37_MOUSE
NC score	0.445810 (rank : 36)	θ value	0.00035302 (rank : 56)
Query Neighborhood Hits	353	Target Neighborhood Hits	237	Shared Neighborhood Hits	205
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANR37_HUMAN
NC score	0.434510 (rank : 37)	θ value	0.00175202 (rank : 75)
Query Neighborhood Hits	353	Target Neighborhood Hits	247	Shared Neighborhood Hits	211
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ANR39_HUMAN
NC score	0.429732 (rank : 38)	θ value	7.1131e-05 (rank : 45)
Query Neighborhood Hits	353	Target Neighborhood Hits	285	Shared Neighborhood Hits	224
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR39_MOUSE
NC score	0.428254 (rank : 39)	θ value	0.000158464 (rank : 48)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	223
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANKR6_HUMAN
NC score	0.427706 (rank : 40)	θ value	7.59969e-07 (rank : 36)
Query Neighborhood Hits	353	Target Neighborhood Hits	439	Shared Neighborhood Hits	233
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR22_HUMAN
NC score	0.424090 (rank : 41)	θ value	0.00020696 (rank : 49)
Query Neighborhood Hits	353	Target Neighborhood Hits	243	Shared Neighborhood Hits	207
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR10_HUMAN
NC score	0.419253 (rank : 42)	θ value	2.44474e-05 (rank : 39)
Query Neighborhood Hits	353	Target Neighborhood Hits	289	Shared Neighborhood Hits	218
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR42_HUMAN
NC score	0.414937 (rank : 43)	θ value	0.000270298 (rank : 52)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	224
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR10_MOUSE
NC score	0.414543 (rank : 44)	θ value	0.00134147 (rank : 70)
Query Neighborhood Hits	353	Target Neighborhood Hits	273	Shared Neighborhood Hits	217
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

GABP3_MOUSE
NC score	0.413754 (rank : 45)	θ value	0.00390308 (rank : 97)
Query Neighborhood Hits	353	Target Neighborhood Hits	330	Shared Neighborhood Hits	226
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ANR46_HUMAN
NC score	0.412506 (rank : 46)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	353	Target Neighborhood Hits	281	Shared Neighborhood Hits	220
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR42_MOUSE
NC score	0.411840 (rank : 47)	θ value	0.00228821 (rank : 81)
Query Neighborhood Hits	353	Target Neighborhood Hits	334	Shared Neighborhood Hits	229
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANS4B_MOUSE
NC score	0.410926 (rank : 48)	θ value	0.00020696 (rank : 50)
Query Neighborhood Hits	353	Target Neighborhood Hits	294	Shared Neighborhood Hits	213
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANR23_HUMAN
NC score	0.410115 (rank : 49)	θ value	0.000270298 (rank : 51)
Query Neighborhood Hits	353	Target Neighborhood Hits	291	Shared Neighborhood Hits	226
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

GABP2_MOUSE
NC score	0.409700 (rank : 50)	θ value	0.000461057 (rank : 62)
Query Neighborhood Hits	353	Target Neighborhood Hits	429	Shared Neighborhood Hits	233
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

GABP2_HUMAN
NC score	0.409479 (rank : 51)	θ value	0.00035302 (rank : 59)
Query Neighborhood Hits	353	Target Neighborhood Hits	454	Shared Neighborhood Hits	235
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ANS4B_HUMAN
NC score	0.409058 (rank : 52)	θ value	0.000786445 (rank : 66)
Query Neighborhood Hits	353	Target Neighborhood Hits	289	Shared Neighborhood Hits	215
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

PSD10_HUMAN
NC score	0.406466 (rank : 53)	θ value	0.0431538 (rank : 132)
Query Neighborhood Hits	353	Target Neighborhood Hits	301	Shared Neighborhood Hits	226
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR23_MOUSE
NC score	0.406214 (rank : 54)	θ value	2.44474e-05 (rank : 40)
Query Neighborhood Hits	353	Target Neighborhood Hits	296	Shared Neighborhood Hits	225
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANK1_HUMAN
NC score	0.404324 (rank : 55)	θ value	3.19293e-05 (rank : 41)
Query Neighborhood Hits	353	Target Neighborhood Hits	416	Shared Neighborhood Hits	227
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANKR1_MOUSE
NC score	0.404135 (rank : 56)	θ value	0.00228821 (rank : 79)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	225
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

PSD10_MOUSE
NC score	0.404002 (rank : 57)	θ value	0.0563607 (rank : 147)
Query Neighborhood Hits	353	Target Neighborhood Hits	293	Shared Neighborhood Hits	225
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANK1_MOUSE
NC score	0.402957 (rank : 58)	θ value	0.000461057 (rank : 60)
Query Neighborhood Hits	353	Target Neighborhood Hits	430	Shared Neighborhood Hits	230
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

PA2G6_MOUSE
NC score	0.401889 (rank : 59)	θ value	9.29e-05 (rank : 46)
Query Neighborhood Hits	353	Target Neighborhood Hits	293	Shared Neighborhood Hits	226
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANKR1_HUMAN
NC score	0.401081 (rank : 60)	θ value	0.00298849 (rank : 87)
Query Neighborhood Hits	353	Target Neighborhood Hits	308	Shared Neighborhood Hits	227
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

MYPT1_MOUSE
NC score	0.401049 (rank : 61)	θ value	0.00228821 (rank : 83)
Query Neighborhood Hits	353	Target Neighborhood Hits	539	Shared Neighborhood Hits	232
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

USH1G_MOUSE
NC score	0.400461 (rank : 62)	θ value	0.000270298 (rank : 55)
Query Neighborhood Hits	353	Target Neighborhood Hits	271	Shared Neighborhood Hits	217
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

USH1G_HUMAN
NC score	0.400247 (rank : 63)	θ value	0.000270298 (rank : 54)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	217
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

ANR41_HUMAN
NC score	0.399371 (rank : 64)	θ value	0.0113563 (rank : 108)
Query Neighborhood Hits	353	Target Neighborhood Hits	332	Shared Neighborhood Hits	212
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

IKBB_MOUSE
NC score	0.399248 (rank : 65)	θ value	0.0563607 (rank : 144)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	222
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

NUPL_HUMAN
NC score	0.398982 (rank : 66)	θ value	0.0113563 (rank : 109)
Query Neighborhood Hits	353	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

ANKR2_HUMAN
NC score	0.398949 (rank : 67)	θ value	0.00228821 (rank : 80)
Query Neighborhood Hits	353	Target Neighborhood Hits	321	Shared Neighborhood Hits	231
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR52_MOUSE
NC score	0.398386 (rank : 68)	θ value	0.00390308 (rank : 94)
Query Neighborhood Hits	353	Target Neighborhood Hits	318	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR46_MOUSE
NC score	0.397519 (rank : 69)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	353	Target Neighborhood Hits	274	Shared Neighborhood Hits	217
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANKR2_MOUSE
NC score	0.397431 (rank : 70)	θ value	0.0113563 (rank : 107)
Query Neighborhood Hits	353	Target Neighborhood Hits	312	Shared Neighborhood Hits	228
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR52_HUMAN
NC score	0.397140 (rank : 71)	θ value	0.00390308 (rank : 93)
Query Neighborhood Hits	353	Target Neighborhood Hits	322	Shared Neighborhood Hits	226
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR44_HUMAN
NC score	0.396992 (rank : 72)	θ value	0.00035302 (rank : 57)
Query Neighborhood Hits	353	Target Neighborhood Hits	318	Shared Neighborhood Hits	226
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ASB8_MOUSE
NC score	0.395374 (rank : 73)	θ value	0.0252991 (rank : 121)
Query Neighborhood Hits	353	Target Neighborhood Hits	293	Shared Neighborhood Hits	223
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_HUMAN
NC score	0.395244 (rank : 74)	θ value	0.0252991 (rank : 120)
Query Neighborhood Hits	353	Target Neighborhood Hits	294	Shared Neighborhood Hits	223
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

PA2G6_HUMAN
NC score	0.395130 (rank : 75)	θ value	0.00869519 (rank : 105)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	224
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANR28_MOUSE
NC score	0.394728 (rank : 76)	θ value	0.00869519 (rank : 104)
Query Neighborhood Hits	353	Target Neighborhood Hits	314	Shared Neighborhood Hits	227
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

NUPL_MOUSE
NC score	0.394571 (rank : 77)	θ value	0.0113563 (rank : 110)
Query Neighborhood Hits	353	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

MYPT1_HUMAN
NC score	0.394511 (rank : 78)	θ value	0.00228821 (rank : 82)
Query Neighborhood Hits	353	Target Neighborhood Hits	723	Shared Neighborhood Hits	247
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ANK3_HUMAN
NC score	0.394120 (rank : 79)	θ value	2.44474e-05 (rank : 38)
Query Neighborhood Hits	353	Target Neighborhood Hits	853	Shared Neighborhood Hits	243
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

TNKS1_HUMAN
NC score	0.393913 (rank : 80)	θ value	0.0193708 (rank : 119)
Query Neighborhood Hits	353	Target Neighborhood Hits	477	Shared Neighborhood Hits	238
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANR28_HUMAN
NC score	0.393790 (rank : 81)	θ value	0.00665767 (rank : 100)
Query Neighborhood Hits	353	Target Neighborhood Hits	314	Shared Neighborhood Hits	227
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

CSKI2_HUMAN
NC score	0.390505 (rank : 82)	θ value	0.00134147 (rank : 73)
Query Neighborhood Hits	353	Target Neighborhood Hits	747	Shared Neighborhood Hits	251
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB10_MOUSE
NC score	0.389983 (rank : 83)	θ value	0.0961366 (rank : 153)
Query Neighborhood Hits	353	Target Neighborhood Hits	301	Shared Neighborhood Hits	226
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

TNKS2_HUMAN
NC score	0.389844 (rank : 84)	θ value	0.00298849 (rank : 92)
Query Neighborhood Hits	353	Target Neighborhood Hits	361	Shared Neighborhood Hits	230
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

CSKI2_MOUSE
NC score	0.389814 (rank : 85)	θ value	0.00134147 (rank : 74)
Query Neighborhood Hits	353	Target Neighborhood Hits	812	Shared Neighborhood Hits	249
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANR50_HUMAN
NC score	0.389438 (rank : 86)	θ value	0.00509761 (rank : 98)
Query Neighborhood Hits	353	Target Neighborhood Hits	361	Shared Neighborhood Hits	226
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

MTPN_MOUSE
NC score	0.389407 (rank : 87)	θ value	0.62314 (rank : 213)
Query Neighborhood Hits	353	Target Neighborhood Hits	269	Shared Neighborhood Hits	217
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

ASB10_HUMAN
NC score	0.389277 (rank : 88)	θ value	3.0926 (rank : 274)
Query Neighborhood Hits	353	Target Neighborhood Hits	291	Shared Neighborhood Hits	225
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

MYPT2_HUMAN
NC score	0.388718 (rank : 89)	θ value	0.00102713 (rank : 69)
Query Neighborhood Hits	353	Target Neighborhood Hits	707	Shared Neighborhood Hits	250
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ASB16_HUMAN
NC score	0.388113 (rank : 90)	θ value	0.00134147 (rank : 72)
Query Neighborhood Hits	353	Target Neighborhood Hits	286	Shared Neighborhood Hits	224
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

BCL3_HUMAN
NC score	0.387375 (rank : 91)	θ value	0.0563607 (rank : 140)
Query Neighborhood Hits	353	Target Neighborhood Hits	324	Shared Neighborhood Hits	226
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ASB16_MOUSE
NC score	0.385420 (rank : 92)	θ value	0.000461057 (rank : 61)
Query Neighborhood Hits	353	Target Neighborhood Hits	306	Shared Neighborhood Hits	225
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANR29_HUMAN
NC score	0.385036 (rank : 93)	θ value	0.21417 (rank : 179)
Query Neighborhood Hits	353	Target Neighborhood Hits	294	Shared Neighborhood Hits	223
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

BCL3_MOUSE
NC score	0.384774 (rank : 94)	θ value	0.163984 (rank : 174)
Query Neighborhood Hits	353	Target Neighborhood Hits	388	Shared Neighborhood Hits	230
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

MIB2_HUMAN
NC score	0.384619 (rank : 95)	θ value	1.87187e-05 (rank : 37)
Query Neighborhood Hits	353	Target Neighborhood Hits	438	Shared Neighborhood Hits	227
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ASB7_MOUSE
NC score	0.383824 (rank : 96)	θ value	0.00390308 (rank : 96)
Query Neighborhood Hits	353	Target Neighborhood Hits	296	Shared Neighborhood Hits	225
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_HUMAN
NC score	0.383642 (rank : 97)	θ value	0.00390308 (rank : 95)
Query Neighborhood Hits	353	Target Neighborhood Hits	296	Shared Neighborhood Hits	225
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB2_HUMAN
NC score	0.383449 (rank : 98)	θ value	0.0193708 (rank : 116)
Query Neighborhood Hits	353	Target Neighborhood Hits	309	Shared Neighborhood Hits	225
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

MTPN_HUMAN
NC score	0.382976 (rank : 99)	θ value	1.81305 (rank : 251)
Query Neighborhood Hits	353	Target Neighborhood Hits	269	Shared Neighborhood Hits	217
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

MIB2_MOUSE
NC score	0.381692 (rank : 100)	θ value	0.000121331 (rank : 47)
Query Neighborhood Hits	353	Target Neighborhood Hits	409	Shared Neighborhood Hits	226
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

FANK1_MOUSE
NC score	0.381489 (rank : 101)	θ value	0.0563607 (rank : 142)
Query Neighborhood Hits	353	Target Neighborhood Hits	325	Shared Neighborhood Hits	223
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

IKBE_MOUSE
NC score	0.381410 (rank : 102)	θ value	0.00509761 (rank : 99)
Query Neighborhood Hits	353	Target Neighborhood Hits	308	Shared Neighborhood Hits	226
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

INVS_HUMAN
NC score	0.381161 (rank : 103)	θ value	0.0252991 (rank : 124)
Query Neighborhood Hits	353	Target Neighborhood Hits	455	Shared Neighborhood Hits	235
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

IKBB_HUMAN
NC score	0.381005 (rank : 104)	θ value	2.36792 (rank : 264)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	225
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

BARD1_HUMAN
NC score	0.379755 (rank : 105)	θ value	5.44631e-05 (rank : 43)
Query Neighborhood Hits	353	Target Neighborhood Hits	427	Shared Neighborhood Hits	223
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

INVS_MOUSE
NC score	0.379751 (rank : 106)	θ value	0.0330416 (rank : 128)
Query Neighborhood Hits	353	Target Neighborhood Hits	609	Shared Neighborhood Hits	234
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

FANK1_HUMAN
NC score	0.378145 (rank : 107)	θ value	0.0563607 (rank : 141)
Query Neighborhood Hits	353	Target Neighborhood Hits	326	Shared Neighborhood Hits	223
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

CSKI1_HUMAN
NC score	0.378042 (rank : 108)	θ value	0.00175202 (rank : 77)
Query Neighborhood Hits	353	Target Neighborhood Hits	997	Shared Neighborhood Hits	254
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ASB13_MOUSE
NC score	0.377639 (rank : 109)	θ value	0.0563607 (rank : 138)
Query Neighborhood Hits	353	Target Neighborhood Hits	293	Shared Neighborhood Hits	223
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_HUMAN
NC score	0.377549 (rank : 110)	θ value	0.0563607 (rank : 137)
Query Neighborhood Hits	353	Target Neighborhood Hits	293	Shared Neighborhood Hits	223
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB3_MOUSE
NC score	0.377304 (rank : 111)	θ value	8.99809 (rank : 342)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	225
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB2_MOUSE
NC score	0.376695 (rank : 112)	θ value	0.00175202 (rank : 76)
Query Neighborhood Hits	353	Target Neighborhood Hits	321	Shared Neighborhood Hits	223
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

CSKI1_MOUSE
NC score	0.376590 (rank : 113)	θ value	0.000602161 (rank : 65)
Query Neighborhood Hits	353	Target Neighborhood Hits	1031	Shared Neighborhood Hits	252
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANR49_HUMAN
NC score	0.375393 (rank : 114)	θ value	0.62314 (rank : 208)
Query Neighborhood Hits	353	Target Neighborhood Hits	282	Shared Neighborhood Hits	221
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ANRA2_HUMAN
NC score	0.375369 (rank : 115)	θ value	3.0926 (rank : 273)
Query Neighborhood Hits	353	Target Neighborhood Hits	288	Shared Neighborhood Hits	222
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANR35_HUMAN
NC score	0.375105 (rank : 116)	θ value	0.00298849 (rank : 88)
Query Neighborhood Hits	353	Target Neighborhood Hits	784	Shared Neighborhood Hits	252
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

MIB1_MOUSE
NC score	0.374760 (rank : 117)	θ value	0.00102713 (rank : 68)
Query Neighborhood Hits	353	Target Neighborhood Hits	471	Shared Neighborhood Hits	227
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MIB1_HUMAN
NC score	0.374697 (rank : 118)	θ value	0.00102713 (rank : 67)
Query Neighborhood Hits	353	Target Neighborhood Hits	470	Shared Neighborhood Hits	226
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

EHMT1_HUMAN
NC score	0.374655 (rank : 119)	θ value	1.99992e-07 (rank : 35)
Query Neighborhood Hits	353	Target Neighborhood Hits	417	Shared Neighborhood Hits	230
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ANK2_HUMAN
NC score	0.374172 (rank : 120)	θ value	4.1701e-05 (rank : 42)
Query Neighborhood Hits	353	Target Neighborhood Hits	1615	Shared Neighborhood Hits	262
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANKR5_MOUSE
NC score	0.373808 (rank : 121)	θ value	0.813845 (rank : 219)
Query Neighborhood Hits	353	Target Neighborhood Hits	298	Shared Neighborhood Hits	225
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKR5_HUMAN
NC score	0.373795 (rank : 122)	θ value	0.813845 (rank : 218)
Query Neighborhood Hits	353	Target Neighborhood Hits	297	Shared Neighborhood Hits	225
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANRA2_MOUSE
NC score	0.373766 (rank : 123)	θ value	5.27518 (rank : 307)
Query Neighborhood Hits	353	Target Neighborhood Hits	287	Shared Neighborhood Hits	222
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

BARD1_MOUSE
NC score	0.373328 (rank : 124)	θ value	0.000602161 (rank : 64)
Query Neighborhood Hits	353	Target Neighborhood Hits	411	Shared Neighborhood Hits	221
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ASB3_HUMAN
NC score	0.371989 (rank : 125)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	224
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

TRPA1_MOUSE
NC score	0.371972 (rank : 126)	θ value	0.0431538 (rank : 133)
Query Neighborhood Hits	353	Target Neighborhood Hits	343	Shared Neighborhood Hits	226
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

IKBE_HUMAN
NC score	0.368449 (rank : 127)	θ value	0.163984 (rank : 176)
Query Neighborhood Hits	353	Target Neighborhood Hits	288	Shared Neighborhood Hits	222
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

SNCAP_HUMAN
NC score	0.368101 (rank : 128)	θ value	0.00298849 (rank : 91)
Query Neighborhood Hits	353	Target Neighborhood Hits	313	Shared Neighborhood Hits	203
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

EHMT2_HUMAN
NC score	0.368047 (rank : 129)	θ value	0.0431538 (rank : 131)
Query Neighborhood Hits	353	Target Neighborhood Hits	498	Shared Neighborhood Hits	234
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANR45_MOUSE
NC score	0.367831 (rank : 130)	θ value	0.0148317 (rank : 112)
Query Neighborhood Hits	353	Target Neighborhood Hits	204	Shared Neighborhood Hits	163
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

PP16A_MOUSE
NC score	0.366957 (rank : 131)	θ value	1.81305 (rank : 255)
Query Neighborhood Hits	353	Target Neighborhood Hits	318	Shared Neighborhood Hits	225
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ANR49_MOUSE
NC score	0.366409 (rank : 132)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	353	Target Neighborhood Hits	285	Shared Neighborhood Hits	221
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANKS6_HUMAN
NC score	0.364358 (rank : 133)	θ value	0.125558 (rank : 162)
Query Neighborhood Hits	353	Target Neighborhood Hits	411	Shared Neighborhood Hits	231
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

TRPA1_HUMAN
NC score	0.362408 (rank : 134)	θ value	0.0736092 (rank : 151)
Query Neighborhood Hits	353	Target Neighborhood Hits	339	Shared Neighborhood Hits	226
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

PP16B_MOUSE
NC score	0.361708 (rank : 135)	θ value	6.88961 (rank : 336)
Query Neighborhood Hits	353	Target Neighborhood Hits	302	Shared Neighborhood Hits	225
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

PP16B_HUMAN
NC score	0.361575 (rank : 136)	θ value	1.81305 (rank : 256)
Query Neighborhood Hits	353	Target Neighborhood Hits	307	Shared Neighborhood Hits	228
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

CDN2D_HUMAN
NC score	0.359726 (rank : 137)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	353	Target Neighborhood Hits	268	Shared Neighborhood Hits	215
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ACBD6_MOUSE
NC score	0.359042 (rank : 138)	θ value	6.88961 (rank : 319)
Query Neighborhood Hits	353	Target Neighborhood Hits	305	Shared Neighborhood Hits	225
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

EHMT2_MOUSE
NC score	0.358397 (rank : 139)	θ value	0.0330416 (rank : 126)
Query Neighborhood Hits	353	Target Neighborhood Hits	750	Shared Neighborhood Hits	243
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANKS1_HUMAN
NC score	0.357167 (rank : 140)	θ value	0.47712 (rank : 199)
Query Neighborhood Hits	353	Target Neighborhood Hits	438	Shared Neighborhood Hits	229
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ASB15_HUMAN
NC score	0.357107 (rank : 141)	θ value	0.21417 (rank : 180)
Query Neighborhood Hits	353	Target Neighborhood Hits	305	Shared Neighborhood Hits	225
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ACBD6_HUMAN
NC score	0.356742 (rank : 142)	θ value	4.03905 (rank : 285)
Query Neighborhood Hits	353	Target Neighborhood Hits	304	Shared Neighborhood Hits	222
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANKS1_MOUSE
NC score	0.355311 (rank : 143)	θ value	0.813845 (rank : 220)
Query Neighborhood Hits	353	Target Neighborhood Hits	453	Shared Neighborhood Hits	233
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANKS3_MOUSE
NC score	0.355220 (rank : 144)	θ value	5.27518 (rank : 306)
Query Neighborhood Hits	353	Target Neighborhood Hits	355	Shared Neighborhood Hits	227
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

CTTB2_HUMAN
NC score	0.355092 (rank : 145)	θ value	5.44631e-05 (rank : 44)
Query Neighborhood Hits	353	Target Neighborhood Hits	1061	Shared Neighborhood Hits	259
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANKS6_MOUSE
NC score	0.354891 (rank : 146)	θ value	0.47712 (rank : 200)
Query Neighborhood Hits	353	Target Neighborhood Hits	435	Shared Neighborhood Hits	232
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

PP16A_HUMAN
NC score	0.353732 (rank : 147)	θ value	5.27518 (rank : 315)
Query Neighborhood Hits	353	Target Neighborhood Hits	340	Shared Neighborhood Hits	223
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ANR16_HUMAN
NC score	0.353696 (rank : 148)	θ value	1.38821 (rank : 235)
Query Neighborhood Hits	353	Target Neighborhood Hits	286	Shared Neighborhood Hits	224
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ASB14_MOUSE
NC score	0.353288 (rank : 149)	θ value	0.125558 (rank : 164)
Query Neighborhood Hits	353	Target Neighborhood Hits	293	Shared Neighborhood Hits	224
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CDN2C_HUMAN
NC score	0.352891 (rank : 150)	θ value	1.38821 (rank : 238)
Query Neighborhood Hits	353	Target Neighborhood Hits	262	Shared Neighborhood Hits	217
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CDN2C_MOUSE
NC score	0.351984 (rank : 151)	θ value	0.47712 (rank : 203)
Query Neighborhood Hits	353	Target Neighborhood Hits	270	Shared Neighborhood Hits	217
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

RFXK_HUMAN
NC score	0.351081 (rank : 152)	θ value	4.03905 (rank : 303)
Query Neighborhood Hits	353	Target Neighborhood Hits	282	Shared Neighborhood Hits	218
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ANKR7_HUMAN
NC score	0.350500 (rank : 153)	θ value	0.0431538 (rank : 129)
Query Neighborhood Hits	353	Target Neighborhood Hits	286	Shared Neighborhood Hits	222
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

HRBL_HUMAN
NC score	0.349680 (rank : 154)	θ value	0.0563607 (rank : 143)
Query Neighborhood Hits	353	Target Neighborhood Hits	179	Shared Neighborhood Hits	42
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

ASZ1_MOUSE
NC score	0.349532 (rank : 155)	θ value	6.88961 (rank : 325)
Query Neighborhood Hits	353	Target Neighborhood Hits	319	Shared Neighborhood Hits	226
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

CDN2D_MOUSE
NC score	0.349035 (rank : 156)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	213
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB15_MOUSE
NC score	0.348696 (rank : 157)	θ value	0.0563607 (rank : 139)
Query Neighborhood Hits	353	Target Neighborhood Hits	292	Shared Neighborhood Hits	219
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

AN36B_HUMAN
NC score	0.347973 (rank : 158)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	353	Target Neighborhood Hits	294	Shared Neighborhood Hits	223
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

IKBA_HUMAN
NC score	0.347272 (rank : 159)	θ value	0.813845 (rank : 221)
Query Neighborhood Hits	353	Target Neighborhood Hits	280	Shared Neighborhood Hits	223
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ASB4_MOUSE
NC score	0.347212 (rank : 160)	θ value	0.47712 (rank : 202)
Query Neighborhood Hits	353	Target Neighborhood Hits	265	Shared Neighborhood Hits	219
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB11_MOUSE
NC score	0.346934 (rank : 161)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	353	Target Neighborhood Hits	271	Shared Neighborhood Hits	216
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANR19_HUMAN
NC score	0.346394 (rank : 162)	θ value	0.0431538 (rank : 130)
Query Neighborhood Hits	353	Target Neighborhood Hits	276	Shared Neighborhood Hits	220
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

AN36A_HUMAN
NC score	0.344688 (rank : 163)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	353	Target Neighborhood Hits	271	Shared Neighborhood Hits	220
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR45_HUMAN
NC score	0.344595 (rank : 164)	θ value	0.00134147 (rank : 71)
Query Neighborhood Hits	353	Target Neighborhood Hits	201	Shared Neighborhood Hits	159
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ZDH17_HUMAN
NC score	0.343993 (rank : 165)	θ value	0.0252991 (rank : 125)
Query Neighborhood Hits	353	Target Neighborhood Hits	334	Shared Neighborhood Hits	225
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANKS3_HUMAN
NC score	0.343735 (rank : 166)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	353	Target Neighborhood Hits	355	Shared Neighborhood Hits	224
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB4_HUMAN
NC score	0.343717 (rank : 167)	θ value	3.0926 (rank : 275)
Query Neighborhood Hits	353	Target Neighborhood Hits	264	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

POTE8_HUMAN
NC score	0.343568 (rank : 168)	θ value	1.06291 (rank : 232)
Query Neighborhood Hits	353	Target Neighborhood Hits	337	Shared Neighborhood Hits	225
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

SHAN1_HUMAN
NC score	0.343336 (rank : 169)	θ value	0.00228821 (rank : 86)
Query Neighborhood Hits	353	Target Neighborhood Hits	1041	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ASB12_MOUSE
NC score	0.341624 (rank : 170)	θ value	0.62314 (rank : 209)
Query Neighborhood Hits	353	Target Neighborhood Hits	261	Shared Neighborhood Hits	217
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

RFXK_MOUSE
NC score	0.341528 (rank : 171)	θ value	5.27518 (rank : 316)
Query Neighborhood Hits	353	Target Neighborhood Hits	273	Shared Neighborhood Hits	221
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ASB9_HUMAN
NC score	0.341414 (rank : 172)	θ value	1.81305 (rank : 246)
Query Neighborhood Hits	353	Target Neighborhood Hits	267	Shared Neighborhood Hits	210
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

IKBA_MOUSE
NC score	0.341280 (rank : 173)	θ value	1.06291 (rank : 228)
Query Neighborhood Hits	353	Target Neighborhood Hits	283	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ANR15_HUMAN
NC score	0.341175 (rank : 174)	θ value	1.06291 (rank : 222)
Query Neighborhood Hits	353	Target Neighborhood Hits	478	Shared Neighborhood Hits	234
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ZDH17_MOUSE
NC score	0.340767 (rank : 175)	θ value	0.0563607 (rank : 148)
Query Neighborhood Hits	353	Target Neighborhood Hits	328	Shared Neighborhood Hits	224
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ASB11_HUMAN
NC score	0.340703 (rank : 176)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	353	Target Neighborhood Hits	271	Shared Neighborhood Hits	216
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

HRBL_MOUSE
NC score	0.340098 (rank : 177)	θ value	0.0330416 (rank : 127)
Query Neighborhood Hits	353	Target Neighborhood Hits	269	Shared Neighborhood Hits	50
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

ASZ1_HUMAN
NC score	0.339584 (rank : 178)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	353	Target Neighborhood Hits	341	Shared Neighborhood Hits	228
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ANFY1_HUMAN
NC score	0.338827 (rank : 179)	θ value	0.0563607 (rank : 134)
Query Neighborhood Hits	353	Target Neighborhood Hits	480	Shared Neighborhood Hits	229
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASB5_HUMAN
NC score	0.337809 (rank : 180)	θ value	3.0926 (rank : 276)
Query Neighborhood Hits	353	Target Neighborhood Hits	283	Shared Neighborhood Hits	220
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANFY1_MOUSE
NC score	0.337499 (rank : 181)	θ value	0.0563607 (rank : 135)
Query Neighborhood Hits	353	Target Neighborhood Hits	480	Shared Neighborhood Hits	229
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASB1_HUMAN
NC score	0.337126 (rank : 182)	θ value	4.03905 (rank : 288)
Query Neighborhood Hits	353	Target Neighborhood Hits	291	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB12_HUMAN
NC score	0.337083 (rank : 183)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	353	Target Neighborhood Hits	263	Shared Neighborhood Hits	216
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB1_MOUSE
NC score	0.336312 (rank : 184)	θ value	1.38821 (rank : 237)
Query Neighborhood Hits	353	Target Neighborhood Hits	292	Shared Neighborhood Hits	218
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

RN5A_HUMAN
NC score	0.334295 (rank : 185)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	353	Target Neighborhood Hits	608	Shared Neighborhood Hits	227
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

HECD1_HUMAN
NC score	0.332781 (rank : 186)	θ value	0.000270298 (rank : 53)
Query Neighborhood Hits	353	Target Neighborhood Hits	371	Shared Neighborhood Hits	224
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ASB5_MOUSE
NC score	0.331065 (rank : 187)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	353	Target Neighborhood Hits	266	Shared Neighborhood Hits	212
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB9_MOUSE
NC score	0.328873 (rank : 188)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	353	Target Neighborhood Hits	257	Shared Neighborhood Hits	203
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ZDH13_MOUSE
NC score	0.325713 (rank : 189)	θ value	1.81305 (rank : 259)
Query Neighborhood Hits	353	Target Neighborhood Hits	329	Shared Neighborhood Hits	224
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ANR21_HUMAN
NC score	0.323161 (rank : 190)	θ value	0.279714 (rank : 186)
Query Neighborhood Hits	353	Target Neighborhood Hits	864	Shared Neighborhood Hits	250
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

POT15_HUMAN
NC score	0.322301 (rank : 191)	θ value	0.0961366 (rank : 159)
Query Neighborhood Hits	353	Target Neighborhood Hits	893	Shared Neighborhood Hits	251
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ZDH13_HUMAN
NC score	0.321250 (rank : 192)	θ value	1.38821 (rank : 241)
Query Neighborhood Hits	353	Target Neighborhood Hits	322	Shared Neighborhood Hits	223
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ANR47_MOUSE
NC score	0.319796 (rank : 193)	θ value	1.38821 (rank : 236)
Query Neighborhood Hits	353	Target Neighborhood Hits	350	Shared Neighborhood Hits	220
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

POT14_HUMAN
NC score	0.319482 (rank : 194)	θ value	4.03905 (rank : 301)
Query Neighborhood Hits	353	Target Neighborhood Hits	403	Shared Neighborhood Hits	223
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

NFKB1_HUMAN
NC score	0.319454 (rank : 195)	θ value	0.125558 (rank : 169)
Query Neighborhood Hits	353	Target Neighborhood Hits	306	Shared Neighborhood Hits	224
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

NFKB1_MOUSE
NC score	0.316536 (rank : 196)	θ value	1.06291 (rank : 229)
Query Neighborhood Hits	353	Target Neighborhood Hits	300	Shared Neighborhood Hits	220
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ANR12_HUMAN
NC score	0.315082 (rank : 197)	θ value	1.81305 (rank : 244)
Query Neighborhood Hits	353	Target Neighborhood Hits	1081	Shared Neighborhood Hits	255
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

RAI14_HUMAN
NC score	0.314074 (rank : 198)	θ value	0.0148317 (rank : 115)
Query Neighborhood Hits	353	Target Neighborhood Hits	1367	Shared Neighborhood Hits	265
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

NFKB2_HUMAN
NC score	0.313660 (rank : 199)	θ value	1.81305 (rank : 253)
Query Neighborhood Hits	353	Target Neighborhood Hits	325	Shared Neighborhood Hits	223
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANKY2_HUMAN
NC score	0.313291 (rank : 200)	θ value	1.81305 (rank : 243)
Query Neighborhood Hits	353	Target Neighborhood Hits	306	Shared Neighborhood Hits	210
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR33_HUMAN
NC score	0.312171 (rank : 201)	θ value	3.0926 (rank : 272)
Query Neighborhood Hits	353	Target Neighborhood Hits	215	Shared Neighborhood Hits	190
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR11_HUMAN
NC score	0.311890 (rank : 202)	θ value	6.88961 (rank : 322)
Query Neighborhood Hits	353	Target Neighborhood Hits	1289	Shared Neighborhood Hits	263
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

NFKB2_MOUSE
NC score	0.310951 (rank : 203)	θ value	0.163984 (rank : 178)
Query Neighborhood Hits	353	Target Neighborhood Hits	326	Shared Neighborhood Hits	222
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

RN5A_MOUSE
NC score	0.309331 (rank : 204)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	353	Target Neighborhood Hits	899	Shared Neighborhood Hits	225
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

OSTF1_MOUSE
NC score	0.307337 (rank : 205)	θ value	0.365318 (rank : 196)
Query Neighborhood Hits	353	Target Neighborhood Hits	467	Shared Neighborhood Hits	212
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

A20A2_HUMAN
NC score	0.306585 (rank : 206)	θ value	0.365318 (rank : 191)
Query Neighborhood Hits	353	Target Neighborhood Hits	716	Shared Neighborhood Hits	246
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A3_HUMAN
NC score	0.306534 (rank : 207)	θ value	0.365318 (rank : 192)
Query Neighborhood Hits	353	Target Neighborhood Hits	692	Shared Neighborhood Hits	246
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

ANR32_HUMAN
NC score	0.305261 (rank : 208)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	353	Target Neighborhood Hits	270	Shared Neighborhood Hits	212
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

A20A1_HUMAN
NC score	0.305228 (rank : 209)	θ value	0.365318 (rank : 190)
Query Neighborhood Hits	353	Target Neighborhood Hits	698	Shared Neighborhood Hits	245
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

ANR47_HUMAN
NC score	0.305148 (rank : 210)	θ value	2.36792 (rank : 263)
Query Neighborhood Hits	353	Target Neighborhood Hits	369	Shared Neighborhood Hits	218
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

A20A4_HUMAN
NC score	0.304648 (rank : 211)	θ value	0.365318 (rank : 193)
Query Neighborhood Hits	353	Target Neighborhood Hits	710	Shared Neighborhood Hits	246
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR32_MOUSE
NC score	0.304277 (rank : 212)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	353	Target Neighborhood Hits	285	Shared Neighborhood Hits	212
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR33_MOUSE
NC score	0.302743 (rank : 213)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	353	Target Neighborhood Hits	225	Shared Neighborhood Hits	195
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

POT22_HUMAN
NC score	0.301518 (rank : 214)	θ value	6.88961 (rank : 335)
Query Neighborhood Hits	353	Target Neighborhood Hits	266	Shared Neighborhood Hits	216
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

RAI14_MOUSE
NC score	0.300539 (rank : 215)	θ value	0.00665767 (rank : 102)
Query Neighborhood Hits	353	Target Neighborhood Hits	1505	Shared Neighborhood Hits	262
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

OSBL1_HUMAN
NC score	0.299705 (rank : 216)	θ value	0.0961366 (rank : 157)
Query Neighborhood Hits	353	Target Neighborhood Hits	368	Shared Neighborhood Hits	231
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR25_HUMAN
NC score	0.299119 (rank : 217)	θ value	0.0563607 (rank : 136)
Query Neighborhood Hits	353	Target Neighborhood Hits	350	Shared Neighborhood Hits	219
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANKY2_MOUSE
NC score	0.298980 (rank : 218)	θ value	4.03905 (rank : 287)
Query Neighborhood Hits	353	Target Neighborhood Hits	316	Shared Neighborhood Hits	210
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ASB6_HUMAN
NC score	0.296025 (rank : 219)	θ value	0.62314 (rank : 210)
Query Neighborhood Hits	353	Target Neighborhood Hits	256	Shared Neighborhood Hits	203
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

OSBL1_MOUSE
NC score	0.294146 (rank : 220)	θ value	0.279714 (rank : 189)
Query Neighborhood Hits	353	Target Neighborhood Hits	336	Shared Neighborhood Hits	228
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

IASPP_HUMAN
NC score	0.291255 (rank : 221)	θ value	0.0193708 (rank : 117)
Query Neighborhood Hits	353	Target Neighborhood Hits	688	Shared Neighborhood Hits	228
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NUD12_MOUSE
NC score	0.291013 (rank : 222)	θ value	0.00228821 (rank : 84)
Query Neighborhood Hits	353	Target Neighborhood Hits	243	Shared Neighborhood Hits	191
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ASB6_MOUSE
NC score	0.290866 (rank : 223)	θ value	1.06291 (rank : 223)
Query Neighborhood Hits	353	Target Neighborhood Hits	264	Shared Neighborhood Hits	206
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CLPB_MOUSE
NC score	0.290550 (rank : 224)	θ value	0.62314 (rank : 211)
Query Neighborhood Hits	353	Target Neighborhood Hits	289	Shared Neighborhood Hits	203
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

BCOR_MOUSE
NC score	0.288904 (rank : 225)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	353	Target Neighborhood Hits	521	Shared Neighborhood Hits	230
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

MPP8_HUMAN
NC score	0.287223 (rank : 226)	θ value	0.125558 (rank : 167)
Query Neighborhood Hits	353	Target Neighborhood Hits	948	Shared Neighborhood Hits	233
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ANR25_MOUSE
NC score	0.284032 (rank : 227)	θ value	0.0961366 (rank : 152)
Query Neighborhood Hits	353	Target Neighborhood Hits	398	Shared Neighborhood Hits	215
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

OSTF1_HUMAN
NC score	0.283915 (rank : 228)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	353	Target Neighborhood Hits	466	Shared Neighborhood Hits	212
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ANR18_HUMAN
NC score	0.282468 (rank : 229)	θ value	0.125558 (rank : 163)
Query Neighborhood Hits	353	Target Neighborhood Hits	1106	Shared Neighborhood Hits	253
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

BCOR_HUMAN
NC score	0.282416 (rank : 230)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	353	Target Neighborhood Hits	609	Shared Neighborhood Hits	234
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CD2A1_MOUSE
NC score	0.279079 (rank : 231)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	353	Target Neighborhood Hits	206	Shared Neighborhood Hits	172
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

NUD12_HUMAN
NC score	0.278578 (rank : 232)	θ value	0.0148317 (rank : 114)
Query Neighborhood Hits	353	Target Neighborhood Hits	222	Shared Neighborhood Hits	173
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

IASPP_MOUSE
NC score	0.276356 (rank : 233)	θ value	0.00175202 (rank : 78)
Query Neighborhood Hits	353	Target Neighborhood Hits	1024	Shared Neighborhood Hits	235
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ASPP2_HUMAN
NC score	0.274529 (rank : 234)	θ value	0.125558 (rank : 165)
Query Neighborhood Hits	353	Target Neighborhood Hits	1156	Shared Neighborhood Hits	261
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ANR43_HUMAN
NC score	0.274003 (rank : 235)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	353	Target Neighborhood Hits	209	Shared Neighborhood Hits	179
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR38_HUMAN
NC score	0.272397 (rank : 236)	θ value	2.36792 (rank : 262)
Query Neighborhood Hits	353	Target Neighborhood Hits	443	Shared Neighborhood Hits	218
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CLPB_HUMAN
NC score	0.268456 (rank : 237)	θ value	0.365318 (rank : 194)
Query Neighborhood Hits	353	Target Neighborhood Hits	265	Shared Neighborhood Hits	196
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR43_MOUSE
NC score	0.267864 (rank : 238)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	353	Target Neighborhood Hits	214	Shared Neighborhood Hits	181
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ASPP1_HUMAN
NC score	0.262833 (rank : 239)	θ value	1.06291 (rank : 224)
Query Neighborhood Hits	353	Target Neighborhood Hits	956	Shared Neighborhood Hits	250
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
NC score	0.260607 (rank : 240)	θ value	1.06291 (rank : 225)
Query Neighborhood Hits	353	Target Neighborhood Hits	1244	Shared Neighborhood Hits	259
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ANR38_MOUSE
NC score	0.258799 (rank : 241)	θ value	8.99809 (rank : 341)
Query Neighborhood Hits	353	Target Neighborhood Hits	512	Shared Neighborhood Hits	218
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

KRIT1_MOUSE
NC score	0.255723 (rank : 242)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	353	Target Neighborhood Hits	258	Shared Neighborhood Hits	192
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

CD2A1_HUMAN
NC score	0.255388 (rank : 243)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	353	Target Neighborhood Hits	196	Shared Neighborhood Hits	163
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

KRIT1_HUMAN
NC score	0.252300 (rank : 244)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	353	Target Neighborhood Hits	258	Shared Neighborhood Hits	186
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

AN13C_HUMAN
NC score	0.249187 (rank : 245)	θ value	8.99809 (rank : 340)
Query Neighborhood Hits	353	Target Neighborhood Hits	241	Shared Neighborhood Hits	203
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ILK2_HUMAN
NC score	0.248973 (rank : 246)	θ value	0.0252991 (rank : 123)
Query Neighborhood Hits	353	Target Neighborhood Hits	848	Shared Neighborhood Hits	223
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

AN13B_MOUSE
NC score	0.248761 (rank : 247)	θ value	3.0926 (rank : 271)
Query Neighborhood Hits	353	Target Neighborhood Hits	276	Shared Neighborhood Hits	213
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_HUMAN
NC score	0.248668 (rank : 248)	θ value	3.0926 (rank : 270)
Query Neighborhood Hits	353	Target Neighborhood Hits	265	Shared Neighborhood Hits	213
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN30A_HUMAN
NC score	0.248196 (rank : 249)	θ value	1.81305 (rank : 242)
Query Neighborhood Hits	353	Target Neighborhood Hits	1119	Shared Neighborhood Hits	251
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

CDN2B_MOUSE
NC score	0.245303 (rank : 250)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	353	Target Neighborhood Hits	201	Shared Neighborhood Hits	168
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

AN13C_MOUSE
NC score	0.243970 (rank : 251)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	353	Target Neighborhood Hits	242	Shared Neighborhood Hits	199
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

UACA_HUMAN
NC score	0.241572 (rank : 252)	θ value	4.03905 (rank : 305)
Query Neighborhood Hits	353	Target Neighborhood Hits	1622	Shared Neighborhood Hits	262
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

CDN2B_HUMAN
NC score	0.240887 (rank : 253)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	353	Target Neighborhood Hits	196	Shared Neighborhood Hits	164
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

ILK1_HUMAN
NC score	0.240213 (rank : 254)	θ value	0.0252991 (rank : 122)
Query Neighborhood Hits	353	Target Neighborhood Hits	857	Shared Neighborhood Hits	223
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

RIPK4_HUMAN
NC score	0.238738 (rank : 255)	θ value	0.00665767 (rank : 103)
Query Neighborhood Hits	353	Target Neighborhood Hits	1094	Shared Neighborhood Hits	230
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANKK1_HUMAN
NC score	0.237703 (rank : 256)	θ value	0.163984 (rank : 173)
Query Neighborhood Hits	353	Target Neighborhood Hits	1075	Shared Neighborhood Hits	229
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ILK_MOUSE
NC score	0.236768 (rank : 257)	θ value	0.0563607 (rank : 145)
Query Neighborhood Hits	353	Target Neighborhood Hits	858	Shared Neighborhood Hits	224
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

UACA_MOUSE
NC score	0.236041 (rank : 258)	θ value	0.0961366 (rank : 160)
Query Neighborhood Hits	353	Target Neighborhood Hits	1620	Shared Neighborhood Hits	257
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ANKK1_MOUSE
NC score	0.233911 (rank : 259)	θ value	0.47712 (rank : 198)
Query Neighborhood Hits	353	Target Neighborhood Hits	1072	Shared Neighborhood Hits	229
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANR40_HUMAN
NC score	0.227585 (rank : 260)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	353	Target Neighborhood Hits	224	Shared Neighborhood Hits	170
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
NC score	0.224684 (rank : 261)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	353	Target Neighborhood Hits	228	Shared Neighborhood Hits	173
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR26_MOUSE
NC score	0.220466 (rank : 262)	θ value	0.47712 (rank : 201)
Query Neighborhood Hits	353	Target Neighborhood Hits	1554	Shared Neighborhood Hits	265
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ABTB2_HUMAN
NC score	0.218142 (rank : 263)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	353	Target Neighborhood Hits	391	Shared Neighborhood Hits	196
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ABTB2_MOUSE
NC score	0.211319 (rank : 264)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	353	Target Neighborhood Hits	414	Shared Neighborhood Hits	196
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

NOTC4_MOUSE
NC score	0.204123 (rank : 265)	θ value	1.81305 (rank : 254)
Query Neighborhood Hits	353	Target Neighborhood Hits	872	Shared Neighborhood Hits	226
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

TNI3K_HUMAN
NC score	0.201612 (rank : 266)	θ value	0.0193708 (rank : 118)
Query Neighborhood Hits	353	Target Neighborhood Hits	1084	Shared Neighborhood Hits	229
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANR26_HUMAN
NC score	0.200531 (rank : 267)	θ value	1.81305 (rank : 245)
Query Neighborhood Hits	353	Target Neighborhood Hits	1614	Shared Neighborhood Hits	262
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANKY1_HUMAN
NC score	0.200380 (rank : 268)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	353	Target Neighborhood Hits	248	Shared Neighborhood Hits	173
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

DP13A_HUMAN
NC score	0.199359 (rank : 269)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	353	Target Neighborhood Hits	107	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

TRPV6_MOUSE
NC score	0.199212 (rank : 270)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	353	Target Neighborhood Hits	284	Shared Neighborhood Hits	203
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

NOTC4_HUMAN
NC score	0.199176 (rank : 271)	θ value	3.0926 (rank : 280)
Query Neighborhood Hits	353	Target Neighborhood Hits	905	Shared Neighborhood Hits	232
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

DP13B_MOUSE
NC score	0.198992 (rank : 272)	θ value	0.163984 (rank : 175)
Query Neighborhood Hits	353	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

GLSL_HUMAN
NC score	0.198646 (rank : 273)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	353	Target Neighborhood Hits	211	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

TNI3K_MOUSE
NC score	0.197665 (rank : 274)	θ value	0.00869519 (rank : 106)
Query Neighborhood Hits	353	Target Neighborhood Hits	1079	Shared Neighborhood Hits	229
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

DP13A_MOUSE
NC score	0.195684 (rank : 275)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	353	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DGKI_HUMAN
NC score	0.194798 (rank : 276)	θ value	0.0148317 (rank : 113)
Query Neighborhood Hits	353	Target Neighborhood Hits	609	Shared Neighborhood Hits	188
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

OPHN1_MOUSE
NC score	0.191845 (rank : 277)	θ value	0.000461057 (rank : 63)
Query Neighborhood Hits	353	Target Neighborhood Hits	174	Shared Neighborhood Hits	25
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

AN13A_HUMAN
NC score	0.191765 (rank : 278)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	353	Target Neighborhood Hits	243	Shared Neighborhood Hits	187
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ASB14_HUMAN
NC score	0.191394 (rank : 279)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	353	Target Neighborhood Hits	187	Shared Neighborhood Hits	155
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

GLSL_MOUSE
NC score	0.191228 (rank : 280)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	353	Target Neighborhood Hits	212	Shared Neighborhood Hits	162
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

DP13B_HUMAN
NC score	0.185463 (rank : 281)	θ value	0.00298849 (rank : 90)
Query Neighborhood Hits	353	Target Neighborhood Hits	58	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

TRPV5_MOUSE
NC score	0.184821 (rank : 282)	θ value	6.88961 (rank : 338)
Query Neighborhood Hits	353	Target Neighborhood Hits	278	Shared Neighborhood Hits	202
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

AN13A_MOUSE
NC score	0.181057 (rank : 283)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	353	Target Neighborhood Hits	226	Shared Neighborhood Hits	185
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

NOTC3_MOUSE
NC score	0.180959 (rank : 284)	θ value	0.21417 (rank : 183)
Query Neighborhood Hits	353	Target Neighborhood Hits	975	Shared Neighborhood Hits	235
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CT012_MOUSE
NC score	0.180872 (rank : 285)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	353	Target Neighborhood Hits	229	Shared Neighborhood Hits	151
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

NOTC3_HUMAN
NC score	0.179354 (rank : 286)	θ value	0.21417 (rank : 182)
Query Neighborhood Hits	353	Target Neighborhood Hits	1062	Shared Neighborhood Hits	233
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

DAPK1_MOUSE
NC score	0.178824 (rank : 287)	θ value	0.00035302 (rank : 58)
Query Neighborhood Hits	353	Target Neighborhood Hits	1138	Shared Neighborhood Hits	229
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

GLSK_HUMAN
NC score	0.175843 (rank : 288)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	353	Target Neighborhood Hits	204	Shared Neighborhood Hits	159
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

DGKZ_HUMAN
NC score	0.172260 (rank : 289)	θ value	3.0926 (rank : 277)
Query Neighborhood Hits	353	Target Neighborhood Hits	551	Shared Neighborhood Hits	189
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

NOTC2_HUMAN
NC score	0.171076 (rank : 290)	θ value	4.03905 (rank : 299)
Query Neighborhood Hits	353	Target Neighborhood Hits	1113	Shared Neighborhood Hits	229
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DAPK1_HUMAN
NC score	0.170782 (rank : 291)	θ value	0.00665767 (rank : 101)
Query Neighborhood Hits	353	Target Neighborhood Hits	1130	Shared Neighborhood Hits	228
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

NOTC2_MOUSE
NC score	0.170476 (rank : 292)	θ value	4.03905 (rank : 300)
Query Neighborhood Hits	353	Target Neighborhood Hits	1069	Shared Neighborhood Hits	230
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_HUMAN
NC score	0.169181 (rank : 293)	θ value	0.279714 (rank : 188)
Query Neighborhood Hits	353	Target Neighborhood Hits	906	Shared Neighborhood Hits	226
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANKR9_MOUSE
NC score	0.167993 (rank : 294)	θ value	6.88961 (rank : 321)
Query Neighborhood Hits	353	Target Neighborhood Hits	120	Shared Neighborhood Hits	109
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

TRPV5_HUMAN
NC score	0.163764 (rank : 295)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	353	Target Neighborhood Hits	261	Shared Neighborhood Hits	179
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TEX14_MOUSE
NC score	0.163287 (rank : 296)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	353	Target Neighborhood Hits	1333	Shared Neighborhood Hits	243
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CT012_HUMAN
NC score	0.162794 (rank : 297)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	353	Target Neighborhood Hits	205	Shared Neighborhood Hits	145
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

OPHN1_HUMAN
NC score	0.162271 (rank : 298)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	353	Target Neighborhood Hits	161	Shared Neighborhood Hits	20
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

TRPV6_HUMAN
NC score	0.162158 (rank : 299)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	353	Target Neighborhood Hits	262	Shared Neighborhood Hits	181
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TEX14_HUMAN
NC score	0.160747 (rank : 300)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	353	Target Neighborhood Hits	1103	Shared Neighborhood Hits	224
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

RHG26_HUMAN
NC score	0.153959 (rank : 301)	θ value	0.00228821 (rank : 85)
Query Neighborhood Hits	353	Target Neighborhood Hits	281	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

DGKZ_MOUSE
NC score	0.148151 (rank : 302)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	353	Target Neighborhood Hits	542	Shared Neighborhood Hits	176
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

NOTC1_MOUSE
NC score	0.139232 (rank : 303)	θ value	1.06291 (rank : 230)
Query Neighborhood Hits	353	Target Neighborhood Hits	916	Shared Neighborhood Hits	216
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PKHA6_MOUSE
NC score	0.137393 (rank : 304)	θ value	0.0113563 (rank : 111)
Query Neighborhood Hits	353	Target Neighborhood Hits	591	Shared Neighborhood Hits	67
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

IKBL_HUMAN
NC score	0.136810 (rank : 305)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	353	Target Neighborhood Hits	168	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

PKHA1_HUMAN
NC score	0.133754 (rank : 306)	θ value	0.0961366 (rank : 158)
Query Neighborhood Hits	353	Target Neighborhood Hits	127	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

ANKR9_HUMAN
NC score	0.132909 (rank : 307)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	353	Target Neighborhood Hits	99	Shared Neighborhood Hits	90
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

IKBL_MOUSE
NC score	0.132887 (rank : 308)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	353	Target Neighborhood Hits	196	Shared Neighborhood Hits	123
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

ANKZ1_MOUSE
NC score	0.130089 (rank : 309)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	353	Target Neighborhood Hits	208	Shared Neighborhood Hits	130
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

PKHA6_HUMAN
NC score	0.128629 (rank : 310)	θ value	0.125558 (rank : 171)
Query Neighborhood Hits	353	Target Neighborhood Hits	556	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA1_MOUSE
NC score	0.128048 (rank : 311)	θ value	1.06291 (rank : 231)
Query Neighborhood Hits	353	Target Neighborhood Hits	120	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

ANKZ1_HUMAN
NC score	0.121456 (rank : 312)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	353	Target Neighborhood Hits	236	Shared Neighborhood Hits	139
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

CLR59_HUMAN
NC score	0.117469 (rank : 313)	θ value	5.27518 (rank : 308)
Query Neighborhood Hits	353	Target Neighborhood Hits	163	Shared Neighborhood Hits	129
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

BAT4_HUMAN
NC score	0.113852 (rank : 314)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	353	Target Neighborhood Hits	157	Shared Neighborhood Hits	96
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BAT4_MOUSE
NC score	0.112302 (rank : 315)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	353	Target Neighborhood Hits	171	Shared Neighborhood Hits	107
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

OSBP1_HUMAN
NC score	0.103786 (rank : 316)	θ value	5.27518 (rank : 314)
Query Neighborhood Hits	353	Target Neighborhood Hits	180	Shared Neighborhood Hits	45
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

ABTB1_MOUSE
NC score	0.103158 (rank : 317)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	353	Target Neighborhood Hits	349	Shared Neighborhood Hits	143
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

PKHA2_MOUSE
NC score	0.099034 (rank : 318)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	353	Target Neighborhood Hits	116	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA2_HUMAN
NC score	0.094546 (rank : 319)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	353	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

TRPV1_MOUSE
NC score	0.090849 (rank : 320)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	353	Target Neighborhood Hits	189	Shared Neighborhood Hits	128
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

OSBL3_HUMAN
NC score	0.090027 (rank : 321)	θ value	0.0736092 (rank : 150)
Query Neighborhood Hits	353	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

ABTB1_HUMAN
NC score	0.089035 (rank : 322)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	353	Target Neighborhood Hits	325	Shared Neighborhood Hits	131
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

TRPV1_HUMAN
NC score	0.088140 (rank : 323)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	353	Target Neighborhood Hits	184	Shared Neighborhood Hits	126
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

OSBL3_MOUSE
NC score	0.088133 (rank : 324)	θ value	0.0563607 (rank : 146)
Query Neighborhood Hits	353	Target Neighborhood Hits	86	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PKHA5_HUMAN
NC score	0.085135 (rank : 325)	θ value	3.0926 (rank : 283)
Query Neighborhood Hits	353	Target Neighborhood Hits	455	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RSNL2_HUMAN
NC score	0.084111 (rank : 326)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	353	Target Neighborhood Hits	136	Shared Neighborhood Hits	103
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

DAPP1_MOUSE
NC score	0.079003 (rank : 327)	θ value	1.06291 (rank : 226)
Query Neighborhood Hits	353	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CMTA1_HUMAN
NC score	0.077610 (rank : 328)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	353	Target Neighborhood Hits	217	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

RSNL2_MOUSE
NC score	0.072879 (rank : 329)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	353	Target Neighborhood Hits	129	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

OSBL9_HUMAN
NC score	0.072813 (rank : 330)	θ value	0.62314 (rank : 215)
Query Neighborhood Hits	353	Target Neighborhood Hits	138	Shared Neighborhood Hits	38
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

TRPV3_HUMAN
NC score	0.072634 (rank : 331)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	353	Target Neighborhood Hits	198	Shared Neighborhood Hits	119
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TCGAP_HUMAN
NC score	0.072067 (rank : 332)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	353	Target Neighborhood Hits	872	Shared Neighborhood Hits	44
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TRPV3_MOUSE
NC score	0.071902 (rank : 333)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	353	Target Neighborhood Hits	188	Shared Neighborhood Hits	110
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

PKHA4_MOUSE
NC score	0.071724 (rank : 334)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	353	Target Neighborhood Hits	202	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_HUMAN
NC score	0.071386 (rank : 335)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	353	Target Neighborhood Hits	283	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

DAPP1_HUMAN
NC score	0.070980 (rank : 336)	θ value	1.81305 (rank : 248)
Query Neighborhood Hits	353	Target Neighborhood Hits	227	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

RHG09_HUMAN
NC score	0.068673 (rank : 337)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	353	Target Neighborhood Hits	186	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

TRPV2_HUMAN
NC score	0.067111 (rank : 338)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	353	Target Neighborhood Hits	130	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

RBP1_MOUSE
NC score	0.063647 (rank : 339)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	353	Target Neighborhood Hits	493	Shared Neighborhood Hits	48
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

OSBL6_HUMAN
NC score	0.062685 (rank : 340)	θ value	2.36792 (rank : 269)
Query Neighborhood Hits	353	Target Neighborhood Hits	101	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

CMTA2_HUMAN
NC score	0.062027 (rank : 341)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	353	Target Neighborhood Hits	199	Shared Neighborhood Hits	83
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

MYO10_HUMAN
NC score	0.061714 (rank : 342)	θ value	0.47712 (rank : 206)
Query Neighborhood Hits	353	Target Neighborhood Hits	920	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

RBP1_HUMAN
NC score	0.061669 (rank : 343)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	353	Target Neighborhood Hits	521	Shared Neighborhood Hits	47
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

OSBL6_MOUSE
NC score	0.061554 (rank : 344)	θ value	3.0926 (rank : 282)
Query Neighborhood Hits	353	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBP2_HUMAN
NC score	0.060987 (rank : 345)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	353	Target Neighborhood Hits	154	Shared Neighborhood Hits	29
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

TCGAP_MOUSE
NC score	0.060931 (rank : 346)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	353	Target Neighborhood Hits	409	Shared Neighborhood Hits	30
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG25_MOUSE
NC score	0.060667 (rank : 347)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	353	Target Neighborhood Hits	492	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

DGKH_HUMAN
NC score	0.059913 (rank : 348)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	353	Target Neighborhood Hits	255	Shared Neighborhood Hits	44
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

SH3K1_MOUSE
NC score	0.059890 (rank : 349)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	353	Target Neighborhood Hits	332	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

OSBP2_MOUSE
NC score	0.059766 (rank : 350)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	353	Target Neighborhood Hits	150	Shared Neighborhood Hits	33
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

SH3K1_HUMAN
NC score	0.059729 (rank : 351)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	353	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

RHG25_HUMAN
NC score	0.058392 (rank : 352)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	353	Target Neighborhood Hits	550	Shared Neighborhood Hits	65
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CMTA2_MOUSE
NC score	0.057481 (rank : 353)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	353	Target Neighborhood Hits	216	Shared Neighborhood Hits	71
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

RGAP1_HUMAN
NC score	0.056961 (rank : 354)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	353	Target Neighborhood Hits	189	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

SH3G1_MOUSE
NC score	0.056346 (rank : 355)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	353	Target Neighborhood Hits	291	Shared Neighborhood Hits	20
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3G1_HUMAN
NC score	0.055938 (rank : 356)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	353	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

RGAP1_MOUSE
NC score	0.055817 (rank : 357)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	353	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

ANKF1_HUMAN
NC score	0.054749 (rank : 358)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	353	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

GMIP_MOUSE
NC score	0.054716 (rank : 359)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	353	Target Neighborhood Hits	202	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

STAM2_MOUSE
NC score	0.054218 (rank : 360)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	353	Target Neighborhood Hits	285	Shared Neighborhood Hits	18
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

RHG05_MOUSE
NC score	0.053976 (rank : 361)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	353	Target Neighborhood Hits	165	Shared Neighborhood Hits	17
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

MYO9B_HUMAN
NC score	0.053960 (rank : 362)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	353	Target Neighborhood Hits	641	Shared Neighborhood Hits	58
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RHG05_HUMAN
NC score	0.053642 (rank : 363)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	353	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

GMIP_HUMAN
NC score	0.053074 (rank : 364)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	353	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

NCF2_HUMAN
NC score	0.052746 (rank : 365)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	353	Target Neighborhood Hits	229	Shared Neighborhood Hits	12
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

WASIP_HUMAN
NC score	0.052541 (rank : 366)	θ value	0.125558 (rank : 172)
Query Neighborhood Hits	353	Target Neighborhood Hits	458	Shared Neighborhood Hits	32
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BCR_HUMAN
NC score	0.052493 (rank : 367)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	353	Target Neighborhood Hits	204	Shared Neighborhood Hits	17
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

SWP70_HUMAN
NC score	0.052382 (rank : 368)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	353	Target Neighborhood Hits	973	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

RHG06_HUMAN
NC score	0.052179 (rank : 369)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	353	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG18_HUMAN
NC score	0.052139 (rank : 370)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	353	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

SWP70_MOUSE
NC score	0.052016 (rank : 371)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	353	Target Neighborhood Hits	1097	Shared Neighborhood Hits	83
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

DGKD_HUMAN
NC score	0.051799 (rank : 372)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	353	Target Neighborhood Hits	231	Shared Neighborhood Hits	35
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

RHG06_MOUSE
NC score	0.051669 (rank : 373)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	353	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

3BP1_HUMAN
NC score	0.051604 (rank : 374)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	353	Target Neighborhood Hits	376	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG12_MOUSE
NC score	0.051548 (rank : 375)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	353	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CD2AP_HUMAN
NC score	0.051258 (rank : 376)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	353	Target Neighborhood Hits	315	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

MYO9B_MOUSE
NC score	0.051241 (rank : 377)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	353	Target Neighborhood Hits	311	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

GRLF1_HUMAN
NC score	0.051034 (rank : 378)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	353	Target Neighborhood Hits	167	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

SH3G2_MOUSE
NC score	0.050787 (rank : 379)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	353	Target Neighborhood Hits	319	Shared Neighborhood Hits	25
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

TRPV2_MOUSE
NC score	0.050771 (rank : 380)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	353	Target Neighborhood Hits	111	Shared Neighborhood Hits	77
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

BSN_MOUSE
NC score	0.050279 (rank : 381)	θ value	0.279714 (rank : 187)
Query Neighborhood Hits	353	Target Neighborhood Hits	2057	Shared Neighborhood Hits	107
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NACAM_MOUSE
NC score	0.049601 (rank : 382)	θ value	2.36792 (rank : 268)
Query Neighborhood Hits	353	Target Neighborhood Hits	1866	Shared Neighborhood Hits	79
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

MTMRD_HUMAN
NC score	0.047698 (rank : 383)	θ value	3.0926 (rank : 278)
Query Neighborhood Hits	353	Target Neighborhood Hits	135	Shared Neighborhood Hits	32
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

CYH2_HUMAN
NC score	0.044997 (rank : 384)	θ value	6.88961 (rank : 328)
Query Neighborhood Hits	353	Target Neighborhood Hits	175	Shared Neighborhood Hits	32
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.044594 (rank : 385)	θ value	8.99809 (rank : 344)
Query Neighborhood Hits	353	Target Neighborhood Hits	171	Shared Neighborhood Hits	32
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

MAGE1_HUMAN
NC score	0.042955 (rank : 386)	θ value	0.0736092 (rank : 149)
Query Neighborhood Hits	353	Target Neighborhood Hits	1389	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

WASIP_MOUSE
NC score	0.042583 (rank : 387)	θ value	1.81305 (rank : 258)
Query Neighborhood Hits	353	Target Neighborhood Hits	392	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

SRRM2_HUMAN
NC score	0.039870 (rank : 388)	θ value	6.88961 (rank : 337)
Query Neighborhood Hits	353	Target Neighborhood Hits	1296	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRA1_HUMAN
NC score	0.038554 (rank : 389)	θ value	0.21417 (rank : 184)
Query Neighborhood Hits	353	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HD15, Q6NVU9, Q8IXM1, Q9HD13, Q9HD14	Gene names	SRA1
Domain Architecture	No domain graphic available
Description	Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP).

GAB2_MOUSE
NC score	0.037011 (rank : 390)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	353	Target Neighborhood Hits	220	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

OGFR_MOUSE
NC score	0.036868 (rank : 391)	θ value	3.0926 (rank : 281)
Query Neighborhood Hits	353	Target Neighborhood Hits	584	Shared Neighborhood Hits	28
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

TCOF_HUMAN
NC score	0.036641 (rank : 392)	θ value	0.21417 (rank : 185)
Query Neighborhood Hits	353	Target Neighborhood Hits	543	Shared Neighborhood Hits	32
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

MYH11_MOUSE
NC score	0.036297 (rank : 393)	θ value	0.0961366 (rank : 155)
Query Neighborhood Hits	353	Target Neighborhood Hits	1777	Shared Neighborhood Hits	80
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MTMR5_HUMAN
NC score	0.035997 (rank : 394)	θ value	1.81305 (rank : 250)
Query Neighborhood Hits	353	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MYH11_HUMAN
NC score	0.035771 (rank : 395)	θ value	0.0961366 (rank : 154)
Query Neighborhood Hits	353	Target Neighborhood Hits	1806	Shared Neighborhood Hits	80
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

SASH1_MOUSE
NC score	0.034734 (rank : 396)	θ value	1.38821 (rank : 240)
Query Neighborhood Hits	353	Target Neighborhood Hits	263	Shared Neighborhood Hits	22
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

FARP1_HUMAN
NC score	0.034300 (rank : 397)	θ value	0.47712 (rank : 204)
Query Neighborhood Hits	353	Target Neighborhood Hits	241	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

PK1L1_HUMAN
NC score	0.033738 (rank : 398)	θ value	0.125558 (rank : 170)
Query Neighborhood Hits	353	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

FGD6_HUMAN
NC score	0.033727 (rank : 399)	θ value	0.125558 (rank : 166)
Query Neighborhood Hits	353	Target Neighborhood Hits	237	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

MLL3_HUMAN
NC score	0.033395 (rank : 400)	θ value	0.21417 (rank : 181)
Query Neighborhood Hits	353	Target Neighborhood Hits	1644	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYH1_HUMAN
NC score	0.033361 (rank : 401)	θ value	0.365318 (rank : 195)
Query Neighborhood Hits	353	Target Neighborhood Hits	1478	Shared Neighborhood Hits	63
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH2_HUMAN
NC score	0.033348 (rank : 402)	θ value	0.62314 (rank : 214)
Query Neighborhood Hits	353	Target Neighborhood Hits	1491	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

CT2NL_MOUSE
NC score	0.033103 (rank : 403)	θ value	8.99809 (rank : 343)
Query Neighborhood Hits	353	Target Neighborhood Hits	902	Shared Neighborhood Hits	59
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

FYCO1_HUMAN
NC score	0.033093 (rank : 404)	θ value	0.62314 (rank : 212)
Query Neighborhood Hits	353	Target Neighborhood Hits	1149	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

MYH1_MOUSE
NC score	0.032725 (rank : 405)	θ value	1.81305 (rank : 252)
Query Neighborhood Hits	353	Target Neighborhood Hits	1461	Shared Neighborhood Hits	65
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH3_HUMAN
NC score	0.032632 (rank : 406)	θ value	1.38821 (rank : 239)
Query Neighborhood Hits	353	Target Neighborhood Hits	1660	Shared Neighborhood Hits	66
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH6_HUMAN
NC score	0.032477 (rank : 407)	θ value	5.27518 (rank : 312)
Query Neighborhood Hits	353	Target Neighborhood Hits	1426	Shared Neighborhood Hits	65
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

GOGB1_HUMAN
NC score	0.032453 (rank : 408)	θ value	0.47712 (rank : 205)
Query Neighborhood Hits	353	Target Neighborhood Hits	2297	Shared Neighborhood Hits	85
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MYH4_MOUSE
NC score	0.032318 (rank : 409)	θ value	4.03905 (rank : 296)
Query Neighborhood Hits	353	Target Neighborhood Hits	1476	Shared Neighborhood Hits	63
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_MOUSE
NC score	0.032307 (rank : 410)	θ value	4.03905 (rank : 298)
Query Neighborhood Hits	353	Target Neighborhood Hits	1600	Shared Neighborhood Hits	67
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH13_HUMAN
NC score	0.032168 (rank : 411)	θ value	3.0926 (rank : 279)
Query Neighborhood Hits	353	Target Neighborhood Hits	1504	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH10_MOUSE
NC score	0.032020 (rank : 412)	θ value	2.36792 (rank : 267)
Query Neighborhood Hits	353	Target Neighborhood Hits	1612	Shared Neighborhood Hits	73
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_HUMAN
NC score	0.031910 (rank : 413)	θ value	2.36792 (rank : 266)
Query Neighborhood Hits	353	Target Neighborhood Hits	1620	Shared Neighborhood Hits	71
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

IRS2_HUMAN
NC score	0.031883 (rank : 414)	θ value	1.81305 (rank : 249)
Query Neighborhood Hits	353	Target Neighborhood Hits	262	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

ZN291_HUMAN
NC score	0.031401 (rank : 415)	θ value	0.62314 (rank : 217)
Query Neighborhood Hits	353	Target Neighborhood Hits	647	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

MYH8_HUMAN
NC score	0.031230 (rank : 416)	θ value	4.03905 (rank : 297)
Query Neighborhood Hits	353	Target Neighborhood Hits	1610	Shared Neighborhood Hits	67
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

GOGA2_MOUSE
NC score	0.031152 (rank : 417)	θ value	1.06291 (rank : 227)
Query Neighborhood Hits	353	Target Neighborhood Hits	944	Shared Neighborhood Hits	51
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

CNTRB_MOUSE
NC score	0.030845 (rank : 418)	θ value	4.03905 (rank : 289)
Query Neighborhood Hits	353	Target Neighborhood Hits	1029	Shared Neighborhood Hits	62
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

GOGA3_MOUSE
NC score	0.030684 (rank : 419)	θ value	4.03905 (rank : 295)
Query Neighborhood Hits	353	Target Neighborhood Hits	1437	Shared Neighborhood Hits	68
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

TB182_HUMAN
NC score	0.030661 (rank : 420)	θ value	1.06291 (rank : 234)
Query Neighborhood Hits	353	Target Neighborhood Hits	414	Shared Neighborhood Hits	25
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

GOGA3_HUMAN
NC score	0.030050 (rank : 421)	θ value	4.03905 (rank : 294)
Query Neighborhood Hits	353	Target Neighborhood Hits	1317	Shared Neighborhood Hits	69
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

RBP24_HUMAN
NC score	0.029868 (rank : 422)	θ value	4.03905 (rank : 302)
Query Neighborhood Hits	353	Target Neighborhood Hits	1559	Shared Neighborhood Hits	72
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.029780 (rank : 423)	θ value	4.03905 (rank : 293)
Query Neighborhood Hits	353	Target Neighborhood Hits	1558	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

NFH_MOUSE
NC score	0.028539 (rank : 424)	θ value	0.0961366 (rank : 156)
Query Neighborhood Hits	353	Target Neighborhood Hits	2247	Shared Neighborhood Hits	107
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SSBP4_HUMAN
NC score	0.027916 (rank : 425)	θ value	0.47712 (rank : 207)
Query Neighborhood Hits	353	Target Neighborhood Hits	753	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

FGD4_HUMAN
NC score	0.027540 (rank : 426)	θ value	4.03905 (rank : 291)
Query Neighborhood Hits	353	Target Neighborhood Hits	219	Shared Neighborhood Hits	29
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

MYO5C_HUMAN
NC score	0.027280 (rank : 427)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	353	Target Neighborhood Hits	1206	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

ACINU_MOUSE
NC score	0.027158 (rank : 428)	θ value	4.03905 (rank : 286)
Query Neighborhood Hits	353	Target Neighborhood Hits	712	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

RAD50_MOUSE
NC score	0.026632 (rank : 429)	θ value	1.81305 (rank : 257)
Query Neighborhood Hits	353	Target Neighborhood Hits	1366	Shared Neighborhood Hits	56
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

TENS4_MOUSE
NC score	0.026509 (rank : 430)	θ value	0.62314 (rank : 216)
Query Neighborhood Hits	353	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

NIN_HUMAN
NC score	0.026403 (rank : 431)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	353	Target Neighborhood Hits	1416	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

AIM1_HUMAN
NC score	0.025983 (rank : 432)	θ value	0.125558 (rank : 161)
Query Neighborhood Hits	353	Target Neighborhood Hits	247	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

TM108_HUMAN
NC score	0.024903 (rank : 433)	θ value	3.0926 (rank : 284)
Query Neighborhood Hits	353	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

GOGA1_MOUSE
NC score	0.023888 (rank : 434)	θ value	8.99809 (rank : 346)
Query Neighborhood Hits	353	Target Neighborhood Hits	994	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

DISC1_HUMAN
NC score	0.022726 (rank : 435)	θ value	4.03905 (rank : 290)
Query Neighborhood Hits	353	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NRI5, O75045, Q5VT44, Q5VT45, Q8IXJ0, Q8IXJ1, Q9BX19, Q9NRI3, Q9NRI4	Gene names	DISC1, KIAA0457
Domain Architecture	No domain graphic available
Description	Disrupted in schizophrenia 1 protein.

MAVS_HUMAN
NC score	0.022444 (rank : 436)	θ value	5.27518 (rank : 311)
Query Neighborhood Hits	353	Target Neighborhood Hits	271	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

ZN750_MOUSE
NC score	0.021038 (rank : 437)	θ value	6.88961 (rank : 339)
Query Neighborhood Hits	353	Target Neighborhood Hits	346	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

AKAP2_MOUSE
NC score	0.017678 (rank : 438)	θ value	6.88961 (rank : 320)
Query Neighborhood Hits	353	Target Neighborhood Hits	385	Shared Neighborhood Hits	21
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

RECQ5_HUMAN
NC score	0.017479 (rank : 439)	θ value	1.06291 (rank : 233)
Query Neighborhood Hits	353	Target Neighborhood Hits	390	Shared Neighborhood Hits	24
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

MEF2B_HUMAN
NC score	0.016706 (rank : 440)	θ value	2.36792 (rank : 265)
Query Neighborhood Hits	353	Target Neighborhood Hits	150	Shared Neighborhood Hits	6
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

AKAP1_MOUSE
NC score	0.015328 (rank : 441)	θ value	2.36792 (rank : 261)
Query Neighborhood Hits	353	Target Neighborhood Hits	198	Shared Neighborhood Hits	10
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

NOL9_HUMAN
NC score	0.014476 (rank : 442)	θ value	5.27518 (rank : 313)
Query Neighborhood Hits	353	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SY16, Q4VBY3, Q6P472, Q7L4D6, Q96EE0, Q9H5L4	Gene names	NOL9
Domain Architecture	No domain graphic available
Description	Nucleolar protein 9.

ELOA3_HUMAN
NC score	0.012423 (rank : 443)	θ value	5.27518 (rank : 310)
Query Neighborhood Hits	353	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

SGOL1_MOUSE
NC score	0.011534 (rank : 444)	θ value	5.27518 (rank : 317)
Query Neighborhood Hits	353	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CXH7, Q3U4K4, Q588H1, Q8BKW2	Gene names	Sgol1, Sgo1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1.

CB017_MOUSE
NC score	0.011479 (rank : 445)	θ value	6.88961 (rank : 326)
Query Neighborhood Hits	353	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q6NS82, Q3TA48, Q8BSD3, Q8CHY1, Q8R0Q3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17 homolog.

HUWE1_HUMAN
NC score	0.010542 (rank : 446)	θ value	8.99809 (rank : 348)
Query Neighborhood Hits	353	Target Neighborhood Hits	443	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

CSPG2_MOUSE
NC score	0.010056 (rank : 447)	θ value	5.27518 (rank : 309)
Query Neighborhood Hits	353	Target Neighborhood Hits	711	Shared Neighborhood Hits	30
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

DCP1B_HUMAN
NC score	0.009813 (rank : 448)	θ value	6.88961 (rank : 329)
Query Neighborhood Hits	353	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

COBA1_MOUSE
NC score	0.008856 (rank : 449)	θ value	1.81305 (rank : 247)
Query Neighborhood Hits	353	Target Neighborhood Hits	487	Shared Neighborhood Hits	25
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_HUMAN
NC score	0.007772 (rank : 450)	θ value	6.88961 (rank : 327)
Query Neighborhood Hits	353	Target Neighborhood Hits	491	Shared Neighborhood Hits	23
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

MYLK_MOUSE
NC score	0.007210 (rank : 451)	θ value	0.125558 (rank : 168)
Query Neighborhood Hits	353	Target Neighborhood Hits	1489	Shared Neighborhood Hits	46
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

TBC12_HUMAN
NC score	0.006852 (rank : 452)	θ value	4.03905 (rank : 304)
Query Neighborhood Hits	353	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

APBA2_MOUSE
NC score	0.006040 (rank : 453)	θ value	6.88961 (rank : 323)
Query Neighborhood Hits	353	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

ARHGB_HUMAN
NC score	0.005608 (rank : 454)	θ value	6.88961 (rank : 324)
Query Neighborhood Hits	353	Target Neighborhood Hits	375	Shared Neighborhood Hits	13
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

ITCH_HUMAN
NC score	0.005573 (rank : 455)	θ value	6.88961 (rank : 332)
Query Neighborhood Hits	353	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

SPEG_HUMAN
NC score	0.004755 (rank : 456)	θ value	0.365318 (rank : 197)
Query Neighborhood Hits	353	Target Neighborhood Hits	1762	Shared Neighborhood Hits	47
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SEZ6L_HUMAN
NC score	0.004302 (rank : 457)	θ value	8.99809 (rank : 351)
Query Neighborhood Hits	353	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

GP123_HUMAN
NC score	0.004184 (rank : 458)	θ value	8.99809 (rank : 347)
Query Neighborhood Hits	353	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

MAST1_MOUSE
NC score	0.003395 (rank : 459)	θ value	0.163984 (rank : 177)
Query Neighborhood Hits	353	Target Neighborhood Hits	1123	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

FOG1_MOUSE
NC score	0.000809 (rank : 460)	θ value	8.99809 (rank : 345)
Query Neighborhood Hits	353	Target Neighborhood Hits	1237	Shared Neighborhood Hits	38
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HGFA_MOUSE
NC score	0.000772 (rank : 461)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	353	Target Neighborhood Hits	419	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

FOG1_HUMAN
NC score	-0.001572 (rank : 462)	θ value	4.03905 (rank : 292)
Query Neighborhood Hits	353	Target Neighborhood Hits	981	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

ZFHX2_HUMAN
NC score	-0.002483 (rank : 463)	θ value	5.27518 (rank : 318)
Query Neighborhood Hits	353	Target Neighborhood Hits	1178	Shared Neighborhood Hits	22
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

PRTN3_HUMAN
NC score	-0.002509 (rank : 464)	θ value	8.99809 (rank : 350)
Query Neighborhood Hits	353	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P24158, P15637, P18078, Q6LBM7, Q9UQD8	Gene names	PRTN3, MBN
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Leukocyte proteinase 3) (PR-3) (PR3) (AGP7) (Wegener autoantigen) (P29) (C-ANCA antigen) (Neutrophil proteinase 4) (NP-4).

ZN447_HUMAN
NC score	-0.003063 (rank : 465)	θ value	1.81305 (rank : 260)
Query Neighborhood Hits	353	Target Neighborhood Hits	899	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

TMPS4_MOUSE
NC score	-0.003068 (rank : 466)	θ value	8.99809 (rank : 352)
Query Neighborhood Hits	353	Target Neighborhood Hits	210	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

HXB1_HUMAN
NC score	-0.004149 (rank : 467)	θ value	8.99809 (rank : 349)
Query Neighborhood Hits	353	Target Neighborhood Hits	356	Shared Neighborhood Hits	4
SwissProt Accessions	P14653	Gene names	HOXB1, HOX2I
Domain Architecture
Description	Homeobox protein Hox-B1 (Hox-2I).

ZN418_HUMAN
NC score	-0.009166 (rank : 468)	θ value	8.99809 (rank : 353)
Query Neighborhood Hits	353	Target Neighborhood Hits	776	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TF45, Q670L5, Q96N18	Gene names	ZNF418, KIAA1956
Domain Architecture
Description	Zinc finger protein 418.