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Network neighborhood for query Sequence : OSBL3_MOUSE

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OSBL3_MOUSE
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OSBL3_HUMAN
θ value	0 (rank : 1)	NC score	0.995133 (rank : 2)
Query Neighborhood Hits	86	Target Neighborhood Hits	93	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL6_HUMAN
θ value	0 (rank : 3)	NC score	0.984798 (rank : 3)
Query Neighborhood Hits	86	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_MOUSE
θ value	0 (rank : 4)	NC score	0.982845 (rank : 5)
Query Neighborhood Hits	86	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL7_HUMAN
θ value	0 (rank : 5)	NC score	0.984139 (rank : 4)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBP1_HUMAN
θ value	3.23591e-74 (rank : 6)	NC score	0.889397 (rank : 10)
Query Neighborhood Hits	86	Target Neighborhood Hits	180	Shared Neighborhood Hits	50
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBP2_HUMAN
θ value	2.09745e-73 (rank : 7)	NC score	0.893588 (rank : 9)
Query Neighborhood Hits	86	Target Neighborhood Hits	154	Shared Neighborhood Hits	48
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBL1_HUMAN
θ value	5.1662e-72 (rank : 8)	NC score	0.624015 (rank : 19)
Query Neighborhood Hits	86	Target Neighborhood Hits	368	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_MOUSE
θ value	8.81223e-72 (rank : 9)	NC score	0.637580 (rank : 17)
Query Neighborhood Hits	86	Target Neighborhood Hits	336	Shared Neighborhood Hits	35
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBP2_MOUSE
θ value	5.71191e-71 (rank : 10)	NC score	0.895243 (rank : 8)
Query Neighborhood Hits	86	Target Neighborhood Hits	150	Shared Neighborhood Hits	45
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBL2_HUMAN
θ value	2.3998e-69 (rank : 11)	NC score	0.917138 (rank : 6)
Query Neighborhood Hits	86	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_MOUSE
θ value	9.78833e-55 (rank : 12)	NC score	0.911191 (rank : 7)
Query Neighborhood Hits	86	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL5_HUMAN
θ value	1.5773e-20 (rank : 13)	NC score	0.696496 (rank : 11)
Query Neighborhood Hits	86	Target Neighborhood Hits	117	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL8_HUMAN
θ value	2.27762e-19 (rank : 14)	NC score	0.677022 (rank : 13)
Query Neighborhood Hits	86	Target Neighborhood Hits	289	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSBL5_MOUSE
θ value	6.62687e-19 (rank : 15)	NC score	0.695458 (rank : 12)
Query Neighborhood Hits	86	Target Neighborhood Hits	77	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL9_HUMAN
θ value	1.38178e-16 (rank : 16)	NC score	0.661858 (rank : 15)
Query Neighborhood Hits	86	Target Neighborhood Hits	138	Shared Neighborhood Hits	43
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSB10_HUMAN
θ value	4.02038e-16 (rank : 17)	NC score	0.667995 (rank : 14)
Query Neighborhood Hits	86	Target Neighborhood Hits	55	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSB11_MOUSE
θ value	7.58209e-15 (rank : 18)	NC score	0.639131 (rank : 16)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB11_HUMAN
θ value	1.42992e-13 (rank : 19)	NC score	0.628636 (rank : 18)
Query Neighborhood Hits	86	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

DDEF1_MOUSE
θ value	0.000121331 (rank : 20)	NC score	0.137414 (rank : 24)
Query Neighborhood Hits	86	Target Neighborhood Hits	592	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

C43BP_MOUSE
θ value	0.000786445 (rank : 21)	NC score	0.331458 (rank : 23)
Query Neighborhood Hits	86	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_HUMAN
θ value	0.00228821 (rank : 22)	NC score	0.334525 (rank : 22)
Query Neighborhood Hits	86	Target Neighborhood Hits	87	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

DDEF2_HUMAN
θ value	0.0252991 (rank : 23)	NC score	0.099468 (rank : 25)
Query Neighborhood Hits	86	Target Neighborhood Hits	599	Shared Neighborhood Hits	27
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	0.0330416 (rank : 24)	NC score	0.098657 (rank : 26)
Query Neighborhood Hits	86	Target Neighborhood Hits	625	Shared Neighborhood Hits	30
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DGKH_HUMAN
θ value	0.0431538 (rank : 25)	NC score	0.038778 (rank : 64)
Query Neighborhood Hits	86	Target Neighborhood Hits	255	Shared Neighborhood Hits	27
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

RYR3_HUMAN
θ value	0.0431538 (rank : 26)	NC score	0.025363 (rank : 69)
Query Neighborhood Hits	86	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

DDFL1_HUMAN
θ value	0.0563607 (rank : 27)	NC score	0.088133 (rank : 29)
Query Neighborhood Hits	86	Target Neighborhood Hits	353	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

IP3KC_MOUSE
θ value	0.0563607 (rank : 28)	NC score	0.037343 (rank : 65)
Query Neighborhood Hits	86	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TS72, Q3U384	Gene names	Itpkc
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (IP3K-C).

MYO10_HUMAN
θ value	0.0563607 (rank : 29)	NC score	0.053093 (rank : 55)
Query Neighborhood Hits	86	Target Neighborhood Hits	920	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

CYH2_HUMAN
θ value	0.125558 (rank : 30)	NC score	0.076397 (rank : 33)
Query Neighborhood Hits	86	Target Neighborhood Hits	175	Shared Neighborhood Hits	36
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	0.125558 (rank : 31)	NC score	0.076354 (rank : 34)
Query Neighborhood Hits	86	Target Neighborhood Hits	171	Shared Neighborhood Hits	36
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_HUMAN
θ value	0.125558 (rank : 32)	NC score	0.076602 (rank : 32)
Query Neighborhood Hits	86	Target Neighborhood Hits	137	Shared Neighborhood Hits	32
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

DDFL1_MOUSE
θ value	0.125558 (rank : 33)	NC score	0.086987 (rank : 30)
Query Neighborhood Hits	86	Target Neighborhood Hits	324	Shared Neighborhood Hits	24
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

SPAT7_HUMAN
θ value	0.125558 (rank : 34)	NC score	0.042478 (rank : 62)
Query Neighborhood Hits	86	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0W8, Q8WX30, Q96HF3, Q9H0X0, Q9P0W7	Gene names	SPATA7, HSD3
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 7 (Spermatogenesis-associated protein HSD3) (HSD-3.1).

CYH1_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.075536 (rank : 36)
Query Neighborhood Hits	86	Target Neighborhood Hits	184	Shared Neighborhood Hits	38
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

GIT1_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.040360 (rank : 63)
Query Neighborhood Hits	86	Target Neighborhood Hits	336	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

MTMRD_HUMAN
θ value	0.365318 (rank : 37)	NC score	0.075937 (rank : 35)
Query Neighborhood Hits	86	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

PKHA2_MOUSE
θ value	0.365318 (rank : 38)	NC score	0.075464 (rank : 37)
Query Neighborhood Hits	86	Target Neighborhood Hits	116	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

CYH1_MOUSE
θ value	0.47712 (rank : 39)	NC score	0.074127 (rank : 38)
Query Neighborhood Hits	86	Target Neighborhood Hits	176	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

PKHA3_HUMAN
θ value	0.47712 (rank : 40)	NC score	0.347492 (rank : 21)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_MOUSE
θ value	0.62314 (rank : 41)	NC score	0.353745 (rank : 20)
Query Neighborhood Hits	86	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

GAB2_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.066021 (rank : 46)
Query Neighborhood Hits	86	Target Neighborhood Hits	188	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GAB1_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.050433 (rank : 59)
Query Neighborhood Hits	86	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.049166 (rank : 61)
Query Neighborhood Hits	86	Target Neighborhood Hits	233	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

RHG25_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.064707 (rank : 49)
Query Neighborhood Hits	86	Target Neighborhood Hits	550	Shared Neighborhood Hits	47
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.066288 (rank : 45)
Query Neighborhood Hits	86	Target Neighborhood Hits	492	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RRBP1_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.009348 (rank : 77)
Query Neighborhood Hits	86	Target Neighborhood Hits	1306	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

CYH3_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.082033 (rank : 31)
Query Neighborhood Hits	86	Target Neighborhood Hits	148	Shared Neighborhood Hits	38
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH4_MOUSE
θ value	2.36792 (rank : 49)	NC score	0.091514 (rank : 27)
Query Neighborhood Hits	86	Target Neighborhood Hits	134	Shared Neighborhood Hits	38
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

DISC1_MOUSE
θ value	2.36792 (rank : 50)	NC score	0.016567 (rank : 71)
Query Neighborhood Hits	86	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	Q811T9, Q7TQ21, Q8CF87, Q8CF88, Q8CHP1, Q8CHP2	Gene names	Disc1
Domain Architecture	No domain graphic available
Description	Disrupted in schizophrenia 1 homolog.

CENB5_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.063994 (rank : 50)
Query Neighborhood Hits	86	Target Neighborhood Hits	395	Shared Neighborhood Hits	42
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

RHG06_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.010242 (rank : 76)
Query Neighborhood Hits	86	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

ACTN4_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.005631 (rank : 85)
Query Neighborhood Hits	86	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.005573 (rank : 86)
Query Neighborhood Hits	86	Target Neighborhood Hits	276	Shared Neighborhood Hits	7
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ANR26_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.015603 (rank : 72)
Query Neighborhood Hits	86	Target Neighborhood Hits	1614	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CYH4_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.089856 (rank : 28)
Query Neighborhood Hits	86	Target Neighborhood Hits	135	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYTSA_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.006419 (rank : 82)
Query Neighborhood Hits	86	Target Neighborhood Hits	1104	Shared Neighborhood Hits	23
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

GIT1_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.036462 (rank : 66)
Query Neighborhood Hits	86	Target Neighborhood Hits	341	Shared Neighborhood Hits	16
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

LIPA1_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.011101 (rank : 74)
Query Neighborhood Hits	86	Target Neighborhood Hits	1294	Shared Neighborhood Hits	21
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LRCH1_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.006153 (rank : 83)
Query Neighborhood Hits	86	Target Neighborhood Hits	266	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2L9, Q7Z5F6, Q7Z5F7	Gene names	LRCH1, CHDC1, KIAA1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81).

LRCH1_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.006149 (rank : 84)
Query Neighborhood Hits	86	Target Neighborhood Hits	264	Shared Neighborhood Hits	3
SwissProt Accessions	P62046	Gene names	Lrch1, Chdc1, Kiaa1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1).

PKHA2_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.069355 (rank : 41)
Query Neighborhood Hits	86	Target Neighborhood Hits	119	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PRDM2_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.007888 (rank : 79)
Query Neighborhood Hits	86	Target Neighborhood Hits	1135	Shared Neighborhood Hits	8
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SWP70_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.069477 (rank : 40)
Query Neighborhood Hits	86	Target Neighborhood Hits	1097	Shared Neighborhood Hits	59
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

BAT4_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.020132 (rank : 70)
Query Neighborhood Hits	86	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CENB1_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.062556 (rank : 51)
Query Neighborhood Hits	86	Target Neighborhood Hits	383	Shared Neighborhood Hits	42
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DAAM2_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.008043 (rank : 78)
Query Neighborhood Hits	86	Target Neighborhood Hits	350	Shared Neighborhood Hits	10
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

MYO5A_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.004551 (rank : 90)
Query Neighborhood Hits	86	Target Neighborhood Hits	1092	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

PKHA1_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.066883 (rank : 42)
Query Neighborhood Hits	86	Target Neighborhood Hits	127	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

RBM25_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.005538 (rank : 87)
Query Neighborhood Hits	86	Target Neighborhood Hits	682	Shared Neighborhood Hits	12
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RIC8B_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.012058 (rank : 73)
Query Neighborhood Hits	86	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVN3, Q4G103, Q6ZRN4, Q86WD3	Gene names	RIC8B
Domain Architecture	No domain graphic available
Description	Synembryn-B (Brain synembrin) (hSyn) (Protein Ric-8B).

SWP70_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.072427 (rank : 39)
Query Neighborhood Hits	86	Target Neighborhood Hits	973	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TARA_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.029444 (rank : 67)
Query Neighborhood Hits	86	Target Neighborhood Hits	1626	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARA_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.050174 (rank : 60)
Query Neighborhood Hits	86	Target Neighborhood Hits	1133	Shared Neighborhood Hits	44
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DAAM2_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.007404 (rank : 80)
Query Neighborhood Hits	86	Target Neighborhood Hits	371	Shared Neighborhood Hits	9
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

DAPP1_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.051965 (rank : 57)
Query Neighborhood Hits	86	Target Neighborhood Hits	225	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

FARP1_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.025973 (rank : 68)
Query Neighborhood Hits	86	Target Neighborhood Hits	241	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

NBEA_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.004132 (rank : 91)
Query Neighborhood Hits	86	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

SENP1_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.006716 (rank : 81)
Query Neighborhood Hits	86	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

ZN292_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.002070 (rank : 94)
Query Neighborhood Hits	86	Target Neighborhood Hits	918	Shared Neighborhood Hits	3
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

ARTS1_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.004899 (rank : 88)
Query Neighborhood Hits	86	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZ08, O60278, Q6UWY6, Q8NEL4, Q8TAD0, Q9UHF8, Q9UKY2	Gene names	ARTS1, APPILS, KIAA0525
Domain Architecture
Description	Adipocyte-derived leucine aminopeptidase precursor (EC 3.4.11.-) (A- LAP) (ARTS-1) (Aminopeptidase PILS) (Puromycin-insensitive leucyl- specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator).

CAR15_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.003687 (rank : 92)
Query Neighborhood Hits	86	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

CING_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.001941 (rank : 95)
Query Neighborhood Hits	86	Target Neighborhood Hits	1432	Shared Neighborhood Hits	20
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

OFD1_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.004634 (rank : 89)
Query Neighborhood Hits	86	Target Neighborhood Hits	753	Shared Neighborhood Hits	17
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

RIC8B_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.010377 (rank : 75)
Query Neighborhood Hits	86	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XE1, Q58L65	Gene names	Ric8b
Domain Architecture	No domain graphic available
Description	Synembryn-B (Protein Ric-8B).

TRHY_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.003500 (rank : 93)
Query Neighborhood Hits	86	Target Neighborhood Hits	1385	Shared Neighborhood Hits	19
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

GAB2_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.066425 (rank : 43)
Query Neighborhood Hits	86	Target Neighborhood Hits	220	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

PKHA1_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.057452 (rank : 53)
Query Neighborhood Hits	86	Target Neighborhood Hits	120	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA6_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.065819 (rank : 47)
Query Neighborhood Hits	86	Target Neighborhood Hits	556	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.060087 (rank : 52)
Query Neighborhood Hits	86	Target Neighborhood Hits	591	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK2_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.065124 (rank : 48)
Query Neighborhood Hits	86	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.066370 (rank : 44)
Query Neighborhood Hits	86	Target Neighborhood Hits	96	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.052251 (rank : 56)
Query Neighborhood Hits	86	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.054129 (rank : 54)
Query Neighborhood Hits	86	Target Neighborhood Hits	109	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

TBCD2_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.050989 (rank : 58)
Query Neighborhood Hits	86	Target Neighborhood Hits	419	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

Hits sorted by NC score

OSBL3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL3_HUMAN
NC score	0.995133 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	86	Target Neighborhood Hits	93	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL6_HUMAN
NC score	0.984798 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	86	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL7_HUMAN
NC score	0.984139 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBL6_MOUSE
NC score	0.982845 (rank : 5)	θ value	0 (rank : 4)
Query Neighborhood Hits	86	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL2_HUMAN
NC score	0.917138 (rank : 6)	θ value	2.3998e-69 (rank : 11)
Query Neighborhood Hits	86	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_MOUSE
NC score	0.911191 (rank : 7)	θ value	9.78833e-55 (rank : 12)
Query Neighborhood Hits	86	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBP2_MOUSE
NC score	0.895243 (rank : 8)	θ value	5.71191e-71 (rank : 10)
Query Neighborhood Hits	86	Target Neighborhood Hits	150	Shared Neighborhood Hits	45
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBP2_HUMAN
NC score	0.893588 (rank : 9)	θ value	2.09745e-73 (rank : 7)
Query Neighborhood Hits	86	Target Neighborhood Hits	154	Shared Neighborhood Hits	48
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP1_HUMAN
NC score	0.889397 (rank : 10)	θ value	3.23591e-74 (rank : 6)
Query Neighborhood Hits	86	Target Neighborhood Hits	180	Shared Neighborhood Hits	50
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBL5_HUMAN
NC score	0.696496 (rank : 11)	θ value	1.5773e-20 (rank : 13)
Query Neighborhood Hits	86	Target Neighborhood Hits	117	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL5_MOUSE
NC score	0.695458 (rank : 12)	θ value	6.62687e-19 (rank : 15)
Query Neighborhood Hits	86	Target Neighborhood Hits	77	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSBL8_HUMAN
NC score	0.677022 (rank : 13)	θ value	2.27762e-19 (rank : 14)
Query Neighborhood Hits	86	Target Neighborhood Hits	289	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSB10_HUMAN
NC score	0.667995 (rank : 14)	θ value	4.02038e-16 (rank : 17)
Query Neighborhood Hits	86	Target Neighborhood Hits	55	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSBL9_HUMAN
NC score	0.661858 (rank : 15)	θ value	1.38178e-16 (rank : 16)
Query Neighborhood Hits	86	Target Neighborhood Hits	138	Shared Neighborhood Hits	43
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSB11_MOUSE
NC score	0.639131 (rank : 16)	θ value	7.58209e-15 (rank : 18)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL1_MOUSE
NC score	0.637580 (rank : 17)	θ value	8.81223e-72 (rank : 9)
Query Neighborhood Hits	86	Target Neighborhood Hits	336	Shared Neighborhood Hits	35
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSB11_HUMAN
NC score	0.628636 (rank : 18)	θ value	1.42992e-13 (rank : 19)
Query Neighborhood Hits	86	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL1_HUMAN
NC score	0.624015 (rank : 19)	θ value	5.1662e-72 (rank : 8)
Query Neighborhood Hits	86	Target Neighborhood Hits	368	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PKHA3_MOUSE
NC score	0.353745 (rank : 20)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	86	Target Neighborhood Hits	67	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHA3_HUMAN
NC score	0.347492 (rank : 21)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

C43BP_HUMAN
NC score	0.334525 (rank : 22)	θ value	0.00228821 (rank : 22)
Query Neighborhood Hits	86	Target Neighborhood Hits	87	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

C43BP_MOUSE
NC score	0.331458 (rank : 23)	θ value	0.000786445 (rank : 21)
Query Neighborhood Hits	86	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

DDEF1_MOUSE
NC score	0.137414 (rank : 24)	θ value	0.000121331 (rank : 20)
Query Neighborhood Hits	86	Target Neighborhood Hits	592	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
NC score	0.099468 (rank : 25)	θ value	0.0252991 (rank : 23)
Query Neighborhood Hits	86	Target Neighborhood Hits	599	Shared Neighborhood Hits	27
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.098657 (rank : 26)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	86	Target Neighborhood Hits	625	Shared Neighborhood Hits	30
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CYH4_MOUSE
NC score	0.091514 (rank : 27)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	86	Target Neighborhood Hits	134	Shared Neighborhood Hits	38
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
NC score	0.089856 (rank : 28)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	86	Target Neighborhood Hits	135	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

DDFL1_HUMAN
NC score	0.088133 (rank : 29)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	86	Target Neighborhood Hits	353	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
NC score	0.086987 (rank : 30)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	86	Target Neighborhood Hits	324	Shared Neighborhood Hits	24
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

CYH3_MOUSE
NC score	0.082033 (rank : 31)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	86	Target Neighborhood Hits	148	Shared Neighborhood Hits	38
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH3_HUMAN
NC score	0.076602 (rank : 32)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	86	Target Neighborhood Hits	137	Shared Neighborhood Hits	32
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH2_HUMAN
NC score	0.076397 (rank : 33)	θ value	0.125558 (rank : 30)
Query Neighborhood Hits	86	Target Neighborhood Hits	175	Shared Neighborhood Hits	36
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.076354 (rank : 34)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	86	Target Neighborhood Hits	171	Shared Neighborhood Hits	36
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

MTMRD_HUMAN
NC score	0.075937 (rank : 35)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	86	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

CYH1_HUMAN
NC score	0.075536 (rank : 36)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	86	Target Neighborhood Hits	184	Shared Neighborhood Hits	38
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

PKHA2_MOUSE
NC score	0.075464 (rank : 37)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	86	Target Neighborhood Hits	116	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

CYH1_MOUSE
NC score	0.074127 (rank : 38)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	86	Target Neighborhood Hits	176	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

SWP70_HUMAN
NC score	0.072427 (rank : 39)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	86	Target Neighborhood Hits	973	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
NC score	0.069477 (rank : 40)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	86	Target Neighborhood Hits	1097	Shared Neighborhood Hits	59
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PKHA2_HUMAN
NC score	0.069355 (rank : 41)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	86	Target Neighborhood Hits	119	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA1_HUMAN
NC score	0.066883 (rank : 42)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	86	Target Neighborhood Hits	127	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

GAB2_MOUSE
NC score	0.066425 (rank : 43)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	86	Target Neighborhood Hits	220	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

PLEK2_MOUSE
NC score	0.066370 (rank : 44)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	86	Target Neighborhood Hits	96	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

RHG25_MOUSE
NC score	0.066288 (rank : 45)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	86	Target Neighborhood Hits	492	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

GAB2_HUMAN
NC score	0.066021 (rank : 46)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	86	Target Neighborhood Hits	188	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

PKHA6_HUMAN
NC score	0.065819 (rank : 47)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	86	Target Neighborhood Hits	556	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK2_HUMAN
NC score	0.065124 (rank : 48)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	86	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

RHG25_HUMAN
NC score	0.064707 (rank : 49)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	86	Target Neighborhood Hits	550	Shared Neighborhood Hits	47
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CENB5_HUMAN
NC score	0.063994 (rank : 50)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	86	Target Neighborhood Hits	395	Shared Neighborhood Hits	42
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB1_HUMAN
NC score	0.062556 (rank : 51)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	86	Target Neighborhood Hits	383	Shared Neighborhood Hits	42
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

PKHA6_MOUSE
NC score	0.060087 (rank : 52)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	86	Target Neighborhood Hits	591	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA1_MOUSE
NC score	0.057452 (rank : 53)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	86	Target Neighborhood Hits	120	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLEK_MOUSE
NC score	0.054129 (rank : 54)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	86	Target Neighborhood Hits	109	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

MYO10_HUMAN
NC score	0.053093 (rank : 55)	θ value	0.0563607 (rank : 29)
Query Neighborhood Hits	86	Target Neighborhood Hits	920	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PLEK_HUMAN
NC score	0.052251 (rank : 56)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	86	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

DAPP1_MOUSE
NC score	0.051965 (rank : 57)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	86	Target Neighborhood Hits	225	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

TBCD2_HUMAN
NC score	0.050989 (rank : 58)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	86	Target Neighborhood Hits	419	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

GAB1_HUMAN
NC score	0.050433 (rank : 59)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	86	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

TARA_MOUSE
NC score	0.050174 (rank : 60)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	86	Target Neighborhood Hits	1133	Shared Neighborhood Hits	44
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

GAB1_MOUSE
NC score	0.049166 (rank : 61)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	86	Target Neighborhood Hits	233	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

SPAT7_HUMAN
NC score	0.042478 (rank : 62)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	86	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0W8, Q8WX30, Q96HF3, Q9H0X0, Q9P0W7	Gene names	SPATA7, HSD3
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 7 (Spermatogenesis-associated protein HSD3) (HSD-3.1).

GIT1_HUMAN
NC score	0.040360 (rank : 63)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	86	Target Neighborhood Hits	336	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

DGKH_HUMAN
NC score	0.038778 (rank : 64)	θ value	0.0431538 (rank : 25)
Query Neighborhood Hits	86	Target Neighborhood Hits	255	Shared Neighborhood Hits	27
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

IP3KC_MOUSE
NC score	0.037343 (rank : 65)	θ value	0.0563607 (rank : 28)
Query Neighborhood Hits	86	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TS72, Q3U384	Gene names	Itpkc
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (IP3K-C).

GIT1_MOUSE
NC score	0.036462 (rank : 66)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	86	Target Neighborhood Hits	341	Shared Neighborhood Hits	16
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

TARA_HUMAN
NC score	0.029444 (rank : 67)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	86	Target Neighborhood Hits	1626	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

FARP1_HUMAN
NC score	0.025973 (rank : 68)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	86	Target Neighborhood Hits	241	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

RYR3_HUMAN
NC score	0.025363 (rank : 69)	θ value	0.0431538 (rank : 26)
Query Neighborhood Hits	86	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

BAT4_HUMAN
NC score	0.020132 (rank : 70)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	86	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

DISC1_MOUSE
NC score	0.016567 (rank : 71)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	86	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	Q811T9, Q7TQ21, Q8CF87, Q8CF88, Q8CHP1, Q8CHP2	Gene names	Disc1
Domain Architecture	No domain graphic available
Description	Disrupted in schizophrenia 1 homolog.

ANR26_HUMAN
NC score	0.015603 (rank : 72)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	86	Target Neighborhood Hits	1614	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

RIC8B_HUMAN
NC score	0.012058 (rank : 73)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	86	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVN3, Q4G103, Q6ZRN4, Q86WD3	Gene names	RIC8B
Domain Architecture	No domain graphic available
Description	Synembryn-B (Brain synembrin) (hSyn) (Protein Ric-8B).

LIPA1_HUMAN
NC score	0.011101 (rank : 74)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	86	Target Neighborhood Hits	1294	Shared Neighborhood Hits	21
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

RIC8B_MOUSE
NC score	0.010377 (rank : 75)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	86	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XE1, Q58L65	Gene names	Ric8b
Domain Architecture	No domain graphic available
Description	Synembryn-B (Protein Ric-8B).

RHG06_HUMAN
NC score	0.010242 (rank : 76)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	86	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RRBP1_HUMAN
NC score	0.009348 (rank : 77)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	86	Target Neighborhood Hits	1306	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

DAAM2_HUMAN
NC score	0.008043 (rank : 78)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	86	Target Neighborhood Hits	350	Shared Neighborhood Hits	10
SwissProt Accessions	Q86T65, Q5T4U0, Q9NQI5, Q9Y4G0	Gene names	DAAM2, KIAA0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

PRDM2_HUMAN
NC score	0.007888 (rank : 79)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	86	Target Neighborhood Hits	1135	Shared Neighborhood Hits	8
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

DAAM2_MOUSE
NC score	0.007404 (rank : 80)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	86	Target Neighborhood Hits	371	Shared Neighborhood Hits	9
SwissProt Accessions	Q80U19, Q810J5	Gene names	Daam2, Kiaa0381
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 2.

SENP1_HUMAN
NC score	0.006716 (rank : 81)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	86	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

CYTSA_MOUSE
NC score	0.006419 (rank : 82)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	86	Target Neighborhood Hits	1104	Shared Neighborhood Hits	23
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

LRCH1_HUMAN
NC score	0.006153 (rank : 83)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	86	Target Neighborhood Hits	266	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2L9, Q7Z5F6, Q7Z5F7	Gene names	LRCH1, CHDC1, KIAA1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81).

LRCH1_MOUSE
NC score	0.006149 (rank : 84)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	86	Target Neighborhood Hits	264	Shared Neighborhood Hits	3
SwissProt Accessions	P62046	Gene names	Lrch1, Chdc1, Kiaa1016
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1).

ACTN4_HUMAN
NC score	0.005631 (rank : 85)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	86	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
NC score	0.005573 (rank : 86)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	86	Target Neighborhood Hits	276	Shared Neighborhood Hits	7
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

RBM25_HUMAN
NC score	0.005538 (rank : 87)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	86	Target Neighborhood Hits	682	Shared Neighborhood Hits	12
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

ARTS1_HUMAN
NC score	0.004899 (rank : 88)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	86	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZ08, O60278, Q6UWY6, Q8NEL4, Q8TAD0, Q9UHF8, Q9UKY2	Gene names	ARTS1, APPILS, KIAA0525
Domain Architecture
Description	Adipocyte-derived leucine aminopeptidase precursor (EC 3.4.11.-) (A- LAP) (ARTS-1) (Aminopeptidase PILS) (Puromycin-insensitive leucyl- specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator).

OFD1_HUMAN
NC score	0.004634 (rank : 89)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	86	Target Neighborhood Hits	753	Shared Neighborhood Hits	17
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

MYO5A_HUMAN
NC score	0.004551 (rank : 90)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	86	Target Neighborhood Hits	1092	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

NBEA_MOUSE
NC score	0.004132 (rank : 91)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	86	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

CAR15_HUMAN
NC score	0.003687 (rank : 92)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	86	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

TRHY_HUMAN
NC score	0.003500 (rank : 93)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	86	Target Neighborhood Hits	1385	Shared Neighborhood Hits	19
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

ZN292_HUMAN
NC score	0.002070 (rank : 94)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	86	Target Neighborhood Hits	918	Shared Neighborhood Hits	3
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

CING_MOUSE
NC score	0.001941 (rank : 95)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	86	Target Neighborhood Hits	1432	Shared Neighborhood Hits	20
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.