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Network neighborhood for query Sequence : GAB2_MOUSE

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GAB2_MOUSE
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GAB2_HUMAN
θ value	0 (rank : 1)	NC score	0.968699 (rank : 2)
Query Neighborhood Hits	220	Target Neighborhood Hits	188	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GAB2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	220	Target Neighborhood Hits	220	Shared Neighborhood Hits	220
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

GAB1_HUMAN
θ value	2.70778e-113 (rank : 3)	NC score	0.866376 (rank : 4)
Query Neighborhood Hits	220	Target Neighborhood Hits	279	Shared Neighborhood Hits	77
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_MOUSE
θ value	2.70778e-113 (rank : 4)	NC score	0.872651 (rank : 3)
Query Neighborhood Hits	220	Target Neighborhood Hits	233	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PKHA1_MOUSE
θ value	1.99992e-07 (rank : 5)	NC score	0.402944 (rank : 5)
Query Neighborhood Hits	220	Target Neighborhood Hits	120	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

IRS1_HUMAN
θ value	7.59969e-07 (rank : 6)	NC score	0.253146 (rank : 11)
Query Neighborhood Hits	220	Target Neighborhood Hits	109	Shared Neighborhood Hits	24
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

PKHA1_HUMAN
θ value	7.59969e-07 (rank : 7)	NC score	0.390192 (rank : 6)
Query Neighborhood Hits	220	Target Neighborhood Hits	127	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_HUMAN
θ value	9.92553e-07 (rank : 8)	NC score	0.380448 (rank : 7)
Query Neighborhood Hits	220	Target Neighborhood Hits	119	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

SRRM2_MOUSE
θ value	9.92553e-07 (rank : 9)	NC score	0.156996 (rank : 30)
Query Neighborhood Hits	220	Target Neighborhood Hits	1470	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

DOC10_HUMAN
θ value	1.69304e-06 (rank : 10)	NC score	0.141770 (rank : 37)
Query Neighborhood Hits	220	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

MYO10_HUMAN
θ value	1.69304e-06 (rank : 11)	NC score	0.120194 (rank : 49)
Query Neighborhood Hits	220	Target Neighborhood Hits	920	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

IRS1_MOUSE
θ value	2.21117e-06 (rank : 12)	NC score	0.244278 (rank : 16)
Query Neighborhood Hits	220	Target Neighborhood Hits	112	Shared Neighborhood Hits	23
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

PKHA2_MOUSE
θ value	4.92598e-06 (rank : 13)	NC score	0.376728 (rank : 8)
Query Neighborhood Hits	220	Target Neighborhood Hits	116	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

CNKR2_HUMAN
θ value	1.43324e-05 (rank : 14)	NC score	0.247737 (rank : 14)
Query Neighborhood Hits	220	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	1.43324e-05 (rank : 15)	NC score	0.247861 (rank : 13)
Query Neighborhood Hits	220	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PLEK_MOUSE
θ value	7.1131e-05 (rank : 16)	NC score	0.314576 (rank : 10)
Query Neighborhood Hits	220	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

DAPP1_MOUSE
θ value	9.29e-05 (rank : 17)	NC score	0.247983 (rank : 12)
Query Neighborhood Hits	220	Target Neighborhood Hits	225	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PLEK_HUMAN
θ value	9.29e-05 (rank : 18)	NC score	0.319716 (rank : 9)
Query Neighborhood Hits	220	Target Neighborhood Hits	110	Shared Neighborhood Hits	48
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

DAPP1_HUMAN
θ value	0.000121331 (rank : 19)	NC score	0.244912 (rank : 15)
Query Neighborhood Hits	220	Target Neighborhood Hits	227	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PHLB1_MOUSE
θ value	0.000121331 (rank : 20)	NC score	0.224793 (rank : 17)
Query Neighborhood Hits	220	Target Neighborhood Hits	678	Shared Neighborhood Hits	72
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CEND2_HUMAN
θ value	0.000270298 (rank : 21)	NC score	0.136022 (rank : 41)
Query Neighborhood Hits	220	Target Neighborhood Hits	166	Shared Neighborhood Hits	38
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

PHLB2_MOUSE
θ value	0.000270298 (rank : 22)	NC score	0.172961 (rank : 26)
Query Neighborhood Hits	220	Target Neighborhood Hits	1016	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_HUMAN
θ value	0.00035302 (rank : 23)	NC score	0.177416 (rank : 24)
Query Neighborhood Hits	220	Target Neighborhood Hits	964	Shared Neighborhood Hits	58
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

MRIP_HUMAN
θ value	0.000461057 (rank : 24)	NC score	0.171316 (rank : 27)
Query Neighborhood Hits	220	Target Neighborhood Hits	578	Shared Neighborhood Hits	55
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

RHG25_HUMAN
θ value	0.000602161 (rank : 25)	NC score	0.138359 (rank : 39)
Query Neighborhood Hits	220	Target Neighborhood Hits	550	Shared Neighborhood Hits	58
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SRRM2_HUMAN
θ value	0.00102713 (rank : 26)	NC score	0.158963 (rank : 29)
Query Neighborhood Hits	220	Target Neighborhood Hits	1296	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MRIP_MOUSE
θ value	0.00134147 (rank : 27)	NC score	0.162815 (rank : 28)
Query Neighborhood Hits	220	Target Neighborhood Hits	569	Shared Neighborhood Hits	54
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

RASA2_MOUSE
θ value	0.00175202 (rank : 28)	NC score	0.131000 (rank : 45)
Query Neighborhood Hits	220	Target Neighborhood Hits	159	Shared Neighborhood Hits	30
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

PHLB1_HUMAN
θ value	0.00228821 (rank : 29)	NC score	0.197775 (rank : 21)
Query Neighborhood Hits	220	Target Neighborhood Hits	1038	Shared Neighborhood Hits	88
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

OSBP1_HUMAN
θ value	0.00390308 (rank : 30)	NC score	0.109431 (rank : 56)
Query Neighborhood Hits	220	Target Neighborhood Hits	180	Shared Neighborhood Hits	44
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

CEND1_HUMAN
θ value	0.00509761 (rank : 31)	NC score	0.139509 (rank : 38)
Query Neighborhood Hits	220	Target Neighborhood Hits	284	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

ZIM10_MOUSE
θ value	0.00665767 (rank : 32)	NC score	0.072534 (rank : 85)
Query Neighborhood Hits	220	Target Neighborhood Hits	430	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CS007_MOUSE
θ value	0.0113563 (rank : 33)	NC score	0.076196 (rank : 77)
Query Neighborhood Hits	220	Target Neighborhood Hits	464	Shared Neighborhood Hits	36
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

RPB1_HUMAN
θ value	0.0148317 (rank : 34)	NC score	0.127284 (rank : 48)
Query Neighborhood Hits	220	Target Neighborhood Hits	362	Shared Neighborhood Hits	35
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.0148317 (rank : 35)	NC score	0.127524 (rank : 47)
Query Neighborhood Hits	220	Target Neighborhood Hits	363	Shared Neighborhood Hits	36
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

SHAN1_HUMAN
θ value	0.0148317 (rank : 36)	NC score	0.049728 (rank : 138)
Query Neighborhood Hits	220	Target Neighborhood Hits	1041	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SWP70_HUMAN
θ value	0.0148317 (rank : 37)	NC score	0.132875 (rank : 44)
Query Neighborhood Hits	220	Target Neighborhood Hits	973	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

FILA_HUMAN
θ value	0.0252991 (rank : 38)	NC score	0.054222 (rank : 124)
Query Neighborhood Hits	220	Target Neighborhood Hits	685	Shared Neighborhood Hits	28
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

MAGC1_HUMAN
θ value	0.0252991 (rank : 39)	NC score	0.057541 (rank : 114)
Query Neighborhood Hits	220	Target Neighborhood Hits	431	Shared Neighborhood Hits	37
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

RASA1_HUMAN
θ value	0.0252991 (rank : 40)	NC score	0.135013 (rank : 42)
Query Neighborhood Hits	220	Target Neighborhood Hits	258	Shared Neighborhood Hits	39
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

SHPS1_HUMAN
θ value	0.0252991 (rank : 41)	NC score	0.032153 (rank : 176)
Query Neighborhood Hits	220	Target Neighborhood Hits	455	Shared Neighborhood Hits	5
SwissProt Accessions	P78324, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9	Gene names	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (Sirp-alpha-2) (Sirp-alpha- 3) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusion receptor) (p84) (CD172a antigen).

SWP70_MOUSE
θ value	0.0252991 (rank : 42)	NC score	0.133349 (rank : 43)
Query Neighborhood Hits	220	Target Neighborhood Hits	1097	Shared Neighborhood Hits	65
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

ZIM10_HUMAN
θ value	0.0252991 (rank : 43)	NC score	0.072305 (rank : 86)
Query Neighborhood Hits	220	Target Neighborhood Hits	577	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CT174_HUMAN
θ value	0.0330416 (rank : 44)	NC score	0.083172 (rank : 67)
Query Neighborhood Hits	220	Target Neighborhood Hits	181	Shared Neighborhood Hits	27
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

DOCK9_MOUSE
θ value	0.0330416 (rank : 45)	NC score	0.115411 (rank : 52)
Query Neighborhood Hits	220	Target Neighborhood Hits	79	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

RASA2_HUMAN
θ value	0.0330416 (rank : 46)	NC score	0.110295 (rank : 54)
Query Neighborhood Hits	220	Target Neighborhood Hits	157	Shared Neighborhood Hits	26
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

ZN335_HUMAN
θ value	0.0330416 (rank : 47)	NC score	0.006408 (rank : 248)
Query Neighborhood Hits	220	Target Neighborhood Hits	973	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

MTMR5_HUMAN
θ value	0.0563607 (rank : 48)	NC score	0.116872 (rank : 50)
Query Neighborhood Hits	220	Target Neighborhood Hits	141	Shared Neighborhood Hits	37
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

CNKR1_HUMAN
θ value	0.0736092 (rank : 49)	NC score	0.223519 (rank : 18)
Query Neighborhood Hits	220	Target Neighborhood Hits	154	Shared Neighborhood Hits	44
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

SC24D_HUMAN
θ value	0.0736092 (rank : 50)	NC score	0.052927 (rank : 128)
Query Neighborhood Hits	220	Target Neighborhood Hits	173	Shared Neighborhood Hits	15
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

PEX5R_HUMAN
θ value	0.0961366 (rank : 51)	NC score	0.059290 (rank : 110)
Query Neighborhood Hits	220	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IYB4, Q9NQD1, Q9P2U3, Q9P2U4	Gene names	PEX5L, PEX5R, PXR2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

ROBO1_HUMAN
θ value	0.0961366 (rank : 52)	NC score	0.014895 (rank : 224)
Query Neighborhood Hits	220	Target Neighborhood Hits	529	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

RUNX2_HUMAN
θ value	0.0961366 (rank : 53)	NC score	0.053309 (rank : 126)
Query Neighborhood Hits	220	Target Neighborhood Hits	103	Shared Neighborhood Hits	15
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

TARA_MOUSE
θ value	0.0961366 (rank : 54)	NC score	0.149883 (rank : 32)
Query Neighborhood Hits	220	Target Neighborhood Hits	1133	Shared Neighborhood Hits	85
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TBCD2_HUMAN
θ value	0.0961366 (rank : 55)	NC score	0.113245 (rank : 53)
Query Neighborhood Hits	220	Target Neighborhood Hits	419	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

CEND1_MOUSE
θ value	0.125558 (rank : 56)	NC score	0.110243 (rank : 55)
Query Neighborhood Hits	220	Target Neighborhood Hits	260	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

OSBP2_MOUSE
θ value	0.125558 (rank : 57)	NC score	0.105862 (rank : 58)
Query Neighborhood Hits	220	Target Neighborhood Hits	150	Shared Neighborhood Hits	46
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

AF17_HUMAN
θ value	0.163984 (rank : 58)	NC score	0.044414 (rank : 149)
Query Neighborhood Hits	220	Target Neighborhood Hits	230	Shared Neighborhood Hits	20
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

EMSY_MOUSE
θ value	0.163984 (rank : 59)	NC score	0.040239 (rank : 156)
Query Neighborhood Hits	220	Target Neighborhood Hits	294	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

MTMRD_HUMAN
θ value	0.163984 (rank : 60)	NC score	0.107207 (rank : 57)
Query Neighborhood Hits	220	Target Neighborhood Hits	135	Shared Neighborhood Hits	42
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

PKHA5_HUMAN
θ value	0.163984 (rank : 61)	NC score	0.180697 (rank : 22)
Query Neighborhood Hits	220	Target Neighborhood Hits	455	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

SGIP1_MOUSE
θ value	0.163984 (rank : 62)	NC score	0.081780 (rank : 69)
Query Neighborhood Hits	220	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

MAST3_HUMAN
θ value	0.21417 (rank : 63)	NC score	0.011046 (rank : 238)
Query Neighborhood Hits	220	Target Neighborhood Hits	1128	Shared Neighborhood Hits	38
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

NOLC1_HUMAN
θ value	0.21417 (rank : 64)	NC score	0.061294 (rank : 106)
Query Neighborhood Hits	220	Target Neighborhood Hits	452	Shared Neighborhood Hits	24
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

AF10_HUMAN
θ value	0.279714 (rank : 65)	NC score	0.033882 (rank : 172)
Query Neighborhood Hits	220	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

BCL9_MOUSE
θ value	0.279714 (rank : 66)	NC score	0.063345 (rank : 103)
Query Neighborhood Hits	220	Target Neighborhood Hits	770	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CIC_MOUSE
θ value	0.279714 (rank : 67)	NC score	0.042262 (rank : 152)
Query Neighborhood Hits	220	Target Neighborhood Hits	742	Shared Neighborhood Hits	64
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ENAH_MOUSE
θ value	0.279714 (rank : 68)	NC score	0.059265 (rank : 111)
Query Neighborhood Hits	220	Target Neighborhood Hits	919	Shared Neighborhood Hits	52
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PLEK2_HUMAN
θ value	0.279714 (rank : 69)	NC score	0.206430 (rank : 19)
Query Neighborhood Hits	220	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	0.279714 (rank : 70)	NC score	0.206325 (rank : 20)
Query Neighborhood Hits	220	Target Neighborhood Hits	96	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PYGO1_HUMAN
θ value	0.279714 (rank : 71)	NC score	0.078993 (rank : 72)
Query Neighborhood Hits	220	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

RUNX2_MOUSE
θ value	0.279714 (rank : 72)	NC score	0.049696 (rank : 139)
Query Neighborhood Hits	220	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

WNK4_HUMAN
θ value	0.279714 (rank : 73)	NC score	0.018683 (rank : 208)
Query Neighborhood Hits	220	Target Neighborhood Hits	1043	Shared Neighborhood Hits	35
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

UBP29_HUMAN
θ value	0.365318 (rank : 74)	NC score	0.032449 (rank : 175)
Query Neighborhood Hits	220	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

C43BP_MOUSE
θ value	0.47712 (rank : 75)	NC score	0.149633 (rank : 33)
Query Neighborhood Hits	220	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CD2L5_HUMAN
θ value	0.47712 (rank : 76)	NC score	0.010935 (rank : 239)
Query Neighborhood Hits	220	Target Neighborhood Hits	987	Shared Neighborhood Hits	30
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

K0460_HUMAN
θ value	0.47712 (rank : 77)	NC score	0.056274 (rank : 116)
Query Neighborhood Hits	220	Target Neighborhood Hits	357	Shared Neighborhood Hits	29
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

MUC15_MOUSE
θ value	0.47712 (rank : 78)	NC score	0.071798 (rank : 88)
Query Neighborhood Hits	220	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C6Z1, Q3UQC4, Q6XYQ9, Q7TMH6, Q8CE82	Gene names	Muc15
Domain Architecture	No domain graphic available
Description	Mucin-15 precursor.

NACAM_MOUSE
θ value	0.47712 (rank : 79)	NC score	0.084962 (rank : 64)
Query Neighborhood Hits	220	Target Neighborhood Hits	1866	Shared Neighborhood Hits	111
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

OSBP2_HUMAN
θ value	0.47712 (rank : 80)	NC score	0.097851 (rank : 60)
Query Neighborhood Hits	220	Target Neighborhood Hits	154	Shared Neighborhood Hits	46
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

REPS2_MOUSE
θ value	0.47712 (rank : 81)	NC score	0.029752 (rank : 178)
Query Neighborhood Hits	220	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

TACC2_MOUSE
θ value	0.47712 (rank : 82)	NC score	0.046161 (rank : 146)
Query Neighborhood Hits	220	Target Neighborhood Hits	774	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TARA_HUMAN
θ value	0.47712 (rank : 83)	NC score	0.138079 (rank : 40)
Query Neighborhood Hits	220	Target Neighborhood Hits	1626	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

BCL9_HUMAN
θ value	0.62314 (rank : 84)	NC score	0.070337 (rank : 90)
Query Neighborhood Hits	220	Target Neighborhood Hits	1008	Shared Neighborhood Hits	74
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

IRS2_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.142731 (rank : 36)
Query Neighborhood Hits	220	Target Neighborhood Hits	262	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

K0586_HUMAN
θ value	0.62314 (rank : 86)	NC score	0.039406 (rank : 158)
Query Neighborhood Hits	220	Target Neighborhood Hits	311	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

MAST4_HUMAN
θ value	0.62314 (rank : 87)	NC score	0.019086 (rank : 207)
Query Neighborhood Hits	220	Target Neighborhood Hits	1804	Shared Neighborhood Hits	83
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PDLI5_MOUSE
θ value	0.62314 (rank : 88)	NC score	0.024938 (rank : 191)
Query Neighborhood Hits	220	Target Neighborhood Hits	287	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

RASL1_MOUSE
θ value	0.62314 (rank : 89)	NC score	0.056167 (rank : 117)
Query Neighborhood Hits	220	Target Neighborhood Hits	148	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

WASIP_MOUSE
θ value	0.62314 (rank : 90)	NC score	0.086085 (rank : 63)
Query Neighborhood Hits	220	Target Neighborhood Hits	392	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

C43BP_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.130036 (rank : 46)
Query Neighborhood Hits	220	Target Neighborhood Hits	87	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CD2L5_MOUSE
θ value	0.813845 (rank : 92)	NC score	0.011428 (rank : 235)
Query Neighborhood Hits	220	Target Neighborhood Hits	1011	Shared Neighborhood Hits	31
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

IRS2_MOUSE
θ value	0.813845 (rank : 93)	NC score	0.149144 (rank : 34)
Query Neighborhood Hits	220	Target Neighborhood Hits	248	Shared Neighborhood Hits	37
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

PER3_HUMAN
θ value	0.813845 (rank : 94)	NC score	0.054648 (rank : 120)
Query Neighborhood Hits	220	Target Neighborhood Hits	479	Shared Neighborhood Hits	43
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

REXO1_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.049093 (rank : 140)
Query Neighborhood Hits	220	Target Neighborhood Hits	242	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

SGIP1_HUMAN
θ value	0.813845 (rank : 96)	NC score	0.076845 (rank : 76)
Query Neighborhood Hits	220	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

CUBN_MOUSE
θ value	1.06291 (rank : 97)	NC score	0.004629 (rank : 254)
Query Neighborhood Hits	220	Target Neighborhood Hits	477	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

GPTC8_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.050098 (rank : 137)
Query Neighborhood Hits	220	Target Neighborhood Hits	366	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

MUC2_HUMAN
θ value	1.06291 (rank : 99)	NC score	0.043581 (rank : 150)
Query Neighborhood Hits	220	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

OSBL6_HUMAN
θ value	1.06291 (rank : 100)	NC score	0.059873 (rank : 109)
Query Neighborhood Hits	220	Target Neighborhood Hits	101	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_MOUSE
θ value	1.06291 (rank : 101)	NC score	0.060235 (rank : 107)
Query Neighborhood Hits	220	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

ROBO1_MOUSE
θ value	1.06291 (rank : 102)	NC score	0.012678 (rank : 231)
Query Neighborhood Hits	220	Target Neighborhood Hits	559	Shared Neighborhood Hits	12
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

SET1A_HUMAN
θ value	1.06291 (rank : 103)	NC score	0.040055 (rank : 157)
Query Neighborhood Hits	220	Target Neighborhood Hits	690	Shared Neighborhood Hits	36
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SF3A1_HUMAN
θ value	1.06291 (rank : 104)	NC score	0.039042 (rank : 160)
Query Neighborhood Hits	220	Target Neighborhood Hits	199	Shared Neighborhood Hits	18
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SOX15_HUMAN
θ value	1.06291 (rank : 105)	NC score	0.016409 (rank : 220)
Query Neighborhood Hits	220	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SYNJ1_HUMAN
θ value	1.06291 (rank : 106)	NC score	0.040809 (rank : 154)
Query Neighborhood Hits	220	Target Neighborhood Hits	498	Shared Neighborhood Hits	38
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

WIRE_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.065762 (rank : 100)
Query Neighborhood Hits	220	Target Neighborhood Hits	329	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

AFF1_HUMAN
θ value	1.38821 (rank : 108)	NC score	0.056059 (rank : 118)
Query Neighborhood Hits	220	Target Neighborhood Hits	506	Shared Neighborhood Hits	35
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

DOK2_MOUSE
θ value	1.38821 (rank : 109)	NC score	0.047141 (rank : 144)
Query Neighborhood Hits	220	Target Neighborhood Hits	244	Shared Neighborhood Hits	29
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

GCX1_HUMAN
θ value	1.38821 (rank : 110)	NC score	0.028593 (rank : 181)
Query Neighborhood Hits	220	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

GFRA2_HUMAN
θ value	1.38821 (rank : 111)	NC score	0.024917 (rank : 192)
Query Neighborhood Hits	220	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

OSB11_MOUSE
θ value	1.38821 (rank : 112)	NC score	0.058917 (rank : 112)
Query Neighborhood Hits	220	Target Neighborhood Hits	71	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

PKHA4_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.146778 (rank : 35)
Query Neighborhood Hits	220	Target Neighborhood Hits	283	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	1.38821 (rank : 114)	NC score	0.152442 (rank : 31)
Query Neighborhood Hits	220	Target Neighborhood Hits	202	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA6_HUMAN
θ value	1.38821 (rank : 115)	NC score	0.173162 (rank : 25)
Query Neighborhood Hits	220	Target Neighborhood Hits	556	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SETBP_MOUSE
θ value	1.38821 (rank : 116)	NC score	0.066155 (rank : 98)
Query Neighborhood Hits	220	Target Neighborhood Hits	352	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SP4_MOUSE
θ value	1.38821 (rank : 117)	NC score	0.004954 (rank : 252)
Query Neighborhood Hits	220	Target Neighborhood Hits	759	Shared Neighborhood Hits	11
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

TTC16_HUMAN
θ value	1.38821 (rank : 118)	NC score	0.045393 (rank : 147)
Query Neighborhood Hits	220	Target Neighborhood Hits	417	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

WNK4_MOUSE
θ value	1.38821 (rank : 119)	NC score	0.014869 (rank : 225)
Query Neighborhood Hits	220	Target Neighborhood Hits	961	Shared Neighborhood Hits	31
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZDHC8_HUMAN
θ value	1.38821 (rank : 120)	NC score	0.041221 (rank : 153)
Query Neighborhood Hits	220	Target Neighborhood Hits	234	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

ABL1_HUMAN
θ value	1.81305 (rank : 121)	NC score	0.008320 (rank : 242)
Query Neighborhood Hits	220	Target Neighborhood Hits	1220	Shared Neighborhood Hits	37
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ARI1A_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.048509 (rank : 141)
Query Neighborhood Hits	220	Target Neighborhood Hits	787	Shared Neighborhood Hits	56
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

AUTS2_HUMAN
θ value	1.81305 (rank : 123)	NC score	0.047333 (rank : 142)
Query Neighborhood Hits	220	Target Neighborhood Hits	342	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

KIF1A_MOUSE
θ value	1.81305 (rank : 124)	NC score	0.021544 (rank : 203)
Query Neighborhood Hits	220	Target Neighborhood Hits	239	Shared Neighborhood Hits	18
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

KIFC3_HUMAN
θ value	1.81305 (rank : 125)	NC score	0.017228 (rank : 212)
Query Neighborhood Hits	220	Target Neighborhood Hits	619	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

PKHA6_MOUSE
θ value	1.81305 (rank : 126)	NC score	0.180215 (rank : 23)
Query Neighborhood Hits	220	Target Neighborhood Hits	591	Shared Neighborhood Hits	81
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RAPH1_HUMAN
θ value	1.81305 (rank : 127)	NC score	0.080721 (rank : 70)
Query Neighborhood Hits	220	Target Neighborhood Hits	593	Shared Neighborhood Hits	52
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SYNP2_HUMAN
θ value	1.81305 (rank : 128)	NC score	0.042689 (rank : 151)
Query Neighborhood Hits	220	Target Neighborhood Hits	323	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TENS1_HUMAN
θ value	1.81305 (rank : 129)	NC score	0.047286 (rank : 143)
Query Neighborhood Hits	220	Target Neighborhood Hits	400	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

VDR_MOUSE
θ value	1.81305 (rank : 130)	NC score	0.006805 (rank : 246)
Query Neighborhood Hits	220	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

ZO1_MOUSE
θ value	1.81305 (rank : 131)	NC score	0.026866 (rank : 184)
Query Neighborhood Hits	220	Target Neighborhood Hits	453	Shared Neighborhood Hits	34
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

AFF1_MOUSE
θ value	2.36792 (rank : 132)	NC score	0.037988 (rank : 163)
Query Neighborhood Hits	220	Target Neighborhood Hits	351	Shared Neighborhood Hits	18
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

BRDT_HUMAN
θ value	2.36792 (rank : 133)	NC score	0.018664 (rank : 209)
Query Neighborhood Hits	220	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

CENB2_HUMAN
θ value	2.36792 (rank : 134)	NC score	0.077515 (rank : 74)
Query Neighborhood Hits	220	Target Neighborhood Hits	425	Shared Neighborhood Hits	46
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

DOK2_HUMAN
θ value	2.36792 (rank : 135)	NC score	0.033238 (rank : 174)
Query Neighborhood Hits	220	Target Neighborhood Hits	46	Shared Neighborhood Hits	7
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

EGFR_HUMAN
θ value	2.36792 (rank : 136)	NC score	0.006674 (rank : 247)
Query Neighborhood Hits	220	Target Neighborhood Hits	939	Shared Neighborhood Hits	18
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

LDB3_MOUSE
θ value	2.36792 (rank : 137)	NC score	0.027518 (rank : 183)
Query Neighborhood Hits	220	Target Neighborhood Hits	510	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MINT_HUMAN
θ value	2.36792 (rank : 138)	NC score	0.036567 (rank : 167)
Query Neighborhood Hits	220	Target Neighborhood Hits	1291	Shared Neighborhood Hits	61
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PDE3A_MOUSE
θ value	2.36792 (rank : 139)	NC score	0.021980 (rank : 201)
Query Neighborhood Hits	220	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PRR12_HUMAN
θ value	2.36792 (rank : 140)	NC score	0.046394 (rank : 145)
Query Neighborhood Hits	220	Target Neighborhood Hits	460	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SYNP2_MOUSE
θ value	2.36792 (rank : 141)	NC score	0.034454 (rank : 171)
Query Neighborhood Hits	220	Target Neighborhood Hits	252	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

ZDHC5_HUMAN
θ value	2.36792 (rank : 142)	NC score	0.025410 (rank : 189)
Query Neighborhood Hits	220	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0B5, Q6ZMF0, Q8TAK8, Q9H923, Q9UFI7	Gene names	ZDHHC5, KIAA1748, ZNF375
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375).

BSN_HUMAN
θ value	3.0926 (rank : 143)	NC score	0.062175 (rank : 105)
Query Neighborhood Hits	220	Target Neighborhood Hits	1537	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

ENAH_HUMAN
θ value	3.0926 (rank : 144)	NC score	0.044923 (rank : 148)
Query Neighborhood Hits	220	Target Neighborhood Hits	784	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

GFRA2_MOUSE
θ value	3.0926 (rank : 145)	NC score	0.022294 (rank : 200)
Query Neighborhood Hits	220	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

ICB1_MOUSE
θ value	3.0926 (rank : 146)	NC score	0.020293 (rank : 206)
Query Neighborhood Hits	220	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

IP3KC_MOUSE
θ value	3.0926 (rank : 147)	NC score	0.016084 (rank : 221)
Query Neighborhood Hits	220	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TS72, Q3U384	Gene names	Itpkc
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (IP3K-C).

PCLO_HUMAN
θ value	3.0926 (rank : 148)	NC score	0.056932 (rank : 115)
Query Neighborhood Hits	220	Target Neighborhood Hits	2046	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SDC1_HUMAN
θ value	3.0926 (rank : 149)	NC score	0.025120 (rank : 190)
Query Neighborhood Hits	220	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	P18827, Q96HB7	Gene names	SDC1, SDC
Domain Architecture
Description	Syndecan-1 precursor (SYND1) (CD138 antigen).

SETBP_HUMAN
θ value	3.0926 (rank : 150)	NC score	0.053812 (rank : 125)
Query Neighborhood Hits	220	Target Neighborhood Hits	305	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

ZDHC5_MOUSE
θ value	3.0926 (rank : 151)	NC score	0.026425 (rank : 185)
Query Neighborhood Hits	220	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VDZ4, Q69ZB5, Q8R2X7	Gene names	Zdhhc5, Kiaa1748
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5).

ZDHC8_MOUSE
θ value	3.0926 (rank : 152)	NC score	0.040589 (rank : 155)
Query Neighborhood Hits	220	Target Neighborhood Hits	243	Shared Neighborhood Hits	25
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

AFF4_MOUSE
θ value	4.03905 (rank : 153)	NC score	0.037843 (rank : 164)
Query Neighborhood Hits	220	Target Neighborhood Hits	581	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

CABL2_MOUSE
θ value	4.03905 (rank : 154)	NC score	0.014628 (rank : 227)
Query Neighborhood Hits	220	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

CASC5_MOUSE
θ value	4.03905 (rank : 155)	NC score	0.029969 (rank : 177)
Query Neighborhood Hits	220	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

CENB5_HUMAN
θ value	4.03905 (rank : 156)	NC score	0.074232 (rank : 82)
Query Neighborhood Hits	220	Target Neighborhood Hits	395	Shared Neighborhood Hits	47
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

FA53C_MOUSE
θ value	4.03905 (rank : 157)	NC score	0.018141 (rank : 211)
Query Neighborhood Hits	220	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BXQ8, Q3U4J2	Gene names	Fam53c
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

HCN4_MOUSE
θ value	4.03905 (rank : 158)	NC score	0.015791 (rank : 222)
Query Neighborhood Hits	220	Target Neighborhood Hits	284	Shared Neighborhood Hits	18
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HXD9_HUMAN
θ value	4.03905 (rank : 159)	NC score	0.002149 (rank : 257)
Query Neighborhood Hits	220	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	P28356	Gene names	HOXD9, HOX4C
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2).

MACF1_MOUSE
θ value	4.03905 (rank : 160)	NC score	0.012487 (rank : 232)
Query Neighborhood Hits	220	Target Neighborhood Hits	1313	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

RIMB2_HUMAN
θ value	4.03905 (rank : 161)	NC score	0.015285 (rank : 223)
Query Neighborhood Hits	220	Target Neighborhood Hits	263	Shared Neighborhood Hits	9
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SCMH1_MOUSE
θ value	4.03905 (rank : 162)	NC score	0.013346 (rank : 229)
Query Neighborhood Hits	220	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K214, Q9JME0	Gene names	Scmh1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

SF3A1_MOUSE
θ value	4.03905 (rank : 163)	NC score	0.035930 (rank : 169)
Query Neighborhood Hits	220	Target Neighborhood Hits	198	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SP4_HUMAN
θ value	4.03905 (rank : 164)	NC score	0.002949 (rank : 256)
Query Neighborhood Hits	220	Target Neighborhood Hits	749	Shared Neighborhood Hits	9
SwissProt Accessions	Q02446, O60402	Gene names	SP4
Domain Architecture
Description	Transcription factor Sp4 (SPR-1).

SPT6H_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.023767 (rank : 196)
Query Neighborhood Hits	220	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

SPT6H_MOUSE
θ value	4.03905 (rank : 166)	NC score	0.024321 (rank : 194)
Query Neighborhood Hits	220	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

SRRM1_MOUSE
θ value	4.03905 (rank : 167)	NC score	0.090887 (rank : 61)
Query Neighborhood Hits	220	Target Neighborhood Hits	966	Shared Neighborhood Hits	73
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ATF7_MOUSE
θ value	5.27518 (rank : 168)	NC score	0.013024 (rank : 230)
Query Neighborhood Hits	220	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

BAZ2B_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.023698 (rank : 197)
Query Neighborhood Hits	220	Target Neighborhood Hits	803	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CD2AP_MOUSE
θ value	5.27518 (rank : 170)	NC score	0.013650 (rank : 228)
Query Neighborhood Hits	220	Target Neighborhood Hits	336	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CD2L7_HUMAN
θ value	5.27518 (rank : 171)	NC score	0.011540 (rank : 234)
Query Neighborhood Hits	220	Target Neighborhood Hits	1275	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

DCP1A_MOUSE
θ value	5.27518 (rank : 172)	NC score	0.036520 (rank : 168)
Query Neighborhood Hits	220	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

FARP1_HUMAN
θ value	5.27518 (rank : 173)	NC score	0.033387 (rank : 173)
Query Neighborhood Hits	220	Target Neighborhood Hits	241	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FLNB_HUMAN
θ value	5.27518 (rank : 174)	NC score	0.007368 (rank : 244)
Query Neighborhood Hits	220	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

GNAS1_MOUSE
θ value	5.27518 (rank : 175)	NC score	0.020528 (rank : 205)
Query Neighborhood Hits	220	Target Neighborhood Hits	651	Shared Neighborhood Hits	45
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

K0310_HUMAN
θ value	5.27518 (rank : 176)	NC score	0.039153 (rank : 159)
Query Neighborhood Hits	220	Target Neighborhood Hits	420	Shared Neighborhood Hits	43
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

KPCD1_HUMAN
θ value	5.27518 (rank : 177)	NC score	0.006254 (rank : 250)
Query Neighborhood Hits	220	Target Neighborhood Hits	901	Shared Neighborhood Hits	17
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

LDB3_HUMAN
θ value	5.27518 (rank : 178)	NC score	0.024730 (rank : 193)
Query Neighborhood Hits	220	Target Neighborhood Hits	497	Shared Neighborhood Hits	33
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

MINK1_MOUSE
θ value	5.27518 (rank : 179)	NC score	0.005531 (rank : 251)
Query Neighborhood Hits	220	Target Neighborhood Hits	1451	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

RAI14_MOUSE
θ value	5.27518 (rank : 180)	NC score	0.016750 (rank : 215)
Query Neighborhood Hits	220	Target Neighborhood Hits	1505	Shared Neighborhood Hits	53
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

T240L_MOUSE
θ value	5.27518 (rank : 181)	NC score	0.025965 (rank : 186)
Query Neighborhood Hits	220	Target Neighborhood Hits	143	Shared Neighborhood Hits	11
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

ZN408_HUMAN
θ value	5.27518 (rank : 182)	NC score	-0.002980 (rank : 258)
Query Neighborhood Hits	220	Target Neighborhood Hits	775	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).

AF9_HUMAN
θ value	6.88961 (rank : 183)	NC score	0.038888 (rank : 161)
Query Neighborhood Hits	220	Target Neighborhood Hits	202	Shared Neighborhood Hits	18
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

CEND3_HUMAN
θ value	6.88961 (rank : 184)	NC score	0.072201 (rank : 87)
Query Neighborhood Hits	220	Target Neighborhood Hits	275	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CHD1_MOUSE
θ value	6.88961 (rank : 185)	NC score	0.004547 (rank : 255)
Query Neighborhood Hits	220	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CSKI2_MOUSE
θ value	6.88961 (rank : 186)	NC score	0.016583 (rank : 217)
Query Neighborhood Hits	220	Target Neighborhood Hits	812	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DDFL1_HUMAN
θ value	6.88961 (rank : 187)	NC score	0.037011 (rank : 165)
Query Neighborhood Hits	220	Target Neighborhood Hits	353	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

EFCB3_MOUSE
θ value	6.88961 (rank : 188)	NC score	0.012234 (rank : 233)
Query Neighborhood Hits	220	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q80X60	Gene names	Efcab3
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 3.

GA2L1_HUMAN
θ value	6.88961 (rank : 189)	NC score	0.016449 (rank : 219)
Query Neighborhood Hits	220	Target Neighborhood Hits	177	Shared Neighborhood Hits	15
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

HRX_HUMAN
θ value	6.88961 (rank : 190)	NC score	0.029090 (rank : 179)
Query Neighborhood Hits	220	Target Neighborhood Hits	825	Shared Neighborhood Hits	49
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

KIF1A_HUMAN
θ value	6.88961 (rank : 191)	NC score	0.016643 (rank : 216)
Query Neighborhood Hits	220	Target Neighborhood Hits	240	Shared Neighborhood Hits	17
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

MAP4_MOUSE
θ value	6.88961 (rank : 192)	NC score	0.028835 (rank : 180)
Query Neighborhood Hits	220	Target Neighborhood Hits	409	Shared Neighborhood Hits	34
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MYO15_HUMAN
θ value	6.88961 (rank : 193)	NC score	0.023443 (rank : 198)
Query Neighborhood Hits	220	Target Neighborhood Hits	671	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PER1_MOUSE
θ value	6.88961 (rank : 194)	NC score	0.018284 (rank : 210)
Query Neighborhood Hits	220	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PI5PA_HUMAN
θ value	6.88961 (rank : 195)	NC score	0.038590 (rank : 162)
Query Neighborhood Hits	220	Target Neighborhood Hits	749	Shared Neighborhood Hits	60
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PKHA3_HUMAN
θ value	6.88961 (rank : 196)	NC score	0.088908 (rank : 62)
Query Neighborhood Hits	220	Target Neighborhood Hits	66	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

RNAS7_HUMAN
θ value	6.88961 (rank : 197)	NC score	0.008516 (rank : 241)
Query Neighborhood Hits	220	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H1E1, P80927, P83685	Gene names	RNASE7
Domain Architecture
Description	Ribonuclease 7 precursor (EC 3.1.27.-) (RNase 7) (Skin-derived antimicrobial protein 2) (SAP-2).

SFPQ_MOUSE
θ value	6.88961 (rank : 198)	NC score	0.025617 (rank : 188)
Query Neighborhood Hits	220	Target Neighborhood Hits	958	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

TENS4_MOUSE
θ value	6.88961 (rank : 199)	NC score	0.025647 (rank : 187)
Query Neighborhood Hits	220	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

WASIP_HUMAN
θ value	6.88961 (rank : 200)	NC score	0.068914 (rank : 92)
Query Neighborhood Hits	220	Target Neighborhood Hits	458	Shared Neighborhood Hits	37
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

AP180_MOUSE
θ value	8.99809 (rank : 201)	NC score	0.021674 (rank : 202)
Query Neighborhood Hits	220	Target Neighborhood Hits	194	Shared Neighborhood Hits	13
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

ASSY_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.011068 (rank : 237)
Query Neighborhood Hits	220	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	P16460	Gene names	Ass1, Ass
Domain Architecture
Description	Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase).

BLNK_HUMAN
θ value	8.99809 (rank : 203)	NC score	0.036921 (rank : 166)
Query Neighborhood Hits	220	Target Neighborhood Hits	228	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

BRDT_MOUSE
θ value	8.99809 (rank : 204)	NC score	0.021116 (rank : 204)
Query Neighborhood Hits	220	Target Neighborhood Hits	243	Shared Neighborhood Hits	15
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CAP1_MOUSE
θ value	8.99809 (rank : 205)	NC score	0.008836 (rank : 240)
Query Neighborhood Hits	220	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P40124	Gene names	Cap1, Cap
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

CCDC4_HUMAN
θ value	8.99809 (rank : 206)	NC score	0.027711 (rank : 182)
Query Neighborhood Hits	220	Target Neighborhood Hits	104	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

CEND3_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.068562 (rank : 93)
Query Neighborhood Hits	220	Target Neighborhood Hits	228	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CROCC_HUMAN
θ value	8.99809 (rank : 208)	NC score	0.017118 (rank : 213)
Query Neighborhood Hits	220	Target Neighborhood Hits	1409	Shared Neighborhood Hits	40
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

EGFR_MOUSE
θ value	8.99809 (rank : 209)	NC score	0.004630 (rank : 253)
Query Neighborhood Hits	220	Target Neighborhood Hits	927	Shared Neighborhood Hits	18
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

GGA3_MOUSE
θ value	8.99809 (rank : 210)	NC score	0.011293 (rank : 236)
Query Neighborhood Hits	220	Target Neighborhood Hits	148	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

HN1_HUMAN
θ value	8.99809 (rank : 211)	NC score	0.023862 (rank : 195)
Query Neighborhood Hits	220	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK76, Q53FG7, Q7Z2D2, Q7Z2F0	Gene names	HN1, ARM2
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1 protein (Androgen-regulated protein 2).

JIP3_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.035027 (rank : 170)
Query Neighborhood Hits	220	Target Neighborhood Hits	1039	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

NR1D1_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.007052 (rank : 245)
Query Neighborhood Hits	220	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

RAD18_HUMAN
θ value	8.99809 (rank : 214)	NC score	0.014741 (rank : 226)
Query Neighborhood Hits	220	Target Neighborhood Hits	284	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

ROCK1_HUMAN
θ value	8.99809 (rank : 215)	NC score	0.006342 (rank : 249)
Query Neighborhood Hits	220	Target Neighborhood Hits	2000	Shared Neighborhood Hits	42
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SPIB_MOUSE
θ value	8.99809 (rank : 216)	NC score	0.007666 (rank : 243)
Query Neighborhood Hits	220	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	O35906, O35907, O35909, O55199	Gene names	Spib
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-B.

SRRM1_HUMAN
θ value	8.99809 (rank : 217)	NC score	0.083523 (rank : 66)
Query Neighborhood Hits	220	Target Neighborhood Hits	690	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

T240L_HUMAN
θ value	8.99809 (rank : 218)	NC score	0.017044 (rank : 214)
Query Neighborhood Hits	220	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

UBN1_HUMAN
θ value	8.99809 (rank : 219)	NC score	0.022488 (rank : 199)
Query Neighborhood Hits	220	Target Neighborhood Hits	170	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

UBP31_HUMAN
θ value	8.99809 (rank : 220)	NC score	0.016491 (rank : 218)
Query Neighborhood Hits	220	Target Neighborhood Hits	293	Shared Neighborhood Hits	17
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

3BP2_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.062596 (rank : 104)
Query Neighborhood Hits	220	Target Neighborhood Hits	296	Shared Neighborhood Hits	44
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.054283 (rank : 123)
Query Neighborhood Hits	220	Target Neighborhood Hits	142	Shared Neighborhood Hits	23
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

BSN_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.055094 (rank : 119)
Query Neighborhood Hits	220	Target Neighborhood Hits	2057	Shared Neighborhood Hits	111
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BTBDC_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.054349 (rank : 122)
Query Neighborhood Hits	220	Target Neighborhood Hits	248	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

CENA1_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.051287 (rank : 133)
Query Neighborhood Hits	220	Target Neighborhood Hits	87	Shared Neighborhood Hits	33
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.052155 (rank : 132)
Query Neighborhood Hits	220	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENA2_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.052361 (rank : 130)
Query Neighborhood Hits	220	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.070607 (rank : 89)
Query Neighborhood Hits	220	Target Neighborhood Hits	383	Shared Neighborhood Hits	42
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CYH1_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.081994 (rank : 68)
Query Neighborhood Hits	220	Target Neighborhood Hits	184	Shared Neighborhood Hits	51
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.079488 (rank : 71)
Query Neighborhood Hits	220	Target Neighborhood Hits	176	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH2_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.074299 (rank : 80)
Query Neighborhood Hits	220	Target Neighborhood Hits	175	Shared Neighborhood Hits	49
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.074290 (rank : 81)
Query Neighborhood Hits	220	Target Neighborhood Hits	171	Shared Neighborhood Hits	49
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.069840 (rank : 91)
Query Neighborhood Hits	220	Target Neighborhood Hits	137	Shared Neighborhood Hits	45
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH3_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.076982 (rank : 75)
Query Neighborhood Hits	220	Target Neighborhood Hits	148	Shared Neighborhood Hits	48
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH4_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.074360 (rank : 79)
Query Neighborhood Hits	220	Target Neighborhood Hits	135	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH4_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.073190 (rank : 84)
Query Neighborhood Hits	220	Target Neighborhood Hits	134	Shared Neighborhood Hits	46
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

DGKH_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.057771 (rank : 113)
Query Neighborhood Hits	220	Target Neighborhood Hits	255	Shared Neighborhood Hits	43
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DOCK9_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.103828 (rank : 59)
Query Neighborhood Hits	220	Target Neighborhood Hits	82	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

LCP2_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.060067 (rank : 108)
Query Neighborhood Hits	220	Target Neighborhood Hits	531	Shared Neighborhood Hits	59
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MAGE1_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.052474 (rank : 129)
Query Neighborhood Hits	220	Target Neighborhood Hits	1389	Shared Neighborhood Hits	101
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MDC1_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.063852 (rank : 102)
Query Neighborhood Hits	220	Target Neighborhood Hits	1446	Shared Neighborhood Hits	95
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.065807 (rank : 99)
Query Neighborhood Hits	220	Target Neighborhood Hits	998	Shared Neighborhood Hits	92
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MUC1_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.067003 (rank : 95)
Query Neighborhood Hits	220	Target Neighborhood Hits	975	Shared Neighborhood Hits	71
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NCOA6_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.064591 (rank : 101)
Query Neighborhood Hits	220	Target Neighborhood Hits	1202	Shared Neighborhood Hits	96
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

OSB11_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.050152 (rank : 136)
Query Neighborhood Hits	220	Target Neighborhood Hits	60	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSBL3_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.066296 (rank : 97)
Query Neighborhood Hits	220	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL3_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.066425 (rank : 96)
Query Neighborhood Hits	220	Target Neighborhood Hits	86	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL9_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.073905 (rank : 83)
Query Neighborhood Hits	220	Target Neighborhood Hits	138	Shared Neighborhood Hits	37
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

PKHA3_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.084654 (rank : 65)
Query Neighborhood Hits	220	Target Neighborhood Hits	67	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PKHB2_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.054537 (rank : 121)
Query Neighborhood Hits	220	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

RASA3_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.078456 (rank : 73)
Query Neighborhood Hits	220	Target Neighborhood Hits	166	Shared Neighborhood Hits	28
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA3_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.076043 (rank : 78)
Query Neighborhood Hits	220	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RHG25_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.115761 (rank : 51)
Query Neighborhood Hits	220	Target Neighborhood Hits	492	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TARSH_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.068509 (rank : 94)
Query Neighborhood Hits	220	Target Neighborhood Hits	768	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TGON2_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.053276 (rank : 127)
Query Neighborhood Hits	220	Target Neighborhood Hits	1037	Shared Neighborhood Hits	74
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

WIRE_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.050715 (rank : 135)
Query Neighborhood Hits	220	Target Neighborhood Hits	310	Shared Neighborhood Hits	33
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ZIMP7_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.050786 (rank : 134)
Query Neighborhood Hits	220	Target Neighborhood Hits	290	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZIMP7_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.052275 (rank : 131)
Query Neighborhood Hits	220	Target Neighborhood Hits	566	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

Hits sorted by NC score

GAB2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	220	Target Neighborhood Hits	220	Shared Neighborhood Hits	220
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

GAB2_HUMAN
NC score	0.968699 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	220	Target Neighborhood Hits	188	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GAB1_MOUSE
NC score	0.872651 (rank : 3)	θ value	2.70778e-113 (rank : 4)
Query Neighborhood Hits	220	Target Neighborhood Hits	233	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_HUMAN
NC score	0.866376 (rank : 4)	θ value	2.70778e-113 (rank : 3)
Query Neighborhood Hits	220	Target Neighborhood Hits	279	Shared Neighborhood Hits	77
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PKHA1_MOUSE
NC score	0.402944 (rank : 5)	θ value	1.99992e-07 (rank : 5)
Query Neighborhood Hits	220	Target Neighborhood Hits	120	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_HUMAN
NC score	0.390192 (rank : 6)	θ value	7.59969e-07 (rank : 7)
Query Neighborhood Hits	220	Target Neighborhood Hits	127	Shared Neighborhood Hits	56
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_HUMAN
NC score	0.380448 (rank : 7)	θ value	9.92553e-07 (rank : 8)
Query Neighborhood Hits	220	Target Neighborhood Hits	119	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
NC score	0.376728 (rank : 8)	θ value	4.92598e-06 (rank : 13)
Query Neighborhood Hits	220	Target Neighborhood Hits	116	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PLEK_HUMAN
NC score	0.319716 (rank : 9)	θ value	9.29e-05 (rank : 18)
Query Neighborhood Hits	220	Target Neighborhood Hits	110	Shared Neighborhood Hits	48
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
NC score	0.314576 (rank : 10)	θ value	7.1131e-05 (rank : 16)
Query Neighborhood Hits	220	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

IRS1_HUMAN
NC score	0.253146 (rank : 11)	θ value	7.59969e-07 (rank : 6)
Query Neighborhood Hits	220	Target Neighborhood Hits	109	Shared Neighborhood Hits	24
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

DAPP1_MOUSE
NC score	0.247983 (rank : 12)	θ value	9.29e-05 (rank : 17)
Query Neighborhood Hits	220	Target Neighborhood Hits	225	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CNKR2_MOUSE
NC score	0.247861 (rank : 13)	θ value	1.43324e-05 (rank : 15)
Query Neighborhood Hits	220	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.247737 (rank : 14)	θ value	1.43324e-05 (rank : 14)
Query Neighborhood Hits	220	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

DAPP1_HUMAN
NC score	0.244912 (rank : 15)	θ value	0.000121331 (rank : 19)
Query Neighborhood Hits	220	Target Neighborhood Hits	227	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

IRS1_MOUSE
NC score	0.244278 (rank : 16)	θ value	2.21117e-06 (rank : 12)
Query Neighborhood Hits	220	Target Neighborhood Hits	112	Shared Neighborhood Hits	23
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

PHLB1_MOUSE
NC score	0.224793 (rank : 17)	θ value	0.000121331 (rank : 20)
Query Neighborhood Hits	220	Target Neighborhood Hits	678	Shared Neighborhood Hits	72
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CNKR1_HUMAN
NC score	0.223519 (rank : 18)	θ value	0.0736092 (rank : 49)
Query Neighborhood Hits	220	Target Neighborhood Hits	154	Shared Neighborhood Hits	44
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

PLEK2_HUMAN
NC score	0.206430 (rank : 19)	θ value	0.279714 (rank : 69)
Query Neighborhood Hits	220	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
NC score	0.206325 (rank : 20)	θ value	0.279714 (rank : 70)
Query Neighborhood Hits	220	Target Neighborhood Hits	96	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PHLB1_HUMAN
NC score	0.197775 (rank : 21)	θ value	0.00228821 (rank : 29)
Query Neighborhood Hits	220	Target Neighborhood Hits	1038	Shared Neighborhood Hits	88
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKHA5_HUMAN
NC score	0.180697 (rank : 22)	θ value	0.163984 (rank : 61)
Query Neighborhood Hits	220	Target Neighborhood Hits	455	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_MOUSE
NC score	0.180215 (rank : 23)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	220	Target Neighborhood Hits	591	Shared Neighborhood Hits	81
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PHLB2_HUMAN
NC score	0.177416 (rank : 24)	θ value	0.00035302 (rank : 23)
Query Neighborhood Hits	220	Target Neighborhood Hits	964	Shared Neighborhood Hits	58
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PKHA6_HUMAN
NC score	0.173162 (rank : 25)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	220	Target Neighborhood Hits	556	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PHLB2_MOUSE
NC score	0.172961 (rank : 26)	θ value	0.000270298 (rank : 22)
Query Neighborhood Hits	220	Target Neighborhood Hits	1016	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

MRIP_HUMAN
NC score	0.171316 (rank : 27)	θ value	0.000461057 (rank : 24)
Query Neighborhood Hits	220	Target Neighborhood Hits	578	Shared Neighborhood Hits	55
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MRIP_MOUSE
NC score	0.162815 (rank : 28)	θ value	0.00134147 (rank : 27)
Query Neighborhood Hits	220	Target Neighborhood Hits	569	Shared Neighborhood Hits	54
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

SRRM2_HUMAN
NC score	0.158963 (rank : 29)	θ value	0.00102713 (rank : 26)
Query Neighborhood Hits	220	Target Neighborhood Hits	1296	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
NC score	0.156996 (rank : 30)	θ value	9.92553e-07 (rank : 9)
Query Neighborhood Hits	220	Target Neighborhood Hits	1470	Shared Neighborhood Hits	99
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PKHA4_MOUSE
NC score	0.152442 (rank : 31)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	220	Target Neighborhood Hits	202	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

TARA_MOUSE
NC score	0.149883 (rank : 32)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	220	Target Neighborhood Hits	1133	Shared Neighborhood Hits	85
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

C43BP_MOUSE
NC score	0.149633 (rank : 33)	θ value	0.47712 (rank : 75)
Query Neighborhood Hits	220	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

IRS2_MOUSE
NC score	0.149144 (rank : 34)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	220	Target Neighborhood Hits	248	Shared Neighborhood Hits	37
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

PKHA4_HUMAN
NC score	0.146778 (rank : 35)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	220	Target Neighborhood Hits	283	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

IRS2_HUMAN
NC score	0.142731 (rank : 36)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	220	Target Neighborhood Hits	262	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

DOC10_HUMAN
NC score	0.141770 (rank : 37)	θ value	1.69304e-06 (rank : 10)
Query Neighborhood Hits	220	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q96BY6, O75178, Q9NW06, Q9NXI8	Gene names	DOCK10, KIAA0694
Domain Architecture
Description	Dedicator of cytokinesis protein 10 (Protein zizimin 3).

CEND1_HUMAN
NC score	0.139509 (rank : 38)	θ value	0.00509761 (rank : 31)
Query Neighborhood Hits	220	Target Neighborhood Hits	284	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

RHG25_HUMAN
NC score	0.138359 (rank : 39)	θ value	0.000602161 (rank : 25)
Query Neighborhood Hits	220	Target Neighborhood Hits	550	Shared Neighborhood Hits	58
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TARA_HUMAN
NC score	0.138079 (rank : 40)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	220	Target Neighborhood Hits	1626	Shared Neighborhood Hits	116
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CEND2_HUMAN
NC score	0.136022 (rank : 41)	θ value	0.000270298 (rank : 21)
Query Neighborhood Hits	220	Target Neighborhood Hits	166	Shared Neighborhood Hits	38
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

RASA1_HUMAN
NC score	0.135013 (rank : 42)	θ value	0.0252991 (rank : 40)
Query Neighborhood Hits	220	Target Neighborhood Hits	258	Shared Neighborhood Hits	39
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

SWP70_MOUSE
NC score	0.133349 (rank : 43)	θ value	0.0252991 (rank : 42)
Query Neighborhood Hits	220	Target Neighborhood Hits	1097	Shared Neighborhood Hits	65
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_HUMAN
NC score	0.132875 (rank : 44)	θ value	0.0148317 (rank : 37)
Query Neighborhood Hits	220	Target Neighborhood Hits	973	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

RASA2_MOUSE
NC score	0.131000 (rank : 45)	θ value	0.00175202 (rank : 28)
Query Neighborhood Hits	220	Target Neighborhood Hits	159	Shared Neighborhood Hits	30
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

C43BP_HUMAN
NC score	0.130036 (rank : 46)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	220	Target Neighborhood Hits	87	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

RPB1_MOUSE
NC score	0.127524 (rank : 47)	θ value	0.0148317 (rank : 35)
Query Neighborhood Hits	220	Target Neighborhood Hits	363	Shared Neighborhood Hits	36
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.127284 (rank : 48)	θ value	0.0148317 (rank : 34)
Query Neighborhood Hits	220	Target Neighborhood Hits	362	Shared Neighborhood Hits	35
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

MYO10_HUMAN
NC score	0.120194 (rank : 49)	θ value	1.69304e-06 (rank : 11)
Query Neighborhood Hits	220	Target Neighborhood Hits	920	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MTMR5_HUMAN
NC score	0.116872 (rank : 50)	θ value	0.0563607 (rank : 48)
Query Neighborhood Hits	220	Target Neighborhood Hits	141	Shared Neighborhood Hits	37
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

RHG25_MOUSE
NC score	0.115761 (rank : 51)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	220	Target Neighborhood Hits	492	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

DOCK9_MOUSE
NC score	0.115411 (rank : 52)	θ value	0.0330416 (rank : 45)
Query Neighborhood Hits	220	Target Neighborhood Hits	79	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BIK4, Q921Y6	Gene names	Dock9, D14Wsu89e, Kiaa1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

TBCD2_HUMAN
NC score	0.113245 (rank : 53)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	220	Target Neighborhood Hits	419	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

RASA2_HUMAN
NC score	0.110295 (rank : 54)	θ value	0.0330416 (rank : 46)
Query Neighborhood Hits	220	Target Neighborhood Hits	157	Shared Neighborhood Hits	26
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

CEND1_MOUSE
NC score	0.110243 (rank : 55)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	220	Target Neighborhood Hits	260	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

OSBP1_HUMAN
NC score	0.109431 (rank : 56)	θ value	0.00390308 (rank : 30)
Query Neighborhood Hits	220	Target Neighborhood Hits	180	Shared Neighborhood Hits	44
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

MTMRD_HUMAN
NC score	0.107207 (rank : 57)	θ value	0.163984 (rank : 60)
Query Neighborhood Hits	220	Target Neighborhood Hits	135	Shared Neighborhood Hits	42
SwissProt Accessions	Q86WG5, Q3MJF0, Q68DQ3, Q6P459, Q6PJD1, Q7Z325, Q7Z621, Q86VE2, Q96FE2, Q9C097	Gene names	SBF2, CMT4B2, KIAA1766, MTMR13
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 13 (SET-binding factor 2).

OSBP2_MOUSE
NC score	0.105862 (rank : 58)	θ value	0.125558 (rank : 57)
Query Neighborhood Hits	220	Target Neighborhood Hits	150	Shared Neighborhood Hits	46
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

DOCK9_HUMAN
NC score	0.103828 (rank : 59)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	220	Target Neighborhood Hits	82	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZ29, Q5JUD4, Q5JUD6, Q5T2Q1, Q5TAN8, Q9BZ25, Q9BZ26, Q9BZ27, Q9BZ28, Q9UPU4	Gene names	DOCK9, KIAA1058
Domain Architecture
Description	Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin 1).

OSBP2_HUMAN
NC score	0.097851 (rank : 60)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	220	Target Neighborhood Hits	154	Shared Neighborhood Hits	46
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

SRRM1_MOUSE
NC score	0.090887 (rank : 61)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	220	Target Neighborhood Hits	966	Shared Neighborhood Hits	73
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PKHA3_HUMAN
NC score	0.088908 (rank : 62)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	220	Target Neighborhood Hits	66	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

WASIP_MOUSE
NC score	0.086085 (rank : 63)	θ value	0.62314 (rank : 90)
Query Neighborhood Hits	220	Target Neighborhood Hits	392	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

NACAM_MOUSE
NC score	0.084962 (rank : 64)	θ value	0.47712 (rank : 79)
Query Neighborhood Hits	220	Target Neighborhood Hits	1866	Shared Neighborhood Hits	111
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PKHA3_MOUSE
NC score	0.084654 (rank : 65)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	220	Target Neighborhood Hits	67	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

SRRM1_HUMAN
NC score	0.083523 (rank : 66)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	220	Target Neighborhood Hits	690	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CT174_HUMAN
NC score	0.083172 (rank : 67)	θ value	0.0330416 (rank : 44)
Query Neighborhood Hits	220	Target Neighborhood Hits	181	Shared Neighborhood Hits	27
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

CYH1_HUMAN
NC score	0.081994 (rank : 68)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	220	Target Neighborhood Hits	184	Shared Neighborhood Hits	51
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

SGIP1_MOUSE
NC score	0.081780 (rank : 69)	θ value	0.163984 (rank : 62)
Query Neighborhood Hits	220	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

RAPH1_HUMAN
NC score	0.080721 (rank : 70)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	220	Target Neighborhood Hits	593	Shared Neighborhood Hits	52
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

CYH1_MOUSE
NC score	0.079488 (rank : 71)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	220	Target Neighborhood Hits	176	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

PYGO1_HUMAN
NC score	0.078993 (rank : 72)	θ value	0.279714 (rank : 71)
Query Neighborhood Hits	220	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

RASA3_HUMAN
NC score	0.078456 (rank : 73)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	220	Target Neighborhood Hits	166	Shared Neighborhood Hits	28
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

CENB2_HUMAN
NC score	0.077515 (rank : 74)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	220	Target Neighborhood Hits	425	Shared Neighborhood Hits	46
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CYH3_MOUSE
NC score	0.076982 (rank : 75)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	220	Target Neighborhood Hits	148	Shared Neighborhood Hits	48
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

SGIP1_HUMAN
NC score	0.076845 (rank : 76)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	220	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

CS007_MOUSE
NC score	0.076196 (rank : 77)	θ value	0.0113563 (rank : 33)
Query Neighborhood Hits	220	Target Neighborhood Hits	464	Shared Neighborhood Hits	36
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

RASA3_MOUSE
NC score	0.076043 (rank : 78)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	220	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

CYH4_HUMAN
NC score	0.074360 (rank : 79)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	220	Target Neighborhood Hits	135	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH2_HUMAN
NC score	0.074299 (rank : 80)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	220	Target Neighborhood Hits	175	Shared Neighborhood Hits	49
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.074290 (rank : 81)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	220	Target Neighborhood Hits	171	Shared Neighborhood Hits	49
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CENB5_HUMAN
NC score	0.074232 (rank : 82)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	220	Target Neighborhood Hits	395	Shared Neighborhood Hits	47
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

OSBL9_HUMAN
NC score	0.073905 (rank : 83)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	220	Target Neighborhood Hits	138	Shared Neighborhood Hits	37
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

CYH4_MOUSE
NC score	0.073190 (rank : 84)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	220	Target Neighborhood Hits	134	Shared Neighborhood Hits	46
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

ZIM10_MOUSE
NC score	0.072534 (rank : 85)	θ value	0.00665767 (rank : 32)
Query Neighborhood Hits	220	Target Neighborhood Hits	430	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIM10_HUMAN
NC score	0.072305 (rank : 86)	θ value	0.0252991 (rank : 43)
Query Neighborhood Hits	220	Target Neighborhood Hits	577	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CEND3_HUMAN
NC score	0.072201 (rank : 87)	θ value	6.88961 (rank : 184)
Query Neighborhood Hits	220	Target Neighborhood Hits	275	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

MUC15_MOUSE
NC score	0.071798 (rank : 88)	θ value	0.47712 (rank : 78)
Query Neighborhood Hits	220	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C6Z1, Q3UQC4, Q6XYQ9, Q7TMH6, Q8CE82	Gene names	Muc15
Domain Architecture	No domain graphic available
Description	Mucin-15 precursor.

CENB1_HUMAN
NC score	0.070607 (rank : 89)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	220	Target Neighborhood Hits	383	Shared Neighborhood Hits	42
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

BCL9_HUMAN
NC score	0.070337 (rank : 90)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	220	Target Neighborhood Hits	1008	Shared Neighborhood Hits	74
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CYH3_HUMAN
NC score	0.069840 (rank : 91)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	220	Target Neighborhood Hits	137	Shared Neighborhood Hits	45
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

WASIP_HUMAN
NC score	0.068914 (rank : 92)	θ value	6.88961 (rank : 200)
Query Neighborhood Hits	220	Target Neighborhood Hits	458	Shared Neighborhood Hits	37
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

CEND3_MOUSE
NC score	0.068562 (rank : 93)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	220	Target Neighborhood Hits	228	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

TARSH_HUMAN
NC score	0.068509 (rank : 94)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	220	Target Neighborhood Hits	768	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MUC1_HUMAN
NC score	0.067003 (rank : 95)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	220	Target Neighborhood Hits	975	Shared Neighborhood Hits	71
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

OSBL3_MOUSE
NC score	0.066425 (rank : 96)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	220	Target Neighborhood Hits	86	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL3_HUMAN
NC score	0.066296 (rank : 97)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	220	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

SETBP_MOUSE
NC score	0.066155 (rank : 98)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	220	Target Neighborhood Hits	352	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

MDC1_MOUSE
NC score	0.065807 (rank : 99)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	220	Target Neighborhood Hits	998	Shared Neighborhood Hits	92
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

WIRE_HUMAN
NC score	0.065762 (rank : 100)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	220	Target Neighborhood Hits	329	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

NCOA6_HUMAN
NC score	0.064591 (rank : 101)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	220	Target Neighborhood Hits	1202	Shared Neighborhood Hits	96
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MDC1_HUMAN
NC score	0.063852 (rank : 102)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	220	Target Neighborhood Hits	1446	Shared Neighborhood Hits	95
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

BCL9_MOUSE
NC score	0.063345 (rank : 103)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	220	Target Neighborhood Hits	770	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

3BP2_HUMAN
NC score	0.062596 (rank : 104)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	220	Target Neighborhood Hits	296	Shared Neighborhood Hits	44
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

BSN_HUMAN
NC score	0.062175 (rank : 105)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	220	Target Neighborhood Hits	1537	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

NOLC1_HUMAN
NC score	0.061294 (rank : 106)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	220	Target Neighborhood Hits	452	Shared Neighborhood Hits	24
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

OSBL6_MOUSE
NC score	0.060235 (rank : 107)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	220	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

LCP2_HUMAN
NC score	0.060067 (rank : 108)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	220	Target Neighborhood Hits	531	Shared Neighborhood Hits	59
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

OSBL6_HUMAN
NC score	0.059873 (rank : 109)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	220	Target Neighborhood Hits	101	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

PEX5R_HUMAN
NC score	0.059290 (rank : 110)	θ value	0.0961366 (rank : 51)
Query Neighborhood Hits	220	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IYB4, Q9NQD1, Q9P2U3, Q9P2U4	Gene names	PEX5L, PEX5R, PXR2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

ENAH_MOUSE
NC score	0.059265 (rank : 111)	θ value	0.279714 (rank : 68)
Query Neighborhood Hits	220	Target Neighborhood Hits	919	Shared Neighborhood Hits	52
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

OSB11_MOUSE
NC score	0.058917 (rank : 112)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	220	Target Neighborhood Hits	71	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

DGKH_HUMAN
NC score	0.057771 (rank : 113)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	220	Target Neighborhood Hits	255	Shared Neighborhood Hits	43
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

MAGC1_HUMAN
NC score	0.057541 (rank : 114)	θ value	0.0252991 (rank : 39)
Query Neighborhood Hits	220	Target Neighborhood Hits	431	Shared Neighborhood Hits	37
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

PCLO_HUMAN
NC score	0.056932 (rank : 115)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	220	Target Neighborhood Hits	2046	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

K0460_HUMAN
NC score	0.056274 (rank : 116)	θ value	0.47712 (rank : 77)
Query Neighborhood Hits	220	Target Neighborhood Hits	357	Shared Neighborhood Hits	29
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

RASL1_MOUSE
NC score	0.056167 (rank : 117)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	220	Target Neighborhood Hits	148	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

AFF1_HUMAN
NC score	0.056059 (rank : 118)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	220	Target Neighborhood Hits	506	Shared Neighborhood Hits	35
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

BSN_MOUSE
NC score	0.055094 (rank : 119)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	220	Target Neighborhood Hits	2057	Shared Neighborhood Hits	111
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PER3_HUMAN
NC score	0.054648 (rank : 120)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	220	Target Neighborhood Hits	479	Shared Neighborhood Hits	43
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PKHB2_MOUSE
NC score	0.054537 (rank : 121)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	220	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

BTBDC_HUMAN
NC score	0.054349 (rank : 122)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	220	Target Neighborhood Hits	248	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

3BP2_MOUSE
NC score	0.054283 (rank : 123)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	220	Target Neighborhood Hits	142	Shared Neighborhood Hits	23
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

FILA_HUMAN
NC score	0.054222 (rank : 124)	θ value	0.0252991 (rank : 38)
Query Neighborhood Hits	220	Target Neighborhood Hits	685	Shared Neighborhood Hits	28
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

SETBP_HUMAN
NC score	0.053812 (rank : 125)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	220	Target Neighborhood Hits	305	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

RUNX2_HUMAN
NC score	0.053309 (rank : 126)	θ value	0.0961366 (rank : 53)
Query Neighborhood Hits	220	Target Neighborhood Hits	103	Shared Neighborhood Hits	15
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

TGON2_HUMAN
NC score	0.053276 (rank : 127)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	220	Target Neighborhood Hits	1037	Shared Neighborhood Hits	74
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SC24D_HUMAN
NC score	0.052927 (rank : 128)	θ value	0.0736092 (rank : 50)
Query Neighborhood Hits	220	Target Neighborhood Hits	173	Shared Neighborhood Hits	15
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

MAGE1_HUMAN
NC score	0.052474 (rank : 129)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	220	Target Neighborhood Hits	1389	Shared Neighborhood Hits	101
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CENA2_MOUSE
NC score	0.052361 (rank : 130)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	220	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

ZIMP7_MOUSE
NC score	0.052275 (rank : 131)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	220	Target Neighborhood Hits	566	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

CENA2_HUMAN
NC score	0.052155 (rank : 132)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	220	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENA1_HUMAN
NC score	0.051287 (rank : 133)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	220	Target Neighborhood Hits	87	Shared Neighborhood Hits	33
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

ZIMP7_HUMAN
NC score	0.050786 (rank : 134)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	220	Target Neighborhood Hits	290	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

WIRE_MOUSE
NC score	0.050715 (rank : 135)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	220	Target Neighborhood Hits	310	Shared Neighborhood Hits	33
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

OSB11_HUMAN
NC score	0.050152 (rank : 136)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	220	Target Neighborhood Hits	60	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

GPTC8_HUMAN
NC score	0.050098 (rank : 137)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	220	Target Neighborhood Hits	366	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

SHAN1_HUMAN
NC score	0.049728 (rank : 138)	θ value	0.0148317 (rank : 36)
Query Neighborhood Hits	220	Target Neighborhood Hits	1041	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

RUNX2_MOUSE
NC score	0.049696 (rank : 139)	θ value	0.279714 (rank : 72)
Query Neighborhood Hits	220	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

REXO1_HUMAN
NC score	0.049093 (rank : 140)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	220	Target Neighborhood Hits	242	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

ARI1A_HUMAN
NC score	0.048509 (rank : 141)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	220	Target Neighborhood Hits	787	Shared Neighborhood Hits	56
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

AUTS2_HUMAN
NC score	0.047333 (rank : 142)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	220	Target Neighborhood Hits	342	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

TENS1_HUMAN
NC score	0.047286 (rank : 143)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	220	Target Neighborhood Hits	400	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

DOK2_MOUSE
NC score	0.047141 (rank : 144)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	220	Target Neighborhood Hits	244	Shared Neighborhood Hits	29
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

PRR12_HUMAN
NC score	0.046394 (rank : 145)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	220	Target Neighborhood Hits	460	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

TACC2_MOUSE
NC score	0.046161 (rank : 146)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	220	Target Neighborhood Hits	774	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TTC16_HUMAN
NC score	0.045393 (rank : 147)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	220	Target Neighborhood Hits	417	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

ENAH_HUMAN
NC score	0.044923 (rank : 148)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	220	Target Neighborhood Hits	784	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

AF17_HUMAN
NC score	0.044414 (rank : 149)	θ value	0.163984 (rank : 58)
Query Neighborhood Hits	220	Target Neighborhood Hits	230	Shared Neighborhood Hits	20
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

MUC2_HUMAN
NC score	0.043581 (rank : 150)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	220	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SYNP2_HUMAN
NC score	0.042689 (rank : 151)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	220	Target Neighborhood Hits	323	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

CIC_MOUSE
NC score	0.042262 (rank : 152)	θ value	0.279714 (rank : 67)
Query Neighborhood Hits	220	Target Neighborhood Hits	742	Shared Neighborhood Hits	64
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ZDHC8_HUMAN
NC score	0.041221 (rank : 153)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	220	Target Neighborhood Hits	234	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

SYNJ1_HUMAN
NC score	0.040809 (rank : 154)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	220	Target Neighborhood Hits	498	Shared Neighborhood Hits	38
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ZDHC8_MOUSE
NC score	0.040589 (rank : 155)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	220	Target Neighborhood Hits	243	Shared Neighborhood Hits	25
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

EMSY_MOUSE
NC score	0.040239 (rank : 156)	θ value	0.163984 (rank : 59)
Query Neighborhood Hits	220	Target Neighborhood Hits	294	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

SET1A_HUMAN
NC score	0.040055 (rank : 157)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	220	Target Neighborhood Hits	690	Shared Neighborhood Hits	36
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

K0586_HUMAN
NC score	0.039406 (rank : 158)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	220	Target Neighborhood Hits	311	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

K0310_HUMAN
NC score	0.039153 (rank : 159)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	220	Target Neighborhood Hits	420	Shared Neighborhood Hits	43
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

SF3A1_HUMAN
NC score	0.039042 (rank : 160)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	220	Target Neighborhood Hits	199	Shared Neighborhood Hits	18
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

AF9_HUMAN
NC score	0.038888 (rank : 161)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	220	Target Neighborhood Hits	202	Shared Neighborhood Hits	18
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

PI5PA_HUMAN
NC score	0.038590 (rank : 162)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	220	Target Neighborhood Hits	749	Shared Neighborhood Hits	60
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

AFF1_MOUSE
NC score	0.037988 (rank : 163)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	220	Target Neighborhood Hits	351	Shared Neighborhood Hits	18
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

AFF4_MOUSE
NC score	0.037843 (rank : 164)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	220	Target Neighborhood Hits	581	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

DDFL1_HUMAN
NC score	0.037011 (rank : 165)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	220	Target Neighborhood Hits	353	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

BLNK_HUMAN
NC score	0.036921 (rank : 166)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	220	Target Neighborhood Hits	228	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

MINT_HUMAN
NC score	0.036567 (rank : 167)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	220	Target Neighborhood Hits	1291	Shared Neighborhood Hits	61
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

DCP1A_MOUSE
NC score	0.036520 (rank : 168)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	220	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

SF3A1_MOUSE
NC score	0.035930 (rank : 169)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	220	Target Neighborhood Hits	198	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

JIP3_HUMAN
NC score	0.035027 (rank : 170)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	220	Target Neighborhood Hits	1039	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

SYNP2_MOUSE
NC score	0.034454 (rank : 171)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	220	Target Neighborhood Hits	252	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

AF10_HUMAN
NC score	0.033882 (rank : 172)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	220	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

FARP1_HUMAN
NC score	0.033387 (rank : 173)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	220	Target Neighborhood Hits	241	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

DOK2_HUMAN
NC score	0.033238 (rank : 174)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	220	Target Neighborhood Hits	46	Shared Neighborhood Hits	7
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

UBP29_HUMAN
NC score	0.032449 (rank : 175)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	220	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

SHPS1_HUMAN
NC score	0.032153 (rank : 176)	θ value	0.0252991 (rank : 41)
Query Neighborhood Hits	220	Target Neighborhood Hits	455	Shared Neighborhood Hits	5
SwissProt Accessions	P78324, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9	Gene names	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (Sirp-alpha-2) (Sirp-alpha- 3) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusion receptor) (p84) (CD172a antigen).

CASC5_MOUSE
NC score	0.029969 (rank : 177)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	220	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

REPS2_MOUSE
NC score	0.029752 (rank : 178)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	220	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

HRX_HUMAN
NC score	0.029090 (rank : 179)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	220	Target Neighborhood Hits	825	Shared Neighborhood Hits	49
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MAP4_MOUSE
NC score	0.028835 (rank : 180)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	220	Target Neighborhood Hits	409	Shared Neighborhood Hits	34
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

GCX1_HUMAN
NC score	0.028593 (rank : 181)	θ value	1.38821 (rank : 110)
Query Neighborhood Hits	220	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

CCDC4_HUMAN
NC score	0.027711 (rank : 182)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	220	Target Neighborhood Hits	104	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

LDB3_MOUSE
NC score	0.027518 (rank : 183)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	220	Target Neighborhood Hits	510	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

ZO1_MOUSE
NC score	0.026866 (rank : 184)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	220	Target Neighborhood Hits	453	Shared Neighborhood Hits	34
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZDHC5_MOUSE
NC score	0.026425 (rank : 185)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	220	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VDZ4, Q69ZB5, Q8R2X7	Gene names	Zdhhc5, Kiaa1748
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5).

T240L_MOUSE
NC score	0.025965 (rank : 186)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	220	Target Neighborhood Hits	143	Shared Neighborhood Hits	11
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

TENS4_MOUSE
NC score	0.025647 (rank : 187)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	220	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

SFPQ_MOUSE
NC score	0.025617 (rank : 188)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	220	Target Neighborhood Hits	958	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

ZDHC5_HUMAN
NC score	0.025410 (rank : 189)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	220	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0B5, Q6ZMF0, Q8TAK8, Q9H923, Q9UFI7	Gene names	ZDHHC5, KIAA1748, ZNF375
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC5 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375).

SDC1_HUMAN
NC score	0.025120 (rank : 190)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	220	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	P18827, Q96HB7	Gene names	SDC1, SDC
Domain Architecture
Description	Syndecan-1 precursor (SYND1) (CD138 antigen).

PDLI5_MOUSE
NC score	0.024938 (rank : 191)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	220	Target Neighborhood Hits	287	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

GFRA2_HUMAN
NC score	0.024917 (rank : 192)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	220	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

LDB3_HUMAN
NC score	0.024730 (rank : 193)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	220	Target Neighborhood Hits	497	Shared Neighborhood Hits	33
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

SPT6H_MOUSE
NC score	0.024321 (rank : 194)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	220	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

HN1_HUMAN
NC score	0.023862 (rank : 195)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	220	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK76, Q53FG7, Q7Z2D2, Q7Z2F0	Gene names	HN1, ARM2
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1 protein (Androgen-regulated protein 2).

SPT6H_HUMAN
NC score	0.023767 (rank : 196)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	220	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

BAZ2B_HUMAN
NC score	0.023698 (rank : 197)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	220	Target Neighborhood Hits	803	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

MYO15_HUMAN
NC score	0.023443 (rank : 198)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	220	Target Neighborhood Hits	671	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

UBN1_HUMAN
NC score	0.022488 (rank : 199)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	220	Target Neighborhood Hits	170	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

GFRA2_MOUSE
NC score	0.022294 (rank : 200)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	220	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

PDE3A_MOUSE
NC score	0.021980 (rank : 201)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	220	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

AP180_MOUSE
NC score	0.021674 (rank : 202)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	220	Target Neighborhood Hits	194	Shared Neighborhood Hits	13
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

KIF1A_MOUSE
NC score	0.021544 (rank : 203)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	220	Target Neighborhood Hits	239	Shared Neighborhood Hits	18
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

BRDT_MOUSE
NC score	0.021116 (rank : 204)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	220	Target Neighborhood Hits	243	Shared Neighborhood Hits	15
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

GNAS1_MOUSE
NC score	0.020528 (rank : 205)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	220	Target Neighborhood Hits	651	Shared Neighborhood Hits	45
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

ICB1_MOUSE
NC score	0.020293 (rank : 206)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	220	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

MAST4_HUMAN
NC score	0.019086 (rank : 207)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	220	Target Neighborhood Hits	1804	Shared Neighborhood Hits	83
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

WNK4_HUMAN
NC score	0.018683 (rank : 208)	θ value	0.279714 (rank : 73)
Query Neighborhood Hits	220	Target Neighborhood Hits	1043	Shared Neighborhood Hits	35
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

BRDT_HUMAN
NC score	0.018664 (rank : 209)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	220	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

PER1_MOUSE
NC score	0.018284 (rank : 210)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	220	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

FA53C_MOUSE
NC score	0.018141 (rank : 211)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	220	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BXQ8, Q3U4J2	Gene names	Fam53c
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

KIFC3_HUMAN
NC score	0.017228 (rank : 212)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	220	Target Neighborhood Hits	619	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

CROCC_HUMAN
NC score	0.017118 (rank : 213)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	220	Target Neighborhood Hits	1409	Shared Neighborhood Hits	40
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

T240L_HUMAN
NC score	0.017044 (rank : 214)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	220	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

RAI14_MOUSE
NC score	0.016750 (rank : 215)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	220	Target Neighborhood Hits	1505	Shared Neighborhood Hits	53
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

KIF1A_HUMAN
NC score	0.016643 (rank : 216)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	220	Target Neighborhood Hits	240	Shared Neighborhood Hits	17
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

CSKI2_MOUSE
NC score	0.016583 (rank : 217)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	220	Target Neighborhood Hits	812	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

UBP31_HUMAN
NC score	0.016491 (rank : 218)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	220	Target Neighborhood Hits	293	Shared Neighborhood Hits	17
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

GA2L1_HUMAN
NC score	0.016449 (rank : 219)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	220	Target Neighborhood Hits	177	Shared Neighborhood Hits	15
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

SOX15_HUMAN
NC score	0.016409 (rank : 220)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	220	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

IP3KC_MOUSE
NC score	0.016084 (rank : 221)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	220	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TS72, Q3U384	Gene names	Itpkc
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (IP3K-C).

HCN4_MOUSE
NC score	0.015791 (rank : 222)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	220	Target Neighborhood Hits	284	Shared Neighborhood Hits	18
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

RIMB2_HUMAN
NC score	0.015285 (rank : 223)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	220	Target Neighborhood Hits	263	Shared Neighborhood Hits	9
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ROBO1_HUMAN
NC score	0.014895 (rank : 224)	θ value	0.0961366 (rank : 52)
Query Neighborhood Hits	220	Target Neighborhood Hits	529	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

WNK4_MOUSE
NC score	0.014869 (rank : 225)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	220	Target Neighborhood Hits	961	Shared Neighborhood Hits	31
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

RAD18_HUMAN
NC score	0.014741 (rank : 226)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	220	Target Neighborhood Hits	284	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

CABL2_MOUSE
NC score	0.014628 (rank : 227)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	220	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

CD2AP_MOUSE
NC score	0.013650 (rank : 228)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	220	Target Neighborhood Hits	336	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

SCMH1_MOUSE
NC score	0.013346 (rank : 229)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	220	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K214, Q9JME0	Gene names	Scmh1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

ATF7_MOUSE
NC score	0.013024 (rank : 230)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	220	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ROBO1_MOUSE
NC score	0.012678 (rank : 231)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	220	Target Neighborhood Hits	559	Shared Neighborhood Hits	12
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

MACF1_MOUSE
NC score	0.012487 (rank : 232)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	220	Target Neighborhood Hits	1313	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

EFCB3_MOUSE
NC score	0.012234 (rank : 233)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	220	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q80X60	Gene names	Efcab3
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 3.

CD2L7_HUMAN
NC score	0.011540 (rank : 234)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	220	Target Neighborhood Hits	1275	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CD2L5_MOUSE
NC score	0.011428 (rank : 235)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	220	Target Neighborhood Hits	1011	Shared Neighborhood Hits	31
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

GGA3_MOUSE
NC score	0.011293 (rank : 236)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	220	Target Neighborhood Hits	148	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

ASSY_MOUSE
NC score	0.011068 (rank : 237)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	220	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	P16460	Gene names	Ass1, Ass
Domain Architecture
Description	Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase).

MAST3_HUMAN
NC score	0.011046 (rank : 238)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	220	Target Neighborhood Hits	1128	Shared Neighborhood Hits	38
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

CD2L5_HUMAN
NC score	0.010935 (rank : 239)	θ value	0.47712 (rank : 76)
Query Neighborhood Hits	220	Target Neighborhood Hits	987	Shared Neighborhood Hits	30
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

CAP1_MOUSE
NC score	0.008836 (rank : 240)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	220	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P40124	Gene names	Cap1, Cap
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

RNAS7_HUMAN
NC score	0.008516 (rank : 241)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	220	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H1E1, P80927, P83685	Gene names	RNASE7
Domain Architecture
Description	Ribonuclease 7 precursor (EC 3.1.27.-) (RNase 7) (Skin-derived antimicrobial protein 2) (SAP-2).

ABL1_HUMAN
NC score	0.008320 (rank : 242)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	220	Target Neighborhood Hits	1220	Shared Neighborhood Hits	37
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

SPIB_MOUSE
NC score	0.007666 (rank : 243)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	220	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	O35906, O35907, O35909, O55199	Gene names	Spib
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-B.

FLNB_HUMAN
NC score	0.007368 (rank : 244)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	220	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

NR1D1_HUMAN
NC score	0.007052 (rank : 245)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	220	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

VDR_MOUSE
NC score	0.006805 (rank : 246)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	220	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

EGFR_HUMAN
NC score	0.006674 (rank : 247)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	220	Target Neighborhood Hits	939	Shared Neighborhood Hits	18
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

ZN335_HUMAN
NC score	0.006408 (rank : 248)	θ value	0.0330416 (rank : 47)
Query Neighborhood Hits	220	Target Neighborhood Hits	973	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

ROCK1_HUMAN
NC score	0.006342 (rank : 249)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	220	Target Neighborhood Hits	2000	Shared Neighborhood Hits	42
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

KPCD1_HUMAN
NC score	0.006254 (rank : 250)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	220	Target Neighborhood Hits	901	Shared Neighborhood Hits	17
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

MINK1_MOUSE
NC score	0.005531 (rank : 251)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	220	Target Neighborhood Hits	1451	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

SP4_MOUSE
NC score	0.004954 (rank : 252)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	220	Target Neighborhood Hits	759	Shared Neighborhood Hits	11
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

EGFR_MOUSE
NC score	0.004630 (rank : 253)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	220	Target Neighborhood Hits	927	Shared Neighborhood Hits	18
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

CUBN_MOUSE
NC score	0.004629 (rank : 254)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	220	Target Neighborhood Hits	477	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CHD1_MOUSE
NC score	0.004547 (rank : 255)	θ value	6.88961 (rank : 185)
Query Neighborhood Hits	220	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SP4_HUMAN
NC score	0.002949 (rank : 256)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	220	Target Neighborhood Hits	749	Shared Neighborhood Hits	9
SwissProt Accessions	Q02446, O60402	Gene names	SP4
Domain Architecture
Description	Transcription factor Sp4 (SPR-1).

HXD9_HUMAN
NC score	0.002149 (rank : 257)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	220	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	P28356	Gene names	HOXD9, HOX4C
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2).

ZN408_HUMAN
NC score	-0.002980 (rank : 258)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	220	Target Neighborhood Hits	775	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).