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Network neighborhood for query Sequence : GFRA2_MOUSE

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GFRA2_MOUSE
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GFRA2_HUMAN
θ value	0 (rank : 1)	NC score	0.999379 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

GFRA2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

GFRA1_MOUSE
θ value	1.53401e-116 (rank : 3)	NC score	0.975010 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P97785	Gene names	Gfra1, Gdnfra, Trnr1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1).

GFRA1_HUMAN
θ value	2.89301e-115 (rank : 4)	NC score	0.975624 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	P56159, O15507, O43912	Gene names	GFRA1, GDNFRA, RETL1, TRNR1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1) (RET ligand 1).

GFRA3_MOUSE
θ value	1.36585e-56 (rank : 5)	NC score	0.921732 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA3_HUMAN
θ value	1.56274e-52 (rank : 6)	NC score	0.915597 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA4_MOUSE
θ value	4.40402e-47 (rank : 7)	NC score	0.936697 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJT2, Q9JJT3, Q9JJT4, Q9JJT6, Q9JJT7, Q9JJT8	Gene names	Gfra4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA4_HUMAN
θ value	1.79631e-32 (rank : 8)	NC score	0.907099 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZZ7, Q9H191, Q9H192	Gene names	GFRA4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRAL_HUMAN
θ value	1.74796e-11 (rank : 9)	NC score	0.606670 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UXV0, Q5VTF6	Gene names	GFRAL
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GFRAL_MOUSE
θ value	7.34386e-10 (rank : 10)	NC score	0.585506 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

ZFY16_HUMAN
θ value	0.163984 (rank : 11)	NC score	0.032807 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

MASP2_HUMAN
θ value	0.62314 (rank : 12)	NC score	0.011014 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	364	Shared Neighborhood Hits	6
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

DOC2G_MOUSE
θ value	1.38821 (rank : 13)	NC score	0.017967 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

WISP3_HUMAN
θ value	2.36792 (rank : 14)	NC score	0.021752 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

GAB2_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.022294 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

RECK_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.020999 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

CNTP4_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.010577 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	187	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

EFHC2_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.014340 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JST6, Q5JST8, Q68DK4, Q8NEI0, Q9H653	Gene names	EFHC2
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member C2.

MKRN2_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.014049 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

PLAP_MOUSE
θ value	5.27518 (rank : 20)	NC score	0.009530 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

RAG1_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.014706 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	203	Shared Neighborhood Hits	3
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

FBN2_MOUSE
θ value	6.88961 (rank : 22)	NC score	0.003536 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	549	Shared Neighborhood Hits	7
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

JAG1_MOUSE
θ value	6.88961 (rank : 23)	NC score	0.004788 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	518	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

NOV_MOUSE
θ value	6.88961 (rank : 24)	NC score	0.014858 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	130	Shared Neighborhood Hits	6
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

SUSD1_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.012260 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

Hits sorted by NC score

GFRA2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

GFRA2_HUMAN
NC score	0.999379 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

GFRA1_HUMAN
NC score	0.975624 (rank : 3)	θ value	2.89301e-115 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	P56159, O15507, O43912	Gene names	GFRA1, GDNFRA, RETL1, TRNR1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1) (RET ligand 1).

GFRA1_MOUSE
NC score	0.975010 (rank : 4)	θ value	1.53401e-116 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P97785	Gene names	Gfra1, Gdnfra, Trnr1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1).

GFRA4_MOUSE
NC score	0.936697 (rank : 5)	θ value	4.40402e-47 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJT2, Q9JJT3, Q9JJT4, Q9JJT6, Q9JJT7, Q9JJT8	Gene names	Gfra4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA3_MOUSE
NC score	0.921732 (rank : 6)	θ value	1.36585e-56 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA3_HUMAN
NC score	0.915597 (rank : 7)	θ value	1.56274e-52 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA4_HUMAN
NC score	0.907099 (rank : 8)	θ value	1.79631e-32 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZZ7, Q9H191, Q9H192	Gene names	GFRA4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRAL_HUMAN
NC score	0.606670 (rank : 9)	θ value	1.74796e-11 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UXV0, Q5VTF6	Gene names	GFRAL
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GFRAL_MOUSE
NC score	0.585506 (rank : 10)	θ value	7.34386e-10 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

ZFY16_HUMAN
NC score	0.032807 (rank : 11)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

GAB2_MOUSE
NC score	0.022294 (rank : 12)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

WISP3_HUMAN
NC score	0.021752 (rank : 13)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

RECK_HUMAN
NC score	0.020999 (rank : 14)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

DOC2G_MOUSE
NC score	0.017967 (rank : 15)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

NOV_MOUSE
NC score	0.014858 (rank : 16)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	130	Shared Neighborhood Hits	6
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

RAG1_HUMAN
NC score	0.014706 (rank : 17)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	203	Shared Neighborhood Hits	3
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

EFHC2_HUMAN
NC score	0.014340 (rank : 18)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JST6, Q5JST8, Q68DK4, Q8NEI0, Q9H653	Gene names	EFHC2
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member C2.

MKRN2_MOUSE
NC score	0.014049 (rank : 19)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

SUSD1_HUMAN
NC score	0.012260 (rank : 20)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

MASP2_HUMAN
NC score	0.011014 (rank : 21)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	364	Shared Neighborhood Hits	6
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CNTP4_HUMAN
NC score	0.010577 (rank : 22)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	187	Shared Neighborhood Hits	5
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

PLAP_MOUSE
NC score	0.009530 (rank : 23)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

JAG1_MOUSE
NC score	0.004788 (rank : 24)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	518	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

FBN2_MOUSE
NC score	0.003536 (rank : 25)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	549	Shared Neighborhood Hits	7
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.