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Network neighborhood for query Sequence : GFRA4_MOUSE

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GFRA4_MOUSE
SwissProt Accessions	Q9JJT2, Q9JJT3, Q9JJT4, Q9JJT6, Q9JJT7, Q9JJT8	Gene names	Gfra4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GFRA4_MOUSE
θ value	8.69046e-120 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JJT2, Q9JJT3, Q9JJT4, Q9JJT6, Q9JJT7, Q9JJT8	Gene names	Gfra4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA4_HUMAN
θ value	1.41016e-61 (rank : 2)	NC score	0.979451 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q9GZZ7, Q9H191, Q9H192	Gene names	GFRA4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA2_MOUSE
θ value	4.40402e-47 (rank : 3)	NC score	0.936697 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

GFRA2_HUMAN
θ value	2.18568e-46 (rank : 4)	NC score	0.936220 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

GFRA1_HUMAN
θ value	2.04573e-44 (rank : 5)	NC score	0.935615 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	P56159, O15507, O43912	Gene names	GFRA1, GDNFRA, RETL1, TRNR1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1) (RET ligand 1).

GFRA1_MOUSE
θ value	4.55743e-44 (rank : 6)	NC score	0.934132 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P97785	Gene names	Gfra1, Gdnfra, Trnr1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1).

GFRA3_MOUSE
θ value	5.584e-34 (rank : 7)	NC score	0.911041 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA3_HUMAN
θ value	1.37539e-32 (rank : 8)	NC score	0.908121 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRAL_HUMAN
θ value	3.89403e-11 (rank : 9)	NC score	0.638976 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UXV0, Q5VTF6	Gene names	GFRAL
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GFRAL_MOUSE
θ value	6.21693e-09 (rank : 10)	NC score	0.616510 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

LAMB2_HUMAN
θ value	0.0431538 (rank : 11)	NC score	0.035784 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	692	Shared Neighborhood Hits	12
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	0.47712 (rank : 12)	NC score	0.033231 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	722	Shared Neighborhood Hits	11
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

NOTC3_MOUSE
θ value	1.06291 (rank : 13)	NC score	0.017250 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	975	Shared Neighborhood Hits	12
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LTBP4_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.017366 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	607	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

CJ095_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.071181 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

LAMC3_HUMAN
θ value	2.36792 (rank : 16)	NC score	0.023966 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	588	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

FBN2_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.018199 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	560	Shared Neighborhood Hits	12
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

GAS1_MOUSE
θ value	5.27518 (rank : 18)	NC score	0.053078 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q01721	Gene names	Gas1, Gas-1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

LRP1_HUMAN
θ value	5.27518 (rank : 19)	NC score	0.011604 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	617	Shared Neighborhood Hits	10
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LAMA5_MOUSE
θ value	6.88961 (rank : 20)	NC score	0.019836 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	828	Shared Neighborhood Hits	10
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NOTC3_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.015306 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	1062	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

Hits sorted by NC score

GFRA4_MOUSE
NC score	0.999962 (rank : 1)	θ value	8.69046e-120 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JJT2, Q9JJT3, Q9JJT4, Q9JJT6, Q9JJT7, Q9JJT8	Gene names	Gfra4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA4_HUMAN
NC score	0.979451 (rank : 2)	θ value	1.41016e-61 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q9GZZ7, Q9H191, Q9H192	Gene names	GFRA4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA2_MOUSE
NC score	0.936697 (rank : 3)	θ value	4.40402e-47 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

GFRA2_HUMAN
NC score	0.936220 (rank : 4)	θ value	2.18568e-46 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

GFRA1_HUMAN
NC score	0.935615 (rank : 5)	θ value	2.04573e-44 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	P56159, O15507, O43912	Gene names	GFRA1, GDNFRA, RETL1, TRNR1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1) (RET ligand 1).

GFRA1_MOUSE
NC score	0.934132 (rank : 6)	θ value	4.55743e-44 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P97785	Gene names	Gfra1, Gdnfra, Trnr1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1).

GFRA3_MOUSE
NC score	0.911041 (rank : 7)	θ value	5.584e-34 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA3_HUMAN
NC score	0.908121 (rank : 8)	θ value	1.37539e-32 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRAL_HUMAN
NC score	0.638976 (rank : 9)	θ value	3.89403e-11 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UXV0, Q5VTF6	Gene names	GFRAL
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GFRAL_MOUSE
NC score	0.616510 (rank : 10)	θ value	6.21693e-09 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

CJ095_HUMAN
NC score	0.071181 (rank : 11)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

GAS1_MOUSE
NC score	0.053078 (rank : 12)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q01721	Gene names	Gas1, Gas-1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

LAMB2_HUMAN
NC score	0.035784 (rank : 13)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	692	Shared Neighborhood Hits	12
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
NC score	0.033231 (rank : 14)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	722	Shared Neighborhood Hits	11
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMC3_HUMAN
NC score	0.023966 (rank : 15)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	588	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA5_MOUSE
NC score	0.019836 (rank : 16)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	828	Shared Neighborhood Hits	10
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

FBN2_HUMAN
NC score	0.018199 (rank : 17)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	560	Shared Neighborhood Hits	12
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

LTBP4_MOUSE
NC score	0.017366 (rank : 18)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	607	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

NOTC3_MOUSE
NC score	0.017250 (rank : 19)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	975	Shared Neighborhood Hits	12
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.015306 (rank : 20)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	1062	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LRP1_HUMAN
NC score	0.011604 (rank : 21)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	617	Shared Neighborhood Hits	10
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).