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Network neighborhood for query Sequence : GFRA4_HUMAN

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GFRA4_HUMAN
SwissProt Accessions	Q9GZZ7, Q9H191, Q9H192	Gene names	GFRA4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GFRA4_HUMAN
θ value	6.88586e-117 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9GZZ7, Q9H191, Q9H192	Gene names	GFRA4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA4_MOUSE
θ value	1.41016e-61 (rank : 2)	NC score	0.979451 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJT2, Q9JJT3, Q9JJT4, Q9JJT6, Q9JJT7, Q9JJT8	Gene names	Gfra4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA1_MOUSE
θ value	9.52487e-34 (rank : 3)	NC score	0.909297 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P97785	Gene names	Gfra1, Gdnfra, Trnr1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1).

GFRA1_HUMAN
θ value	2.12192e-33 (rank : 4)	NC score	0.910332 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	P56159, O15507, O43912	Gene names	GFRA1, GDNFRA, RETL1, TRNR1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1) (RET ligand 1).

GFRA2_MOUSE
θ value	1.79631e-32 (rank : 5)	NC score	0.907099 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

GFRA2_HUMAN
θ value	1.52067e-31 (rank : 6)	NC score	0.906132 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

GFRA3_HUMAN
θ value	1.29031e-22 (rank : 7)	NC score	0.870484 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA3_MOUSE
θ value	4.58923e-20 (rank : 8)	NC score	0.869780 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRAL_HUMAN
θ value	5.26297e-08 (rank : 9)	NC score	0.610361 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UXV0, Q5VTF6	Gene names	GFRAL
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GFRAL_MOUSE
θ value	2.21117e-06 (rank : 10)	NC score	0.584977 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

CELR1_MOUSE
θ value	3.0926 (rank : 11)	NC score	0.004719 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	617	Shared Neighborhood Hits	4
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

DLL1_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.008204 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	456	Shared Neighborhood Hits	4
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

GAS1_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.068566 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q01721	Gene names	Gas1, Gas-1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

CRNL1_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.019151 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZJ0, Q5JY64, Q8WYI5, Q9BZI9, Q9BZJ1, Q9BZJ2, Q9GZW7, Q9H8F8, Q9NQH5, Q9NYD8	Gene names	CRNKL1, CRN
Domain Architecture
Description	Crooked neck-like protein 1 (Crooked neck homolog) (hCrn).

DLL3_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.009339 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

GAS1_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.044258 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P54826	Gene names	GAS1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

MYO7A_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.008782 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
θ value	5.27518 (rank : 18)	NC score	0.008790 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

JIP3_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.009528 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	1039	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

JIP3_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.010078 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	759	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

ZFHX2_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.002777 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	1178	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

Hits sorted by NC score

GFRA4_HUMAN
NC score	0.999962 (rank : 1)	θ value	6.88586e-117 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9GZZ7, Q9H191, Q9H192	Gene names	GFRA4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA4_MOUSE
NC score	0.979451 (rank : 2)	θ value	1.41016e-61 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJT2, Q9JJT3, Q9JJT4, Q9JJT6, Q9JJT7, Q9JJT8	Gene names	Gfra4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA1_HUMAN
NC score	0.910332 (rank : 3)	θ value	2.12192e-33 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	P56159, O15507, O43912	Gene names	GFRA1, GDNFRA, RETL1, TRNR1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1) (RET ligand 1).

GFRA1_MOUSE
NC score	0.909297 (rank : 4)	θ value	9.52487e-34 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P97785	Gene names	Gfra1, Gdnfra, Trnr1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1).

GFRA2_MOUSE
NC score	0.907099 (rank : 5)	θ value	1.79631e-32 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

GFRA2_HUMAN
NC score	0.906132 (rank : 6)	θ value	1.52067e-31 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

GFRA3_HUMAN
NC score	0.870484 (rank : 7)	θ value	1.29031e-22 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA3_MOUSE
NC score	0.869780 (rank : 8)	θ value	4.58923e-20 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRAL_HUMAN
NC score	0.610361 (rank : 9)	θ value	5.26297e-08 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UXV0, Q5VTF6	Gene names	GFRAL
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GFRAL_MOUSE
NC score	0.584977 (rank : 10)	θ value	2.21117e-06 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GAS1_MOUSE
NC score	0.068566 (rank : 11)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q01721	Gene names	Gas1, Gas-1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

GAS1_HUMAN
NC score	0.044258 (rank : 12)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P54826	Gene names	GAS1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

CRNL1_HUMAN
NC score	0.019151 (rank : 13)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZJ0, Q5JY64, Q8WYI5, Q9BZI9, Q9BZJ1, Q9BZJ2, Q9GZW7, Q9H8F8, Q9NQH5, Q9NYD8	Gene names	CRNKL1, CRN
Domain Architecture
Description	Crooked neck-like protein 1 (Crooked neck homolog) (hCrn).

JIP3_MOUSE
NC score	0.010078 (rank : 14)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	759	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

JIP3_HUMAN
NC score	0.009528 (rank : 15)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	1039	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

DLL3_HUMAN
NC score	0.009339 (rank : 16)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

MYO7A_MOUSE
NC score	0.008790 (rank : 17)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_HUMAN
NC score	0.008782 (rank : 18)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

DLL1_MOUSE
NC score	0.008204 (rank : 19)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	456	Shared Neighborhood Hits	4
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

CELR1_MOUSE
NC score	0.004719 (rank : 20)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	617	Shared Neighborhood Hits	4
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

ZFHX2_HUMAN
NC score	0.002777 (rank : 21)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	1178	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.