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Network neighborhood for query Sequence : GFRA1_HUMAN

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GFRA1_HUMAN
SwissProt Accessions	P56159, O15507, O43912	Gene names	GFRA1, GDNFRA, RETL1, TRNR1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1) (RET ligand 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GFRA1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P56159, O15507, O43912	Gene names	GFRA1, GDNFRA, RETL1, TRNR1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1) (RET ligand 1).

GFRA1_MOUSE
θ value	0 (rank : 2)	NC score	0.997753 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P97785	Gene names	Gfra1, Gdnfra, Trnr1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1).

GFRA2_MOUSE
θ value	2.89301e-115 (rank : 3)	NC score	0.975624 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

GFRA2_HUMAN
θ value	3.77839e-115 (rank : 4)	NC score	0.975868 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

GFRA3_MOUSE
θ value	2.75849e-49 (rank : 5)	NC score	0.914373 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA3_HUMAN
θ value	1.04822e-48 (rank : 6)	NC score	0.909867 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA4_MOUSE
θ value	2.04573e-44 (rank : 7)	NC score	0.935615 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJT2, Q9JJT3, Q9JJT4, Q9JJT6, Q9JJT7, Q9JJT8	Gene names	Gfra4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA4_HUMAN
θ value	2.12192e-33 (rank : 8)	NC score	0.910332 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZZ7, Q9H191, Q9H192	Gene names	GFRA4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRAL_HUMAN
θ value	1.86753e-13 (rank : 9)	NC score	0.626376 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UXV0, Q5VTF6	Gene names	GFRAL
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GFRAL_MOUSE
θ value	1.58096e-12 (rank : 10)	NC score	0.607250 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GAK10_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.035293 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	289	Shared Neighborhood Hits	9
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.034271 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	409	Shared Neighborhood Hits	9
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.034657 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	374	Shared Neighborhood Hits	9
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK1_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.035122 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	268	Shared Neighborhood Hits	9
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.034308 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	406	Shared Neighborhood Hits	9
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK3_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.035522 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	182	Shared Neighborhood Hits	9
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.034293 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	415	Shared Neighborhood Hits	9
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.034193 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	429	Shared Neighborhood Hits	9
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

RYR3_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.012669 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

NUPL2_MOUSE
θ value	6.88961 (rank : 20)	NC score	0.013926 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIC2, Q8BJX3, Q8BVP7, Q924S0	Gene names	Nupl2
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1).

WIPI2_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.007127 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4P8, Q5MNZ8, Q6FI96, Q75L50, Q96IE4, Q9Y364	Gene names	WIPI2
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2).

Hits sorted by NC score

GFRA1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P56159, O15507, O43912	Gene names	GFRA1, GDNFRA, RETL1, TRNR1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1) (RET ligand 1).

GFRA1_MOUSE
NC score	0.997753 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P97785	Gene names	Gfra1, Gdnfra, Trnr1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1).

GFRA2_HUMAN
NC score	0.975868 (rank : 3)	θ value	3.77839e-115 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

GFRA2_MOUSE
NC score	0.975624 (rank : 4)	θ value	2.89301e-115 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

GFRA4_MOUSE
NC score	0.935615 (rank : 5)	θ value	2.04573e-44 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJT2, Q9JJT3, Q9JJT4, Q9JJT6, Q9JJT7, Q9JJT8	Gene names	Gfra4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA3_MOUSE
NC score	0.914373 (rank : 6)	θ value	2.75849e-49 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA4_HUMAN
NC score	0.910332 (rank : 7)	θ value	2.12192e-33 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZZ7, Q9H191, Q9H192	Gene names	GFRA4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA3_HUMAN
NC score	0.909867 (rank : 8)	θ value	1.04822e-48 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRAL_HUMAN
NC score	0.626376 (rank : 9)	θ value	1.86753e-13 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UXV0, Q5VTF6	Gene names	GFRAL
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GFRAL_MOUSE
NC score	0.607250 (rank : 10)	θ value	1.58096e-12 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GAK3_HUMAN
NC score	0.035522 (rank : 11)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	182	Shared Neighborhood Hits	9
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK10_HUMAN
NC score	0.035293 (rank : 12)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	289	Shared Neighborhood Hits	9
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK1_HUMAN
NC score	0.035122 (rank : 13)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	268	Shared Neighborhood Hits	9
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
NC score	0.034657 (rank : 14)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	374	Shared Neighborhood Hits	9
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.034308 (rank : 15)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	406	Shared Neighborhood Hits	9
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
NC score	0.034293 (rank : 16)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	415	Shared Neighborhood Hits	9
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.034271 (rank : 17)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	409	Shared Neighborhood Hits	9
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
NC score	0.034193 (rank : 18)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	429	Shared Neighborhood Hits	9
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

NUPL2_MOUSE
NC score	0.013926 (rank : 19)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIC2, Q8BJX3, Q8BVP7, Q924S0	Gene names	Nupl2
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1).

RYR3_HUMAN
NC score	0.012669 (rank : 20)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

WIPI2_HUMAN
NC score	0.007127 (rank : 21)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4P8, Q5MNZ8, Q6FI96, Q75L50, Q96IE4, Q9Y364	Gene names	WIPI2
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2).