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Network neighborhood for query Sequence : GFRA3_MOUSE

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GFRA3_MOUSE
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GFRA3_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA3_HUMAN
θ value	6.77497e-173 (rank : 2)	NC score	0.995293 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA2_HUMAN
θ value	1.36585e-56 (rank : 3)	NC score	0.922121 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

GFRA2_MOUSE
θ value	1.36585e-56 (rank : 4)	NC score	0.921732 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

GFRA1_HUMAN
θ value	2.75849e-49 (rank : 5)	NC score	0.914373 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	P56159, O15507, O43912	Gene names	GFRA1, GDNFRA, RETL1, TRNR1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1) (RET ligand 1).

GFRA1_MOUSE
θ value	1.36902e-48 (rank : 6)	NC score	0.911958 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P97785	Gene names	Gfra1, Gdnfra, Trnr1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1).

GFRA4_MOUSE
θ value	5.584e-34 (rank : 7)	NC score	0.911041 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JJT2, Q9JJT3, Q9JJT4, Q9JJT6, Q9JJT7, Q9JJT8	Gene names	Gfra4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA4_HUMAN
θ value	4.58923e-20 (rank : 8)	NC score	0.869780 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZZ7, Q9H191, Q9H192	Gene names	GFRA4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRAL_MOUSE
θ value	1.86753e-13 (rank : 9)	NC score	0.627737 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GFRAL_HUMAN
θ value	4.59992e-12 (rank : 10)	NC score	0.636095 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UXV0, Q5VTF6	Gene names	GFRAL
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

NOTC4_HUMAN
θ value	0.47712 (rank : 11)	NC score	0.011870 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	905	Shared Neighborhood Hits	6
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

FBN2_HUMAN
θ value	0.62314 (rank : 12)	NC score	0.015430 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	560	Shared Neighborhood Hits	8
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

DNER_MOUSE
θ value	1.38821 (rank : 13)	NC score	0.014153 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	413	Shared Neighborhood Hits	6
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

CJ095_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.063578 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

K0408_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.021357 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZU52, O43158, Q5TF20, Q7L2M2	Gene names	KIAA0408
Domain Architecture	No domain graphic available
Description	Protein KIAA0408.

AGRIN_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.018454 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	582	Shared Neighborhood Hits	8
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

DHB2_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.010754 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	P51658, O08898	Gene names	Hsd17b2, Edh17b2
Domain Architecture
Description	Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-HSD 2) (17- beta-hydroxysteroid dehydrogenase 2).

DLL1_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.009703 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	455	Shared Neighborhood Hits	6
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

SMYD5_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.010928 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q6GMV2, Q13558	Gene names	SMYD5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

Hits sorted by NC score

GFRA3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA3_HUMAN
NC score	0.995293 (rank : 2)	θ value	6.77497e-173 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GFRA2_HUMAN
NC score	0.922121 (rank : 3)	θ value	1.36585e-56 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	O00451, O15316, O15328, Q7Z5C2	Gene names	GFRA2, GDNFRB, RETL2, TRNR2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta) (RET ligand 2).

GFRA2_MOUSE
NC score	0.921732 (rank : 4)	θ value	1.36585e-56 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	O08842	Gene names	Gfra2, Gdnfrb, Trnr2
Domain Architecture
Description	GDNF family receptor alpha-2 precursor (GFR-alpha-2) (Neurturin receptor alpha) (NTNR-alpha) (NRTNR-alpha) (TGF-beta-related neurotrophic factor receptor 2) (GDNF receptor beta) (GDNFR-beta).

GFRA1_HUMAN
NC score	0.914373 (rank : 5)	θ value	2.75849e-49 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	P56159, O15507, O43912	Gene names	GFRA1, GDNFRA, RETL1, TRNR1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1) (RET ligand 1).

GFRA1_MOUSE
NC score	0.911958 (rank : 6)	θ value	1.36902e-48 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P97785	Gene names	Gfra1, Gdnfra, Trnr1
Domain Architecture
Description	GDNF family receptor alpha-1 precursor (GFR-alpha-1) (GDNF receptor alpha) (GDNFR-alpha) (TGF-beta-related neurotrophic factor receptor 1).

GFRA4_MOUSE
NC score	0.911041 (rank : 7)	θ value	5.584e-34 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JJT2, Q9JJT3, Q9JJT4, Q9JJT6, Q9JJT7, Q9JJT8	Gene names	Gfra4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRA4_HUMAN
NC score	0.869780 (rank : 8)	θ value	4.58923e-20 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZZ7, Q9H191, Q9H192	Gene names	GFRA4
Domain Architecture
Description	GDNF family receptor alpha-4 precursor (GFR-alpha-4) (Persephin receptor).

GFRAL_HUMAN
NC score	0.636095 (rank : 9)	θ value	4.59992e-12 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UXV0, Q5VTF6	Gene names	GFRAL
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

GFRAL_MOUSE
NC score	0.627737 (rank : 10)	θ value	1.86753e-13 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q6SJE0, Q6SJD9	Gene names	Gfral, Gral
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-like precursor.

CJ095_HUMAN
NC score	0.063578 (rank : 11)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

K0408_HUMAN
NC score	0.021357 (rank : 12)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZU52, O43158, Q5TF20, Q7L2M2	Gene names	KIAA0408
Domain Architecture	No domain graphic available
Description	Protein KIAA0408.

AGRIN_HUMAN
NC score	0.018454 (rank : 13)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	582	Shared Neighborhood Hits	8
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

FBN2_HUMAN
NC score	0.015430 (rank : 14)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	560	Shared Neighborhood Hits	8
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

DNER_MOUSE
NC score	0.014153 (rank : 15)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	413	Shared Neighborhood Hits	6
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

NOTC4_HUMAN
NC score	0.011870 (rank : 16)	θ value	0.47712 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	905	Shared Neighborhood Hits	6
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

SMYD5_HUMAN
NC score	0.010928 (rank : 17)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q6GMV2, Q13558	Gene names	SMYD5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

DHB2_MOUSE
NC score	0.010754 (rank : 18)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	P51658, O08898	Gene names	Hsd17b2, Edh17b2
Domain Architecture
Description	Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-HSD 2) (17- beta-hydroxysteroid dehydrogenase 2).

DLL1_HUMAN
NC score	0.009703 (rank : 19)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	455	Shared Neighborhood Hits	6
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).