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Network neighborhood for query Sequence : AGRIN_HUMAN

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AGRIN_HUMAN
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AGRIN_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	582	Target Neighborhood Hits	582	Shared Neighborhood Hits	582
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

PGBM_HUMAN
θ value	3.22093e-90 (rank : 2)	NC score	0.579733 (rank : 89)
Query Neighborhood Hits	582	Target Neighborhood Hits	1113	Shared Neighborhood Hits	373
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	1.59853e-89 (rank : 3)	NC score	0.593151 (rank : 78)
Query Neighborhood Hits	582	Target Neighborhood Hits	1073	Shared Neighborhood Hits	364
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NRX2A_HUMAN
θ value	2.76489e-41 (rank : 4)	NC score	0.514032 (rank : 132)
Query Neighborhood Hits	582	Target Neighborhood Hits	614	Shared Neighborhood Hits	168
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	7.04741e-37 (rank : 5)	NC score	0.545615 (rank : 115)
Query Neighborhood Hits	582	Target Neighborhood Hits	164	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

NRX1A_HUMAN
θ value	2.34606e-32 (rank : 6)	NC score	0.551171 (rank : 110)
Query Neighborhood Hits	582	Target Neighborhood Hits	170	Shared Neighborhood Hits	137
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

SLIT1_HUMAN
θ value	4.00176e-32 (rank : 7)	NC score	0.581069 (rank : 86)
Query Neighborhood Hits	582	Target Neighborhood Hits	700	Shared Neighborhood Hits	344
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

FATH_HUMAN
θ value	8.91499e-32 (rank : 8)	NC score	0.427509 (rank : 208)
Query Neighborhood Hits	582	Target Neighborhood Hits	570	Shared Neighborhood Hits	303
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

NRX1A_MOUSE
θ value	3.3877e-31 (rank : 9)	NC score	0.548741 (rank : 113)
Query Neighborhood Hits	582	Target Neighborhood Hits	164	Shared Neighborhood Hits	136
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

SLIT1_MOUSE
θ value	6.38894e-30 (rank : 10)	NC score	0.579646 (rank : 90)
Query Neighborhood Hits	582	Target Neighborhood Hits	715	Shared Neighborhood Hits	347
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

FST_MOUSE
θ value	4.57862e-28 (rank : 11)	NC score	0.412880 (rank : 226)
Query Neighborhood Hits	582	Target Neighborhood Hits	146	Shared Neighborhood Hits	136
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_HUMAN
θ value	1.02001e-27 (rank : 12)	NC score	0.401976 (rank : 234)
Query Neighborhood Hits	582	Target Neighborhood Hits	129	Shared Neighborhood Hits	118
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

SLIT2_HUMAN
θ value	1.33217e-27 (rank : 13)	NC score	0.574943 (rank : 92)
Query Neighborhood Hits	582	Target Neighborhood Hits	708	Shared Neighborhood Hits	346
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

MEGF6_HUMAN
θ value	2.27234e-27 (rank : 14)	NC score	0.718347 (rank : 30)
Query Neighborhood Hits	582	Target Neighborhood Hits	671	Shared Neighborhood Hits	402
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NOTC3_HUMAN
θ value	2.27234e-27 (rank : 15)	NC score	0.670467 (rank : 48)
Query Neighborhood Hits	582	Target Neighborhood Hits	1062	Shared Neighborhood Hits	405
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LAMB2_MOUSE
θ value	1.12775e-26 (rank : 16)	NC score	0.720570 (rank : 27)
Query Neighborhood Hits	582	Target Neighborhood Hits	722	Shared Neighborhood Hits	308
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

CELR2_HUMAN
θ value	4.28545e-26 (rank : 17)	NC score	0.442760 (rank : 197)
Query Neighborhood Hits	582	Target Neighborhood Hits	657	Shared Neighborhood Hits	320
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

LAMC3_MOUSE
θ value	7.30988e-26 (rank : 18)	NC score	0.728400 (rank : 16)
Query Neighborhood Hits	582	Target Neighborhood Hits	624	Shared Neighborhood Hits	298
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

CELR3_MOUSE
θ value	2.12685e-25 (rank : 19)	NC score	0.442761 (rank : 196)
Query Neighborhood Hits	582	Target Neighborhood Hits	687	Shared Neighborhood Hits	331
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

SLIT2_MOUSE
θ value	2.12685e-25 (rank : 20)	NC score	0.566705 (rank : 100)
Query Neighborhood Hits	582	Target Neighborhood Hits	684	Shared Neighborhood Hits	332
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

NOTC1_HUMAN
θ value	3.62785e-25 (rank : 21)	NC score	0.673972 (rank : 43)
Query Neighborhood Hits	582	Target Neighborhood Hits	906	Shared Neighborhood Hits	390
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CELR3_HUMAN
θ value	4.73814e-25 (rank : 22)	NC score	0.444286 (rank : 194)
Query Neighborhood Hits	582	Target Neighborhood Hits	680	Shared Neighborhood Hits	328
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

NOTC1_MOUSE
θ value	4.73814e-25 (rank : 23)	NC score	0.691550 (rank : 38)
Query Neighborhood Hits	582	Target Neighborhood Hits	916	Shared Neighborhood Hits	388
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LAMA1_HUMAN
θ value	6.84181e-24 (rank : 24)	NC score	0.749386 (rank : 7)
Query Neighborhood Hits	582	Target Neighborhood Hits	804	Shared Neighborhood Hits	315
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NOTC3_MOUSE
θ value	6.84181e-24 (rank : 25)	NC score	0.671187 (rank : 47)
Query Neighborhood Hits	582	Target Neighborhood Hits	975	Shared Neighborhood Hits	406
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CRUM1_HUMAN
θ value	8.93572e-24 (rank : 26)	NC score	0.756041 (rank : 3)
Query Neighborhood Hits	582	Target Neighborhood Hits	457	Shared Neighborhood Hits	345
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

LAMB1_MOUSE
θ value	1.16704e-23 (rank : 27)	NC score	0.676172 (rank : 42)
Query Neighborhood Hits	582	Target Neighborhood Hits	919	Shared Neighborhood Hits	282
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMA5_MOUSE
θ value	2.59989e-23 (rank : 28)	NC score	0.758713 (rank : 2)
Query Neighborhood Hits	582	Target Neighborhood Hits	828	Shared Neighborhood Hits	346
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_HUMAN
θ value	2.59989e-23 (rank : 29)	NC score	0.720028 (rank : 28)
Query Neighborhood Hits	582	Target Neighborhood Hits	692	Shared Neighborhood Hits	298
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

NOTC2_HUMAN
θ value	3.39556e-23 (rank : 30)	NC score	0.657185 (rank : 53)
Query Neighborhood Hits	582	Target Neighborhood Hits	1113	Shared Neighborhood Hits	408
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TEFF2_HUMAN
θ value	4.43474e-23 (rank : 31)	NC score	0.472503 (rank : 164)
Query Neighborhood Hits	582	Target Neighborhood Hits	211	Shared Neighborhood Hits	182
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	4.43474e-23 (rank : 32)	NC score	0.475939 (rank : 160)
Query Neighborhood Hits	582	Target Neighborhood Hits	214	Shared Neighborhood Hits	185
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

LAMB1_HUMAN
θ value	5.79196e-23 (rank : 33)	NC score	0.653044 (rank : 59)
Query Neighborhood Hits	582	Target Neighborhood Hits	1018	Shared Neighborhood Hits	294
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMA1_MOUSE
θ value	1.29031e-22 (rank : 34)	NC score	0.750937 (rank : 6)
Query Neighborhood Hits	582	Target Neighborhood Hits	838	Shared Neighborhood Hits	327
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC3_HUMAN
θ value	1.6852e-22 (rank : 35)	NC score	0.726150 (rank : 20)
Query Neighborhood Hits	582	Target Neighborhood Hits	588	Shared Neighborhood Hits	302
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA5_HUMAN
θ value	3.75424e-22 (rank : 36)	NC score	0.744610 (rank : 8)
Query Neighborhood Hits	582	Target Neighborhood Hits	976	Shared Neighborhood Hits	354
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NOTC4_HUMAN
θ value	2.43343e-21 (rank : 37)	NC score	0.655592 (rank : 57)
Query Neighborhood Hits	582	Target Neighborhood Hits	905	Shared Neighborhood Hits	400
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

CELR2_MOUSE
θ value	3.17815e-21 (rank : 38)	NC score	0.416168 (rank : 225)
Query Neighborhood Hits	582	Target Neighborhood Hits	584	Shared Neighborhood Hits	292
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

LAMC1_HUMAN
θ value	5.42112e-21 (rank : 39)	NC score	0.655768 (rank : 55)
Query Neighborhood Hits	582	Target Neighborhood Hits	922	Shared Neighborhood Hits	294
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SLIT3_MOUSE
θ value	7.0802e-21 (rank : 40)	NC score	0.558931 (rank : 104)
Query Neighborhood Hits	582	Target Neighborhood Hits	700	Shared Neighborhood Hits	340
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SLIT3_HUMAN
θ value	1.2077e-20 (rank : 41)	NC score	0.548471 (rank : 114)
Query Neighborhood Hits	582	Target Neighborhood Hits	682	Shared Neighborhood Hits	322
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

CRUM1_MOUSE
θ value	1.5773e-20 (rank : 42)	NC score	0.755295 (rank : 4)
Query Neighborhood Hits	582	Target Neighborhood Hits	444	Shared Neighborhood Hits	342
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

NOTC2_MOUSE
θ value	1.5773e-20 (rank : 43)	NC score	0.661135 (rank : 52)
Query Neighborhood Hits	582	Target Neighborhood Hits	1069	Shared Neighborhood Hits	400
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

LAMA2_HUMAN
θ value	3.51386e-20 (rank : 44)	NC score	0.696356 (rank : 35)
Query Neighborhood Hits	582	Target Neighborhood Hits	1092	Shared Neighborhood Hits	321
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NOTC4_MOUSE
θ value	5.99374e-20 (rank : 45)	NC score	0.655624 (rank : 56)
Query Neighborhood Hits	582	Target Neighborhood Hits	872	Shared Neighborhood Hits	393
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

LAMC1_MOUSE
θ value	7.82807e-20 (rank : 46)	NC score	0.672795 (rank : 44)
Query Neighborhood Hits	582	Target Neighborhood Hits	856	Shared Neighborhood Hits	290
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

USH2A_MOUSE
θ value	1.33526e-19 (rank : 47)	NC score	0.648445 (rank : 61)
Query Neighborhood Hits	582	Target Neighborhood Hits	626	Shared Neighborhood Hits	294
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

USH2A_HUMAN
θ value	5.07402e-19 (rank : 48)	NC score	0.634670 (rank : 65)
Query Neighborhood Hits	582	Target Neighborhood Hits	600	Shared Neighborhood Hits	271
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LAMA2_MOUSE
θ value	8.65492e-19 (rank : 49)	NC score	0.669099 (rank : 50)
Query Neighborhood Hits	582	Target Neighborhood Hits	1198	Shared Neighborhood Hits	328
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB3_HUMAN
θ value	1.13037e-18 (rank : 50)	NC score	0.677168 (rank : 41)
Query Neighborhood Hits	582	Target Neighborhood Hits	461	Shared Neighborhood Hits	215
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

CRUM2_HUMAN
θ value	3.28887e-18 (rank : 51)	NC score	0.743997 (rank : 9)
Query Neighborhood Hits	582	Target Neighborhood Hits	453	Shared Neighborhood Hits	341
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CELR1_HUMAN
θ value	4.29542e-18 (rank : 52)	NC score	0.421256 (rank : 211)
Query Neighborhood Hits	582	Target Neighborhood Hits	613	Shared Neighborhood Hits	296
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CNTP4_MOUSE
θ value	1.24977e-17 (rank : 53)	NC score	0.459232 (rank : 173)
Query Neighborhood Hits	582	Target Neighborhood Hits	193	Shared Neighborhood Hits	141
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

MEGF9_HUMAN
θ value	4.74913e-17 (rank : 54)	NC score	0.735318 (rank : 12)
Query Neighborhood Hits	582	Target Neighborhood Hits	557	Shared Neighborhood Hits	300
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CELR1_MOUSE
θ value	1.38178e-16 (rank : 55)	NC score	0.418449 (rank : 218)
Query Neighborhood Hits	582	Target Neighborhood Hits	617	Shared Neighborhood Hits	301
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

LAMC2_HUMAN
θ value	2.35696e-16 (rank : 56)	NC score	0.672205 (rank : 45)
Query Neighborhood Hits	582	Target Neighborhood Hits	715	Shared Neighborhood Hits	275
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

SREC_HUMAN
θ value	2.35696e-16 (rank : 57)	NC score	0.752589 (rank : 5)
Query Neighborhood Hits	582	Target Neighborhood Hits	645	Shared Neighborhood Hits	372
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

MEGF9_MOUSE
θ value	3.07829e-16 (rank : 58)	NC score	0.699121 (rank : 34)
Query Neighborhood Hits	582	Target Neighborhood Hits	896	Shared Neighborhood Hits	283
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMB3_MOUSE
θ value	5.25075e-16 (rank : 59)	NC score	0.693846 (rank : 37)
Query Neighborhood Hits	582	Target Neighborhood Hits	444	Shared Neighborhood Hits	237
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC2_MOUSE
θ value	6.85773e-16 (rank : 60)	NC score	0.695104 (rank : 36)
Query Neighborhood Hits	582	Target Neighborhood Hits	614	Shared Neighborhood Hits	276
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

CNTP4_HUMAN
θ value	1.52774e-15 (rank : 61)	NC score	0.455163 (rank : 182)
Query Neighborhood Hits	582	Target Neighborhood Hits	187	Shared Neighborhood Hits	126
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

JAG2_HUMAN
θ value	1.99529e-15 (rank : 62)	NC score	0.726963 (rank : 19)
Query Neighborhood Hits	582	Target Neighborhood Hits	491	Shared Neighborhood Hits	364
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

CNTP2_HUMAN
θ value	5.8054e-15 (rank : 63)	NC score	0.455897 (rank : 181)
Query Neighborhood Hits	582	Target Neighborhood Hits	199	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

FSTL3_HUMAN
θ value	7.58209e-15 (rank : 64)	NC score	0.427513 (rank : 207)
Query Neighborhood Hits	582	Target Neighborhood Hits	162	Shared Neighborhood Hits	142
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

LAMA3_MOUSE
θ value	7.58209e-15 (rank : 65)	NC score	0.682694 (rank : 39)
Query Neighborhood Hits	582	Target Neighborhood Hits	859	Shared Neighborhood Hits	321
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

CNTP3_HUMAN
θ value	1.29331e-14 (rank : 66)	NC score	0.444403 (rank : 193)
Query Neighborhood Hits	582	Target Neighborhood Hits	195	Shared Neighborhood Hits	133
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

FAT2_HUMAN
θ value	1.68911e-14 (rank : 67)	NC score	0.310730 (rank : 280)
Query Neighborhood Hits	582	Target Neighborhood Hits	507	Shared Neighborhood Hits	233
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FSTL3_MOUSE
θ value	4.91457e-14 (rank : 68)	NC score	0.410318 (rank : 227)
Query Neighborhood Hits	582	Target Neighborhood Hits	152	Shared Neighborhood Hits	139
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

JAG2_MOUSE
θ value	4.91457e-14 (rank : 69)	NC score	0.725135 (rank : 21)
Query Neighborhood Hits	582	Target Neighborhood Hits	504	Shared Neighborhood Hits	365
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

SREC2_MOUSE
θ value	8.38298e-14 (rank : 70)	NC score	0.742354 (rank : 10)
Query Neighborhood Hits	582	Target Neighborhood Hits	605	Shared Neighborhood Hits	360
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

FBN3_HUMAN
θ value	1.42992e-13 (rank : 71)	NC score	0.591855 (rank : 79)
Query Neighborhood Hits	582	Target Neighborhood Hits	543	Shared Neighborhood Hits	368
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

SREC2_HUMAN
θ value	1.42992e-13 (rank : 72)	NC score	0.737630 (rank : 11)
Query Neighborhood Hits	582	Target Neighborhood Hits	645	Shared Neighborhood Hits	359
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

CNTP2_MOUSE
θ value	4.16044e-13 (rank : 73)	NC score	0.456712 (rank : 179)
Query Neighborhood Hits	582	Target Neighborhood Hits	194	Shared Neighborhood Hits	143
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

DLL1_MOUSE
θ value	4.16044e-13 (rank : 74)	NC score	0.729220 (rank : 13)
Query Neighborhood Hits	582	Target Neighborhood Hits	456	Shared Neighborhood Hits	351
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

ISK5_HUMAN
θ value	4.16044e-13 (rank : 75)	NC score	0.216150 (rank : 337)
Query Neighborhood Hits	582	Target Neighborhood Hits	89	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

NTNG1_HUMAN
θ value	5.43371e-13 (rank : 76)	NC score	0.656055 (rank : 54)
Query Neighborhood Hits	582	Target Neighborhood Hits	247	Shared Neighborhood Hits	206
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	9.26847e-13 (rank : 77)	NC score	0.669517 (rank : 49)
Query Neighborhood Hits	582	Target Neighborhood Hits	276	Shared Neighborhood Hits	233
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

JAG1_HUMAN
θ value	1.58096e-12 (rank : 78)	NC score	0.728291 (rank : 17)
Query Neighborhood Hits	582	Target Neighborhood Hits	514	Shared Neighborhood Hits	373
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

LTBP4_MOUSE
θ value	1.58096e-12 (rank : 79)	NC score	0.599606 (rank : 75)
Query Neighborhood Hits	582	Target Neighborhood Hits	607	Shared Neighborhood Hits	346
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

NTNG1_MOUSE
θ value	1.58096e-12 (rank : 80)	NC score	0.654379 (rank : 58)
Query Neighborhood Hits	582	Target Neighborhood Hits	246	Shared Neighborhood Hits	206
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LAMA4_MOUSE
θ value	3.52202e-12 (rank : 81)	NC score	0.624516 (rank : 68)
Query Neighborhood Hits	582	Target Neighborhood Hits	584	Shared Neighborhood Hits	219
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_HUMAN
θ value	4.59992e-12 (rank : 82)	NC score	0.595024 (rank : 77)
Query Neighborhood Hits	582	Target Neighborhood Hits	708	Shared Neighborhood Hits	222
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

NET2_MOUSE
θ value	4.59992e-12 (rank : 83)	NC score	0.602835 (rank : 73)
Query Neighborhood Hits	582	Target Neighborhood Hits	193	Shared Neighborhood Hits	163
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

JAG1_MOUSE
θ value	6.00763e-12 (rank : 84)	NC score	0.728971 (rank : 14)
Query Neighborhood Hits	582	Target Neighborhood Hits	518	Shared Neighborhood Hits	375
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

NET1_MOUSE
θ value	6.00763e-12 (rank : 85)	NC score	0.568021 (rank : 97)
Query Neighborhood Hits	582	Target Neighborhood Hits	151	Shared Neighborhood Hits	120
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

DLL1_HUMAN
θ value	7.84624e-12 (rank : 86)	NC score	0.728568 (rank : 15)
Query Neighborhood Hits	582	Target Neighborhood Hits	455	Shared Neighborhood Hits	348
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

LTBP2_HUMAN
θ value	1.02475e-11 (rank : 87)	NC score	0.580187 (rank : 88)
Query Neighborhood Hits	582	Target Neighborhood Hits	552	Shared Neighborhood Hits	351
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NET2_HUMAN
θ value	1.33837e-11 (rank : 88)	NC score	0.598363 (rank : 76)
Query Neighborhood Hits	582	Target Neighborhood Hits	194	Shared Neighborhood Hits	158
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET1_HUMAN
θ value	1.74796e-11 (rank : 89)	NC score	0.570792 (rank : 93)
Query Neighborhood Hits	582	Target Neighborhood Hits	149	Shared Neighborhood Hits	121
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

KR104_HUMAN
θ value	2.28291e-11 (rank : 90)	NC score	0.549588 (rank : 111)
Query Neighborhood Hits	582	Target Neighborhood Hits	313	Shared Neighborhood Hits	232
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

NET4_MOUSE
θ value	2.28291e-11 (rank : 91)	NC score	0.600218 (rank : 74)
Query Neighborhood Hits	582	Target Neighborhood Hits	180	Shared Neighborhood Hits	158
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

FSTL4_MOUSE
θ value	2.98157e-11 (rank : 92)	NC score	0.161998 (rank : 417)
Query Neighborhood Hits	582	Target Neighborhood Hits	333	Shared Neighborhood Hits	64
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

NET4_HUMAN
θ value	2.98157e-11 (rank : 93)	NC score	0.603947 (rank : 72)
Query Neighborhood Hits	582	Target Neighborhood Hits	191	Shared Neighborhood Hits	158
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

TENX_HUMAN
θ value	2.98157e-11 (rank : 94)	NC score	0.559370 (rank : 103)
Query Neighborhood Hits	582	Target Neighborhood Hits	789	Shared Neighborhood Hits	360
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

FRAS1_MOUSE
θ value	8.67504e-11 (rank : 95)	NC score	0.418809 (rank : 216)
Query Neighborhood Hits	582	Target Neighborhood Hits	747	Shared Neighborhood Hits	292
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

STAB2_HUMAN
θ value	8.67504e-11 (rank : 96)	NC score	0.634767 (rank : 64)
Query Neighborhood Hits	582	Target Neighborhood Hits	534	Shared Neighborhood Hits	360
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

FRAS1_HUMAN
θ value	1.9326e-10 (rank : 97)	NC score	0.430469 (rank : 204)
Query Neighborhood Hits	582	Target Neighborhood Hits	759	Shared Neighborhood Hits	303
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

TENA_MOUSE
θ value	1.9326e-10 (rank : 98)	NC score	0.551840 (rank : 108)
Query Neighborhood Hits	582	Target Neighborhood Hits	596	Shared Neighborhood Hits	333
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

DLL4_MOUSE
θ value	3.29651e-10 (rank : 99)	NC score	0.728120 (rank : 18)
Query Neighborhood Hits	582	Target Neighborhood Hits	440	Shared Neighborhood Hits	344
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

EDIL3_MOUSE
θ value	3.29651e-10 (rank : 100)	NC score	0.583629 (rank : 85)
Query Neighborhood Hits	582	Target Neighborhood Hits	317	Shared Neighborhood Hits	266
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

NTNG2_MOUSE
θ value	3.29651e-10 (rank : 101)	NC score	0.667250 (rank : 51)
Query Neighborhood Hits	582	Target Neighborhood Hits	276	Shared Neighborhood Hits	237
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

EDIL3_HUMAN
θ value	5.62301e-10 (rank : 102)	NC score	0.562635 (rank : 101)
Query Neighborhood Hits	582	Target Neighborhood Hits	292	Shared Neighborhood Hits	245
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LTBP2_MOUSE
θ value	5.62301e-10 (rank : 103)	NC score	0.578275 (rank : 91)
Query Neighborhood Hits	582	Target Neighborhood Hits	617	Shared Neighborhood Hits	346
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

RECK_HUMAN
θ value	5.62301e-10 (rank : 104)	NC score	0.310304 (rank : 281)
Query Neighborhood Hits	582	Target Neighborhood Hits	189	Shared Neighborhood Hits	157
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

FSTL4_HUMAN
θ value	9.59137e-10 (rank : 105)	NC score	0.158479 (rank : 425)
Query Neighborhood Hits	582	Target Neighborhood Hits	344	Shared Neighborhood Hits	62
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

DLL4_HUMAN
θ value	2.13673e-09 (rank : 106)	NC score	0.723646 (rank : 23)
Query Neighborhood Hits	582	Target Neighborhood Hits	435	Shared Neighborhood Hits	336
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

FSTL1_HUMAN
θ value	2.13673e-09 (rank : 107)	NC score	0.277090 (rank : 298)
Query Neighborhood Hits	582	Target Neighborhood Hits	68	Shared Neighborhood Hits	61
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
θ value	2.13673e-09 (rank : 108)	NC score	0.274385 (rank : 301)
Query Neighborhood Hits	582	Target Neighborhood Hits	74	Shared Neighborhood Hits	60
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

RECK_MOUSE
θ value	2.79066e-09 (rank : 109)	NC score	0.275512 (rank : 299)
Query Neighborhood Hits	582	Target Neighborhood Hits	158	Shared Neighborhood Hits	134
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

ZAN_MOUSE
θ value	3.64472e-09 (rank : 110)	NC score	0.540253 (rank : 118)
Query Neighborhood Hits	582	Target Neighborhood Hits	808	Shared Neighborhood Hits	384
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

DLL3_MOUSE
θ value	6.21693e-09 (rank : 111)	NC score	0.713453 (rank : 31)
Query Neighborhood Hits	582	Target Neighborhood Hits	399	Shared Neighborhood Hits	323
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLK_MOUSE
θ value	8.11959e-09 (rank : 112)	NC score	0.720003 (rank : 29)
Query Neighborhood Hits	582	Target Neighborhood Hits	374	Shared Neighborhood Hits	320
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

FBN2_MOUSE
θ value	8.11959e-09 (rank : 113)	NC score	0.585356 (rank : 82)
Query Neighborhood Hits	582	Target Neighborhood Hits	549	Shared Neighborhood Hits	371
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

MEGF8_MOUSE
θ value	1.80886e-08 (rank : 114)	NC score	0.640885 (rank : 62)
Query Neighborhood Hits	582	Target Neighborhood Hits	520	Shared Neighborhood Hits	308
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

FBN1_HUMAN
θ value	4.0297e-08 (rank : 115)	NC score	0.584567 (rank : 84)
Query Neighborhood Hits	582	Target Neighborhood Hits	557	Shared Neighborhood Hits	370
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP3_HUMAN
θ value	4.0297e-08 (rank : 116)	NC score	0.558614 (rank : 105)
Query Neighborhood Hits	582	Target Neighborhood Hits	502	Shared Neighborhood Hits	330
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MEGF8_HUMAN
θ value	4.0297e-08 (rank : 117)	NC score	0.651602 (rank : 60)
Query Neighborhood Hits	582	Target Neighborhood Hits	528	Shared Neighborhood Hits	314
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

FSTL5_HUMAN
θ value	6.87365e-08 (rank : 118)	NC score	0.145853 (rank : 444)
Query Neighborhood Hits	582	Target Neighborhood Hits	347	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

TENA_HUMAN
θ value	6.87365e-08 (rank : 119)	NC score	0.555373 (rank : 106)
Query Neighborhood Hits	582	Target Neighborhood Hits	631	Shared Neighborhood Hits	342
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

DLL3_HUMAN
θ value	8.97725e-08 (rank : 120)	NC score	0.722834 (rank : 24)
Query Neighborhood Hits	582	Target Neighborhood Hits	419	Shared Neighborhood Hits	334
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

FBN2_HUMAN
θ value	8.97725e-08 (rank : 121)	NC score	0.586006 (rank : 81)
Query Neighborhood Hits	582	Target Neighborhood Hits	560	Shared Neighborhood Hits	375
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

DLK_HUMAN
θ value	1.17247e-07 (rank : 122)	NC score	0.725110 (rank : 22)
Query Neighborhood Hits	582	Target Neighborhood Hits	401	Shared Neighborhood Hits	332
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

MFGM_MOUSE
θ value	1.17247e-07 (rank : 123)	NC score	0.464139 (rank : 171)
Query Neighborhood Hits	582	Target Neighborhood Hits	233	Shared Neighborhood Hits	198
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

FBN1_MOUSE
θ value	1.99992e-07 (rank : 124)	NC score	0.584676 (rank : 83)
Query Neighborhood Hits	582	Target Neighborhood Hits	563	Shared Neighborhood Hits	365
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

KR106_HUMAN
θ value	1.99992e-07 (rank : 125)	NC score	0.534832 (rank : 123)
Query Neighborhood Hits	582	Target Neighborhood Hits	347	Shared Neighborhood Hits	250
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	3.41135e-07 (rank : 126)	NC score	0.535318 (rank : 122)
Query Neighborhood Hits	582	Target Neighborhood Hits	330	Shared Neighborhood Hits	241
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

FSTL5_MOUSE
θ value	4.45536e-07 (rank : 127)	NC score	0.143955 (rank : 450)
Query Neighborhood Hits	582	Target Neighborhood Hits	355	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

IBP7_HUMAN
θ value	4.45536e-07 (rank : 128)	NC score	0.172561 (rank : 394)
Query Neighborhood Hits	582	Target Neighborhood Hits	220	Shared Neighborhood Hits	48
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

KAZD1_HUMAN
θ value	4.45536e-07 (rank : 129)	NC score	0.182941 (rank : 371)
Query Neighborhood Hits	582	Target Neighborhood Hits	248	Shared Neighborhood Hits	64
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	4.45536e-07 (rank : 130)	NC score	0.166105 (rank : 406)
Query Neighborhood Hits	582	Target Neighborhood Hits	281	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

DNER_MOUSE
θ value	5.81887e-07 (rank : 131)	NC score	0.721249 (rank : 26)
Query Neighborhood Hits	582	Target Neighborhood Hits	413	Shared Neighborhood Hits	329
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

LAMA3_HUMAN
θ value	5.81887e-07 (rank : 132)	NC score	0.609339 (rank : 71)
Query Neighborhood Hits	582	Target Neighborhood Hits	760	Shared Neighborhood Hits	258
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

TIE1_HUMAN
θ value	5.81887e-07 (rank : 133)	NC score	0.211260 (rank : 342)
Query Neighborhood Hits	582	Target Neighborhood Hits	1241	Shared Neighborhood Hits	285
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CNTP1_HUMAN
θ value	7.59969e-07 (rank : 134)	NC score	0.420509 (rank : 212)
Query Neighborhood Hits	582	Target Neighborhood Hits	196	Shared Neighborhood Hits	127
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

DNER_HUMAN
θ value	7.59969e-07 (rank : 135)	NC score	0.721650 (rank : 25)
Query Neighborhood Hits	582	Target Neighborhood Hits	460	Shared Neighborhood Hits	341
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

TIE1_MOUSE
θ value	1.29631e-06 (rank : 136)	NC score	0.208671 (rank : 346)
Query Neighborhood Hits	582	Target Neighborhood Hits	1266	Shared Neighborhood Hits	289
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

KR510_HUMAN
θ value	1.69304e-06 (rank : 137)	NC score	0.488363 (rank : 148)
Query Neighborhood Hits	582	Target Neighborhood Hits	217	Shared Neighborhood Hits	153
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

CSPG4_HUMAN
θ value	2.21117e-06 (rank : 138)	NC score	0.210815 (rank : 343)
Query Neighborhood Hits	582	Target Neighborhood Hits	112	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

KRA52_HUMAN
θ value	2.21117e-06 (rank : 139)	NC score	0.493061 (rank : 145)
Query Neighborhood Hits	582	Target Neighborhood Hits	236	Shared Neighborhood Hits	174
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

SSPO_MOUSE
θ value	2.21117e-06 (rank : 140)	NC score	0.373078 (rank : 244)
Query Neighborhood Hits	582	Target Neighborhood Hits	800	Shared Neighborhood Hits	351
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TICN3_HUMAN
θ value	2.21117e-06 (rank : 141)	NC score	0.179314 (rank : 380)
Query Neighborhood Hits	582	Target Neighborhood Hits	82	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_MOUSE
θ value	2.21117e-06 (rank : 142)	NC score	0.184340 (rank : 367)
Query Neighborhood Hits	582	Target Neighborhood Hits	83	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

STAB1_HUMAN
θ value	2.88788e-06 (rank : 143)	NC score	0.636236 (rank : 63)
Query Neighborhood Hits	582	Target Neighborhood Hits	546	Shared Neighborhood Hits	356
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

CNTP1_MOUSE
θ value	3.77169e-06 (rank : 144)	NC score	0.416668 (rank : 223)
Query Neighborhood Hits	582	Target Neighborhood Hits	183	Shared Neighborhood Hits	118
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

STAB1_MOUSE
θ value	3.77169e-06 (rank : 145)	NC score	0.633160 (rank : 66)
Query Neighborhood Hits	582	Target Neighborhood Hits	566	Shared Neighborhood Hits	365
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_MOUSE
θ value	3.77169e-06 (rank : 146)	NC score	0.627599 (rank : 67)
Query Neighborhood Hits	582	Target Neighborhood Hits	528	Shared Neighborhood Hits	358
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

ADA12_MOUSE
θ value	4.92598e-06 (rank : 147)	NC score	0.121032 (rank : 494)
Query Neighborhood Hits	582	Target Neighborhood Hits	474	Shared Neighborhood Hits	139
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

EGFL9_HUMAN
θ value	6.43352e-06 (rank : 148)	NC score	0.706494 (rank : 32)
Query Neighborhood Hits	582	Target Neighborhood Hits	365	Shared Neighborhood Hits	316
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

SMOC1_MOUSE
θ value	6.43352e-06 (rank : 149)	NC score	0.183108 (rank : 370)
Query Neighborhood Hits	582	Target Neighborhood Hits	74	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

EGFL9_MOUSE
θ value	8.40245e-06 (rank : 150)	NC score	0.700267 (rank : 33)
Query Neighborhood Hits	582	Target Neighborhood Hits	379	Shared Neighborhood Hits	323
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

HABP2_HUMAN
θ value	8.40245e-06 (rank : 151)	NC score	0.317206 (rank : 273)
Query Neighborhood Hits	582	Target Neighborhood Hits	431	Shared Neighborhood Hits	249
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

ITB3_HUMAN
θ value	8.40245e-06 (rank : 152)	NC score	0.444438 (rank : 192)
Query Neighborhood Hits	582	Target Neighborhood Hits	325	Shared Neighborhood Hits	262
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

CUBN_HUMAN
θ value	1.09739e-05 (rank : 153)	NC score	0.543390 (rank : 116)
Query Neighborhood Hits	582	Target Neighborhood Hits	482	Shared Neighborhood Hits	323
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

GAS6_MOUSE
θ value	1.09739e-05 (rank : 154)	NC score	0.537917 (rank : 119)
Query Neighborhood Hits	582	Target Neighborhood Hits	343	Shared Neighborhood Hits	277
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ITB6_MOUSE
θ value	1.09739e-05 (rank : 155)	NC score	0.472721 (rank : 161)
Query Neighborhood Hits	582	Target Neighborhood Hits	341	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

LTB1L_HUMAN
θ value	1.09739e-05 (rank : 156)	NC score	0.536780 (rank : 120)
Query Neighborhood Hits	582	Target Neighborhood Hits	553	Shared Neighborhood Hits	330
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	1.09739e-05 (rank : 157)	NC score	0.536754 (rank : 121)
Query Neighborhood Hits	582	Target Neighborhood Hits	502	Shared Neighborhood Hits	319
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SPRL1_HUMAN
θ value	1.09739e-05 (rank : 158)	NC score	0.169602 (rank : 400)
Query Neighborhood Hits	582	Target Neighborhood Hits	231	Shared Neighborhood Hits	48
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

TICN1_MOUSE
θ value	1.09739e-05 (rank : 159)	NC score	0.167606 (rank : 403)
Query Neighborhood Hits	582	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN2_MOUSE
θ value	1.09739e-05 (rank : 160)	NC score	0.182470 (rank : 374)
Query Neighborhood Hits	582	Target Neighborhood Hits	69	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

KRA51_HUMAN
θ value	1.43324e-05 (rank : 161)	NC score	0.623983 (rank : 69)
Query Neighborhood Hits	582	Target Neighborhood Hits	288	Shared Neighborhood Hits	210
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LTB1L_MOUSE
θ value	1.43324e-05 (rank : 162)	NC score	0.534266 (rank : 124)
Query Neighborhood Hits	582	Target Neighborhood Hits	514	Shared Neighborhood Hits	334
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	1.43324e-05 (rank : 163)	NC score	0.532263 (rank : 125)
Query Neighborhood Hits	582	Target Neighborhood Hits	479	Shared Neighborhood Hits	314
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_MOUSE
θ value	1.43324e-05 (rank : 164)	NC score	0.551415 (rank : 109)
Query Neighborhood Hits	582	Target Neighborhood Hits	475	Shared Neighborhood Hits	335
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

TICN2_HUMAN
θ value	1.43324e-05 (rank : 165)	NC score	0.180125 (rank : 379)
Query Neighborhood Hits	582	Target Neighborhood Hits	68	Shared Neighborhood Hits	48
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

ITB5_HUMAN
θ value	1.87187e-05 (rank : 166)	NC score	0.453090 (rank : 184)
Query Neighborhood Hits	582	Target Neighborhood Hits	310	Shared Neighborhood Hits	250
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

EGFL7_HUMAN
θ value	2.44474e-05 (rank : 167)	NC score	0.527069 (rank : 130)
Query Neighborhood Hits	582	Target Neighborhood Hits	325	Shared Neighborhood Hits	259
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

IBP7_MOUSE
θ value	2.44474e-05 (rank : 168)	NC score	0.175314 (rank : 386)
Query Neighborhood Hits	582	Target Neighborhood Hits	230	Shared Neighborhood Hits	61
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

ITB3_MOUSE
θ value	2.44474e-05 (rank : 169)	NC score	0.428889 (rank : 206)
Query Neighborhood Hits	582	Target Neighborhood Hits	319	Shared Neighborhood Hits	249
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

CSPG2_HUMAN
θ value	3.19293e-05 (rank : 170)	NC score	0.434423 (rank : 202)
Query Neighborhood Hits	582	Target Neighborhood Hits	681	Shared Neighborhood Hits	269
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

SMOC1_HUMAN
θ value	3.19293e-05 (rank : 171)	NC score	0.177418 (rank : 382)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

VWF_MOUSE
θ value	3.19293e-05 (rank : 172)	NC score	0.263021 (rank : 307)
Query Neighborhood Hits	582	Target Neighborhood Hits	381	Shared Neighborhood Hits	203
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CSPG2_MOUSE
θ value	4.1701e-05 (rank : 173)	NC score	0.439053 (rank : 199)
Query Neighborhood Hits	582	Target Neighborhood Hits	711	Shared Neighborhood Hits	274
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CUBN_MOUSE
θ value	4.1701e-05 (rank : 174)	NC score	0.531387 (rank : 127)
Query Neighborhood Hits	582	Target Neighborhood Hits	477	Shared Neighborhood Hits	309
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

SPRL1_MOUSE
θ value	4.1701e-05 (rank : 175)	NC score	0.154908 (rank : 431)
Query Neighborhood Hits	582	Target Neighborhood Hits	403	Shared Neighborhood Hits	44
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TICN1_HUMAN
θ value	4.1701e-05 (rank : 176)	NC score	0.160627 (rank : 420)
Query Neighborhood Hits	582	Target Neighborhood Hits	70	Shared Neighborhood Hits	45
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

CSPG3_HUMAN
θ value	5.44631e-05 (rank : 177)	NC score	0.438715 (rank : 200)
Query Neighborhood Hits	582	Target Neighborhood Hits	676	Shared Neighborhood Hits	269
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

COMP_MOUSE
θ value	7.1131e-05 (rank : 178)	NC score	0.484119 (rank : 150)
Query Neighborhood Hits	582	Target Neighborhood Hits	290	Shared Neighborhood Hits	233
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

IPK1_HUMAN
θ value	7.1131e-05 (rank : 179)	NC score	0.208571 (rank : 347)
Query Neighborhood Hits	582	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

FA12_HUMAN
θ value	9.29e-05 (rank : 180)	NC score	0.217979 (rank : 335)
Query Neighborhood Hits	582	Target Neighborhood Hits	425	Shared Neighborhood Hits	220
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

HTRA1_HUMAN
θ value	9.29e-05 (rank : 181)	NC score	0.126451 (rank : 481)
Query Neighborhood Hits	582	Target Neighborhood Hits	155	Shared Neighborhood Hits	71
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

KRA53_HUMAN
θ value	9.29e-05 (rank : 182)	NC score	0.620562 (rank : 70)
Query Neighborhood Hits	582	Target Neighborhood Hits	331	Shared Neighborhood Hits	240
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

HABP2_MOUSE
θ value	0.000121331 (rank : 183)	NC score	0.317008 (rank : 274)
Query Neighborhood Hits	582	Target Neighborhood Hits	445	Shared Neighborhood Hits	257
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

ITB5_MOUSE
θ value	0.000121331 (rank : 184)	NC score	0.466867 (rank : 168)
Query Neighborhood Hits	582	Target Neighborhood Hits	329	Shared Neighborhood Hits	264
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

PROS_MOUSE
θ value	0.000121331 (rank : 185)	NC score	0.522934 (rank : 131)
Query Neighborhood Hits	582	Target Neighborhood Hits	330	Shared Neighborhood Hits	265
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	0.000121331 (rank : 186)	NC score	0.402757 (rank : 233)
Query Neighborhood Hits	582	Target Neighborhood Hits	422	Shared Neighborhood Hits	236
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

TSP4_MOUSE
θ value	0.000121331 (rank : 187)	NC score	0.489520 (rank : 147)
Query Neighborhood Hits	582	Target Neighborhood Hits	276	Shared Neighborhood Hits	239
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

CRIM1_HUMAN
θ value	0.000158464 (rank : 188)	NC score	0.478374 (rank : 158)
Query Neighborhood Hits	582	Target Neighborhood Hits	362	Shared Neighborhood Hits	227
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

FBLN2_MOUSE
θ value	0.000158464 (rank : 189)	NC score	0.492407 (rank : 146)
Query Neighborhood Hits	582	Target Neighborhood Hits	505	Shared Neighborhood Hits	291
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

C1QR1_HUMAN
θ value	0.00020696 (rank : 190)	NC score	0.506505 (rank : 133)
Query Neighborhood Hits	582	Target Neighborhood Hits	493	Shared Neighborhood Hits	277
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

GAS6_HUMAN
θ value	0.00020696 (rank : 191)	NC score	0.531575 (rank : 126)
Query Neighborhood Hits	582	Target Neighborhood Hits	348	Shared Neighborhood Hits	275
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

HGFA_MOUSE
θ value	0.00020696 (rank : 192)	NC score	0.231951 (rank : 325)
Query Neighborhood Hits	582	Target Neighborhood Hits	419	Shared Neighborhood Hits	222
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

KRA54_HUMAN
θ value	0.00020696 (rank : 193)	NC score	0.527282 (rank : 129)
Query Neighborhood Hits	582	Target Neighborhood Hits	270	Shared Neighborhood Hits	186
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

SMOC2_MOUSE
θ value	0.00020696 (rank : 194)	NC score	0.164703 (rank : 410)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

TSP3_HUMAN
θ value	0.00020696 (rank : 195)	NC score	0.435676 (rank : 201)
Query Neighborhood Hits	582	Target Neighborhood Hits	250	Shared Neighborhood Hits	198
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

ITB6_HUMAN
θ value	0.000270298 (rank : 196)	NC score	0.456803 (rank : 178)
Query Neighborhood Hits	582	Target Neighborhood Hits	318	Shared Neighborhood Hits	252
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

KR109_HUMAN
θ value	0.000270298 (rank : 197)	NC score	0.441321 (rank : 198)
Query Neighborhood Hits	582	Target Neighborhood Hits	226	Shared Neighborhood Hits	171
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

LRP1B_HUMAN
θ value	0.000270298 (rank : 198)	NC score	0.498431 (rank : 141)
Query Neighborhood Hits	582	Target Neighborhood Hits	602	Shared Neighborhood Hits	368
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SPRC_HUMAN
θ value	0.000270298 (rank : 199)	NC score	0.199180 (rank : 350)
Query Neighborhood Hits	582	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

TPA_HUMAN
θ value	0.000270298 (rank : 200)	NC score	0.138756 (rank : 458)
Query Neighborhood Hits	582	Target Neighborhood Hits	324	Shared Neighborhood Hits	154
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

EMR1_HUMAN
θ value	0.00035302 (rank : 201)	NC score	0.429364 (rank : 205)
Query Neighborhood Hits	582	Target Neighborhood Hits	382	Shared Neighborhood Hits	236
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

ISK7_HUMAN
θ value	0.00035302 (rank : 202)	NC score	0.182937 (rank : 372)
Query Neighborhood Hits	582	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

ITB7_MOUSE
θ value	0.00035302 (rank : 203)	NC score	0.458788 (rank : 174)
Query Neighborhood Hits	582	Target Neighborhood Hits	277	Shared Neighborhood Hits	232
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

KRA57_HUMAN
θ value	0.00035302 (rank : 204)	NC score	0.542564 (rank : 117)
Query Neighborhood Hits	582	Target Neighborhood Hits	269	Shared Neighborhood Hits	199
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

PCSK5_MOUSE
θ value	0.00035302 (rank : 205)	NC score	0.416422 (rank : 224)
Query Neighborhood Hits	582	Target Neighborhood Hits	613	Shared Neighborhood Hits	298
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

WIF1_MOUSE
θ value	0.00035302 (rank : 206)	NC score	0.681620 (rank : 40)
Query Neighborhood Hits	582	Target Neighborhood Hits	393	Shared Neighborhood Hits	330
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CSPG3_MOUSE
θ value	0.000461057 (rank : 207)	NC score	0.445393 (rank : 189)
Query Neighborhood Hits	582	Target Neighborhood Hits	657	Shared Neighborhood Hits	275
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

HTRA1_MOUSE
θ value	0.000461057 (rank : 208)	NC score	0.120997 (rank : 495)
Query Neighborhood Hits	582	Target Neighborhood Hits	140	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

NID2_MOUSE
θ value	0.000461057 (rank : 209)	NC score	0.482468 (rank : 153)
Query Neighborhood Hits	582	Target Neighborhood Hits	338	Shared Neighborhood Hits	255
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

KRA58_HUMAN
θ value	0.000602161 (rank : 210)	NC score	0.567508 (rank : 98)
Query Neighborhood Hits	582	Target Neighborhood Hits	324	Shared Neighborhood Hits	228
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

NID2_HUMAN
θ value	0.000602161 (rank : 211)	NC score	0.495665 (rank : 143)
Query Neighborhood Hits	582	Target Neighborhood Hits	456	Shared Neighborhood Hits	272
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

SMOC2_HUMAN
θ value	0.000602161 (rank : 212)	NC score	0.163549 (rank : 412)
Query Neighborhood Hits	582	Target Neighborhood Hits	88	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SPRC_MOUSE
θ value	0.000602161 (rank : 213)	NC score	0.198614 (rank : 351)
Query Neighborhood Hits	582	Target Neighborhood Hits	46	Shared Neighborhood Hits	44
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

ZAN_HUMAN
θ value	0.000602161 (rank : 214)	NC score	0.356941 (rank : 249)
Query Neighborhood Hits	582	Target Neighborhood Hits	679	Shared Neighborhood Hits	300
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ATRN_HUMAN
θ value	0.000786445 (rank : 215)	NC score	0.500651 (rank : 139)
Query Neighborhood Hits	582	Target Neighborhood Hits	525	Shared Neighborhood Hits	267
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

HTRA3_HUMAN
θ value	0.000786445 (rank : 216)	NC score	0.119176 (rank : 500)
Query Neighborhood Hits	582	Target Neighborhood Hits	152	Shared Neighborhood Hits	60
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

IPK2_HUMAN
θ value	0.000786445 (rank : 217)	NC score	0.169346 (rank : 401)
Query Neighborhood Hits	582	Target Neighborhood Hits	30	Shared Neighborhood Hits	29
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

NELL2_MOUSE
θ value	0.000786445 (rank : 218)	NC score	0.566903 (rank : 99)
Query Neighborhood Hits	582	Target Neighborhood Hits	436	Shared Neighborhood Hits	322
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

TSP4_HUMAN
θ value	0.000786445 (rank : 219)	NC score	0.483652 (rank : 151)
Query Neighborhood Hits	582	Target Neighborhood Hits	277	Shared Neighborhood Hits	231
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

ATRN_MOUSE
θ value	0.00102713 (rank : 220)	NC score	0.503513 (rank : 136)
Query Neighborhood Hits	582	Target Neighborhood Hits	519	Shared Neighborhood Hits	268
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

C1QR1_MOUSE
θ value	0.00102713 (rank : 221)	NC score	0.499854 (rank : 140)
Query Neighborhood Hits	582	Target Neighborhood Hits	342	Shared Neighborhood Hits	248
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

COMP_HUMAN
θ value	0.00102713 (rank : 222)	NC score	0.459579 (rank : 172)
Query Neighborhood Hits	582	Target Neighborhood Hits	258	Shared Neighborhood Hits	214
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

ISK3_MOUSE
θ value	0.00102713 (rank : 223)	NC score	0.176982 (rank : 384)
Query Neighborhood Hits	582	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

ITB2_MOUSE
θ value	0.00102713 (rank : 224)	NC score	0.458290 (rank : 175)
Query Neighborhood Hits	582	Target Neighborhood Hits	326	Shared Neighborhood Hits	268
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KRA55_HUMAN
θ value	0.00102713 (rank : 225)	NC score	0.568163 (rank : 96)
Query Neighborhood Hits	582	Target Neighborhood Hits	257	Shared Neighborhood Hits	189
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LRP1B_MOUSE
θ value	0.00102713 (rank : 226)	NC score	0.494667 (rank : 144)
Query Neighborhood Hits	582	Target Neighborhood Hits	606	Shared Neighborhood Hits	370
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP8_MOUSE
θ value	0.00102713 (rank : 227)	NC score	0.368580 (rank : 246)
Query Neighborhood Hits	582	Target Neighborhood Hits	385	Shared Neighborhood Hits	247
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

NELL2_HUMAN
θ value	0.00102713 (rank : 228)	NC score	0.568966 (rank : 94)
Query Neighborhood Hits	582	Target Neighborhood Hits	449	Shared Neighborhood Hits	326
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

PGCB_HUMAN
θ value	0.00102713 (rank : 229)	NC score	0.248259 (rank : 314)
Query Neighborhood Hits	582	Target Neighborhood Hits	478	Shared Neighborhood Hits	192
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

TIE2_HUMAN
θ value	0.00102713 (rank : 230)	NC score	0.182125 (rank : 376)
Query Neighborhood Hits	582	Target Neighborhood Hits	1192	Shared Neighborhood Hits	263
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

VLDLR_HUMAN
θ value	0.00102713 (rank : 231)	NC score	0.386776 (rank : 239)
Query Neighborhood Hits	582	Target Neighborhood Hits	383	Shared Neighborhood Hits	261
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	0.00102713 (rank : 232)	NC score	0.381728 (rank : 241)
Query Neighborhood Hits	582	Target Neighborhood Hits	360	Shared Neighborhood Hits	248
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

CSPG4_MOUSE
θ value	0.00134147 (rank : 233)	NC score	0.209629 (rank : 345)
Query Neighborhood Hits	582	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

ITB2_HUMAN
θ value	0.00134147 (rank : 234)	NC score	0.426250 (rank : 209)
Query Neighborhood Hits	582	Target Neighborhood Hits	282	Shared Neighborhood Hits	233
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KR10B_HUMAN
θ value	0.00134147 (rank : 235)	NC score	0.417387 (rank : 222)
Query Neighborhood Hits	582	Target Neighborhood Hits	269	Shared Neighborhood Hits	186
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

PGCB_MOUSE
θ value	0.00134147 (rank : 236)	NC score	0.267151 (rank : 304)
Query Neighborhood Hits	582	Target Neighborhood Hits	459	Shared Neighborhood Hits	195
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

SHBG_HUMAN
θ value	0.00134147 (rank : 237)	NC score	0.248176 (rank : 315)
Query Neighborhood Hits	582	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

TECTA_HUMAN
θ value	0.00134147 (rank : 238)	NC score	0.175360 (rank : 385)
Query Neighborhood Hits	582	Target Neighborhood Hits	239	Shared Neighborhood Hits	163
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

ADA12_HUMAN
θ value	0.00175202 (rank : 239)	NC score	0.124669 (rank : 484)
Query Neighborhood Hits	582	Target Neighborhood Hits	224	Shared Neighborhood Hits	144
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ISK7_MOUSE
θ value	0.00175202 (rank : 240)	NC score	0.155346 (rank : 428)
Query Neighborhood Hits	582	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

KR101_HUMAN
θ value	0.00175202 (rank : 241)	NC score	0.478581 (rank : 157)
Query Neighborhood Hits	582	Target Neighborhood Hits	261	Shared Neighborhood Hits	185
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

TIE2_MOUSE
θ value	0.00175202 (rank : 242)	NC score	0.184808 (rank : 366)
Query Neighborhood Hits	582	Target Neighborhood Hits	1204	Shared Neighborhood Hits	275
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

VASN_MOUSE
θ value	0.00175202 (rank : 243)	NC score	0.153496 (rank : 433)
Query Neighborhood Hits	582	Target Neighborhood Hits	426	Shared Neighborhood Hits	131
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

KR102_HUMAN
θ value	0.00228821 (rank : 244)	NC score	0.446266 (rank : 187)
Query Neighborhood Hits	582	Target Neighborhood Hits	264	Shared Neighborhood Hits	193
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KRA59_HUMAN
θ value	0.00228821 (rank : 245)	NC score	0.580484 (rank : 87)
Query Neighborhood Hits	582	Target Neighborhood Hits	310	Shared Neighborhood Hits	205
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

MUC5B_HUMAN
θ value	0.00228821 (rank : 246)	NC score	0.325968 (rank : 264)
Query Neighborhood Hits	582	Target Neighborhood Hits	1020	Shared Neighborhood Hits	305
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NELL1_HUMAN
θ value	0.00228821 (rank : 247)	NC score	0.586851 (rank : 80)
Query Neighborhood Hits	582	Target Neighborhood Hits	451	Shared Neighborhood Hits	332
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

TSP3_MOUSE
θ value	0.00228821 (rank : 248)	NC score	0.444979 (rank : 190)
Query Neighborhood Hits	582	Target Neighborhood Hits	247	Shared Neighborhood Hits	202
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

FA9_HUMAN
θ value	0.00298849 (rank : 249)	NC score	0.227346 (rank : 327)
Query Neighborhood Hits	582	Target Neighborhood Hits	421	Shared Neighborhood Hits	225
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

GRN_HUMAN
θ value	0.00298849 (rank : 250)	NC score	0.396088 (rank : 237)
Query Neighborhood Hits	582	Target Neighborhood Hits	268	Shared Neighborhood Hits	201
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

HTRA3_MOUSE
θ value	0.00298849 (rank : 251)	NC score	0.109897 (rank : 524)
Query Neighborhood Hits	582	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

MMRN1_HUMAN
θ value	0.00298849 (rank : 252)	NC score	0.221422 (rank : 333)
Query Neighborhood Hits	582	Target Neighborhood Hits	636	Shared Neighborhood Hits	153
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

TENN_MOUSE
θ value	0.00298849 (rank : 253)	NC score	0.325025 (rank : 265)
Query Neighborhood Hits	582	Target Neighborhood Hits	484	Shared Neighborhood Hits	257
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

HMCN1_HUMAN
θ value	0.00390308 (rank : 254)	NC score	0.318534 (rank : 271)
Query Neighborhood Hits	582	Target Neighborhood Hits	983	Shared Neighborhood Hits	285
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

MATN4_MOUSE
θ value	0.00390308 (rank : 255)	NC score	0.315987 (rank : 277)
Query Neighborhood Hits	582	Target Neighborhood Hits	277	Shared Neighborhood Hits	190
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

PROZ_MOUSE
θ value	0.00390308 (rank : 256)	NC score	0.403837 (rank : 232)
Query Neighborhood Hits	582	Target Neighborhood Hits	410	Shared Neighborhood Hits	228
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

WIF1_HUMAN
θ value	0.00390308 (rank : 257)	NC score	0.671805 (rank : 46)
Query Neighborhood Hits	582	Target Neighborhood Hits	392	Shared Neighborhood Hits	328
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CREL1_MOUSE
θ value	0.00509761 (rank : 258)	NC score	0.549559 (rank : 112)
Query Neighborhood Hits	582	Target Neighborhood Hits	524	Shared Neighborhood Hits	256
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EGF_MOUSE
θ value	0.00509761 (rank : 259)	NC score	0.465649 (rank : 170)
Query Neighborhood Hits	582	Target Neighborhood Hits	358	Shared Neighborhood Hits	272
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

KR105_HUMAN
θ value	0.00509761 (rank : 260)	NC score	0.446242 (rank : 188)
Query Neighborhood Hits	582	Target Neighborhood Hits	271	Shared Neighborhood Hits	201
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KRA47_HUMAN
θ value	0.00509761 (rank : 261)	NC score	0.348916 (rank : 254)
Query Neighborhood Hits	582	Target Neighborhood Hits	204	Shared Neighborhood Hits	150
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

HGFA_HUMAN
θ value	0.00665767 (rank : 262)	NC score	0.238625 (rank : 319)
Query Neighborhood Hits	582	Target Neighborhood Hits	436	Shared Neighborhood Hits	223
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LDLR_HUMAN
θ value	0.00665767 (rank : 263)	NC score	0.381482 (rank : 242)
Query Neighborhood Hits	582	Target Neighborhood Hits	375	Shared Neighborhood Hits	263
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1_HUMAN
θ value	0.00665767 (rank : 264)	NC score	0.504891 (rank : 135)
Query Neighborhood Hits	582	Target Neighborhood Hits	617	Shared Neighborhood Hits	371
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

TPA_MOUSE
θ value	0.00665767 (rank : 265)	NC score	0.140672 (rank : 453)
Query Neighborhood Hits	582	Target Neighborhood Hits	335	Shared Neighborhood Hits	162
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRBM_HUMAN
θ value	0.00665767 (rank : 266)	NC score	0.485467 (rank : 149)
Query Neighborhood Hits	582	Target Neighborhood Hits	339	Shared Neighborhood Hits	249
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

VASN_HUMAN
θ value	0.00665767 (rank : 267)	NC score	0.165511 (rank : 408)
Query Neighborhood Hits	582	Target Neighborhood Hits	449	Shared Neighborhood Hits	145
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

CO7_HUMAN
θ value	0.00869519 (rank : 268)	NC score	0.169041 (rank : 402)
Query Neighborhood Hits	582	Target Neighborhood Hits	278	Shared Neighborhood Hits	141
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

ENTK_MOUSE
θ value	0.00869519 (rank : 269)	NC score	0.052846 (rank : 794)
Query Neighborhood Hits	582	Target Neighborhood Hits	338	Shared Neighborhood Hits	68
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TECTA_MOUSE
θ value	0.00869519 (rank : 270)	NC score	0.188944 (rank : 359)
Query Neighborhood Hits	582	Target Neighborhood Hits	244	Shared Neighborhood Hits	174
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

CREL1_HUMAN
θ value	0.0113563 (rank : 271)	NC score	0.568872 (rank : 95)
Query Neighborhood Hits	582	Target Neighborhood Hits	441	Shared Neighborhood Hits	246
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

FBLN2_HUMAN
θ value	0.0113563 (rank : 272)	NC score	0.496981 (rank : 142)
Query Neighborhood Hits	582	Target Neighborhood Hits	392	Shared Neighborhood Hits	262
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

MAGE1_HUMAN
θ value	0.0113563 (rank : 273)	NC score	0.033549 (rank : 853)
Query Neighborhood Hits	582	Target Neighborhood Hits	1389	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SCUB3_HUMAN
θ value	0.0113563 (rank : 274)	NC score	0.501821 (rank : 138)
Query Neighborhood Hits	582	Target Neighborhood Hits	428	Shared Neighborhood Hits	267
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

VWF_HUMAN
θ value	0.0113563 (rank : 275)	NC score	0.291159 (rank : 293)
Query Neighborhood Hits	582	Target Neighborhood Hits	396	Shared Neighborhood Hits	229
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ADAM8_MOUSE
θ value	0.0148317 (rank : 276)	NC score	0.177368 (rank : 383)
Query Neighborhood Hits	582	Target Neighborhood Hits	326	Shared Neighborhood Hits	201
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

CEL_HUMAN
θ value	0.0148317 (rank : 277)	NC score	0.020986 (rank : 887)
Query Neighborhood Hits	582	Target Neighborhood Hits	896	Shared Neighborhood Hits	53
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EGFL7_MOUSE
θ value	0.0148317 (rank : 278)	NC score	0.504894 (rank : 134)
Query Neighborhood Hits	582	Target Neighborhood Hits	287	Shared Neighborhood Hits	237
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

HTRA4_HUMAN
θ value	0.0148317 (rank : 279)	NC score	0.099793 (rank : 545)
Query Neighborhood Hits	582	Target Neighborhood Hits	119	Shared Neighborhood Hits	42
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

IPK2_MOUSE
θ value	0.0148317 (rank : 280)	NC score	0.137043 (rank : 463)
Query Neighborhood Hits	582	Target Neighborhood Hits	26	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BMY7	Gene names	Spink2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 2 precursor.

ITB4_HUMAN
θ value	0.0148317 (rank : 281)	NC score	0.405590 (rank : 231)
Query Neighborhood Hits	582	Target Neighborhood Hits	458	Shared Neighborhood Hits	251
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

MDC1_HUMAN
θ value	0.0148317 (rank : 282)	NC score	0.040464 (rank : 842)
Query Neighborhood Hits	582	Target Neighborhood Hits	1446	Shared Neighborhood Hits	66
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SO2A1_MOUSE
θ value	0.0148317 (rank : 283)	NC score	0.059117 (rank : 722)
Query Neighborhood Hits	582	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

TENR_HUMAN
θ value	0.0148317 (rank : 284)	NC score	0.379600 (rank : 243)
Query Neighborhood Hits	582	Target Neighborhood Hits	526	Shared Neighborhood Hits	286
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

FBLN5_MOUSE
θ value	0.0193708 (rank : 285)	NC score	0.447313 (rank : 186)
Query Neighborhood Hits	582	Target Neighborhood Hits	317	Shared Neighborhood Hits	234
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

ISK4_HUMAN
θ value	0.0193708 (rank : 286)	NC score	0.183412 (rank : 368)
Query Neighborhood Hits	582	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

LDLR_MOUSE
θ value	0.0193708 (rank : 287)	NC score	0.365675 (rank : 247)
Query Neighborhood Hits	582	Target Neighborhood Hits	382	Shared Neighborhood Hits	259
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

NRX3B_HUMAN
θ value	0.0193708 (rank : 288)	NC score	0.257826 (rank : 309)
Query Neighborhood Hits	582	Target Neighborhood Hits	36	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HDB5	Gene names	NRXN3, KIAA0743
Domain Architecture	No domain graphic available
Description	Neurexin-3-beta precursor (Neurexin III-beta).

PROS_HUMAN
θ value	0.0193708 (rank : 289)	NC score	0.527604 (rank : 128)
Query Neighborhood Hits	582	Target Neighborhood Hits	340	Shared Neighborhood Hits	279
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SHBG_MOUSE
θ value	0.0193708 (rank : 290)	NC score	0.232664 (rank : 324)
Query Neighborhood Hits	582	Target Neighborhood Hits	50	Shared Neighborhood Hits	42
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SO4A1_HUMAN
θ value	0.0193708 (rank : 291)	NC score	0.059117 (rank : 721)
Query Neighborhood Hits	582	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

COGA1_HUMAN
θ value	0.0252991 (rank : 292)	NC score	0.040592 (rank : 841)
Query Neighborhood Hits	582	Target Neighborhood Hits	345	Shared Neighborhood Hits	47
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

FA10_MOUSE
θ value	0.0252991 (rank : 293)	NC score	0.233874 (rank : 323)
Query Neighborhood Hits	582	Target Neighborhood Hits	435	Shared Neighborhood Hits	231
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

GFRA3_HUMAN
θ value	0.0252991 (rank : 294)	NC score	0.033437 (rank : 855)
Query Neighborhood Hits	582	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

ITB1_MOUSE
θ value	0.0252991 (rank : 295)	NC score	0.419314 (rank : 215)
Query Neighborhood Hits	582	Target Neighborhood Hits	283	Shared Neighborhood Hits	219
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

NID1_HUMAN
θ value	0.0252991 (rank : 296)	NC score	0.483575 (rank : 152)
Query Neighborhood Hits	582	Target Neighborhood Hits	329	Shared Neighborhood Hits	257
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

ADA22_MOUSE
θ value	0.0330416 (rank : 297)	NC score	0.129424 (rank : 475)
Query Neighborhood Hits	582	Target Neighborhood Hits	225	Shared Neighborhood Hits	139
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

CO8B_MOUSE
θ value	0.0330416 (rank : 298)	NC score	0.154971 (rank : 430)
Query Neighborhood Hits	582	Target Neighborhood Hits	224	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

GRN_MOUSE
θ value	0.0330416 (rank : 299)	NC score	0.399116 (rank : 236)
Query Neighborhood Hits	582	Target Neighborhood Hits	248	Shared Neighborhood Hits	202
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KR103_HUMAN
θ value	0.0330416 (rank : 300)	NC score	0.344704 (rank : 257)
Query Neighborhood Hits	582	Target Neighborhood Hits	212	Shared Neighborhood Hits	155
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR10A_HUMAN
θ value	0.0330416 (rank : 301)	NC score	0.355062 (rank : 250)
Query Neighborhood Hits	582	Target Neighborhood Hits	232	Shared Neighborhood Hits	169
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KRA44_HUMAN
θ value	0.0330416 (rank : 302)	NC score	0.310203 (rank : 282)
Query Neighborhood Hits	582	Target Neighborhood Hits	162	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

NAGPA_HUMAN
θ value	0.0330416 (rank : 303)	NC score	0.552841 (rank : 107)
Query Neighborhood Hits	582	Target Neighborhood Hits	282	Shared Neighborhood Hits	232
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

SCUB3_MOUSE
θ value	0.0330416 (rank : 304)	NC score	0.502650 (rank : 137)
Query Neighborhood Hits	582	Target Neighborhood Hits	442	Shared Neighborhood Hits	276
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TENR_MOUSE
θ value	0.0330416 (rank : 305)	NC score	0.385315 (rank : 240)
Query Neighborhood Hits	582	Target Neighborhood Hits	531	Shared Neighborhood Hits	289
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

AD26A_MOUSE
θ value	0.0431538 (rank : 306)	NC score	0.094748 (rank : 553)
Query Neighborhood Hits	582	Target Neighborhood Hits	165	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADAM9_HUMAN
θ value	0.0431538 (rank : 307)	NC score	0.140108 (rank : 455)
Query Neighborhood Hits	582	Target Neighborhood Hits	243	Shared Neighborhood Hits	164
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

EPHA1_MOUSE
θ value	0.0431538 (rank : 308)	NC score	0.025152 (rank : 875)
Query Neighborhood Hits	582	Target Neighborhood Hits	958	Shared Neighborhood Hits	94
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

FA7_MOUSE
θ value	0.0431538 (rank : 309)	NC score	0.194454 (rank : 355)
Query Neighborhood Hits	582	Target Neighborhood Hits	374	Shared Neighborhood Hits	192
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

ISK4_MOUSE
θ value	0.0431538 (rank : 310)	NC score	0.170561 (rank : 398)
Query Neighborhood Hits	582	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

ITB7_HUMAN
θ value	0.0431538 (rank : 311)	NC score	0.457507 (rank : 177)
Query Neighborhood Hits	582	Target Neighborhood Hits	290	Shared Neighborhood Hits	237
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

KR108_HUMAN
θ value	0.0431538 (rank : 312)	NC score	0.419384 (rank : 214)
Query Neighborhood Hits	582	Target Neighborhood Hits	226	Shared Neighborhood Hits	167
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

LYAM2_MOUSE
θ value	0.0431538 (rank : 313)	NC score	0.300173 (rank : 288)
Query Neighborhood Hits	582	Target Neighborhood Hits	420	Shared Neighborhood Hits	251
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

NID1_MOUSE
θ value	0.0431538 (rank : 314)	NC score	0.477295 (rank : 159)
Query Neighborhood Hits	582	Target Neighborhood Hits	335	Shared Neighborhood Hits	250
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

ADAM9_MOUSE
θ value	0.0563607 (rank : 315)	NC score	0.149335 (rank : 440)
Query Neighborhood Hits	582	Target Neighborhood Hits	325	Shared Neighborhood Hits	185
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ITB1_HUMAN
θ value	0.0563607 (rank : 316)	NC score	0.418469 (rank : 217)
Query Neighborhood Hits	582	Target Neighborhood Hits	298	Shared Neighborhood Hits	232
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KRA11_HUMAN
θ value	0.0563607 (rank : 317)	NC score	0.350822 (rank : 253)
Query Neighborhood Hits	582	Target Neighborhood Hits	155	Shared Neighborhood Hits	123
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

PCSK5_HUMAN
θ value	0.0563607 (rank : 318)	NC score	0.225443 (rank : 329)
Query Neighborhood Hits	582	Target Neighborhood Hits	291	Shared Neighborhood Hits	168
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

TSP1_MOUSE
θ value	0.0563607 (rank : 319)	NC score	0.346115 (rank : 255)
Query Neighborhood Hits	582	Target Neighborhood Hits	396	Shared Neighborhood Hits	252
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

ADA22_HUMAN
θ value	0.0736092 (rank : 320)	NC score	0.121623 (rank : 492)
Query Neighborhood Hits	582	Target Neighborhood Hits	211	Shared Neighborhood Hits	132
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

FA7_HUMAN
θ value	0.0736092 (rank : 321)	NC score	0.216525 (rank : 336)
Query Neighborhood Hits	582	Target Neighborhood Hits	404	Shared Neighborhood Hits	213
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

KRA13_HUMAN
θ value	0.0736092 (rank : 322)	NC score	0.336140 (rank : 260)
Query Neighborhood Hits	582	Target Neighborhood Hits	144	Shared Neighborhood Hits	114
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

MCSP_MOUSE
θ value	0.0736092 (rank : 323)	NC score	0.186525 (rank : 364)
Query Neighborhood Hits	582	Target Neighborhood Hits	108	Shared Neighborhood Hits	60
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

TNR4_MOUSE
θ value	0.0736092 (rank : 324)	NC score	0.188899 (rank : 360)
Query Neighborhood Hits	582	Target Neighborhood Hits	137	Shared Neighborhood Hits	74
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

CFAI_HUMAN
θ value	0.0961366 (rank : 325)	NC score	0.067732 (rank : 657)
Query Neighborhood Hits	582	Target Neighborhood Hits	289	Shared Neighborhood Hits	77
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

ISK6_MOUSE
θ value	0.0961366 (rank : 326)	NC score	0.174640 (rank : 388)
Query Neighborhood Hits	582	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

KR511_HUMAN
θ value	0.0961366 (rank : 327)	NC score	0.480809 (rank : 154)
Query Neighborhood Hits	582	Target Neighborhood Hits	231	Shared Neighborhood Hits	170
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

PGCA_HUMAN
θ value	0.0961366 (rank : 328)	NC score	0.187157 (rank : 363)
Query Neighborhood Hits	582	Target Neighborhood Hits	821	Shared Neighborhood Hits	204
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

UROM_HUMAN
θ value	0.0961366 (rank : 329)	NC score	0.467846 (rank : 167)
Query Neighborhood Hits	582	Target Neighborhood Hits	284	Shared Neighborhood Hits	231
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ADA15_HUMAN
θ value	0.125558 (rank : 330)	NC score	0.161235 (rank : 418)
Query Neighborhood Hits	582	Target Neighborhood Hits	288	Shared Neighborhood Hits	198
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ATS20_HUMAN
θ value	0.125558 (rank : 331)	NC score	0.046018 (rank : 836)
Query Neighborhood Hits	582	Target Neighborhood Hits	192	Shared Neighborhood Hits	77
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

CFAI_MOUSE
θ value	0.125558 (rank : 332)	NC score	0.077591 (rank : 608)
Query Neighborhood Hits	582	Target Neighborhood Hits	290	Shared Neighborhood Hits	88
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

FBLN3_HUMAN
θ value	0.125558 (rank : 333)	NC score	0.432583 (rank : 203)
Query Neighborhood Hits	582	Target Neighborhood Hits	293	Shared Neighborhood Hits	227
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

ISK6_HUMAN
θ value	0.125558 (rank : 334)	NC score	0.175142 (rank : 387)
Query Neighborhood Hits	582	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

LCE2A_HUMAN
θ value	0.125558 (rank : 335)	NC score	0.223828 (rank : 331)
Query Neighborhood Hits	582	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

MUC2_HUMAN
θ value	0.125558 (rank : 336)	NC score	0.220525 (rank : 334)
Query Neighborhood Hits	582	Target Neighborhood Hits	906	Shared Neighborhood Hits	226
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

NFX1_HUMAN
θ value	0.125558 (rank : 337)	NC score	0.315104 (rank : 278)
Query Neighborhood Hits	582	Target Neighborhood Hits	405	Shared Neighborhood Hits	167
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

ADA33_HUMAN
θ value	0.163984 (rank : 338)	NC score	0.144475 (rank : 447)
Query Neighborhood Hits	582	Target Neighborhood Hits	264	Shared Neighborhood Hits	168
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CAMKV_HUMAN
θ value	0.163984 (rank : 339)	NC score	-0.004401 (rank : 942)
Query Neighborhood Hits	582	Target Neighborhood Hits	1084	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

FBLN1_MOUSE
θ value	0.163984 (rank : 340)	NC score	0.480233 (rank : 155)
Query Neighborhood Hits	582	Target Neighborhood Hits	329	Shared Neighborhood Hits	243
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN5_HUMAN
θ value	0.163984 (rank : 341)	NC score	0.452525 (rank : 185)
Query Neighborhood Hits	582	Target Neighborhood Hits	329	Shared Neighborhood Hits	245
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

KR171_HUMAN
θ value	0.163984 (rank : 342)	NC score	0.456034 (rank : 180)
Query Neighborhood Hits	582	Target Neighborhood Hits	144	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

MATN4_HUMAN
θ value	0.163984 (rank : 343)	NC score	0.339263 (rank : 259)
Query Neighborhood Hits	582	Target Neighborhood Hits	287	Shared Neighborhood Hits	199
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

SPR1B_MOUSE
θ value	0.163984 (rank : 344)	NC score	0.026466 (rank : 869)
Query Neighborhood Hits	582	Target Neighborhood Hits	395	Shared Neighborhood Hits	39
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

KRA56_HUMAN
θ value	0.21417 (rank : 345)	NC score	0.478795 (rank : 156)
Query Neighborhood Hits	582	Target Neighborhood Hits	207	Shared Neighborhood Hits	164
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

NAGPA_MOUSE
θ value	0.21417 (rank : 346)	NC score	0.561399 (rank : 102)
Query Neighborhood Hits	582	Target Neighborhood Hits	308	Shared Neighborhood Hits	255
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

RGS3_HUMAN
θ value	0.21417 (rank : 347)	NC score	0.010685 (rank : 913)
Query Neighborhood Hits	582	Target Neighborhood Hits	1375	Shared Neighborhood Hits	64
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SO3A1_HUMAN
θ value	0.21417 (rank : 348)	NC score	0.059489 (rank : 716)
Query Neighborhood Hits	582	Target Neighborhood Hits	54	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

SO3A1_MOUSE
θ value	0.21417 (rank : 349)	NC score	0.059954 (rank : 710)
Query Neighborhood Hits	582	Target Neighborhood Hits	59	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

TENN_HUMAN
θ value	0.21417 (rank : 350)	NC score	0.313979 (rank : 279)
Query Neighborhood Hits	582	Target Neighborhood Hits	453	Shared Neighborhood Hits	260
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TSP1_HUMAN
θ value	0.21417 (rank : 351)	NC score	0.339799 (rank : 258)
Query Neighborhood Hits	582	Target Neighborhood Hits	389	Shared Neighborhood Hits	250
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

EMR2_HUMAN
θ value	0.279714 (rank : 352)	NC score	0.405639 (rank : 230)
Query Neighborhood Hits	582	Target Neighborhood Hits	345	Shared Neighborhood Hits	218
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FBLN3_MOUSE
θ value	0.279714 (rank : 353)	NC score	0.418368 (rank : 219)
Query Neighborhood Hits	582	Target Neighborhood Hits	279	Shared Neighborhood Hits	214
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

K0319_MOUSE
θ value	0.279714 (rank : 354)	NC score	0.035505 (rank : 849)
Query Neighborhood Hits	582	Target Neighborhood Hits	134	Shared Neighborhood Hits	24
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

KRA92_HUMAN
θ value	0.279714 (rank : 355)	NC score	0.302031 (rank : 287)
Query Neighborhood Hits	582	Target Neighborhood Hits	198	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

PROC_MOUSE
θ value	0.279714 (rank : 356)	NC score	0.213952 (rank : 339)
Query Neighborhood Hits	582	Target Neighborhood Hits	426	Shared Neighborhood Hits	230
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

SCRT1_HUMAN
θ value	0.279714 (rank : 357)	NC score	-0.012196 (rank : 949)
Query Neighborhood Hits	582	Target Neighborhood Hits	706	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BWW7, Q96C52	Gene names	SCRT1
Domain Architecture	No domain graphic available
Description	Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (Scratch 1) (SCRT) (hScrt).

TNR16_MOUSE
θ value	0.279714 (rank : 358)	NC score	0.173500 (rank : 392)
Query Neighborhood Hits	582	Target Neighborhood Hits	178	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

UROM_MOUSE
θ value	0.279714 (rank : 359)	NC score	0.457555 (rank : 176)
Query Neighborhood Hits	582	Target Neighborhood Hits	276	Shared Neighborhood Hits	230
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ADA10_MOUSE
θ value	0.365318 (rank : 360)	NC score	0.131752 (rank : 472)
Query Neighborhood Hits	582	Target Neighborhood Hits	194	Shared Neighborhood Hits	128
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA18_MOUSE
θ value	0.365318 (rank : 361)	NC score	0.133460 (rank : 468)
Query Neighborhood Hits	582	Target Neighborhood Hits	227	Shared Neighborhood Hits	166
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA32_MOUSE
θ value	0.365318 (rank : 362)	NC score	0.112426 (rank : 520)
Query Neighborhood Hits	582	Target Neighborhood Hits	219	Shared Neighborhood Hits	154
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

CTGF_HUMAN
θ value	0.365318 (rank : 363)	NC score	0.089043 (rank : 565)
Query Neighborhood Hits	582	Target Neighborhood Hits	128	Shared Neighborhood Hits	70
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

EHMT2_MOUSE
θ value	0.365318 (rank : 364)	NC score	0.040178 (rank : 843)
Query Neighborhood Hits	582	Target Neighborhood Hits	750	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

F19A4_MOUSE
θ value	0.365318 (rank : 365)	NC score	0.030568 (rank : 862)
Query Neighborhood Hits	582	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TPG5, Q5FWC0, Q8BV02	Gene names	Fam19a4, Tafa4
Domain Architecture	No domain graphic available
Description	Protein FAM19A4 precursor (Chemokine-like protein TAFA-4).

LRP2_HUMAN
θ value	0.365318 (rank : 366)	NC score	0.409174 (rank : 228)
Query Neighborhood Hits	582	Target Neighborhood Hits	573	Shared Neighborhood Hits	362
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

NACAM_MOUSE
θ value	0.365318 (rank : 367)	NC score	0.039678 (rank : 845)
Query Neighborhood Hits	582	Target Neighborhood Hits	1866	Shared Neighborhood Hits	101
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PERT_HUMAN
θ value	0.365318 (rank : 368)	NC score	0.172799 (rank : 393)
Query Neighborhood Hits	582	Target Neighborhood Hits	221	Shared Neighborhood Hits	136
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

SPEG_HUMAN
θ value	0.365318 (rank : 369)	NC score	0.020226 (rank : 889)
Query Neighborhood Hits	582	Target Neighborhood Hits	1762	Shared Neighborhood Hits	90
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ADA28_HUMAN
θ value	0.47712 (rank : 370)	NC score	0.123602 (rank : 486)
Query Neighborhood Hits	582	Target Neighborhood Hits	244	Shared Neighborhood Hits	162
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA32_HUMAN
θ value	0.47712 (rank : 371)	NC score	0.116791 (rank : 507)
Query Neighborhood Hits	582	Target Neighborhood Hits	216	Shared Neighborhood Hits	147
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

CORIN_MOUSE
θ value	0.47712 (rank : 372)	NC score	0.146622 (rank : 442)
Query Neighborhood Hits	582	Target Neighborhood Hits	451	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

ELTD1_HUMAN
θ value	0.47712 (rank : 373)	NC score	0.274398 (rank : 300)
Query Neighborhood Hits	582	Target Neighborhood Hits	269	Shared Neighborhood Hits	168
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

EMR1_MOUSE
θ value	0.47712 (rank : 374)	NC score	0.395162 (rank : 238)
Query Neighborhood Hits	582	Target Neighborhood Hits	349	Shared Neighborhood Hits	219
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EPHA2_HUMAN
θ value	0.47712 (rank : 375)	NC score	0.023474 (rank : 881)
Query Neighborhood Hits	582	Target Neighborhood Hits	1021	Shared Neighborhood Hits	88
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

FBLN4_HUMAN
θ value	0.47712 (rank : 376)	NC score	0.453217 (rank : 183)
Query Neighborhood Hits	582	Target Neighborhood Hits	278	Shared Neighborhood Hits	222
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

KR10C_HUMAN
θ value	0.47712 (rank : 377)	NC score	0.419691 (rank : 213)
Query Neighborhood Hits	582	Target Neighborhood Hits	219	Shared Neighborhood Hits	170
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

LPP_HUMAN
θ value	0.47712 (rank : 378)	NC score	0.012569 (rank : 906)
Query Neighborhood Hits	582	Target Neighborhood Hits	775	Shared Neighborhood Hits	52
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

LYAM3_MOUSE
θ value	0.47712 (rank : 379)	NC score	0.293913 (rank : 291)
Query Neighborhood Hits	582	Target Neighborhood Hits	390	Shared Neighborhood Hits	227
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

SO4A1_MOUSE
θ value	0.47712 (rank : 380)	NC score	0.052495 (rank : 799)
Query Neighborhood Hits	582	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

SOX30_MOUSE
θ value	0.47712 (rank : 381)	NC score	0.009477 (rank : 916)
Query Neighborhood Hits	582	Target Neighborhood Hits	374	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SRPX_HUMAN
θ value	0.47712 (rank : 382)	NC score	0.035213 (rank : 850)
Query Neighborhood Hits	582	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

TRBM_MOUSE
θ value	0.47712 (rank : 383)	NC score	0.466792 (rank : 169)
Query Neighborhood Hits	582	Target Neighborhood Hits	361	Shared Neighborhood Hits	245
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ADAM2_MOUSE
θ value	0.62314 (rank : 384)	NC score	0.133439 (rank : 469)
Query Neighborhood Hits	582	Target Neighborhood Hits	209	Shared Neighborhood Hits	144
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

CD248_HUMAN
θ value	0.62314 (rank : 385)	NC score	0.368907 (rank : 245)
Query Neighborhood Hits	582	Target Neighborhood Hits	679	Shared Neighborhood Hits	245
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	0.62314 (rank : 386)	NC score	0.364785 (rank : 248)
Query Neighborhood Hits	582	Target Neighborhood Hits	578	Shared Neighborhood Hits	219
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

DGKI_HUMAN
θ value	0.62314 (rank : 387)	NC score	0.016740 (rank : 898)
Query Neighborhood Hits	582	Target Neighborhood Hits	609	Shared Neighborhood Hits	16
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

EGF_HUMAN
θ value	0.62314 (rank : 388)	NC score	0.423297 (rank : 210)
Query Neighborhood Hits	582	Target Neighborhood Hits	343	Shared Neighborhood Hits	247
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EPHA3_HUMAN
θ value	0.62314 (rank : 389)	NC score	0.024628 (rank : 877)
Query Neighborhood Hits	582	Target Neighborhood Hits	1005	Shared Neighborhood Hits	89
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

FBLN1_HUMAN
θ value	0.62314 (rank : 390)	NC score	0.472662 (rank : 162)
Query Neighborhood Hits	582	Target Neighborhood Hits	324	Shared Neighborhood Hits	248
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

ITB8_HUMAN
θ value	0.62314 (rank : 391)	NC score	0.354481 (rank : 251)
Query Neighborhood Hits	582	Target Neighborhood Hits	280	Shared Neighborhood Hits	218
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

LOXL3_MOUSE
θ value	0.62314 (rank : 392)	NC score	0.006842 (rank : 922)
Query Neighborhood Hits	582	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z175, Q9JJ39	Gene names	Loxl3, Lor2
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3) (Lysyl oxidase-related protein 2).

LRP5_HUMAN
θ value	0.62314 (rank : 393)	NC score	0.158735 (rank : 424)
Query Neighborhood Hits	582	Target Neighborhood Hits	224	Shared Neighborhood Hits	134
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LYAM3_HUMAN
θ value	0.62314 (rank : 394)	NC score	0.266352 (rank : 305)
Query Neighborhood Hits	582	Target Neighborhood Hits	378	Shared Neighborhood Hits	214
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

RFX1_HUMAN
θ value	0.62314 (rank : 395)	NC score	0.025731 (rank : 872)
Query Neighborhood Hits	582	Target Neighborhood Hits	256	Shared Neighborhood Hits	36
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

SO1B1_HUMAN
θ value	0.62314 (rank : 396)	NC score	0.052665 (rank : 795)
Query Neighborhood Hits	582	Target Neighborhood Hits	43	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

ADA10_HUMAN
θ value	0.813845 (rank : 397)	NC score	0.134664 (rank : 466)
Query Neighborhood Hits	582	Target Neighborhood Hits	189	Shared Neighborhood Hits	129
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

EGFL8_HUMAN
θ value	0.813845 (rank : 398)	NC score	0.470208 (rank : 166)
Query Neighborhood Hits	582	Target Neighborhood Hits	270	Shared Neighborhood Hits	214
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EPHB4_HUMAN
θ value	0.813845 (rank : 399)	NC score	0.046813 (rank : 835)
Query Neighborhood Hits	582	Target Neighborhood Hits	1056	Shared Neighborhood Hits	140
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

KRA15_HUMAN
θ value	0.813845 (rank : 400)	NC score	0.296637 (rank : 290)
Query Neighborhood Hits	582	Target Neighborhood Hits	126	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

LRP5_MOUSE
θ value	0.813845 (rank : 401)	NC score	0.165829 (rank : 407)
Query Neighborhood Hits	582	Target Neighborhood Hits	236	Shared Neighborhood Hits	142
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

MFGM_HUMAN
θ value	0.813845 (rank : 402)	NC score	0.265704 (rank : 306)
Query Neighborhood Hits	582	Target Neighborhood Hits	150	Shared Neighborhood Hits	125
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MUC1_HUMAN
θ value	0.813845 (rank : 403)	NC score	0.030355 (rank : 863)
Query Neighborhood Hits	582	Target Neighborhood Hits	975	Shared Neighborhood Hits	68
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SO1B2_MOUSE
θ value	0.813845 (rank : 404)	NC score	0.052949 (rank : 793)
Query Neighborhood Hits	582	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJL3, Q9JI79, Q9JJJ1	Gene names	Slco1b2, Slc21a10
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B2 (Solute carrier family 21 member 10) (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6).

SPR1A_MOUSE
θ value	0.813845 (rank : 405)	NC score	0.024729 (rank : 876)
Query Neighborhood Hits	582	Target Neighborhood Hits	343	Shared Neighborhood Hits	32
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SRPX_MOUSE
θ value	0.813845 (rank : 406)	NC score	0.035998 (rank : 847)
Query Neighborhood Hits	582	Target Neighborhood Hits	75	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

TSP2_HUMAN
θ value	0.813845 (rank : 407)	NC score	0.308900 (rank : 284)
Query Neighborhood Hits	582	Target Neighborhood Hits	359	Shared Neighborhood Hits	234
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	0.813845 (rank : 408)	NC score	0.309144 (rank : 283)
Query Neighborhood Hits	582	Target Neighborhood Hits	352	Shared Neighborhood Hits	231
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ZNFX1_MOUSE
θ value	0.813845 (rank : 409)	NC score	0.120359 (rank : 497)
Query Neighborhood Hits	582	Target Neighborhood Hits	407	Shared Neighborhood Hits	117
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ADA15_MOUSE
θ value	1.06291 (rank : 410)	NC score	0.170730 (rank : 396)
Query Neighborhood Hits	582	Target Neighborhood Hits	324	Shared Neighborhood Hits	218
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_MOUSE
θ value	1.06291 (rank : 411)	NC score	0.112848 (rank : 517)
Query Neighborhood Hits	582	Target Neighborhood Hits	201	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA19_HUMAN
θ value	1.06291 (rank : 412)	NC score	0.141305 (rank : 452)
Query Neighborhood Hits	582	Target Neighborhood Hits	381	Shared Neighborhood Hits	181
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA24_MOUSE
θ value	1.06291 (rank : 413)	NC score	0.115876 (rank : 508)
Query Neighborhood Hits	582	Target Neighborhood Hits	230	Shared Neighborhood Hits	161
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA30_HUMAN
θ value	1.06291 (rank : 414)	NC score	0.112846 (rank : 518)
Query Neighborhood Hits	582	Target Neighborhood Hits	391	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

CD97_HUMAN
θ value	1.06291 (rank : 415)	NC score	0.401639 (rank : 235)
Query Neighborhood Hits	582	Target Neighborhood Hits	353	Shared Neighborhood Hits	224
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

EPHA3_MOUSE
θ value	1.06291 (rank : 416)	NC score	0.025673 (rank : 873)
Query Neighborhood Hits	582	Target Neighborhood Hits	1009	Shared Neighborhood Hits	84
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHB6_HUMAN
θ value	1.06291 (rank : 417)	NC score	0.032251 (rank : 858)
Query Neighborhood Hits	582	Target Neighborhood Hits	912	Shared Neighborhood Hits	87
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

ERBB3_HUMAN
θ value	1.06291 (rank : 418)	NC score	0.032694 (rank : 856)
Query Neighborhood Hits	582	Target Neighborhood Hits	918	Shared Neighborhood Hits	105
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

FA10_HUMAN
θ value	1.06291 (rank : 419)	NC score	0.226634 (rank : 328)
Query Neighborhood Hits	582	Target Neighborhood Hits	431	Shared Neighborhood Hits	228
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

KRA94_HUMAN
θ value	1.06291 (rank : 420)	NC score	0.319950 (rank : 269)
Query Neighborhood Hits	582	Target Neighborhood Hits	204	Shared Neighborhood Hits	153
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

SO1A1_MOUSE
θ value	1.06291 (rank : 421)	NC score	0.048444 (rank : 831)
Query Neighborhood Hits	582	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SO1A4_MOUSE
θ value	1.06291 (rank : 422)	NC score	0.048980 (rank : 830)
Query Neighborhood Hits	582	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EP96	Gene names	Slco1a4, Oatp2, Slc21a5
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A4 (Solute carrier family 21 member 5) (Sodium-independent organic anion- transporting polypeptide 2).

SO1A5_MOUSE
θ value	1.06291 (rank : 423)	NC score	0.050006 (rank : 828)
Query Neighborhood Hits	582	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	Q91YY5, Q91XS2	Gene names	Slco1a5, Oatp3, Slc21a7
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A5 (Solute carrier family 21 member 7) (Sodium-independent organic anion transporter 3) (Organic anion-transporting polypeptide 3).

SO1B3_HUMAN
θ value	1.06291 (rank : 424)	NC score	0.053111 (rank : 788)
Query Neighborhood Hits	582	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

SO2A1_HUMAN
θ value	1.06291 (rank : 425)	NC score	0.056290 (rank : 745)
Query Neighborhood Hits	582	Target Neighborhood Hits	40	Shared Neighborhood Hits	34
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO5A1_HUMAN
θ value	1.06291 (rank : 426)	NC score	0.056213 (rank : 747)
Query Neighborhood Hits	582	Target Neighborhood Hits	57	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

AAK1_HUMAN
θ value	1.38821 (rank : 427)	NC score	0.000208 (rank : 935)
Query Neighborhood Hits	582	Target Neighborhood Hits	1077	Shared Neighborhood Hits	46
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ADA11_HUMAN
θ value	1.38821 (rank : 428)	NC score	0.159010 (rank : 423)
Query Neighborhood Hits	582	Target Neighborhood Hits	259	Shared Neighborhood Hits	180
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	1.38821 (rank : 429)	NC score	0.158360 (rank : 426)
Query Neighborhood Hits	582	Target Neighborhood Hits	263	Shared Neighborhood Hits	180
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA29_HUMAN
θ value	1.38821 (rank : 430)	NC score	0.096340 (rank : 552)
Query Neighborhood Hits	582	Target Neighborhood Hits	247	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADAM8_HUMAN
θ value	1.38821 (rank : 431)	NC score	0.170678 (rank : 397)
Query Neighborhood Hits	582	Target Neighborhood Hits	327	Shared Neighborhood Hits	215
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

FBLN4_MOUSE
θ value	1.38821 (rank : 432)	NC score	0.444947 (rank : 191)
Query Neighborhood Hits	582	Target Neighborhood Hits	270	Shared Neighborhood Hits	214
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

HEMGN_MOUSE
θ value	1.38821 (rank : 433)	NC score	0.018352 (rank : 893)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

KR414_HUMAN
θ value	1.38821 (rank : 434)	NC score	0.332038 (rank : 262)
Query Neighborhood Hits	582	Target Neighborhood Hits	199	Shared Neighborhood Hits	148
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

LRP8_HUMAN
θ value	1.38821 (rank : 435)	NC score	0.345490 (rank : 256)
Query Neighborhood Hits	582	Target Neighborhood Hits	346	Shared Neighborhood Hits	229
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

SO1A2_HUMAN
θ value	1.38821 (rank : 436)	NC score	0.052977 (rank : 792)
Query Neighborhood Hits	582	Target Neighborhood Hits	40	Shared Neighborhood Hits	31
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

T22D4_HUMAN
θ value	1.38821 (rank : 437)	NC score	0.016902 (rank : 897)
Query Neighborhood Hits	582	Target Neighborhood Hits	403	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TARSH_HUMAN
θ value	1.38821 (rank : 438)	NC score	0.045213 (rank : 838)
Query Neighborhood Hits	582	Target Neighborhood Hits	768	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TDGF1_HUMAN
θ value	1.38821 (rank : 439)	NC score	0.277946 (rank : 297)
Query Neighborhood Hits	582	Target Neighborhood Hits	132	Shared Neighborhood Hits	126
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF2_HUMAN
θ value	1.38821 (rank : 440)	NC score	0.267585 (rank : 303)
Query Neighborhood Hits	582	Target Neighborhood Hits	131	Shared Neighborhood Hits	122
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

UROK_HUMAN
θ value	1.38821 (rank : 441)	NC score	0.078404 (rank : 602)
Query Neighborhood Hits	582	Target Neighborhood Hits	272	Shared Neighborhood Hits	109
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

COCA1_HUMAN
θ value	1.81305 (rank : 442)	NC score	0.052155 (rank : 805)
Query Neighborhood Hits	582	Target Neighborhood Hits	458	Shared Neighborhood Hits	50
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

EPGN_MOUSE
θ value	1.81305 (rank : 443)	NC score	0.133817 (rank : 467)
Query Neighborhood Hits	582	Target Neighborhood Hits	63	Shared Neighborhood Hits	45
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EPHA1_HUMAN
θ value	1.81305 (rank : 444)	NC score	0.029713 (rank : 865)
Query Neighborhood Hits	582	Target Neighborhood Hits	997	Shared Neighborhood Hits	111
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

ESM1_MOUSE
θ value	1.81305 (rank : 445)	NC score	0.231000 (rank : 326)
Query Neighborhood Hits	582	Target Neighborhood Hits	107	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

F19A5_HUMAN
θ value	1.81305 (rank : 446)	NC score	0.022971 (rank : 884)
Query Neighborhood Hits	582	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z5A7, O95902, Q5H9C4, Q6UWC9, Q8IXR8	Gene names	FAM19A5, TAFA5
Domain Architecture	No domain graphic available
Description	Protein FAM19A5 precursor (Chemokine-like protein TAFA-5).

F19A5_MOUSE
θ value	1.81305 (rank : 447)	NC score	0.022971 (rank : 885)
Query Neighborhood Hits	582	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WE9, Q8C1V6	Gene names	Fam19a5, Tafa5
Domain Architecture	No domain graphic available
Description	Protein FAM19A5 precursor (Chemokine-like protein TAFA-5).

GP123_HUMAN
θ value	1.81305 (rank : 448)	NC score	0.072268 (rank : 629)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

KR122_HUMAN
θ value	1.81305 (rank : 449)	NC score	0.166705 (rank : 404)
Query Neighborhood Hits	582	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KRA24_HUMAN
θ value	1.81305 (rank : 450)	NC score	0.214466 (rank : 338)
Query Neighborhood Hits	582	Target Neighborhood Hits	192	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA42_HUMAN
θ value	1.81305 (rank : 451)	NC score	0.222562 (rank : 332)
Query Neighborhood Hits	582	Target Neighborhood Hits	149	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

LRP10_MOUSE
θ value	1.81305 (rank : 452)	NC score	0.137640 (rank : 462)
Query Neighborhood Hits	582	Target Neighborhood Hits	169	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

SORL_MOUSE
θ value	1.81305 (rank : 453)	NC score	0.286123 (rank : 294)
Query Neighborhood Hits	582	Target Neighborhood Hits	439	Shared Neighborhood Hits	229
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TDGF1_MOUSE
θ value	1.81305 (rank : 454)	NC score	0.323155 (rank : 268)
Query Neighborhood Hits	582	Target Neighborhood Hits	146	Shared Neighborhood Hits	139
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

WISP1_MOUSE
θ value	1.81305 (rank : 455)	NC score	0.067783 (rank : 656)
Query Neighborhood Hits	582	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

ATS3_HUMAN
θ value	2.36792 (rank : 456)	NC score	0.034688 (rank : 851)
Query Neighborhood Hits	582	Target Neighborhood Hits	179	Shared Neighborhood Hits	63
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

CO9_MOUSE
θ value	2.36792 (rank : 457)	NC score	0.128401 (rank : 477)
Query Neighborhood Hits	582	Target Neighborhood Hits	153	Shared Neighborhood Hits	91
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CTGF_MOUSE
θ value	2.36792 (rank : 458)	NC score	0.079690 (rank : 598)
Query Neighborhood Hits	582	Target Neighborhood Hits	124	Shared Neighborhood Hits	71
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

F19A4_HUMAN
θ value	2.36792 (rank : 459)	NC score	0.027821 (rank : 867)
Query Neighborhood Hits	582	Target Neighborhood Hits	21	Shared Neighborhood Hits	17
SwissProt Accessions	Q96LR4	Gene names	FAM19A4, TAFA4
Domain Architecture	No domain graphic available
Description	Protein FAM19A4 precursor (Chemokine-like protein TAFA-4).

IER5_MOUSE
θ value	2.36792 (rank : 460)	NC score	0.023415 (rank : 882)
Query Neighborhood Hits	582	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

KRA45_HUMAN
θ value	2.36792 (rank : 461)	NC score	0.319157 (rank : 270)
Query Neighborhood Hits	582	Target Neighborhood Hits	194	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

MEP1A_HUMAN
θ value	2.36792 (rank : 462)	NC score	0.153127 (rank : 435)
Query Neighborhood Hits	582	Target Neighborhood Hits	162	Shared Neighborhood Hits	124
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MUC1_MOUSE
θ value	2.36792 (rank : 463)	NC score	0.031361 (rank : 859)
Query Neighborhood Hits	582	Target Neighborhood Hits	388	Shared Neighborhood Hits	36
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NKX26_MOUSE
θ value	2.36792 (rank : 464)	NC score	-0.006194 (rank : 944)
Query Neighborhood Hits	582	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	P43688	Gene names	Nkx2-6, Nkx-2.6, Nkx2f
Domain Architecture
Description	Homeobox protein Nkx-2.6 (Homeobox protein NK-2 homolog F).

PROC_HUMAN
θ value	2.36792 (rank : 465)	NC score	0.188411 (rank : 361)
Query Neighborhood Hits	582	Target Neighborhood Hits	406	Shared Neighborhood Hits	217
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

SRBP1_MOUSE
θ value	2.36792 (rank : 466)	NC score	0.011046 (rank : 911)
Query Neighborhood Hits	582	Target Neighborhood Hits	384	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TNR22_MOUSE
θ value	2.36792 (rank : 467)	NC score	0.127924 (rank : 478)
Query Neighborhood Hits	582	Target Neighborhood Hits	97	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR8_HUMAN
θ value	2.36792 (rank : 468)	NC score	0.106751 (rank : 530)
Query Neighborhood Hits	582	Target Neighborhood Hits	198	Shared Neighborhood Hits	86
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TS13_MOUSE
θ value	2.36792 (rank : 469)	NC score	0.018433 (rank : 892)
Query Neighborhood Hits	582	Target Neighborhood Hits	191	Shared Neighborhood Hits	10
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

VEGFC_MOUSE
θ value	2.36792 (rank : 470)	NC score	0.129318 (rank : 476)
Query Neighborhood Hits	582	Target Neighborhood Hits	119	Shared Neighborhood Hits	88
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ZN677_HUMAN
θ value	2.36792 (rank : 471)	NC score	-0.011531 (rank : 947)
Query Neighborhood Hits	582	Target Neighborhood Hits	761	Shared Neighborhood Hits	21
SwissProt Accessions	Q86XU0	Gene names	ZNF677
Domain Architecture	No domain graphic available
Description	Zinc finger protein 677.

ADA21_MOUSE
θ value	3.0926 (rank : 472)	NC score	0.114226 (rank : 511)
Query Neighborhood Hits	582	Target Neighborhood Hits	172	Shared Neighborhood Hits	123
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

BMPER_HUMAN
θ value	3.0926 (rank : 473)	NC score	0.193924 (rank : 356)
Query Neighborhood Hits	582	Target Neighborhood Hits	175	Shared Neighborhood Hits	116
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CD2L7_HUMAN
θ value	3.0926 (rank : 474)	NC score	-0.003032 (rank : 941)
Query Neighborhood Hits	582	Target Neighborhood Hits	1275	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CHRD_HUMAN
θ value	3.0926 (rank : 475)	NC score	0.104121 (rank : 537)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CO4A3_HUMAN
θ value	3.0926 (rank : 476)	NC score	0.012489 (rank : 908)
Query Neighborhood Hits	582	Target Neighborhood Hits	421	Shared Neighborhood Hits	37
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

COIA1_HUMAN
θ value	3.0926 (rank : 477)	NC score	0.017587 (rank : 895)
Query Neighborhood Hits	582	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

LRTM3_HUMAN
θ value	3.0926 (rank : 478)	NC score	0.040653 (rank : 840)
Query Neighborhood Hits	582	Target Neighborhood Hits	276	Shared Neighborhood Hits	13
SwissProt Accessions	Q86VH5, Q6N0A3	Gene names	LRRTM3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 3 precursor.

MAST4_HUMAN
θ value	3.0926 (rank : 479)	NC score	-0.006658 (rank : 945)
Query Neighborhood Hits	582	Target Neighborhood Hits	1804	Shared Neighborhood Hits	79
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MEP1A_MOUSE
θ value	3.0926 (rank : 480)	NC score	0.162779 (rank : 414)
Query Neighborhood Hits	582	Target Neighborhood Hits	166	Shared Neighborhood Hits	124
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_MOUSE
θ value	3.0926 (rank : 481)	NC score	0.115549 (rank : 509)
Query Neighborhood Hits	582	Target Neighborhood Hits	127	Shared Neighborhood Hits	84
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

NRG2_HUMAN
θ value	3.0926 (rank : 482)	NC score	0.162082 (rank : 416)
Query Neighborhood Hits	582	Target Neighborhood Hits	419	Shared Neighborhood Hits	112
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	3.0926 (rank : 483)	NC score	0.193100 (rank : 357)
Query Neighborhood Hits	582	Target Neighborhood Hits	392	Shared Neighborhood Hits	123
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

PERT_MOUSE
θ value	3.0926 (rank : 484)	NC score	0.155097 (rank : 429)
Query Neighborhood Hits	582	Target Neighborhood Hits	221	Shared Neighborhood Hits	131
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PK1L1_HUMAN
θ value	3.0926 (rank : 485)	NC score	0.008738 (rank : 918)
Query Neighborhood Hits	582	Target Neighborhood Hits	140	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

SC24C_HUMAN
θ value	3.0926 (rank : 486)	NC score	0.013677 (rank : 904)
Query Neighborhood Hits	582	Target Neighborhood Hits	662	Shared Neighborhood Hits	46
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SO1C1_MOUSE
θ value	3.0926 (rank : 487)	NC score	0.049773 (rank : 829)
Query Neighborhood Hits	582	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

TACC2_HUMAN
θ value	3.0926 (rank : 488)	NC score	0.015371 (rank : 901)
Query Neighborhood Hits	582	Target Neighborhood Hits	856	Shared Neighborhood Hits	42
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TNR16_HUMAN
θ value	3.0926 (rank : 489)	NC score	0.196959 (rank : 352)
Query Neighborhood Hits	582	Target Neighborhood Hits	183	Shared Neighborhood Hits	97
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

AAK1_MOUSE
θ value	4.03905 (rank : 490)	NC score	-0.001543 (rank : 937)
Query Neighborhood Hits	582	Target Neighborhood Hits	1051	Shared Neighborhood Hits	49
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ADA28_MOUSE
θ value	4.03905 (rank : 491)	NC score	0.123027 (rank : 488)
Query Neighborhood Hits	582	Target Neighborhood Hits	241	Shared Neighborhood Hits	159
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ATS8_MOUSE
θ value	4.03905 (rank : 492)	NC score	0.030845 (rank : 861)
Query Neighborhood Hits	582	Target Neighborhood Hits	139	Shared Neighborhood Hits	52
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

CFC1_HUMAN
θ value	4.03905 (rank : 493)	NC score	0.353691 (rank : 252)
Query Neighborhood Hits	582	Target Neighborhood Hits	148	Shared Neighborhood Hits	140
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CJ095_HUMAN
θ value	4.03905 (rank : 494)	NC score	0.060821 (rank : 700)
Query Neighborhood Hits	582	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

HHIP_HUMAN
θ value	4.03905 (rank : 495)	NC score	0.471882 (rank : 165)
Query Neighborhood Hits	582	Target Neighborhood Hits	249	Shared Neighborhood Hits	216
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

IRS1_HUMAN
θ value	4.03905 (rank : 496)	NC score	0.005491 (rank : 927)
Query Neighborhood Hits	582	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

K1802_MOUSE
θ value	4.03905 (rank : 497)	NC score	0.004612 (rank : 928)
Query Neighborhood Hits	582	Target Neighborhood Hits	1596	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KCNH3_MOUSE
θ value	4.03905 (rank : 498)	NC score	0.002808 (rank : 931)
Query Neighborhood Hits	582	Target Neighborhood Hits	133	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

LCE5A_HUMAN
θ value	4.03905 (rank : 499)	NC score	0.146316 (rank : 443)
Query Neighborhood Hits	582	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

NUFP1_HUMAN
θ value	4.03905 (rank : 500)	NC score	0.011928 (rank : 909)
Query Neighborhood Hits	582	Target Neighborhood Hits	193	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

OGFR_HUMAN
θ value	4.03905 (rank : 501)	NC score	0.016284 (rank : 899)
Query Neighborhood Hits	582	Target Neighborhood Hits	1582	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RFX2_HUMAN
θ value	4.03905 (rank : 502)	NC score	0.009482 (rank : 915)
Query Neighborhood Hits	582	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	P48378	Gene names	RFX2
Domain Architecture
Description	DNA-binding protein RFX2.

RIMB1_HUMAN
θ value	4.03905 (rank : 503)	NC score	0.006231 (rank : 923)
Query Neighborhood Hits	582	Target Neighborhood Hits	1479	Shared Neighborhood Hits	52
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SCRT1_MOUSE
θ value	4.03905 (rank : 504)	NC score	-0.013082 (rank : 950)
Query Neighborhood Hits	582	Target Neighborhood Hits	703	Shared Neighborhood Hits	11
SwissProt Accessions	Q99M85	Gene names	Scrt1
Domain Architecture	No domain graphic available
Description	Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (Scratch 1) (SCRT) (mScrt).

SETBP_HUMAN
θ value	4.03905 (rank : 505)	NC score	0.015038 (rank : 903)
Query Neighborhood Hits	582	Target Neighborhood Hits	305	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SPY1_MOUSE
θ value	4.03905 (rank : 506)	NC score	0.048003 (rank : 832)
Query Neighborhood Hits	582	Target Neighborhood Hits	57	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

ST14_HUMAN
θ value	4.03905 (rank : 507)	NC score	0.111853 (rank : 522)
Query Neighborhood Hits	582	Target Neighborhood Hits	409	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ZN184_HUMAN
θ value	4.03905 (rank : 508)	NC score	-0.011731 (rank : 948)
Query Neighborhood Hits	582	Target Neighborhood Hits	811	Shared Neighborhood Hits	24
SwissProt Accessions	Q99676, O60792, Q8TBA9	Gene names	ZNF184
Domain Architecture
Description	Zinc finger protein 184.

ZN553_MOUSE
θ value	4.03905 (rank : 509)	NC score	-0.013738 (rank : 951)
Query Neighborhood Hits	582	Target Neighborhood Hits	744	Shared Neighborhood Hits	15
SwissProt Accessions	Q3US17, Q3UFP3, Q8R0V0, Q921H7	Gene names	Znf553, Zfp553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.

BMP2K_HUMAN
θ value	5.27518 (rank : 510)	NC score	-0.005938 (rank : 943)
Query Neighborhood Hits	582	Target Neighborhood Hits	867	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CO6_HUMAN
θ value	5.27518 (rank : 511)	NC score	0.183385 (rank : 369)
Query Neighborhood Hits	582	Target Neighborhood Hits	331	Shared Neighborhood Hits	158
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CR1_HUMAN
θ value	5.27518 (rank : 512)	NC score	0.021437 (rank : 886)
Query Neighborhood Hits	582	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

DOT1L_HUMAN
θ value	5.27518 (rank : 513)	NC score	0.020670 (rank : 888)
Query Neighborhood Hits	582	Target Neighborhood Hits	660	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

EGFL8_MOUSE
θ value	5.27518 (rank : 514)	NC score	0.472506 (rank : 163)
Query Neighborhood Hits	582	Target Neighborhood Hits	266	Shared Neighborhood Hits	217
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

GP113_HUMAN
θ value	5.27518 (rank : 515)	NC score	0.073287 (rank : 625)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

KR410_HUMAN
θ value	5.27518 (rank : 516)	NC score	0.253562 (rank : 312)
Query Neighborhood Hits	582	Target Neighborhood Hits	156	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

LCE2B_HUMAN
θ value	5.27518 (rank : 517)	NC score	0.185045 (rank : 365)
Query Neighborhood Hits	582	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE3B_HUMAN
θ value	5.27518 (rank : 518)	NC score	0.118344 (rank : 504)
Query Neighborhood Hits	582	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LEUK_HUMAN
θ value	5.27518 (rank : 519)	NC score	0.027584 (rank : 868)
Query Neighborhood Hits	582	Target Neighborhood Hits	213	Shared Neighborhood Hits	25
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LRP4_HUMAN
θ value	5.27518 (rank : 520)	NC score	0.316637 (rank : 275)
Query Neighborhood Hits	582	Target Neighborhood Hits	355	Shared Neighborhood Hits	234
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRTM3_MOUSE
θ value	5.27518 (rank : 521)	NC score	0.039842 (rank : 844)
Query Neighborhood Hits	582	Target Neighborhood Hits	290	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZ81, Q3TQA3, Q8BGJ7	Gene names	Lrrtm3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 3 precursor.

LYAM2_HUMAN
θ value	5.27518 (rank : 522)	NC score	0.285448 (rank : 295)
Query Neighborhood Hits	582	Target Neighborhood Hits	394	Shared Neighborhood Hits	232
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MDC1_MOUSE
θ value	5.27518 (rank : 523)	NC score	0.031143 (rank : 860)
Query Neighborhood Hits	582	Target Neighborhood Hits	998	Shared Neighborhood Hits	72
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MLL3_HUMAN
θ value	5.27518 (rank : 524)	NC score	0.032688 (rank : 857)
Query Neighborhood Hits	582	Target Neighborhood Hits	1644	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MT3_HUMAN
θ value	5.27518 (rank : 525)	NC score	0.213117 (rank : 340)
Query Neighborhood Hits	582	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MUC13_MOUSE
θ value	5.27518 (rank : 526)	NC score	0.237119 (rank : 322)
Query Neighborhood Hits	582	Target Neighborhood Hits	447	Shared Neighborhood Hits	178
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

NCOA6_HUMAN
θ value	5.27518 (rank : 527)	NC score	0.025470 (rank : 874)
Query Neighborhood Hits	582	Target Neighborhood Hits	1202	Shared Neighborhood Hits	69
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	5.27518 (rank : 528)	NC score	0.030268 (rank : 864)
Query Neighborhood Hits	582	Target Neighborhood Hits	1076	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

OBSCN_HUMAN
θ value	5.27518 (rank : 529)	NC score	0.019257 (rank : 890)
Query Neighborhood Hits	582	Target Neighborhood Hits	1931	Shared Neighborhood Hits	82
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PAPPA_MOUSE
θ value	5.27518 (rank : 530)	NC score	0.074920 (rank : 618)
Query Neighborhood Hits	582	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PARC_HUMAN
θ value	5.27518 (rank : 531)	NC score	0.007839 (rank : 920)
Query Neighborhood Hits	582	Target Neighborhood Hits	148	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

PROP_HUMAN
θ value	5.27518 (rank : 532)	NC score	0.040884 (rank : 839)
Query Neighborhood Hits	582	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

RP1L1_MOUSE
θ value	5.27518 (rank : 533)	NC score	0.006927 (rank : 921)
Query Neighborhood Hits	582	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

RPGF1_HUMAN
θ value	5.27518 (rank : 534)	NC score	0.002539 (rank : 932)
Query Neighborhood Hits	582	Target Neighborhood Hits	262	Shared Neighborhood Hits	13
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SO1A6_MOUSE
θ value	5.27518 (rank : 535)	NC score	0.047281 (rank : 833)
Query Neighborhood Hits	582	Target Neighborhood Hits	34	Shared Neighborhood Hits	27
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

SO1C1_HUMAN
θ value	5.27518 (rank : 536)	NC score	0.046876 (rank : 834)
Query Neighborhood Hits	582	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYB5	Gene names	SLCO1C1, OATPF, SLC21A14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5).

SON_MOUSE
θ value	5.27518 (rank : 537)	NC score	0.024210 (rank : 878)
Query Neighborhood Hits	582	Target Neighborhood Hits	957	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SRRM2_MOUSE
θ value	5.27518 (rank : 538)	NC score	0.010745 (rank : 912)
Query Neighborhood Hits	582	Target Neighborhood Hits	1470	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TNR26_MOUSE
θ value	5.27518 (rank : 539)	NC score	0.081052 (rank : 593)
Query Neighborhood Hits	582	Target Neighborhood Hits	106	Shared Neighborhood Hits	58
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TRI66_MOUSE
θ value	5.27518 (rank : 540)	NC score	0.001280 (rank : 934)
Query Neighborhood Hits	582	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

UROL1_MOUSE
θ value	5.27518 (rank : 541)	NC score	0.172300 (rank : 395)
Query Neighborhood Hits	582	Target Neighborhood Hits	235	Shared Neighborhood Hits	131
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

WISP1_HUMAN
θ value	5.27518 (rank : 542)	NC score	0.062906 (rank : 684)
Query Neighborhood Hits	582	Target Neighborhood Hits	121	Shared Neighborhood Hits	58
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

ATS16_MOUSE
θ value	6.88961 (rank : 543)	NC score	0.036938 (rank : 846)
Query Neighborhood Hits	582	Target Neighborhood Hits	179	Shared Neighborhood Hits	67
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS4_MOUSE
θ value	6.88961 (rank : 544)	NC score	0.033720 (rank : 852)
Query Neighborhood Hits	582	Target Neighborhood Hits	145	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS9_HUMAN
θ value	6.88961 (rank : 545)	NC score	0.053597 (rank : 784)
Query Neighborhood Hits	582	Target Neighborhood Hits	219	Shared Neighborhood Hits	99
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

COAA1_MOUSE
θ value	6.88961 (rank : 546)	NC score	0.012523 (rank : 907)
Query Neighborhood Hits	582	Target Neighborhood Hits	286	Shared Neighborhood Hits	29
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COIA1_MOUSE
θ value	6.88961 (rank : 547)	NC score	0.012649 (rank : 905)
Query Neighborhood Hits	582	Target Neighborhood Hits	481	Shared Neighborhood Hits	42
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

ENPP2_HUMAN
θ value	6.88961 (rank : 548)	NC score	0.023005 (rank : 883)
Query Neighborhood Hits	582	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

EPHB1_HUMAN
θ value	6.88961 (rank : 549)	NC score	0.017423 (rank : 896)
Query Neighborhood Hits	582	Target Neighborhood Hits	988	Shared Neighborhood Hits	87
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

EPHB6_MOUSE
θ value	6.88961 (rank : 550)	NC score	0.023608 (rank : 880)
Query Neighborhood Hits	582	Target Neighborhood Hits	906	Shared Neighborhood Hits	71
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

F19A2_HUMAN
θ value	6.88961 (rank : 551)	NC score	0.026329 (rank : 871)
Query Neighborhood Hits	582	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N3H0, Q4G0R9, Q68DK0, Q6GTX6	Gene names	FAM19A2, TAFA2
Domain Architecture	No domain graphic available
Description	Protein FAM19A2 precursor (Chemokine-like protein TAFA-2).

F19A2_MOUSE
θ value	6.88961 (rank : 552)	NC score	0.026361 (rank : 870)
Query Neighborhood Hits	582	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TPG7, Q5M9Q3	Gene names	Fam19a2, Tafa2
Domain Architecture	No domain graphic available
Description	Protein FAM19A2 precursor (Chemokine-like protein TAFA-2).

GFRA3_MOUSE
θ value	6.88961 (rank : 553)	NC score	0.018454 (rank : 891)
Query Neighborhood Hits	582	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

LY6H_HUMAN
θ value	6.88961 (rank : 554)	NC score	0.010336 (rank : 914)
Query Neighborhood Hits	582	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O94772	Gene names	LY6H
Domain Architecture
Description	Lymphocyte antigen Ly-6H precursor.

MAVS_HUMAN
θ value	6.88961 (rank : 555)	NC score	0.017961 (rank : 894)
Query Neighborhood Hits	582	Target Neighborhood Hits	271	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MILK1_MOUSE
θ value	6.88961 (rank : 556)	NC score	0.011859 (rank : 910)
Query Neighborhood Hits	582	Target Neighborhood Hits	788	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PTN18_MOUSE
θ value	6.88961 (rank : 557)	NC score	-0.000145 (rank : 936)
Query Neighborhood Hits	582	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTPR2_MOUSE
θ value	6.88961 (rank : 558)	NC score	-0.001551 (rank : 938)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

RORG_HUMAN
θ value	6.88961 (rank : 559)	NC score	-0.001811 (rank : 939)
Query Neighborhood Hits	582	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

SEPT9_HUMAN
θ value	6.88961 (rank : 560)	NC score	0.005608 (rank : 926)
Query Neighborhood Hits	582	Target Neighborhood Hits	706	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SH23A_HUMAN
θ value	6.88961 (rank : 561)	NC score	0.004557 (rank : 929)
Query Neighborhood Hits	582	Target Neighborhood Hits	149	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BRG2, Q9Y2X4	Gene names	SH2D3A, NSP1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3A (Novel SH2-containing protein 1).

SIPA1_MOUSE
θ value	6.88961 (rank : 562)	NC score	0.001545 (rank : 933)
Query Neighborhood Hits	582	Target Neighborhood Hits	158	Shared Neighborhood Hits	4
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SMDF_HUMAN
θ value	6.88961 (rank : 563)	NC score	0.182727 (rank : 373)
Query Neighborhood Hits	582	Target Neighborhood Hits	117	Shared Neighborhood Hits	80
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SON_HUMAN
θ value	6.88961 (rank : 564)	NC score	0.024034 (rank : 879)
Query Neighborhood Hits	582	Target Neighborhood Hits	1568	Shared Neighborhood Hits	85
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SPY1_HUMAN
θ value	6.88961 (rank : 565)	NC score	0.045232 (rank : 837)
Query Neighborhood Hits	582	Target Neighborhood Hits	64	Shared Neighborhood Hits	42
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

UPK3A_MOUSE
θ value	6.88961 (rank : 566)	NC score	0.009074 (rank : 917)
Query Neighborhood Hits	582	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKX8	Gene names	Upk3a, Upk3
Domain Architecture	No domain graphic available
Description	Uroplakin-3A precursor (Uroplakin III) (UPIII).

BSN_HUMAN
θ value	8.99809 (rank : 567)	NC score	0.015618 (rank : 900)
Query Neighborhood Hits	582	Target Neighborhood Hits	1537	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

C163A_MOUSE
θ value	8.99809 (rank : 568)	NC score	0.006059 (rank : 925)
Query Neighborhood Hits	582	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q2VLH6, Q2VLH5, Q99MX8	Gene names	Cd163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) [Contains: Soluble CD163 (sCD163)].

CFC1_MOUSE
θ value	8.99809 (rank : 569)	NC score	0.316232 (rank : 276)
Query Neighborhood Hits	582	Target Neighborhood Hits	125	Shared Neighborhood Hits	122
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CO9_HUMAN
θ value	8.99809 (rank : 570)	NC score	0.119773 (rank : 499)
Query Neighborhood Hits	582	Target Neighborhood Hits	147	Shared Neighborhood Hits	87
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

ENPP2_MOUSE
θ value	8.99809 (rank : 571)	NC score	0.028858 (rank : 866)
Query Neighborhood Hits	582	Target Neighborhood Hits	66	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

HYAL3_MOUSE
θ value	8.99809 (rank : 572)	NC score	0.035818 (rank : 848)
Query Neighborhood Hits	582	Target Neighborhood Hits	44	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

KSYK_MOUSE
θ value	8.99809 (rank : 573)	NC score	-0.001908 (rank : 940)
Query Neighborhood Hits	582	Target Neighborhood Hits	944	Shared Neighborhood Hits	28
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LYAM1_MOUSE
θ value	8.99809 (rank : 574)	NC score	0.239603 (rank : 318)
Query Neighborhood Hits	582	Target Neighborhood Hits	332	Shared Neighborhood Hits	188
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MT4_HUMAN
θ value	8.99809 (rank : 575)	NC score	0.145115 (rank : 445)
Query Neighborhood Hits	582	Target Neighborhood Hits	83	Shared Neighborhood Hits	59
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MTSS1_HUMAN
θ value	8.99809 (rank : 576)	NC score	0.015295 (rank : 902)
Query Neighborhood Hits	582	Target Neighborhood Hits	504	Shared Neighborhood Hits	33
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

NEU2_HUMAN
θ value	8.99809 (rank : 577)	NC score	0.033496 (rank : 854)
Query Neighborhood Hits	582	Target Neighborhood Hits	37	Shared Neighborhood Hits	30
SwissProt Accessions	P01185, O14935	Gene names	AVP, ARVP, VP
Domain Architecture
Description	Vasopressin-neurophysin 2-copeptin precursor (AVP-NPII) [Contains: Arg-vasopressin; Neurophysin 2 (Neurophysin-II); Copeptin].

NUP98_HUMAN
θ value	8.99809 (rank : 578)	NC score	0.006224 (rank : 924)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	P52948, Q8IUT2, Q8WYB0, Q96E54, Q9H3Q4, Q9NT02, Q9UF57, Q9UHX0, Q9Y6J4, Q9Y6J5	Gene names	NUP98
Domain Architecture
Description	Nuclear pore complex protein Nup98-Nup96 precursor [Contains: Nuclear pore complex protein Nup98 (Nucleoporin Nup98) (98 kDa nucleoporin); Nuclear pore complex protein Nup96 (Nucleoporin Nup96) (96 kDa nucleoporin)].

SIRT1_HUMAN
θ value	8.99809 (rank : 579)	NC score	0.002812 (rank : 930)
Query Neighborhood Hits	582	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q96EB6, Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0	Gene names	SIRT1, SIR2L1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (hSIRT1) (hSIR2) (SIR2-like protein 1).

TNR7_MOUSE
θ value	8.99809 (rank : 580)	NC score	0.090522 (rank : 560)
Query Neighborhood Hits	582	Target Neighborhood Hits	112	Shared Neighborhood Hits	54
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

UPK3A_HUMAN
θ value	8.99809 (rank : 581)	NC score	0.008138 (rank : 919)
Query Neighborhood Hits	582	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O75631, O60261	Gene names	UPK3A, UPK3
Domain Architecture	No domain graphic available
Description	Uroplakin-3A precursor (Uroplakin III) (UPIII).

ZN687_MOUSE
θ value	8.99809 (rank : 582)	NC score	-0.008747 (rank : 946)
Query Neighborhood Hits	582	Target Neighborhood Hits	913	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ADA17_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.121897 (rank : 490)
Query Neighborhood Hits	582	Target Neighborhood Hits	223	Shared Neighborhood Hits	140
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA18_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.113326 (rank : 515)
Query Neighborhood Hits	582	Target Neighborhood Hits	184	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA19_MOUSE
θ value	θ > 10 (rank : 585)	NC score	0.144267 (rank : 448)
Query Neighborhood Hits	582	Target Neighborhood Hits	315	Shared Neighborhood Hits	196
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA20_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.081899 (rank : 590)
Query Neighborhood Hits	582	Target Neighborhood Hits	143	Shared Neighborhood Hits	90
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA21_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.106900 (rank : 528)
Query Neighborhood Hits	582	Target Neighborhood Hits	181	Shared Neighborhood Hits	130
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA23_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.151306 (rank : 438)
Query Neighborhood Hits	582	Target Neighborhood Hits	235	Shared Neighborhood Hits	172
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.146943 (rank : 441)
Query Neighborhood Hits	582	Target Neighborhood Hits	245	Shared Neighborhood Hits	183
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA25_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.118468 (rank : 502)
Query Neighborhood Hits	582	Target Neighborhood Hits	213	Shared Neighborhood Hits	151
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA33_MOUSE
θ value	θ > 10 (rank : 591)	NC score	0.132796 (rank : 470)
Query Neighborhood Hits	582	Target Neighborhood Hits	231	Shared Neighborhood Hits	161
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.104391 (rank : 536)
Query Neighborhood Hits	582	Target Neighborhood Hits	175	Shared Neighborhood Hits	124
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM7_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.131525 (rank : 473)
Query Neighborhood Hits	582	Target Neighborhood Hits	221	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.112552 (rank : 519)
Query Neighborhood Hits	582	Target Neighborhood Hits	200	Shared Neighborhood Hits	139
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADEC1_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.052361 (rank : 801)
Query Neighborhood Hits	582	Target Neighborhood Hits	80	Shared Neighborhood Hits	35
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.053547 (rank : 786)
Query Neighborhood Hits	582	Target Neighborhood Hits	85	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADM1A_MOUSE
θ value	θ > 10 (rank : 597)	NC score	0.118992 (rank : 501)
Query Neighborhood Hits	582	Target Neighborhood Hits	230	Shared Neighborhood Hits	165
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADM1B_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.104420 (rank : 535)
Query Neighborhood Hits	582	Target Neighborhood Hits	236	Shared Neighborhood Hits	139
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

AMGO3_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.054273 (rank : 769)
Query Neighborhood Hits	582	Target Neighborhood Hits	276	Shared Neighborhood Hits	16
SwissProt Accessions	Q86WK7, Q96JH6	Gene names	AMIGO3, ALI3, KIAA1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

APR3_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.111987 (rank : 521)
Query Neighborhood Hits	582	Target Neighborhood Hits	50	Shared Neighborhood Hits	47
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

APR3_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.136686 (rank : 464)
Query Neighborhood Hits	582	Target Neighborhood Hits	61	Shared Neighborhood Hits	55
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

AREG_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.056454 (rank : 740)
Query Neighborhood Hits	582	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	P15514	Gene names	AREG
Domain Architecture	No domain graphic available
Description	Amphiregulin precursor (AR) (Colorectum cell-derived growth factor) (CRDGF).

ASTN_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.081780 (rank : 591)
Query Neighborhood Hits	582	Target Neighborhood Hits	105	Shared Neighborhood Hits	71
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.082350 (rank : 587)
Query Neighborhood Hits	582	Target Neighborhood Hits	98	Shared Neighborhood Hits	68
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

BAI1_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.090336 (rank : 561)
Query Neighborhood Hits	582	Target Neighborhood Hits	375	Shared Neighborhood Hits	78
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.084575 (rank : 579)
Query Neighborhood Hits	582	Target Neighborhood Hits	340	Shared Neighborhood Hits	69
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.073743 (rank : 621)
Query Neighborhood Hits	582	Target Neighborhood Hits	332	Shared Neighborhood Hits	55
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	θ > 10 (rank : 608)	NC score	0.075118 (rank : 617)
Query Neighborhood Hits	582	Target Neighborhood Hits	323	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.079715 (rank : 597)
Query Neighborhood Hits	582	Target Neighborhood Hits	246	Shared Neighborhood Hits	57
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	θ > 10 (rank : 610)	NC score	0.081545 (rank : 592)
Query Neighborhood Hits	582	Target Neighborhood Hits	250	Shared Neighborhood Hits	61
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BMP1_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.121791 (rank : 491)
Query Neighborhood Hits	582	Target Neighborhood Hits	233	Shared Neighborhood Hits	144
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 612)	NC score	0.123182 (rank : 487)
Query Neighborhood Hits	582	Target Neighborhood Hits	236	Shared Neighborhood Hits	145
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMPER_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.210083 (rank : 344)
Query Neighborhood Hits	582	Target Neighborhood Hits	194	Shared Neighborhood Hits	139
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BTC_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.102993 (rank : 539)
Query Neighborhood Hits	582	Target Neighborhood Hits	70	Shared Neighborhood Hits	47
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

BTC_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.123685 (rank : 485)
Query Neighborhood Hits	582	Target Neighborhood Hits	67	Shared Neighborhood Hits	47
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

C1RA_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.084006 (rank : 581)
Query Neighborhood Hits	582	Target Neighborhood Hits	379	Shared Neighborhood Hits	137
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.082578 (rank : 585)
Query Neighborhood Hits	582	Target Neighborhood Hits	380	Shared Neighborhood Hits	136
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.070891 (rank : 637)
Query Neighborhood Hits	582	Target Neighborhood Hits	364	Shared Neighborhood Hits	125
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.067408 (rank : 658)
Query Neighborhood Hits	582	Target Neighborhood Hits	359	Shared Neighborhood Hits	126
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CAD13_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.050861 (rank : 816)
Query Neighborhood Hits	582	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	P55290, Q8TBX3	Gene names	CDH13, CDHH
Domain Architecture
Description	Cadherin-13 precursor (Truncated-cadherin) (T-cadherin) (T-cad) (Heart-cadherin) (H-cadherin) (P105).

CAD13_MOUSE
θ value	θ > 10 (rank : 621)	NC score	0.050724 (rank : 820)
Query Neighborhood Hits	582	Target Neighborhood Hits	156	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTR5	Gene names	Cdh13
Domain Architecture
Description	Cadherin-13 precursor (Truncated-cadherin) (T-cadherin) (T-cad) (Heart-cadherin) (H-cadherin).

CAD16_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.056690 (rank : 736)
Query Neighborhood Hits	582	Target Neighborhood Hits	159	Shared Neighborhood Hits	10
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

CAD16_MOUSE
θ value	θ > 10 (rank : 623)	NC score	0.056147 (rank : 749)
Query Neighborhood Hits	582	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	O88338, Q9JLZ5	Gene names	Cdh16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

CAD17_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.058547 (rank : 724)
Query Neighborhood Hits	582	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	Q12864, Q15336	Gene names	CDH17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (Intestinal peptide-associated transporter HPT-1).

CAD17_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.060367 (rank : 704)
Query Neighborhood Hits	582	Target Neighborhood Hits	157	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

CAD23_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.075750 (rank : 615)
Query Neighborhood Hits	582	Target Neighborhood Hits	197	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_MOUSE
θ value	θ > 10 (rank : 627)	NC score	0.076024 (rank : 613)
Query Neighborhood Hits	582	Target Neighborhood Hits	208	Shared Neighborhood Hits	17
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CD2A1_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.051925 (rank : 809)
Query Neighborhood Hits	582	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CD320_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.132265 (rank : 471)
Query Neighborhood Hits	582	Target Neighborhood Hits	103	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD97_MOUSE
θ value	θ > 10 (rank : 630)	NC score	0.326917 (rank : 263)
Query Neighborhood Hits	582	Target Neighborhood Hits	295	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CDN2B_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.052263 (rank : 802)
Query Neighborhood Hits	582	Target Neighborhood Hits	196	Shared Neighborhood Hits	10
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CHRD_MOUSE
θ value	θ > 10 (rank : 632)	NC score	0.099065 (rank : 546)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CLC14_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.131463 (rank : 474)
Query Neighborhood Hits	582	Target Neighborhood Hits	143	Shared Neighborhood Hits	95
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 634)	NC score	0.138045 (rank : 461)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.105507 (rank : 532)
Query Neighborhood Hits	582	Target Neighborhood Hits	200	Shared Neighborhood Hits	102
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.096976 (rank : 550)
Query Neighborhood Hits	582	Target Neighborhood Hits	182	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	θ > 10 (rank : 637)	NC score	0.104734 (rank : 534)
Query Neighborhood Hits	582	Target Neighborhood Hits	199	Shared Neighborhood Hits	92
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

COCA1_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.052492 (rank : 800)
Query Neighborhood Hits	582	Target Neighborhood Hits	467	Shared Neighborhood Hits	53
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

CORIN_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.159265 (rank : 422)
Query Neighborhood Hits	582	Target Neighborhood Hits	453	Shared Neighborhood Hits	206
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CRAC1_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.138162 (rank : 460)
Query Neighborhood Hits	582	Target Neighborhood Hits	111	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 641)	NC score	0.140003 (rank : 456)
Query Neighborhood Hits	582	Target Neighborhood Hits	112	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRDL1_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.056301 (rank : 744)
Query Neighborhood Hits	582	Target Neighborhood Hits	75	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.058435 (rank : 725)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.067295 (rank : 659)
Query Neighborhood Hits	582	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 645)	NC score	0.070937 (rank : 636)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CS1A_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.070980 (rank : 635)
Query Neighborhood Hits	582	Target Neighborhood Hits	360	Shared Neighborhood Hits	120
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 647)	NC score	0.070794 (rank : 639)
Query Neighborhood Hits	582	Target Neighborhood Hits	361	Shared Neighborhood Hits	120
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CT075_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.051704 (rank : 810)
Query Neighborhood Hits	582	Target Neighborhood Hits	387	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

CT075_MOUSE
θ value	θ > 10 (rank : 649)	NC score	0.050807 (rank : 818)
Query Neighborhood Hits	582	Target Neighborhood Hits	358	Shared Neighborhood Hits	29
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

CT127_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.117092 (rank : 506)
Query Neighborhood Hits	582	Target Neighborhood Hits	67	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CYR61_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.102321 (rank : 540)
Query Neighborhood Hits	582	Target Neighborhood Hits	159	Shared Neighborhood Hits	85
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 652)	NC score	0.107157 (rank : 527)
Query Neighborhood Hits	582	Target Neighborhood Hits	156	Shared Neighborhood Hits	82
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DCBD1_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.070378 (rank : 641)
Query Neighborhood Hits	582	Target Neighborhood Hits	110	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.068180 (rank : 654)
Query Neighborhood Hits	582	Target Neighborhood Hits	118	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.069045 (rank : 650)
Query Neighborhood Hits	582	Target Neighborhood Hits	113	Shared Neighborhood Hits	23
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DCC_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.055976 (rank : 751)
Query Neighborhood Hits	582	Target Neighborhood Hits	583	Shared Neighborhood Hits	53
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCC_MOUSE
θ value	θ > 10 (rank : 657)	NC score	0.056853 (rank : 735)
Query Neighborhood Hits	582	Target Neighborhood Hits	896	Shared Neighborhood Hits	68
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DKK3_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.078905 (rank : 599)
Query Neighborhood Hits	582	Target Neighborhood Hits	74	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
θ value	θ > 10 (rank : 659)	NC score	0.092768 (rank : 557)
Query Neighborhood Hits	582	Target Neighborhood Hits	83	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

DSCAM_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.060191 (rank : 709)
Query Neighborhood Hits	582	Target Neighborhood Hits	524	Shared Neighborhood Hits	42
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.061413 (rank : 693)
Query Neighborhood Hits	582	Target Neighborhood Hits	589	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

ECM2_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.060880 (rank : 699)
Query Neighborhood Hits	582	Target Neighborhood Hits	402	Shared Neighborhood Hits	46
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

ELTD1_MOUSE
θ value	θ > 10 (rank : 663)	NC score	0.335817 (rank : 261)
Query Neighborhood Hits	582	Target Neighborhood Hits	288	Shared Neighborhood Hits	183
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR3_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.201036 (rank : 348)
Query Neighborhood Hits	582	Target Neighborhood Hits	245	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 665)	NC score	0.151802 (rank : 437)
Query Neighborhood Hits	582	Target Neighborhood Hits	191	Shared Neighborhood Hits	103
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

EPGN_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.106301 (rank : 531)
Query Neighborhood Hits	582	Target Neighborhood Hits	59	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EREG_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.153492 (rank : 434)
Query Neighborhood Hits	582	Target Neighborhood Hits	73	Shared Neighborhood Hits	53
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

EREG_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.106790 (rank : 529)
Query Neighborhood Hits	582	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ESM1_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.262043 (rank : 308)
Query Neighborhood Hits	582	Target Neighborhood Hits	110	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA5_HUMAN
θ value	θ > 10 (rank : 670)	NC score	0.073645 (rank : 623)
Query Neighborhood Hits	582	Target Neighborhood Hits	172	Shared Neighborhood Hits	24
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

FA8_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.064335 (rank : 677)
Query Neighborhood Hits	582	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
θ value	θ > 10 (rank : 672)	NC score	0.064007 (rank : 678)
Query Neighborhood Hits	582	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FINC_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.080242 (rank : 596)
Query Neighborhood Hits	582	Target Neighborhood Hits	302	Shared Neighborhood Hits	62
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 674)	NC score	0.080632 (rank : 594)
Query Neighborhood Hits	582	Target Neighborhood Hits	309	Shared Neighborhood Hits	69
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FREM1_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.050860 (rank : 817)
Query Neighborhood Hits	582	Target Neighborhood Hits	170	Shared Neighborhood Hits	19
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM1_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.050159 (rank : 826)
Query Neighborhood Hits	582	Target Neighborhood Hits	163	Shared Neighborhood Hits	18
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

GLPC_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.078832 (rank : 600)
Query Neighborhood Hits	582	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P04921, Q92642	Gene names	GYPC, GPC
Domain Architecture
Description	Glycophorin C (PAS-2') (Glycoprotein beta) (GLPC) (Glycoconnectin) (Sialoglycoprotein D) (Glycophorin D) (GPD) (CD236 antigen).

GNPTA_HUMAN
θ value	θ > 10 (rank : 678)	NC score	0.066860 (rank : 663)
Query Neighborhood Hits	582	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GNPTA_MOUSE
θ value	θ > 10 (rank : 679)	NC score	0.066357 (rank : 666)
Query Neighborhood Hits	582	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GP110_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.053100 (rank : 790)
Query Neighborhood Hits	582	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP110_MOUSE
θ value	θ > 10 (rank : 681)	NC score	0.053878 (rank : 781)
Query Neighborhood Hits	582	Target Neighborhood Hits	92	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP112_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.076999 (rank : 610)
Query Neighborhood Hits	582	Target Neighborhood Hits	441	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP114_HUMAN
θ value	θ > 10 (rank : 683)	NC score	0.065100 (rank : 675)
Query Neighborhood Hits	582	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP115_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.055691 (rank : 752)
Query Neighborhood Hits	582	Target Neighborhood Hits	87	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GP115_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.058091 (rank : 730)
Query Neighborhood Hits	582	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GP116_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.078158 (rank : 603)
Query Neighborhood Hits	582	Target Neighborhood Hits	167	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP124_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.086676 (rank : 574)
Query Neighborhood Hits	582	Target Neighborhood Hits	304	Shared Neighborhood Hits	24
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP124_MOUSE
θ value	θ > 10 (rank : 688)	NC score	0.086236 (rank : 577)
Query Neighborhood Hits	582	Target Neighborhood Hits	423	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_HUMAN
θ value	θ > 10 (rank : 689)	NC score	0.088874 (rank : 569)
Query Neighborhood Hits	582	Target Neighborhood Hits	327	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP125_MOUSE
θ value	θ > 10 (rank : 690)	NC score	0.083602 (rank : 583)
Query Neighborhood Hits	582	Target Neighborhood Hits	329	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP126_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.059788 (rank : 713)
Query Neighborhood Hits	582	Target Neighborhood Hits	187	Shared Neighborhood Hits	23
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP128_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.088960 (rank : 567)
Query Neighborhood Hits	582	Target Neighborhood Hits	135	Shared Neighborhood Hits	43
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP128_MOUSE
θ value	θ > 10 (rank : 693)	NC score	0.094070 (rank : 554)
Query Neighborhood Hits	582	Target Neighborhood Hits	141	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP133_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.077657 (rank : 606)
Query Neighborhood Hits	582	Target Neighborhood Hits	115	Shared Neighborhood Hits	15
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP144_HUMAN
θ value	θ > 10 (rank : 695)	NC score	0.082049 (rank : 589)
Query Neighborhood Hits	582	Target Neighborhood Hits	108	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GP1BB_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.056644 (rank : 737)
Query Neighborhood Hits	582	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	P13224, Q8NG40	Gene names	GP1BB
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (Antigen CD42b-beta) (CD42c antigen).

GP1BB_MOUSE
θ value	θ > 10 (rank : 697)	NC score	0.055174 (rank : 760)
Query Neighborhood Hits	582	Target Neighborhood Hits	136	Shared Neighborhood Hits	10
SwissProt Accessions	P56400	Gene names	Gp1bb
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (CD42c antigen).

GPIX_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.061799 (rank : 690)
Query Neighborhood Hits	582	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	P14770, Q14445, Q92525	Gene names	GP9
Domain Architecture
Description	Platelet glycoprotein IX precursor (GPIX) (CD42a antigen).

GPR56_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.062509 (rank : 687)
Query Neighborhood Hits	582	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GPR56_MOUSE
θ value	θ > 10 (rank : 700)	NC score	0.060321 (rank : 705)
Query Neighborhood Hits	582	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

GPR64_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.069814 (rank : 643)
Query Neighborhood Hits	582	Target Neighborhood Hits	207	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GPR64_MOUSE
θ value	θ > 10 (rank : 702)	NC score	0.069371 (rank : 647)
Query Neighborhood Hits	582	Target Neighborhood Hits	156	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR97_MOUSE
θ value	θ > 10 (rank : 703)	NC score	0.059178 (rank : 720)
Query Neighborhood Hits	582	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

GPR98_HUMAN
θ value	θ > 10 (rank : 704)	NC score	0.070553 (rank : 640)
Query Neighborhood Hits	582	Target Neighborhood Hits	202	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GPR98_MOUSE
θ value	θ > 10 (rank : 705)	NC score	0.063100 (rank : 682)
Query Neighborhood Hits	582	Target Neighborhood Hits	206	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

HBEGF_HUMAN
θ value	θ > 10 (rank : 706)	NC score	0.097173 (rank : 549)
Query Neighborhood Hits	582	Target Neighborhood Hits	61	Shared Neighborhood Hits	43
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

HBEGF_MOUSE
θ value	θ > 10 (rank : 707)	NC score	0.073352 (rank : 624)
Query Neighborhood Hits	582	Target Neighborhood Hits	48	Shared Neighborhood Hits	32
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

HG2A_HUMAN
θ value	θ > 10 (rank : 708)	NC score	0.060487 (rank : 703)
Query Neighborhood Hits	582	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

HG2A_MOUSE
θ value	θ > 10 (rank : 709)	NC score	0.064491 (rank : 676)
Query Neighborhood Hits	582	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

HHIP_MOUSE
θ value	θ > 10 (rank : 710)	NC score	0.442902 (rank : 195)
Query Neighborhood Hits	582	Target Neighborhood Hits	219	Shared Neighborhood Hits	194
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HPLN1_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.054227 (rank : 773)
Query Neighborhood Hits	582	Target Neighborhood Hits	67	Shared Neighborhood Hits	12
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN1_MOUSE
θ value	θ > 10 (rank : 712)	NC score	0.054294 (rank : 767)
Query Neighborhood Hits	582	Target Neighborhood Hits	64	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN2_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.061394 (rank : 694)
Query Neighborhood Hits	582	Target Neighborhood Hits	80	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN2_MOUSE
θ value	θ > 10 (rank : 714)	NC score	0.062832 (rank : 686)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN3_HUMAN
θ value	θ > 10 (rank : 715)	NC score	0.055278 (rank : 758)
Query Neighborhood Hits	582	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

HPLN3_MOUSE
θ value	θ > 10 (rank : 716)	NC score	0.056282 (rank : 746)
Query Neighborhood Hits	582	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

HPLN4_HUMAN
θ value	θ > 10 (rank : 717)	NC score	0.056051 (rank : 750)
Query Neighborhood Hits	582	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

HPLN4_MOUSE
θ value	θ > 10 (rank : 718)	NC score	0.057402 (rank : 732)
Query Neighborhood Hits	582	Target Neighborhood Hits	98	Shared Neighborhood Hits	14
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

IBP1_MOUSE
θ value	θ > 10 (rank : 719)	NC score	0.052029 (rank : 806)
Query Neighborhood Hits	582	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP3_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.056412 (rank : 741)
Query Neighborhood Hits	582	Target Neighborhood Hits	67	Shared Neighborhood Hits	31
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IDD_HUMAN
θ value	θ > 10 (rank : 721)	NC score	0.069225 (rank : 649)
Query Neighborhood Hits	582	Target Neighborhood Hits	127	Shared Neighborhood Hits	45
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

IDD_MOUSE
θ value	θ > 10 (rank : 722)	NC score	0.065696 (rank : 670)
Query Neighborhood Hits	582	Target Neighborhood Hits	151	Shared Neighborhood Hits	45
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

KR111_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.113896 (rank : 513)
Query Neighborhood Hits	582	Target Neighborhood Hits	90	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

KR121_HUMAN
θ value	θ > 10 (rank : 724)	NC score	0.054367 (rank : 766)
Query Neighborhood Hits	582	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P59990	Gene names	KRTAP12-1, KAP12.1, KRTAP12.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-1 (Keratin-associated protein 12.1) (High sulfur keratin-associated protein 12.1).

KR123_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.115294 (rank : 510)
Query Neighborhood Hits	582	Target Neighborhood Hits	75	Shared Neighborhood Hits	50
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

KR124_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.163827 (rank : 411)
Query Neighborhood Hits	582	Target Neighborhood Hits	124	Shared Neighborhood Hits	84
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR131_HUMAN
θ value	θ > 10 (rank : 727)	NC score	0.093452 (rank : 556)
Query Neighborhood Hits	582	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

KR132_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.075255 (rank : 616)
Query Neighborhood Hits	582	Target Neighborhood Hits	69	Shared Neighborhood Hits	46
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

KR133_HUMAN
θ value	θ > 10 (rank : 729)	NC score	0.083858 (rank : 582)
Query Neighborhood Hits	582	Target Neighborhood Hits	66	Shared Neighborhood Hits	49
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

KR134_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.089580 (rank : 563)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	49
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

KR241_HUMAN
θ value	θ > 10 (rank : 731)	NC score	0.122439 (rank : 489)
Query Neighborhood Hits	582	Target Neighborhood Hits	71	Shared Neighborhood Hits	51
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

KR261_HUMAN
θ value	θ > 10 (rank : 732)	NC score	0.089155 (rank : 564)
Query Neighborhood Hits	582	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

KR412_HUMAN
θ value	θ > 10 (rank : 733)	NC score	0.285071 (rank : 296)
Query Neighborhood Hits	582	Target Neighborhood Hits	178	Shared Neighborhood Hits	128
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR413_HUMAN
θ value	θ > 10 (rank : 734)	NC score	0.154825 (rank : 432)
Query Neighborhood Hits	582	Target Neighborhood Hits	112	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KRA93_HUMAN
θ value	θ > 10 (rank : 735)	NC score	0.303664 (rank : 286)
Query Neighborhood Hits	582	Target Neighborhood Hits	203	Shared Neighborhood Hits	142
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA98_HUMAN
θ value	θ > 10 (rank : 736)	NC score	0.296743 (rank : 289)
Query Neighborhood Hits	582	Target Neighborhood Hits	185	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 737)	NC score	0.255932 (rank : 310)
Query Neighborhood Hits	582	Target Neighborhood Hits	173	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

L1CAM_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.050775 (rank : 819)
Query Neighborhood Hits	582	Target Neighborhood Hits	457	Shared Neighborhood Hits	43
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

L1CAM_MOUSE
θ value	θ > 10 (rank : 739)	NC score	0.050657 (rank : 821)
Query Neighborhood Hits	582	Target Neighborhood Hits	457	Shared Neighborhood Hits	41
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

LCE1A_HUMAN
θ value	θ > 10 (rank : 740)	NC score	0.237800 (rank : 321)
Query Neighborhood Hits	582	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.293252 (rank : 292)
Query Neighborhood Hits	582	Target Neighborhood Hits	58	Shared Neighborhood Hits	49
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 742)	NC score	0.304293 (rank : 285)
Query Neighborhood Hits	582	Target Neighborhood Hits	65	Shared Neighborhood Hits	52
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.243682 (rank : 317)
Query Neighborhood Hits	582	Target Neighborhood Hits	44	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 744)	NC score	0.250885 (rank : 313)
Query Neighborhood Hits	582	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.238426 (rank : 320)
Query Neighborhood Hits	582	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2C_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.182428 (rank : 375)
Query Neighborhood Hits	582	Target Neighborhood Hits	53	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 747)	NC score	0.180301 (rank : 378)
Query Neighborhood Hits	582	Target Neighborhood Hits	50	Shared Neighborhood Hits	35
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.195704 (rank : 353)
Query Neighborhood Hits	582	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3C_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.066509 (rank : 665)
Query Neighborhood Hits	582	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

LCE4A_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.162780 (rank : 413)
Query Neighborhood Hits	582	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LORI_MOUSE
θ value	θ > 10 (rank : 751)	NC score	0.113804 (rank : 514)
Query Neighborhood Hits	582	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LPHN1_HUMAN
θ value	θ > 10 (rank : 752)	NC score	0.070871 (rank : 638)
Query Neighborhood Hits	582	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.071006 (rank : 634)
Query Neighborhood Hits	582	Target Neighborhood Hits	136	Shared Neighborhood Hits	17
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LPHN3_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.069640 (rank : 644)
Query Neighborhood Hits	582	Target Neighborhood Hits	139	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LRC17_HUMAN
θ value	θ > 10 (rank : 755)	NC score	0.059063 (rank : 723)
Query Neighborhood Hits	582	Target Neighborhood Hits	267	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N6Y2, Q13288, Q6UWA7, Q75MG5	Gene names	LRRC17, P37NB
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor (p37NB).

LRC17_MOUSE
θ value	θ > 10 (rank : 756)	NC score	0.059795 (rank : 712)
Query Neighborhood Hits	582	Target Neighborhood Hits	268	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CXD9	Gene names	Lrrc17
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor.

LRC21_HUMAN
θ value	θ > 10 (rank : 757)	NC score	0.084259 (rank : 580)
Query Neighborhood Hits	582	Target Neighborhood Hits	456	Shared Neighborhood Hits	32
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC21_MOUSE
θ value	θ > 10 (rank : 758)	NC score	0.080384 (rank : 595)
Query Neighborhood Hits	582	Target Neighborhood Hits	462	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC24_HUMAN
θ value	θ > 10 (rank : 759)	NC score	0.071490 (rank : 633)
Query Neighborhood Hits	582	Target Neighborhood Hits	404	Shared Neighborhood Hits	27
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC24_MOUSE
θ value	θ > 10 (rank : 760)	NC score	0.068201 (rank : 653)
Query Neighborhood Hits	582	Target Neighborhood Hits	387	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC3B_HUMAN
θ value	θ > 10 (rank : 761)	NC score	0.052250 (rank : 803)
Query Neighborhood Hits	582	Target Neighborhood Hits	215	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PB8	Gene names	LRRC3B, LRP15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

LRC3B_MOUSE
θ value	θ > 10 (rank : 762)	NC score	0.052238 (rank : 804)
Query Neighborhood Hits	582	Target Neighborhood Hits	215	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VCH9	Gene names	Lrrc3b, Lrp15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

LRC52_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.054680 (rank : 763)
Query Neighborhood Hits	582	Target Neighborhood Hits	229	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N7C0, Q5T9K5	Gene names	LRRC52
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 52 precursor.

LRC52_MOUSE
θ value	θ > 10 (rank : 764)	NC score	0.050154 (rank : 827)
Query Neighborhood Hits	582	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q5M8M9	Gene names	Lrrc52
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 52 precursor.

LRC55_HUMAN
θ value	θ > 10 (rank : 765)	NC score	0.053236 (rank : 787)
Query Neighborhood Hits	582	Target Neighborhood Hits	257	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZSA7	Gene names	LRRC55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

LRC55_MOUSE
θ value	θ > 10 (rank : 766)	NC score	0.054155 (rank : 774)
Query Neighborhood Hits	582	Target Neighborhood Hits	254	Shared Neighborhood Hits	10
SwissProt Accessions	Q3UY51	Gene names	Lrrc55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

LRFN2_HUMAN
θ value	θ > 10 (rank : 767)	NC score	0.056347 (rank : 742)
Query Neighborhood Hits	582	Target Neighborhood Hits	450	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN2_MOUSE
θ value	θ > 10 (rank : 768)	NC score	0.053570 (rank : 785)
Query Neighborhood Hits	582	Target Neighborhood Hits	450	Shared Neighborhood Hits	23
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN3_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.053651 (rank : 783)
Query Neighborhood Hits	582	Target Neighborhood Hits	444	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN3_MOUSE
θ value	θ > 10 (rank : 770)	NC score	0.055022 (rank : 761)
Query Neighborhood Hits	582	Target Neighborhood Hits	455	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN4_HUMAN
θ value	θ > 10 (rank : 771)	NC score	0.056320 (rank : 743)
Query Neighborhood Hits	582	Target Neighborhood Hits	462	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN4_MOUSE
θ value	θ > 10 (rank : 772)	NC score	0.054667 (rank : 764)
Query Neighborhood Hits	582	Target Neighborhood Hits	442	Shared Neighborhood Hits	29
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN5_HUMAN
θ value	θ > 10 (rank : 773)	NC score	0.054265 (rank : 770)
Query Neighborhood Hits	582	Target Neighborhood Hits	464	Shared Neighborhood Hits	22
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRFN5_MOUSE
θ value	θ > 10 (rank : 774)	NC score	0.054817 (rank : 762)
Query Neighborhood Hits	582	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRIG1_HUMAN
θ value	θ > 10 (rank : 775)	NC score	0.065152 (rank : 674)
Query Neighborhood Hits	582	Target Neighborhood Hits	654	Shared Neighborhood Hits	27
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG1_MOUSE
θ value	θ > 10 (rank : 776)	NC score	0.065480 (rank : 672)
Query Neighborhood Hits	582	Target Neighborhood Hits	627	Shared Neighborhood Hits	30
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG2_HUMAN
θ value	θ > 10 (rank : 777)	NC score	0.059283 (rank : 718)
Query Neighborhood Hits	582	Target Neighborhood Hits	595	Shared Neighborhood Hits	28
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG2_MOUSE
θ value	θ > 10 (rank : 778)	NC score	0.060694 (rank : 702)
Query Neighborhood Hits	582	Target Neighborhood Hits	586	Shared Neighborhood Hits	28
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG3_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.059917 (rank : 711)
Query Neighborhood Hits	582	Target Neighborhood Hits	601	Shared Neighborhood Hits	30
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LRIG3_MOUSE
θ value	θ > 10 (rank : 780)	NC score	0.060918 (rank : 698)
Query Neighborhood Hits	582	Target Neighborhood Hits	611	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

LRP10_HUMAN
θ value	θ > 10 (rank : 781)	NC score	0.138592 (rank : 459)
Query Neighborhood Hits	582	Target Neighborhood Hits	197	Shared Neighborhood Hits	89
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 782)	NC score	0.098694 (rank : 547)
Query Neighborhood Hits	582	Target Neighborhood Hits	205	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 783)	NC score	0.098146 (rank : 548)
Query Neighborhood Hits	582	Target Neighborhood Hits	180	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 784)	NC score	0.135487 (rank : 465)
Query Neighborhood Hits	582	Target Neighborhood Hits	280	Shared Neighborhood Hits	115
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP4_MOUSE
θ value	θ > 10 (rank : 785)	NC score	0.317685 (rank : 272)
Query Neighborhood Hits	582	Target Neighborhood Hits	351	Shared Neighborhood Hits	233
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP6_HUMAN
θ value	θ > 10 (rank : 786)	NC score	0.165442 (rank : 409)
Query Neighborhood Hits	582	Target Neighborhood Hits	235	Shared Neighborhood Hits	139
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 787)	NC score	0.162743 (rank : 415)
Query Neighborhood Hits	582	Target Neighborhood Hits	232	Shared Neighborhood Hits	136
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRRC3_MOUSE
θ value	θ > 10 (rank : 788)	NC score	0.051621 (rank : 812)
Query Neighborhood Hits	582	Target Neighborhood Hits	236	Shared Neighborhood Hits	10
SwissProt Accessions	P59034	Gene names	Lrrc3
Domain Architecture
Description	Leucine-rich repeat-containing protein 3 precursor.

LRRC4_HUMAN
θ value	θ > 10 (rank : 789)	NC score	0.050244 (rank : 825)
Query Neighborhood Hits	582	Target Neighborhood Hits	444	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

LRRN1_HUMAN
θ value	θ > 10 (rank : 790)	NC score	0.055192 (rank : 759)
Query Neighborhood Hits	582	Target Neighborhood Hits	518	Shared Neighborhood Hits	33
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LRRN1_MOUSE
θ value	θ > 10 (rank : 791)	NC score	0.054001 (rank : 778)
Query Neighborhood Hits	582	Target Neighborhood Hits	508	Shared Neighborhood Hits	32
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LRRN3_HUMAN
θ value	θ > 10 (rank : 792)	NC score	0.054147 (rank : 775)
Query Neighborhood Hits	582	Target Neighborhood Hits	461	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRRN5_HUMAN
θ value	θ > 10 (rank : 793)	NC score	0.052644 (rank : 796)
Query Neighborhood Hits	582	Target Neighborhood Hits	493	Shared Neighborhood Hits	26
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

LYAM1_HUMAN
θ value	θ > 10 (rank : 794)	NC score	0.245932 (rank : 316)
Query Neighborhood Hits	582	Target Neighborhood Hits	315	Shared Neighborhood Hits	190
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MASP1_HUMAN
θ value	θ > 10 (rank : 795)	NC score	0.063645 (rank : 680)
Query Neighborhood Hits	582	Target Neighborhood Hits	369	Shared Neighborhood Hits	121
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 796)	NC score	0.062496 (rank : 688)
Query Neighborhood Hits	582	Target Neighborhood Hits	364	Shared Neighborhood Hits	121
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 797)	NC score	0.068656 (rank : 652)
Query Neighborhood Hits	582	Target Neighborhood Hits	364	Shared Neighborhood Hits	121
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 798)	NC score	0.069292 (rank : 648)
Query Neighborhood Hits	582	Target Neighborhood Hits	382	Shared Neighborhood Hits	128
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MATN1_HUMAN
θ value	θ > 10 (rank : 799)	NC score	0.100557 (rank : 544)
Query Neighborhood Hits	582	Target Neighborhood Hits	191	Shared Neighborhood Hits	114
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 800)	NC score	0.100831 (rank : 543)
Query Neighborhood Hits	582	Target Neighborhood Hits	186	Shared Neighborhood Hits	111
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN2_HUMAN
θ value	θ > 10 (rank : 801)	NC score	0.418056 (rank : 220)
Query Neighborhood Hits	582	Target Neighborhood Hits	365	Shared Neighborhood Hits	234
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 802)	NC score	0.406062 (rank : 229)
Query Neighborhood Hits	582	Target Neighborhood Hits	356	Shared Neighborhood Hits	234
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 803)	NC score	0.324992 (rank : 266)
Query Neighborhood Hits	582	Target Neighborhood Hits	268	Shared Neighborhood Hits	184
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 804)	NC score	0.323199 (rank : 267)
Query Neighborhood Hits	582	Target Neighborhood Hits	261	Shared Neighborhood Hits	187
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MCSP_HUMAN
θ value	θ > 10 (rank : 805)	NC score	0.065646 (rank : 671)
Query Neighborhood Hits	582	Target Neighborhood Hits	48	Shared Neighborhood Hits	31
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MDGA1_HUMAN
θ value	θ > 10 (rank : 806)	NC score	0.050320 (rank : 824)
Query Neighborhood Hits	582	Target Neighborhood Hits	358	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MEP1B_HUMAN
θ value	θ > 10 (rank : 807)	NC score	0.060706 (rank : 701)
Query Neighborhood Hits	582	Target Neighborhood Hits	98	Shared Neighborhood Hits	55
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MKS3_HUMAN
θ value	θ > 10 (rank : 808)	NC score	0.124716 (rank : 483)
Query Neighborhood Hits	582	Target Neighborhood Hits	79	Shared Neighborhood Hits	69
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

MKS3_MOUSE
θ value	θ > 10 (rank : 809)	NC score	0.157966 (rank : 427)
Query Neighborhood Hits	582	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MT1A_HUMAN
θ value	θ > 10 (rank : 810)	NC score	0.126714 (rank : 480)
Query Neighborhood Hits	582	Target Neighborhood Hits	74	Shared Neighborhood Hits	51
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
θ value	θ > 10 (rank : 811)	NC score	0.118153 (rank : 505)
Query Neighborhood Hits	582	Target Neighborhood Hits	87	Shared Neighborhood Hits	60
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1E_HUMAN
θ value	θ > 10 (rank : 812)	NC score	0.085222 (rank : 578)
Query Neighborhood Hits	582	Target Neighborhood Hits	75	Shared Neighborhood Hits	52
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT1F_HUMAN
θ value	θ > 10 (rank : 813)	NC score	0.066955 (rank : 662)
Query Neighborhood Hits	582	Target Neighborhood Hits	73	Shared Neighborhood Hits	47
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1G_HUMAN
θ value	θ > 10 (rank : 814)	NC score	0.071700 (rank : 632)
Query Neighborhood Hits	582	Target Neighborhood Hits	63	Shared Neighborhood Hits	34
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

MT1H_HUMAN
θ value	θ > 10 (rank : 815)	NC score	0.111400 (rank : 523)
Query Neighborhood Hits	582	Target Neighborhood Hits	78	Shared Neighborhood Hits	53
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT1I_HUMAN
θ value	θ > 10 (rank : 816)	NC score	0.056148 (rank : 748)
Query Neighborhood Hits	582	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

MT1L_HUMAN
θ value	θ > 10 (rank : 817)	NC score	0.077620 (rank : 607)
Query Neighborhood Hits	582	Target Neighborhood Hits	73	Shared Neighborhood Hits	48
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT1M_HUMAN
θ value	θ > 10 (rank : 818)	NC score	0.054018 (rank : 777)
Query Neighborhood Hits	582	Target Neighborhood Hits	72	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

MT1X_HUMAN
θ value	θ > 10 (rank : 819)	NC score	0.145004 (rank : 446)
Query Neighborhood Hits	582	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT1_MOUSE
θ value	θ > 10 (rank : 820)	NC score	0.100847 (rank : 542)
Query Neighborhood Hits	582	Target Neighborhood Hits	72	Shared Neighborhood Hits	45
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_HUMAN
θ value	θ > 10 (rank : 821)	NC score	0.060308 (rank : 706)
Query Neighborhood Hits	582	Target Neighborhood Hits	69	Shared Neighborhood Hits	46
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

MT2_MOUSE
θ value	θ > 10 (rank : 822)	NC score	0.108702 (rank : 526)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	49
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT3_MOUSE
θ value	θ > 10 (rank : 823)	NC score	0.225419 (rank : 330)
Query Neighborhood Hits	582	Target Neighborhood Hits	68	Shared Neighborhood Hits	50
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_MOUSE
θ value	θ > 10 (rank : 824)	NC score	0.174600 (rank : 389)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	76
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.181668 (rank : 377)
Query Neighborhood Hits	582	Target Neighborhood Hits	164	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MUCDL_HUMAN
θ value	θ > 10 (rank : 826)	NC score	0.063922 (rank : 679)
Query Neighborhood Hits	582	Target Neighborhood Hits	777	Shared Neighborhood Hits	59
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MUCDL_MOUSE
θ value	θ > 10 (rank : 827)	NC score	0.061208 (rank : 695)
Query Neighborhood Hits	582	Target Neighborhood Hits	461	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NEO1_HUMAN
θ value	θ > 10 (rank : 828)	NC score	0.059750 (rank : 714)
Query Neighborhood Hits	582	Target Neighborhood Hits	530	Shared Neighborhood Hits	49
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	θ > 10 (rank : 829)	NC score	0.060195 (rank : 708)
Query Neighborhood Hits	582	Target Neighborhood Hits	523	Shared Neighborhood Hits	47
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NEU1_MOUSE
θ value	θ > 10 (rank : 830)	NC score	0.068845 (rank : 651)
Query Neighborhood Hits	582	Target Neighborhood Hits	64	Shared Neighborhood Hits	54
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

NFASC_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.051930 (rank : 808)
Query Neighborhood Hits	582	Target Neighborhood Hits	497	Shared Neighborhood Hits	50
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NOV_HUMAN
θ value	θ > 10 (rank : 832)	NC score	0.074033 (rank : 619)
Query Neighborhood Hits	582	Target Neighborhood Hits	128	Shared Neighborhood Hits	74
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOV_MOUSE
θ value	θ > 10 (rank : 833)	NC score	0.065471 (rank : 673)
Query Neighborhood Hits	582	Target Neighborhood Hits	130	Shared Neighborhood Hits	70
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NPHN_HUMAN
θ value	θ > 10 (rank : 834)	NC score	0.052558 (rank : 798)
Query Neighborhood Hits	582	Target Neighborhood Hits	362	Shared Neighborhood Hits	30
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NRCAM_HUMAN
θ value	θ > 10 (rank : 835)	NC score	0.052618 (rank : 797)
Query Neighborhood Hits	582	Target Neighborhood Hits	439	Shared Neighborhood Hits	41
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
θ value	θ > 10 (rank : 836)	NC score	0.051233 (rank : 814)
Query Neighborhood Hits	582	Target Neighborhood Hits	432	Shared Neighborhood Hits	41
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

NRG1_HUMAN
θ value	θ > 10 (rank : 837)	NC score	0.178238 (rank : 381)
Query Neighborhood Hits	582	Target Neighborhood Hits	285	Shared Neighborhood Hits	98
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG3_HUMAN
θ value	θ > 10 (rank : 838)	NC score	0.072813 (rank : 628)
Query Neighborhood Hits	582	Target Neighborhood Hits	119	Shared Neighborhood Hits	63
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG3_MOUSE
θ value	θ > 10 (rank : 839)	NC score	0.076535 (rank : 611)
Query Neighborhood Hits	582	Target Neighborhood Hits	132	Shared Neighborhood Hits	73
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG4_HUMAN
θ value	θ > 10 (rank : 840)	NC score	0.160447 (rank : 421)
Query Neighborhood Hits	582	Target Neighborhood Hits	85	Shared Neighborhood Hits	67
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 841)	NC score	0.161071 (rank : 419)
Query Neighborhood Hits	582	Target Neighborhood Hits	79	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRP1_HUMAN
θ value	θ > 10 (rank : 842)	NC score	0.061620 (rank : 691)
Query Neighborhood Hits	582	Target Neighborhood Hits	119	Shared Neighborhood Hits	25
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 843)	NC score	0.061935 (rank : 689)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	24
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.065731 (rank : 669)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	26
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 845)	NC score	0.063051 (rank : 683)
Query Neighborhood Hits	582	Target Neighborhood Hits	113	Shared Neighborhood Hits	23
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRX1B_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.254313 (rank : 311)
Query Neighborhood Hits	582	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

NRX2B_HUMAN
θ value	θ > 10 (rank : 847)	NC score	0.173938 (rank : 390)
Query Neighborhood Hits	582	Target Neighborhood Hits	481	Shared Neighborhood Hits	55
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

OBSL1_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.053712 (rank : 782)
Query Neighborhood Hits	582	Target Neighborhood Hits	354	Shared Neighborhood Hits	18
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

ODFP_MOUSE
θ value	θ > 10 (rank : 849)	NC score	0.091252 (rank : 558)
Query Neighborhood Hits	582	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PAPPA_HUMAN
θ value	θ > 10 (rank : 850)	NC score	0.075859 (rank : 614)
Query Neighborhood Hits	582	Target Neighborhood Hits	161	Shared Neighborhood Hits	73
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PC11X_HUMAN
θ value	θ > 10 (rank : 851)	NC score	0.055439 (rank : 755)
Query Neighborhood Hits	582	Target Neighborhood Hits	199	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

PC11Y_HUMAN
θ value	θ > 10 (rank : 852)	NC score	0.055381 (rank : 756)
Query Neighborhood Hits	582	Target Neighborhood Hits	205	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

PCD12_MOUSE
θ value	θ > 10 (rank : 853)	NC score	0.050350 (rank : 823)
Query Neighborhood Hits	582	Target Neighborhood Hits	199	Shared Neighborhood Hits	11
SwissProt Accessions	O55134	Gene names	Pcdh12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

PCD15_HUMAN
θ value	θ > 10 (rank : 854)	NC score	0.072857 (rank : 627)
Query Neighborhood Hits	582	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD15_MOUSE
θ value	θ > 10 (rank : 855)	NC score	0.072243 (rank : 630)
Query Neighborhood Hits	582	Target Neighborhood Hits	262	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD16_HUMAN
θ value	θ > 10 (rank : 856)	NC score	0.073104 (rank : 626)
Query Neighborhood Hits	582	Target Neighborhood Hits	245	Shared Neighborhood Hits	20
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PCD20_HUMAN
θ value	θ > 10 (rank : 857)	NC score	0.056592 (rank : 739)
Query Neighborhood Hits	582	Target Neighborhood Hits	153	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N6Y1, Q8NDN4, Q9NRT9	Gene names	PCDH20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor (Protocadherin-13).

PCD20_MOUSE
θ value	θ > 10 (rank : 858)	NC score	0.056607 (rank : 738)
Query Neighborhood Hits	582	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BIZ0, Q8BIV2	Gene names	Pcdh20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor.

PCDH1_HUMAN
θ value	θ > 10 (rank : 859)	NC score	0.058233 (rank : 729)
Query Neighborhood Hits	582	Target Neighborhood Hits	174	Shared Neighborhood Hits	12
SwissProt Accessions	Q08174	Gene names	PCDH1
Domain Architecture
Description	Protocadherin-1 precursor (Protocadherin-42) (PC42) (Cadherin-like protein 1).

PCDH7_HUMAN
θ value	θ > 10 (rank : 860)	NC score	0.057294 (rank : 733)
Query Neighborhood Hits	582	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

PCDH9_HUMAN
θ value	θ > 10 (rank : 861)	NC score	0.056865 (rank : 734)
Query Neighborhood Hits	582	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

PCDLK_HUMAN
θ value	θ > 10 (rank : 862)	NC score	0.067024 (rank : 660)
Query Neighborhood Hits	582	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

PCSK6_HUMAN
θ value	θ > 10 (rank : 863)	NC score	0.199777 (rank : 349)
Query Neighborhood Hits	582	Target Neighborhood Hits	298	Shared Neighborhood Hits	152
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PGCA_MOUSE
θ value	θ > 10 (rank : 864)	NC score	0.054263 (rank : 771)
Query Neighborhood Hits	582	Target Neighborhood Hits	643	Shared Neighborhood Hits	56
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PGH1_HUMAN
θ value	θ > 10 (rank : 865)	NC score	0.152847 (rank : 436)
Query Neighborhood Hits	582	Target Neighborhood Hits	91	Shared Neighborhood Hits	71
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH1_MOUSE
θ value	θ > 10 (rank : 866)	NC score	0.173901 (rank : 391)
Query Neighborhood Hits	582	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_HUMAN
θ value	θ > 10 (rank : 867)	NC score	0.189729 (rank : 358)
Query Neighborhood Hits	582	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
θ value	θ > 10 (rank : 868)	NC score	0.211264 (rank : 341)
Query Neighborhood Hits	582	Target Neighborhood Hits	113	Shared Neighborhood Hits	100
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PGLB_HUMAN
θ value	θ > 10 (rank : 869)	NC score	0.051339 (rank : 813)
Query Neighborhood Hits	582	Target Neighborhood Hits	250	Shared Neighborhood Hits	11
SwissProt Accessions	Q99645, Q8NEJ5	Gene names	DSPG3, PGLB
Domain Architecture
Description	Dermatan sulfate proteoglycan 3 precursor (Epiphycan) (Small chondroitin/dermatan sulfate proteoglycan) (Proteoglycan-Lb) (PG-Lb).

PHXR5_MOUSE
θ value	θ > 10 (rank : 870)	NC score	0.090611 (rank : 559)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PKD1_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.055316 (rank : 757)
Query Neighborhood Hits	582	Target Neighborhood Hits	387	Shared Neighborhood Hits	31
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

PROP_MOUSE
θ value	θ > 10 (rank : 872)	NC score	0.053922 (rank : 780)
Query Neighborhood Hits	582	Target Neighborhood Hits	165	Shared Neighborhood Hits	49
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PRP2_MOUSE
θ value	θ > 10 (rank : 873)	NC score	0.053094 (rank : 791)
Query Neighborhood Hits	582	Target Neighborhood Hits	347	Shared Neighborhood Hits	47
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PUNC_HUMAN
θ value	θ > 10 (rank : 874)	NC score	0.058423 (rank : 726)
Query Neighborhood Hits	582	Target Neighborhood Hits	449	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

PUNC_MOUSE
θ value	θ > 10 (rank : 875)	NC score	0.058281 (rank : 728)
Query Neighborhood Hits	582	Target Neighborhood Hits	501	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

RELN_HUMAN
θ value	θ > 10 (rank : 876)	NC score	0.187597 (rank : 362)
Query Neighborhood Hits	582	Target Neighborhood Hits	233	Shared Neighborhood Hits	172
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	θ > 10 (rank : 877)	NC score	0.195581 (rank : 354)
Query Neighborhood Hits	582	Target Neighborhood Hits	235	Shared Neighborhood Hits	178
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

ROBO3_HUMAN
θ value	θ > 10 (rank : 878)	NC score	0.050467 (rank : 822)
Query Neighborhood Hits	582	Target Neighborhood Hits	570	Shared Neighborhood Hits	58
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

RSPO2_HUMAN
θ value	θ > 10 (rank : 879)	NC score	0.066341 (rank : 667)
Query Neighborhood Hits	582	Target Neighborhood Hits	90	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
θ value	θ > 10 (rank : 880)	NC score	0.066177 (rank : 668)
Query Neighborhood Hits	582	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO3_HUMAN
θ value	θ > 10 (rank : 881)	NC score	0.082443 (rank : 586)
Query Neighborhood Hits	582	Target Neighborhood Hits	128	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 882)	NC score	0.071937 (rank : 631)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	62
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 883)	NC score	0.086310 (rank : 576)
Query Neighborhood Hits	582	Target Neighborhood Hits	110	Shared Neighborhood Hits	65
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 884)	NC score	0.077875 (rank : 604)
Query Neighborhood Hits	582	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SDK1_HUMAN
θ value	θ > 10 (rank : 885)	NC score	0.060956 (rank : 697)
Query Neighborhood Hits	582	Target Neighborhood Hits	511	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
θ value	θ > 10 (rank : 886)	NC score	0.061596 (rank : 692)
Query Neighborhood Hits	582	Target Neighborhood Hits	495	Shared Neighborhood Hits	51
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
θ value	θ > 10 (rank : 887)	NC score	0.060208 (rank : 707)
Query Neighborhood Hits	582	Target Neighborhood Hits	495	Shared Neighborhood Hits	47
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
θ value	θ > 10 (rank : 888)	NC score	0.061169 (rank : 696)
Query Neighborhood Hits	582	Target Neighborhood Hits	480	Shared Neighborhood Hits	47
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SHAN1_HUMAN
θ value	θ > 10 (rank : 889)	NC score	0.051623 (rank : 811)
Query Neighborhood Hits	582	Target Neighborhood Hits	1041	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SORL_HUMAN
θ value	θ > 10 (rank : 890)	NC score	0.270881 (rank : 302)
Query Neighborhood Hits	582	Target Neighborhood Hits	440	Shared Neighborhood Hits	226
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SPR2B_MOUSE
θ value	θ > 10 (rank : 891)	NC score	0.078490 (rank : 601)
Query Neighborhood Hits	582	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2D_MOUSE
θ value	θ > 10 (rank : 892)	NC score	0.100911 (rank : 541)
Query Neighborhood Hits	582	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_HUMAN
θ value	θ > 10 (rank : 893)	NC score	0.053959 (rank : 779)
Query Neighborhood Hits	582	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2E_MOUSE
θ value	θ > 10 (rank : 894)	NC score	0.062866 (rank : 685)
Query Neighborhood Hits	582	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2F_HUMAN
θ value	θ > 10 (rank : 895)	NC score	0.077836 (rank : 605)
Query Neighborhood Hits	582	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2F_MOUSE
θ value	θ > 10 (rank : 896)	NC score	0.055600 (rank : 753)
Query Neighborhood Hits	582	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SPR2G_MOUSE
θ value	θ > 10 (rank : 897)	NC score	0.089035 (rank : 566)
Query Neighborhood Hits	582	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 898)	NC score	0.088919 (rank : 568)
Query Neighborhood Hits	582	Target Neighborhood Hits	82	Shared Neighborhood Hits	36
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2I_MOUSE
θ value	θ > 10 (rank : 899)	NC score	0.070058 (rank : 642)
Query Neighborhood Hits	582	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

ST14_MOUSE
θ value	θ > 10 (rank : 900)	NC score	0.113010 (rank : 516)
Query Neighborhood Hits	582	Target Neighborhood Hits	419	Shared Neighborhood Hits	172
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

SUSD1_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.417479 (rank : 221)
Query Neighborhood Hits	582	Target Neighborhood Hits	285	Shared Neighborhood Hits	202
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TACD2_HUMAN
θ value	θ > 10 (rank : 902)	NC score	0.052008 (rank : 807)
Query Neighborhood Hits	582	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

TGFA_HUMAN
θ value	θ > 10 (rank : 903)	NC score	0.103355 (rank : 538)
Query Neighborhood Hits	582	Target Neighborhood Hits	61	Shared Neighborhood Hits	44
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TGFA_MOUSE
θ value	θ > 10 (rank : 904)	NC score	0.089794 (rank : 562)
Query Neighborhood Hits	582	Target Neighborhood Hits	62	Shared Neighborhood Hits	42
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

THYG_HUMAN
θ value	θ > 10 (rank : 905)	NC score	0.066569 (rank : 664)
Query Neighborhood Hits	582	Target Neighborhood Hits	154	Shared Neighborhood Hits	67
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

THYG_MOUSE
θ value	θ > 10 (rank : 906)	NC score	0.059318 (rank : 717)
Query Neighborhood Hits	582	Target Neighborhood Hits	161	Shared Neighborhood Hits	69
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TLL1_HUMAN
θ value	θ > 10 (rank : 907)	NC score	0.120942 (rank : 496)
Query Neighborhood Hits	582	Target Neighborhood Hits	236	Shared Neighborhood Hits	140
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 908)	NC score	0.125852 (rank : 482)
Query Neighborhood Hits	582	Target Neighborhood Hits	237	Shared Neighborhood Hits	143
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 909)	NC score	0.121583 (rank : 493)
Query Neighborhood Hits	582	Target Neighborhood Hits	241	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 910)	NC score	0.114185 (rank : 512)
Query Neighborhood Hits	582	Target Neighborhood Hits	240	Shared Neighborhood Hits	143
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TMG1_HUMAN
θ value	θ > 10 (rank : 911)	NC score	0.051217 (rank : 815)
Query Neighborhood Hits	582	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

TMPS6_HUMAN
θ value	θ > 10 (rank : 912)	NC score	0.087039 (rank : 573)
Query Neighborhood Hits	582	Target Neighborhood Hits	338	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 913)	NC score	0.082832 (rank : 584)
Query Neighborhood Hits	582	Target Neighborhood Hits	341	Shared Neighborhood Hits	123
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_HUMAN
θ value	θ > 10 (rank : 914)	NC score	0.059231 (rank : 719)
Query Neighborhood Hits	582	Target Neighborhood Hits	275	Shared Neighborhood Hits	68
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 915)	NC score	0.059506 (rank : 715)
Query Neighborhood Hits	582	Target Neighborhood Hits	275	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TNR11_HUMAN
θ value	θ > 10 (rank : 916)	NC score	0.087560 (rank : 572)
Query Neighborhood Hits	582	Target Neighborhood Hits	135	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
θ value	θ > 10 (rank : 917)	NC score	0.067842 (rank : 655)
Query Neighborhood Hits	582	Target Neighborhood Hits	121	Shared Neighborhood Hits	59
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR14_HUMAN
θ value	θ > 10 (rank : 918)	NC score	0.141792 (rank : 451)
Query Neighborhood Hits	582	Target Neighborhood Hits	149	Shared Neighborhood Hits	82
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR18_HUMAN
θ value	θ > 10 (rank : 919)	NC score	0.053107 (rank : 789)
Query Neighborhood Hits	582	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR19_HUMAN
θ value	θ > 10 (rank : 920)	NC score	0.077186 (rank : 609)
Query Neighborhood Hits	582	Target Neighborhood Hits	89	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 921)	NC score	0.087650 (rank : 571)
Query Neighborhood Hits	582	Target Neighborhood Hits	100	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR1A_MOUSE
θ value	θ > 10 (rank : 922)	NC score	0.055500 (rank : 754)
Query Neighborhood Hits	582	Target Neighborhood Hits	131	Shared Neighborhood Hits	49
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR1B_HUMAN
θ value	θ > 10 (rank : 923)	NC score	0.063270 (rank : 681)
Query Neighborhood Hits	582	Target Neighborhood Hits	127	Shared Neighborhood Hits	55
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR23_MOUSE
θ value	θ > 10 (rank : 924)	NC score	0.140611 (rank : 454)
Query Neighborhood Hits	582	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR25_HUMAN
θ value	θ > 10 (rank : 925)	NC score	0.170078 (rank : 399)
Query Neighborhood Hits	582	Target Neighborhood Hits	172	Shared Neighborhood Hits	82
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR3_HUMAN
θ value	θ > 10 (rank : 926)	NC score	0.074021 (rank : 620)
Query Neighborhood Hits	582	Target Neighborhood Hits	145	Shared Neighborhood Hits	55
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR3_MOUSE
θ value	θ > 10 (rank : 927)	NC score	0.093826 (rank : 555)
Query Neighborhood Hits	582	Target Neighborhood Hits	113	Shared Neighborhood Hits	61
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR4_HUMAN
θ value	θ > 10 (rank : 928)	NC score	0.166154 (rank : 405)
Query Neighborhood Hits	582	Target Neighborhood Hits	152	Shared Neighborhood Hits	76
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR5_HUMAN
θ value	θ > 10 (rank : 929)	NC score	0.069481 (rank : 646)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	53
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR5_MOUSE
θ value	θ > 10 (rank : 930)	NC score	0.096516 (rank : 551)
Query Neighborhood Hits	582	Target Neighborhood Hits	131	Shared Neighborhood Hits	68
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR6B_HUMAN
θ value	θ > 10 (rank : 931)	NC score	0.073699 (rank : 622)
Query Neighborhood Hits	582	Target Neighborhood Hits	103	Shared Neighborhood Hits	47
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR6_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.058392 (rank : 727)
Query Neighborhood Hits	582	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
θ value	θ > 10 (rank : 933)	NC score	0.082253 (rank : 588)
Query Neighborhood Hits	582	Target Neighborhood Hits	99	Shared Neighborhood Hits	54
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
θ value	θ > 10 (rank : 934)	NC score	0.126905 (rank : 479)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	67
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR8_MOUSE
θ value	θ > 10 (rank : 935)	NC score	0.105156 (rank : 533)
Query Neighborhood Hits	582	Target Neighborhood Hits	208	Shared Neighborhood Hits	80
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR9_HUMAN
θ value	θ > 10 (rank : 936)	NC score	0.109172 (rank : 525)
Query Neighborhood Hits	582	Target Neighborhood Hits	166	Shared Neighborhood Hits	79
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR9_MOUSE
θ value	θ > 10 (rank : 937)	NC score	0.118390 (rank : 503)
Query Neighborhood Hits	582	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TR10B_MOUSE
θ value	θ > 10 (rank : 938)	NC score	0.054106 (rank : 776)
Query Neighborhood Hits	582	Target Neighborhood Hits	76	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR19L_HUMAN
θ value	θ > 10 (rank : 939)	NC score	0.057618 (rank : 731)
Query Neighborhood Hits	582	Target Neighborhood Hits	99	Shared Neighborhood Hits	34
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR19L_MOUSE
θ value	θ > 10 (rank : 940)	NC score	0.054665 (rank : 765)
Query Neighborhood Hits	582	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TSG6_HUMAN
θ value	θ > 10 (rank : 941)	NC score	0.054247 (rank : 772)
Query Neighborhood Hits	582	Target Neighborhood Hits	91	Shared Neighborhood Hits	20
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 942)	NC score	0.054292 (rank : 768)
Query Neighborhood Hits	582	Target Neighborhood Hits	91	Shared Neighborhood Hits	19
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

UROK_MOUSE
θ value	θ > 10 (rank : 943)	NC score	0.076156 (rank : 612)
Query Neighborhood Hits	582	Target Neighborhood Hits	273	Shared Neighborhood Hits	112
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROL1_HUMAN
θ value	θ > 10 (rank : 944)	NC score	0.151154 (rank : 439)
Query Neighborhood Hits	582	Target Neighborhood Hits	213	Shared Neighborhood Hits	120
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

VEGFC_HUMAN
θ value	θ > 10 (rank : 945)	NC score	0.139328 (rank : 457)
Query Neighborhood Hits	582	Target Neighborhood Hits	128	Shared Neighborhood Hits	101
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

WFDC3_HUMAN
θ value	θ > 10 (rank : 946)	NC score	0.144058 (rank : 449)
Query Neighborhood Hits	582	Target Neighborhood Hits	138	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WISP2_HUMAN
θ value	θ > 10 (rank : 947)	NC score	0.069526 (rank : 645)
Query Neighborhood Hits	582	Target Neighborhood Hits	126	Shared Neighborhood Hits	61
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
θ value	θ > 10 (rank : 948)	NC score	0.066982 (rank : 661)
Query Neighborhood Hits	582	Target Neighborhood Hits	129	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

XLRS1_HUMAN
θ value	θ > 10 (rank : 949)	NC score	0.086605 (rank : 575)
Query Neighborhood Hits	582	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

XLRS1_MOUSE
θ value	θ > 10 (rank : 950)	NC score	0.088547 (rank : 570)
Query Neighborhood Hits	582	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

ZNFX1_HUMAN
θ value	θ > 10 (rank : 951)	NC score	0.120042 (rank : 498)
Query Neighborhood Hits	582	Target Neighborhood Hits	308	Shared Neighborhood Hits	112
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

Hits sorted by NC score

AGRIN_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	582	Target Neighborhood Hits	582	Shared Neighborhood Hits	582
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

LAMA5_MOUSE
NC score	0.758713 (rank : 2)	θ value	2.59989e-23 (rank : 28)
Query Neighborhood Hits	582	Target Neighborhood Hits	828	Shared Neighborhood Hits	346
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

CRUM1_HUMAN
NC score	0.756041 (rank : 3)	θ value	8.93572e-24 (rank : 26)
Query Neighborhood Hits	582	Target Neighborhood Hits	457	Shared Neighborhood Hits	345
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
NC score	0.755295 (rank : 4)	θ value	1.5773e-20 (rank : 42)
Query Neighborhood Hits	582	Target Neighborhood Hits	444	Shared Neighborhood Hits	342
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

SREC_HUMAN
NC score	0.752589 (rank : 5)	θ value	2.35696e-16 (rank : 57)
Query Neighborhood Hits	582	Target Neighborhood Hits	645	Shared Neighborhood Hits	372
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LAMA1_MOUSE
NC score	0.750937 (rank : 6)	θ value	1.29031e-22 (rank : 34)
Query Neighborhood Hits	582	Target Neighborhood Hits	838	Shared Neighborhood Hits	327
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_HUMAN
NC score	0.749386 (rank : 7)	θ value	6.84181e-24 (rank : 24)
Query Neighborhood Hits	582	Target Neighborhood Hits	804	Shared Neighborhood Hits	315
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA5_HUMAN
NC score	0.744610 (rank : 8)	θ value	3.75424e-22 (rank : 36)
Query Neighborhood Hits	582	Target Neighborhood Hits	976	Shared Neighborhood Hits	354
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

CRUM2_HUMAN
NC score	0.743997 (rank : 9)	θ value	3.28887e-18 (rank : 51)
Query Neighborhood Hits	582	Target Neighborhood Hits	453	Shared Neighborhood Hits	341
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

SREC2_MOUSE
NC score	0.742354 (rank : 10)	θ value	8.38298e-14 (rank : 70)
Query Neighborhood Hits	582	Target Neighborhood Hits	605	Shared Neighborhood Hits	360
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC2_HUMAN
NC score	0.737630 (rank : 11)	θ value	1.42992e-13 (rank : 72)
Query Neighborhood Hits	582	Target Neighborhood Hits	645	Shared Neighborhood Hits	359
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

MEGF9_HUMAN
NC score	0.735318 (rank : 12)	θ value	4.74913e-17 (rank : 54)
Query Neighborhood Hits	582	Target Neighborhood Hits	557	Shared Neighborhood Hits	300
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

DLL1_MOUSE
NC score	0.729220 (rank : 13)	θ value	4.16044e-13 (rank : 74)
Query Neighborhood Hits	582	Target Neighborhood Hits	456	Shared Neighborhood Hits	351
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

JAG1_MOUSE
NC score	0.728971 (rank : 14)	θ value	6.00763e-12 (rank : 84)
Query Neighborhood Hits	582	Target Neighborhood Hits	518	Shared Neighborhood Hits	375
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

DLL1_HUMAN
NC score	0.728568 (rank : 15)	θ value	7.84624e-12 (rank : 86)
Query Neighborhood Hits	582	Target Neighborhood Hits	455	Shared Neighborhood Hits	348
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

LAMC3_MOUSE
NC score	0.728400 (rank : 16)	θ value	7.30988e-26 (rank : 18)
Query Neighborhood Hits	582	Target Neighborhood Hits	624	Shared Neighborhood Hits	298
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

JAG1_HUMAN
NC score	0.728291 (rank : 17)	θ value	1.58096e-12 (rank : 78)
Query Neighborhood Hits	582	Target Neighborhood Hits	514	Shared Neighborhood Hits	373
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

DLL4_MOUSE
NC score	0.728120 (rank : 18)	θ value	3.29651e-10 (rank : 99)
Query Neighborhood Hits	582	Target Neighborhood Hits	440	Shared Neighborhood Hits	344
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

JAG2_HUMAN
NC score	0.726963 (rank : 19)	θ value	1.99529e-15 (rank : 62)
Query Neighborhood Hits	582	Target Neighborhood Hits	491	Shared Neighborhood Hits	364
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

LAMC3_HUMAN
NC score	0.726150 (rank : 20)	θ value	1.6852e-22 (rank : 35)
Query Neighborhood Hits	582	Target Neighborhood Hits	588	Shared Neighborhood Hits	302
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

JAG2_MOUSE
NC score	0.725135 (rank : 21)	θ value	4.91457e-14 (rank : 69)
Query Neighborhood Hits	582	Target Neighborhood Hits	504	Shared Neighborhood Hits	365
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

DLK_HUMAN
NC score	0.725110 (rank : 22)	θ value	1.17247e-07 (rank : 122)
Query Neighborhood Hits	582	Target Neighborhood Hits	401	Shared Neighborhood Hits	332
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL4_HUMAN
NC score	0.723646 (rank : 23)	θ value	2.13673e-09 (rank : 106)
Query Neighborhood Hits	582	Target Neighborhood Hits	435	Shared Neighborhood Hits	336
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL3_HUMAN
NC score	0.722834 (rank : 24)	θ value	8.97725e-08 (rank : 120)
Query Neighborhood Hits	582	Target Neighborhood Hits	419	Shared Neighborhood Hits	334
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DNER_HUMAN
NC score	0.721650 (rank : 25)	θ value	7.59969e-07 (rank : 135)
Query Neighborhood Hits	582	Target Neighborhood Hits	460	Shared Neighborhood Hits	341
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
NC score	0.721249 (rank : 26)	θ value	5.81887e-07 (rank : 131)
Query Neighborhood Hits	582	Target Neighborhood Hits	413	Shared Neighborhood Hits	329
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

LAMB2_MOUSE
NC score	0.720570 (rank : 27)	θ value	1.12775e-26 (rank : 16)
Query Neighborhood Hits	582	Target Neighborhood Hits	722	Shared Neighborhood Hits	308
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB2_HUMAN
NC score	0.720028 (rank : 28)	θ value	2.59989e-23 (rank : 29)
Query Neighborhood Hits	582	Target Neighborhood Hits	692	Shared Neighborhood Hits	298
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

DLK_MOUSE
NC score	0.720003 (rank : 29)	θ value	8.11959e-09 (rank : 112)
Query Neighborhood Hits	582	Target Neighborhood Hits	374	Shared Neighborhood Hits	320
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

MEGF6_HUMAN
NC score	0.718347 (rank : 30)	θ value	2.27234e-27 (rank : 14)
Query Neighborhood Hits	582	Target Neighborhood Hits	671	Shared Neighborhood Hits	402
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

DLL3_MOUSE
NC score	0.713453 (rank : 31)	θ value	6.21693e-09 (rank : 111)
Query Neighborhood Hits	582	Target Neighborhood Hits	399	Shared Neighborhood Hits	323
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

EGFL9_HUMAN
NC score	0.706494 (rank : 32)	θ value	6.43352e-06 (rank : 148)
Query Neighborhood Hits	582	Target Neighborhood Hits	365	Shared Neighborhood Hits	316
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
NC score	0.700267 (rank : 33)	θ value	8.40245e-06 (rank : 150)
Query Neighborhood Hits	582	Target Neighborhood Hits	379	Shared Neighborhood Hits	323
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

MEGF9_MOUSE
NC score	0.699121 (rank : 34)	θ value	3.07829e-16 (rank : 58)
Query Neighborhood Hits	582	Target Neighborhood Hits	896	Shared Neighborhood Hits	283
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMA2_HUMAN
NC score	0.696356 (rank : 35)	θ value	3.51386e-20 (rank : 44)
Query Neighborhood Hits	582	Target Neighborhood Hits	1092	Shared Neighborhood Hits	321
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC2_MOUSE
NC score	0.695104 (rank : 36)	θ value	6.85773e-16 (rank : 60)
Query Neighborhood Hits	582	Target Neighborhood Hits	614	Shared Neighborhood Hits	276
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMB3_MOUSE
NC score	0.693846 (rank : 37)	θ value	5.25075e-16 (rank : 59)
Query Neighborhood Hits	582	Target Neighborhood Hits	444	Shared Neighborhood Hits	237
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

NOTC1_MOUSE
NC score	0.691550 (rank : 38)	θ value	4.73814e-25 (rank : 23)
Query Neighborhood Hits	582	Target Neighborhood Hits	916	Shared Neighborhood Hits	388
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LAMA3_MOUSE
NC score	0.682694 (rank : 39)	θ value	7.58209e-15 (rank : 65)
Query Neighborhood Hits	582	Target Neighborhood Hits	859	Shared Neighborhood Hits	321
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

WIF1_MOUSE
NC score	0.681620 (rank : 40)	θ value	0.00035302 (rank : 206)
Query Neighborhood Hits	582	Target Neighborhood Hits	393	Shared Neighborhood Hits	330
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

LAMB3_HUMAN
NC score	0.677168 (rank : 41)	θ value	1.13037e-18 (rank : 50)
Query Neighborhood Hits	582	Target Neighborhood Hits	461	Shared Neighborhood Hits	215
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB1_MOUSE
NC score	0.676172 (rank : 42)	θ value	1.16704e-23 (rank : 27)
Query Neighborhood Hits	582	Target Neighborhood Hits	919	Shared Neighborhood Hits	282
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

NOTC1_HUMAN
NC score	0.673972 (rank : 43)	θ value	3.62785e-25 (rank : 21)
Query Neighborhood Hits	582	Target Neighborhood Hits	906	Shared Neighborhood Hits	390
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LAMC1_MOUSE
NC score	0.672795 (rank : 44)	θ value	7.82807e-20 (rank : 46)
Query Neighborhood Hits	582	Target Neighborhood Hits	856	Shared Neighborhood Hits	290
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
NC score	0.672205 (rank : 45)	θ value	2.35696e-16 (rank : 56)
Query Neighborhood Hits	582	Target Neighborhood Hits	715	Shared Neighborhood Hits	275
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

WIF1_HUMAN
NC score	0.671805 (rank : 46)	θ value	0.00390308 (rank : 257)
Query Neighborhood Hits	582	Target Neighborhood Hits	392	Shared Neighborhood Hits	328
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

NOTC3_MOUSE
NC score	0.671187 (rank : 47)	θ value	6.84181e-24 (rank : 25)
Query Neighborhood Hits	582	Target Neighborhood Hits	975	Shared Neighborhood Hits	406
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.670467 (rank : 48)	θ value	2.27234e-27 (rank : 15)
Query Neighborhood Hits	582	Target Neighborhood Hits	1062	Shared Neighborhood Hits	405
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NTNG2_HUMAN
NC score	0.669517 (rank : 49)	θ value	9.26847e-13 (rank : 77)
Query Neighborhood Hits	582	Target Neighborhood Hits	276	Shared Neighborhood Hits	233
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMA2_MOUSE
NC score	0.669099 (rank : 50)	θ value	8.65492e-19 (rank : 49)
Query Neighborhood Hits	582	Target Neighborhood Hits	1198	Shared Neighborhood Hits	328
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NTNG2_MOUSE
NC score	0.667250 (rank : 51)	θ value	3.29651e-10 (rank : 101)
Query Neighborhood Hits	582	Target Neighborhood Hits	276	Shared Neighborhood Hits	237
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NOTC2_MOUSE
NC score	0.661135 (rank : 52)	θ value	1.5773e-20 (rank : 43)
Query Neighborhood Hits	582	Target Neighborhood Hits	1069	Shared Neighborhood Hits	400
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
NC score	0.657185 (rank : 53)	θ value	3.39556e-23 (rank : 30)
Query Neighborhood Hits	582	Target Neighborhood Hits	1113	Shared Neighborhood Hits	408
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NTNG1_HUMAN
NC score	0.656055 (rank : 54)	θ value	5.43371e-13 (rank : 76)
Query Neighborhood Hits	582	Target Neighborhood Hits	247	Shared Neighborhood Hits	206
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LAMC1_HUMAN
NC score	0.655768 (rank : 55)	θ value	5.42112e-21 (rank : 39)
Query Neighborhood Hits	582	Target Neighborhood Hits	922	Shared Neighborhood Hits	294
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NOTC4_MOUSE
NC score	0.655624 (rank : 56)	θ value	5.99374e-20 (rank : 45)
Query Neighborhood Hits	582	Target Neighborhood Hits	872	Shared Neighborhood Hits	393
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_HUMAN
NC score	0.655592 (rank : 57)	θ value	2.43343e-21 (rank : 37)
Query Neighborhood Hits	582	Target Neighborhood Hits	905	Shared Neighborhood Hits	400
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NTNG1_MOUSE
NC score	0.654379 (rank : 58)	θ value	1.58096e-12 (rank : 80)
Query Neighborhood Hits	582	Target Neighborhood Hits	246	Shared Neighborhood Hits	206
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LAMB1_HUMAN
NC score	0.653044 (rank : 59)	θ value	5.79196e-23 (rank : 33)
Query Neighborhood Hits	582	Target Neighborhood Hits	1018	Shared Neighborhood Hits	294
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MEGF8_HUMAN
NC score	0.651602 (rank : 60)	θ value	4.0297e-08 (rank : 117)
Query Neighborhood Hits	582	Target Neighborhood Hits	528	Shared Neighborhood Hits	314
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

USH2A_MOUSE
NC score	0.648445 (rank : 61)	θ value	1.33526e-19 (rank : 47)
Query Neighborhood Hits	582	Target Neighborhood Hits	626	Shared Neighborhood Hits	294
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

MEGF8_MOUSE
NC score	0.640885 (rank : 62)	θ value	1.80886e-08 (rank : 114)
Query Neighborhood Hits	582	Target Neighborhood Hits	520	Shared Neighborhood Hits	308
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

STAB1_HUMAN
NC score	0.636236 (rank : 63)	θ value	2.88788e-06 (rank : 143)
Query Neighborhood Hits	582	Target Neighborhood Hits	546	Shared Neighborhood Hits	356
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB2_HUMAN
NC score	0.634767 (rank : 64)	θ value	8.67504e-11 (rank : 96)
Query Neighborhood Hits	582	Target Neighborhood Hits	534	Shared Neighborhood Hits	360
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

USH2A_HUMAN
NC score	0.634670 (rank : 65)	θ value	5.07402e-19 (rank : 48)
Query Neighborhood Hits	582	Target Neighborhood Hits	600	Shared Neighborhood Hits	271
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

STAB1_MOUSE
NC score	0.633160 (rank : 66)	θ value	3.77169e-06 (rank : 145)
Query Neighborhood Hits	582	Target Neighborhood Hits	566	Shared Neighborhood Hits	365
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_MOUSE
NC score	0.627599 (rank : 67)	θ value	3.77169e-06 (rank : 146)
Query Neighborhood Hits	582	Target Neighborhood Hits	528	Shared Neighborhood Hits	358
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

LAMA4_MOUSE
NC score	0.624516 (rank : 68)	θ value	3.52202e-12 (rank : 81)
Query Neighborhood Hits	582	Target Neighborhood Hits	584	Shared Neighborhood Hits	219
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

KRA51_HUMAN
NC score	0.623983 (rank : 69)	θ value	1.43324e-05 (rank : 161)
Query Neighborhood Hits	582	Target Neighborhood Hits	288	Shared Neighborhood Hits	210
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
NC score	0.620562 (rank : 70)	θ value	9.29e-05 (rank : 182)
Query Neighborhood Hits	582	Target Neighborhood Hits	331	Shared Neighborhood Hits	240
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

LAMA3_HUMAN
NC score	0.609339 (rank : 71)	θ value	5.81887e-07 (rank : 132)
Query Neighborhood Hits	582	Target Neighborhood Hits	760	Shared Neighborhood Hits	258
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

NET4_HUMAN
NC score	0.603947 (rank : 72)	θ value	2.98157e-11 (rank : 93)
Query Neighborhood Hits	582	Target Neighborhood Hits	191	Shared Neighborhood Hits	158
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET2_MOUSE
NC score	0.602835 (rank : 73)	θ value	4.59992e-12 (rank : 83)
Query Neighborhood Hits	582	Target Neighborhood Hits	193	Shared Neighborhood Hits	163
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET4_MOUSE
NC score	0.600218 (rank : 74)	θ value	2.28291e-11 (rank : 91)
Query Neighborhood Hits	582	Target Neighborhood Hits	180	Shared Neighborhood Hits	158
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

LTBP4_MOUSE
NC score	0.599606 (rank : 75)	θ value	1.58096e-12 (rank : 79)
Query Neighborhood Hits	582	Target Neighborhood Hits	607	Shared Neighborhood Hits	346
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

NET2_HUMAN
NC score	0.598363 (rank : 76)	θ value	1.33837e-11 (rank : 88)
Query Neighborhood Hits	582	Target Neighborhood Hits	194	Shared Neighborhood Hits	158
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

LAMA4_HUMAN
NC score	0.595024 (rank : 77)	θ value	4.59992e-12 (rank : 82)
Query Neighborhood Hits	582	Target Neighborhood Hits	708	Shared Neighborhood Hits	222
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

PGBM_MOUSE
NC score	0.593151 (rank : 78)	θ value	1.59853e-89 (rank : 3)
Query Neighborhood Hits	582	Target Neighborhood Hits	1073	Shared Neighborhood Hits	364
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

FBN3_HUMAN
NC score	0.591855 (rank : 79)	θ value	1.42992e-13 (rank : 71)
Query Neighborhood Hits	582	Target Neighborhood Hits	543	Shared Neighborhood Hits	368
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

NELL1_HUMAN
NC score	0.586851 (rank : 80)	θ value	0.00228821 (rank : 247)
Query Neighborhood Hits	582	Target Neighborhood Hits	451	Shared Neighborhood Hits	332
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

FBN2_HUMAN
NC score	0.586006 (rank : 81)	θ value	8.97725e-08 (rank : 121)
Query Neighborhood Hits	582	Target Neighborhood Hits	560	Shared Neighborhood Hits	375
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
NC score	0.585356 (rank : 82)	θ value	8.11959e-09 (rank : 113)
Query Neighborhood Hits	582	Target Neighborhood Hits	549	Shared Neighborhood Hits	371
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.584676 (rank : 83)	θ value	1.99992e-07 (rank : 124)
Query Neighborhood Hits	582	Target Neighborhood Hits	563	Shared Neighborhood Hits	365
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_HUMAN
NC score	0.584567 (rank : 84)	θ value	4.0297e-08 (rank : 115)
Query Neighborhood Hits	582	Target Neighborhood Hits	557	Shared Neighborhood Hits	370
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

EDIL3_MOUSE
NC score	0.583629 (rank : 85)	θ value	3.29651e-10 (rank : 100)
Query Neighborhood Hits	582	Target Neighborhood Hits	317	Shared Neighborhood Hits	266
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

SLIT1_HUMAN
NC score	0.581069 (rank : 86)	θ value	4.00176e-32 (rank : 7)
Query Neighborhood Hits	582	Target Neighborhood Hits	700	Shared Neighborhood Hits	344
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

KRA59_HUMAN
NC score	0.580484 (rank : 87)	θ value	0.00228821 (rank : 245)
Query Neighborhood Hits	582	Target Neighborhood Hits	310	Shared Neighborhood Hits	205
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LTBP2_HUMAN
NC score	0.580187 (rank : 88)	θ value	1.02475e-11 (rank : 87)
Query Neighborhood Hits	582	Target Neighborhood Hits	552	Shared Neighborhood Hits	351
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

PGBM_HUMAN
NC score	0.579733 (rank : 89)	θ value	3.22093e-90 (rank : 2)
Query Neighborhood Hits	582	Target Neighborhood Hits	1113	Shared Neighborhood Hits	373
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SLIT1_MOUSE
NC score	0.579646 (rank : 90)	θ value	6.38894e-30 (rank : 10)
Query Neighborhood Hits	582	Target Neighborhood Hits	715	Shared Neighborhood Hits	347
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

LTBP2_MOUSE
NC score	0.578275 (rank : 91)	θ value	5.62301e-10 (rank : 103)
Query Neighborhood Hits	582	Target Neighborhood Hits	617	Shared Neighborhood Hits	346
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

SLIT2_HUMAN
NC score	0.574943 (rank : 92)	θ value	1.33217e-27 (rank : 13)
Query Neighborhood Hits	582	Target Neighborhood Hits	708	Shared Neighborhood Hits	346
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

NET1_HUMAN
NC score	0.570792 (rank : 93)	θ value	1.74796e-11 (rank : 89)
Query Neighborhood Hits	582	Target Neighborhood Hits	149	Shared Neighborhood Hits	121
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NELL2_HUMAN
NC score	0.568966 (rank : 94)	θ value	0.00102713 (rank : 228)
Query Neighborhood Hits	582	Target Neighborhood Hits	449	Shared Neighborhood Hits	326
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

CREL1_HUMAN
NC score	0.568872 (rank : 95)	θ value	0.0113563 (rank : 271)
Query Neighborhood Hits	582	Target Neighborhood Hits	441	Shared Neighborhood Hits	246
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

KRA55_HUMAN
NC score	0.568163 (rank : 96)	θ value	0.00102713 (rank : 225)
Query Neighborhood Hits	582	Target Neighborhood Hits	257	Shared Neighborhood Hits	189
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

NET1_MOUSE
NC score	0.568021 (rank : 97)	θ value	6.00763e-12 (rank : 85)
Query Neighborhood Hits	582	Target Neighborhood Hits	151	Shared Neighborhood Hits	120
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

KRA58_HUMAN
NC score	0.567508 (rank : 98)	θ value	0.000602161 (rank : 210)
Query Neighborhood Hits	582	Target Neighborhood Hits	324	Shared Neighborhood Hits	228
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

NELL2_MOUSE
NC score	0.566903 (rank : 99)	θ value	0.000786445 (rank : 218)
Query Neighborhood Hits	582	Target Neighborhood Hits	436	Shared Neighborhood Hits	322
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

SLIT2_MOUSE
NC score	0.566705 (rank : 100)	θ value	2.12685e-25 (rank : 20)
Query Neighborhood Hits	582	Target Neighborhood Hits	684	Shared Neighborhood Hits	332
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

EDIL3_HUMAN
NC score	0.562635 (rank : 101)	θ value	5.62301e-10 (rank : 102)
Query Neighborhood Hits	582	Target Neighborhood Hits	292	Shared Neighborhood Hits	245
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

NAGPA_MOUSE
NC score	0.561399 (rank : 102)	θ value	0.21417 (rank : 346)
Query Neighborhood Hits	582	Target Neighborhood Hits	308	Shared Neighborhood Hits	255
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

TENX_HUMAN
NC score	0.559370 (rank : 103)	θ value	2.98157e-11 (rank : 94)
Query Neighborhood Hits	582	Target Neighborhood Hits	789	Shared Neighborhood Hits	360
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

SLIT3_MOUSE
NC score	0.558931 (rank : 104)	θ value	7.0802e-21 (rank : 40)
Query Neighborhood Hits	582	Target Neighborhood Hits	700	Shared Neighborhood Hits	340
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

LTBP3_HUMAN
NC score	0.558614 (rank : 105)	θ value	4.0297e-08 (rank : 116)
Query Neighborhood Hits	582	Target Neighborhood Hits	502	Shared Neighborhood Hits	330
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

TENA_HUMAN
NC score	0.555373 (rank : 106)	θ value	6.87365e-08 (rank : 119)
Query Neighborhood Hits	582	Target Neighborhood Hits	631	Shared Neighborhood Hits	342
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

NAGPA_HUMAN
NC score	0.552841 (rank : 107)	θ value	0.0330416 (rank : 303)
Query Neighborhood Hits	582	Target Neighborhood Hits	282	Shared Neighborhood Hits	232
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

TENA_MOUSE
NC score	0.551840 (rank : 108)	θ value	1.9326e-10 (rank : 98)
Query Neighborhood Hits	582	Target Neighborhood Hits	596	Shared Neighborhood Hits	333
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

LTBP3_MOUSE
NC score	0.551415 (rank : 109)	θ value	1.43324e-05 (rank : 164)
Query Neighborhood Hits	582	Target Neighborhood Hits	475	Shared Neighborhood Hits	335
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NRX1A_HUMAN
NC score	0.551171 (rank : 110)	θ value	2.34606e-32 (rank : 6)
Query Neighborhood Hits	582	Target Neighborhood Hits	170	Shared Neighborhood Hits	137
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

KR104_HUMAN
NC score	0.549588 (rank : 111)	θ value	2.28291e-11 (rank : 90)
Query Neighborhood Hits	582	Target Neighborhood Hits	313	Shared Neighborhood Hits	232
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

CREL1_MOUSE
NC score	0.549559 (rank : 112)	θ value	0.00509761 (rank : 258)
Query Neighborhood Hits	582	Target Neighborhood Hits	524	Shared Neighborhood Hits	256
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

NRX1A_MOUSE
NC score	0.548741 (rank : 113)	θ value	3.3877e-31 (rank : 9)
Query Neighborhood Hits	582	Target Neighborhood Hits	164	Shared Neighborhood Hits	136
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

SLIT3_HUMAN
NC score	0.548471 (rank : 114)	θ value	1.2077e-20 (rank : 41)
Query Neighborhood Hits	582	Target Neighborhood Hits	682	Shared Neighborhood Hits	322
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

NRX3A_HUMAN
NC score	0.545615 (rank : 115)	θ value	7.04741e-37 (rank : 5)
Query Neighborhood Hits	582	Target Neighborhood Hits	164	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

CUBN_HUMAN
NC score	0.543390 (rank : 116)	θ value	1.09739e-05 (rank : 153)
Query Neighborhood Hits	582	Target Neighborhood Hits	482	Shared Neighborhood Hits	323
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

KRA57_HUMAN
NC score	0.542564 (rank : 117)	θ value	0.00035302 (rank : 204)
Query Neighborhood Hits	582	Target Neighborhood Hits	269	Shared Neighborhood Hits	199
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

ZAN_MOUSE
NC score	0.540253 (rank : 118)	θ value	3.64472e-09 (rank : 110)
Query Neighborhood Hits	582	Target Neighborhood Hits	808	Shared Neighborhood Hits	384
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

GAS6_MOUSE
NC score	0.537917 (rank : 119)	θ value	1.09739e-05 (rank : 154)
Query Neighborhood Hits	582	Target Neighborhood Hits	343	Shared Neighborhood Hits	277
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

LTB1L_HUMAN
NC score	0.536780 (rank : 120)	θ value	1.09739e-05 (rank : 156)
Query Neighborhood Hits	582	Target Neighborhood Hits	553	Shared Neighborhood Hits	330
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.536754 (rank : 121)	θ value	1.09739e-05 (rank : 157)
Query Neighborhood Hits	582	Target Neighborhood Hits	502	Shared Neighborhood Hits	319
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

KR107_HUMAN
NC score	0.535318 (rank : 122)	θ value	3.41135e-07 (rank : 126)
Query Neighborhood Hits	582	Target Neighborhood Hits	330	Shared Neighborhood Hits	241
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR106_HUMAN
NC score	0.534832 (rank : 123)	θ value	1.99992e-07 (rank : 125)
Query Neighborhood Hits	582	Target Neighborhood Hits	347	Shared Neighborhood Hits	250
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

LTB1L_MOUSE
NC score	0.534266 (rank : 124)	θ value	1.43324e-05 (rank : 162)
Query Neighborhood Hits	582	Target Neighborhood Hits	514	Shared Neighborhood Hits	334
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.532263 (rank : 125)	θ value	1.43324e-05 (rank : 163)
Query Neighborhood Hits	582	Target Neighborhood Hits	479	Shared Neighborhood Hits	314
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

GAS6_HUMAN
NC score	0.531575 (rank : 126)	θ value	0.00020696 (rank : 191)
Query Neighborhood Hits	582	Target Neighborhood Hits	348	Shared Neighborhood Hits	275
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

CUBN_MOUSE
NC score	0.531387 (rank : 127)	θ value	4.1701e-05 (rank : 174)
Query Neighborhood Hits	582	Target Neighborhood Hits	477	Shared Neighborhood Hits	309
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

PROS_HUMAN
NC score	0.527604 (rank : 128)	θ value	0.0193708 (rank : 289)
Query Neighborhood Hits	582	Target Neighborhood Hits	340	Shared Neighborhood Hits	279
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

KRA54_HUMAN
NC score	0.527282 (rank : 129)	θ value	0.00020696 (rank : 193)
Query Neighborhood Hits	582	Target Neighborhood Hits	270	Shared Neighborhood Hits	186
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

EGFL7_HUMAN
NC score	0.527069 (rank : 130)	θ value	2.44474e-05 (rank : 167)
Query Neighborhood Hits	582	Target Neighborhood Hits	325	Shared Neighborhood Hits	259
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

PROS_MOUSE
NC score	0.522934 (rank : 131)	θ value	0.000121331 (rank : 185)
Query Neighborhood Hits	582	Target Neighborhood Hits	330	Shared Neighborhood Hits	265
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

NRX2A_HUMAN
NC score	0.514032 (rank : 132)	θ value	2.76489e-41 (rank : 4)
Query Neighborhood Hits	582	Target Neighborhood Hits	614	Shared Neighborhood Hits	168
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

C1QR1_HUMAN
NC score	0.506505 (rank : 133)	θ value	0.00020696 (rank : 190)
Query Neighborhood Hits	582	Target Neighborhood Hits	493	Shared Neighborhood Hits	277
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

EGFL7_MOUSE
NC score	0.504894 (rank : 134)	θ value	0.0148317 (rank : 278)
Query Neighborhood Hits	582	Target Neighborhood Hits	287	Shared Neighborhood Hits	237
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

LRP1_HUMAN
NC score	0.504891 (rank : 135)	θ value	0.00665767 (rank : 264)
Query Neighborhood Hits	582	Target Neighborhood Hits	617	Shared Neighborhood Hits	371
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

ATRN_MOUSE
NC score	0.503513 (rank : 136)	θ value	0.00102713 (rank : 220)
Query Neighborhood Hits	582	Target Neighborhood Hits	519	Shared Neighborhood Hits	268
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

SCUB3_MOUSE
NC score	0.502650 (rank : 137)	θ value	0.0330416 (rank : 304)
Query Neighborhood Hits	582	Target Neighborhood Hits	442	Shared Neighborhood Hits	276
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.501821 (rank : 138)	θ value	0.0113563 (rank : 274)
Query Neighborhood Hits	582	Target Neighborhood Hits	428	Shared Neighborhood Hits	267
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ATRN_HUMAN
NC score	0.500651 (rank : 139)	θ value	0.000786445 (rank : 215)
Query Neighborhood Hits	582	Target Neighborhood Hits	525	Shared Neighborhood Hits	267
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

C1QR1_MOUSE
NC score	0.499854 (rank : 140)	θ value	0.00102713 (rank : 221)
Query Neighborhood Hits	582	Target Neighborhood Hits	342	Shared Neighborhood Hits	248
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

LRP1B_HUMAN
NC score	0.498431 (rank : 141)	θ value	0.000270298 (rank : 198)
Query Neighborhood Hits	582	Target Neighborhood Hits	602	Shared Neighborhood Hits	368
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FBLN2_HUMAN
NC score	0.496981 (rank : 142)	θ value	0.0113563 (rank : 272)
Query Neighborhood Hits	582	Target Neighborhood Hits	392	Shared Neighborhood Hits	262
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

NID2_HUMAN
NC score	0.495665 (rank : 143)	θ value	0.000602161 (rank : 211)
Query Neighborhood Hits	582	Target Neighborhood Hits	456	Shared Neighborhood Hits	272
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

LRP1B_MOUSE
NC score	0.494667 (rank : 144)	θ value	0.00102713 (rank : 226)
Query Neighborhood Hits	582	Target Neighborhood Hits	606	Shared Neighborhood Hits	370
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

KRA52_HUMAN
NC score	0.493061 (rank : 145)	θ value	2.21117e-06 (rank : 139)
Query Neighborhood Hits	582	Target Neighborhood Hits	236	Shared Neighborhood Hits	174
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

FBLN2_MOUSE
NC score	0.492407 (rank : 146)	θ value	0.000158464 (rank : 189)
Query Neighborhood Hits	582	Target Neighborhood Hits	505	Shared Neighborhood Hits	291
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

TSP4_MOUSE
NC score	0.489520 (rank : 147)	θ value	0.000121331 (rank : 187)
Query Neighborhood Hits	582	Target Neighborhood Hits	276	Shared Neighborhood Hits	239
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

KR510_HUMAN
NC score	0.488363 (rank : 148)	θ value	1.69304e-06 (rank : 137)
Query Neighborhood Hits	582	Target Neighborhood Hits	217	Shared Neighborhood Hits	153
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

TRBM_HUMAN
NC score	0.485467 (rank : 149)	θ value	0.00665767 (rank : 266)
Query Neighborhood Hits	582	Target Neighborhood Hits	339	Shared Neighborhood Hits	249
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

COMP_MOUSE
NC score	0.484119 (rank : 150)	θ value	7.1131e-05 (rank : 178)
Query Neighborhood Hits	582	Target Neighborhood Hits	290	Shared Neighborhood Hits	233
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

TSP4_HUMAN
NC score	0.483652 (rank : 151)	θ value	0.000786445 (rank : 219)
Query Neighborhood Hits	582	Target Neighborhood Hits	277	Shared Neighborhood Hits	231
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

NID1_HUMAN
NC score	0.483575 (rank : 152)	θ value	0.0252991 (rank : 296)
Query Neighborhood Hits	582	Target Neighborhood Hits	329	Shared Neighborhood Hits	257
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_MOUSE
NC score	0.482468 (rank : 153)	θ value	0.000461057 (rank : 209)
Query Neighborhood Hits	582	Target Neighborhood Hits	338	Shared Neighborhood Hits	255
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

KR511_HUMAN
NC score	0.480809 (rank : 154)	θ value	0.0961366 (rank : 327)
Query Neighborhood Hits	582	Target Neighborhood Hits	231	Shared Neighborhood Hits	170
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

FBLN1_MOUSE
NC score	0.480233 (rank : 155)	θ value	0.163984 (rank : 340)
Query Neighborhood Hits	582	Target Neighborhood Hits	329	Shared Neighborhood Hits	243
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

KRA56_HUMAN
NC score	0.478795 (rank : 156)	θ value	0.21417 (rank : 345)
Query Neighborhood Hits	582	Target Neighborhood Hits	207	Shared Neighborhood Hits	164
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KR101_HUMAN
NC score	0.478581 (rank : 157)	θ value	0.00175202 (rank : 241)
Query Neighborhood Hits	582	Target Neighborhood Hits	261	Shared Neighborhood Hits	185
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

CRIM1_HUMAN
NC score	0.478374 (rank : 158)	θ value	0.000158464 (rank : 188)
Query Neighborhood Hits	582	Target Neighborhood Hits	362	Shared Neighborhood Hits	227
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

NID1_MOUSE
NC score	0.477295 (rank : 159)	θ value	0.0431538 (rank : 314)
Query Neighborhood Hits	582	Target Neighborhood Hits	335	Shared Neighborhood Hits	250
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TEFF2_MOUSE
NC score	0.475939 (rank : 160)	θ value	4.43474e-23 (rank : 32)
Query Neighborhood Hits	582	Target Neighborhood Hits	214	Shared Neighborhood Hits	185
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

ITB6_MOUSE
NC score	0.472721 (rank : 161)	θ value	1.09739e-05 (rank : 155)
Query Neighborhood Hits	582	Target Neighborhood Hits	341	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

FBLN1_HUMAN
NC score	0.472662 (rank : 162)	θ value	0.62314 (rank : 390)
Query Neighborhood Hits	582	Target Neighborhood Hits	324	Shared Neighborhood Hits	248
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

EGFL8_MOUSE
NC score	0.472506 (rank : 163)	θ value	5.27518 (rank : 514)
Query Neighborhood Hits	582	Target Neighborhood Hits	266	Shared Neighborhood Hits	217
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

TEFF2_HUMAN
NC score	0.472503 (rank : 164)	θ value	4.43474e-23 (rank : 31)
Query Neighborhood Hits	582	Target Neighborhood Hits	211	Shared Neighborhood Hits	182
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

HHIP_HUMAN
NC score	0.471882 (rank : 165)	θ value	4.03905 (rank : 495)
Query Neighborhood Hits	582	Target Neighborhood Hits	249	Shared Neighborhood Hits	216
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

EGFL8_HUMAN
NC score	0.470208 (rank : 166)	θ value	0.813845 (rank : 398)
Query Neighborhood Hits	582	Target Neighborhood Hits	270	Shared Neighborhood Hits	214
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

UROM_HUMAN
NC score	0.467846 (rank : 167)	θ value	0.0961366 (rank : 329)
Query Neighborhood Hits	582	Target Neighborhood Hits	284	Shared Neighborhood Hits	231
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ITB5_MOUSE
NC score	0.466867 (rank : 168)	θ value	0.000121331 (rank : 184)
Query Neighborhood Hits	582	Target Neighborhood Hits	329	Shared Neighborhood Hits	264
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

TRBM_MOUSE
NC score	0.466792 (rank : 169)	θ value	0.47712 (rank : 383)
Query Neighborhood Hits	582	Target Neighborhood Hits	361	Shared Neighborhood Hits	245
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

EGF_MOUSE
NC score	0.465649 (rank : 170)	θ value	0.00509761 (rank : 259)
Query Neighborhood Hits	582	Target Neighborhood Hits	358	Shared Neighborhood Hits	272
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

MFGM_MOUSE
NC score	0.464139 (rank : 171)	θ value	1.17247e-07 (rank : 123)
Query Neighborhood Hits	582	Target Neighborhood Hits	233	Shared Neighborhood Hits	198
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

COMP_HUMAN
NC score	0.459579 (rank : 172)	θ value	0.00102713 (rank : 222)
Query Neighborhood Hits	582	Target Neighborhood Hits	258	Shared Neighborhood Hits	214
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CNTP4_MOUSE
NC score	0.459232 (rank : 173)	θ value	1.24977e-17 (rank : 53)
Query Neighborhood Hits	582	Target Neighborhood Hits	193	Shared Neighborhood Hits	141
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

ITB7_MOUSE
NC score	0.458788 (rank : 174)	θ value	0.00035302 (rank : 203)
Query Neighborhood Hits	582	Target Neighborhood Hits	277	Shared Neighborhood Hits	232
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB2_MOUSE
NC score	0.458290 (rank : 175)	θ value	0.00102713 (rank : 224)
Query Neighborhood Hits	582	Target Neighborhood Hits	326	Shared Neighborhood Hits	268
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

UROM_MOUSE
NC score	0.457555 (rank : 176)	θ value	0.279714 (rank : 359)
Query Neighborhood Hits	582	Target Neighborhood Hits	276	Shared Neighborhood Hits	230
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ITB7_HUMAN
NC score	0.457507 (rank : 177)	θ value	0.0431538 (rank : 311)
Query Neighborhood Hits	582	Target Neighborhood Hits	290	Shared Neighborhood Hits	237
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB6_HUMAN
NC score	0.456803 (rank : 178)	θ value	0.000270298 (rank : 196)
Query Neighborhood Hits	582	Target Neighborhood Hits	318	Shared Neighborhood Hits	252
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

CNTP2_MOUSE
NC score	0.456712 (rank : 179)	θ value	4.16044e-13 (rank : 73)
Query Neighborhood Hits	582	Target Neighborhood Hits	194	Shared Neighborhood Hits	143
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

KR171_HUMAN
NC score	0.456034 (rank : 180)	θ value	0.163984 (rank : 342)
Query Neighborhood Hits	582	Target Neighborhood Hits	144	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

CNTP2_HUMAN
NC score	0.455897 (rank : 181)	θ value	5.8054e-15 (rank : 63)
Query Neighborhood Hits	582	Target Neighborhood Hits	199	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP4_HUMAN
NC score	0.455163 (rank : 182)	θ value	1.52774e-15 (rank : 61)
Query Neighborhood Hits	582	Target Neighborhood Hits	187	Shared Neighborhood Hits	126
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

FBLN4_HUMAN
NC score	0.453217 (rank : 183)	θ value	0.47712 (rank : 376)
Query Neighborhood Hits	582	Target Neighborhood Hits	278	Shared Neighborhood Hits	222
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

ITB5_HUMAN
NC score	0.453090 (rank : 184)	θ value	1.87187e-05 (rank : 166)
Query Neighborhood Hits	582	Target Neighborhood Hits	310	Shared Neighborhood Hits	250
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

FBLN5_HUMAN
NC score	0.452525 (rank : 185)	θ value	0.163984 (rank : 341)
Query Neighborhood Hits	582	Target Neighborhood Hits	329	Shared Neighborhood Hits	245
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
NC score	0.447313 (rank : 186)	θ value	0.0193708 (rank : 285)
Query Neighborhood Hits	582	Target Neighborhood Hits	317	Shared Neighborhood Hits	234
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

KR102_HUMAN
NC score	0.446266 (rank : 187)	θ value	0.00228821 (rank : 244)
Query Neighborhood Hits	582	Target Neighborhood Hits	264	Shared Neighborhood Hits	193
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR105_HUMAN
NC score	0.446242 (rank : 188)	θ value	0.00509761 (rank : 260)
Query Neighborhood Hits	582	Target Neighborhood Hits	271	Shared Neighborhood Hits	201
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

CSPG3_MOUSE
NC score	0.445393 (rank : 189)	θ value	0.000461057 (rank : 207)
Query Neighborhood Hits	582	Target Neighborhood Hits	657	Shared Neighborhood Hits	275
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TSP3_MOUSE
NC score	0.444979 (rank : 190)	θ value	0.00228821 (rank : 248)
Query Neighborhood Hits	582	Target Neighborhood Hits	247	Shared Neighborhood Hits	202
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

FBLN4_MOUSE
NC score	0.444947 (rank : 191)	θ value	1.38821 (rank : 432)
Query Neighborhood Hits	582	Target Neighborhood Hits	270	Shared Neighborhood Hits	214
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

ITB3_HUMAN
NC score	0.444438 (rank : 192)	θ value	8.40245e-06 (rank : 152)
Query Neighborhood Hits	582	Target Neighborhood Hits	325	Shared Neighborhood Hits	262
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

CNTP3_HUMAN
NC score	0.444403 (rank : 193)	θ value	1.29331e-14 (rank : 66)
Query Neighborhood Hits	582	Target Neighborhood Hits	195	Shared Neighborhood Hits	133
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CELR3_HUMAN
NC score	0.444286 (rank : 194)	θ value	4.73814e-25 (rank : 22)
Query Neighborhood Hits	582	Target Neighborhood Hits	680	Shared Neighborhood Hits	328
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

HHIP_MOUSE
NC score	0.442902 (rank : 195)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	582	Target Neighborhood Hits	219	Shared Neighborhood Hits	194
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

CELR3_MOUSE
NC score	0.442761 (rank : 196)	θ value	2.12685e-25 (rank : 19)
Query Neighborhood Hits	582	Target Neighborhood Hits	687	Shared Neighborhood Hits	331
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CELR2_HUMAN
NC score	0.442760 (rank : 197)	θ value	4.28545e-26 (rank : 17)
Query Neighborhood Hits	582	Target Neighborhood Hits	657	Shared Neighborhood Hits	320
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

KR109_HUMAN
NC score	0.441321 (rank : 198)	θ value	0.000270298 (rank : 197)
Query Neighborhood Hits	582	Target Neighborhood Hits	226	Shared Neighborhood Hits	171
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

CSPG2_MOUSE
NC score	0.439053 (rank : 199)	θ value	4.1701e-05 (rank : 173)
Query Neighborhood Hits	582	Target Neighborhood Hits	711	Shared Neighborhood Hits	274
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
NC score	0.438715 (rank : 200)	θ value	5.44631e-05 (rank : 177)
Query Neighborhood Hits	582	Target Neighborhood Hits	676	Shared Neighborhood Hits	269
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TSP3_HUMAN
NC score	0.435676 (rank : 201)	θ value	0.00020696 (rank : 195)
Query Neighborhood Hits	582	Target Neighborhood Hits	250	Shared Neighborhood Hits	198
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

CSPG2_HUMAN
NC score	0.434423 (rank : 202)	θ value	3.19293e-05 (rank : 170)
Query Neighborhood Hits	582	Target Neighborhood Hits	681	Shared Neighborhood Hits	269
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

FBLN3_HUMAN
NC score	0.432583 (rank : 203)	θ value	0.125558 (rank : 333)
Query Neighborhood Hits	582	Target Neighborhood Hits	293	Shared Neighborhood Hits	227
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FRAS1_HUMAN
NC score	0.430469 (rank : 204)	θ value	1.9326e-10 (rank : 97)
Query Neighborhood Hits	582	Target Neighborhood Hits	759	Shared Neighborhood Hits	303
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

EMR1_HUMAN
NC score	0.429364 (rank : 205)	θ value	0.00035302 (rank : 201)
Query Neighborhood Hits	582	Target Neighborhood Hits	382	Shared Neighborhood Hits	236
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

ITB3_MOUSE
NC score	0.428889 (rank : 206)	θ value	2.44474e-05 (rank : 169)
Query Neighborhood Hits	582	Target Neighborhood Hits	319	Shared Neighborhood Hits	249
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

FSTL3_HUMAN
NC score	0.427513 (rank : 207)	θ value	7.58209e-15 (rank : 64)
Query Neighborhood Hits	582	Target Neighborhood Hits	162	Shared Neighborhood Hits	142
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FATH_HUMAN
NC score	0.427509 (rank : 208)	θ value	8.91499e-32 (rank : 8)
Query Neighborhood Hits	582	Target Neighborhood Hits	570	Shared Neighborhood Hits	303
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

ITB2_HUMAN
NC score	0.426250 (rank : 209)	θ value	0.00134147 (rank : 234)
Query Neighborhood Hits	582	Target Neighborhood Hits	282	Shared Neighborhood Hits	233
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

EGF_HUMAN
NC score	0.423297 (rank : 210)	θ value	0.62314 (rank : 388)
Query Neighborhood Hits	582	Target Neighborhood Hits	343	Shared Neighborhood Hits	247
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

CELR1_HUMAN
NC score	0.421256 (rank : 211)	θ value	4.29542e-18 (rank : 52)
Query Neighborhood Hits	582	Target Neighborhood Hits	613	Shared Neighborhood Hits	296
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CNTP1_HUMAN
NC score	0.420509 (rank : 212)	θ value	7.59969e-07 (rank : 134)
Query Neighborhood Hits	582	Target Neighborhood Hits	196	Shared Neighborhood Hits	127
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

KR10C_HUMAN
NC score	0.419691 (rank : 213)	θ value	0.47712 (rank : 377)
Query Neighborhood Hits	582	Target Neighborhood Hits	219	Shared Neighborhood Hits	170
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR108_HUMAN
NC score	0.419384 (rank : 214)	θ value	0.0431538 (rank : 312)
Query Neighborhood Hits	582	Target Neighborhood Hits	226	Shared Neighborhood Hits	167
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

ITB1_MOUSE
NC score	0.419314 (rank : 215)	θ value	0.0252991 (rank : 295)
Query Neighborhood Hits	582	Target Neighborhood Hits	283	Shared Neighborhood Hits	219
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

FRAS1_MOUSE
NC score	0.418809 (rank : 216)	θ value	8.67504e-11 (rank : 95)
Query Neighborhood Hits	582	Target Neighborhood Hits	747	Shared Neighborhood Hits	292
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ITB1_HUMAN
NC score	0.418469 (rank : 217)	θ value	0.0563607 (rank : 316)
Query Neighborhood Hits	582	Target Neighborhood Hits	298	Shared Neighborhood Hits	232
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

CELR1_MOUSE
NC score	0.418449 (rank : 218)	θ value	1.38178e-16 (rank : 55)
Query Neighborhood Hits	582	Target Neighborhood Hits	617	Shared Neighborhood Hits	301
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

FBLN3_MOUSE
NC score	0.418368 (rank : 219)	θ value	0.279714 (rank : 353)
Query Neighborhood Hits	582	Target Neighborhood Hits	279	Shared Neighborhood Hits	214
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

MATN2_HUMAN
NC score	0.418056 (rank : 220)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	582	Target Neighborhood Hits	365	Shared Neighborhood Hits	234
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

SUSD1_HUMAN
NC score	0.417479 (rank : 221)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	582	Target Neighborhood Hits	285	Shared Neighborhood Hits	202
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

KR10B_HUMAN
NC score	0.417387 (rank : 222)	θ value	0.00134147 (rank : 235)
Query Neighborhood Hits	582	Target Neighborhood Hits	269	Shared Neighborhood Hits	186
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

CNTP1_MOUSE
NC score	0.416668 (rank : 223)	θ value	3.77169e-06 (rank : 144)
Query Neighborhood Hits	582	Target Neighborhood Hits	183	Shared Neighborhood Hits	118
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

PCSK5_MOUSE
NC score	0.416422 (rank : 224)	θ value	0.00035302 (rank : 205)
Query Neighborhood Hits	582	Target Neighborhood Hits	613	Shared Neighborhood Hits	298
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

CELR2_MOUSE
NC score	0.416168 (rank : 225)	θ value	3.17815e-21 (rank : 38)
Query Neighborhood Hits	582	Target Neighborhood Hits	584	Shared Neighborhood Hits	292
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

FST_MOUSE
NC score	0.412880 (rank : 226)	θ value	4.57862e-28 (rank : 11)
Query Neighborhood Hits	582	Target Neighborhood Hits	146	Shared Neighborhood Hits	136
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FSTL3_MOUSE
NC score	0.410318 (rank : 227)	θ value	4.91457e-14 (rank : 68)
Query Neighborhood Hits	582	Target Neighborhood Hits	152	Shared Neighborhood Hits	139
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

LRP2_HUMAN
NC score	0.409174 (rank : 228)	θ value	0.365318 (rank : 366)
Query Neighborhood Hits	582	Target Neighborhood Hits	573	Shared Neighborhood Hits	362
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

MATN2_MOUSE
NC score	0.406062 (rank : 229)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	582	Target Neighborhood Hits	356	Shared Neighborhood Hits	234
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

EMR2_HUMAN
NC score	0.405639 (rank : 230)	θ value	0.279714 (rank : 352)
Query Neighborhood Hits	582	Target Neighborhood Hits	345	Shared Neighborhood Hits	218
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

ITB4_HUMAN
NC score	0.405590 (rank : 231)	θ value	0.0148317 (rank : 281)
Query Neighborhood Hits	582	Target Neighborhood Hits	458	Shared Neighborhood Hits	251
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

PROZ_MOUSE
NC score	0.403837 (rank : 232)	θ value	0.00390308 (rank : 256)
Query Neighborhood Hits	582	Target Neighborhood Hits	410	Shared Neighborhood Hits	228
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_HUMAN
NC score	0.402757 (rank : 233)	θ value	0.000121331 (rank : 186)
Query Neighborhood Hits	582	Target Neighborhood Hits	422	Shared Neighborhood Hits	236
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FST_HUMAN
NC score	0.401976 (rank : 234)	θ value	1.02001e-27 (rank : 12)
Query Neighborhood Hits	582	Target Neighborhood Hits	129	Shared Neighborhood Hits	118
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

CD97_HUMAN
NC score	0.401639 (rank : 235)	θ value	1.06291 (rank : 415)
Query Neighborhood Hits	582	Target Neighborhood Hits	353	Shared Neighborhood Hits	224
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

GRN_MOUSE
NC score	0.399116 (rank : 236)	θ value	0.0330416 (rank : 299)
Query Neighborhood Hits	582	Target Neighborhood Hits	248	Shared Neighborhood Hits	202
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

GRN_HUMAN
NC score	0.396088 (rank : 237)	θ value	0.00298849 (rank : 250)
Query Neighborhood Hits	582	Target Neighborhood Hits	268	Shared Neighborhood Hits	201
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

EMR1_MOUSE
NC score	0.395162 (rank : 238)	θ value	0.47712 (rank : 374)
Query Neighborhood Hits	582	Target Neighborhood Hits	349	Shared Neighborhood Hits	219
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

VLDLR_HUMAN
NC score	0.386776 (rank : 239)	θ value	0.00102713 (rank : 231)
Query Neighborhood Hits	582	Target Neighborhood Hits	383	Shared Neighborhood Hits	261
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

TENR_MOUSE
NC score	0.385315 (rank : 240)	θ value	0.0330416 (rank : 305)
Query Neighborhood Hits	582	Target Neighborhood Hits	531	Shared Neighborhood Hits	289
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

VLDLR_MOUSE
NC score	0.381728 (rank : 241)	θ value	0.00102713 (rank : 232)
Query Neighborhood Hits	582	Target Neighborhood Hits	360	Shared Neighborhood Hits	248
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LDLR_HUMAN
NC score	0.381482 (rank : 242)	θ value	0.00665767 (rank : 263)
Query Neighborhood Hits	582	Target Neighborhood Hits	375	Shared Neighborhood Hits	263
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

TENR_HUMAN
NC score	0.379600 (rank : 243)	θ value	0.0148317 (rank : 284)
Query Neighborhood Hits	582	Target Neighborhood Hits	526	Shared Neighborhood Hits	286
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

SSPO_MOUSE
NC score	0.373078 (rank : 244)	θ value	2.21117e-06 (rank : 140)
Query Neighborhood Hits	582	Target Neighborhood Hits	800	Shared Neighborhood Hits	351
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

CD248_HUMAN
NC score	0.368907 (rank : 245)	θ value	0.62314 (rank : 385)
Query Neighborhood Hits	582	Target Neighborhood Hits	679	Shared Neighborhood Hits	245
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

LRP8_MOUSE
NC score	0.368580 (rank : 246)	θ value	0.00102713 (rank : 227)
Query Neighborhood Hits	582	Target Neighborhood Hits	385	Shared Neighborhood Hits	247
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LDLR_MOUSE
NC score	0.365675 (rank : 247)	θ value	0.0193708 (rank : 287)
Query Neighborhood Hits	582	Target Neighborhood Hits	382	Shared Neighborhood Hits	259
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

CD248_MOUSE
NC score	0.364785 (rank : 248)	θ value	0.62314 (rank : 386)
Query Neighborhood Hits	582	Target Neighborhood Hits	578	Shared Neighborhood Hits	219
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ZAN_HUMAN
NC score	0.356941 (rank : 249)	θ value	0.000602161 (rank : 214)
Query Neighborhood Hits	582	Target Neighborhood Hits	679	Shared Neighborhood Hits	300
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

KR10A_HUMAN
NC score	0.355062 (rank : 250)	θ value	0.0330416 (rank : 301)
Query Neighborhood Hits	582	Target Neighborhood Hits	232	Shared Neighborhood Hits	169
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

ITB8_HUMAN
NC score	0.354481 (rank : 251)	θ value	0.62314 (rank : 391)
Query Neighborhood Hits	582	Target Neighborhood Hits	280	Shared Neighborhood Hits	218
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

CFC1_HUMAN
NC score	0.353691 (rank : 252)	θ value	4.03905 (rank : 493)
Query Neighborhood Hits	582	Target Neighborhood Hits	148	Shared Neighborhood Hits	140
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

KRA11_HUMAN
NC score	0.350822 (rank : 253)	θ value	0.0563607 (rank : 317)
Query Neighborhood Hits	582	Target Neighborhood Hits	155	Shared Neighborhood Hits	123
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA47_HUMAN
NC score	0.348916 (rank : 254)	θ value	0.00509761 (rank : 261)
Query Neighborhood Hits	582	Target Neighborhood Hits	204	Shared Neighborhood Hits	150
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

TSP1_MOUSE
NC score	0.346115 (rank : 255)	θ value	0.0563607 (rank : 319)
Query Neighborhood Hits	582	Target Neighborhood Hits	396	Shared Neighborhood Hits	252
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

LRP8_HUMAN
NC score	0.345490 (rank : 256)	θ value	1.38821 (rank : 435)
Query Neighborhood Hits	582	Target Neighborhood Hits	346	Shared Neighborhood Hits	229
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

KR103_HUMAN
NC score	0.344704 (rank : 257)	θ value	0.0330416 (rank : 300)
Query Neighborhood Hits	582	Target Neighborhood Hits	212	Shared Neighborhood Hits	155
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

TSP1_HUMAN
NC score	0.339799 (rank : 258)	θ value	0.21417 (rank : 351)
Query Neighborhood Hits	582	Target Neighborhood Hits	389	Shared Neighborhood Hits	250
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

MATN4_HUMAN
NC score	0.339263 (rank : 259)	θ value	0.163984 (rank : 343)
Query Neighborhood Hits	582	Target Neighborhood Hits	287	Shared Neighborhood Hits	199
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

KRA13_HUMAN
NC score	0.336140 (rank : 260)	θ value	0.0736092 (rank : 322)
Query Neighborhood Hits	582	Target Neighborhood Hits	144	Shared Neighborhood Hits	114
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

ELTD1_MOUSE
NC score	0.335817 (rank : 261)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	582	Target Neighborhood Hits	288	Shared Neighborhood Hits	183
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

KR414_HUMAN
NC score	0.332038 (rank : 262)	θ value	1.38821 (rank : 434)
Query Neighborhood Hits	582	Target Neighborhood Hits	199	Shared Neighborhood Hits	148
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

CD97_MOUSE
NC score	0.326917 (rank : 263)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	582	Target Neighborhood Hits	295	Shared Neighborhood Hits	186
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

MUC5B_HUMAN
NC score	0.325968 (rank : 264)	θ value	0.00228821 (rank : 246)
Query Neighborhood Hits	582	Target Neighborhood Hits	1020	Shared Neighborhood Hits	305
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TENN_MOUSE
NC score	0.325025 (rank : 265)	θ value	0.00298849 (rank : 253)
Query Neighborhood Hits	582	Target Neighborhood Hits	484	Shared Neighborhood Hits	257
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

MATN3_HUMAN
NC score	0.324992 (rank : 266)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	582	Target Neighborhood Hits	268	Shared Neighborhood Hits	184
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
NC score	0.323199 (rank : 267)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	582	Target Neighborhood Hits	261	Shared Neighborhood Hits	187
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

TDGF1_MOUSE
NC score	0.323155 (rank : 268)	θ value	1.81305 (rank : 454)
Query Neighborhood Hits	582	Target Neighborhood Hits	146	Shared Neighborhood Hits	139
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

KRA94_HUMAN
NC score	0.319950 (rank : 269)	θ value	1.06291 (rank : 420)
Query Neighborhood Hits	582	Target Neighborhood Hits	204	Shared Neighborhood Hits	153
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA45_HUMAN
NC score	0.319157 (rank : 270)	θ value	2.36792 (rank : 461)
Query Neighborhood Hits	582	Target Neighborhood Hits	194	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

HMCN1_HUMAN
NC score	0.318534 (rank : 271)	θ value	0.00390308 (rank : 254)
Query Neighborhood Hits	582	Target Neighborhood Hits	983	Shared Neighborhood Hits	285
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

LRP4_MOUSE
NC score	0.317685 (rank : 272)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	582	Target Neighborhood Hits	351	Shared Neighborhood Hits	233
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

HABP2_HUMAN
NC score	0.317206 (rank : 273)	θ value	8.40245e-06 (rank : 151)
Query Neighborhood Hits	582	Target Neighborhood Hits	431	Shared Neighborhood Hits	249
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
NC score	0.317008 (rank : 274)	θ value	0.000121331 (rank : 183)
Query Neighborhood Hits	582	Target Neighborhood Hits	445	Shared Neighborhood Hits	257
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LRP4_HUMAN
NC score	0.316637 (rank : 275)	θ value	5.27518 (rank : 520)
Query Neighborhood Hits	582	Target Neighborhood Hits	355	Shared Neighborhood Hits	234
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

CFC1_MOUSE
NC score	0.316232 (rank : 276)	θ value	8.99809 (rank : 569)
Query Neighborhood Hits	582	Target Neighborhood Hits	125	Shared Neighborhood Hits	122
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

MATN4_MOUSE
NC score	0.315987 (rank : 277)	θ value	0.00390308 (rank : 255)
Query Neighborhood Hits	582	Target Neighborhood Hits	277	Shared Neighborhood Hits	190
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

NFX1_HUMAN
NC score	0.315104 (rank : 278)	θ value	0.125558 (rank : 337)
Query Neighborhood Hits	582	Target Neighborhood Hits	405	Shared Neighborhood Hits	167
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

TENN_HUMAN
NC score	0.313979 (rank : 279)	θ value	0.21417 (rank : 350)
Query Neighborhood Hits	582	Target Neighborhood Hits	453	Shared Neighborhood Hits	260
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

FAT2_HUMAN
NC score	0.310730 (rank : 280)	θ value	1.68911e-14 (rank : 67)
Query Neighborhood Hits	582	Target Neighborhood Hits	507	Shared Neighborhood Hits	233
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

RECK_HUMAN
NC score	0.310304 (rank : 281)	θ value	5.62301e-10 (rank : 104)
Query Neighborhood Hits	582	Target Neighborhood Hits	189	Shared Neighborhood Hits	157
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

KRA44_HUMAN
NC score	0.310203 (rank : 282)	θ value	0.0330416 (rank : 302)
Query Neighborhood Hits	582	Target Neighborhood Hits	162	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

TSP2_MOUSE
NC score	0.309144 (rank : 283)	θ value	0.813845 (rank : 408)
Query Neighborhood Hits	582	Target Neighborhood Hits	352	Shared Neighborhood Hits	231
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_HUMAN
NC score	0.308900 (rank : 284)	θ value	0.813845 (rank : 407)
Query Neighborhood Hits	582	Target Neighborhood Hits	359	Shared Neighborhood Hits	234
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

LCE1C_HUMAN
NC score	0.304293 (rank : 285)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	582	Target Neighborhood Hits	65	Shared Neighborhood Hits	52
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

KRA93_HUMAN
NC score	0.303664 (rank : 286)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	582	Target Neighborhood Hits	203	Shared Neighborhood Hits	142
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA92_HUMAN
NC score	0.302031 (rank : 287)	θ value	0.279714 (rank : 355)
Query Neighborhood Hits	582	Target Neighborhood Hits	198	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LYAM2_MOUSE
NC score	0.300173 (rank : 288)	θ value	0.0431538 (rank : 313)
Query Neighborhood Hits	582	Target Neighborhood Hits	420	Shared Neighborhood Hits	251
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

KRA98_HUMAN
NC score	0.296743 (rank : 289)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	582	Target Neighborhood Hits	185	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA15_HUMAN
NC score	0.296637 (rank : 290)	θ value	0.813845 (rank : 400)
Query Neighborhood Hits	582	Target Neighborhood Hits	126	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

LYAM3_MOUSE
NC score	0.293913 (rank : 291)	θ value	0.47712 (rank : 379)
Query Neighborhood Hits	582	Target Neighborhood Hits	390	Shared Neighborhood Hits	227
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LCE1B_HUMAN
NC score	0.293252 (rank : 292)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	582	Target Neighborhood Hits	58	Shared Neighborhood Hits	49
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

VWF_HUMAN
NC score	0.291159 (rank : 293)	θ value	0.0113563 (rank : 275)
Query Neighborhood Hits	582	Target Neighborhood Hits	396	Shared Neighborhood Hits	229
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

SORL_MOUSE
NC score	0.286123 (rank : 294)	θ value	1.81305 (rank : 453)
Query Neighborhood Hits	582	Target Neighborhood Hits	439	Shared Neighborhood Hits	229
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LYAM2_HUMAN
NC score	0.285448 (rank : 295)	θ value	5.27518 (rank : 522)
Query Neighborhood Hits	582	Target Neighborhood Hits	394	Shared Neighborhood Hits	232
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

KR412_HUMAN
NC score	0.285071 (rank : 296)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	582	Target Neighborhood Hits	178	Shared Neighborhood Hits	128
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

TDGF1_HUMAN
NC score	0.277946 (rank : 297)	θ value	1.38821 (rank : 439)
Query Neighborhood Hits	582	Target Neighborhood Hits	132	Shared Neighborhood Hits	126
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

FSTL1_HUMAN
NC score	0.277090 (rank : 298)	θ value	2.13673e-09 (rank : 107)
Query Neighborhood Hits	582	Target Neighborhood Hits	68	Shared Neighborhood Hits	61
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

RECK_MOUSE
NC score	0.275512 (rank : 299)	θ value	2.79066e-09 (rank : 109)
Query Neighborhood Hits	582	Target Neighborhood Hits	158	Shared Neighborhood Hits	134
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

ELTD1_HUMAN
NC score	0.274398 (rank : 300)	θ value	0.47712 (rank : 373)
Query Neighborhood Hits	582	Target Neighborhood Hits	269	Shared Neighborhood Hits	168
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

FSTL1_MOUSE
NC score	0.274385 (rank : 301)	θ value	2.13673e-09 (rank : 108)
Query Neighborhood Hits	582	Target Neighborhood Hits	74	Shared Neighborhood Hits	60
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

SORL_HUMAN
NC score	0.270881 (rank : 302)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	582	Target Neighborhood Hits	440	Shared Neighborhood Hits	226
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TDGF2_HUMAN
NC score	0.267585 (rank : 303)	θ value	1.38821 (rank : 440)
Query Neighborhood Hits	582	Target Neighborhood Hits	131	Shared Neighborhood Hits	122
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

PGCB_MOUSE
NC score	0.267151 (rank : 304)	θ value	0.00134147 (rank : 236)
Query Neighborhood Hits	582	Target Neighborhood Hits	459	Shared Neighborhood Hits	195
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

LYAM3_HUMAN
NC score	0.266352 (rank : 305)	θ value	0.62314 (rank : 394)
Query Neighborhood Hits	582	Target Neighborhood Hits	378	Shared Neighborhood Hits	214
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MFGM_HUMAN
NC score	0.265704 (rank : 306)	θ value	0.813845 (rank : 402)
Query Neighborhood Hits	582	Target Neighborhood Hits	150	Shared Neighborhood Hits	125
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

VWF_MOUSE
NC score	0.263021 (rank : 307)	θ value	3.19293e-05 (rank : 172)
Query Neighborhood Hits	582	Target Neighborhood Hits	381	Shared Neighborhood Hits	203
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ESM1_HUMAN
NC score	0.262043 (rank : 308)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	582	Target Neighborhood Hits	110	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

NRX3B_HUMAN
NC score	0.257826 (rank : 309)	θ value	0.0193708 (rank : 288)
Query Neighborhood Hits	582	Target Neighborhood Hits	36	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HDB5	Gene names	NRXN3, KIAA0743
Domain Architecture	No domain graphic available
Description	Neurexin-3-beta precursor (Neurexin III-beta).

KRA99_HUMAN
NC score	0.255932 (rank : 310)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	582	Target Neighborhood Hits	173	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

NRX1B_HUMAN
NC score	0.254313 (rank : 311)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	582	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

KR410_HUMAN
NC score	0.253562 (rank : 312)	θ value	5.27518 (rank : 516)
Query Neighborhood Hits	582	Target Neighborhood Hits	156	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

LCE1E_HUMAN
NC score	0.250885 (rank : 313)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	582	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

PGCB_HUMAN
NC score	0.248259 (rank : 314)	θ value	0.00102713 (rank : 229)
Query Neighborhood Hits	582	Target Neighborhood Hits	478	Shared Neighborhood Hits	192
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

SHBG_HUMAN
NC score	0.248176 (rank : 315)	θ value	0.00134147 (rank : 237)
Query Neighborhood Hits	582	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

LYAM1_HUMAN
NC score	0.245932 (rank : 316)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	582	Target Neighborhood Hits	315	Shared Neighborhood Hits	190
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LCE1D_HUMAN
NC score	0.243682 (rank : 317)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	582	Target Neighborhood Hits	44	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LYAM1_MOUSE
NC score	0.239603 (rank : 318)	θ value	8.99809 (rank : 574)
Query Neighborhood Hits	582	Target Neighborhood Hits	332	Shared Neighborhood Hits	188
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

HGFA_HUMAN
NC score	0.238625 (rank : 319)	θ value	0.00665767 (rank : 262)
Query Neighborhood Hits	582	Target Neighborhood Hits	436	Shared Neighborhood Hits	223
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LCE1F_HUMAN
NC score	0.238426 (rank : 320)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	582	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE1A_HUMAN
NC score	0.237800 (rank : 321)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	582	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

MUC13_MOUSE
NC score	0.237119 (rank : 322)	θ value	5.27518 (rank : 526)
Query Neighborhood Hits	582	Target Neighborhood Hits	447	Shared Neighborhood Hits	178
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

FA10_MOUSE
NC score	0.233874 (rank : 323)	θ value	0.0252991 (rank : 293)
Query Neighborhood Hits	582	Target Neighborhood Hits	435	Shared Neighborhood Hits	231
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

SHBG_MOUSE
NC score	0.232664 (rank : 324)	θ value	0.0193708 (rank : 290)
Query Neighborhood Hits	582	Target Neighborhood Hits	50	Shared Neighborhood Hits	42
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

HGFA_MOUSE
NC score	0.231951 (rank : 325)	θ value	0.00020696 (rank : 192)
Query Neighborhood Hits	582	Target Neighborhood Hits	419	Shared Neighborhood Hits	222
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ESM1_MOUSE
NC score	0.231000 (rank : 326)	θ value	1.81305 (rank : 445)
Query Neighborhood Hits	582	Target Neighborhood Hits	107	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA9_HUMAN
NC score	0.227346 (rank : 327)	θ value	0.00298849 (rank : 249)
Query Neighborhood Hits	582	Target Neighborhood Hits	421	Shared Neighborhood Hits	225
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FA10_HUMAN
NC score	0.226634 (rank : 328)	θ value	1.06291 (rank : 419)
Query Neighborhood Hits	582	Target Neighborhood Hits	431	Shared Neighborhood Hits	228
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

PCSK5_HUMAN
NC score	0.225443 (rank : 329)	θ value	0.0563607 (rank : 318)
Query Neighborhood Hits	582	Target Neighborhood Hits	291	Shared Neighborhood Hits	168
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

MT3_MOUSE
NC score	0.225419 (rank : 330)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	582	Target Neighborhood Hits	68	Shared Neighborhood Hits	50
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

LCE2A_HUMAN
NC score	0.223828 (rank : 331)	θ value	0.125558 (rank : 335)
Query Neighborhood Hits	582	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

KRA42_HUMAN
NC score	0.222562 (rank : 332)	θ value	1.81305 (rank : 451)
Query Neighborhood Hits	582	Target Neighborhood Hits	149	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

MMRN1_HUMAN
NC score	0.221422 (rank : 333)	θ value	0.00298849 (rank : 252)
Query Neighborhood Hits	582	Target Neighborhood Hits	636	Shared Neighborhood Hits	153
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MUC2_HUMAN
NC score	0.220525 (rank : 334)	θ value	0.125558 (rank : 336)
Query Neighborhood Hits	582	Target Neighborhood Hits	906	Shared Neighborhood Hits	226
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

FA12_HUMAN
NC score	0.217979 (rank : 335)	θ value	9.29e-05 (rank : 180)
Query Neighborhood Hits	582	Target Neighborhood Hits	425	Shared Neighborhood Hits	220
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
NC score	0.216525 (rank : 336)	θ value	0.0736092 (rank : 321)
Query Neighborhood Hits	582	Target Neighborhood Hits	404	Shared Neighborhood Hits	213
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

ISK5_HUMAN
NC score	0.216150 (rank : 337)	θ value	4.16044e-13 (rank : 75)
Query Neighborhood Hits	582	Target Neighborhood Hits	89	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

KRA24_HUMAN
NC score	0.214466 (rank : 338)	θ value	1.81305 (rank : 450)
Query Neighborhood Hits	582	Target Neighborhood Hits	192	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

PROC_MOUSE
NC score	0.213952 (rank : 339)	θ value	0.279714 (rank : 356)
Query Neighborhood Hits	582	Target Neighborhood Hits	426	Shared Neighborhood Hits	230
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

MT3_HUMAN
NC score	0.213117 (rank : 340)	θ value	5.27518 (rank : 525)
Query Neighborhood Hits	582	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

PGH2_MOUSE
NC score	0.211264 (rank : 341)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	582	Target Neighborhood Hits	113	Shared Neighborhood Hits	100
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

TIE1_HUMAN
NC score	0.211260 (rank : 342)	θ value	5.81887e-07 (rank : 133)
Query Neighborhood Hits	582	Target Neighborhood Hits	1241	Shared Neighborhood Hits	285
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CSPG4_HUMAN
NC score	0.210815 (rank : 343)	θ value	2.21117e-06 (rank : 138)
Query Neighborhood Hits	582	Target Neighborhood Hits	112	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

BMPER_MOUSE
NC score	0.210083 (rank : 344)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	582	Target Neighborhood Hits	194	Shared Neighborhood Hits	139
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CSPG4_MOUSE
NC score	0.209629 (rank : 345)	θ value	0.00134147 (rank : 233)
Query Neighborhood Hits	582	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

TIE1_MOUSE
NC score	0.208671 (rank : 346)	θ value	1.29631e-06 (rank : 136)
Query Neighborhood Hits	582	Target Neighborhood Hits	1266	Shared Neighborhood Hits	289
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

IPK1_HUMAN
NC score	0.208571 (rank : 347)	θ value	7.1131e-05 (rank : 179)
Query Neighborhood Hits	582	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

EMR3_HUMAN
NC score	0.201036 (rank : 348)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	582	Target Neighborhood Hits	245	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

PCSK6_HUMAN
NC score	0.199777 (rank : 349)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	582	Target Neighborhood Hits	298	Shared Neighborhood Hits	152
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

SPRC_HUMAN
NC score	0.199180 (rank : 350)	θ value	0.000270298 (rank : 199)
Query Neighborhood Hits	582	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
NC score	0.198614 (rank : 351)	θ value	0.000602161 (rank : 213)
Query Neighborhood Hits	582	Target Neighborhood Hits	46	Shared Neighborhood Hits	44
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

TNR16_HUMAN
NC score	0.196959 (rank : 352)	θ value	3.0926 (rank : 489)
Query Neighborhood Hits	582	Target Neighborhood Hits	183	Shared Neighborhood Hits	97
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

LCE3A_HUMAN
NC score	0.195704 (rank : 353)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	582	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

RELN_MOUSE
NC score	0.195581 (rank : 354)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	582	Target Neighborhood Hits	235	Shared Neighborhood Hits	178
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

FA7_MOUSE
NC score	0.194454 (rank : 355)	θ value	0.0431538 (rank : 309)
Query Neighborhood Hits	582	Target Neighborhood Hits	374	Shared Neighborhood Hits	192
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

BMPER_HUMAN
NC score	0.193924 (rank : 356)	θ value	3.0926 (rank : 473)
Query Neighborhood Hits	582	Target Neighborhood Hits	175	Shared Neighborhood Hits	116
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

NRG2_MOUSE
NC score	0.193100 (rank : 357)	θ value	3.0926 (rank : 483)
Query Neighborhood Hits	582	Target Neighborhood Hits	392	Shared Neighborhood Hits	123
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

PGH2_HUMAN
NC score	0.189729 (rank : 358)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	582	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

TECTA_MOUSE
NC score	0.188944 (rank : 359)	θ value	0.00869519 (rank : 270)
Query Neighborhood Hits	582	Target Neighborhood Hits	244	Shared Neighborhood Hits	174
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TNR4_MOUSE
NC score	0.188899 (rank : 360)	θ value	0.0736092 (rank : 324)
Query Neighborhood Hits	582	Target Neighborhood Hits	137	Shared Neighborhood Hits	74
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

PROC_HUMAN
NC score	0.188411 (rank : 361)	θ value	2.36792 (rank : 465)
Query Neighborhood Hits	582	Target Neighborhood Hits	406	Shared Neighborhood Hits	217
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

RELN_HUMAN
NC score	0.187597 (rank : 362)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	582	Target Neighborhood Hits	233	Shared Neighborhood Hits	172
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

PGCA_HUMAN
NC score	0.187157 (rank : 363)	θ value	0.0961366 (rank : 328)
Query Neighborhood Hits	582	Target Neighborhood Hits	821	Shared Neighborhood Hits	204
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

MCSP_MOUSE
NC score	0.186525 (rank : 364)	θ value	0.0736092 (rank : 323)
Query Neighborhood Hits	582	Target Neighborhood Hits	108	Shared Neighborhood Hits	60
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

LCE2B_HUMAN
NC score	0.185045 (rank : 365)	θ value	5.27518 (rank : 517)
Query Neighborhood Hits	582	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

TIE2_MOUSE
NC score	0.184808 (rank : 366)	θ value	0.00175202 (rank : 242)
Query Neighborhood Hits	582	Target Neighborhood Hits	1204	Shared Neighborhood Hits	275
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TICN3_MOUSE
NC score	0.184340 (rank : 367)	θ value	2.21117e-06 (rank : 142)
Query Neighborhood Hits	582	Target Neighborhood Hits	83	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

ISK4_HUMAN
NC score	0.183412 (rank : 368)	θ value	0.0193708 (rank : 286)
Query Neighborhood Hits	582	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

CO6_HUMAN
NC score	0.183385 (rank : 369)	θ value	5.27518 (rank : 511)
Query Neighborhood Hits	582	Target Neighborhood Hits	331	Shared Neighborhood Hits	158
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

SMOC1_MOUSE
NC score	0.183108 (rank : 370)	θ value	6.43352e-06 (rank : 149)
Query Neighborhood Hits	582	Target Neighborhood Hits	74	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

KAZD1_HUMAN
NC score	0.182941 (rank : 371)	θ value	4.45536e-07 (rank : 129)
Query Neighborhood Hits	582	Target Neighborhood Hits	248	Shared Neighborhood Hits	64
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

ISK7_HUMAN
NC score	0.182937 (rank : 372)	θ value	0.00035302 (rank : 202)
Query Neighborhood Hits	582	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

SMDF_HUMAN
NC score	0.182727 (rank : 373)	θ value	6.88961 (rank : 563)
Query Neighborhood Hits	582	Target Neighborhood Hits	117	Shared Neighborhood Hits	80
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

TICN2_MOUSE
NC score	0.182470 (rank : 374)	θ value	1.09739e-05 (rank : 160)
Query Neighborhood Hits	582	Target Neighborhood Hits	69	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

LCE2C_HUMAN
NC score	0.182428 (rank : 375)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	582	Target Neighborhood Hits	53	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

TIE2_HUMAN
NC score	0.182125 (rank : 376)	θ value	0.00102713 (rank : 230)
Query Neighborhood Hits	582	Target Neighborhood Hits	1192	Shared Neighborhood Hits	263
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

MUC13_HUMAN
NC score	0.181668 (rank : 377)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	582	Target Neighborhood Hits	164	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

LCE2D_HUMAN
NC score	0.180301 (rank : 378)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	582	Target Neighborhood Hits	50	Shared Neighborhood Hits	35
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

TICN2_HUMAN
NC score	0.180125 (rank : 379)	θ value	1.43324e-05 (rank : 165)
Query Neighborhood Hits	582	Target Neighborhood Hits	68	Shared Neighborhood Hits	48
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN3_HUMAN
NC score	0.179314 (rank : 380)	θ value	2.21117e-06 (rank : 141)
Query Neighborhood Hits	582	Target Neighborhood Hits	82	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

NRG1_HUMAN
NC score	0.178238 (rank : 381)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	582	Target Neighborhood Hits	285	Shared Neighborhood Hits	98
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

SMOC1_HUMAN
NC score	0.177418 (rank : 382)	θ value	3.19293e-05 (rank : 171)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

ADAM8_MOUSE
NC score	0.177368 (rank : 383)	θ value	0.0148317 (rank : 276)
Query Neighborhood Hits	582	Target Neighborhood Hits	326	Shared Neighborhood Hits	201
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ISK3_MOUSE
NC score	0.176982 (rank : 384)	θ value	0.00102713 (rank : 223)
Query Neighborhood Hits	582	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

TECTA_HUMAN
NC score	0.175360 (rank : 385)	θ value	0.00134147 (rank : 238)
Query Neighborhood Hits	582	Target Neighborhood Hits	239	Shared Neighborhood Hits	163
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

IBP7_MOUSE
NC score	0.175314 (rank : 386)	θ value	2.44474e-05 (rank : 168)
Query Neighborhood Hits	582	Target Neighborhood Hits	230	Shared Neighborhood Hits	61
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

ISK6_HUMAN
NC score	0.175142 (rank : 387)	θ value	0.125558 (rank : 334)
Query Neighborhood Hits	582	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

ISK6_MOUSE
NC score	0.174640 (rank : 388)	θ value	0.0961366 (rank : 326)
Query Neighborhood Hits	582	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

MT4_MOUSE
NC score	0.174600 (rank : 389)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	76
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

NRX2B_HUMAN
NC score	0.173938 (rank : 390)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	582	Target Neighborhood Hits	481	Shared Neighborhood Hits	55
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PGH1_MOUSE
NC score	0.173901 (rank : 391)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	582	Target Neighborhood Hits	100	Shared Neighborhood Hits	80
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

TNR16_MOUSE
NC score	0.173500 (rank : 392)	θ value	0.279714 (rank : 358)
Query Neighborhood Hits	582	Target Neighborhood Hits	178	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

PERT_HUMAN
NC score	0.172799 (rank : 393)	θ value	0.365318 (rank : 368)
Query Neighborhood Hits	582	Target Neighborhood Hits	221	Shared Neighborhood Hits	136
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

IBP7_HUMAN
NC score	0.172561 (rank : 394)	θ value	4.45536e-07 (rank : 128)
Query Neighborhood Hits	582	Target Neighborhood Hits	220	Shared Neighborhood Hits	48
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

UROL1_MOUSE
NC score	0.172300 (rank : 395)	θ value	5.27518 (rank : 541)
Query Neighborhood Hits	582	Target Neighborhood Hits	235	Shared Neighborhood Hits	131
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ADA15_MOUSE
NC score	0.170730 (rank : 396)	θ value	1.06291 (rank : 410)
Query Neighborhood Hits	582	Target Neighborhood Hits	324	Shared Neighborhood Hits	218
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADAM8_HUMAN
NC score	0.170678 (rank : 397)	θ value	1.38821 (rank : 431)
Query Neighborhood Hits	582	Target Neighborhood Hits	327	Shared Neighborhood Hits	215
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ISK4_MOUSE
NC score	0.170561 (rank : 398)	θ value	0.0431538 (rank : 310)
Query Neighborhood Hits	582	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

TNR25_HUMAN
NC score	0.170078 (rank : 399)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	582	Target Neighborhood Hits	172	Shared Neighborhood Hits	82
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

SPRL1_HUMAN
NC score	0.169602 (rank : 400)	θ value	1.09739e-05 (rank : 158)
Query Neighborhood Hits	582	Target Neighborhood Hits	231	Shared Neighborhood Hits	48
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

IPK2_HUMAN
NC score	0.169346 (rank : 401)	θ value	0.000786445 (rank : 217)
Query Neighborhood Hits	582	Target Neighborhood Hits	30	Shared Neighborhood Hits	29
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

CO7_HUMAN
NC score	0.169041 (rank : 402)	θ value	0.00869519 (rank : 268)
Query Neighborhood Hits	582	Target Neighborhood Hits	278	Shared Neighborhood Hits	141
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

TICN1_MOUSE
NC score	0.167606 (rank : 403)	θ value	1.09739e-05 (rank : 159)
Query Neighborhood Hits	582	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

KR122_HUMAN
NC score	0.166705 (rank : 404)	θ value	1.81305 (rank : 449)
Query Neighborhood Hits	582	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

TNR4_HUMAN
NC score	0.166154 (rank : 405)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	582	Target Neighborhood Hits	152	Shared Neighborhood Hits	76
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

KAZD1_MOUSE
NC score	0.166105 (rank : 406)	θ value	4.45536e-07 (rank : 130)
Query Neighborhood Hits	582	Target Neighborhood Hits	281	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

LRP5_MOUSE
NC score	0.165829 (rank : 407)	θ value	0.813845 (rank : 401)
Query Neighborhood Hits	582	Target Neighborhood Hits	236	Shared Neighborhood Hits	142
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

VASN_HUMAN
NC score	0.165511 (rank : 408)	θ value	0.00665767 (rank : 267)
Query Neighborhood Hits	582	Target Neighborhood Hits	449	Shared Neighborhood Hits	145
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

LRP6_HUMAN
NC score	0.165442 (rank : 409)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	582	Target Neighborhood Hits	235	Shared Neighborhood Hits	139
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

SMOC2_MOUSE
NC score	0.164703 (rank : 410)	θ value	0.00020696 (rank : 194)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

KR124_HUMAN
NC score	0.163827 (rank : 411)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	582	Target Neighborhood Hits	124	Shared Neighborhood Hits	84
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

SMOC2_HUMAN
NC score	0.163549 (rank : 412)	θ value	0.000602161 (rank : 212)
Query Neighborhood Hits	582	Target Neighborhood Hits	88	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

LCE4A_HUMAN
NC score	0.162780 (rank : 413)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	582	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

MEP1A_MOUSE
NC score	0.162779 (rank : 414)	θ value	3.0926 (rank : 480)
Query Neighborhood Hits	582	Target Neighborhood Hits	166	Shared Neighborhood Hits	124
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

LRP6_MOUSE
NC score	0.162743 (rank : 415)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	582	Target Neighborhood Hits	232	Shared Neighborhood Hits	136
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

NRG2_HUMAN
NC score	0.162082 (rank : 416)	θ value	3.0926 (rank : 482)
Query Neighborhood Hits	582	Target Neighborhood Hits	419	Shared Neighborhood Hits	112
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

FSTL4_MOUSE
NC score	0.161998 (rank : 417)	θ value	2.98157e-11 (rank : 92)
Query Neighborhood Hits	582	Target Neighborhood Hits	333	Shared Neighborhood Hits	64
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

ADA15_HUMAN
NC score	0.161235 (rank : 418)	θ value	0.125558 (rank : 330)
Query Neighborhood Hits	582	Target Neighborhood Hits	288	Shared Neighborhood Hits	198
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

NRG4_MOUSE
NC score	0.161071 (rank : 419)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	582	Target Neighborhood Hits	79	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

TICN1_HUMAN
NC score	0.160627 (rank : 420)	θ value	4.1701e-05 (rank : 176)
Query Neighborhood Hits	582	Target Neighborhood Hits	70	Shared Neighborhood Hits	45
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

NRG4_HUMAN
NC score	0.160447 (rank : 421)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	582	Target Neighborhood Hits	85	Shared Neighborhood Hits	67
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

CORIN_HUMAN
NC score	0.159265 (rank : 422)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	582	Target Neighborhood Hits	453	Shared Neighborhood Hits	206
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

ADA11_HUMAN
NC score	0.159010 (rank : 423)	θ value	1.38821 (rank : 428)
Query Neighborhood Hits	582	Target Neighborhood Hits	259	Shared Neighborhood Hits	180
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

LRP5_HUMAN
NC score	0.158735 (rank : 424)	θ value	0.62314 (rank : 393)
Query Neighborhood Hits	582	Target Neighborhood Hits	224	Shared Neighborhood Hits	134
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

FSTL4_HUMAN
NC score	0.158479 (rank : 425)	θ value	9.59137e-10 (rank : 105)
Query Neighborhood Hits	582	Target Neighborhood Hits	344	Shared Neighborhood Hits	62
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

ADA11_MOUSE
NC score	0.158360 (rank : 426)	θ value	1.38821 (rank : 429)
Query Neighborhood Hits	582	Target Neighborhood Hits	263	Shared Neighborhood Hits	180
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

MKS3_MOUSE
NC score	0.157966 (rank : 427)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	582	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

ISK7_MOUSE
NC score	0.155346 (rank : 428)	θ value	0.00175202 (rank : 240)
Query Neighborhood Hits	582	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

PERT_MOUSE
NC score	0.155097 (rank : 429)	θ value	3.0926 (rank : 484)
Query Neighborhood Hits	582	Target Neighborhood Hits	221	Shared Neighborhood Hits	131
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

CO8B_MOUSE
NC score	0.154971 (rank : 430)	θ value	0.0330416 (rank : 298)
Query Neighborhood Hits	582	Target Neighborhood Hits	224	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

SPRL1_MOUSE
NC score	0.154908 (rank : 431)	θ value	4.1701e-05 (rank : 175)
Query Neighborhood Hits	582	Target Neighborhood Hits	403	Shared Neighborhood Hits	44
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

KR413_HUMAN
NC score	0.154825 (rank : 432)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	582	Target Neighborhood Hits	112	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

VASN_MOUSE
NC score	0.153496 (rank : 433)	θ value	0.00175202 (rank : 243)
Query Neighborhood Hits	582	Target Neighborhood Hits	426	Shared Neighborhood Hits	131
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

EREG_HUMAN
NC score	0.153492 (rank : 434)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	582	Target Neighborhood Hits	73	Shared Neighborhood Hits	53
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

MEP1A_HUMAN
NC score	0.153127 (rank : 435)	θ value	2.36792 (rank : 462)
Query Neighborhood Hits	582	Target Neighborhood Hits	162	Shared Neighborhood Hits	124
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

PGH1_HUMAN
NC score	0.152847 (rank : 436)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	582	Target Neighborhood Hits	91	Shared Neighborhood Hits	71
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

EMR4_MOUSE
NC score	0.151802 (rank : 437)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	582	Target Neighborhood Hits	191	Shared Neighborhood Hits	103
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

ADA23_HUMAN
NC score	0.151306 (rank : 438)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	582	Target Neighborhood Hits	235	Shared Neighborhood Hits	172
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

UROL1_HUMAN
NC score	0.151154 (rank : 439)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	582	Target Neighborhood Hits	213	Shared Neighborhood Hits	120
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ADAM9_MOUSE
NC score	0.149335 (rank : 440)	θ value	0.0563607 (rank : 315)
Query Neighborhood Hits	582	Target Neighborhood Hits	325	Shared Neighborhood Hits	185
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADA23_MOUSE
NC score	0.146943 (rank : 441)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	582	Target Neighborhood Hits	245	Shared Neighborhood Hits	183
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

CORIN_MOUSE
NC score	0.146622 (rank : 442)	θ value	0.47712 (rank : 372)
Query Neighborhood Hits	582	Target Neighborhood Hits	451	Shared Neighborhood Hits	191
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

LCE5A_HUMAN
NC score	0.146316 (rank : 443)	θ value	4.03905 (rank : 499)
Query Neighborhood Hits	582	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

FSTL5_HUMAN
NC score	0.145853 (rank : 444)	θ value	6.87365e-08 (rank : 118)
Query Neighborhood Hits	582	Target Neighborhood Hits	347	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

MT4_HUMAN
NC score	0.145115 (rank : 445)	θ value	8.99809 (rank : 575)
Query Neighborhood Hits	582	Target Neighborhood Hits	83	Shared Neighborhood Hits	59
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT1X_HUMAN
NC score	0.145004 (rank : 446)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	582	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

ADA33_HUMAN
NC score	0.144475 (rank : 447)	θ value	0.163984 (rank : 338)
Query Neighborhood Hits	582	Target Neighborhood Hits	264	Shared Neighborhood Hits	168
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA19_MOUSE
NC score	0.144267 (rank : 448)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	582	Target Neighborhood Hits	315	Shared Neighborhood Hits	196
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

WFDC3_HUMAN
NC score	0.144058 (rank : 449)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	582	Target Neighborhood Hits	138	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

FSTL5_MOUSE
NC score	0.143955 (rank : 450)	θ value	4.45536e-07 (rank : 127)
Query Neighborhood Hits	582	Target Neighborhood Hits	355	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

TNR14_HUMAN
NC score	0.141792 (rank : 451)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	582	Target Neighborhood Hits	149	Shared Neighborhood Hits	82
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

ADA19_HUMAN
NC score	0.141305 (rank : 452)	θ value	1.06291 (rank : 412)
Query Neighborhood Hits	582	Target Neighborhood Hits	381	Shared Neighborhood Hits	181
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

TPA_MOUSE
NC score	0.140672 (rank : 453)	θ value	0.00665767 (rank : 265)
Query Neighborhood Hits	582	Target Neighborhood Hits	335	Shared Neighborhood Hits	162
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TNR23_MOUSE
NC score	0.140611 (rank : 454)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	582	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

ADAM9_HUMAN
NC score	0.140108 (rank : 455)	θ value	0.0431538 (rank : 307)
Query Neighborhood Hits	582	Target Neighborhood Hits	243	Shared Neighborhood Hits	164
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

CRAC1_MOUSE
NC score	0.140003 (rank : 456)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	582	Target Neighborhood Hits	112	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

VEGFC_HUMAN
NC score	0.139328 (rank : 457)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	582	Target Neighborhood Hits	128	Shared Neighborhood Hits	101
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

TPA_HUMAN
NC score	0.138756 (rank : 458)	θ value	0.000270298 (rank : 200)
Query Neighborhood Hits	582	Target Neighborhood Hits	324	Shared Neighborhood Hits	154
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

LRP10_HUMAN
NC score	0.138592 (rank : 459)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	582	Target Neighborhood Hits	197	Shared Neighborhood Hits	89
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

CRAC1_HUMAN
NC score	0.138162 (rank : 460)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	582	Target Neighborhood Hits	111	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CLC14_MOUSE
NC score	0.138045 (rank : 461)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

LRP10_MOUSE
NC score	0.137640 (rank : 462)	θ value	1.81305 (rank : 452)
Query Neighborhood Hits	582	Target Neighborhood Hits	169	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

IPK2_MOUSE
NC score	0.137043 (rank : 463)	θ value	0.0148317 (rank : 280)
Query Neighborhood Hits	582	Target Neighborhood Hits	26	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BMY7	Gene names	Spink2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 2 precursor.

APR3_MOUSE
NC score	0.136686 (rank : 464)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	582	Target Neighborhood Hits	61	Shared Neighborhood Hits	55
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

LRP3_HUMAN
NC score	0.135487 (rank : 465)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	582	Target Neighborhood Hits	280	Shared Neighborhood Hits	115
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

ADA10_HUMAN
NC score	0.134664 (rank : 466)	θ value	0.813845 (rank : 397)
Query Neighborhood Hits	582	Target Neighborhood Hits	189	Shared Neighborhood Hits	129
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

EPGN_MOUSE
NC score	0.133817 (rank : 467)	θ value	1.81305 (rank : 443)
Query Neighborhood Hits	582	Target Neighborhood Hits	63	Shared Neighborhood Hits	45
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

ADA18_MOUSE
NC score	0.133460 (rank : 468)	θ value	0.365318 (rank : 361)
Query Neighborhood Hits	582	Target Neighborhood Hits	227	Shared Neighborhood Hits	166
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADAM2_MOUSE
NC score	0.133439 (rank : 469)	θ value	0.62314 (rank : 384)
Query Neighborhood Hits	582	Target Neighborhood Hits	209	Shared Neighborhood Hits	144
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADA33_MOUSE
NC score	0.132796 (rank : 470)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	582	Target Neighborhood Hits	231	Shared Neighborhood Hits	161
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CD320_HUMAN
NC score	0.132265 (rank : 471)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	582	Target Neighborhood Hits	103	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

ADA10_MOUSE
NC score	0.131752 (rank : 472)	θ value	0.365318 (rank : 360)
Query Neighborhood Hits	582	Target Neighborhood Hits	194	Shared Neighborhood Hits	128
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADAM7_HUMAN
NC score	0.131525 (rank : 473)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	582	Target Neighborhood Hits	221	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

CLC14_HUMAN
NC score	0.131463 (rank : 474)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	582	Target Neighborhood Hits	143	Shared Neighborhood Hits	95
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

ADA22_MOUSE
NC score	0.129424 (rank : 475)	θ value	0.0330416 (rank : 297)
Query Neighborhood Hits	582	Target Neighborhood Hits	225	Shared Neighborhood Hits	139
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

VEGFC_MOUSE
NC score	0.129318 (rank : 476)	θ value	2.36792 (rank : 470)
Query Neighborhood Hits	582	Target Neighborhood Hits	119	Shared Neighborhood Hits	88
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CO9_MOUSE
NC score	0.128401 (rank : 477)	θ value	2.36792 (rank : 457)
Query Neighborhood Hits	582	Target Neighborhood Hits	153	Shared Neighborhood Hits	91
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

TNR22_MOUSE
NC score	0.127924 (rank : 478)	θ value	2.36792 (rank : 467)
Query Neighborhood Hits	582	Target Neighborhood Hits	97	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR7_HUMAN
NC score	0.126905 (rank : 479)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	67
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

MT1A_HUMAN
NC score	0.126714 (rank : 480)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	582	Target Neighborhood Hits	74	Shared Neighborhood Hits	51
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

HTRA1_HUMAN
NC score	0.126451 (rank : 481)	θ value	9.29e-05 (rank : 181)
Query Neighborhood Hits	582	Target Neighborhood Hits	155	Shared Neighborhood Hits	71
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

TLL1_MOUSE
NC score	0.125852 (rank : 482)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	582	Target Neighborhood Hits	237	Shared Neighborhood Hits	143
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

MKS3_HUMAN
NC score	0.124716 (rank : 483)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	582	Target Neighborhood Hits	79	Shared Neighborhood Hits	69
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

ADA12_HUMAN
NC score	0.124669 (rank : 484)	θ value	0.00175202 (rank : 239)
Query Neighborhood Hits	582	Target Neighborhood Hits	224	Shared Neighborhood Hits	144
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

BTC_MOUSE
NC score	0.123685 (rank : 485)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	582	Target Neighborhood Hits	67	Shared Neighborhood Hits	47
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

ADA28_HUMAN
NC score	0.123602 (rank : 486)	θ value	0.47712 (rank : 370)
Query Neighborhood Hits	582	Target Neighborhood Hits	244	Shared Neighborhood Hits	162
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

BMP1_MOUSE
NC score	0.123182 (rank : 487)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	582	Target Neighborhood Hits	236	Shared Neighborhood Hits	145
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

ADA28_MOUSE
NC score	0.123027 (rank : 488)	θ value	4.03905 (rank : 491)
Query Neighborhood Hits	582	Target Neighborhood Hits	241	Shared Neighborhood Hits	159
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

KR241_HUMAN
NC score	0.122439 (rank : 489)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	582	Target Neighborhood Hits	71	Shared Neighborhood Hits	51
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

ADA17_HUMAN
NC score	0.121897 (rank : 490)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	582	Target Neighborhood Hits	223	Shared Neighborhood Hits	140
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

BMP1_HUMAN
NC score	0.121791 (rank : 491)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	582	Target Neighborhood Hits	233	Shared Neighborhood Hits	144
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

ADA22_HUMAN
NC score	0.121623 (rank : 492)	θ value	0.0736092 (rank : 320)
Query Neighborhood Hits	582	Target Neighborhood Hits	211	Shared Neighborhood Hits	132
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

TLL2_HUMAN
NC score	0.121583 (rank : 493)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	582	Target Neighborhood Hits	241	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

ADA12_MOUSE
NC score	0.121032 (rank : 494)	θ value	4.92598e-06 (rank : 147)
Query Neighborhood Hits	582	Target Neighborhood Hits	474	Shared Neighborhood Hits	139
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

HTRA1_MOUSE
NC score	0.120997 (rank : 495)	θ value	0.000461057 (rank : 208)
Query Neighborhood Hits	582	Target Neighborhood Hits	140	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

TLL1_HUMAN
NC score	0.120942 (rank : 496)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	582	Target Neighborhood Hits	236	Shared Neighborhood Hits	140
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

ZNFX1_MOUSE
NC score	0.120359 (rank : 497)	θ value	0.813845 (rank : 409)
Query Neighborhood Hits	582	Target Neighborhood Hits	407	Shared Neighborhood Hits	117
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_HUMAN
NC score	0.120042 (rank : 498)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	582	Target Neighborhood Hits	308	Shared Neighborhood Hits	112
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CO9_HUMAN
NC score	0.119773 (rank : 499)	θ value	8.99809 (rank : 570)
Query Neighborhood Hits	582	Target Neighborhood Hits	147	Shared Neighborhood Hits	87
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

HTRA3_HUMAN
NC score	0.119176 (rank : 500)	θ value	0.000786445 (rank : 216)
Query Neighborhood Hits	582	Target Neighborhood Hits	152	Shared Neighborhood Hits	60
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

ADM1A_MOUSE
NC score	0.118992 (rank : 501)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	582	Target Neighborhood Hits	230	Shared Neighborhood Hits	165
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA25_MOUSE
NC score	0.118468 (rank : 502)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	582	Target Neighborhood Hits	213	Shared Neighborhood Hits	151
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

TNR9_MOUSE
NC score	0.118390 (rank : 503)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	582	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

LCE3B_HUMAN
NC score	0.118344 (rank : 504)	θ value	5.27518 (rank : 518)
Query Neighborhood Hits	582	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

MT1B_HUMAN
NC score	0.118153 (rank : 505)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	582	Target Neighborhood Hits	87	Shared Neighborhood Hits	60
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

CT127_HUMAN
NC score	0.117092 (rank : 506)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	582	Target Neighborhood Hits	67	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

ADA32_HUMAN
NC score	0.116791 (rank : 507)	θ value	0.47712 (rank : 371)
Query Neighborhood Hits	582	Target Neighborhood Hits	216	Shared Neighborhood Hits	147
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA24_MOUSE
NC score	0.115876 (rank : 508)	θ value	1.06291 (rank : 413)
Query Neighborhood Hits	582	Target Neighborhood Hits	230	Shared Neighborhood Hits	161
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

MEP1B_MOUSE
NC score	0.115549 (rank : 509)	θ value	3.0926 (rank : 481)
Query Neighborhood Hits	582	Target Neighborhood Hits	127	Shared Neighborhood Hits	84
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

KR123_HUMAN
NC score	0.115294 (rank : 510)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	582	Target Neighborhood Hits	75	Shared Neighborhood Hits	50
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

ADA21_MOUSE
NC score	0.114226 (rank : 511)	θ value	3.0926 (rank : 472)
Query Neighborhood Hits	582	Target Neighborhood Hits	172	Shared Neighborhood Hits	123
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

TLL2_MOUSE
NC score	0.114185 (rank : 512)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	582	Target Neighborhood Hits	240	Shared Neighborhood Hits	143
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

KR111_HUMAN
NC score	0.113896 (rank : 513)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	582	Target Neighborhood Hits	90	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

LORI_MOUSE
NC score	0.113804 (rank : 514)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	582	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

ADA18_HUMAN
NC score	0.113326 (rank : 515)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	582	Target Neighborhood Hits	184	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ST14_MOUSE
NC score	0.113010 (rank : 516)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	582	Target Neighborhood Hits	419	Shared Neighborhood Hits	172
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ADA17_MOUSE
NC score	0.112848 (rank : 517)	θ value	1.06291 (rank : 411)
Query Neighborhood Hits	582	Target Neighborhood Hits	201	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA30_HUMAN
NC score	0.112846 (rank : 518)	θ value	1.06291 (rank : 414)
Query Neighborhood Hits	582	Target Neighborhood Hits	391	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADAM7_MOUSE
NC score	0.112552 (rank : 519)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	582	Target Neighborhood Hits	200	Shared Neighborhood Hits	139
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADA32_MOUSE
NC score	0.112426 (rank : 520)	θ value	0.365318 (rank : 362)
Query Neighborhood Hits	582	Target Neighborhood Hits	219	Shared Neighborhood Hits	154
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

APR3_HUMAN
NC score	0.111987 (rank : 521)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	582	Target Neighborhood Hits	50	Shared Neighborhood Hits	47
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

ST14_HUMAN
NC score	0.111853 (rank : 522)	θ value	4.03905 (rank : 507)
Query Neighborhood Hits	582	Target Neighborhood Hits	409	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

MT1H_HUMAN
NC score	0.111400 (rank : 523)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	582	Target Neighborhood Hits	78	Shared Neighborhood Hits	53
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

HTRA3_MOUSE
NC score	0.109897 (rank : 524)	θ value	0.00298849 (rank : 251)
Query Neighborhood Hits	582	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

TNR9_HUMAN
NC score	0.109172 (rank : 525)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	582	Target Neighborhood Hits	166	Shared Neighborhood Hits	79
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

MT2_MOUSE
NC score	0.108702 (rank : 526)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	49
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

CYR61_MOUSE
NC score	0.107157 (rank : 527)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	582	Target Neighborhood Hits	156	Shared Neighborhood Hits	82
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

ADA21_HUMAN
NC score	0.106900 (rank : 528)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	582	Target Neighborhood Hits	181	Shared Neighborhood Hits	130
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

EREG_MOUSE
NC score	0.106790 (rank : 529)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	582	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

TNR8_HUMAN
NC score	0.106751 (rank : 530)	θ value	2.36792 (rank : 468)
Query Neighborhood Hits	582	Target Neighborhood Hits	198	Shared Neighborhood Hits	86
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

EPGN_HUMAN
NC score	0.106301 (rank : 531)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	582	Target Neighborhood Hits	59	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

CO8A_HUMAN
NC score	0.105507 (rank : 532)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	582	Target Neighborhood Hits	200	Shared Neighborhood Hits	102
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

TNR8_MOUSE
NC score	0.105156 (rank : 533)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	582	Target Neighborhood Hits	208	Shared Neighborhood Hits	80
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

CO8B_HUMAN
NC score	0.104734 (rank : 534)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	582	Target Neighborhood Hits	199	Shared Neighborhood Hits	92
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADM1B_MOUSE
NC score	0.104420 (rank : 535)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	582	Target Neighborhood Hits	236	Shared Neighborhood Hits	139
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADAM2_HUMAN
NC score	0.104391 (rank : 536)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	582	Target Neighborhood Hits	175	Shared Neighborhood Hits	124
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

CHRD_HUMAN
NC score	0.104121 (rank : 537)	θ value	3.0926 (rank : 475)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

TGFA_HUMAN
NC score	0.103355 (rank : 538)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	582	Target Neighborhood Hits	61	Shared Neighborhood Hits	44
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

BTC_HUMAN
NC score	0.102993 (rank : 539)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	582	Target Neighborhood Hits	70	Shared Neighborhood Hits	47
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CYR61_HUMAN
NC score	0.102321 (rank : 540)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	582	Target Neighborhood Hits	159	Shared Neighborhood Hits	85
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

SPR2D_MOUSE
NC score	0.100911 (rank : 541)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	582	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

MT1_MOUSE
NC score	0.100847 (rank : 542)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	582	Target Neighborhood Hits	72	Shared Neighborhood Hits	45
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MATN1_MOUSE
NC score	0.100831 (rank : 543)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	582	Target Neighborhood Hits	186	Shared Neighborhood Hits	111
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_HUMAN
NC score	0.100557 (rank : 544)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	582	Target Neighborhood Hits	191	Shared Neighborhood Hits	114
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

HTRA4_HUMAN
NC score	0.099793 (rank : 545)	θ value	0.0148317 (rank : 279)
Query Neighborhood Hits	582	Target Neighborhood Hits	119	Shared Neighborhood Hits	42
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

CHRD_MOUSE
NC score	0.099065 (rank : 546)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

LRP12_HUMAN
NC score	0.098694 (rank : 547)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	582	Target Neighborhood Hits	205	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
NC score	0.098146 (rank : 548)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	582	Target Neighborhood Hits	180	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

HBEGF_HUMAN
NC score	0.097173 (rank : 549)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	582	Target Neighborhood Hits	61	Shared Neighborhood Hits	43
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

CO8A_MOUSE
NC score	0.096976 (rank : 550)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	582	Target Neighborhood Hits	182	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

TNR5_MOUSE
NC score	0.096516 (rank : 551)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	582	Target Neighborhood Hits	131	Shared Neighborhood Hits	68
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

ADA29_HUMAN
NC score	0.096340 (rank : 552)	θ value	1.38821 (rank : 430)
Query Neighborhood Hits	582	Target Neighborhood Hits	247	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

AD26A_MOUSE
NC score	0.094748 (rank : 553)	θ value	0.0431538 (rank : 306)
Query Neighborhood Hits	582	Target Neighborhood Hits	165	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

GP128_MOUSE
NC score	0.094070 (rank : 554)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	582	Target Neighborhood Hits	141	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

TNR3_MOUSE
NC score	0.093826 (rank : 555)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	582	Target Neighborhood Hits	113	Shared Neighborhood Hits	61
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

KR131_HUMAN
NC score	0.093452 (rank : 556)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	582	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

DKK3_MOUSE
NC score	0.092768 (rank : 557)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	582	Target Neighborhood Hits	83	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

ODFP_MOUSE
NC score	0.091252 (rank : 558)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	582	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PHXR5_MOUSE
NC score	0.090611 (rank : 559)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

TNR7_MOUSE
NC score	0.090522 (rank : 560)	θ value	8.99809 (rank : 580)
Query Neighborhood Hits	582	Target Neighborhood Hits	112	Shared Neighborhood Hits	54
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

BAI1_HUMAN
NC score	0.090336 (rank : 561)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	582	Target Neighborhood Hits	375	Shared Neighborhood Hits	78
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

TGFA_MOUSE
NC score	0.089794 (rank : 562)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	582	Target Neighborhood Hits	62	Shared Neighborhood Hits	42
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

KR134_HUMAN
NC score	0.089580 (rank : 563)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	49
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

KR261_HUMAN
NC score	0.089155 (rank : 564)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	582	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

CTGF_HUMAN
NC score	0.089043 (rank : 565)	θ value	0.365318 (rank : 363)
Query Neighborhood Hits	582	Target Neighborhood Hits	128	Shared Neighborhood Hits	70
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

SPR2G_MOUSE
NC score	0.089035 (rank : 566)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	582	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

GP128_HUMAN
NC score	0.088960 (rank : 567)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	582	Target Neighborhood Hits	135	Shared Neighborhood Hits	43
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

SPR2H_MOUSE
NC score	0.088919 (rank : 568)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	582	Target Neighborhood Hits	82	Shared Neighborhood Hits	36
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

GP125_HUMAN
NC score	0.088874 (rank : 569)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	582	Target Neighborhood Hits	327	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

XLRS1_MOUSE
NC score	0.088547 (rank : 570)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	582	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

TNR19_MOUSE
NC score	0.087650 (rank : 571)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	582	Target Neighborhood Hits	100	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR11_HUMAN
NC score	0.087560 (rank : 572)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	582	Target Neighborhood Hits	135	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TMPS6_HUMAN
NC score	0.087039 (rank : 573)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	582	Target Neighborhood Hits	338	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

GP124_HUMAN
NC score	0.086676 (rank : 574)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	582	Target Neighborhood Hits	304	Shared Neighborhood Hits	24
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

XLRS1_HUMAN
NC score	0.086605 (rank : 575)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	582	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

RSPO4_HUMAN
NC score	0.086310 (rank : 576)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	582	Target Neighborhood Hits	110	Shared Neighborhood Hits	65
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

GP124_MOUSE
NC score	0.086236 (rank : 577)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	582	Target Neighborhood Hits	423	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

MT1E_HUMAN
NC score	0.085222 (rank : 578)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	582	Target Neighborhood Hits	75	Shared Neighborhood Hits	52
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

BAI1_MOUSE
NC score	0.084575 (rank : 579)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	582	Target Neighborhood Hits	340	Shared Neighborhood Hits	69
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

LRC21_HUMAN
NC score	0.084259 (rank : 580)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	582	Target Neighborhood Hits	456	Shared Neighborhood Hits	32
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

C1RA_MOUSE
NC score	0.084006 (rank : 581)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	582	Target Neighborhood Hits	379	Shared Neighborhood Hits	137
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

KR133_HUMAN
NC score	0.083858 (rank : 582)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	582	Target Neighborhood Hits	66	Shared Neighborhood Hits	49
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

GP125_MOUSE
NC score	0.083602 (rank : 583)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	582	Target Neighborhood Hits	329	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

TMPS6_MOUSE
NC score	0.082832 (rank : 584)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	582	Target Neighborhood Hits	341	Shared Neighborhood Hits	123
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

C1RB_MOUSE
NC score	0.082578 (rank : 585)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	582	Target Neighborhood Hits	380	Shared Neighborhood Hits	136
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

RSPO3_HUMAN
NC score	0.082443 (rank : 586)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	582	Target Neighborhood Hits	128	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

ASTN_MOUSE
NC score	0.082350 (rank : 587)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	582	Target Neighborhood Hits	98	Shared Neighborhood Hits	68
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

TNR6_MOUSE
NC score	0.082253 (rank : 588)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	582	Target Neighborhood Hits	99	Shared Neighborhood Hits	54
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

GP144_HUMAN
NC score	0.082049 (rank : 589)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	582	Target Neighborhood Hits	108	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

ADA20_HUMAN
NC score	0.081899 (rank : 590)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	582	Target Neighborhood Hits	143	Shared Neighborhood Hits	90
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ASTN_HUMAN
NC score	0.081780 (rank : 591)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	582	Target Neighborhood Hits	105	Shared Neighborhood Hits	71
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

BAI3_MOUSE
NC score	0.081545 (rank : 592)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	582	Target Neighborhood Hits	250	Shared Neighborhood Hits	61
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

TNR26_MOUSE
NC score	0.081052 (rank : 593)	θ value	5.27518 (rank : 539)
Query Neighborhood Hits	582	Target Neighborhood Hits	106	Shared Neighborhood Hits	58
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

FINC_MOUSE
NC score	0.080632 (rank : 594)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	582	Target Neighborhood Hits	309	Shared Neighborhood Hits	69
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

LRC21_MOUSE
NC score	0.080384 (rank : 595)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	582	Target Neighborhood Hits	462	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

FINC_HUMAN
NC score	0.080242 (rank : 596)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	582	Target Neighborhood Hits	302	Shared Neighborhood Hits	62
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

BAI3_HUMAN
NC score	0.079715 (rank : 597)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	582	Target Neighborhood Hits	246	Shared Neighborhood Hits	57
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CTGF_MOUSE
NC score	0.079690 (rank : 598)	θ value	2.36792 (rank : 458)
Query Neighborhood Hits	582	Target Neighborhood Hits	124	Shared Neighborhood Hits	71
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

DKK3_HUMAN
NC score	0.078905 (rank : 599)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	582	Target Neighborhood Hits	74	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

GLPC_HUMAN
NC score	0.078832 (rank : 600)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	582	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P04921, Q92642	Gene names	GYPC, GPC
Domain Architecture
Description	Glycophorin C (PAS-2') (Glycoprotein beta) (GLPC) (Glycoconnectin) (Sialoglycoprotein D) (Glycophorin D) (GPD) (CD236 antigen).

SPR2B_MOUSE
NC score	0.078490 (rank : 601)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	582	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

UROK_HUMAN
NC score	0.078404 (rank : 602)	θ value	1.38821 (rank : 441)
Query Neighborhood Hits	582	Target Neighborhood Hits	272	Shared Neighborhood Hits	109
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

GP116_HUMAN
NC score	0.078158 (rank : 603)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	582	Target Neighborhood Hits	167	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

RSPO4_MOUSE
NC score	0.077875 (rank : 604)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	582	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SPR2F_HUMAN
NC score	0.077836 (rank : 605)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	582	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

GP133_HUMAN
NC score	0.077657 (rank : 606)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	582	Target Neighborhood Hits	115	Shared Neighborhood Hits	15
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

MT1L_HUMAN
NC score	0.077620 (rank : 607)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	582	Target Neighborhood Hits	73	Shared Neighborhood Hits	48
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

CFAI_MOUSE
NC score	0.077591 (rank : 608)	θ value	0.125558 (rank : 332)
Query Neighborhood Hits	582	Target Neighborhood Hits	290	Shared Neighborhood Hits	88
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

TNR19_HUMAN
NC score	0.077186 (rank : 609)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	582	Target Neighborhood Hits	89	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

GP112_HUMAN
NC score	0.076999 (rank : 610)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	582	Target Neighborhood Hits	441	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

NRG3_MOUSE
NC score	0.076535 (rank : 611)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	582	Target Neighborhood Hits	132	Shared Neighborhood Hits	73
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

UROK_MOUSE
NC score	0.076156 (rank : 612)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	582	Target Neighborhood Hits	273	Shared Neighborhood Hits	112
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

CAD23_MOUSE
NC score	0.076024 (rank : 613)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	582	Target Neighborhood Hits	208	Shared Neighborhood Hits	17
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

PAPPA_HUMAN
NC score	0.075859 (rank : 614)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	582	Target Neighborhood Hits	161	Shared Neighborhood Hits	73
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

CAD23_HUMAN
NC score	0.075750 (rank : 615)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	582	Target Neighborhood Hits	197	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

KR132_HUMAN
NC score	0.075255 (rank : 616)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	582	Target Neighborhood Hits	69	Shared Neighborhood Hits	46
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

BAI2_MOUSE
NC score	0.075118 (rank : 617)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	582	Target Neighborhood Hits	323	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

PAPPA_MOUSE
NC score	0.074920 (rank : 618)	θ value	5.27518 (rank : 530)
Query Neighborhood Hits	582	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

NOV_HUMAN
NC score	0.074033 (rank : 619)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	582	Target Neighborhood Hits	128	Shared Neighborhood Hits	74
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

TNR3_HUMAN
NC score	0.074021 (rank : 620)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	582	Target Neighborhood Hits	145	Shared Neighborhood Hits	55
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

BAI2_HUMAN
NC score	0.073743 (rank : 621)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	582	Target Neighborhood Hits	332	Shared Neighborhood Hits	55
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TNR6B_HUMAN
NC score	0.073699 (rank : 622)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	582	Target Neighborhood Hits	103	Shared Neighborhood Hits	47
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

FA5_HUMAN
NC score	0.073645 (rank : 623)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	582	Target Neighborhood Hits	172	Shared Neighborhood Hits	24
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

HBEGF_MOUSE
NC score	0.073352 (rank : 624)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	582	Target Neighborhood Hits	48	Shared Neighborhood Hits	32
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

GP113_HUMAN
NC score	0.073287 (rank : 625)	θ value	5.27518 (rank : 515)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

PCD16_HUMAN
NC score	0.073104 (rank : 626)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	582	Target Neighborhood Hits	245	Shared Neighborhood Hits	20
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PCD15_HUMAN
NC score	0.072857 (rank : 627)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	582	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

NRG3_HUMAN
NC score	0.072813 (rank : 628)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	582	Target Neighborhood Hits	119	Shared Neighborhood Hits	63
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

GP123_HUMAN
NC score	0.072268 (rank : 629)	θ value	1.81305 (rank : 448)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

PCD15_MOUSE
NC score	0.072243 (rank : 630)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	582	Target Neighborhood Hits	262	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

RSPO3_MOUSE
NC score	0.071937 (rank : 631)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	62
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

MT1G_HUMAN
NC score	0.071700 (rank : 632)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	582	Target Neighborhood Hits	63	Shared Neighborhood Hits	34
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

LRC24_HUMAN
NC score	0.071490 (rank : 633)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	582	Target Neighborhood Hits	404	Shared Neighborhood Hits	27
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LPHN2_HUMAN
NC score	0.071006 (rank : 634)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	582	Target Neighborhood Hits	136	Shared Neighborhood Hits	17
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

CS1A_MOUSE
NC score	0.070980 (rank : 635)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	582	Target Neighborhood Hits	360	Shared Neighborhood Hits	120
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CRDL2_MOUSE
NC score	0.070937 (rank : 636)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

C1R_HUMAN
NC score	0.070891 (rank : 637)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	582	Target Neighborhood Hits	364	Shared Neighborhood Hits	125
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

LPHN1_HUMAN
NC score	0.070871 (rank : 638)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	582	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

CS1B_MOUSE
NC score	0.070794 (rank : 639)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	582	Target Neighborhood Hits	361	Shared Neighborhood Hits	120
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

GPR98_HUMAN
NC score	0.070553 (rank : 640)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	582	Target Neighborhood Hits	202	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

DCBD1_HUMAN
NC score	0.070378 (rank : 641)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	582	Target Neighborhood Hits	110	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

SPR2I_MOUSE
NC score	0.070058 (rank : 642)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	582	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

GPR64_HUMAN
NC score	0.069814 (rank : 643)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	582	Target Neighborhood Hits	207	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

LPHN3_HUMAN
NC score	0.069640 (rank : 644)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	582	Target Neighborhood Hits	139	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

WISP2_HUMAN
NC score	0.069526 (rank : 645)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	582	Target Neighborhood Hits	126	Shared Neighborhood Hits	61
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

TNR5_HUMAN
NC score	0.069481 (rank : 646)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	53
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

GPR64_MOUSE
NC score	0.069371 (rank : 647)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	582	Target Neighborhood Hits	156	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

MASP2_MOUSE
NC score	0.069292 (rank : 648)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	582	Target Neighborhood Hits	382	Shared Neighborhood Hits	128
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

IDD_HUMAN
NC score	0.069225 (rank : 649)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	582	Target Neighborhood Hits	127	Shared Neighborhood Hits	45
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

DCBD2_MOUSE
NC score	0.069045 (rank : 650)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	582	Target Neighborhood Hits	113	Shared Neighborhood Hits	23
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

NEU1_MOUSE
NC score	0.068845 (rank : 651)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	582	Target Neighborhood Hits	64	Shared Neighborhood Hits	54
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

MASP2_HUMAN
NC score	0.068656 (rank : 652)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	582	Target Neighborhood Hits	364	Shared Neighborhood Hits	121
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

LRC24_MOUSE
NC score	0.068201 (rank : 653)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	582	Target Neighborhood Hits	387	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

DCBD2_HUMAN
NC score	0.068180 (rank : 654)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	582	Target Neighborhood Hits	118	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

TNR11_MOUSE
NC score	0.067842 (rank : 655)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	582	Target Neighborhood Hits	121	Shared Neighborhood Hits	59
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

WISP1_MOUSE
NC score	0.067783 (rank : 656)	θ value	1.81305 (rank : 455)
Query Neighborhood Hits	582	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

CFAI_HUMAN
NC score	0.067732 (rank : 657)	θ value	0.0961366 (rank : 325)
Query Neighborhood Hits	582	Target Neighborhood Hits	289	Shared Neighborhood Hits	77
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

C1S_HUMAN
NC score	0.067408 (rank : 658)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	582	Target Neighborhood Hits	359	Shared Neighborhood Hits	126
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CRDL2_HUMAN
NC score	0.067295 (rank : 659)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	582	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

PCDLK_HUMAN
NC score	0.067024 (rank : 660)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	582	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

WISP2_MOUSE
NC score	0.066982 (rank : 661)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	582	Target Neighborhood Hits	129	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

MT1F_HUMAN
NC score	0.066955 (rank : 662)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	582	Target Neighborhood Hits	73	Shared Neighborhood Hits	47
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

GNPTA_HUMAN
NC score	0.066860 (rank : 663)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	582	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

THYG_HUMAN
NC score	0.066569 (rank : 664)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	582	Target Neighborhood Hits	154	Shared Neighborhood Hits	67
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

LCE3C_HUMAN
NC score	0.066509 (rank : 665)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	582	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

GNPTA_MOUSE
NC score	0.066357 (rank : 666)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	582	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

RSPO2_HUMAN
NC score	0.066341 (rank : 667)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	582	Target Neighborhood Hits	90	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
NC score	0.066177 (rank : 668)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	582	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

NRP2_HUMAN
NC score	0.065731 (rank : 669)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	26
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

IDD_MOUSE
NC score	0.065696 (rank : 670)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	582	Target Neighborhood Hits	151	Shared Neighborhood Hits	45
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

MCSP_HUMAN
NC score	0.065646 (rank : 671)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	582	Target Neighborhood Hits	48	Shared Neighborhood Hits	31
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

LRIG1_MOUSE
NC score	0.065480 (rank : 672)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	582	Target Neighborhood Hits	627	Shared Neighborhood Hits	30
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

NOV_MOUSE
NC score	0.065471 (rank : 673)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	582	Target Neighborhood Hits	130	Shared Neighborhood Hits	70
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

LRIG1_HUMAN
NC score	0.065152 (rank : 674)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	582	Target Neighborhood Hits	654	Shared Neighborhood Hits	27
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

GP114_HUMAN
NC score	0.065100 (rank : 675)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	582	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

HG2A_MOUSE
NC score	0.064491 (rank : 676)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	582	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

FA8_HUMAN
NC score	0.064335 (rank : 677)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	582	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
NC score	0.064007 (rank : 678)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	582	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

MUCDL_HUMAN
NC score	0.063922 (rank : 679)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	582	Target Neighborhood Hits	777	Shared Neighborhood Hits	59
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MASP1_HUMAN
NC score	0.063645 (rank : 680)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	582	Target Neighborhood Hits	369	Shared Neighborhood Hits	121
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

TNR1B_HUMAN
NC score	0.063270 (rank : 681)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	582	Target Neighborhood Hits	127	Shared Neighborhood Hits	55
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

GPR98_MOUSE
NC score	0.063100 (rank : 682)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	582	Target Neighborhood Hits	206	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

NRP2_MOUSE
NC score	0.063051 (rank : 683)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	582	Target Neighborhood Hits	113	Shared Neighborhood Hits	23
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

WISP1_HUMAN
NC score	0.062906 (rank : 684)	θ value	5.27518 (rank : 542)
Query Neighborhood Hits	582	Target Neighborhood Hits	121	Shared Neighborhood Hits	58
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

SPR2E_MOUSE
NC score	0.062866 (rank : 685)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	582	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

HPLN2_MOUSE
NC score	0.062832 (rank : 686)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	582	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

GPR56_HUMAN
NC score	0.062509 (rank : 687)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	582	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

MASP1_MOUSE
NC score	0.062496 (rank : 688)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	582	Target Neighborhood Hits	364	Shared Neighborhood Hits	121
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

NRP1_MOUSE
NC score	0.061935 (rank : 689)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	24
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

GPIX_HUMAN
NC score	0.061799 (rank : 690)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	582	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	P14770, Q14445, Q92525	Gene names	GP9
Domain Architecture
Description	Platelet glycoprotein IX precursor (GPIX) (CD42a antigen).

NRP1_HUMAN
NC score	0.061620 (rank : 691)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	582	Target Neighborhood Hits	119	Shared Neighborhood Hits	25
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

SDK1_MOUSE
NC score	0.061596 (rank : 692)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	582	Target Neighborhood Hits	495	Shared Neighborhood Hits	51
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

DSCL1_HUMAN
NC score	0.061413 (rank : 693)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	582	Target Neighborhood Hits	589	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

HPLN2_HUMAN
NC score	0.061394 (rank : 694)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	582	Target Neighborhood Hits	80	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

MUCDL_MOUSE
NC score	0.061208 (rank : 695)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	582	Target Neighborhood Hits	461	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SDK2_MOUSE
NC score	0.061169 (rank : 696)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	582	Target Neighborhood Hits	480	Shared Neighborhood Hits	47
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_HUMAN
NC score	0.060956 (rank : 697)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	582	Target Neighborhood Hits	511	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

LRIG3_MOUSE
NC score	0.060918 (rank : 698)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	582	Target Neighborhood Hits	611	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

ECM2_HUMAN
NC score	0.060880 (rank : 699)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	582	Target Neighborhood Hits	402	Shared Neighborhood Hits	46
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

CJ095_HUMAN
NC score	0.060821 (rank : 700)	θ value	4.03905 (rank : 494)
Query Neighborhood Hits	582	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

MEP1B_HUMAN
NC score	0.060706 (rank : 701)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	582	Target Neighborhood Hits	98	Shared Neighborhood Hits	55
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

LRIG2_MOUSE
NC score	0.060694 (rank : 702)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	582	Target Neighborhood Hits	586	Shared Neighborhood Hits	28
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

HG2A_HUMAN
NC score	0.060487 (rank : 703)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	582	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

CAD17_MOUSE
NC score	0.060367 (rank : 704)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	582	Target Neighborhood Hits	157	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

GPR56_MOUSE
NC score	0.060321 (rank : 705)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	582	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

MT2_HUMAN
NC score	0.060308 (rank : 706)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	582	Target Neighborhood Hits	69	Shared Neighborhood Hits	46
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

SDK2_HUMAN
NC score	0.060208 (rank : 707)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	582	Target Neighborhood Hits	495	Shared Neighborhood Hits	47
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

NEO1_MOUSE
NC score	0.060195 (rank : 708)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	582	Target Neighborhood Hits	523	Shared Neighborhood Hits	47
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

DSCAM_HUMAN
NC score	0.060191 (rank : 709)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	582	Target Neighborhood Hits	524	Shared Neighborhood Hits	42
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

SO3A1_MOUSE
NC score	0.059954 (rank : 710)	θ value	0.21417 (rank : 349)
Query Neighborhood Hits	582	Target Neighborhood Hits	59	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

LRIG3_HUMAN
NC score	0.059917 (rank : 711)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	582	Target Neighborhood Hits	601	Shared Neighborhood Hits	30
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LRC17_MOUSE
NC score	0.059795 (rank : 712)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	582	Target Neighborhood Hits	268	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CXD9	Gene names	Lrrc17
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor.

GP126_HUMAN
NC score	0.059788 (rank : 713)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	582	Target Neighborhood Hits	187	Shared Neighborhood Hits	23
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

NEO1_HUMAN
NC score	0.059750 (rank : 714)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	582	Target Neighborhood Hits	530	Shared Neighborhood Hits	49
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

TMPS7_MOUSE
NC score	0.059506 (rank : 715)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	582	Target Neighborhood Hits	275	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

SO3A1_HUMAN
NC score	0.059489 (rank : 716)	θ value	0.21417 (rank : 348)
Query Neighborhood Hits	582	Target Neighborhood Hits	54	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

THYG_MOUSE
NC score	0.059318 (rank : 717)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	582	Target Neighborhood Hits	161	Shared Neighborhood Hits	69
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

LRIG2_HUMAN
NC score	0.059283 (rank : 718)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	582	Target Neighborhood Hits	595	Shared Neighborhood Hits	28
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

TMPS7_HUMAN
NC score	0.059231 (rank : 719)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	582	Target Neighborhood Hits	275	Shared Neighborhood Hits	68
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

GPR97_MOUSE
NC score	0.059178 (rank : 720)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	582	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

SO4A1_HUMAN
NC score	0.059117 (rank : 721)	θ value	0.0193708 (rank : 291)
Query Neighborhood Hits	582	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

SO2A1_MOUSE
NC score	0.059117 (rank : 722)	θ value	0.0148317 (rank : 283)
Query Neighborhood Hits	582	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

LRC17_HUMAN
NC score	0.059063 (rank : 723)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	582	Target Neighborhood Hits	267	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N6Y2, Q13288, Q6UWA7, Q75MG5	Gene names	LRRC17, P37NB
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor (p37NB).

CAD17_HUMAN
NC score	0.058547 (rank : 724)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	582	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	Q12864, Q15336	Gene names	CDH17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (Intestinal peptide-associated transporter HPT-1).

CRDL1_MOUSE
NC score	0.058435 (rank : 725)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

PUNC_HUMAN
NC score	0.058423 (rank : 726)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	582	Target Neighborhood Hits	449	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

TNR6_HUMAN
NC score	0.058392 (rank : 727)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	582	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

PUNC_MOUSE
NC score	0.058281 (rank : 728)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	582	Target Neighborhood Hits	501	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

PCDH1_HUMAN
NC score	0.058233 (rank : 729)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	582	Target Neighborhood Hits	174	Shared Neighborhood Hits	12
SwissProt Accessions	Q08174	Gene names	PCDH1
Domain Architecture
Description	Protocadherin-1 precursor (Protocadherin-42) (PC42) (Cadherin-like protein 1).

GP115_MOUSE
NC score	0.058091 (rank : 730)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	582	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

TR19L_HUMAN
NC score	0.057618 (rank : 731)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	582	Target Neighborhood Hits	99	Shared Neighborhood Hits	34
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

HPLN4_MOUSE
NC score	0.057402 (rank : 732)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	582	Target Neighborhood Hits	98	Shared Neighborhood Hits	14
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

PCDH7_HUMAN
NC score	0.057294 (rank : 733)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	582	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

PCDH9_HUMAN
NC score	0.056865 (rank : 734)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	582	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

DCC_MOUSE
NC score	0.056853 (rank : 735)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	582	Target Neighborhood Hits	896	Shared Neighborhood Hits	68
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

CAD16_HUMAN
NC score	0.056690 (rank : 736)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	582	Target Neighborhood Hits	159	Shared Neighborhood Hits	10
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

GP1BB_HUMAN
NC score	0.056644 (rank : 737)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	582	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	P13224, Q8NG40	Gene names	GP1BB
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (Antigen CD42b-beta) (CD42c antigen).

PCD20_MOUSE
NC score	0.056607 (rank : 738)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	582	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BIZ0, Q8BIV2	Gene names	Pcdh20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor.

PCD20_HUMAN
NC score	0.056592 (rank : 739)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	582	Target Neighborhood Hits	153	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N6Y1, Q8NDN4, Q9NRT9	Gene names	PCDH20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor (Protocadherin-13).

AREG_HUMAN
NC score	0.056454 (rank : 740)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	582	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	P15514	Gene names	AREG
Domain Architecture	No domain graphic available
Description	Amphiregulin precursor (AR) (Colorectum cell-derived growth factor) (CRDGF).

IBP3_HUMAN
NC score	0.056412 (rank : 741)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	582	Target Neighborhood Hits	67	Shared Neighborhood Hits	31
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

LRFN2_HUMAN
NC score	0.056347 (rank : 742)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	582	Target Neighborhood Hits	450	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN4_HUMAN
NC score	0.056320 (rank : 743)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	582	Target Neighborhood Hits	462	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

CRDL1_HUMAN
NC score	0.056301 (rank : 744)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	582	Target Neighborhood Hits	75	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

SO2A1_HUMAN
NC score	0.056290 (rank : 745)	θ value	1.06291 (rank : 425)
Query Neighborhood Hits	582	Target Neighborhood Hits	40	Shared Neighborhood Hits	34
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

HPLN3_MOUSE
NC score	0.056282 (rank : 746)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	582	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

SO5A1_HUMAN
NC score	0.056213 (rank : 747)	θ value	1.06291 (rank : 426)
Query Neighborhood Hits	582	Target Neighborhood Hits	57	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

MT1I_HUMAN
NC score	0.056148 (rank : 748)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	582	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

CAD16_MOUSE
NC score	0.056147 (rank : 749)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	582	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	O88338, Q9JLZ5	Gene names	Cdh16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

HPLN4_HUMAN
NC score	0.056051 (rank : 750)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	582	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

DCC_HUMAN
NC score	0.055976 (rank : 751)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	582	Target Neighborhood Hits	583	Shared Neighborhood Hits	53
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

GP115_HUMAN
NC score	0.055691 (rank : 752)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	582	Target Neighborhood Hits	87	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

SPR2F_MOUSE
NC score	0.055600 (rank : 753)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	582	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

TNR1A_MOUSE
NC score	0.055500 (rank : 754)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	582	Target Neighborhood Hits	131	Shared Neighborhood Hits	49
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

PC11X_HUMAN
NC score	0.055439 (rank : 755)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	582	Target Neighborhood Hits	199	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

PC11Y_HUMAN
NC score	0.055381 (rank : 756)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	582	Target Neighborhood Hits	205	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

PKD1_HUMAN
NC score	0.055316 (rank : 757)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	582	Target Neighborhood Hits	387	Shared Neighborhood Hits	31
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

HPLN3_HUMAN
NC score	0.055278 (rank : 758)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	582	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

LRRN1_HUMAN
NC score	0.055192 (rank : 759)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	582	Target Neighborhood Hits	518	Shared Neighborhood Hits	33
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

GP1BB_MOUSE
NC score	0.055174 (rank : 760)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	582	Target Neighborhood Hits	136	Shared Neighborhood Hits	10
SwissProt Accessions	P56400	Gene names	Gp1bb
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (CD42c antigen).

LRFN3_MOUSE
NC score	0.055022 (rank : 761)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	582	Target Neighborhood Hits	455	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN5_MOUSE
NC score	0.054817 (rank : 762)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	582	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRC52_HUMAN
NC score	0.054680 (rank : 763)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	582	Target Neighborhood Hits	229	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N7C0, Q5T9K5	Gene names	LRRC52
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 52 precursor.

LRFN4_MOUSE
NC score	0.054667 (rank : 764)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	582	Target Neighborhood Hits	442	Shared Neighborhood Hits	29
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

TR19L_MOUSE
NC score	0.054665 (rank : 765)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	582	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

KR121_HUMAN
NC score	0.054367 (rank : 766)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	582	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P59990	Gene names	KRTAP12-1, KAP12.1, KRTAP12.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-1 (Keratin-associated protein 12.1) (High sulfur keratin-associated protein 12.1).

HPLN1_MOUSE
NC score	0.054294 (rank : 767)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	582	Target Neighborhood Hits	64	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

TSG6_MOUSE
NC score	0.054292 (rank : 768)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	582	Target Neighborhood Hits	91	Shared Neighborhood Hits	19
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

AMGO3_HUMAN
NC score	0.054273 (rank : 769)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	582	Target Neighborhood Hits	276	Shared Neighborhood Hits	16
SwissProt Accessions	Q86WK7, Q96JH6	Gene names	AMIGO3, ALI3, KIAA1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

LRFN5_HUMAN
NC score	0.054265 (rank : 770)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	582	Target Neighborhood Hits	464	Shared Neighborhood Hits	22
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

PGCA_MOUSE
NC score	0.054263 (rank : 771)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	582	Target Neighborhood Hits	643	Shared Neighborhood Hits	56
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

TSG6_HUMAN
NC score	0.054247 (rank : 772)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	582	Target Neighborhood Hits	91	Shared Neighborhood Hits	20
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

HPLN1_HUMAN
NC score	0.054227 (rank : 773)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	582	Target Neighborhood Hits	67	Shared Neighborhood Hits	12
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

LRC55_MOUSE
NC score	0.054155 (rank : 774)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	582	Target Neighborhood Hits	254	Shared Neighborhood Hits	10
SwissProt Accessions	Q3UY51	Gene names	Lrrc55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

LRRN3_HUMAN
NC score	0.054147 (rank : 775)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	582	Target Neighborhood Hits	461	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

TR10B_MOUSE
NC score	0.054106 (rank : 776)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	582	Target Neighborhood Hits	76	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

MT1M_HUMAN
NC score	0.054018 (rank : 777)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	582	Target Neighborhood Hits	72	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

LRRN1_MOUSE
NC score	0.054001 (rank : 778)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	582	Target Neighborhood Hits	508	Shared Neighborhood Hits	32
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

SPR2E_HUMAN
NC score	0.053959 (rank : 779)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	582	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

PROP_MOUSE
NC score	0.053922 (rank : 780)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	582	Target Neighborhood Hits	165	Shared Neighborhood Hits	49
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

GP110_MOUSE
NC score	0.053878 (rank : 781)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	582	Target Neighborhood Hits	92	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

OBSL1_HUMAN
NC score	0.053712 (rank : 782)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	582	Target Neighborhood Hits	354	Shared Neighborhood Hits	18
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

LRFN3_HUMAN
NC score	0.053651 (rank : 783)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	582	Target Neighborhood Hits	444	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

ATS9_HUMAN
NC score	0.053597 (rank : 784)	θ value	6.88961 (rank : 545)
Query Neighborhood Hits	582	Target Neighborhood Hits	219	Shared Neighborhood Hits	99
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

LRFN2_MOUSE
NC score	0.053570 (rank : 785)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	582	Target Neighborhood Hits	450	Shared Neighborhood Hits	23
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

ADEC1_MOUSE
NC score	0.053547 (rank : 786)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	582	Target Neighborhood Hits	85	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

LRC55_HUMAN
NC score	0.053236 (rank : 787)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	582	Target Neighborhood Hits	257	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZSA7	Gene names	LRRC55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

SO1B3_HUMAN
NC score	0.053111 (rank : 788)	θ value	1.06291 (rank : 424)
Query Neighborhood Hits	582	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

TNR18_HUMAN
NC score	0.053107 (rank : 789)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	582	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

GP110_HUMAN
NC score	0.053100 (rank : 790)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	582	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

PRP2_MOUSE
NC score	0.053094 (rank : 791)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	582	Target Neighborhood Hits	347	Shared Neighborhood Hits	47
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SO1A2_HUMAN
NC score	0.052977 (rank : 792)	θ value	1.38821 (rank : 436)
Query Neighborhood Hits	582	Target Neighborhood Hits	40	Shared Neighborhood Hits	31
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

SO1B2_MOUSE
NC score	0.052949 (rank : 793)	θ value	0.813845 (rank : 404)
Query Neighborhood Hits	582	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJL3, Q9JI79, Q9JJJ1	Gene names	Slco1b2, Slc21a10
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B2 (Solute carrier family 21 member 10) (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6).

ENTK_MOUSE
NC score	0.052846 (rank : 794)	θ value	0.00869519 (rank : 269)
Query Neighborhood Hits	582	Target Neighborhood Hits	338	Shared Neighborhood Hits	68
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

SO1B1_HUMAN
NC score	0.052665 (rank : 795)	θ value	0.62314 (rank : 396)
Query Neighborhood Hits	582	Target Neighborhood Hits	43	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

LRRN5_HUMAN
NC score	0.052644 (rank : 796)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	582	Target Neighborhood Hits	493	Shared Neighborhood Hits	26
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

NRCAM_HUMAN
NC score	0.052618 (rank : 797)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	582	Target Neighborhood Hits	439	Shared Neighborhood Hits	41
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NPHN_HUMAN
NC score	0.052558 (rank : 798)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	582	Target Neighborhood Hits	362	Shared Neighborhood Hits	30
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

SO4A1_MOUSE
NC score	0.052495 (rank : 799)	θ value	0.47712 (rank : 380)
Query Neighborhood Hits	582	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

COCA1_MOUSE
NC score	0.052492 (rank : 800)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	582	Target Neighborhood Hits	467	Shared Neighborhood Hits	53
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

ADEC1_HUMAN
NC score	0.052361 (rank : 801)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	582	Target Neighborhood Hits	80	Shared Neighborhood Hits	35
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

CDN2B_HUMAN
NC score	0.052263 (rank : 802)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	582	Target Neighborhood Hits	196	Shared Neighborhood Hits	10
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

LRC3B_HUMAN
NC score	0.052250 (rank : 803)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	582	Target Neighborhood Hits	215	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PB8	Gene names	LRRC3B, LRP15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

LRC3B_MOUSE
NC score	0.052238 (rank : 804)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	582	Target Neighborhood Hits	215	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VCH9	Gene names	Lrrc3b, Lrp15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

COCA1_HUMAN
NC score	0.052155 (rank : 805)	θ value	1.81305 (rank : 442)
Query Neighborhood Hits	582	Target Neighborhood Hits	458	Shared Neighborhood Hits	50
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

IBP1_MOUSE
NC score	0.052029 (rank : 806)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	582	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

TACD2_HUMAN
NC score	0.052008 (rank : 807)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	582	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

NFASC_HUMAN
NC score	0.051930 (rank : 808)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	582	Target Neighborhood Hits	497	Shared Neighborhood Hits	50
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

CD2A1_MOUSE
NC score	0.051925 (rank : 809)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	582	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CT075_HUMAN
NC score	0.051704 (rank : 810)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	582	Target Neighborhood Hits	387	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

SHAN1_HUMAN
NC score	0.051623 (rank : 811)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	582	Target Neighborhood Hits	1041	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

LRRC3_MOUSE
NC score	0.051621 (rank : 812)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	582	Target Neighborhood Hits	236	Shared Neighborhood Hits	10
SwissProt Accessions	P59034	Gene names	Lrrc3
Domain Architecture
Description	Leucine-rich repeat-containing protein 3 precursor.

PGLB_HUMAN
NC score	0.051339 (rank : 813)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	582	Target Neighborhood Hits	250	Shared Neighborhood Hits	11
SwissProt Accessions	Q99645, Q8NEJ5	Gene names	DSPG3, PGLB
Domain Architecture
Description	Dermatan sulfate proteoglycan 3 precursor (Epiphycan) (Small chondroitin/dermatan sulfate proteoglycan) (Proteoglycan-Lb) (PG-Lb).

NRCAM_MOUSE
NC score	0.051233 (rank : 814)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	582	Target Neighborhood Hits	432	Shared Neighborhood Hits	41
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

TMG1_HUMAN
NC score	0.051217 (rank : 815)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	582	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

CAD13_HUMAN
NC score	0.050861 (rank : 816)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	582	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	P55290, Q8TBX3	Gene names	CDH13, CDHH
Domain Architecture
Description	Cadherin-13 precursor (Truncated-cadherin) (T-cadherin) (T-cad) (Heart-cadherin) (H-cadherin) (P105).

FREM1_HUMAN
NC score	0.050860 (rank : 817)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	582	Target Neighborhood Hits	170	Shared Neighborhood Hits	19
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

CT075_MOUSE
NC score	0.050807 (rank : 818)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	582	Target Neighborhood Hits	358	Shared Neighborhood Hits	29
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

L1CAM_HUMAN
NC score	0.050775 (rank : 819)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	582	Target Neighborhood Hits	457	Shared Neighborhood Hits	43
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CAD13_MOUSE
NC score	0.050724 (rank : 820)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	582	Target Neighborhood Hits	156	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTR5	Gene names	Cdh13
Domain Architecture
Description	Cadherin-13 precursor (Truncated-cadherin) (T-cadherin) (T-cad) (Heart-cadherin) (H-cadherin).

L1CAM_MOUSE
NC score	0.050657 (rank : 821)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	582	Target Neighborhood Hits	457	Shared Neighborhood Hits	41
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

ROBO3_HUMAN
NC score	0.050467 (rank : 822)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	582	Target Neighborhood Hits	570	Shared Neighborhood Hits	58
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

PCD12_MOUSE
NC score	0.050350 (rank : 823)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	582	Target Neighborhood Hits	199	Shared Neighborhood Hits	11
SwissProt Accessions	O55134	Gene names	Pcdh12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

MDGA1_HUMAN
NC score	0.050320 (rank : 824)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	582	Target Neighborhood Hits	358	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

LRRC4_HUMAN
NC score	0.050244 (rank : 825)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	582	Target Neighborhood Hits	444	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

FREM1_MOUSE
NC score	0.050159 (rank : 826)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	582	Target Neighborhood Hits	163	Shared Neighborhood Hits	18
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

LRC52_MOUSE
NC score	0.050154 (rank : 827)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	582	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q5M8M9	Gene names	Lrrc52
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 52 precursor.

SO1A5_MOUSE
NC score	0.050006 (rank : 828)	θ value	1.06291 (rank : 423)
Query Neighborhood Hits	582	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	Q91YY5, Q91XS2	Gene names	Slco1a5, Oatp3, Slc21a7
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A5 (Solute carrier family 21 member 7) (Sodium-independent organic anion transporter 3) (Organic anion-transporting polypeptide 3).

SO1C1_MOUSE
NC score	0.049773 (rank : 829)	θ value	3.0926 (rank : 487)
Query Neighborhood Hits	582	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

SO1A4_MOUSE
NC score	0.048980 (rank : 830)	θ value	1.06291 (rank : 422)
Query Neighborhood Hits	582	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EP96	Gene names	Slco1a4, Oatp2, Slc21a5
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A4 (Solute carrier family 21 member 5) (Sodium-independent organic anion- transporting polypeptide 2).

SO1A1_MOUSE
NC score	0.048444 (rank : 831)	θ value	1.06291 (rank : 421)
Query Neighborhood Hits	582	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SPY1_MOUSE
NC score	0.048003 (rank : 832)	θ value	4.03905 (rank : 506)
Query Neighborhood Hits	582	Target Neighborhood Hits	57	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

SO1A6_MOUSE
NC score	0.047281 (rank : 833)	θ value	5.27518 (rank : 535)
Query Neighborhood Hits	582	Target Neighborhood Hits	34	Shared Neighborhood Hits	27
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

SO1C1_HUMAN
NC score	0.046876 (rank : 834)	θ value	5.27518 (rank : 536)
Query Neighborhood Hits	582	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYB5	Gene names	SLCO1C1, OATPF, SLC21A14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5).

EPHB4_HUMAN
NC score	0.046813 (rank : 835)	θ value	0.813845 (rank : 399)
Query Neighborhood Hits	582	Target Neighborhood Hits	1056	Shared Neighborhood Hits	140
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

ATS20_HUMAN
NC score	0.046018 (rank : 836)	θ value	0.125558 (rank : 331)
Query Neighborhood Hits	582	Target Neighborhood Hits	192	Shared Neighborhood Hits	77
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

SPY1_HUMAN
NC score	0.045232 (rank : 837)	θ value	6.88961 (rank : 565)
Query Neighborhood Hits	582	Target Neighborhood Hits	64	Shared Neighborhood Hits	42
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

TARSH_HUMAN
NC score	0.045213 (rank : 838)	θ value	1.38821 (rank : 438)
Query Neighborhood Hits	582	Target Neighborhood Hits	768	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

PROP_HUMAN
NC score	0.040884 (rank : 839)	θ value	5.27518 (rank : 532)
Query Neighborhood Hits	582	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

LRTM3_HUMAN
NC score	0.040653 (rank : 840)	θ value	3.0926 (rank : 478)
Query Neighborhood Hits	582	Target Neighborhood Hits	276	Shared Neighborhood Hits	13
SwissProt Accessions	Q86VH5, Q6N0A3	Gene names	LRRTM3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 3 precursor.

COGA1_HUMAN
NC score	0.040592 (rank : 841)	θ value	0.0252991 (rank : 292)
Query Neighborhood Hits	582	Target Neighborhood Hits	345	Shared Neighborhood Hits	47
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

MDC1_HUMAN
NC score	0.040464 (rank : 842)	θ value	0.0148317 (rank : 282)
Query Neighborhood Hits	582	Target Neighborhood Hits	1446	Shared Neighborhood Hits	66
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

EHMT2_MOUSE
NC score	0.040178 (rank : 843)	θ value	0.365318 (rank : 364)
Query Neighborhood Hits	582	Target Neighborhood Hits	750	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

LRTM3_MOUSE
NC score	0.039842 (rank : 844)	θ value	5.27518 (rank : 521)
Query Neighborhood Hits	582	Target Neighborhood Hits	290	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZ81, Q3TQA3, Q8BGJ7	Gene names	Lrrtm3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 3 precursor.

NACAM_MOUSE
NC score	0.039678 (rank : 845)	θ value	0.365318 (rank : 367)
Query Neighborhood Hits	582	Target Neighborhood Hits	1866	Shared Neighborhood Hits	101
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ATS16_MOUSE
NC score	0.036938 (rank : 846)	θ value	6.88961 (rank : 543)
Query Neighborhood Hits	582	Target Neighborhood Hits	179	Shared Neighborhood Hits	67
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

SRPX_MOUSE
NC score	0.035998 (rank : 847)	θ value	0.813845 (rank : 406)
Query Neighborhood Hits	582	Target Neighborhood Hits	75	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

HYAL3_MOUSE
NC score	0.035818 (rank : 848)	θ value	8.99809 (rank : 572)
Query Neighborhood Hits	582	Target Neighborhood Hits	44	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

K0319_MOUSE
NC score	0.035505 (rank : 849)	θ value	0.279714 (rank : 354)
Query Neighborhood Hits	582	Target Neighborhood Hits	134	Shared Neighborhood Hits	24
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

SRPX_HUMAN
NC score	0.035213 (rank : 850)	θ value	0.47712 (rank : 382)
Query Neighborhood Hits	582	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

ATS3_HUMAN
NC score	0.034688 (rank : 851)	θ value	2.36792 (rank : 456)
Query Neighborhood Hits	582	Target Neighborhood Hits	179	Shared Neighborhood Hits	63
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS4_MOUSE
NC score	0.033720 (rank : 852)	θ value	6.88961 (rank : 544)
Query Neighborhood Hits	582	Target Neighborhood Hits	145	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

MAGE1_HUMAN
NC score	0.033549 (rank : 853)	θ value	0.0113563 (rank : 273)
Query Neighborhood Hits	582	Target Neighborhood Hits	1389	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NEU2_HUMAN
NC score	0.033496 (rank : 854)	θ value	8.99809 (rank : 577)
Query Neighborhood Hits	582	Target Neighborhood Hits	37	Shared Neighborhood Hits	30
SwissProt Accessions	P01185, O14935	Gene names	AVP, ARVP, VP
Domain Architecture
Description	Vasopressin-neurophysin 2-copeptin precursor (AVP-NPII) [Contains: Arg-vasopressin; Neurophysin 2 (Neurophysin-II); Copeptin].

GFRA3_HUMAN
NC score	0.033437 (rank : 855)	θ value	0.0252991 (rank : 294)
Query Neighborhood Hits	582	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

ERBB3_HUMAN
NC score	0.032694 (rank : 856)	θ value	1.06291 (rank : 418)
Query Neighborhood Hits	582	Target Neighborhood Hits	918	Shared Neighborhood Hits	105
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

MLL3_HUMAN
NC score	0.032688 (rank : 857)	θ value	5.27518 (rank : 524)
Query Neighborhood Hits	582	Target Neighborhood Hits	1644	Shared Neighborhood Hits	117
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

EPHB6_HUMAN
NC score	0.032251 (rank : 858)	θ value	1.06291 (rank : 417)
Query Neighborhood Hits	582	Target Neighborhood Hits	912	Shared Neighborhood Hits	87
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

MUC1_MOUSE
NC score	0.031361 (rank : 859)	θ value	2.36792 (rank : 463)
Query Neighborhood Hits	582	Target Neighborhood Hits	388	Shared Neighborhood Hits	36
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MDC1_MOUSE
NC score	0.031143 (rank : 860)	θ value	5.27518 (rank : 523)
Query Neighborhood Hits	582	Target Neighborhood Hits	998	Shared Neighborhood Hits	72
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

ATS8_MOUSE
NC score	0.030845 (rank : 861)	θ value	4.03905 (rank : 492)
Query Neighborhood Hits	582	Target Neighborhood Hits	139	Shared Neighborhood Hits	52
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

F19A4_MOUSE
NC score	0.030568 (rank : 862)	θ value	0.365318 (rank : 365)
Query Neighborhood Hits	582	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TPG5, Q5FWC0, Q8BV02	Gene names	Fam19a4, Tafa4
Domain Architecture	No domain graphic available
Description	Protein FAM19A4 precursor (Chemokine-like protein TAFA-4).

MUC1_HUMAN
NC score	0.030355 (rank : 863)	θ value	0.813845 (rank : 403)
Query Neighborhood Hits	582	Target Neighborhood Hits	975	Shared Neighborhood Hits	68
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NCOA6_MOUSE
NC score	0.030268 (rank : 864)	θ value	5.27518 (rank : 528)
Query Neighborhood Hits	582	Target Neighborhood Hits	1076	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

EPHA1_HUMAN
NC score	0.029713 (rank : 865)	θ value	1.81305 (rank : 444)
Query Neighborhood Hits	582	Target Neighborhood Hits	997	Shared Neighborhood Hits	111
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

ENPP2_MOUSE
NC score	0.028858 (rank : 866)	θ value	8.99809 (rank : 571)
Query Neighborhood Hits	582	Target Neighborhood Hits	66	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

F19A4_HUMAN
NC score	0.027821 (rank : 867)	θ value	2.36792 (rank : 459)
Query Neighborhood Hits	582	Target Neighborhood Hits	21	Shared Neighborhood Hits	17
SwissProt Accessions	Q96LR4	Gene names	FAM19A4, TAFA4
Domain Architecture	No domain graphic available
Description	Protein FAM19A4 precursor (Chemokine-like protein TAFA-4).

LEUK_HUMAN
NC score	0.027584 (rank : 868)	θ value	5.27518 (rank : 519)
Query Neighborhood Hits	582	Target Neighborhood Hits	213	Shared Neighborhood Hits	25
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

SPR1B_MOUSE
NC score	0.026466 (rank : 869)	θ value	0.163984 (rank : 344)
Query Neighborhood Hits	582	Target Neighborhood Hits	395	Shared Neighborhood Hits	39
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

F19A2_MOUSE
NC score	0.026361 (rank : 870)	θ value	6.88961 (rank : 552)
Query Neighborhood Hits	582	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TPG7, Q5M9Q3	Gene names	Fam19a2, Tafa2
Domain Architecture	No domain graphic available
Description	Protein FAM19A2 precursor (Chemokine-like protein TAFA-2).

F19A2_HUMAN
NC score	0.026329 (rank : 871)	θ value	6.88961 (rank : 551)
Query Neighborhood Hits	582	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N3H0, Q4G0R9, Q68DK0, Q6GTX6	Gene names	FAM19A2, TAFA2
Domain Architecture	No domain graphic available
Description	Protein FAM19A2 precursor (Chemokine-like protein TAFA-2).

RFX1_HUMAN
NC score	0.025731 (rank : 872)	θ value	0.62314 (rank : 395)
Query Neighborhood Hits	582	Target Neighborhood Hits	256	Shared Neighborhood Hits	36
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

EPHA3_MOUSE
NC score	0.025673 (rank : 873)	θ value	1.06291 (rank : 416)
Query Neighborhood Hits	582	Target Neighborhood Hits	1009	Shared Neighborhood Hits	84
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

NCOA6_HUMAN
NC score	0.025470 (rank : 874)	θ value	5.27518 (rank : 527)
Query Neighborhood Hits	582	Target Neighborhood Hits	1202	Shared Neighborhood Hits	69
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

EPHA1_MOUSE
NC score	0.025152 (rank : 875)	θ value	0.0431538 (rank : 308)
Query Neighborhood Hits	582	Target Neighborhood Hits	958	Shared Neighborhood Hits	94
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

SPR1A_MOUSE
NC score	0.024729 (rank : 876)	θ value	0.813845 (rank : 405)
Query Neighborhood Hits	582	Target Neighborhood Hits	343	Shared Neighborhood Hits	32
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

EPHA3_HUMAN
NC score	0.024628 (rank : 877)	θ value	0.62314 (rank : 389)
Query Neighborhood Hits	582	Target Neighborhood Hits	1005	Shared Neighborhood Hits	89
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

SON_MOUSE
NC score	0.024210 (rank : 878)	θ value	5.27518 (rank : 537)
Query Neighborhood Hits	582	Target Neighborhood Hits	957	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SON_HUMAN
NC score	0.024034 (rank : 879)	θ value	6.88961 (rank : 564)
Query Neighborhood Hits	582	Target Neighborhood Hits	1568	Shared Neighborhood Hits	85
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

EPHB6_MOUSE
NC score	0.023608 (rank : 880)	θ value	6.88961 (rank : 550)
Query Neighborhood Hits	582	Target Neighborhood Hits	906	Shared Neighborhood Hits	71
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPHA2_HUMAN
NC score	0.023474 (rank : 881)	θ value	0.47712 (rank : 375)
Query Neighborhood Hits	582	Target Neighborhood Hits	1021	Shared Neighborhood Hits	88
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

IER5_MOUSE
NC score	0.023415 (rank : 882)	θ value	2.36792 (rank : 460)
Query Neighborhood Hits	582	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

ENPP2_HUMAN
NC score	0.023005 (rank : 883)	θ value	6.88961 (rank : 548)
Query Neighborhood Hits	582	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

F19A5_HUMAN
NC score	0.022971 (rank : 884)	θ value	1.81305 (rank : 446)
Query Neighborhood Hits	582	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z5A7, O95902, Q5H9C4, Q6UWC9, Q8IXR8	Gene names	FAM19A5, TAFA5
Domain Architecture	No domain graphic available
Description	Protein FAM19A5 precursor (Chemokine-like protein TAFA-5).

F19A5_MOUSE
NC score	0.022971 (rank : 885)	θ value	1.81305 (rank : 447)
Query Neighborhood Hits	582	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WE9, Q8C1V6	Gene names	Fam19a5, Tafa5
Domain Architecture	No domain graphic available
Description	Protein FAM19A5 precursor (Chemokine-like protein TAFA-5).

CR1_HUMAN
NC score	0.021437 (rank : 886)	θ value	5.27518 (rank : 512)
Query Neighborhood Hits	582	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CEL_HUMAN
NC score	0.020986 (rank : 887)	θ value	0.0148317 (rank : 277)
Query Neighborhood Hits	582	Target Neighborhood Hits	896	Shared Neighborhood Hits	53
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

DOT1L_HUMAN
NC score	0.020670 (rank : 888)	θ value	5.27518 (rank : 513)
Query Neighborhood Hits	582	Target Neighborhood Hits	660	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

SPEG_HUMAN
NC score	0.020226 (rank : 889)	θ value	0.365318 (rank : 369)
Query Neighborhood Hits	582	Target Neighborhood Hits	1762	Shared Neighborhood Hits	90
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

OBSCN_HUMAN
NC score	0.019257 (rank : 890)	θ value	5.27518 (rank : 529)
Query Neighborhood Hits	582	Target Neighborhood Hits	1931	Shared Neighborhood Hits	82
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

GFRA3_MOUSE
NC score	0.018454 (rank : 891)	θ value	6.88961 (rank : 553)
Query Neighborhood Hits	582	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O35118, O35325, O55243, Q6NZC2, Q8C8L9	Gene names	Gfra3
Domain Architecture	No domain graphic available
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

TS13_MOUSE
NC score	0.018433 (rank : 892)	θ value	2.36792 (rank : 469)
Query Neighborhood Hits	582	Target Neighborhood Hits	191	Shared Neighborhood Hits	10
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

HEMGN_MOUSE
NC score	0.018352 (rank : 893)	θ value	1.38821 (rank : 433)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ERZ0, Q3TAE6, Q80YT2, Q8CF29	Gene names	Hemgn, Ndr
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (mNDR).

MAVS_HUMAN
NC score	0.017961 (rank : 894)	θ value	6.88961 (rank : 555)
Query Neighborhood Hits	582	Target Neighborhood Hits	271	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

COIA1_HUMAN
NC score	0.017587 (rank : 895)	θ value	3.0926 (rank : 477)
Query Neighborhood Hits	582	Target Neighborhood Hits	447	Shared Neighborhood Hits	45
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

EPHB1_HUMAN
NC score	0.017423 (rank : 896)	θ value	6.88961 (rank : 549)
Query Neighborhood Hits	582	Target Neighborhood Hits	988	Shared Neighborhood Hits	87
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

T22D4_HUMAN
NC score	0.016902 (rank : 897)	θ value	1.38821 (rank : 437)
Query Neighborhood Hits	582	Target Neighborhood Hits	403	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

DGKI_HUMAN
NC score	0.016740 (rank : 898)	θ value	0.62314 (rank : 387)
Query Neighborhood Hits	582	Target Neighborhood Hits	609	Shared Neighborhood Hits	16
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

OGFR_HUMAN
NC score	0.016284 (rank : 899)	θ value	4.03905 (rank : 501)
Query Neighborhood Hits	582	Target Neighborhood Hits	1582	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BSN_HUMAN
NC score	0.015618 (rank : 900)	θ value	8.99809 (rank : 567)
Query Neighborhood Hits	582	Target Neighborhood Hits	1537	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

TACC2_HUMAN
NC score	0.015371 (rank : 901)	θ value	3.0926 (rank : 488)
Query Neighborhood Hits	582	Target Neighborhood Hits	856	Shared Neighborhood Hits	42
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

MTSS1_HUMAN
NC score	0.015295 (rank : 902)	θ value	8.99809 (rank : 576)
Query Neighborhood Hits	582	Target Neighborhood Hits	504	Shared Neighborhood Hits	33
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

SETBP_HUMAN
NC score	0.015038 (rank : 903)	θ value	4.03905 (rank : 505)
Query Neighborhood Hits	582	Target Neighborhood Hits	305	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SC24C_HUMAN
NC score	0.013677 (rank : 904)	θ value	3.0926 (rank : 486)
Query Neighborhood Hits	582	Target Neighborhood Hits	662	Shared Neighborhood Hits	46
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

COIA1_MOUSE
NC score	0.012649 (rank : 905)	θ value	6.88961 (rank : 547)
Query Neighborhood Hits	582	Target Neighborhood Hits	481	Shared Neighborhood Hits	42
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

LPP_HUMAN
NC score	0.012569 (rank : 906)	θ value	0.47712 (rank : 378)
Query Neighborhood Hits	582	Target Neighborhood Hits	775	Shared Neighborhood Hits	52
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

COAA1_MOUSE
NC score	0.012523 (rank : 907)	θ value	6.88961 (rank : 546)
Query Neighborhood Hits	582	Target Neighborhood Hits	286	Shared Neighborhood Hits	29
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

CO4A3_HUMAN
NC score	0.012489 (rank : 908)	θ value	3.0926 (rank : 476)
Query Neighborhood Hits	582	Target Neighborhood Hits	421	Shared Neighborhood Hits	37
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

NUFP1_HUMAN
NC score	0.011928 (rank : 909)	θ value	4.03905 (rank : 500)
Query Neighborhood Hits	582	Target Neighborhood Hits	193	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

MILK1_MOUSE
NC score	0.011859 (rank : 910)	θ value	6.88961 (rank : 556)
Query Neighborhood Hits	582	Target Neighborhood Hits	788	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SRBP1_MOUSE
NC score	0.011046 (rank : 911)	θ value	2.36792 (rank : 466)
Query Neighborhood Hits	582	Target Neighborhood Hits	384	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRRM2_MOUSE
NC score	0.010745 (rank : 912)	θ value	5.27518 (rank : 538)
Query Neighborhood Hits	582	Target Neighborhood Hits	1470	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

RGS3_HUMAN
NC score	0.010685 (rank : 913)	θ value	0.21417 (rank : 347)
Query Neighborhood Hits	582	Target Neighborhood Hits	1375	Shared Neighborhood Hits	64
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

LY6H_HUMAN
NC score	0.010336 (rank : 914)	θ value	6.88961 (rank : 554)
Query Neighborhood Hits	582	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O94772	Gene names	LY6H
Domain Architecture
Description	Lymphocyte antigen Ly-6H precursor.

RFX2_HUMAN
NC score	0.009482 (rank : 915)	θ value	4.03905 (rank : 502)
Query Neighborhood Hits	582	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	P48378	Gene names	RFX2
Domain Architecture
Description	DNA-binding protein RFX2.

SOX30_MOUSE
NC score	0.009477 (rank : 916)	θ value	0.47712 (rank : 381)
Query Neighborhood Hits	582	Target Neighborhood Hits	374	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

UPK3A_MOUSE
NC score	0.009074 (rank : 917)	θ value	6.88961 (rank : 566)
Query Neighborhood Hits	582	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKX8	Gene names	Upk3a, Upk3
Domain Architecture	No domain graphic available
Description	Uroplakin-3A precursor (Uroplakin III) (UPIII).

PK1L1_HUMAN
NC score	0.008738 (rank : 918)	θ value	3.0926 (rank : 485)
Query Neighborhood Hits	582	Target Neighborhood Hits	140	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

UPK3A_HUMAN
NC score	0.008138 (rank : 919)	θ value	8.99809 (rank : 581)
Query Neighborhood Hits	582	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O75631, O60261	Gene names	UPK3A, UPK3
Domain Architecture	No domain graphic available
Description	Uroplakin-3A precursor (Uroplakin III) (UPIII).

PARC_HUMAN
NC score	0.007839 (rank : 920)	θ value	5.27518 (rank : 531)
Query Neighborhood Hits	582	Target Neighborhood Hits	148	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

RP1L1_MOUSE
NC score	0.006927 (rank : 921)	θ value	5.27518 (rank : 533)
Query Neighborhood Hits	582	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

LOXL3_MOUSE
NC score	0.006842 (rank : 922)	θ value	0.62314 (rank : 392)
Query Neighborhood Hits	582	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z175, Q9JJ39	Gene names	Loxl3, Lor2
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3) (Lysyl oxidase-related protein 2).

RIMB1_HUMAN
NC score	0.006231 (rank : 923)	θ value	4.03905 (rank : 503)
Query Neighborhood Hits	582	Target Neighborhood Hits	1479	Shared Neighborhood Hits	52
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

NUP98_HUMAN
NC score	0.006224 (rank : 924)	θ value	8.99809 (rank : 578)
Query Neighborhood Hits	582	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	P52948, Q8IUT2, Q8WYB0, Q96E54, Q9H3Q4, Q9NT02, Q9UF57, Q9UHX0, Q9Y6J4, Q9Y6J5	Gene names	NUP98
Domain Architecture
Description	Nuclear pore complex protein Nup98-Nup96 precursor [Contains: Nuclear pore complex protein Nup98 (Nucleoporin Nup98) (98 kDa nucleoporin); Nuclear pore complex protein Nup96 (Nucleoporin Nup96) (96 kDa nucleoporin)].

C163A_MOUSE
NC score	0.006059 (rank : 925)	θ value	8.99809 (rank : 568)
Query Neighborhood Hits	582	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	Q2VLH6, Q2VLH5, Q99MX8	Gene names	Cd163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) [Contains: Soluble CD163 (sCD163)].

SEPT9_HUMAN
NC score	0.005608 (rank : 926)	θ value	6.88961 (rank : 560)
Query Neighborhood Hits	582	Target Neighborhood Hits	706	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

IRS1_HUMAN
NC score	0.005491 (rank : 927)	θ value	4.03905 (rank : 496)
Query Neighborhood Hits	582	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

K1802_MOUSE
NC score	0.004612 (rank : 928)	θ value	4.03905 (rank : 497)
Query Neighborhood Hits	582	Target Neighborhood Hits	1596	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SH23A_HUMAN
NC score	0.004557 (rank : 929)	θ value	6.88961 (rank : 561)
Query Neighborhood Hits	582	Target Neighborhood Hits	149	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BRG2, Q9Y2X4	Gene names	SH2D3A, NSP1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3A (Novel SH2-containing protein 1).

SIRT1_HUMAN
NC score	0.002812 (rank : 930)	θ value	8.99809 (rank : 579)
Query Neighborhood Hits	582	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q96EB6, Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0	Gene names	SIRT1, SIR2L1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (hSIRT1) (hSIR2) (SIR2-like protein 1).

KCNH3_MOUSE
NC score	0.002808 (rank : 931)	θ value	4.03905 (rank : 498)
Query Neighborhood Hits	582	Target Neighborhood Hits	133	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

RPGF1_HUMAN
NC score	0.002539 (rank : 932)	θ value	5.27518 (rank : 534)
Query Neighborhood Hits	582	Target Neighborhood Hits	262	Shared Neighborhood Hits	13
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SIPA1_MOUSE
NC score	0.001545 (rank : 933)	θ value	6.88961 (rank : 562)
Query Neighborhood Hits	582	Target Neighborhood Hits	158	Shared Neighborhood Hits	4
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

TRI66_MOUSE
NC score	0.001280 (rank : 934)	θ value	5.27518 (rank : 540)
Query Neighborhood Hits	582	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

AAK1_HUMAN
NC score	0.000208 (rank : 935)	θ value	1.38821 (rank : 427)
Query Neighborhood Hits	582	Target Neighborhood Hits	1077	Shared Neighborhood Hits	46
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

PTN18_MOUSE
NC score	-0.000145 (rank : 936)	θ value	6.88961 (rank : 557)
Query Neighborhood Hits	582	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

AAK1_MOUSE
NC score	-0.001543 (rank : 937)	θ value	4.03905 (rank : 490)
Query Neighborhood Hits	582	Target Neighborhood Hits	1051	Shared Neighborhood Hits	49
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

PTPR2_MOUSE
NC score	-0.001551 (rank : 938)	θ value	6.88961 (rank : 558)
Query Neighborhood Hits	582	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

RORG_HUMAN
NC score	-0.001811 (rank : 939)	θ value	6.88961 (rank : 559)
Query Neighborhood Hits	582	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

KSYK_MOUSE
NC score	-0.001908 (rank : 940)	θ value	8.99809 (rank : 573)
Query Neighborhood Hits	582	Target Neighborhood Hits	944	Shared Neighborhood Hits	28
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

CD2L7_HUMAN
NC score	-0.003032 (rank : 941)	θ value	3.0926 (rank : 474)
Query Neighborhood Hits	582	Target Neighborhood Hits	1275	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CAMKV_HUMAN
NC score	-0.004401 (rank : 942)	θ value	0.163984 (rank : 339)
Query Neighborhood Hits	582	Target Neighborhood Hits	1084	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

BMP2K_HUMAN
NC score	-0.005938 (rank : 943)	θ value	5.27518 (rank : 510)
Query Neighborhood Hits	582	Target Neighborhood Hits	867	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

NKX26_MOUSE
NC score	-0.006194 (rank : 944)	θ value	2.36792 (rank : 464)
Query Neighborhood Hits	582	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	P43688	Gene names	Nkx2-6, Nkx-2.6, Nkx2f
Domain Architecture
Description	Homeobox protein Nkx-2.6 (Homeobox protein NK-2 homolog F).

MAST4_HUMAN
NC score	-0.006658 (rank : 945)	θ value	3.0926 (rank : 479)
Query Neighborhood Hits	582	Target Neighborhood Hits	1804	Shared Neighborhood Hits	79
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ZN687_MOUSE
NC score	-0.008747 (rank : 946)	θ value	8.99809 (rank : 582)
Query Neighborhood Hits	582	Target Neighborhood Hits	913	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ZN677_HUMAN
NC score	-0.011531 (rank : 947)	θ value	2.36792 (rank : 471)
Query Neighborhood Hits	582	Target Neighborhood Hits	761	Shared Neighborhood Hits	21
SwissProt Accessions	Q86XU0	Gene names	ZNF677
Domain Architecture	No domain graphic available
Description	Zinc finger protein 677.

ZN184_HUMAN
NC score	-0.011731 (rank : 948)	θ value	4.03905 (rank : 508)
Query Neighborhood Hits	582	Target Neighborhood Hits	811	Shared Neighborhood Hits	24
SwissProt Accessions	Q99676, O60792, Q8TBA9	Gene names	ZNF184
Domain Architecture
Description	Zinc finger protein 184.

SCRT1_HUMAN
NC score	-0.012196 (rank : 949)	θ value	0.279714 (rank : 357)
Query Neighborhood Hits	582	Target Neighborhood Hits	706	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BWW7, Q96C52	Gene names	SCRT1
Domain Architecture	No domain graphic available
Description	Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (Scratch 1) (SCRT) (hScrt).

SCRT1_MOUSE
NC score	-0.013082 (rank : 950)	θ value	4.03905 (rank : 504)
Query Neighborhood Hits	582	Target Neighborhood Hits	703	Shared Neighborhood Hits	11
SwissProt Accessions	Q99M85	Gene names	Scrt1
Domain Architecture	No domain graphic available
Description	Transcriptional repressor scratch 1 (Scratch homolog 1 zinc finger protein) (Scratch 1) (SCRT) (mScrt).

ZN553_MOUSE
NC score	-0.013738 (rank : 951)	θ value	4.03905 (rank : 509)
Query Neighborhood Hits	582	Target Neighborhood Hits	744	Shared Neighborhood Hits	15
SwissProt Accessions	Q3US17, Q3UFP3, Q8R0V0, Q921H7	Gene names	Znf553, Zfp553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.