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Network neighborhood for query Sequence : HTRA1_MOUSE

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HTRA1_MOUSE
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HTRA1_HUMAN
θ value	0 (rank : 1)	NC score	0.990165 (rank : 2)
Query Neighborhood Hits	140	Target Neighborhood Hits	155	Shared Neighborhood Hits	121
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HTRA1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	140	Target Neighborhood Hits	140	Shared Neighborhood Hits	140
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

HTRA3_HUMAN
θ value	2.4321e-138 (rank : 3)	NC score	0.960360 (rank : 4)
Query Neighborhood Hits	140	Target Neighborhood Hits	152	Shared Neighborhood Hits	93
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
θ value	1.63136e-134 (rank : 4)	NC score	0.960934 (rank : 3)
Query Neighborhood Hits	140	Target Neighborhood Hits	156	Shared Neighborhood Hits	93
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HTRA4_HUMAN
θ value	1.29261e-131 (rank : 5)	NC score	0.947567 (rank : 5)
Query Neighborhood Hits	140	Target Neighborhood Hits	119	Shared Neighborhood Hits	73
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

HTRA2_HUMAN
θ value	1.03614e-88 (rank : 6)	NC score	0.871812 (rank : 7)
Query Neighborhood Hits	140	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HTRA2_MOUSE
θ value	1.03614e-88 (rank : 7)	NC score	0.873310 (rank : 6)
Query Neighborhood Hits	140	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

IBP7_HUMAN
θ value	2.43343e-21 (rank : 8)	NC score	0.533448 (rank : 8)
Query Neighborhood Hits	140	Target Neighborhood Hits	220	Shared Neighborhood Hits	50
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

KAZD1_HUMAN
θ value	5.07402e-19 (rank : 9)	NC score	0.469695 (rank : 10)
Query Neighborhood Hits	140	Target Neighborhood Hits	248	Shared Neighborhood Hits	58
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

IBP7_MOUSE
θ value	1.13037e-18 (rank : 10)	NC score	0.531797 (rank : 9)
Query Neighborhood Hits	140	Target Neighborhood Hits	230	Shared Neighborhood Hits	49
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

KAZD1_MOUSE
θ value	1.92812e-18 (rank : 11)	NC score	0.449320 (rank : 11)
Query Neighborhood Hits	140	Target Neighborhood Hits	281	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

ESM1_MOUSE
θ value	3.41135e-07 (rank : 12)	NC score	0.406793 (rank : 12)
Query Neighborhood Hits	140	Target Neighborhood Hits	107	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

IBP3_HUMAN
θ value	9.92553e-07 (rank : 13)	NC score	0.360498 (rank : 14)
Query Neighborhood Hits	140	Target Neighborhood Hits	67	Shared Neighborhood Hits	42
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

ESM1_HUMAN
θ value	1.69304e-06 (rank : 14)	NC score	0.382938 (rank : 13)
Query Neighborhood Hits	140	Target Neighborhood Hits	110	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

IBP2_HUMAN
θ value	1.69304e-06 (rank : 15)	NC score	0.339092 (rank : 15)
Query Neighborhood Hits	140	Target Neighborhood Hits	61	Shared Neighborhood Hits	43
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP1_MOUSE
θ value	2.21117e-06 (rank : 16)	NC score	0.339042 (rank : 16)
Query Neighborhood Hits	140	Target Neighborhood Hits	97	Shared Neighborhood Hits	48
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

CRIM1_HUMAN
θ value	8.40245e-06 (rank : 17)	NC score	0.193842 (rank : 39)
Query Neighborhood Hits	140	Target Neighborhood Hits	362	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

IBP3_MOUSE
θ value	8.40245e-06 (rank : 18)	NC score	0.310904 (rank : 20)
Query Neighborhood Hits	140	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP5_HUMAN
θ value	1.43324e-05 (rank : 19)	NC score	0.335645 (rank : 18)
Query Neighborhood Hits	140	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
θ value	1.43324e-05 (rank : 20)	NC score	0.336098 (rank : 17)
Query Neighborhood Hits	140	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP4_HUMAN
θ value	1.87187e-05 (rank : 21)	NC score	0.300563 (rank : 22)
Query Neighborhood Hits	140	Target Neighborhood Hits	52	Shared Neighborhood Hits	36
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_MOUSE
θ value	3.19293e-05 (rank : 22)	NC score	0.295479 (rank : 24)
Query Neighborhood Hits	140	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP2_MOUSE
θ value	5.44631e-05 (rank : 23)	NC score	0.327496 (rank : 19)
Query Neighborhood Hits	140	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

CYR61_HUMAN
θ value	9.29e-05 (rank : 24)	NC score	0.253219 (rank : 29)
Query Neighborhood Hits	140	Target Neighborhood Hits	159	Shared Neighborhood Hits	34
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	9.29e-05 (rank : 25)	NC score	0.253766 (rank : 27)
Query Neighborhood Hits	140	Target Neighborhood Hits	156	Shared Neighborhood Hits	35
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

PDZD1_MOUSE
θ value	0.000270298 (rank : 26)	NC score	0.161367 (rank : 44)
Query Neighborhood Hits	140	Target Neighborhood Hits	191	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

AGRIN_HUMAN
θ value	0.000461057 (rank : 27)	NC score	0.120997 (rank : 61)
Query Neighborhood Hits	140	Target Neighborhood Hits	582	Shared Neighborhood Hits	60
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

NOV_HUMAN
θ value	0.000461057 (rank : 28)	NC score	0.246927 (rank : 32)
Query Neighborhood Hits	140	Target Neighborhood Hits	128	Shared Neighborhood Hits	34
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

IBP1_HUMAN
θ value	0.00134147 (rank : 29)	NC score	0.298342 (rank : 23)
Query Neighborhood Hits	140	Target Neighborhood Hits	67	Shared Neighborhood Hits	46
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

PDZD1_HUMAN
θ value	0.00134147 (rank : 30)	NC score	0.159160 (rank : 46)
Query Neighborhood Hits	140	Target Neighborhood Hits	190	Shared Neighborhood Hits	53
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

NOV_MOUSE
θ value	0.00228821 (rank : 31)	NC score	0.230570 (rank : 33)
Query Neighborhood Hits	140	Target Neighborhood Hits	130	Shared Neighborhood Hits	33
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NHERF_MOUSE
θ value	0.00869519 (rank : 32)	NC score	0.137021 (rank : 56)
Query Neighborhood Hits	140	Target Neighborhood Hits	195	Shared Neighborhood Hits	48
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

CTGF_HUMAN
θ value	0.0113563 (rank : 33)	NC score	0.252472 (rank : 30)
Query Neighborhood Hits	140	Target Neighborhood Hits	128	Shared Neighborhood Hits	39
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

WISP2_HUMAN
θ value	0.0113563 (rank : 34)	NC score	0.258561 (rank : 26)
Query Neighborhood Hits	140	Target Neighborhood Hits	126	Shared Neighborhood Hits	35
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

CTGF_MOUSE
θ value	0.0193708 (rank : 35)	NC score	0.211000 (rank : 37)
Query Neighborhood Hits	140	Target Neighborhood Hits	124	Shared Neighborhood Hits	34
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

NHERF_HUMAN
θ value	0.0193708 (rank : 36)	NC score	0.140117 (rank : 54)
Query Neighborhood Hits	140	Target Neighborhood Hits	190	Shared Neighborhood Hits	50
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

FSTL3_HUMAN
θ value	0.0431538 (rank : 37)	NC score	0.168448 (rank : 41)
Query Neighborhood Hits	140	Target Neighborhood Hits	162	Shared Neighborhood Hits	41
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

KRA56_HUMAN
θ value	0.125558 (rank : 38)	NC score	0.047842 (rank : 136)
Query Neighborhood Hits	140	Target Neighborhood Hits	207	Shared Neighborhood Hits	15
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

RHPN1_HUMAN
θ value	0.163984 (rank : 39)	NC score	0.095710 (rank : 79)
Query Neighborhood Hits	140	Target Neighborhood Hits	158	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

TEFF2_MOUSE
θ value	0.163984 (rank : 40)	NC score	0.115987 (rank : 65)
Query Neighborhood Hits	140	Target Neighborhood Hits	214	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

FSTL5_HUMAN
θ value	0.21417 (rank : 41)	NC score	0.066350 (rank : 112)
Query Neighborhood Hits	140	Target Neighborhood Hits	347	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

IBP6_MOUSE
θ value	0.21417 (rank : 42)	NC score	0.206947 (rank : 38)
Query Neighborhood Hits	140	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

RHPN1_MOUSE
θ value	0.21417 (rank : 43)	NC score	0.094578 (rank : 80)
Query Neighborhood Hits	140	Target Neighborhood Hits	154	Shared Neighborhood Hits	43
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

WISP2_MOUSE
θ value	0.21417 (rank : 44)	NC score	0.222282 (rank : 34)
Query Neighborhood Hits	140	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

KRA53_HUMAN
θ value	0.279714 (rank : 45)	NC score	0.040288 (rank : 141)
Query Neighborhood Hits	140	Target Neighborhood Hits	331	Shared Neighborhood Hits	18
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

TEFF2_HUMAN
θ value	0.279714 (rank : 46)	NC score	0.112763 (rank : 68)
Query Neighborhood Hits	140	Target Neighborhood Hits	211	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

FSTL5_MOUSE
θ value	0.365318 (rank : 47)	NC score	0.064631 (rank : 113)
Query Neighborhood Hits	140	Target Neighborhood Hits	355	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

LCE1B_HUMAN
θ value	0.365318 (rank : 48)	NC score	0.253674 (rank : 28)
Query Neighborhood Hits	140	Target Neighborhood Hits	58	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.282716 (rank : 25)
Query Neighborhood Hits	140	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

WISP3_HUMAN
θ value	0.365318 (rank : 50)	NC score	0.220588 (rank : 35)
Query Neighborhood Hits	140	Target Neighborhood Hits	87	Shared Neighborhood Hits	31
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

FSTL3_MOUSE
θ value	0.47712 (rank : 51)	NC score	0.160083 (rank : 45)
Query Neighborhood Hits	140	Target Neighborhood Hits	152	Shared Neighborhood Hits	43
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.145881 (rank : 49)
Query Neighborhood Hits	140	Target Neighborhood Hits	129	Shared Neighborhood Hits	45
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	0.47712 (rank : 53)	NC score	0.145234 (rank : 50)
Query Neighborhood Hits	140	Target Neighborhood Hits	146	Shared Neighborhood Hits	47
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

NHRF2_HUMAN
θ value	0.47712 (rank : 54)	NC score	0.118720 (rank : 62)
Query Neighborhood Hits	140	Target Neighborhood Hits	197	Shared Neighborhood Hits	48
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

PDZ11_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.144783 (rank : 51)
Query Neighborhood Hits	140	Target Neighborhood Hits	160	Shared Neighborhood Hits	46
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	0.47712 (rank : 56)	NC score	0.143952 (rank : 52)
Query Neighborhood Hits	140	Target Neighborhood Hits	154	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZD3_MOUSE
θ value	0.47712 (rank : 57)	NC score	0.137537 (rank : 55)
Query Neighborhood Hits	140	Target Neighborhood Hits	171	Shared Neighborhood Hits	48
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

ZO3_MOUSE
θ value	0.47712 (rank : 58)	NC score	0.075090 (rank : 100)
Query Neighborhood Hits	140	Target Neighborhood Hits	224	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

FSTL4_MOUSE
θ value	0.62314 (rank : 59)	NC score	0.083659 (rank : 92)
Query Neighborhood Hits	140	Target Neighborhood Hits	333	Shared Neighborhood Hits	38
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

NHRF2_MOUSE
θ value	0.62314 (rank : 60)	NC score	0.113040 (rank : 67)
Query Neighborhood Hits	140	Target Neighborhood Hits	194	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

SMOC1_MOUSE
θ value	0.62314 (rank : 61)	NC score	0.117170 (rank : 64)
Query Neighborhood Hits	140	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

GRASP_HUMAN
θ value	0.813845 (rank : 62)	NC score	0.092316 (rank : 85)
Query Neighborhood Hits	140	Target Neighborhood Hits	147	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

MEGF6_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.031939 (rank : 142)
Query Neighborhood Hits	140	Target Neighborhood Hits	671	Shared Neighborhood Hits	53
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

WHRN_MOUSE
θ value	0.813845 (rank : 64)	NC score	0.094398 (rank : 81)
Query Neighborhood Hits	140	Target Neighborhood Hits	412	Shared Neighborhood Hits	50
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

ADM1B_MOUSE
θ value	1.06291 (rank : 65)	NC score	0.012002 (rank : 150)
Query Neighborhood Hits	140	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

FSTL4_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.068935 (rank : 105)
Query Neighborhood Hits	140	Target Neighborhood Hits	344	Shared Neighborhood Hits	33
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

IBP6_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.211900 (rank : 36)
Query Neighborhood Hits	140	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

LAP4_HUMAN
θ value	1.06291 (rank : 68)	NC score	0.055947 (rank : 127)
Query Neighborhood Hits	140	Target Neighborhood Hits	608	Shared Neighborhood Hits	50
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

ADA12_MOUSE
θ value	1.38821 (rank : 69)	NC score	0.011072 (rank : 153)
Query Neighborhood Hits	140	Target Neighborhood Hits	474	Shared Neighborhood Hits	15
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

LCE1E_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.303293 (rank : 21)
Query Neighborhood Hits	140	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE2B_HUMAN
θ value	1.38821 (rank : 71)	NC score	0.129317 (rank : 60)
Query Neighborhood Hits	140	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

PDZK4_MOUSE
θ value	1.38821 (rank : 72)	NC score	0.071449 (rank : 102)
Query Neighborhood Hits	140	Target Neighborhood Hits	165	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

SMOC1_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.108623 (rank : 71)
Query Neighborhood Hits	140	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

USH1C_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.093204 (rank : 84)
Query Neighborhood Hits	140	Target Neighborhood Hits	327	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.086862 (rank : 90)
Query Neighborhood Hits	140	Target Neighborhood Hits	557	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

WHRN_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.094110 (rank : 82)
Query Neighborhood Hits	140	Target Neighborhood Hits	325	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WISP1_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.165641 (rank : 43)
Query Neighborhood Hits	140	Target Neighborhood Hits	121	Shared Neighborhood Hits	26
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP1_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.176329 (rank : 40)
Query Neighborhood Hits	140	Target Neighborhood Hits	123	Shared Neighborhood Hits	31
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

CUBN_HUMAN
θ value	1.81305 (rank : 79)	NC score	0.011228 (rank : 152)
Query Neighborhood Hits	140	Target Neighborhood Hits	482	Shared Neighborhood Hits	21
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

FSTL1_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.108430 (rank : 72)
Query Neighborhood Hits	140	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
θ value	1.81305 (rank : 81)	NC score	0.106749 (rank : 73)
Query Neighborhood Hits	140	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

GRASP_MOUSE
θ value	1.81305 (rank : 82)	NC score	0.088039 (rank : 89)
Query Neighborhood Hits	140	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

MPDZ_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.068323 (rank : 107)
Query Neighborhood Hits	140	Target Neighborhood Hits	261	Shared Neighborhood Hits	48
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

ZO1_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.062366 (rank : 119)
Query Neighborhood Hits	140	Target Neighborhood Hits	474	Shared Neighborhood Hits	46
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.061851 (rank : 121)
Query Neighborhood Hits	140	Target Neighborhood Hits	453	Shared Neighborhood Hits	46
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ITB2_MOUSE
θ value	2.36792 (rank : 86)	NC score	0.016272 (rank : 146)
Query Neighborhood Hits	140	Target Neighborhood Hits	326	Shared Neighborhood Hits	20
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KR511_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.041971 (rank : 140)
Query Neighborhood Hits	140	Target Neighborhood Hits	231	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

MPDZ_MOUSE
θ value	2.36792 (rank : 88)	NC score	0.072359 (rank : 101)
Query Neighborhood Hits	140	Target Neighborhood Hits	298	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PDZK4_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.068947 (rank : 104)
Query Neighborhood Hits	140	Target Neighborhood Hits	165	Shared Neighborhood Hits	39
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

TICN1_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.093344 (rank : 83)
Query Neighborhood Hits	140	Target Neighborhood Hits	70	Shared Neighborhood Hits	40
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

ZO3_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.060582 (rank : 122)
Query Neighborhood Hits	140	Target Neighborhood Hits	219	Shared Neighborhood Hits	45
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

IPK1_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.133707 (rank : 58)
Query Neighborhood Hits	140	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

ISK3_MOUSE
θ value	3.0926 (rank : 93)	NC score	0.146196 (rank : 48)
Query Neighborhood Hits	140	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

LIN7A_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.068124 (rank : 110)
Query Neighborhood Hits	140	Target Neighborhood Hits	193	Shared Neighborhood Hits	46
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

LIN7A_MOUSE
θ value	3.0926 (rank : 95)	NC score	0.068240 (rank : 108)
Query Neighborhood Hits	140	Target Neighborhood Hits	193	Shared Neighborhood Hits	46
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

MAGI1_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.055468 (rank : 129)
Query Neighborhood Hits	140	Target Neighborhood Hits	388	Shared Neighborhood Hits	45
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
θ value	3.0926 (rank : 97)	NC score	0.055808 (rank : 128)
Query Neighborhood Hits	140	Target Neighborhood Hits	403	Shared Neighborhood Hits	45
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

PDZD3_HUMAN
θ value	3.0926 (rank : 98)	NC score	0.131097 (rank : 59)
Query Neighborhood Hits	140	Target Neighborhood Hits	180	Shared Neighborhood Hits	47
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PSCBP_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.076086 (rank : 98)
Query Neighborhood Hits	140	Target Neighborhood Hits	123	Shared Neighborhood Hits	45
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

PZRN4_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.075669 (rank : 99)
Query Neighborhood Hits	140	Target Neighborhood Hits	438	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TENX_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.023726 (rank : 145)
Query Neighborhood Hits	140	Target Neighborhood Hits	789	Shared Neighborhood Hits	35
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TICN1_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.102837 (rank : 74)
Query Neighborhood Hits	140	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

ATX2_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.012187 (rank : 149)
Query Neighborhood Hits	140	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

LCE1D_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.252378 (rank : 31)
Query Neighborhood Hits	140	Target Neighborhood Hits	44	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE2A_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.089017 (rank : 87)
Query Neighborhood Hits	140	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

SMOC2_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.101106 (rank : 76)
Query Neighborhood Hits	140	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

TENR_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.009602 (rank : 155)
Query Neighborhood Hits	140	Target Neighborhood Hits	526	Shared Neighborhood Hits	16
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TNR14_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.026027 (rank : 143)
Query Neighborhood Hits	140	Target Neighborhood Hits	149	Shared Neighborhood Hits	10
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

ZDHC3_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.006817 (rank : 156)
Query Neighborhood Hits	140	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R173, Q6EMK3	Gene names	Zdhhc3, Godz, Gramp1
Domain Architecture
Description	Palmitoyltransferase ZDHHC3 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 3) (DHHC-3) (Golgi-specific DHHC zinc finger protein) (GABA-A receptor-associated membrane protein 1).

ISK5_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.084972 (rank : 91)
Query Neighborhood Hits	140	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

LAP4_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.050228 (rank : 133)
Query Neighborhood Hits	140	Target Neighborhood Hits	590	Shared Neighborhood Hits	50
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LCE2C_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.112606 (rank : 69)
Query Neighborhood Hits	140	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LIN7B_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.069843 (rank : 103)
Query Neighborhood Hits	140	Target Neighborhood Hits	200	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

LIN7B_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.068541 (rank : 106)
Query Neighborhood Hits	140	Target Neighborhood Hits	200	Shared Neighborhood Hits	47
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

SMOC2_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.097749 (rank : 77)
Query Neighborhood Hits	140	Target Neighborhood Hits	88	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SPR2B_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.045491 (rank : 137)
Query Neighborhood Hits	140	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

CREL1_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.011342 (rank : 151)
Query Neighborhood Hits	140	Target Neighborhood Hits	524	Shared Neighborhood Hits	17
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

GOPC_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.062077 (rank : 120)
Query Neighborhood Hits	140	Target Neighborhood Hits	377	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.063085 (rank : 117)
Query Neighborhood Hits	140	Target Neighborhood Hits	323	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

ISK4_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.063506 (rank : 116)
Query Neighborhood Hits	140	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

ISK6_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.101765 (rank : 75)
Query Neighborhood Hits	140	Target Neighborhood Hits	37	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

JAG2_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.013515 (rank : 148)
Query Neighborhood Hits	140	Target Neighborhood Hits	504	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LCE2D_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.136981 (rank : 57)
Query Neighborhood Hits	140	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

PSMD9_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.042199 (rank : 139)
Query Neighborhood Hits	140	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CR00, Q3TG66	Gene names	Psmd9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

RECK_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.081624 (rank : 93)
Query Neighborhood Hits	140	Target Neighborhood Hits	189	Shared Neighborhood Hits	41
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.078585 (rank : 97)
Query Neighborhood Hits	140	Target Neighborhood Hits	158	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TICN3_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.097009 (rank : 78)
Query Neighborhood Hits	140	Target Neighborhood Hits	83	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

ATX2_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.010988 (rank : 154)
Query Neighborhood Hits	140	Target Neighborhood Hits	375	Shared Neighborhood Hits	4
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

KR122_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.026016 (rank : 144)
Query Neighborhood Hits	140	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

LCE4A_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.118671 (rank : 63)
Query Neighborhood Hits	140	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.142546 (rank : 53)
Query Neighborhood Hits	140	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LIN7C_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.064483 (rank : 114)
Query Neighborhood Hits	140	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.064483 (rank : 115)
Query Neighborhood Hits	140	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

PSCBP_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.062564 (rank : 118)
Query Neighborhood Hits	140	Target Neighborhood Hits	118	Shared Neighborhood Hits	41
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

PSMD9_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.042417 (rank : 138)
Query Neighborhood Hits	140	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	O00233, Q9BQ42	Gene names	PSMD9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

PZRN3_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.067591 (rank : 111)
Query Neighborhood Hits	140	Target Neighborhood Hits	461	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.068194 (rank : 109)
Query Neighborhood Hits	140	Target Neighborhood Hits	447	Shared Neighborhood Hits	44
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

SO5A1_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.016153 (rank : 147)
Query Neighborhood Hits	140	Target Neighborhood Hits	57	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

TICN2_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.110102 (rank : 70)
Query Neighborhood Hits	140	Target Neighborhood Hits	68	Shared Neighborhood Hits	42
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.113661 (rank : 66)
Query Neighborhood Hits	140	Target Neighborhood Hits	69	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

ARHGB_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.050010 (rank : 135)
Query Neighborhood Hits	140	Target Neighborhood Hits	375	Shared Neighborhood Hits	46
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

GRIP2_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.057512 (rank : 124)
Query Neighborhood Hits	140	Target Neighborhood Hits	256	Shared Neighborhood Hits	49
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

HG2A_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.056348 (rank : 125)
Query Neighborhood Hits	140	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

INADL_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.053613 (rank : 130)
Query Neighborhood Hits	140	Target Neighborhood Hits	290	Shared Neighborhood Hits	47
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

IPK2_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.050998 (rank : 132)
Query Neighborhood Hits	140	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

ISK6_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.088432 (rank : 88)
Query Neighborhood Hits	140	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

LCE1A_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.167108 (rank : 42)
Query Neighborhood Hits	140	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1F_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.150459 (rank : 47)
Query Neighborhood Hits	140	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

PDZD7_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.080112 (rank : 96)
Query Neighborhood Hits	140	Target Neighborhood Hits	181	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

RPGF6_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.051050 (rank : 131)
Query Neighborhood Hits	140	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SDCB1_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.058333 (rank : 123)
Query Neighborhood Hits	140	Target Neighborhood Hits	150	Shared Neighborhood Hits	46
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

SDCB1_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.056341 (rank : 126)
Query Neighborhood Hits	140	Target Neighborhood Hits	144	Shared Neighborhood Hits	46
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

SYJ2B_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.050124 (rank : 134)
Query Neighborhood Hits	140	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

TICN3_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.089309 (rank : 86)
Query Neighborhood Hits	140	Target Neighborhood Hits	82	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TX1B3_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.081357 (rank : 94)
Query Neighborhood Hits	140	Target Neighborhood Hits	161	Shared Neighborhood Hits	47
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.080853 (rank : 95)
Query Neighborhood Hits	140	Target Neighborhood Hits	158	Shared Neighborhood Hits	47
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

Hits sorted by NC score

HTRA1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	140	Target Neighborhood Hits	140	Shared Neighborhood Hits	140
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

HTRA1_HUMAN
NC score	0.990165 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	140	Target Neighborhood Hits	155	Shared Neighborhood Hits	121
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HTRA3_MOUSE
NC score	0.960934 (rank : 3)	θ value	1.63136e-134 (rank : 4)
Query Neighborhood Hits	140	Target Neighborhood Hits	156	Shared Neighborhood Hits	93
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HTRA3_HUMAN
NC score	0.960360 (rank : 4)	θ value	2.4321e-138 (rank : 3)
Query Neighborhood Hits	140	Target Neighborhood Hits	152	Shared Neighborhood Hits	93
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA4_HUMAN
NC score	0.947567 (rank : 5)	θ value	1.29261e-131 (rank : 5)
Query Neighborhood Hits	140	Target Neighborhood Hits	119	Shared Neighborhood Hits	73
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

HTRA2_MOUSE
NC score	0.873310 (rank : 6)	θ value	1.03614e-88 (rank : 7)
Query Neighborhood Hits	140	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HTRA2_HUMAN
NC score	0.871812 (rank : 7)	θ value	1.03614e-88 (rank : 6)
Query Neighborhood Hits	140	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

IBP7_HUMAN
NC score	0.533448 (rank : 8)	θ value	2.43343e-21 (rank : 8)
Query Neighborhood Hits	140	Target Neighborhood Hits	220	Shared Neighborhood Hits	50
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IBP7_MOUSE
NC score	0.531797 (rank : 9)	θ value	1.13037e-18 (rank : 10)
Query Neighborhood Hits	140	Target Neighborhood Hits	230	Shared Neighborhood Hits	49
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

KAZD1_HUMAN
NC score	0.469695 (rank : 10)	θ value	5.07402e-19 (rank : 9)
Query Neighborhood Hits	140	Target Neighborhood Hits	248	Shared Neighborhood Hits	58
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
NC score	0.449320 (rank : 11)	θ value	1.92812e-18 (rank : 11)
Query Neighborhood Hits	140	Target Neighborhood Hits	281	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

ESM1_MOUSE
NC score	0.406793 (rank : 12)	θ value	3.41135e-07 (rank : 12)
Query Neighborhood Hits	140	Target Neighborhood Hits	107	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_HUMAN
NC score	0.382938 (rank : 13)	θ value	1.69304e-06 (rank : 14)
Query Neighborhood Hits	140	Target Neighborhood Hits	110	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

IBP3_HUMAN
NC score	0.360498 (rank : 14)	θ value	9.92553e-07 (rank : 13)
Query Neighborhood Hits	140	Target Neighborhood Hits	67	Shared Neighborhood Hits	42
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP2_HUMAN
NC score	0.339092 (rank : 15)	θ value	1.69304e-06 (rank : 15)
Query Neighborhood Hits	140	Target Neighborhood Hits	61	Shared Neighborhood Hits	43
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP1_MOUSE
NC score	0.339042 (rank : 16)	θ value	2.21117e-06 (rank : 16)
Query Neighborhood Hits	140	Target Neighborhood Hits	97	Shared Neighborhood Hits	48
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP5_MOUSE
NC score	0.336098 (rank : 17)	θ value	1.43324e-05 (rank : 20)
Query Neighborhood Hits	140	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_HUMAN
NC score	0.335645 (rank : 18)	θ value	1.43324e-05 (rank : 19)
Query Neighborhood Hits	140	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP2_MOUSE
NC score	0.327496 (rank : 19)	θ value	5.44631e-05 (rank : 23)
Query Neighborhood Hits	140	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP3_MOUSE
NC score	0.310904 (rank : 20)	θ value	8.40245e-06 (rank : 18)
Query Neighborhood Hits	140	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

LCE1E_HUMAN
NC score	0.303293 (rank : 21)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	140	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

IBP4_HUMAN
NC score	0.300563 (rank : 22)	θ value	1.87187e-05 (rank : 21)
Query Neighborhood Hits	140	Target Neighborhood Hits	52	Shared Neighborhood Hits	36
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP1_HUMAN
NC score	0.298342 (rank : 23)	θ value	0.00134147 (rank : 29)
Query Neighborhood Hits	140	Target Neighborhood Hits	67	Shared Neighborhood Hits	46
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP4_MOUSE
NC score	0.295479 (rank : 24)	θ value	3.19293e-05 (rank : 22)
Query Neighborhood Hits	140	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

LCE1C_HUMAN
NC score	0.282716 (rank : 25)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	140	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

WISP2_HUMAN
NC score	0.258561 (rank : 26)	θ value	0.0113563 (rank : 34)
Query Neighborhood Hits	140	Target Neighborhood Hits	126	Shared Neighborhood Hits	35
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

CYR61_MOUSE
NC score	0.253766 (rank : 27)	θ value	9.29e-05 (rank : 25)
Query Neighborhood Hits	140	Target Neighborhood Hits	156	Shared Neighborhood Hits	35
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

LCE1B_HUMAN
NC score	0.253674 (rank : 28)	θ value	0.365318 (rank : 48)
Query Neighborhood Hits	140	Target Neighborhood Hits	58	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

CYR61_HUMAN
NC score	0.253219 (rank : 29)	θ value	9.29e-05 (rank : 24)
Query Neighborhood Hits	140	Target Neighborhood Hits	159	Shared Neighborhood Hits	34
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CTGF_HUMAN
NC score	0.252472 (rank : 30)	θ value	0.0113563 (rank : 33)
Query Neighborhood Hits	140	Target Neighborhood Hits	128	Shared Neighborhood Hits	39
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

LCE1D_HUMAN
NC score	0.252378 (rank : 31)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	140	Target Neighborhood Hits	44	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

NOV_HUMAN
NC score	0.246927 (rank : 32)	θ value	0.000461057 (rank : 28)
Query Neighborhood Hits	140	Target Neighborhood Hits	128	Shared Neighborhood Hits	34
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOV_MOUSE
NC score	0.230570 (rank : 33)	θ value	0.00228821 (rank : 31)
Query Neighborhood Hits	140	Target Neighborhood Hits	130	Shared Neighborhood Hits	33
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

WISP2_MOUSE
NC score	0.222282 (rank : 34)	θ value	0.21417 (rank : 44)
Query Neighborhood Hits	140	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

WISP3_HUMAN
NC score	0.220588 (rank : 35)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	140	Target Neighborhood Hits	87	Shared Neighborhood Hits	31
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

IBP6_HUMAN
NC score	0.211900 (rank : 36)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	140	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

CTGF_MOUSE
NC score	0.211000 (rank : 37)	θ value	0.0193708 (rank : 35)
Query Neighborhood Hits	140	Target Neighborhood Hits	124	Shared Neighborhood Hits	34
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

IBP6_MOUSE
NC score	0.206947 (rank : 38)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	140	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

CRIM1_HUMAN
NC score	0.193842 (rank : 39)	θ value	8.40245e-06 (rank : 17)
Query Neighborhood Hits	140	Target Neighborhood Hits	362	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

WISP1_MOUSE
NC score	0.176329 (rank : 40)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	140	Target Neighborhood Hits	123	Shared Neighborhood Hits	31
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

FSTL3_HUMAN
NC score	0.168448 (rank : 41)	θ value	0.0431538 (rank : 37)
Query Neighborhood Hits	140	Target Neighborhood Hits	162	Shared Neighborhood Hits	41
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

LCE1A_HUMAN
NC score	0.167108 (rank : 42)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	140	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

WISP1_HUMAN
NC score	0.165641 (rank : 43)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	140	Target Neighborhood Hits	121	Shared Neighborhood Hits	26
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

PDZD1_MOUSE
NC score	0.161367 (rank : 44)	θ value	0.000270298 (rank : 26)
Query Neighborhood Hits	140	Target Neighborhood Hits	191	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

FSTL3_MOUSE
NC score	0.160083 (rank : 45)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	140	Target Neighborhood Hits	152	Shared Neighborhood Hits	43
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

PDZD1_HUMAN
NC score	0.159160 (rank : 46)	θ value	0.00134147 (rank : 30)
Query Neighborhood Hits	140	Target Neighborhood Hits	190	Shared Neighborhood Hits	53
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

LCE1F_HUMAN
NC score	0.150459 (rank : 47)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	140	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

ISK3_MOUSE
NC score	0.146196 (rank : 48)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	140	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

FST_HUMAN
NC score	0.145881 (rank : 49)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	140	Target Neighborhood Hits	129	Shared Neighborhood Hits	45
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
NC score	0.145234 (rank : 50)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	140	Target Neighborhood Hits	146	Shared Neighborhood Hits	47
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

PDZ11_HUMAN
NC score	0.144783 (rank : 51)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	140	Target Neighborhood Hits	160	Shared Neighborhood Hits	46
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
NC score	0.143952 (rank : 52)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	140	Target Neighborhood Hits	154	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

LCE5A_HUMAN
NC score	0.142546 (rank : 53)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	140	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

NHERF_HUMAN
NC score	0.140117 (rank : 54)	θ value	0.0193708 (rank : 36)
Query Neighborhood Hits	140	Target Neighborhood Hits	190	Shared Neighborhood Hits	50
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PDZD3_MOUSE
NC score	0.137537 (rank : 55)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	140	Target Neighborhood Hits	171	Shared Neighborhood Hits	48
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

NHERF_MOUSE
NC score	0.137021 (rank : 56)	θ value	0.00869519 (rank : 32)
Query Neighborhood Hits	140	Target Neighborhood Hits	195	Shared Neighborhood Hits	48
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

LCE2D_HUMAN
NC score	0.136981 (rank : 57)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	140	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

IPK1_HUMAN
NC score	0.133707 (rank : 58)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	140	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

PDZD3_HUMAN
NC score	0.131097 (rank : 59)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	140	Target Neighborhood Hits	180	Shared Neighborhood Hits	47
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

LCE2B_HUMAN
NC score	0.129317 (rank : 60)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	140	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

AGRIN_HUMAN
NC score	0.120997 (rank : 61)	θ value	0.000461057 (rank : 27)
Query Neighborhood Hits	140	Target Neighborhood Hits	582	Shared Neighborhood Hits	60
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

NHRF2_HUMAN
NC score	0.118720 (rank : 62)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	140	Target Neighborhood Hits	197	Shared Neighborhood Hits	48
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

LCE4A_HUMAN
NC score	0.118671 (rank : 63)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	140	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

SMOC1_MOUSE
NC score	0.117170 (rank : 64)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	140	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

TEFF2_MOUSE
NC score	0.115987 (rank : 65)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	140	Target Neighborhood Hits	214	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TICN2_MOUSE
NC score	0.113661 (rank : 66)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	140	Target Neighborhood Hits	69	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

NHRF2_MOUSE
NC score	0.113040 (rank : 67)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	140	Target Neighborhood Hits	194	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

TEFF2_HUMAN
NC score	0.112763 (rank : 68)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	140	Target Neighborhood Hits	211	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

LCE2C_HUMAN
NC score	0.112606 (rank : 69)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	140	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

TICN2_HUMAN
NC score	0.110102 (rank : 70)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	140	Target Neighborhood Hits	68	Shared Neighborhood Hits	42
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

SMOC1_HUMAN
NC score	0.108623 (rank : 71)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	140	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

FSTL1_HUMAN
NC score	0.108430 (rank : 72)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	140	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
NC score	0.106749 (rank : 73)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	140	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

TICN1_MOUSE
NC score	0.102837 (rank : 74)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	140	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

ISK6_MOUSE
NC score	0.101765 (rank : 75)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	140	Target Neighborhood Hits	37	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

SMOC2_MOUSE
NC score	0.101106 (rank : 76)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	140	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

SMOC2_HUMAN
NC score	0.097749 (rank : 77)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	140	Target Neighborhood Hits	88	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

TICN3_MOUSE
NC score	0.097009 (rank : 78)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	140	Target Neighborhood Hits	83	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

RHPN1_HUMAN
NC score	0.095710 (rank : 79)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	140	Target Neighborhood Hits	158	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TCX5, Q8TAV1	Gene names	RHPN1
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

RHPN1_MOUSE
NC score	0.094578 (rank : 80)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	140	Target Neighborhood Hits	154	Shared Neighborhood Hits	43
SwissProt Accessions	Q61085	Gene names	Rhpn1, Grbp
Domain Architecture
Description	Rhophilin-1 (GTP-Rho-binding protein 1).

WHRN_MOUSE
NC score	0.094398 (rank : 81)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	140	Target Neighborhood Hits	412	Shared Neighborhood Hits	50
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

WHRN_HUMAN
NC score	0.094110 (rank : 82)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	140	Target Neighborhood Hits	325	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

TICN1_HUMAN
NC score	0.093344 (rank : 83)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	140	Target Neighborhood Hits	70	Shared Neighborhood Hits	40
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

USH1C_HUMAN
NC score	0.093204 (rank : 84)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	140	Target Neighborhood Hits	327	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

GRASP_HUMAN
NC score	0.092316 (rank : 85)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	140	Target Neighborhood Hits	147	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z6J2, Q6PIF8, Q7Z741	Gene names	GRASP
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

TICN3_HUMAN
NC score	0.089309 (rank : 86)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	140	Target Neighborhood Hits	82	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

LCE2A_HUMAN
NC score	0.089017 (rank : 87)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	140	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

ISK6_HUMAN
NC score	0.088432 (rank : 88)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	140	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

GRASP_MOUSE
NC score	0.088039 (rank : 89)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	140	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JJA9, Q9JKL0	Gene names	Grasp
Domain Architecture	No domain graphic available
Description	General receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein).

USH1C_MOUSE
NC score	0.086862 (rank : 90)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	140	Target Neighborhood Hits	557	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

ISK5_HUMAN
NC score	0.084972 (rank : 91)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	140	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

FSTL4_MOUSE
NC score	0.083659 (rank : 92)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	140	Target Neighborhood Hits	333	Shared Neighborhood Hits	38
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

RECK_HUMAN
NC score	0.081624 (rank : 93)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	140	Target Neighborhood Hits	189	Shared Neighborhood Hits	41
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

TX1B3_HUMAN
NC score	0.081357 (rank : 94)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	140	Target Neighborhood Hits	161	Shared Neighborhood Hits	47
SwissProt Accessions	O14907, Q7LCQ4	Gene names	TAX1BP3, TIP1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).

TX1B3_MOUSE
NC score	0.080853 (rank : 95)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	140	Target Neighborhood Hits	158	Shared Neighborhood Hits	47
SwissProt Accessions	Q9DBG9	Gene names	Tax1bp3
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).

PDZD7_HUMAN
NC score	0.080112 (rank : 96)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	140	Target Neighborhood Hits	181	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H5P4, Q8N321	Gene names	PDZD7, PDZK7
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 7.

RECK_MOUSE
NC score	0.078585 (rank : 97)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	140	Target Neighborhood Hits	158	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

PSCBP_HUMAN
NC score	0.076086 (rank : 98)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	140	Target Neighborhood Hits	123	Shared Neighborhood Hits	45
SwissProt Accessions	O60759, Q15630, Q8NE32	Gene names	PSCDBP, CYTIP
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (CYBR) (Cytohesin binder and regulator) (Cytohesin-interacting protein).

PZRN4_HUMAN
NC score	0.075669 (rank : 99)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	140	Target Neighborhood Hits	438	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

ZO3_MOUSE
NC score	0.075090 (rank : 100)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	140	Target Neighborhood Hits	224	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

MPDZ_MOUSE
NC score	0.072359 (rank : 101)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	140	Target Neighborhood Hits	298	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PDZK4_MOUSE
NC score	0.071449 (rank : 102)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	140	Target Neighborhood Hits	165	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

LIN7B_HUMAN
NC score	0.069843 (rank : 103)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	140	Target Neighborhood Hits	200	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HAP6	Gene names	LIN7B, MALS2, VELI2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein) (hVeli2).

PDZK4_HUMAN
NC score	0.068947 (rank : 104)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	140	Target Neighborhood Hits	165	Shared Neighborhood Hits	39
SwissProt Accessions	Q76G19, Q8NB75, Q9BUH9, Q9P284	Gene names	PDZK4, KIAA1444, PDZRN4L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

FSTL4_HUMAN
NC score	0.068935 (rank : 105)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	140	Target Neighborhood Hits	344	Shared Neighborhood Hits	33
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

LIN7B_MOUSE
NC score	0.068541 (rank : 106)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	140	Target Neighborhood Hits	200	Shared Neighborhood Hits	47
SwissProt Accessions	O88951	Gene names	Lin7b, Mals2, Veli2
Domain Architecture	No domain graphic available
Description	Lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2 protein).

MPDZ_HUMAN
NC score	0.068323 (rank : 107)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	140	Target Neighborhood Hits	261	Shared Neighborhood Hits	48
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

LIN7A_MOUSE
NC score	0.068240 (rank : 108)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	140	Target Neighborhood Hits	193	Shared Neighborhood Hits	46
SwissProt Accessions	Q8JZS0	Gene names	Lin7a, Mals1, Veli1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein).

PZRN3_MOUSE
NC score	0.068194 (rank : 109)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	140	Target Neighborhood Hits	447	Shared Neighborhood Hits	44
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

LIN7A_HUMAN
NC score	0.068124 (rank : 110)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	140	Target Neighborhood Hits	193	Shared Neighborhood Hits	46
SwissProt Accessions	O14910, Q6LES3, Q7LDS4	Gene names	LIN7A, MALS1, VELI1
Domain Architecture	No domain graphic available
Description	Lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1 protein) (Tax interaction protein 33) (TIP-33).

PZRN3_HUMAN
NC score	0.067591 (rank : 111)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	140	Target Neighborhood Hits	461	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

FSTL5_HUMAN
NC score	0.066350 (rank : 112)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	140	Target Neighborhood Hits	347	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
NC score	0.064631 (rank : 113)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	140	Target Neighborhood Hits	355	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

LIN7C_HUMAN
NC score	0.064483 (rank : 114)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	140	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.064483 (rank : 115)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	140	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

ISK4_HUMAN
NC score	0.063506 (rank : 116)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	140	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

GOPC_MOUSE
NC score	0.063085 (rank : 117)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	140	Target Neighborhood Hits	323	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

PSCBP_MOUSE
NC score	0.062564 (rank : 118)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	140	Target Neighborhood Hits	118	Shared Neighborhood Hits	41
SwissProt Accessions	Q91VY6, Q3TZH1, Q8R4T4, Q9QZA9	Gene names	Pscdbp
Domain Architecture	No domain graphic available
Description	Pleckstrin homology Sec7 and coiled-coil domains-binding protein (Cytohesin-binding protein HE) (Cbp).

ZO1_HUMAN
NC score	0.062366 (rank : 119)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	140	Target Neighborhood Hits	474	Shared Neighborhood Hits	46
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

GOPC_HUMAN
NC score	0.062077 (rank : 120)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	140	Target Neighborhood Hits	377	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

ZO1_MOUSE
NC score	0.061851 (rank : 121)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	140	Target Neighborhood Hits	453	Shared Neighborhood Hits	46
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO3_HUMAN
NC score	0.060582 (rank : 122)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	140	Target Neighborhood Hits	219	Shared Neighborhood Hits	45
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

SDCB1_HUMAN
NC score	0.058333 (rank : 123)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	140	Target Neighborhood Hits	150	Shared Neighborhood Hits	46
SwissProt Accessions	O00560, O00173, O43391	Gene names	SDCBP, MDA9, SYCL
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).

GRIP2_HUMAN
NC score	0.057512 (rank : 124)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	140	Target Neighborhood Hits	256	Shared Neighborhood Hits	49
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

HG2A_MOUSE
NC score	0.056348 (rank : 125)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	140	Target Neighborhood Hits	36	Shared Neighborhood Hits	21
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

SDCB1_MOUSE
NC score	0.056341 (rank : 126)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	140	Target Neighborhood Hits	144	Shared Neighborhood Hits	46
SwissProt Accessions	O08992, Q544P5	Gene names	Sdcbp
Domain Architecture
Description	Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).

LAP4_HUMAN
NC score	0.055947 (rank : 127)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	140	Target Neighborhood Hits	608	Shared Neighborhood Hits	50
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MAGI1_MOUSE
NC score	0.055808 (rank : 128)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	140	Target Neighborhood Hits	403	Shared Neighborhood Hits	45
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAGI1_HUMAN
NC score	0.055468 (rank : 129)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	140	Target Neighborhood Hits	388	Shared Neighborhood Hits	45
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

INADL_MOUSE
NC score	0.053613 (rank : 130)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	140	Target Neighborhood Hits	290	Shared Neighborhood Hits	47
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

RPGF6_HUMAN
NC score	0.051050 (rank : 131)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	140	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

IPK2_HUMAN
NC score	0.050998 (rank : 132)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	140	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

LAP4_MOUSE
NC score	0.050228 (rank : 133)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	140	Target Neighborhood Hits	590	Shared Neighborhood Hits	50
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

SYJ2B_HUMAN
NC score	0.050124 (rank : 134)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	140	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

ARHGB_HUMAN
NC score	0.050010 (rank : 135)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	140	Target Neighborhood Hits	375	Shared Neighborhood Hits	46
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

KRA56_HUMAN
NC score	0.047842 (rank : 136)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	140	Target Neighborhood Hits	207	Shared Neighborhood Hits	15
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

SPR2B_MOUSE
NC score	0.045491 (rank : 137)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	140	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

PSMD9_HUMAN
NC score	0.042417 (rank : 138)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	140	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	O00233, Q9BQ42	Gene names	PSMD9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

PSMD9_MOUSE
NC score	0.042199 (rank : 139)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	140	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CR00, Q3TG66	Gene names	Psmd9
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27).

KR511_HUMAN
NC score	0.041971 (rank : 140)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	140	Target Neighborhood Hits	231	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA53_HUMAN
NC score	0.040288 (rank : 141)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	140	Target Neighborhood Hits	331	Shared Neighborhood Hits	18
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

MEGF6_HUMAN
NC score	0.031939 (rank : 142)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	140	Target Neighborhood Hits	671	Shared Neighborhood Hits	53
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TNR14_HUMAN
NC score	0.026027 (rank : 143)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	140	Target Neighborhood Hits	149	Shared Neighborhood Hits	10
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

KR122_HUMAN
NC score	0.026016 (rank : 144)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	140	Target Neighborhood Hits	97	Shared Neighborhood Hits	11
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

TENX_HUMAN
NC score	0.023726 (rank : 145)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	140	Target Neighborhood Hits	789	Shared Neighborhood Hits	35
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

ITB2_MOUSE
NC score	0.016272 (rank : 146)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	140	Target Neighborhood Hits	326	Shared Neighborhood Hits	20
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

SO5A1_HUMAN
NC score	0.016153 (rank : 147)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	140	Target Neighborhood Hits	57	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

JAG2_MOUSE
NC score	0.013515 (rank : 148)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	140	Target Neighborhood Hits	504	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

ATX2_MOUSE
NC score	0.012187 (rank : 149)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	140	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

ADM1B_MOUSE
NC score	0.012002 (rank : 150)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	140	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

CREL1_MOUSE
NC score	0.011342 (rank : 151)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	140	Target Neighborhood Hits	524	Shared Neighborhood Hits	17
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CUBN_HUMAN
NC score	0.011228 (rank : 152)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	140	Target Neighborhood Hits	482	Shared Neighborhood Hits	21
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

ADA12_MOUSE
NC score	0.011072 (rank : 153)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	140	Target Neighborhood Hits	474	Shared Neighborhood Hits	15
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ATX2_HUMAN
NC score	0.010988 (rank : 154)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	140	Target Neighborhood Hits	375	Shared Neighborhood Hits	4
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

TENR_HUMAN
NC score	0.009602 (rank : 155)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	140	Target Neighborhood Hits	526	Shared Neighborhood Hits	16
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ZDHC3_MOUSE
NC score	0.006817 (rank : 156)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	140	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R173, Q6EMK3	Gene names	Zdhhc3, Godz, Gramp1
Domain Architecture
Description	Palmitoyltransferase ZDHHC3 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 3) (DHHC-3) (Golgi-specific DHHC zinc finger protein) (GABA-A receptor-associated membrane protein 1).