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Network neighborhood for query Sequence : FSTL1_MOUSE

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FSTL1_MOUSE
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FSTL1_MOUSE
θ value	1.84073e-178 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	74
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FSTL1_HUMAN
θ value	1.08415e-162 (rank : 2)	NC score	0.998705 (rank : 2)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	67
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL4_HUMAN
θ value	2.5182e-18 (rank : 3)	NC score	0.432534 (rank : 7)
Query Neighborhood Hits	74	Target Neighborhood Hits	344	Shared Neighborhood Hits	41
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL5_HUMAN
θ value	4.29542e-18 (rank : 4)	NC score	0.419550 (rank : 9)
Query Neighborhood Hits	74	Target Neighborhood Hits	347	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
θ value	2.13179e-17 (rank : 5)	NC score	0.415709 (rank : 12)
Query Neighborhood Hits	74	Target Neighborhood Hits	355	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

FSTL4_MOUSE
θ value	6.85773e-16 (rank : 6)	NC score	0.429704 (rank : 8)
Query Neighborhood Hits	74	Target Neighborhood Hits	333	Shared Neighborhood Hits	40
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FST_HUMAN
θ value	9.26847e-13 (rank : 7)	NC score	0.603605 (rank : 3)
Query Neighborhood Hits	74	Target Neighborhood Hits	129	Shared Neighborhood Hits	51
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	1.2105e-12 (rank : 8)	NC score	0.602572 (rank : 4)
Query Neighborhood Hits	74	Target Neighborhood Hits	146	Shared Neighborhood Hits	52
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

AGRIN_HUMAN
θ value	2.13673e-09 (rank : 9)	NC score	0.274385 (rank : 29)
Query Neighborhood Hits	74	Target Neighborhood Hits	582	Shared Neighborhood Hits	60
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

FSTL3_MOUSE
θ value	1.53129e-07 (rank : 10)	NC score	0.540986 (rank : 6)
Query Neighborhood Hits	74	Target Neighborhood Hits	152	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_HUMAN
θ value	1.99992e-07 (rank : 11)	NC score	0.550021 (rank : 5)
Query Neighborhood Hits	74	Target Neighborhood Hits	162	Shared Neighborhood Hits	50
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

SPRL1_HUMAN
θ value	3.77169e-06 (rank : 12)	NC score	0.395238 (rank : 13)
Query Neighborhood Hits	74	Target Neighborhood Hits	231	Shared Neighborhood Hits	33
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SPRL1_MOUSE
θ value	4.92598e-06 (rank : 13)	NC score	0.346899 (rank : 21)
Query Neighborhood Hits	74	Target Neighborhood Hits	403	Shared Neighborhood Hits	27
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TICN3_HUMAN
θ value	4.92598e-06 (rank : 14)	NC score	0.382092 (rank : 15)
Query Neighborhood Hits	74	Target Neighborhood Hits	82	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TEFF2_MOUSE
θ value	1.09739e-05 (rank : 15)	NC score	0.417525 (rank : 10)
Query Neighborhood Hits	74	Target Neighborhood Hits	214	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEFF2_HUMAN
θ value	1.43324e-05 (rank : 16)	NC score	0.417095 (rank : 11)
Query Neighborhood Hits	74	Target Neighborhood Hits	211	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

MUC2_HUMAN
θ value	5.44631e-05 (rank : 17)	NC score	0.137326 (rank : 45)
Query Neighborhood Hits	74	Target Neighborhood Hits	906	Shared Neighborhood Hits	20
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

TICN3_MOUSE
θ value	5.44631e-05 (rank : 18)	NC score	0.384403 (rank : 14)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN2_MOUSE
θ value	9.29e-05 (rank : 19)	NC score	0.370106 (rank : 19)
Query Neighborhood Hits	74	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

CFAI_MOUSE
θ value	0.000158464 (rank : 20)	NC score	0.062314 (rank : 70)
Query Neighborhood Hits	74	Target Neighborhood Hits	290	Shared Neighborhood Hits	19
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

TICN2_HUMAN
θ value	0.000158464 (rank : 21)	NC score	0.359821 (rank : 20)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

ISK5_HUMAN
θ value	0.00102713 (rank : 22)	NC score	0.336552 (rank : 22)
Query Neighborhood Hits	74	Target Neighborhood Hits	89	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

SPRC_HUMAN
θ value	0.00134147 (rank : 23)	NC score	0.374957 (rank : 18)
Query Neighborhood Hits	74	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
θ value	0.00134147 (rank : 24)	NC score	0.375430 (rank : 17)
Query Neighborhood Hits	74	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SSPO_MOUSE
θ value	0.00228821 (rank : 25)	NC score	0.101139 (rank : 50)
Query Neighborhood Hits	74	Target Neighborhood Hits	800	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SMOC2_HUMAN
θ value	0.00869519 (rank : 26)	NC score	0.274189 (rank : 30)
Query Neighborhood Hits	74	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

KAZD1_MOUSE
θ value	0.0113563 (rank : 27)	NC score	0.200787 (rank : 37)
Query Neighborhood Hits	74	Target Neighborhood Hits	281	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

TICN1_MOUSE
θ value	0.0113563 (rank : 28)	NC score	0.315214 (rank : 24)
Query Neighborhood Hits	74	Target Neighborhood Hits	79	Shared Neighborhood Hits	38
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

ISK6_HUMAN
θ value	0.0252991 (rank : 29)	NC score	0.376296 (rank : 16)
Query Neighborhood Hits	74	Target Neighborhood Hits	32	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

ISK7_MOUSE
θ value	0.0252991 (rank : 30)	NC score	0.304579 (rank : 26)
Query Neighborhood Hits	74	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

TICN1_HUMAN
θ value	0.0252991 (rank : 31)	NC score	0.302658 (rank : 27)
Query Neighborhood Hits	74	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

SMOC2_MOUSE
θ value	0.0330416 (rank : 32)	NC score	0.270459 (rank : 33)
Query Neighborhood Hits	74	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

VWF_MOUSE
θ value	0.0431538 (rank : 33)	NC score	0.125138 (rank : 46)
Query Neighborhood Hits	74	Target Neighborhood Hits	381	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

IBP7_MOUSE
θ value	0.0563607 (rank : 34)	NC score	0.189685 (rank : 41)
Query Neighborhood Hits	74	Target Neighborhood Hits	230	Shared Neighborhood Hits	26
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

RECK_HUMAN
θ value	0.0563607 (rank : 35)	NC score	0.193523 (rank : 39)
Query Neighborhood Hits	74	Target Neighborhood Hits	189	Shared Neighborhood Hits	42
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

VWF_HUMAN
θ value	0.0563607 (rank : 36)	NC score	0.123640 (rank : 47)
Query Neighborhood Hits	74	Target Neighborhood Hits	396	Shared Neighborhood Hits	19
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MUC5B_HUMAN
θ value	0.0736092 (rank : 37)	NC score	0.117310 (rank : 48)
Query Neighborhood Hits	74	Target Neighborhood Hits	1020	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TINAG_HUMAN
θ value	0.125558 (rank : 38)	NC score	0.071069 (rank : 56)
Query Neighborhood Hits	74	Target Neighborhood Hits	63	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

FGD6_HUMAN
θ value	0.21417 (rank : 39)	NC score	0.041294 (rank : 91)
Query Neighborhood Hits	74	Target Neighborhood Hits	237	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

RECK_MOUSE
θ value	0.21417 (rank : 40)	NC score	0.181939 (rank : 42)
Query Neighborhood Hits	74	Target Neighborhood Hits	158	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

FGD6_MOUSE
θ value	0.279714 (rank : 41)	NC score	0.040379 (rank : 92)
Query Neighborhood Hits	74	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

ISK4_HUMAN
θ value	0.279714 (rank : 42)	NC score	0.315624 (rank : 23)
Query Neighborhood Hits	74	Target Neighborhood Hits	28	Shared Neighborhood Hits	25
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

KAZD1_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.198109 (rank : 38)
Query Neighborhood Hits	74	Target Neighborhood Hits	248	Shared Neighborhood Hits	35
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

SMOC1_MOUSE
θ value	0.365318 (rank : 44)	NC score	0.272926 (rank : 31)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

IPK2_HUMAN
θ value	0.47712 (rank : 45)	NC score	0.272460 (rank : 32)
Query Neighborhood Hits	74	Target Neighborhood Hits	30	Shared Neighborhood Hits	26
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

ISK7_HUMAN
θ value	0.47712 (rank : 46)	NC score	0.299204 (rank : 28)
Query Neighborhood Hits	74	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

NCS1_HUMAN
θ value	0.62314 (rank : 47)	NC score	0.032024 (rank : 96)
Query Neighborhood Hits	74	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	P62166, P36610, Q9UK26	Gene names	FREQ, FLUP, NCS1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein).

NCS1_MOUSE
θ value	0.62314 (rank : 48)	NC score	0.032024 (rank : 97)
Query Neighborhood Hits	74	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BNY6	Gene names	Freq, Ncs1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog).

ISK6_MOUSE
θ value	0.813845 (rank : 49)	NC score	0.309753 (rank : 25)
Query Neighborhood Hits	74	Target Neighborhood Hits	37	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

IBP7_HUMAN
θ value	1.06291 (rank : 50)	NC score	0.179164 (rank : 44)
Query Neighborhood Hits	74	Target Neighborhood Hits	220	Shared Neighborhood Hits	26
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

ISK4_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.265714 (rank : 34)
Query Neighborhood Hits	74	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

HTRA1_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.106749 (rank : 49)
Query Neighborhood Hits	74	Target Neighborhood Hits	140	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

JAG1_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.035640 (rank : 93)
Query Neighborhood Hits	74	Target Neighborhood Hits	518	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

SMOC1_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.259723 (rank : 35)
Query Neighborhood Hits	74	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

CFAI_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.032955 (rank : 95)
Query Neighborhood Hits	74	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

ATS20_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.014105 (rank : 106)
Query Neighborhood Hits	74	Target Neighborhood Hits	225	Shared Neighborhood Hits	7
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

CAR11_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.006606 (rank : 110)
Query Neighborhood Hits	74	Target Neighborhood Hits	690	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

CD244_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.030191 (rank : 101)
Query Neighborhood Hits	74	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q07763, O88654, Q9JIE0	Gene names	Cd244, 2b4, Nmrk
Domain Architecture
Description	Natural killer cell receptor 2B4 precursor (NKR2B4) (NK cell type I receptor protein 2B4) (CD244 antigen) (Non MHC restricted killing associated).

JAG1_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.034731 (rank : 94)
Query Neighborhood Hits	74	Target Neighborhood Hits	514	Shared Neighborhood Hits	19
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

CRIM1_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.078145 (rank : 55)
Query Neighborhood Hits	74	Target Neighborhood Hits	362	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

HTRA1_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.090864 (rank : 51)
Query Neighborhood Hits	74	Target Neighborhood Hits	155	Shared Neighborhood Hits	31
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

IPK2_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.190008 (rank : 40)
Query Neighborhood Hits	74	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BMY7	Gene names	Spink2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 2 precursor.

SO5A1_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.031156 (rank : 99)
Query Neighborhood Hits	74	Target Neighborhood Hits	57	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

CRDL2_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.031004 (rank : 100)
Query Neighborhood Hits	74	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

FBN3_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.028608 (rank : 102)
Query Neighborhood Hits	74	Target Neighborhood Hits	543	Shared Neighborhood Hits	23
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

IGFL3_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.017158 (rank : 105)
Query Neighborhood Hits	74	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UXB1	Gene names	IGFL3
Domain Architecture	No domain graphic available
Description	Insulin growth factor-like family member 3 precursor.

NOTC4_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.031555 (rank : 98)
Query Neighborhood Hits	74	Target Neighborhood Hits	872	Shared Neighborhood Hits	24
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

SO1B1_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.024687 (rank : 103)
Query Neighborhood Hits	74	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

ZAN_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.079009 (rank : 54)
Query Neighborhood Hits	74	Target Neighborhood Hits	808	Shared Neighborhood Hits	25
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CAYP2_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.012656 (rank : 108)
Query Neighborhood Hits	74	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BUG5, Q8C1J6	Gene names	Caps2
Domain Architecture	No domain graphic available
Description	Calcyphosin-2 (Calcyphosine-2).

DUOX1_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.009272 (rank : 109)
Query Neighborhood Hits	74	Target Neighborhood Hits	172	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRD9, Q6ZMB3, Q6ZR09, Q9NZC1	Gene names	DUOX1, DUOX, LNOX1, THOX1
Domain Architecture	No domain graphic available
Description	Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1) (Long NOX 1).

SO1B3_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.023159 (rank : 104)
Query Neighborhood Hits	74	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

TLR2_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.002876 (rank : 111)
Query Neighborhood Hits	74	Target Neighborhood Hits	290	Shared Neighborhood Hits	2
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

TNNC2_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.013766 (rank : 107)
Query Neighborhood Hits	74	Target Neighborhood Hits	234	Shared Neighborhood Hits	7
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

BMPER_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.070487 (rank : 58)
Query Neighborhood Hits	74	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.068211 (rank : 62)
Query Neighborhood Hits	74	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CI094_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.057609 (rank : 73)
Query Neighborhood Hits	74	Target Neighborhood Hits	310	Shared Neighborhood Hits	10
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

HG2A_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.086204 (rank : 53)
Query Neighborhood Hits	74	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

HG2A_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.089734 (rank : 52)
Query Neighborhood Hits	74	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

HTRA3_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.066622 (rank : 64)
Query Neighborhood Hits	74	Target Neighborhood Hits	152	Shared Neighborhood Hits	26
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.063324 (rank : 69)
Query Neighborhood Hits	74	Target Neighborhood Hits	156	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HTRA4_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.055893 (rank : 77)
Query Neighborhood Hits	74	Target Neighborhood Hits	119	Shared Neighborhood Hits	17
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

IBP1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.053959 (rank : 82)
Query Neighborhood Hits	74	Target Neighborhood Hits	67	Shared Neighborhood Hits	17
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.051977 (rank : 86)
Query Neighborhood Hits	74	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP2_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.050407 (rank : 89)
Query Neighborhood Hits	74	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP3_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.068165 (rank : 63)
Query Neighborhood Hits	74	Target Neighborhood Hits	67	Shared Neighborhood Hits	18
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP3_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.058953 (rank : 71)
Query Neighborhood Hits	74	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP5_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.056822 (rank : 76)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.055545 (rank : 78)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP6_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.064051 (rank : 67)
Query Neighborhood Hits	74	Target Neighborhood Hits	55	Shared Neighborhood Hits	15
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IPK1_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.213799 (rank : 36)
Query Neighborhood Hits	74	Target Neighborhood Hits	38	Shared Neighborhood Hits	29
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

ISK3_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.180353 (rank : 43)
Query Neighborhood Hits	74	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

JAM2_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.063435 (rank : 68)
Query Neighborhood Hits	74	Target Neighborhood Hits	304	Shared Neighborhood Hits	8
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

KR102_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.052050 (rank : 85)
Query Neighborhood Hits	74	Target Neighborhood Hits	264	Shared Neighborhood Hits	19
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.070432 (rank : 59)
Query Neighborhood Hits	74	Target Neighborhood Hits	313	Shared Neighborhood Hits	19
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR106_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.057068 (rank : 75)
Query Neighborhood Hits	74	Target Neighborhood Hits	347	Shared Neighborhood Hits	21
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR109_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.057795 (rank : 72)
Query Neighborhood Hits	74	Target Neighborhood Hits	226	Shared Neighborhood Hits	20
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10B_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.053798 (rank : 83)
Query Neighborhood Hits	74	Target Neighborhood Hits	269	Shared Neighborhood Hits	18
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KRA53_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.050236 (rank : 90)
Query Neighborhood Hits	74	Target Neighborhood Hits	331	Shared Neighborhood Hits	19
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA59_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.057211 (rank : 74)
Query Neighborhood Hits	74	Target Neighborhood Hits	310	Shared Neighborhood Hits	18
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

MOX2R_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.053193 (rank : 84)
Query Neighborhood Hits	74	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

NRG2_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.054345 (rank : 81)
Query Neighborhood Hits	74	Target Neighborhood Hits	419	Shared Neighborhood Hits	12
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.054752 (rank : 80)
Query Neighborhood Hits	74	Target Neighborhood Hits	392	Shared Neighborhood Hits	13
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

PUNC_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.051378 (rank : 87)
Query Neighborhood Hits	74	Target Neighborhood Hits	449	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

PUNC_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.050575 (rank : 88)
Query Neighborhood Hits	74	Target Neighborhood Hits	501	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

TACD1_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.054821 (rank : 79)
Query Neighborhood Hits	74	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

TECTA_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.069600 (rank : 60)
Query Neighborhood Hits	74	Target Neighborhood Hits	239	Shared Neighborhood Hits	14
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.064357 (rank : 66)
Query Neighborhood Hits	74	Target Neighborhood Hits	244	Shared Neighborhood Hits	13
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TMIGD_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.070663 (rank : 57)
Query Neighborhood Hits	74	Target Neighborhood Hits	240	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TMIGD_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.064551 (rank : 65)
Query Neighborhood Hits	74	Target Neighborhood Hits	234	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

ZAN_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.068232 (rank : 61)
Query Neighborhood Hits	74	Target Neighborhood Hits	679	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

FSTL1_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.84073e-178 (rank : 1)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	74
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FSTL1_HUMAN
NC score	0.998705 (rank : 2)	θ value	1.08415e-162 (rank : 2)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	67
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FST_HUMAN
NC score	0.603605 (rank : 3)	θ value	9.26847e-13 (rank : 7)
Query Neighborhood Hits	74	Target Neighborhood Hits	129	Shared Neighborhood Hits	51
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
NC score	0.602572 (rank : 4)	θ value	1.2105e-12 (rank : 8)
Query Neighborhood Hits	74	Target Neighborhood Hits	146	Shared Neighborhood Hits	52
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FSTL3_HUMAN
NC score	0.550021 (rank : 5)	θ value	1.99992e-07 (rank : 11)
Query Neighborhood Hits	74	Target Neighborhood Hits	162	Shared Neighborhood Hits	50
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
NC score	0.540986 (rank : 6)	θ value	1.53129e-07 (rank : 10)
Query Neighborhood Hits	74	Target Neighborhood Hits	152	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL4_HUMAN
NC score	0.432534 (rank : 7)	θ value	2.5182e-18 (rank : 3)
Query Neighborhood Hits	74	Target Neighborhood Hits	344	Shared Neighborhood Hits	41
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL4_MOUSE
NC score	0.429704 (rank : 8)	θ value	6.85773e-16 (rank : 6)
Query Neighborhood Hits	74	Target Neighborhood Hits	333	Shared Neighborhood Hits	40
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL5_HUMAN
NC score	0.419550 (rank : 9)	θ value	4.29542e-18 (rank : 4)
Query Neighborhood Hits	74	Target Neighborhood Hits	347	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

TEFF2_MOUSE
NC score	0.417525 (rank : 10)	θ value	1.09739e-05 (rank : 15)
Query Neighborhood Hits	74	Target Neighborhood Hits	214	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEFF2_HUMAN
NC score	0.417095 (rank : 11)	θ value	1.43324e-05 (rank : 16)
Query Neighborhood Hits	74	Target Neighborhood Hits	211	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

FSTL5_MOUSE
NC score	0.415709 (rank : 12)	θ value	2.13179e-17 (rank : 5)
Query Neighborhood Hits	74	Target Neighborhood Hits	355	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

SPRL1_HUMAN
NC score	0.395238 (rank : 13)	θ value	3.77169e-06 (rank : 12)
Query Neighborhood Hits	74	Target Neighborhood Hits	231	Shared Neighborhood Hits	33
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

TICN3_MOUSE
NC score	0.384403 (rank : 14)	θ value	5.44631e-05 (rank : 18)
Query Neighborhood Hits	74	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_HUMAN
NC score	0.382092 (rank : 15)	θ value	4.92598e-06 (rank : 14)
Query Neighborhood Hits	74	Target Neighborhood Hits	82	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

ISK6_HUMAN
NC score	0.376296 (rank : 16)	θ value	0.0252991 (rank : 29)
Query Neighborhood Hits	74	Target Neighborhood Hits	32	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

SPRC_MOUSE
NC score	0.375430 (rank : 17)	θ value	0.00134147 (rank : 24)
Query Neighborhood Hits	74	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_HUMAN
NC score	0.374957 (rank : 18)	θ value	0.00134147 (rank : 23)
Query Neighborhood Hits	74	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

TICN2_MOUSE
NC score	0.370106 (rank : 19)	θ value	9.29e-05 (rank : 19)
Query Neighborhood Hits	74	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_HUMAN
NC score	0.359821 (rank : 20)	θ value	0.000158464 (rank : 21)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

SPRL1_MOUSE
NC score	0.346899 (rank : 21)	θ value	4.92598e-06 (rank : 13)
Query Neighborhood Hits	74	Target Neighborhood Hits	403	Shared Neighborhood Hits	27
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

ISK5_HUMAN
NC score	0.336552 (rank : 22)	θ value	0.00102713 (rank : 22)
Query Neighborhood Hits	74	Target Neighborhood Hits	89	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

ISK4_HUMAN
NC score	0.315624 (rank : 23)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	74	Target Neighborhood Hits	28	Shared Neighborhood Hits	25
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

TICN1_MOUSE
NC score	0.315214 (rank : 24)	θ value	0.0113563 (rank : 28)
Query Neighborhood Hits	74	Target Neighborhood Hits	79	Shared Neighborhood Hits	38
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

ISK6_MOUSE
NC score	0.309753 (rank : 25)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	74	Target Neighborhood Hits	37	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

ISK7_MOUSE
NC score	0.304579 (rank : 26)	θ value	0.0252991 (rank : 30)
Query Neighborhood Hits	74	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

TICN1_HUMAN
NC score	0.302658 (rank : 27)	θ value	0.0252991 (rank : 31)
Query Neighborhood Hits	74	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

ISK7_HUMAN
NC score	0.299204 (rank : 28)	θ value	0.47712 (rank : 46)
Query Neighborhood Hits	74	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

AGRIN_HUMAN
NC score	0.274385 (rank : 29)	θ value	2.13673e-09 (rank : 9)
Query Neighborhood Hits	74	Target Neighborhood Hits	582	Shared Neighborhood Hits	60
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

SMOC2_HUMAN
NC score	0.274189 (rank : 30)	θ value	0.00869519 (rank : 26)
Query Neighborhood Hits	74	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC1_MOUSE
NC score	0.272926 (rank : 31)	θ value	0.365318 (rank : 44)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

IPK2_HUMAN
NC score	0.272460 (rank : 32)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	74	Target Neighborhood Hits	30	Shared Neighborhood Hits	26
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

SMOC2_MOUSE
NC score	0.270459 (rank : 33)	θ value	0.0330416 (rank : 32)
Query Neighborhood Hits	74	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

ISK4_MOUSE
NC score	0.265714 (rank : 34)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	74	Target Neighborhood Hits	28	Shared Neighborhood Hits	26
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

SMOC1_HUMAN
NC score	0.259723 (rank : 35)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	74	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

IPK1_HUMAN
NC score	0.213799 (rank : 36)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	74	Target Neighborhood Hits	38	Shared Neighborhood Hits	29
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

KAZD1_MOUSE
NC score	0.200787 (rank : 37)	θ value	0.0113563 (rank : 27)
Query Neighborhood Hits	74	Target Neighborhood Hits	281	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KAZD1_HUMAN
NC score	0.198109 (rank : 38)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	74	Target Neighborhood Hits	248	Shared Neighborhood Hits	35
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

RECK_HUMAN
NC score	0.193523 (rank : 39)	θ value	0.0563607 (rank : 35)
Query Neighborhood Hits	74	Target Neighborhood Hits	189	Shared Neighborhood Hits	42
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

IPK2_MOUSE
NC score	0.190008 (rank : 40)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	74	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BMY7	Gene names	Spink2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 2 precursor.

IBP7_MOUSE
NC score	0.189685 (rank : 41)	θ value	0.0563607 (rank : 34)
Query Neighborhood Hits	74	Target Neighborhood Hits	230	Shared Neighborhood Hits	26
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

RECK_MOUSE
NC score	0.181939 (rank : 42)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	74	Target Neighborhood Hits	158	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

ISK3_MOUSE
NC score	0.180353 (rank : 43)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	74	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

IBP7_HUMAN
NC score	0.179164 (rank : 44)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	74	Target Neighborhood Hits	220	Shared Neighborhood Hits	26
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

MUC2_HUMAN
NC score	0.137326 (rank : 45)	θ value	5.44631e-05 (rank : 17)
Query Neighborhood Hits	74	Target Neighborhood Hits	906	Shared Neighborhood Hits	20
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

VWF_MOUSE
NC score	0.125138 (rank : 46)	θ value	0.0431538 (rank : 33)
Query Neighborhood Hits	74	Target Neighborhood Hits	381	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_HUMAN
NC score	0.123640 (rank : 47)	θ value	0.0563607 (rank : 36)
Query Neighborhood Hits	74	Target Neighborhood Hits	396	Shared Neighborhood Hits	19
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MUC5B_HUMAN
NC score	0.117310 (rank : 48)	θ value	0.0736092 (rank : 37)
Query Neighborhood Hits	74	Target Neighborhood Hits	1020	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

HTRA1_MOUSE
NC score	0.106749 (rank : 49)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	74	Target Neighborhood Hits	140	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

SSPO_MOUSE
NC score	0.101139 (rank : 50)	θ value	0.00228821 (rank : 25)
Query Neighborhood Hits	74	Target Neighborhood Hits	800	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

HTRA1_HUMAN
NC score	0.090864 (rank : 51)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	74	Target Neighborhood Hits	155	Shared Neighborhood Hits	31
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HG2A_MOUSE
NC score	0.089734 (rank : 52)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	74	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

HG2A_HUMAN
NC score	0.086204 (rank : 53)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	74	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

ZAN_MOUSE
NC score	0.079009 (rank : 54)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	74	Target Neighborhood Hits	808	Shared Neighborhood Hits	25
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CRIM1_HUMAN
NC score	0.078145 (rank : 55)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	74	Target Neighborhood Hits	362	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

TINAG_HUMAN
NC score	0.071069 (rank : 56)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	74	Target Neighborhood Hits	63	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

TMIGD_HUMAN
NC score	0.070663 (rank : 57)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	74	Target Neighborhood Hits	240	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

BMPER_HUMAN
NC score	0.070487 (rank : 58)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	74	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

KR104_HUMAN
NC score	0.070432 (rank : 59)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	74	Target Neighborhood Hits	313	Shared Neighborhood Hits	19
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

TECTA_HUMAN
NC score	0.069600 (rank : 60)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	74	Target Neighborhood Hits	239	Shared Neighborhood Hits	14
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

ZAN_HUMAN
NC score	0.068232 (rank : 61)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	74	Target Neighborhood Hits	679	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

BMPER_MOUSE
NC score	0.068211 (rank : 62)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	74	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

IBP3_HUMAN
NC score	0.068165 (rank : 63)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	74	Target Neighborhood Hits	67	Shared Neighborhood Hits	18
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

HTRA3_HUMAN
NC score	0.066622 (rank : 64)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	74	Target Neighborhood Hits	152	Shared Neighborhood Hits	26
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

TMIGD_MOUSE
NC score	0.064551 (rank : 65)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	74	Target Neighborhood Hits	234	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TECTA_MOUSE
NC score	0.064357 (rank : 66)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	74	Target Neighborhood Hits	244	Shared Neighborhood Hits	13
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

IBP6_HUMAN
NC score	0.064051 (rank : 67)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	74	Target Neighborhood Hits	55	Shared Neighborhood Hits	15
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

JAM2_HUMAN
NC score	0.063435 (rank : 68)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	74	Target Neighborhood Hits	304	Shared Neighborhood Hits	8
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

HTRA3_MOUSE
NC score	0.063324 (rank : 69)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	74	Target Neighborhood Hits	156	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

CFAI_MOUSE
NC score	0.062314 (rank : 70)	θ value	0.000158464 (rank : 20)
Query Neighborhood Hits	74	Target Neighborhood Hits	290	Shared Neighborhood Hits	19
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

IBP3_MOUSE
NC score	0.058953 (rank : 71)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	74	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

KR109_HUMAN
NC score	0.057795 (rank : 72)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	74	Target Neighborhood Hits	226	Shared Neighborhood Hits	20
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

CI094_HUMAN
NC score	0.057609 (rank : 73)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	74	Target Neighborhood Hits	310	Shared Neighborhood Hits	10
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

KRA59_HUMAN
NC score	0.057211 (rank : 74)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	74	Target Neighborhood Hits	310	Shared Neighborhood Hits	18
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KR106_HUMAN
NC score	0.057068 (rank : 75)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	74	Target Neighborhood Hits	347	Shared Neighborhood Hits	21
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

IBP5_HUMAN
NC score	0.056822 (rank : 76)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

HTRA4_HUMAN
NC score	0.055893 (rank : 77)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	74	Target Neighborhood Hits	119	Shared Neighborhood Hits	17
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

IBP5_MOUSE
NC score	0.055545 (rank : 78)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

TACD1_HUMAN
NC score	0.054821 (rank : 79)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	74	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

NRG2_MOUSE
NC score	0.054752 (rank : 80)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	74	Target Neighborhood Hits	392	Shared Neighborhood Hits	13
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG2_HUMAN
NC score	0.054345 (rank : 81)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	74	Target Neighborhood Hits	419	Shared Neighborhood Hits	12
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

IBP1_HUMAN
NC score	0.053959 (rank : 82)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	74	Target Neighborhood Hits	67	Shared Neighborhood Hits	17
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

KR10B_HUMAN
NC score	0.053798 (rank : 83)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	74	Target Neighborhood Hits	269	Shared Neighborhood Hits	18
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

MOX2R_MOUSE
NC score	0.053193 (rank : 84)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	74	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

KR102_HUMAN
NC score	0.052050 (rank : 85)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	74	Target Neighborhood Hits	264	Shared Neighborhood Hits	19
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

IBP1_MOUSE
NC score	0.051977 (rank : 86)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	74	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

PUNC_HUMAN
NC score	0.051378 (rank : 87)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	74	Target Neighborhood Hits	449	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

PUNC_MOUSE
NC score	0.050575 (rank : 88)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	74	Target Neighborhood Hits	501	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

IBP2_MOUSE
NC score	0.050407 (rank : 89)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	74	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

KRA53_HUMAN
NC score	0.050236 (rank : 90)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	74	Target Neighborhood Hits	331	Shared Neighborhood Hits	19
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

FGD6_HUMAN
NC score	0.041294 (rank : 91)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	74	Target Neighborhood Hits	237	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
NC score	0.040379 (rank : 92)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	74	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

JAG1_MOUSE
NC score	0.035640 (rank : 93)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	74	Target Neighborhood Hits	518	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG1_HUMAN
NC score	0.034731 (rank : 94)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	74	Target Neighborhood Hits	514	Shared Neighborhood Hits	19
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

CFAI_HUMAN
NC score	0.032955 (rank : 95)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	74	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

NCS1_HUMAN
NC score	0.032024 (rank : 96)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	74	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	P62166, P36610, Q9UK26	Gene names	FREQ, FLUP, NCS1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein).

NCS1_MOUSE
NC score	0.032024 (rank : 97)	θ value	0.62314 (rank : 48)
Query Neighborhood Hits	74	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BNY6	Gene names	Freq, Ncs1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog).

NOTC4_MOUSE
NC score	0.031555 (rank : 98)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	74	Target Neighborhood Hits	872	Shared Neighborhood Hits	24
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

SO5A1_HUMAN
NC score	0.031156 (rank : 99)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	74	Target Neighborhood Hits	57	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

CRDL2_MOUSE
NC score	0.031004 (rank : 100)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	74	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CD244_MOUSE
NC score	0.030191 (rank : 101)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	74	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q07763, O88654, Q9JIE0	Gene names	Cd244, 2b4, Nmrk
Domain Architecture
Description	Natural killer cell receptor 2B4 precursor (NKR2B4) (NK cell type I receptor protein 2B4) (CD244 antigen) (Non MHC restricted killing associated).

FBN3_HUMAN
NC score	0.028608 (rank : 102)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	74	Target Neighborhood Hits	543	Shared Neighborhood Hits	23
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

SO1B1_HUMAN
NC score	0.024687 (rank : 103)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	74	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

SO1B3_HUMAN
NC score	0.023159 (rank : 104)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	74	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

IGFL3_HUMAN
NC score	0.017158 (rank : 105)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	74	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UXB1	Gene names	IGFL3
Domain Architecture	No domain graphic available
Description	Insulin growth factor-like family member 3 precursor.

ATS20_MOUSE
NC score	0.014105 (rank : 106)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	74	Target Neighborhood Hits	225	Shared Neighborhood Hits	7
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

TNNC2_HUMAN
NC score	0.013766 (rank : 107)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	74	Target Neighborhood Hits	234	Shared Neighborhood Hits	7
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

CAYP2_MOUSE
NC score	0.012656 (rank : 108)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	74	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BUG5, Q8C1J6	Gene names	Caps2
Domain Architecture	No domain graphic available
Description	Calcyphosin-2 (Calcyphosine-2).

DUOX1_HUMAN
NC score	0.009272 (rank : 109)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	74	Target Neighborhood Hits	172	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRD9, Q6ZMB3, Q6ZR09, Q9NZC1	Gene names	DUOX1, DUOX, LNOX1, THOX1
Domain Architecture	No domain graphic available
Description	Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1) (Long NOX 1).

CAR11_HUMAN
NC score	0.006606 (rank : 110)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	74	Target Neighborhood Hits	690	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXL7, Q548H3	Gene names	CARD11, CARMA1
Domain Architecture
Description	Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 3) (Carma 1).

TLR2_HUMAN
NC score	0.002876 (rank : 111)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	74	Target Neighborhood Hits	290	Shared Neighborhood Hits	2
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).