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Network neighborhood for query Sequence : SO1B1_HUMAN

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SO1B1_HUMAN
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SO1B1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

SO1B2_MOUSE
θ value	0 (rank : 2)	NC score	0.997799 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJL3, Q9JI79, Q9JJJ1	Gene names	Slco1b2, Slc21a10
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B2 (Solute carrier family 21 member 10) (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6).

SO1B3_HUMAN
θ value	0 (rank : 3)	NC score	0.998934 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

SO1C1_HUMAN
θ value	4.39142e-172 (rank : 4)	NC score	0.991591 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYB5	Gene names	SLCO1C1, OATPF, SLC21A14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5).

SO1C1_MOUSE
θ value	9.47563e-167 (rank : 5)	NC score	0.991143 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

SO1A5_MOUSE
θ value	7.28896e-151 (rank : 6)	NC score	0.985702 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YY5, Q91XS2	Gene names	Slco1a5, Oatp3, Slc21a7
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A5 (Solute carrier family 21 member 7) (Sodium-independent organic anion transporter 3) (Organic anion-transporting polypeptide 3).

SO1A4_MOUSE
θ value	9.22056e-146 (rank : 7)	NC score	0.985137 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EP96	Gene names	Slco1a4, Oatp2, Slc21a5
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A4 (Solute carrier family 21 member 5) (Sodium-independent organic anion- transporting polypeptide 2).

SO1A2_HUMAN
θ value	9.54178e-143 (rank : 8)	NC score	0.985537 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

SO1A6_MOUSE
θ value	8.0776e-142 (rank : 9)	NC score	0.985055 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

SO1A1_MOUSE
θ value	6.83811e-141 (rank : 10)	NC score	0.985191 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SO3A1_MOUSE
θ value	4.80189e-94 (rank : 11)	NC score	0.971534 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

SO3A1_HUMAN
θ value	2.63489e-92 (rank : 12)	NC score	0.971157 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

SO2A1_MOUSE
θ value	2.23057e-91 (rank : 13)	NC score	0.968424 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	51	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO2B1_MOUSE
θ value	1.00358e-83 (rank : 14)	NC score	0.964006 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).

SO2A1_HUMAN
θ value	8.79181e-80 (rank : 15)	NC score	0.968363 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO5A1_HUMAN
θ value	8.22888e-78 (rank : 16)	NC score	0.964720 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	57	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

SO2B1_HUMAN
θ value	2.02684e-76 (rank : 17)	NC score	0.963000 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	O94956, Q9H2Z0, Q9UFU1	Gene names	SLCO2B1, KIAA0880, OATPB, SLC21A9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9) (Organic anion transporter B) (OATP-B) (Organic anion transporter polypeptide-related protein 2) (OATP-RP2) (OATPRP2).

SO4A1_HUMAN
θ value	1.5555e-68 (rank : 18)	NC score	0.954721 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	54	Shared Neighborhood Hits	25
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

SO4A1_MOUSE
θ value	4.38363e-63 (rank : 19)	NC score	0.955003 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

RECK_HUMAN
θ value	0.0252991 (rank : 20)	NC score	0.155670 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	189	Shared Neighborhood Hits	27
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

GTR2_HUMAN
θ value	0.0330416 (rank : 21)	NC score	0.030032 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	P11168	Gene names	SLC2A2, GLUT2
Domain Architecture
Description	Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver).

RECK_MOUSE
θ value	0.21417 (rank : 22)	NC score	0.126616 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	158	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

AGRIN_HUMAN
θ value	0.62314 (rank : 23)	NC score	0.052665 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	582	Shared Neighborhood Hits	31
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

TEFF2_MOUSE
θ value	1.06291 (rank : 24)	NC score	0.080913 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	214	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TAP2_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.003756 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

TEFF2_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.081457 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	211	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TR123_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.003786 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	P59528, Q7M714	Gene names	Tas2r123, T2r55, Tas2r23
Domain Architecture
Description	Taste receptor type 2 member 123 (T2R123) (Taste receptor type 2 member 23) (T2R23) (mT2R55) (STC9-2).

UN93B_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.015177 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1C4, O95764, Q710D4	Gene names	UNC93B1, UNC93, UNC93B
Domain Architecture	No domain graphic available
Description	UNC93 homolog B1 (UNC-93B protein) (hUNC93B1).

UN93B_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.015027 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCW4, O89077, Q710D2, Q8CIK1, Q8R3D0	Gene names	Unc93b1, Unc93b
Domain Architecture	No domain graphic available
Description	UNC93 homolog B1 (UNC-93B protein).

EI24_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.022122 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O14681	Gene names	EI24, PIG8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

FST_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.057852 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	146	Shared Neighborhood Hits	25
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

EI24_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.013260 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q61070	Gene names	Ei24, Pig8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

EMR3_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.001171 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	245	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

FSTL1_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.024687 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	74	Shared Neighborhood Hits	16
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FSTL3_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.025042 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	162	Shared Neighborhood Hits	17
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.050002 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	129	Shared Neighborhood Hits	24
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FSTL1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.024382 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	68	Shared Neighborhood Hits	16
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL5_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.012472 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	347	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.014693 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	355	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

IBP7_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.039377 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	230	Shared Neighborhood Hits	21
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

S22A9_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.004135 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IVM8, Q8TEC0, Q8WYN7	Gene names	SLC22A9, OAT4, UST3
Domain Architecture	No domain graphic available
Description	Solute carrier family 22 member 9 (Organic anion transporter 4).

SLIT2_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.000104 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	684	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TR110_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.002528 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q7M712, Q71QD1	Gene names	Tas2r110
Domain Architecture	No domain graphic available
Description	Taste receptor type 2 member 110 (T2R110) (mT2r57) (STC 9-1).

IPK1_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.051856 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

ISK3_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.055477 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

Hits sorted by NC score

SO1B1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

SO1B3_HUMAN
NC score	0.998934 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

SO1B2_MOUSE
NC score	0.997799 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JJL3, Q9JI79, Q9JJJ1	Gene names	Slco1b2, Slc21a10
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B2 (Solute carrier family 21 member 10) (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6).

SO1C1_HUMAN
NC score	0.991591 (rank : 4)	θ value	4.39142e-172 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYB5	Gene names	SLCO1C1, OATPF, SLC21A14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5).

SO1C1_MOUSE
NC score	0.991143 (rank : 5)	θ value	9.47563e-167 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

SO1A5_MOUSE
NC score	0.985702 (rank : 6)	θ value	7.28896e-151 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YY5, Q91XS2	Gene names	Slco1a5, Oatp3, Slc21a7
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A5 (Solute carrier family 21 member 7) (Sodium-independent organic anion transporter 3) (Organic anion-transporting polypeptide 3).

SO1A2_HUMAN
NC score	0.985537 (rank : 7)	θ value	9.54178e-143 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

SO1A1_MOUSE
NC score	0.985191 (rank : 8)	θ value	6.83811e-141 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SO1A4_MOUSE
NC score	0.985137 (rank : 9)	θ value	9.22056e-146 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EP96	Gene names	Slco1a4, Oatp2, Slc21a5
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A4 (Solute carrier family 21 member 5) (Sodium-independent organic anion- transporting polypeptide 2).

SO1A6_MOUSE
NC score	0.985055 (rank : 10)	θ value	8.0776e-142 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

SO3A1_MOUSE
NC score	0.971534 (rank : 11)	θ value	4.80189e-94 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

SO3A1_HUMAN
NC score	0.971157 (rank : 12)	θ value	2.63489e-92 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

SO2A1_MOUSE
NC score	0.968424 (rank : 13)	θ value	2.23057e-91 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	51	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO2A1_HUMAN
NC score	0.968363 (rank : 14)	θ value	8.79181e-80 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO5A1_HUMAN
NC score	0.964720 (rank : 15)	θ value	8.22888e-78 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	57	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

SO2B1_MOUSE
NC score	0.964006 (rank : 16)	θ value	1.00358e-83 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).

SO2B1_HUMAN
NC score	0.963000 (rank : 17)	θ value	2.02684e-76 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	O94956, Q9H2Z0, Q9UFU1	Gene names	SLCO2B1, KIAA0880, OATPB, SLC21A9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9) (Organic anion transporter B) (OATP-B) (Organic anion transporter polypeptide-related protein 2) (OATP-RP2) (OATPRP2).

SO4A1_MOUSE
NC score	0.955003 (rank : 18)	θ value	4.38363e-63 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

SO4A1_HUMAN
NC score	0.954721 (rank : 19)	θ value	1.5555e-68 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	54	Shared Neighborhood Hits	25
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

RECK_HUMAN
NC score	0.155670 (rank : 20)	θ value	0.0252991 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	189	Shared Neighborhood Hits	27
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
NC score	0.126616 (rank : 21)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	158	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TEFF2_HUMAN
NC score	0.081457 (rank : 22)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	211	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
NC score	0.080913 (rank : 23)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	214	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

FST_MOUSE
NC score	0.057852 (rank : 24)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	146	Shared Neighborhood Hits	25
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ISK3_MOUSE
NC score	0.055477 (rank : 25)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

AGRIN_HUMAN
NC score	0.052665 (rank : 26)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	582	Shared Neighborhood Hits	31
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

IPK1_HUMAN
NC score	0.051856 (rank : 27)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

FST_HUMAN
NC score	0.050002 (rank : 28)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	129	Shared Neighborhood Hits	24
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

IBP7_MOUSE
NC score	0.039377 (rank : 29)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	230	Shared Neighborhood Hits	21
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

GTR2_HUMAN
NC score	0.030032 (rank : 30)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	P11168	Gene names	SLC2A2, GLUT2
Domain Architecture
Description	Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver).

FSTL3_HUMAN
NC score	0.025042 (rank : 31)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	162	Shared Neighborhood Hits	17
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL1_MOUSE
NC score	0.024687 (rank : 32)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	74	Shared Neighborhood Hits	16
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FSTL1_HUMAN
NC score	0.024382 (rank : 33)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	68	Shared Neighborhood Hits	16
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

EI24_HUMAN
NC score	0.022122 (rank : 34)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O14681	Gene names	EI24, PIG8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

UN93B_HUMAN
NC score	0.015177 (rank : 35)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1C4, O95764, Q710D4	Gene names	UNC93B1, UNC93, UNC93B
Domain Architecture	No domain graphic available
Description	UNC93 homolog B1 (UNC-93B protein) (hUNC93B1).

UN93B_MOUSE
NC score	0.015027 (rank : 36)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCW4, O89077, Q710D2, Q8CIK1, Q8R3D0	Gene names	Unc93b1, Unc93b
Domain Architecture	No domain graphic available
Description	UNC93 homolog B1 (UNC-93B protein).

FSTL5_MOUSE
NC score	0.014693 (rank : 37)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	355	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

EI24_MOUSE
NC score	0.013260 (rank : 38)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q61070	Gene names	Ei24, Pig8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

FSTL5_HUMAN
NC score	0.012472 (rank : 39)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	347	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

S22A9_HUMAN
NC score	0.004135 (rank : 40)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IVM8, Q8TEC0, Q8WYN7	Gene names	SLC22A9, OAT4, UST3
Domain Architecture	No domain graphic available
Description	Solute carrier family 22 member 9 (Organic anion transporter 4).

TR123_MOUSE
NC score	0.003786 (rank : 41)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	P59528, Q7M714	Gene names	Tas2r123, T2r55, Tas2r23
Domain Architecture
Description	Taste receptor type 2 member 123 (T2R123) (Taste receptor type 2 member 23) (T2R23) (mT2R55) (STC9-2).

TAP2_HUMAN
NC score	0.003756 (rank : 42)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

TR110_MOUSE
NC score	0.002528 (rank : 43)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q7M712, Q71QD1	Gene names	Tas2r110
Domain Architecture	No domain graphic available
Description	Taste receptor type 2 member 110 (T2R110) (mT2r57) (STC 9-1).

EMR3_HUMAN
NC score	0.001171 (rank : 44)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	245	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

SLIT2_MOUSE
NC score	0.000104 (rank : 45)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	684	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].