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Network neighborhood for query Sequence : SO1C1_MOUSE

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SO1C1_MOUSE
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SO1C1_HUMAN
θ value	0 (rank : 1)	NC score	0.999112 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	32	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NYB5	Gene names	SLCO1C1, OATPF, SLC21A14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5).

SO1C1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

SO1B3_HUMAN
θ value	2.17943e-171 (rank : 3)	NC score	0.990993 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

SO1A5_MOUSE
θ value	3.84704e-168 (rank : 4)	NC score	0.988837 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YY5, Q91XS2	Gene names	Slco1a5, Oatp3, Slc21a7
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A5 (Solute carrier family 21 member 7) (Sodium-independent organic anion transporter 3) (Organic anion-transporting polypeptide 3).

SO1B1_HUMAN
θ value	9.47563e-167 (rank : 5)	NC score	0.991143 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

SO1B2_MOUSE
θ value	2.11095e-166 (rank : 6)	NC score	0.990999 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	39	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JJL3, Q9JI79, Q9JJJ1	Gene names	Slco1b2, Slc21a10
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B2 (Solute carrier family 21 member 10) (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6).

SO1A2_HUMAN
θ value	6.7907e-165 (rank : 7)	NC score	0.989208 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	27
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

SO1A1_MOUSE
θ value	1.28067e-163 (rank : 8)	NC score	0.988589 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SO1A4_MOUSE
θ value	7.76955e-161 (rank : 9)	NC score	0.988100 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EP96	Gene names	Slco1a4, Oatp2, Slc21a5
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A4 (Solute carrier family 21 member 5) (Sodium-independent organic anion- transporting polypeptide 2).

SO1A6_MOUSE
θ value	2.42085e-154 (rank : 10)	NC score	0.988172 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

SO3A1_MOUSE
θ value	3.00075e-104 (rank : 11)	NC score	0.975228 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

SO3A1_HUMAN
θ value	3.91911e-104 (rank : 12)	NC score	0.975018 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

SO2A1_HUMAN
θ value	2.46047e-98 (rank : 13)	NC score	0.973686 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO2A1_MOUSE
θ value	5.48135e-98 (rank : 14)	NC score	0.972635 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	51	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO2B1_MOUSE
θ value	2.72669e-89 (rank : 15)	NC score	0.968117 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).

SO2B1_HUMAN
θ value	4.81303e-86 (rank : 16)	NC score	0.967245 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	O94956, Q9H2Z0, Q9UFU1	Gene names	SLCO2B1, KIAA0880, OATPB, SLC21A9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9) (Organic anion transporter B) (OATP-B) (Organic anion transporter polypeptide-related protein 2) (OATP-RP2) (OATPRP2).

SO5A1_HUMAN
θ value	4.07447e-85 (rank : 17)	NC score	0.968108 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	57	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

SO4A1_MOUSE
θ value	5.69867e-79 (rank : 18)	NC score	0.960878 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

SO4A1_HUMAN
θ value	1.26953e-78 (rank : 19)	NC score	0.959976 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

RECK_HUMAN
θ value	0.0431538 (rank : 20)	NC score	0.153020 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	189	Shared Neighborhood Hits	25
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	0.21417 (rank : 21)	NC score	0.124670 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	158	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

MOT1_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.012369 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P53985, Q9NSJ9	Gene names	SLC16A1, MCT1
Domain Architecture
Description	Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1).

FST_MOUSE
θ value	0.47712 (rank : 23)	NC score	0.059380 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	146	Shared Neighborhood Hits	20
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

VPP2_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.018686 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y487	Gene names	ATP6V0A2
Domain Architecture
Description	Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2 (V- ATPase 116 kDa isoform a2) (TJ6).

PPRB_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.018863 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	311	Shared Neighborhood Hits	3
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

FST_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.050812 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	129	Shared Neighborhood Hits	19
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

PPRB_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.016687 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	354	Shared Neighborhood Hits	3
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

AGRIN_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.049773 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	582	Shared Neighborhood Hits	27
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

FINC_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.003389 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	302	Shared Neighborhood Hits	3
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

OR8I2_HUMAN
θ value	3.0926 (rank : 30)	NC score	-0.002584 (rank : 43)
Query Neighborhood Hits	41	Target Neighborhood Hits	700	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N0Y5, Q96RC5	Gene names	OR8I2
Domain Architecture
Description	Olfactory receptor 8I2.

VPP2_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.015230 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P15920, Q3U2X3, Q9JHJ2	Gene names	Atp6v0a2, Atp6n1b, Tj6
Domain Architecture
Description	Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2 (V- ATPase 116 kDa isoform a2) (Immune suppressor factor J6B7).

TEFF2_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.074640 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	211	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

GTR4_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.003541 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	P14672	Gene names	SLC2A4, GLUT4
Domain Architecture
Description	Solute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4, insulin-responsive).

IBP7_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.038078 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	230	Shared Neighborhood Hits	17
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

CRBB1_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.003365 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P53674	Gene names	CRYBB1
Domain Architecture
Description	Beta crystallin B1.

IRK4_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.001833 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P48050	Gene names	KCNJ4
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (Hippocampal inward rectifier) (HIR) (HRK1) (HIRK2).

TEFF2_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.073127 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	214	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

GAS1_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.011125 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q01721	Gene names	Gas1, Gas-1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

NPT4_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.004163 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	O00476	Gene names	SLC17A3, NPT4
Domain Architecture	No domain graphic available
Description	Sodium-dependent phosphate transport protein 4 (Sodium/phosphate cotransporter 4) (Na(+)/PI cotransporter 4) (Solute carrier family 17 member 3).

ZAN_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.003546 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	679	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.003348 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	808	Shared Neighborhood Hits	11
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

IPK1_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.051459 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

ISK3_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.055372 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

Hits sorted by NC score

SO1C1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

SO1C1_HUMAN
NC score	0.999112 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	32	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NYB5	Gene names	SLCO1C1, OATPF, SLC21A14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5).

SO1B1_HUMAN
NC score	0.991143 (rank : 3)	θ value	9.47563e-167 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

SO1B2_MOUSE
NC score	0.990999 (rank : 4)	θ value	2.11095e-166 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	39	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JJL3, Q9JI79, Q9JJJ1	Gene names	Slco1b2, Slc21a10
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B2 (Solute carrier family 21 member 10) (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6).

SO1B3_HUMAN
NC score	0.990993 (rank : 5)	θ value	2.17943e-171 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

SO1A2_HUMAN
NC score	0.989208 (rank : 6)	θ value	6.7907e-165 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	27
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

SO1A5_MOUSE
NC score	0.988837 (rank : 7)	θ value	3.84704e-168 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YY5, Q91XS2	Gene names	Slco1a5, Oatp3, Slc21a7
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A5 (Solute carrier family 21 member 7) (Sodium-independent organic anion transporter 3) (Organic anion-transporting polypeptide 3).

SO1A1_MOUSE
NC score	0.988589 (rank : 8)	θ value	1.28067e-163 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SO1A6_MOUSE
NC score	0.988172 (rank : 9)	θ value	2.42085e-154 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

SO1A4_MOUSE
NC score	0.988100 (rank : 10)	θ value	7.76955e-161 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EP96	Gene names	Slco1a4, Oatp2, Slc21a5
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A4 (Solute carrier family 21 member 5) (Sodium-independent organic anion- transporting polypeptide 2).

SO3A1_MOUSE
NC score	0.975228 (rank : 11)	θ value	3.00075e-104 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

SO3A1_HUMAN
NC score	0.975018 (rank : 12)	θ value	3.91911e-104 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

SO2A1_HUMAN
NC score	0.973686 (rank : 13)	θ value	2.46047e-98 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO2A1_MOUSE
NC score	0.972635 (rank : 14)	θ value	5.48135e-98 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	51	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO2B1_MOUSE
NC score	0.968117 (rank : 15)	θ value	2.72669e-89 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).

SO5A1_HUMAN
NC score	0.968108 (rank : 16)	θ value	4.07447e-85 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	57	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

SO2B1_HUMAN
NC score	0.967245 (rank : 17)	θ value	4.81303e-86 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	O94956, Q9H2Z0, Q9UFU1	Gene names	SLCO2B1, KIAA0880, OATPB, SLC21A9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9) (Organic anion transporter B) (OATP-B) (Organic anion transporter polypeptide-related protein 2) (OATP-RP2) (OATPRP2).

SO4A1_MOUSE
NC score	0.960878 (rank : 18)	θ value	5.69867e-79 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

SO4A1_HUMAN
NC score	0.959976 (rank : 19)	θ value	1.26953e-78 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

RECK_HUMAN
NC score	0.153020 (rank : 20)	θ value	0.0431538 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	189	Shared Neighborhood Hits	25
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
NC score	0.124670 (rank : 21)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	158	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TEFF2_HUMAN
NC score	0.074640 (rank : 22)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	211	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
NC score	0.073127 (rank : 23)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	214	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

FST_MOUSE
NC score	0.059380 (rank : 24)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	146	Shared Neighborhood Hits	20
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ISK3_MOUSE
NC score	0.055372 (rank : 25)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

IPK1_HUMAN
NC score	0.051459 (rank : 26)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

FST_HUMAN
NC score	0.050812 (rank : 27)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	129	Shared Neighborhood Hits	19
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

AGRIN_HUMAN
NC score	0.049773 (rank : 28)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	582	Shared Neighborhood Hits	27
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

IBP7_MOUSE
NC score	0.038078 (rank : 29)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	230	Shared Neighborhood Hits	17
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

PPRB_HUMAN
NC score	0.018863 (rank : 30)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	311	Shared Neighborhood Hits	3
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

VPP2_HUMAN
NC score	0.018686 (rank : 31)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y487	Gene names	ATP6V0A2
Domain Architecture
Description	Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2 (V- ATPase 116 kDa isoform a2) (TJ6).

PPRB_MOUSE
NC score	0.016687 (rank : 32)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	354	Shared Neighborhood Hits	3
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

VPP2_MOUSE
NC score	0.015230 (rank : 33)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P15920, Q3U2X3, Q9JHJ2	Gene names	Atp6v0a2, Atp6n1b, Tj6
Domain Architecture
Description	Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2 (V- ATPase 116 kDa isoform a2) (Immune suppressor factor J6B7).

MOT1_HUMAN
NC score	0.012369 (rank : 34)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P53985, Q9NSJ9	Gene names	SLC16A1, MCT1
Domain Architecture
Description	Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1).

GAS1_MOUSE
NC score	0.011125 (rank : 35)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q01721	Gene names	Gas1, Gas-1
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 1 precursor (GAS-1).

NPT4_HUMAN
NC score	0.004163 (rank : 36)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	O00476	Gene names	SLC17A3, NPT4
Domain Architecture	No domain graphic available
Description	Sodium-dependent phosphate transport protein 4 (Sodium/phosphate cotransporter 4) (Na(+)/PI cotransporter 4) (Solute carrier family 17 member 3).

ZAN_HUMAN
NC score	0.003546 (rank : 37)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	679	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

GTR4_HUMAN
NC score	0.003541 (rank : 38)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	P14672	Gene names	SLC2A4, GLUT4
Domain Architecture
Description	Solute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4, insulin-responsive).

FINC_HUMAN
NC score	0.003389 (rank : 39)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	302	Shared Neighborhood Hits	3
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

CRBB1_HUMAN
NC score	0.003365 (rank : 40)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P53674	Gene names	CRYBB1
Domain Architecture
Description	Beta crystallin B1.

ZAN_MOUSE
NC score	0.003348 (rank : 41)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	808	Shared Neighborhood Hits	11
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

IRK4_HUMAN
NC score	0.001833 (rank : 42)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P48050	Gene names	KCNJ4
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (Hippocampal inward rectifier) (HIR) (HRK1) (HIRK2).

OR8I2_HUMAN
NC score	-0.002584 (rank : 43)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	700	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N0Y5, Q96RC5	Gene names	OR8I2
Domain Architecture
Description	Olfactory receptor 8I2.