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Network neighborhood for query Sequence : SO1B3_HUMAN

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SO1B3_HUMAN
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SO1B1_HUMAN
θ value	0 (rank : 1)	NC score	0.998934 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	43	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

SO1B2_MOUSE
θ value	0 (rank : 2)	NC score	0.998046 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JJL3, Q9JI79, Q9JJJ1	Gene names	Slco1b2, Slc21a10
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B2 (Solute carrier family 21 member 10) (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6).

SO1B3_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

SO1C1_HUMAN
θ value	2.32852e-173 (rank : 4)	NC score	0.991542 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYB5	Gene names	SLCO1C1, OATPF, SLC21A14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5).

SO1C1_MOUSE
θ value	2.17943e-171 (rank : 5)	NC score	0.990993 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

SO1A5_MOUSE
θ value	4.4118e-156 (rank : 6)	NC score	0.985250 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YY5, Q91XS2	Gene names	Slco1a5, Oatp3, Slc21a7
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A5 (Solute carrier family 21 member 7) (Sodium-independent organic anion transporter 3) (Organic anion-transporting polypeptide 3).

SO1A4_MOUSE
θ value	2.34478e-149 (rank : 7)	NC score	0.984622 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EP96	Gene names	Slco1a4, Oatp2, Slc21a5
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A4 (Solute carrier family 21 member 5) (Sodium-independent organic anion- transporting polypeptide 2).

SO1A6_MOUSE
θ value	2.68277e-145 (rank : 8)	NC score	0.984724 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

SO1A1_MOUSE
θ value	2.96616e-144 (rank : 9)	NC score	0.984575 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SO1A2_HUMAN
θ value	1.98959e-140 (rank : 10)	NC score	0.984724 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

SO3A1_MOUSE
θ value	4.1872e-106 (rank : 11)	NC score	0.974341 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

SO3A1_HUMAN
θ value	6.0463e-105 (rank : 12)	NC score	0.974023 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

SO2A1_MOUSE
θ value	1.06975e-93 (rank : 13)	NC score	0.970441 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO2A1_HUMAN
θ value	1.18275e-92 (rank : 14)	NC score	0.970572 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO5A1_HUMAN
θ value	5.6855e-87 (rank : 15)	NC score	0.967947 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	57	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

SO2B1_MOUSE
θ value	7.42547e-87 (rank : 16)	NC score	0.966281 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).

SO2B1_HUMAN
θ value	1.65422e-86 (rank : 17)	NC score	0.965593 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	O94956, Q9H2Z0, Q9UFU1	Gene names	SLCO2B1, KIAA0880, OATPB, SLC21A9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9) (Organic anion transporter B) (OATP-B) (Organic anion transporter polypeptide-related protein 2) (OATP-RP2) (OATPRP2).

SO4A1_HUMAN
θ value	2.73302e-81 (rank : 18)	NC score	0.959704 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	54	Shared Neighborhood Hits	24
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

SO4A1_MOUSE
θ value	8.22888e-78 (rank : 19)	NC score	0.959963 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	35	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

GTR2_HUMAN
θ value	0.0113563 (rank : 20)	NC score	0.030594 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P11168	Gene names	SLC2A2, GLUT2
Domain Architecture
Description	Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver).

RECK_HUMAN
θ value	0.0431538 (rank : 21)	NC score	0.153786 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	189	Shared Neighborhood Hits	27
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	0.21417 (rank : 22)	NC score	0.124378 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	158	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TEFF2_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.084327 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	214	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

EAA1_MOUSE
θ value	0.813845 (rank : 24)	NC score	0.014112 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	P56564, Q99P53	Gene names	Slc1a3, Eaat1, Gmt1
Domain Architecture
Description	Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter) (High-affinity neuronal glutamate transporter) (Glial high affinity glutamate transporter) (GLAST).

AGRIN_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.053111 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	582	Shared Neighborhood Hits	29
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

TEFF2_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.084883 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	211	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

EAA1_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.013052 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	P43003	Gene names	SLC1A3, EAAT1, GLAST1
Domain Architecture
Description	Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (Glial glutamate transporter) (GLAST-1).

NOTC1_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.002147 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	916	Shared Neighborhood Hits	10
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

EI24_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.020175 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	O14681	Gene names	EI24, PIG8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

ASXL1_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.008489 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	260	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

FSTL5_MOUSE
θ value	4.03905 (rank : 31)	NC score	0.014443 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	355	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

FST_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.056961 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	146	Shared Neighborhood Hits	23
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

EAA4_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.010459 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	O35544	Gene names	Slc1a6, Eaat4
Domain Architecture
Description	Excitatory amino acid transporter 4 (Sodium-dependent glutamate/aspartate transporter) (High-affinity neuronal glutamate transporter).

FST_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.049168 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	129	Shared Neighborhood Hits	22
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

O10A5_HUMAN
θ value	6.88961 (rank : 35)	NC score	-0.003204 (rank : 43)
Query Neighborhood Hits	41	Target Neighborhood Hits	767	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H207, Q52M66, Q96R22	Gene names	OR10A5
Domain Architecture
Description	Olfactory receptor 10A5 (HP3) (Olfactory receptor-like protein JCG6).

SUV92_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.005346 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

FSTL1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.022881 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	68	Shared Neighborhood Hits	13
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.023159 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	74	Shared Neighborhood Hits	13
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

NCKX3_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.003535 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HC58, Q9BQJ9, Q9BQL7, Q9BQY3, Q9H519	Gene names	SLC24A3, NCKX3
Domain Architecture
Description	Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3).

NOTC2_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.000861 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	1069	Shared Neighborhood Hits	10
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SUV92_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.004883 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

IPK1_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.052530 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

ISK3_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.056360 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

Hits sorted by NC score

SO1B3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

SO1B1_HUMAN
NC score	0.998934 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	43	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

SO1B2_MOUSE
NC score	0.998046 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JJL3, Q9JI79, Q9JJJ1	Gene names	Slco1b2, Slc21a10
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B2 (Solute carrier family 21 member 10) (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6).

SO1C1_HUMAN
NC score	0.991542 (rank : 4)	θ value	2.32852e-173 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYB5	Gene names	SLCO1C1, OATPF, SLC21A14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5).

SO1C1_MOUSE
NC score	0.990993 (rank : 5)	θ value	2.17943e-171 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

SO1A5_MOUSE
NC score	0.985250 (rank : 6)	θ value	4.4118e-156 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YY5, Q91XS2	Gene names	Slco1a5, Oatp3, Slc21a7
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A5 (Solute carrier family 21 member 7) (Sodium-independent organic anion transporter 3) (Organic anion-transporting polypeptide 3).

SO1A2_HUMAN
NC score	0.984724 (rank : 7)	θ value	1.98959e-140 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

SO1A6_MOUSE
NC score	0.984724 (rank : 8)	θ value	2.68277e-145 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

SO1A4_MOUSE
NC score	0.984622 (rank : 9)	θ value	2.34478e-149 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EP96	Gene names	Slco1a4, Oatp2, Slc21a5
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A4 (Solute carrier family 21 member 5) (Sodium-independent organic anion- transporting polypeptide 2).

SO1A1_MOUSE
NC score	0.984575 (rank : 10)	θ value	2.96616e-144 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SO3A1_MOUSE
NC score	0.974341 (rank : 11)	θ value	4.1872e-106 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

SO3A1_HUMAN
NC score	0.974023 (rank : 12)	θ value	6.0463e-105 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

SO2A1_HUMAN
NC score	0.970572 (rank : 13)	θ value	1.18275e-92 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO2A1_MOUSE
NC score	0.970441 (rank : 14)	θ value	1.06975e-93 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO5A1_HUMAN
NC score	0.967947 (rank : 15)	θ value	5.6855e-87 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	57	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

SO2B1_MOUSE
NC score	0.966281 (rank : 16)	θ value	7.42547e-87 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).

SO2B1_HUMAN
NC score	0.965593 (rank : 17)	θ value	1.65422e-86 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	O94956, Q9H2Z0, Q9UFU1	Gene names	SLCO2B1, KIAA0880, OATPB, SLC21A9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9) (Organic anion transporter B) (OATP-B) (Organic anion transporter polypeptide-related protein 2) (OATP-RP2) (OATPRP2).

SO4A1_MOUSE
NC score	0.959963 (rank : 18)	θ value	8.22888e-78 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	35	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

SO4A1_HUMAN
NC score	0.959704 (rank : 19)	θ value	2.73302e-81 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	54	Shared Neighborhood Hits	24
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

RECK_HUMAN
NC score	0.153786 (rank : 20)	θ value	0.0431538 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	189	Shared Neighborhood Hits	27
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
NC score	0.124378 (rank : 21)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	158	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TEFF2_HUMAN
NC score	0.084883 (rank : 22)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	211	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
NC score	0.084327 (rank : 23)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	214	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

FST_MOUSE
NC score	0.056961 (rank : 24)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	146	Shared Neighborhood Hits	23
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ISK3_MOUSE
NC score	0.056360 (rank : 25)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

AGRIN_HUMAN
NC score	0.053111 (rank : 26)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	582	Shared Neighborhood Hits	29
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

IPK1_HUMAN
NC score	0.052530 (rank : 27)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

FST_HUMAN
NC score	0.049168 (rank : 28)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	129	Shared Neighborhood Hits	22
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GTR2_HUMAN
NC score	0.030594 (rank : 29)	θ value	0.0113563 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P11168	Gene names	SLC2A2, GLUT2
Domain Architecture
Description	Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver).

FSTL1_MOUSE
NC score	0.023159 (rank : 30)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	74	Shared Neighborhood Hits	13
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FSTL1_HUMAN
NC score	0.022881 (rank : 31)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	68	Shared Neighborhood Hits	13
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

EI24_HUMAN
NC score	0.020175 (rank : 32)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	O14681	Gene names	EI24, PIG8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

FSTL5_MOUSE
NC score	0.014443 (rank : 33)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	355	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

EAA1_MOUSE
NC score	0.014112 (rank : 34)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	P56564, Q99P53	Gene names	Slc1a3, Eaat1, Gmt1
Domain Architecture
Description	Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter) (High-affinity neuronal glutamate transporter) (Glial high affinity glutamate transporter) (GLAST).

EAA1_HUMAN
NC score	0.013052 (rank : 35)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	P43003	Gene names	SLC1A3, EAAT1, GLAST1
Domain Architecture
Description	Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (Glial glutamate transporter) (GLAST-1).

EAA4_MOUSE
NC score	0.010459 (rank : 36)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	O35544	Gene names	Slc1a6, Eaat4
Domain Architecture
Description	Excitatory amino acid transporter 4 (Sodium-dependent glutamate/aspartate transporter) (High-affinity neuronal glutamate transporter).

ASXL1_HUMAN
NC score	0.008489 (rank : 37)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	260	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

SUV92_HUMAN
NC score	0.005346 (rank : 38)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_MOUSE
NC score	0.004883 (rank : 39)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

NCKX3_HUMAN
NC score	0.003535 (rank : 40)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HC58, Q9BQJ9, Q9BQL7, Q9BQY3, Q9H519	Gene names	SLC24A3, NCKX3
Domain Architecture
Description	Sodium/potassium/calcium exchanger 3 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 3) (Solute carrier family 24 member 3).

NOTC1_MOUSE
NC score	0.002147 (rank : 41)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	916	Shared Neighborhood Hits	10
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
NC score	0.000861 (rank : 42)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	1069	Shared Neighborhood Hits	10
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

O10A5_HUMAN
NC score	-0.003204 (rank : 43)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	767	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H207, Q52M66, Q96R22	Gene names	OR10A5
Domain Architecture
Description	Olfactory receptor 10A5 (HP3) (Olfactory receptor-like protein JCG6).