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Network neighborhood for query Sequence : EAA4_MOUSE

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EAA4_MOUSE
SwissProt Accessions	O35544	Gene names	Slc1a6, Eaat4
Domain Architecture
Description	Excitatory amino acid transporter 4 (Sodium-dependent glutamate/aspartate transporter) (High-affinity neuronal glutamate transporter).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EAA1_HUMAN
θ value	0 (rank : 1)	NC score	0.997235 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	P43003	Gene names	SLC1A3, EAAT1, GLAST1
Domain Architecture
Description	Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (Glial glutamate transporter) (GLAST-1).

EAA1_MOUSE
θ value	0 (rank : 2)	NC score	0.997140 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	P56564, Q99P53	Gene names	Slc1a3, Eaat1, Gmt1
Domain Architecture
Description	Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter) (High-affinity neuronal glutamate transporter) (Glial high affinity glutamate transporter) (GLAST).

EAA4_HUMAN
θ value	0 (rank : 3)	NC score	0.999754 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	P48664	Gene names	SLC1A6, EAAT4
Domain Architecture
Description	Excitatory amino acid transporter 4 (Sodium-dependent glutamate/aspartate transporter).

EAA4_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	O35544	Gene names	Slc1a6, Eaat4
Domain Architecture
Description	Excitatory amino acid transporter 4 (Sodium-dependent glutamate/aspartate transporter) (High-affinity neuronal glutamate transporter).

EAA5_HUMAN
θ value	3.5201e-129 (rank : 5)	NC score	0.991527 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	O00341	Gene names	SLC1A7, EAAT5
Domain Architecture
Description	Excitatory amino acid transporter 5 (Retinal glutamate transporter).

EAA3_MOUSE
θ value	6.00439e-129 (rank : 6)	NC score	0.989234 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	P51906, O35869, O35875	Gene names	Slc1a1, Eaac1, Eaat3
Domain Architecture
Description	Excitatory amino acid transporter 3 (Sodium-dependent glutamate/aspartate transporter 3) (Excitatory amino-acid carrier 1).

EAA3_HUMAN
θ value	3.89193e-128 (rank : 7)	NC score	0.988948 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	P43005, O75587, Q5VZ24, Q8N199, Q9UEW2	Gene names	SLC1A1, EAAC1, EAAT3
Domain Architecture
Description	Excitatory amino acid transporter 3 (Sodium-dependent glutamate/aspartate transporter 3) (Excitatory amino-acid carrier 1) (Neuronal and epithelial glutamate transporter).

EAA2_HUMAN
θ value	1.0968e-122 (rank : 8)	NC score	0.986301 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	13
SwissProt Accessions	P43004, Q14417	Gene names	SLC1A2, EAAT2, GLT1
Domain Architecture
Description	Excitatory amino acid transporter 2 (Sodium-dependent glutamate/aspartate transporter 2).

EAA2_MOUSE
θ value	2.70151e-121 (rank : 9)	NC score	0.986261 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P43006, O35877, O54686, O54687	Gene names	Slc1a2, Eaat2, Glt1
Domain Architecture
Description	Excitatory amino acid transporter 2 (Sodium-dependent glutamate/aspartate transporter 2) (GLT-1).

SATT_HUMAN
θ value	6.45994e-107 (rank : 10)	NC score	0.984095 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	P43007	Gene names	SLC1A4, ASCT1, SATT
Domain Architecture
Description	Neutral amino acid transporter A (SATT) (Alanine/serine/cysteine/ threonine transporter) (ASCT1).

SATT_MOUSE
θ value	6.0463e-105 (rank : 11)	NC score	0.984032 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	13
SwissProt Accessions	O35874	Gene names	Slc1a4, Asct1
Domain Architecture
Description	Neutral amino acid transporter A (SATT) (Alanine/serine/cysteine/ threonine transporter) (ASCT1).

AAAT_HUMAN
θ value	6.06035e-97 (rank : 12)	NC score	0.980592 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	Q15758, O95720, Q96RL9, Q9BWQ3, Q9UNP2	Gene names	SLC1A5, ASCT2, M7V1, RDR, RDRC
Domain Architecture
Description	Neutral amino acid transporter B(0) (ATB(0)) (Sodium-dependent neutral amino acid transporter type 2) (RD114/simian type D retrovirus receptor) (Baboon M7 virus receptor).

AAAT_MOUSE
θ value	7.40825e-95 (rank : 13)	NC score	0.978751 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	P51912, Q61326	Gene names	Slc1a5, Aaat, Asct2, Slc1a7
Domain Architecture
Description	Neutral amino acid transporter B (Insulin-activated amino acid transporter) (ASC-like Na(+)-dependent neutral amino acid transporter ASCT2).

BRD8_MOUSE
θ value	2.36792 (rank : 14)	NC score	0.012813 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	422	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

ADRB3_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.000700 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	900	Shared Neighborhood Hits	3
SwissProt Accessions	P13945, Q4JFT4	Gene names	ADRB3, ADRB3R, B3AR
Domain Architecture
Description	Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3 adrenoreceptor).

BRD8_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.011073 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

HES2_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.012825 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

RM11_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.018144 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3B7, Q96Q73	Gene names	MRPL11
Domain Architecture
Description	39S ribosomal protein L11, mitochondrial precursor (L11mt) (MRP-L11).

S12A3_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.004143 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P59158	Gene names	Slc12a3, Tsc
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

SO1B3_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.010459 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

UTRO_HUMAN
θ value	8.99809 (rank : 21)	NC score	-0.000134 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	960	Shared Neighborhood Hits	2
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

Hits sorted by NC score

EAA4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	O35544	Gene names	Slc1a6, Eaat4
Domain Architecture
Description	Excitatory amino acid transporter 4 (Sodium-dependent glutamate/aspartate transporter) (High-affinity neuronal glutamate transporter).

EAA4_HUMAN
NC score	0.999754 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	P48664	Gene names	SLC1A6, EAAT4
Domain Architecture
Description	Excitatory amino acid transporter 4 (Sodium-dependent glutamate/aspartate transporter).

EAA1_HUMAN
NC score	0.997235 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	P43003	Gene names	SLC1A3, EAAT1, GLAST1
Domain Architecture
Description	Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (Glial glutamate transporter) (GLAST-1).

EAA1_MOUSE
NC score	0.997140 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	P56564, Q99P53	Gene names	Slc1a3, Eaat1, Gmt1
Domain Architecture
Description	Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter) (High-affinity neuronal glutamate transporter) (Glial high affinity glutamate transporter) (GLAST).

EAA5_HUMAN
NC score	0.991527 (rank : 5)	θ value	3.5201e-129 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	O00341	Gene names	SLC1A7, EAAT5
Domain Architecture
Description	Excitatory amino acid transporter 5 (Retinal glutamate transporter).

EAA3_MOUSE
NC score	0.989234 (rank : 6)	θ value	6.00439e-129 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	P51906, O35869, O35875	Gene names	Slc1a1, Eaac1, Eaat3
Domain Architecture
Description	Excitatory amino acid transporter 3 (Sodium-dependent glutamate/aspartate transporter 3) (Excitatory amino-acid carrier 1).

EAA3_HUMAN
NC score	0.988948 (rank : 7)	θ value	3.89193e-128 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	P43005, O75587, Q5VZ24, Q8N199, Q9UEW2	Gene names	SLC1A1, EAAC1, EAAT3
Domain Architecture
Description	Excitatory amino acid transporter 3 (Sodium-dependent glutamate/aspartate transporter 3) (Excitatory amino-acid carrier 1) (Neuronal and epithelial glutamate transporter).

EAA2_HUMAN
NC score	0.986301 (rank : 8)	θ value	1.0968e-122 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	13
SwissProt Accessions	P43004, Q14417	Gene names	SLC1A2, EAAT2, GLT1
Domain Architecture
Description	Excitatory amino acid transporter 2 (Sodium-dependent glutamate/aspartate transporter 2).

EAA2_MOUSE
NC score	0.986261 (rank : 9)	θ value	2.70151e-121 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P43006, O35877, O54686, O54687	Gene names	Slc1a2, Eaat2, Glt1
Domain Architecture
Description	Excitatory amino acid transporter 2 (Sodium-dependent glutamate/aspartate transporter 2) (GLT-1).

SATT_HUMAN
NC score	0.984095 (rank : 10)	θ value	6.45994e-107 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	P43007	Gene names	SLC1A4, ASCT1, SATT
Domain Architecture
Description	Neutral amino acid transporter A (SATT) (Alanine/serine/cysteine/ threonine transporter) (ASCT1).

SATT_MOUSE
NC score	0.984032 (rank : 11)	θ value	6.0463e-105 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	13
SwissProt Accessions	O35874	Gene names	Slc1a4, Asct1
Domain Architecture
Description	Neutral amino acid transporter A (SATT) (Alanine/serine/cysteine/ threonine transporter) (ASCT1).

AAAT_HUMAN
NC score	0.980592 (rank : 12)	θ value	6.06035e-97 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	Q15758, O95720, Q96RL9, Q9BWQ3, Q9UNP2	Gene names	SLC1A5, ASCT2, M7V1, RDR, RDRC
Domain Architecture
Description	Neutral amino acid transporter B(0) (ATB(0)) (Sodium-dependent neutral amino acid transporter type 2) (RD114/simian type D retrovirus receptor) (Baboon M7 virus receptor).

AAAT_MOUSE
NC score	0.978751 (rank : 13)	θ value	7.40825e-95 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	P51912, Q61326	Gene names	Slc1a5, Aaat, Asct2, Slc1a7
Domain Architecture
Description	Neutral amino acid transporter B (Insulin-activated amino acid transporter) (ASC-like Na(+)-dependent neutral amino acid transporter ASCT2).

RM11_HUMAN
NC score	0.018144 (rank : 14)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3B7, Q96Q73	Gene names	MRPL11
Domain Architecture
Description	39S ribosomal protein L11, mitochondrial precursor (L11mt) (MRP-L11).

HES2_MOUSE
NC score	0.012825 (rank : 15)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O54792	Gene names	Hes2
Domain Architecture
Description	Transcription factor HES-2 (Hairy and enhancer of split 2).

BRD8_MOUSE
NC score	0.012813 (rank : 16)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	422	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRD8_HUMAN
NC score	0.011073 (rank : 17)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

SO1B3_HUMAN
NC score	0.010459 (rank : 18)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

S12A3_MOUSE
NC score	0.004143 (rank : 19)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P59158	Gene names	Slc12a3, Tsc
Domain Architecture
Description	Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter).

ADRB3_HUMAN
NC score	0.000700 (rank : 20)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	900	Shared Neighborhood Hits	3
SwissProt Accessions	P13945, Q4JFT4	Gene names	ADRB3, ADRB3R, B3AR
Domain Architecture
Description	Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3 adrenoreceptor).

UTRO_HUMAN
NC score	-0.000134 (rank : 21)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	960	Shared Neighborhood Hits	2
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).