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Network neighborhood for query Sequence : ISK5_HUMAN

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ISK5_HUMAN
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ISK5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

AGRIN_HUMAN
θ value	4.16044e-13 (rank : 2)	NC score	0.216150 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	582	Shared Neighborhood Hits	48
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ISK6_MOUSE
θ value	2.61198e-07 (rank : 3)	NC score	0.540270 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	37	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

IPK1_HUMAN
θ value	3.77169e-06 (rank : 4)	NC score	0.554793 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

ISK6_HUMAN
θ value	3.77169e-06 (rank : 5)	NC score	0.528353 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	32	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

FST_MOUSE
θ value	8.40245e-06 (rank : 6)	NC score	0.363140 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	146	Shared Neighborhood Hits	43
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ISK3_MOUSE
θ value	8.40245e-06 (rank : 7)	NC score	0.527975 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

ISK4_MOUSE
θ value	5.44631e-05 (rank : 8)	NC score	0.486165 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	28	Shared Neighborhood Hits	27
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

TEFF2_HUMAN
θ value	0.00020696 (rank : 9)	NC score	0.300037 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	211	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	0.000270298 (rank : 10)	NC score	0.297296 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	214	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

IPK2_MOUSE
θ value	0.00035302 (rank : 11)	NC score	0.455618 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	26	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BMY7	Gene names	Spink2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 2 precursor.

ISK4_HUMAN
θ value	0.00035302 (rank : 12)	NC score	0.481143 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

ISK7_HUMAN
θ value	0.000602161 (rank : 13)	NC score	0.455036 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	31	Shared Neighborhood Hits	28
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

FSTL1_HUMAN
θ value	0.00102713 (rank : 14)	NC score	0.338866 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
θ value	0.00102713 (rank : 15)	NC score	0.336552 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	74	Shared Neighborhood Hits	38
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

TARA_HUMAN
θ value	0.00102713 (rank : 16)	NC score	0.060269 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	1626	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

FST_HUMAN
θ value	0.00134147 (rank : 17)	NC score	0.344107 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

IPK2_HUMAN
θ value	0.00390308 (rank : 18)	NC score	0.459405 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

TICN3_HUMAN
θ value	0.00390308 (rank : 19)	NC score	0.230326 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_MOUSE
θ value	0.00665767 (rank : 20)	NC score	0.231905 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

ISK7_MOUSE
θ value	0.00869519 (rank : 21)	NC score	0.410744 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

RRBP1_MOUSE
θ value	0.0113563 (rank : 22)	NC score	0.036336 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	1650	Shared Neighborhood Hits	20
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RECK_HUMAN
θ value	0.0736092 (rank : 23)	NC score	0.150503 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	189	Shared Neighborhood Hits	28
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	0.163984 (rank : 24)	NC score	0.142744 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	158	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TICN2_HUMAN
θ value	0.163984 (rank : 25)	NC score	0.201467 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

HTRA4_HUMAN
θ value	0.21417 (rank : 26)	NC score	0.093647 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	119	Shared Neighborhood Hits	16
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

TICN2_MOUSE
θ value	0.21417 (rank : 27)	NC score	0.202846 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

ADA32_MOUSE
θ value	0.279714 (rank : 28)	NC score	0.022761 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	219	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

KMHN1_MOUSE
θ value	0.365318 (rank : 29)	NC score	0.025252 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	949	Shared Neighborhood Hits	9
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

SPRL1_HUMAN
θ value	0.47712 (rank : 30)	NC score	0.178717 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	231	Shared Neighborhood Hits	35
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

FSTL3_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.261070 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	162	Shared Neighborhood Hits	41
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL4_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.125537 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	344	Shared Neighborhood Hits	36
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL5_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.124248 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	347	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.119971 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	355	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

HTRA3_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.094151 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	152	Shared Neighborhood Hits	26
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

NR2E1_MOUSE
θ value	0.62314 (rank : 36)	NC score	0.031060 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

PARP1_MOUSE
θ value	0.62314 (rank : 37)	NC score	0.039680 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

TICN1_MOUSE
θ value	0.62314 (rank : 38)	NC score	0.191933 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	79	Shared Neighborhood Hits	35
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

ZN394_HUMAN
θ value	0.62314 (rank : 39)	NC score	0.007349 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	752	Shared Neighborhood Hits	9
SwissProt Accessions	Q53GI3, Q6P5X9, Q8TB27, Q9HA37	Gene names	ZNF394
Domain Architecture	No domain graphic available
Description	Zinc finger protein 394.

ZN668_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.007694 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	761	Shared Neighborhood Hits	8
SwissProt Accessions	Q96K58, Q59EV1, Q8N669, Q9H8L4	Gene names	ZNF668
Domain Architecture	No domain graphic available
Description	Zinc finger protein 668.

ZN668_MOUSE
θ value	0.62314 (rank : 41)	NC score	0.007713 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	763	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K2R5, Q3TEM2, Q3U7Y5, Q8C8B7	Gene names	Znf668, Zfp668
Domain Architecture	No domain graphic available
Description	Zinc finger protein 668.

NIPBL_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.035655 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	1311	Shared Neighborhood Hits	18
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NR2E1_HUMAN
θ value	0.813845 (rank : 43)	NC score	0.030792 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

PTN12_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.016693 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

TNR9_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.038256 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	166	Shared Neighborhood Hits	2
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

FA76B_MOUSE
θ value	1.06291 (rank : 46)	NC score	0.052033 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

ITB1_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.028358 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

TICN1_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.180001 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

CENPF_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.015850 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	1932	Shared Neighborhood Hits	16
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

SPRL1_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.150113 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	403	Shared Neighborhood Hits	30
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

CCD21_MOUSE
θ value	1.81305 (rank : 51)	NC score	0.020987 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

FA76B_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.048547 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	184	Shared Neighborhood Hits	5
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

SMOC2_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.121098 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	81	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

FSTL3_MOUSE
θ value	2.36792 (rank : 54)	NC score	0.250376 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	152	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL4_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.121953 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	333	Shared Neighborhood Hits	37
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

RARA_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.025011 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARB_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.024911 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

SETX_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.035075 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SO5A1_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.038347 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	57	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

HTRA3_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.077687 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

RARB_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.024483 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

ITB1_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.025512 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	283	Shared Neighborhood Hits	7
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

IWS1_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.019414 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	1258	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LRRF2_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.017635 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	791	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

PHF3_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.027664 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	419	Shared Neighborhood Hits	6
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

SO4A1_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.028806 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	35	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

SPRC_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.159954 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.157906 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	46	Shared Neighborhood Hits	22
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

HTRA1_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.084972 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	140	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

MEFV_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.007108 (rank : 90)
Query Neighborhood Hits	89	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

SNPC4_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.017057 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	589	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

ZN260_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.004178 (rank : 94)
Query Neighborhood Hits	89	Target Neighborhood Hits	765	Shared Neighborhood Hits	8
SwissProt Accessions	Q62513, Q3U170, Q8C2Q6, Q9R2B4	Gene names	Znf260, Zfp260
Domain Architecture	No domain graphic available
Description	Zinc finger protein 260 (Zfp-260).

CI039_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.014642 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	1171	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

IBP7_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.080837 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	220	Shared Neighborhood Hits	24
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

LIPR1_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.011630 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q5BKQ4, O70478, Q6NV82	Gene names	Pnliprp1
Domain Architecture	No domain graphic available
Description	Pancreatic lipase-related protein 1 precursor (EC 3.1.1.3).

MINT_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.018241 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	1291	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NKTR_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.018257 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	658	Shared Neighborhood Hits	11
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RARA_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.022664 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

UBP34_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.011343 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	189	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

ZN711_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.005604 (rank : 91)
Query Neighborhood Hits	89	Target Neighborhood Hits	751	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y462, Q6NX42, Q9Y4J6	Gene names	ZNF711, CMPX1, ZNF6
Domain Architecture
Description	Zinc finger protein 711 (Zinc finger protein 6).

1B53_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.000837 (rank : 95)
Query Neighborhood Hits	89	Target Neighborhood Hits	212	Shared Neighborhood Hits	2
SwissProt Accessions	P30491, O78053, O78138, Q30198, Q9BD43, Q9GJF0, Q9MY42, Q9TP36, Q9TQH8	Gene names	HLA-B, HLAB
Domain Architecture
Description	HLA class I histocompatibility antigen, B-53 alpha chain precursor (MHC class I antigen B*53) (Bw-53).

ADA2B_HUMAN
θ value	8.99809 (rank : 82)	NC score	-0.000649 (rank : 96)
Query Neighborhood Hits	89	Target Neighborhood Hits	881	Shared Neighborhood Hits	2
SwissProt Accessions	P18089, Q4TUH9, Q53RF2, Q9BZK0	Gene names	ADRA2B
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor) (Alpha-2 adrenergic receptor subtype C2).

APBB2_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.013165 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

NOL7_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.023317 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7Z3, Q9CY79, Q9JJE2	Gene names	Nol7
Domain Architecture	No domain graphic available
Description	Nucleolar protein 7.

PDE1C_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.008708 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

SO1A6_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.019890 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

ZFP38_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.004227 (rank : 93)
Query Neighborhood Hits	89	Target Neighborhood Hits	768	Shared Neighborhood Hits	10
SwissProt Accessions	Q07231	Gene names	Znf38, Zfp-38, Zfp38, Zipro1
Domain Architecture
Description	Zinc finger protein 38 (Zfp-38) (CtFIN51) (Transcription factor RU49).

ZFY1_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.005177 (rank : 92)
Query Neighborhood Hits	89	Target Neighborhood Hits	790	Shared Neighborhood Hits	8
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

ZRF1_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.014866 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	414	Shared Neighborhood Hits	7
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

HTRA1_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.075941 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	155	Shared Neighborhood Hits	28
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

IBP7_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.072457 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	230	Shared Neighborhood Hits	23
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

KAZD1_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.089658 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	248	Shared Neighborhood Hits	30
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.082972 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	281	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

SMOC1_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.103862 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	81	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC1_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.107114 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	74	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

SMOC2_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.104052 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

Hits sorted by NC score

ISK5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

IPK1_HUMAN
NC score	0.554793 (rank : 2)	θ value	3.77169e-06 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

ISK6_MOUSE
NC score	0.540270 (rank : 3)	θ value	2.61198e-07 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	37	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

ISK6_HUMAN
NC score	0.528353 (rank : 4)	θ value	3.77169e-06 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	32	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

ISK3_MOUSE
NC score	0.527975 (rank : 5)	θ value	8.40245e-06 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

ISK4_MOUSE
NC score	0.486165 (rank : 6)	θ value	5.44631e-05 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	28	Shared Neighborhood Hits	27
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

ISK4_HUMAN
NC score	0.481143 (rank : 7)	θ value	0.00035302 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

IPK2_HUMAN
NC score	0.459405 (rank : 8)	θ value	0.00390308 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

IPK2_MOUSE
NC score	0.455618 (rank : 9)	θ value	0.00035302 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	26	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BMY7	Gene names	Spink2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 2 precursor.

ISK7_HUMAN
NC score	0.455036 (rank : 10)	θ value	0.000602161 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	31	Shared Neighborhood Hits	28
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

ISK7_MOUSE
NC score	0.410744 (rank : 11)	θ value	0.00869519 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	28	Shared Neighborhood Hits	28
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

FST_MOUSE
NC score	0.363140 (rank : 12)	θ value	8.40245e-06 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	146	Shared Neighborhood Hits	43
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_HUMAN
NC score	0.344107 (rank : 13)	θ value	0.00134147 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FSTL1_HUMAN
NC score	0.338866 (rank : 14)	θ value	0.00102713 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
NC score	0.336552 (rank : 15)	θ value	0.00102713 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	74	Shared Neighborhood Hits	38
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

TEFF2_HUMAN
NC score	0.300037 (rank : 16)	θ value	0.00020696 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	211	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
NC score	0.297296 (rank : 17)	θ value	0.000270298 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	214	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

FSTL3_HUMAN
NC score	0.261070 (rank : 18)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	162	Shared Neighborhood Hits	41
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
NC score	0.250376 (rank : 19)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	152	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

TICN3_MOUSE
NC score	0.231905 (rank : 20)	θ value	0.00665767 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	83	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_HUMAN
NC score	0.230326 (rank : 21)	θ value	0.00390308 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

AGRIN_HUMAN
NC score	0.216150 (rank : 22)	θ value	4.16044e-13 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	582	Shared Neighborhood Hits	48
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

TICN2_MOUSE
NC score	0.202846 (rank : 23)	θ value	0.21417 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_HUMAN
NC score	0.201467 (rank : 24)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN1_MOUSE
NC score	0.191933 (rank : 25)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	79	Shared Neighborhood Hits	35
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_HUMAN
NC score	0.180001 (rank : 26)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

SPRL1_HUMAN
NC score	0.178717 (rank : 27)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	231	Shared Neighborhood Hits	35
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SPRC_HUMAN
NC score	0.159954 (rank : 28)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
NC score	0.157906 (rank : 29)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	46	Shared Neighborhood Hits	22
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

RECK_HUMAN
NC score	0.150503 (rank : 30)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	189	Shared Neighborhood Hits	28
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

SPRL1_MOUSE
NC score	0.150113 (rank : 31)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	403	Shared Neighborhood Hits	30
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

RECK_MOUSE
NC score	0.142744 (rank : 32)	θ value	0.163984 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	158	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

FSTL4_HUMAN
NC score	0.125537 (rank : 33)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	344	Shared Neighborhood Hits	36
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL5_HUMAN
NC score	0.124248 (rank : 34)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	347	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL4_MOUSE
NC score	0.121953 (rank : 35)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	333	Shared Neighborhood Hits	37
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

SMOC2_MOUSE
NC score	0.121098 (rank : 36)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	81	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

FSTL5_MOUSE
NC score	0.119971 (rank : 37)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	355	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

SMOC1_MOUSE
NC score	0.107114 (rank : 38)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	89	Target Neighborhood Hits	74	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

SMOC2_HUMAN
NC score	0.104052 (rank : 39)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	89	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC1_HUMAN
NC score	0.103862 (rank : 40)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	89	Target Neighborhood Hits	81	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

HTRA3_HUMAN
NC score	0.094151 (rank : 41)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	152	Shared Neighborhood Hits	26
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA4_HUMAN
NC score	0.093647 (rank : 42)	θ value	0.21417 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	119	Shared Neighborhood Hits	16
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

KAZD1_HUMAN
NC score	0.089658 (rank : 43)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	89	Target Neighborhood Hits	248	Shared Neighborhood Hits	30
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

HTRA1_MOUSE
NC score	0.084972 (rank : 44)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	140	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

KAZD1_MOUSE
NC score	0.082972 (rank : 45)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	89	Target Neighborhood Hits	281	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

IBP7_HUMAN
NC score	0.080837 (rank : 46)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	220	Shared Neighborhood Hits	24
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

HTRA3_MOUSE
NC score	0.077687 (rank : 47)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HTRA1_HUMAN
NC score	0.075941 (rank : 48)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	89	Target Neighborhood Hits	155	Shared Neighborhood Hits	28
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

IBP7_MOUSE
NC score	0.072457 (rank : 49)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	89	Target Neighborhood Hits	230	Shared Neighborhood Hits	23
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

TARA_HUMAN
NC score	0.060269 (rank : 50)	θ value	0.00102713 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	1626	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

FA76B_MOUSE
NC score	0.052033 (rank : 51)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

FA76B_HUMAN
NC score	0.048547 (rank : 52)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	184	Shared Neighborhood Hits	5
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

PARP1_MOUSE
NC score	0.039680 (rank : 53)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

SO5A1_HUMAN
NC score	0.038347 (rank : 54)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	57	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

TNR9_HUMAN
NC score	0.038256 (rank : 55)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	166	Shared Neighborhood Hits	2
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

RRBP1_MOUSE
NC score	0.036336 (rank : 56)	θ value	0.0113563 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	1650	Shared Neighborhood Hits	20
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

NIPBL_HUMAN
NC score	0.035655 (rank : 57)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	1311	Shared Neighborhood Hits	18
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SETX_HUMAN
NC score	0.035075 (rank : 58)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

NR2E1_MOUSE
NC score	0.031060 (rank : 59)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

NR2E1_HUMAN
NC score	0.030792 (rank : 60)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

SO4A1_MOUSE
NC score	0.028806 (rank : 61)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	35	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

ITB1_HUMAN
NC score	0.028358 (rank : 62)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

PHF3_HUMAN
NC score	0.027664 (rank : 63)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	419	Shared Neighborhood Hits	6
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

ITB1_MOUSE
NC score	0.025512 (rank : 64)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	283	Shared Neighborhood Hits	7
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KMHN1_MOUSE
NC score	0.025252 (rank : 65)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	949	Shared Neighborhood Hits	9
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

RARA_MOUSE
NC score	0.025011 (rank : 66)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARB_MOUSE
NC score	0.024911 (rank : 67)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

RARB_HUMAN
NC score	0.024483 (rank : 68)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

NOL7_MOUSE
NC score	0.023317 (rank : 69)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7Z3, Q9CY79, Q9JJE2	Gene names	Nol7
Domain Architecture	No domain graphic available
Description	Nucleolar protein 7.

ADA32_MOUSE
NC score	0.022761 (rank : 70)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	219	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

RARA_HUMAN
NC score	0.022664 (rank : 71)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

CCD21_MOUSE
NC score	0.020987 (rank : 72)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

SO1A6_MOUSE
NC score	0.019890 (rank : 73)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

IWS1_MOUSE
NC score	0.019414 (rank : 74)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	1258	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NKTR_HUMAN
NC score	0.018257 (rank : 75)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	658	Shared Neighborhood Hits	11
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

MINT_HUMAN
NC score	0.018241 (rank : 76)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	1291	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

LRRF2_HUMAN
NC score	0.017635 (rank : 77)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	791	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

SNPC4_HUMAN
NC score	0.017057 (rank : 78)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	589	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

PTN12_HUMAN
NC score	0.016693 (rank : 79)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

CENPF_HUMAN
NC score	0.015850 (rank : 80)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	1932	Shared Neighborhood Hits	16
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

ZRF1_MOUSE
NC score	0.014866 (rank : 81)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	414	Shared Neighborhood Hits	7
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

CI039_HUMAN
NC score	0.014642 (rank : 82)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	1171	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

APBB2_HUMAN
NC score	0.013165 (rank : 83)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

LIPR1_MOUSE
NC score	0.011630 (rank : 84)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q5BKQ4, O70478, Q6NV82	Gene names	Pnliprp1
Domain Architecture	No domain graphic available
Description	Pancreatic lipase-related protein 1 precursor (EC 3.1.1.3).

UBP34_MOUSE
NC score	0.011343 (rank : 85)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	189	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

PDE1C_MOUSE
NC score	0.008708 (rank : 86)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

ZN668_MOUSE
NC score	0.007713 (rank : 87)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	763	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K2R5, Q3TEM2, Q3U7Y5, Q8C8B7	Gene names	Znf668, Zfp668
Domain Architecture	No domain graphic available
Description	Zinc finger protein 668.

ZN668_HUMAN
NC score	0.007694 (rank : 88)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	761	Shared Neighborhood Hits	8
SwissProt Accessions	Q96K58, Q59EV1, Q8N669, Q9H8L4	Gene names	ZNF668
Domain Architecture	No domain graphic available
Description	Zinc finger protein 668.

ZN394_HUMAN
NC score	0.007349 (rank : 89)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	752	Shared Neighborhood Hits	9
SwissProt Accessions	Q53GI3, Q6P5X9, Q8TB27, Q9HA37	Gene names	ZNF394
Domain Architecture	No domain graphic available
Description	Zinc finger protein 394.

MEFV_HUMAN
NC score	0.007108 (rank : 90)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

ZN711_HUMAN
NC score	0.005604 (rank : 91)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	751	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y462, Q6NX42, Q9Y4J6	Gene names	ZNF711, CMPX1, ZNF6
Domain Architecture
Description	Zinc finger protein 711 (Zinc finger protein 6).

ZFY1_MOUSE
NC score	0.005177 (rank : 92)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	790	Shared Neighborhood Hits	8
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

ZFP38_MOUSE
NC score	0.004227 (rank : 93)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	768	Shared Neighborhood Hits	10
SwissProt Accessions	Q07231	Gene names	Znf38, Zfp-38, Zfp38, Zipro1
Domain Architecture
Description	Zinc finger protein 38 (Zfp-38) (CtFIN51) (Transcription factor RU49).

ZN260_MOUSE
NC score	0.004178 (rank : 94)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	765	Shared Neighborhood Hits	8
SwissProt Accessions	Q62513, Q3U170, Q8C2Q6, Q9R2B4	Gene names	Znf260, Zfp260
Domain Architecture	No domain graphic available
Description	Zinc finger protein 260 (Zfp-260).

1B53_HUMAN
NC score	0.000837 (rank : 95)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	212	Shared Neighborhood Hits	2
SwissProt Accessions	P30491, O78053, O78138, Q30198, Q9BD43, Q9GJF0, Q9MY42, Q9TP36, Q9TQH8	Gene names	HLA-B, HLAB
Domain Architecture
Description	HLA class I histocompatibility antigen, B-53 alpha chain precursor (MHC class I antigen B*53) (Bw-53).

ADA2B_HUMAN
NC score	-0.000649 (rank : 96)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	881	Shared Neighborhood Hits	2
SwissProt Accessions	P18089, Q4TUH9, Q53RF2, Q9BZK0	Gene names	ADRA2B
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor) (Alpha-2 adrenergic receptor subtype C2).