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Network neighborhood for query Sequence : KAZD1_MOUSE

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KAZD1_MOUSE
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KAZD1_MOUSE
θ value	5.55514e-167 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	281	Target Neighborhood Hits	281	Shared Neighborhood Hits	281
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KAZD1_HUMAN
θ value	1.05497e-141 (rank : 2)	NC score	0.980104 (rank : 2)
Query Neighborhood Hits	281	Target Neighborhood Hits	248	Shared Neighborhood Hits	230
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

IBP7_HUMAN
θ value	2.04573e-44 (rank : 3)	NC score	0.875641 (rank : 3)
Query Neighborhood Hits	281	Target Neighborhood Hits	220	Shared Neighborhood Hits	187
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IBP7_MOUSE
θ value	1.01529e-43 (rank : 4)	NC score	0.871216 (rank : 4)
Query Neighborhood Hits	281	Target Neighborhood Hits	230	Shared Neighborhood Hits	186
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

HTRA1_MOUSE
θ value	1.92812e-18 (rank : 5)	NC score	0.449320 (rank : 102)
Query Neighborhood Hits	281	Target Neighborhood Hits	140	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

HTRA1_HUMAN
θ value	6.20254e-17 (rank : 6)	NC score	0.438312 (rank : 107)
Query Neighborhood Hits	281	Target Neighborhood Hits	155	Shared Neighborhood Hits	55
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HTRA3_HUMAN
θ value	4.16044e-13 (rank : 7)	NC score	0.399577 (rank : 138)
Query Neighborhood Hits	281	Target Neighborhood Hits	152	Shared Neighborhood Hits	52
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
θ value	1.2105e-12 (rank : 8)	NC score	0.400929 (rank : 137)
Query Neighborhood Hits	281	Target Neighborhood Hits	156	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

NEO1_HUMAN
θ value	1.133e-10 (rank : 9)	NC score	0.589174 (rank : 18)
Query Neighborhood Hits	281	Target Neighborhood Hits	530	Shared Neighborhood Hits	198
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	1.47974e-10 (rank : 10)	NC score	0.593017 (rank : 15)
Query Neighborhood Hits	281	Target Neighborhood Hits	523	Shared Neighborhood Hits	199
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

OBSL1_HUMAN
θ value	3.29651e-10 (rank : 11)	NC score	0.651657 (rank : 5)
Query Neighborhood Hits	281	Target Neighborhood Hits	354	Shared Neighborhood Hits	199
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

DCC_MOUSE
θ value	6.21693e-09 (rank : 12)	NC score	0.583801 (rank : 22)
Query Neighborhood Hits	281	Target Neighborhood Hits	896	Shared Neighborhood Hits	203
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DCC_HUMAN
θ value	8.11959e-09 (rank : 13)	NC score	0.592969 (rank : 16)
Query Neighborhood Hits	281	Target Neighborhood Hits	583	Shared Neighborhood Hits	203
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

OBSCN_HUMAN
θ value	8.11959e-09 (rank : 14)	NC score	0.305501 (rank : 168)
Query Neighborhood Hits	281	Target Neighborhood Hits	1931	Shared Neighborhood Hits	206
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ROBO2_HUMAN
θ value	3.08544e-08 (rank : 15)	NC score	0.612272 (rank : 7)
Query Neighborhood Hits	281	Target Neighborhood Hits	479	Shared Neighborhood Hits	200
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

DSCL1_HUMAN
θ value	8.97725e-08 (rank : 16)	NC score	0.583461 (rank : 23)
Query Neighborhood Hits	281	Target Neighborhood Hits	589	Shared Neighborhood Hits	207
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

ROBO1_HUMAN
θ value	1.17247e-07 (rank : 17)	NC score	0.611825 (rank : 8)
Query Neighborhood Hits	281	Target Neighborhood Hits	529	Shared Neighborhood Hits	201
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

ROBO1_MOUSE
θ value	1.17247e-07 (rank : 18)	NC score	0.609795 (rank : 12)
Query Neighborhood Hits	281	Target Neighborhood Hits	559	Shared Neighborhood Hits	201
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

ROBO3_MOUSE
θ value	1.17247e-07 (rank : 19)	NC score	0.610892 (rank : 10)
Query Neighborhood Hits	281	Target Neighborhood Hits	524	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

MYLK_MOUSE
θ value	2.61198e-07 (rank : 20)	NC score	0.281247 (rank : 181)
Query Neighborhood Hits	281	Target Neighborhood Hits	1489	Shared Neighborhood Hits	202
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

ROBO3_HUMAN
θ value	2.61198e-07 (rank : 21)	NC score	0.606517 (rank : 13)
Query Neighborhood Hits	281	Target Neighborhood Hits	570	Shared Neighborhood Hits	202
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

PUNC_HUMAN
θ value	3.41135e-07 (rank : 22)	NC score	0.613503 (rank : 6)
Query Neighborhood Hits	281	Target Neighborhood Hits	449	Shared Neighborhood Hits	199
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

AGRIN_HUMAN
θ value	4.45536e-07 (rank : 23)	NC score	0.166105 (rank : 305)
Query Neighborhood Hits	281	Target Neighborhood Hits	582	Shared Neighborhood Hits	62
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ROBO2_MOUSE
θ value	4.45536e-07 (rank : 24)	NC score	0.610298 (rank : 11)
Query Neighborhood Hits	281	Target Neighborhood Hits	504	Shared Neighborhood Hits	200
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

PUNC_MOUSE
θ value	7.59969e-07 (rank : 25)	NC score	0.611487 (rank : 9)
Query Neighborhood Hits	281	Target Neighborhood Hits	501	Shared Neighborhood Hits	202
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

PTPRS_HUMAN
θ value	9.92553e-07 (rank : 26)	NC score	0.423234 (rank : 119)
Query Neighborhood Hits	281	Target Neighborhood Hits	472	Shared Neighborhood Hits	193
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

L1CAM_MOUSE
θ value	1.29631e-06 (rank : 27)	NC score	0.563692 (rank : 36)
Query Neighborhood Hits	281	Target Neighborhood Hits	457	Shared Neighborhood Hits	202
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CRIM1_HUMAN
θ value	2.88788e-06 (rank : 28)	NC score	0.170314 (rank : 298)
Query Neighborhood Hits	281	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

MYLK_HUMAN
θ value	2.88788e-06 (rank : 29)	NC score	0.280248 (rank : 182)
Query Neighborhood Hits	281	Target Neighborhood Hits	1328	Shared Neighborhood Hits	206
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

TRIO_HUMAN
θ value	4.92598e-06 (rank : 30)	NC score	0.159061 (rank : 319)
Query Neighborhood Hits	281	Target Neighborhood Hits	1580	Shared Neighborhood Hits	188
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

SDK1_HUMAN
θ value	8.40245e-06 (rank : 31)	NC score	0.561419 (rank : 38)
Query Neighborhood Hits	281	Target Neighborhood Hits	511	Shared Neighborhood Hits	201
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

TITIN_HUMAN
θ value	1.09739e-05 (rank : 32)	NC score	0.351633 (rank : 152)
Query Neighborhood Hits	281	Target Neighborhood Hits	2923	Shared Neighborhood Hits	209
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

NFASC_MOUSE
θ value	1.43324e-05 (rank : 33)	NC score	0.574725 (rank : 26)
Query Neighborhood Hits	281	Target Neighborhood Hits	475	Shared Neighborhood Hits	201
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

PGBM_HUMAN
θ value	1.43324e-05 (rank : 34)	NC score	0.440863 (rank : 106)
Query Neighborhood Hits	281	Target Neighborhood Hits	1113	Shared Neighborhood Hits	225
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NFASC_HUMAN
θ value	1.87187e-05 (rank : 35)	NC score	0.570531 (rank : 31)
Query Neighborhood Hits	281	Target Neighborhood Hits	497	Shared Neighborhood Hits	201
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

PTPRF_HUMAN
θ value	1.87187e-05 (rank : 36)	NC score	0.422641 (rank : 120)
Query Neighborhood Hits	281	Target Neighborhood Hits	489	Shared Neighborhood Hits	197
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

DSCAM_HUMAN
θ value	2.44474e-05 (rank : 37)	NC score	0.578942 (rank : 25)
Query Neighborhood Hits	281	Target Neighborhood Hits	524	Shared Neighborhood Hits	206
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

HMCN1_HUMAN
θ value	2.44474e-05 (rank : 38)	NC score	0.429264 (rank : 111)
Query Neighborhood Hits	281	Target Neighborhood Hits	983	Shared Neighborhood Hits	224
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

PTPRD_MOUSE
θ value	4.1701e-05 (rank : 39)	NC score	0.424378 (rank : 118)
Query Neighborhood Hits	281	Target Neighborhood Hits	491	Shared Neighborhood Hits	194
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

L1CAM_HUMAN
θ value	5.44631e-05 (rank : 40)	NC score	0.560502 (rank : 39)
Query Neighborhood Hits	281	Target Neighborhood Hits	457	Shared Neighborhood Hits	200
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

NCA11_HUMAN
θ value	5.44631e-05 (rank : 41)	NC score	0.570873 (rank : 30)
Query Neighborhood Hits	281	Target Neighborhood Hits	443	Shared Neighborhood Hits	203
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

NCA11_MOUSE
θ value	5.44631e-05 (rank : 42)	NC score	0.554046 (rank : 45)
Query Neighborhood Hits	281	Target Neighborhood Hits	661	Shared Neighborhood Hits	203
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCA12_HUMAN
θ value	5.44631e-05 (rank : 43)	NC score	0.572864 (rank : 27)
Query Neighborhood Hits	281	Target Neighborhood Hits	437	Shared Neighborhood Hits	203
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

NCA12_MOUSE
θ value	5.44631e-05 (rank : 44)	NC score	0.569177 (rank : 32)
Query Neighborhood Hits	281	Target Neighborhood Hits	399	Shared Neighborhood Hits	203
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

PTPRD_HUMAN
θ value	7.1131e-05 (rank : 45)	NC score	0.416867 (rank : 121)
Query Neighborhood Hits	281	Target Neighborhood Hits	485	Shared Neighborhood Hits	190
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PGBM_MOUSE
θ value	0.000121331 (rank : 46)	NC score	0.429062 (rank : 112)
Query Neighborhood Hits	281	Target Neighborhood Hits	1073	Shared Neighborhood Hits	227
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

FGFR3_MOUSE
θ value	0.000158464 (rank : 47)	NC score	0.222993 (rank : 223)
Query Neighborhood Hits	281	Target Neighborhood Hits	1059	Shared Neighborhood Hits	193
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

SDK2_HUMAN
θ value	0.000158464 (rank : 48)	NC score	0.557193 (rank : 41)
Query Neighborhood Hits	281	Target Neighborhood Hits	495	Shared Neighborhood Hits	203
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
θ value	0.00020696 (rank : 49)	NC score	0.555299 (rank : 43)
Query Neighborhood Hits	281	Target Neighborhood Hits	480	Shared Neighborhood Hits	202
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

FGFR4_MOUSE
θ value	0.000270298 (rank : 50)	NC score	0.229602 (rank : 210)
Query Neighborhood Hits	281	Target Neighborhood Hits	1026	Shared Neighborhood Hits	196
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

SPEG_MOUSE
θ value	0.000270298 (rank : 51)	NC score	0.282842 (rank : 179)
Query Neighborhood Hits	281	Target Neighborhood Hits	1959	Shared Neighborhood Hits	201
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MYOTI_MOUSE
θ value	0.00035302 (rank : 52)	NC score	0.586085 (rank : 20)
Query Neighborhood Hits	281	Target Neighborhood Hits	297	Shared Neighborhood Hits	187
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MYPC2_HUMAN
θ value	0.00035302 (rank : 53)	NC score	0.526741 (rank : 65)
Query Neighborhood Hits	281	Target Neighborhood Hits	316	Shared Neighborhood Hits	184
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

SPEG_HUMAN
θ value	0.00035302 (rank : 54)	NC score	0.282914 (rank : 178)
Query Neighborhood Hits	281	Target Neighborhood Hits	1762	Shared Neighborhood Hits	202
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

IBP2_MOUSE
θ value	0.000461057 (rank : 55)	NC score	0.241781 (rank : 199)
Query Neighborhood Hits	281	Target Neighborhood Hits	65	Shared Neighborhood Hits	41
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

NRCAM_MOUSE
θ value	0.000461057 (rank : 56)	NC score	0.550991 (rank : 48)
Query Neighborhood Hits	281	Target Neighborhood Hits	432	Shared Neighborhood Hits	198
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

FGFR3_HUMAN
θ value	0.000602161 (rank : 57)	NC score	0.214620 (rank : 233)
Query Neighborhood Hits	281	Target Neighborhood Hits	1042	Shared Neighborhood Hits	191
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

LRIG1_MOUSE
θ value	0.000602161 (rank : 58)	NC score	0.426272 (rank : 116)
Query Neighborhood Hits	281	Target Neighborhood Hits	627	Shared Neighborhood Hits	202
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

MYPC2_MOUSE
θ value	0.000602161 (rank : 59)	NC score	0.522972 (rank : 67)
Query Neighborhood Hits	281	Target Neighborhood Hits	297	Shared Neighborhood Hits	183
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

CHL1_HUMAN
θ value	0.000786445 (rank : 60)	NC score	0.561932 (rank : 37)
Query Neighborhood Hits	281	Target Neighborhood Hits	413	Shared Neighborhood Hits	199
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

IBP3_HUMAN
θ value	0.000786445 (rank : 61)	NC score	0.251166 (rank : 194)
Query Neighborhood Hits	281	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

MYPC3_MOUSE
θ value	0.000786445 (rank : 62)	NC score	0.500821 (rank : 73)
Query Neighborhood Hits	281	Target Neighborhood Hits	310	Shared Neighborhood Hits	175
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

ROBO4_MOUSE
θ value	0.000786445 (rank : 63)	NC score	0.566584 (rank : 33)
Query Neighborhood Hits	281	Target Neighborhood Hits	358	Shared Neighborhood Hits	181
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

ROR2_MOUSE
θ value	0.000786445 (rank : 64)	NC score	0.182141 (rank : 281)
Query Neighborhood Hits	281	Target Neighborhood Hits	1000	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

SDK1_MOUSE
θ value	0.000786445 (rank : 65)	NC score	0.554824 (rank : 44)
Query Neighborhood Hits	281	Target Neighborhood Hits	495	Shared Neighborhood Hits	199
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

CHL1_MOUSE
θ value	0.00134147 (rank : 66)	NC score	0.559288 (rank : 40)
Query Neighborhood Hits	281	Target Neighborhood Hits	402	Shared Neighborhood Hits	201
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

FGFR1_HUMAN
θ value	0.00134147 (rank : 67)	NC score	0.223931 (rank : 220)
Query Neighborhood Hits	281	Target Neighborhood Hits	1069	Shared Neighborhood Hits	192
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR1_MOUSE
θ value	0.00134147 (rank : 68)	NC score	0.223921 (rank : 221)
Query Neighborhood Hits	281	Target Neighborhood Hits	1068	Shared Neighborhood Hits	191
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

ISK6_HUMAN
θ value	0.00134147 (rank : 69)	NC score	0.216593 (rank : 230)
Query Neighborhood Hits	281	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

MYOTI_HUMAN
θ value	0.00134147 (rank : 70)	NC score	0.587022 (rank : 19)
Query Neighborhood Hits	281	Target Neighborhood Hits	292	Shared Neighborhood Hits	196
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

NRCAM_HUMAN
θ value	0.00134147 (rank : 71)	NC score	0.543949 (rank : 51)
Query Neighborhood Hits	281	Target Neighborhood Hits	439	Shared Neighborhood Hits	199
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

OPCM_HUMAN
θ value	0.00134147 (rank : 72)	NC score	0.519992 (rank : 69)
Query Neighborhood Hits	281	Target Neighborhood Hits	332	Shared Neighborhood Hits	199
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

RAGE_HUMAN
θ value	0.00134147 (rank : 73)	NC score	0.501999 (rank : 72)
Query Neighborhood Hits	281	Target Neighborhood Hits	269	Shared Neighborhood Hits	183
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

ATL3_HUMAN
θ value	0.00175202 (rank : 74)	NC score	0.344948 (rank : 154)
Query Neighborhood Hits	281	Target Neighborhood Hits	414	Shared Neighborhood Hits	204
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

CNTN5_MOUSE
θ value	0.00228821 (rank : 75)	NC score	0.541348 (rank : 55)
Query Neighborhood Hits	281	Target Neighborhood Hits	434	Shared Neighborhood Hits	203
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

DUET_HUMAN
θ value	0.00228821 (rank : 76)	NC score	0.204797 (rank : 245)
Query Neighborhood Hits	281	Target Neighborhood Hits	1220	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

FGFR4_HUMAN
θ value	0.00228821 (rank : 77)	NC score	0.224822 (rank : 218)
Query Neighborhood Hits	281	Target Neighborhood Hits	1037	Shared Neighborhood Hits	197
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

FST_MOUSE
θ value	0.00228821 (rank : 78)	NC score	0.209974 (rank : 236)
Query Neighborhood Hits	281	Target Neighborhood Hits	146	Shared Neighborhood Hits	43
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

LRIG1_HUMAN
θ value	0.00228821 (rank : 79)	NC score	0.431251 (rank : 108)
Query Neighborhood Hits	281	Target Neighborhood Hits	654	Shared Neighborhood Hits	203
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

MYBPH_MOUSE
θ value	0.00228821 (rank : 80)	NC score	0.490196 (rank : 80)
Query Neighborhood Hits	281	Target Neighborhood Hits	290	Shared Neighborhood Hits	177
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

ROR2_HUMAN
θ value	0.00228821 (rank : 81)	NC score	0.174637 (rank : 293)
Query Neighborhood Hits	281	Target Neighborhood Hits	1014	Shared Neighborhood Hits	179
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

BOC_MOUSE
θ value	0.00298849 (rank : 82)	NC score	0.572542 (rank : 29)
Query Neighborhood Hits	281	Target Neighborhood Hits	433	Shared Neighborhood Hits	202
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CNTN5_HUMAN
θ value	0.00298849 (rank : 83)	NC score	0.543295 (rank : 52)
Query Neighborhood Hits	281	Target Neighborhood Hits	446	Shared Neighborhood Hits	202
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

HTRA4_HUMAN
θ value	0.00298849 (rank : 84)	NC score	0.336980 (rank : 156)
Query Neighborhood Hits	281	Target Neighborhood Hits	119	Shared Neighborhood Hits	39
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

IBP2_HUMAN
θ value	0.00298849 (rank : 85)	NC score	0.237097 (rank : 201)
Query Neighborhood Hits	281	Target Neighborhood Hits	61	Shared Neighborhood Hits	40
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

LRFN4_MOUSE
θ value	0.00298849 (rank : 86)	NC score	0.325152 (rank : 158)
Query Neighborhood Hits	281	Target Neighborhood Hits	442	Shared Neighborhood Hits	174
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRIG3_MOUSE
θ value	0.00298849 (rank : 87)	NC score	0.412634 (rank : 127)
Query Neighborhood Hits	281	Target Neighborhood Hits	611	Shared Neighborhood Hits	201
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

MUSK_HUMAN
θ value	0.00298849 (rank : 88)	NC score	0.283618 (rank : 177)
Query Neighborhood Hits	281	Target Neighborhood Hits	1074	Shared Neighborhood Hits	200
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MYPN_MOUSE
θ value	0.00298849 (rank : 89)	NC score	0.591303 (rank : 17)
Query Neighborhood Hits	281	Target Neighborhood Hits	421	Shared Neighborhood Hits	197
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

CNTN3_HUMAN
θ value	0.00390308 (rank : 90)	NC score	0.538884 (rank : 56)
Query Neighborhood Hits	281	Target Neighborhood Hits	455	Shared Neighborhood Hits	204
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN6_HUMAN
θ value	0.00390308 (rank : 91)	NC score	0.538827 (rank : 57)
Query Neighborhood Hits	281	Target Neighborhood Hits	422	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

FGFR2_HUMAN
θ value	0.00390308 (rank : 92)	NC score	0.211394 (rank : 234)
Query Neighborhood Hits	281	Target Neighborhood Hits	1062	Shared Neighborhood Hits	191
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

IBP5_MOUSE
θ value	0.00390308 (rank : 93)	NC score	0.236225 (rank : 203)
Query Neighborhood Hits	281	Target Neighborhood Hits	68	Shared Neighborhood Hits	40
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

MYPN_HUMAN
θ value	0.00390308 (rank : 94)	NC score	0.595544 (rank : 14)
Query Neighborhood Hits	281	Target Neighborhood Hits	418	Shared Neighborhood Hits	198
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

NPHN_HUMAN
θ value	0.00390308 (rank : 95)	NC score	0.500572 (rank : 74)
Query Neighborhood Hits	281	Target Neighborhood Hits	362	Shared Neighborhood Hits	189
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

SN_HUMAN
θ value	0.00390308 (rank : 96)	NC score	0.463256 (rank : 96)
Query Neighborhood Hits	281	Target Neighborhood Hits	434	Shared Neighborhood Hits	196
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

FGFR2_MOUSE
θ value	0.00509761 (rank : 97)	NC score	0.203633 (rank : 247)
Query Neighborhood Hits	281	Target Neighborhood Hits	1062	Shared Neighborhood Hits	186
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

FSTL4_HUMAN
θ value	0.00509761 (rank : 98)	NC score	0.537548 (rank : 60)
Query Neighborhood Hits	281	Target Neighborhood Hits	344	Shared Neighborhood Hits	223
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

IBP5_HUMAN
θ value	0.00509761 (rank : 99)	NC score	0.235335 (rank : 205)
Query Neighborhood Hits	281	Target Neighborhood Hits	68	Shared Neighborhood Hits	40
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

MUSK_MOUSE
θ value	0.00509761 (rank : 100)	NC score	0.286123 (rank : 175)
Query Neighborhood Hits	281	Target Neighborhood Hits	1057	Shared Neighborhood Hits	200
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MYPC3_HUMAN
θ value	0.00509761 (rank : 101)	NC score	0.496083 (rank : 75)
Query Neighborhood Hits	281	Target Neighborhood Hits	318	Shared Neighborhood Hits	177
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

VSIG2_HUMAN
θ value	0.00509761 (rank : 102)	NC score	0.424405 (rank : 117)
Query Neighborhood Hits	281	Target Neighborhood Hits	321	Shared Neighborhood Hits	180
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

CILP2_HUMAN
θ value	0.00665767 (rank : 103)	NC score	0.300115 (rank : 172)
Query Neighborhood Hits	281	Target Neighborhood Hits	307	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CNTN2_MOUSE
θ value	0.00665767 (rank : 104)	NC score	0.541682 (rank : 54)
Query Neighborhood Hits	281	Target Neighborhood Hits	450	Shared Neighborhood Hits	205
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

FSTL1_HUMAN
θ value	0.00665767 (rank : 105)	NC score	0.203604 (rank : 248)
Query Neighborhood Hits	281	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FST_HUMAN
θ value	0.00665767 (rank : 106)	NC score	0.207137 (rank : 242)
Query Neighborhood Hits	281	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

KIRR3_MOUSE
θ value	0.00665767 (rank : 107)	NC score	0.448255 (rank : 103)
Query Neighborhood Hits	281	Target Neighborhood Hits	292	Shared Neighborhood Hits	170
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

LRFN4_HUMAN
θ value	0.00665767 (rank : 108)	NC score	0.326845 (rank : 157)
Query Neighborhood Hits	281	Target Neighborhood Hits	462	Shared Neighborhood Hits	175
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

MYPC1_HUMAN
θ value	0.00665767 (rank : 109)	NC score	0.520541 (rank : 68)
Query Neighborhood Hits	281	Target Neighborhood Hits	303	Shared Neighborhood Hits	185
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

SMOC1_MOUSE
θ value	0.00665767 (rank : 110)	NC score	0.174985 (rank : 292)
Query Neighborhood Hits	281	Target Neighborhood Hits	74	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

SN_MOUSE
θ value	0.00665767 (rank : 111)	NC score	0.464210 (rank : 94)
Query Neighborhood Hits	281	Target Neighborhood Hits	416	Shared Neighborhood Hits	197
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

CNTN2_HUMAN
θ value	0.00869519 (rank : 112)	NC score	0.541890 (rank : 53)
Query Neighborhood Hits	281	Target Neighborhood Hits	440	Shared Neighborhood Hits	203
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

ROBO4_HUMAN
θ value	0.00869519 (rank : 113)	NC score	0.564773 (rank : 35)
Query Neighborhood Hits	281	Target Neighborhood Hits	364	Shared Neighborhood Hits	182
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

BOC_HUMAN
θ value	0.0113563 (rank : 114)	NC score	0.572672 (rank : 28)
Query Neighborhood Hits	281	Target Neighborhood Hits	543	Shared Neighborhood Hits	204
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CTGF_HUMAN
θ value	0.0113563 (rank : 115)	NC score	0.170022 (rank : 299)
Query Neighborhood Hits	281	Target Neighborhood Hits	128	Shared Neighborhood Hits	37
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

FSTL1_MOUSE
θ value	0.0113563 (rank : 116)	NC score	0.200787 (rank : 254)
Query Neighborhood Hits	281	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

KIRR2_MOUSE
θ value	0.0113563 (rank : 117)	NC score	0.472704 (rank : 91)
Query Neighborhood Hits	281	Target Neighborhood Hits	326	Shared Neighborhood Hits	177
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

LRC24_HUMAN
θ value	0.0113563 (rank : 118)	NC score	0.249186 (rank : 195)
Query Neighborhood Hits	281	Target Neighborhood Hits	404	Shared Neighborhood Hits	162
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

MFA3L_HUMAN
θ value	0.0113563 (rank : 119)	NC score	0.430842 (rank : 110)
Query Neighborhood Hits	281	Target Neighborhood Hits	230	Shared Neighborhood Hits	174
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

LRIG2_HUMAN
θ value	0.0148317 (rank : 120)	NC score	0.426941 (rank : 114)
Query Neighborhood Hits	281	Target Neighborhood Hits	595	Shared Neighborhood Hits	202
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

MAG_MOUSE
θ value	0.0148317 (rank : 121)	NC score	0.493230 (rank : 77)
Query Neighborhood Hits	281	Target Neighborhood Hits	271	Shared Neighborhood Hits	188
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

TICN2_MOUSE
θ value	0.0148317 (rank : 122)	NC score	0.158111 (rank : 321)
Query Neighborhood Hits	281	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

KIRR3_HUMAN
θ value	0.0193708 (rank : 123)	NC score	0.447509 (rank : 104)
Query Neighborhood Hits	281	Target Neighborhood Hits	302	Shared Neighborhood Hits	172
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

LRRC4_HUMAN
θ value	0.0193708 (rank : 124)	NC score	0.196816 (rank : 262)
Query Neighborhood Hits	281	Target Neighborhood Hits	444	Shared Neighborhood Hits	153
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

MYOM1_MOUSE
θ value	0.0193708 (rank : 125)	NC score	0.493033 (rank : 78)
Query Neighborhood Hits	281	Target Neighborhood Hits	415	Shared Neighborhood Hits	178
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

SMOC1_HUMAN
θ value	0.0193708 (rank : 126)	NC score	0.164123 (rank : 307)
Query Neighborhood Hits	281	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC2_MOUSE
θ value	0.0193708 (rank : 127)	NC score	0.162070 (rank : 312)
Query Neighborhood Hits	281	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

VGFR1_MOUSE
θ value	0.0193708 (rank : 128)	NC score	0.253269 (rank : 193)
Query Neighborhood Hits	281	Target Neighborhood Hits	1118	Shared Neighborhood Hits	202
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

CNTN3_MOUSE
θ value	0.0252991 (rank : 129)	NC score	0.531136 (rank : 63)
Query Neighborhood Hits	281	Target Neighborhood Hits	447	Shared Neighborhood Hits	201
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

FSTL3_HUMAN
θ value	0.0252991 (rank : 130)	NC score	0.221856 (rank : 225)
Query Neighborhood Hits	281	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL4_MOUSE
θ value	0.0252991 (rank : 131)	NC score	0.538716 (rank : 58)
Query Neighborhood Hits	281	Target Neighborhood Hits	333	Shared Neighborhood Hits	224
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

MFA3L_MOUSE
θ value	0.0252991 (rank : 132)	NC score	0.379249 (rank : 144)
Query Neighborhood Hits	281	Target Neighborhood Hits	214	Shared Neighborhood Hits	160
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

PTK7_HUMAN
θ value	0.0252991 (rank : 133)	NC score	0.310121 (rank : 165)
Query Neighborhood Hits	281	Target Neighborhood Hits	1103	Shared Neighborhood Hits	202
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

SIG12_MOUSE
θ value	0.0252991 (rank : 134)	NC score	0.178689 (rank : 286)
Query Neighborhood Hits	281	Target Neighborhood Hits	225	Shared Neighborhood Hits	117
SwissProt Accessions	Q91Y57	Gene names	Siglec12, Siglec5, Siglece, Siglecl1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (mSiglec-E) (Myeloid inhibitory siglec) (MIS).

CDON_MOUSE
θ value	0.0330416 (rank : 135)	NC score	0.565970 (rank : 34)
Query Neighborhood Hits	281	Target Neighborhood Hits	410	Shared Neighborhood Hits	200
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

LRFN3_MOUSE
θ value	0.0330416 (rank : 136)	NC score	0.305695 (rank : 167)
Query Neighborhood Hits	281	Target Neighborhood Hits	455	Shared Neighborhood Hits	179
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRIG3_HUMAN
θ value	0.0330416 (rank : 137)	NC score	0.406567 (rank : 135)
Query Neighborhood Hits	281	Target Neighborhood Hits	601	Shared Neighborhood Hits	200
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

NRG1_HUMAN
θ value	0.0330416 (rank : 138)	NC score	0.321658 (rank : 161)
Query Neighborhood Hits	281	Target Neighborhood Hits	285	Shared Neighborhood Hits	138
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

IBP4_HUMAN
θ value	0.0431538 (rank : 139)	NC score	0.195913 (rank : 264)
Query Neighborhood Hits	281	Target Neighborhood Hits	52	Shared Neighborhood Hits	35
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

LRIG2_MOUSE
θ value	0.0431538 (rank : 140)	NC score	0.426742 (rank : 115)
Query Neighborhood Hits	281	Target Neighborhood Hits	586	Shared Neighborhood Hits	203
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

NOV_HUMAN
θ value	0.0431538 (rank : 141)	NC score	0.146224 (rank : 344)
Query Neighborhood Hits	281	Target Neighborhood Hits	128	Shared Neighborhood Hits	37
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

MYBPH_HUMAN
θ value	0.0563607 (rank : 142)	NC score	0.477186 (rank : 89)
Query Neighborhood Hits	281	Target Neighborhood Hits	256	Shared Neighborhood Hits	176
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

NCAM2_HUMAN
θ value	0.0563607 (rank : 143)	NC score	0.555623 (rank : 42)
Query Neighborhood Hits	281	Target Neighborhood Hits	441	Shared Neighborhood Hits	203
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

TICN2_HUMAN
θ value	0.0563607 (rank : 144)	NC score	0.152048 (rank : 333)
Query Neighborhood Hits	281	Target Neighborhood Hits	68	Shared Neighborhood Hits	41
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

ISK6_MOUSE
θ value	0.0736092 (rank : 145)	NC score	0.187807 (rank : 276)
Query Neighborhood Hits	281	Target Neighborhood Hits	37	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

LRFN2_MOUSE
θ value	0.0736092 (rank : 146)	NC score	0.301043 (rank : 171)
Query Neighborhood Hits	281	Target Neighborhood Hits	450	Shared Neighborhood Hits	172
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

NCAM2_MOUSE
θ value	0.0736092 (rank : 147)	NC score	0.552704 (rank : 46)
Query Neighborhood Hits	281	Target Neighborhood Hits	472	Shared Neighborhood Hits	203
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

RECK_MOUSE
θ value	0.0736092 (rank : 148)	NC score	0.125989 (rank : 374)
Query Neighborhood Hits	281	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

CNTN4_HUMAN
θ value	0.0961366 (rank : 149)	NC score	0.545667 (rank : 49)
Query Neighborhood Hits	281	Target Neighborhood Hits	449	Shared Neighborhood Hits	202
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN6_MOUSE
θ value	0.0961366 (rank : 150)	NC score	0.536518 (rank : 61)
Query Neighborhood Hits	281	Target Neighborhood Hits	429	Shared Neighborhood Hits	200
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

FSTL5_MOUSE
θ value	0.0961366 (rank : 151)	NC score	0.525174 (rank : 66)
Query Neighborhood Hits	281	Target Neighborhood Hits	355	Shared Neighborhood Hits	217
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

KIRR2_HUMAN
θ value	0.0961366 (rank : 152)	NC score	0.479934 (rank : 86)
Query Neighborhood Hits	281	Target Neighborhood Hits	321	Shared Neighborhood Hits	177
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

LRC24_MOUSE
θ value	0.0961366 (rank : 153)	NC score	0.226912 (rank : 214)
Query Neighborhood Hits	281	Target Neighborhood Hits	387	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRFN2_HUMAN
θ value	0.0961366 (rank : 154)	NC score	0.311948 (rank : 164)
Query Neighborhood Hits	281	Target Neighborhood Hits	450	Shared Neighborhood Hits	172
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

MAG_HUMAN
θ value	0.0961366 (rank : 155)	NC score	0.488843 (rank : 82)
Query Neighborhood Hits	281	Target Neighborhood Hits	278	Shared Neighborhood Hits	189
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MDGA1_HUMAN
θ value	0.0961366 (rank : 156)	NC score	0.487524 (rank : 84)
Query Neighborhood Hits	281	Target Neighborhood Hits	358	Shared Neighborhood Hits	198
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

SMOC2_HUMAN
θ value	0.0961366 (rank : 157)	NC score	0.156176 (rank : 325)
Query Neighborhood Hits	281	Target Neighborhood Hits	88	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

CD276_HUMAN
θ value	0.125558 (rank : 158)	NC score	0.255381 (rank : 191)
Query Neighborhood Hits	281	Target Neighborhood Hits	261	Shared Neighborhood Hits	117
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CTGF_MOUSE
θ value	0.125558 (rank : 159)	NC score	0.135297 (rank : 359)
Query Neighborhood Hits	281	Target Neighborhood Hits	124	Shared Neighborhood Hits	37
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

IBP1_MOUSE
θ value	0.125558 (rank : 160)	NC score	0.224861 (rank : 217)
Query Neighborhood Hits	281	Target Neighborhood Hits	97	Shared Neighborhood Hits	40
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP4_MOUSE
θ value	0.125558 (rank : 161)	NC score	0.190027 (rank : 273)
Query Neighborhood Hits	281	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

WISP2_MOUSE
θ value	0.125558 (rank : 162)	NC score	0.143570 (rank : 348)
Query Neighborhood Hits	281	Target Neighborhood Hits	129	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

CNTN4_MOUSE
θ value	0.163984 (rank : 163)	NC score	0.544526 (rank : 50)
Query Neighborhood Hits	281	Target Neighborhood Hits	445	Shared Neighborhood Hits	202
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

FSTL5_HUMAN
θ value	0.163984 (rank : 164)	NC score	0.529857 (rank : 64)
Query Neighborhood Hits	281	Target Neighborhood Hits	347	Shared Neighborhood Hits	220
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

IBP3_MOUSE
θ value	0.163984 (rank : 165)	NC score	0.201607 (rank : 251)
Query Neighborhood Hits	281	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

LRFN3_HUMAN
θ value	0.163984 (rank : 166)	NC score	0.291758 (rank : 174)
Query Neighborhood Hits	281	Target Neighborhood Hits	444	Shared Neighborhood Hits	171
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

NTRI_MOUSE
θ value	0.163984 (rank : 167)	NC score	0.495255 (rank : 76)
Query Neighborhood Hits	281	Target Neighborhood Hits	342	Shared Neighborhood Hits	201
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

VGFR1_HUMAN
θ value	0.163984 (rank : 168)	NC score	0.256161 (rank : 190)
Query Neighborhood Hits	281	Target Neighborhood Hits	1109	Shared Neighborhood Hits	201
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

ESM1_HUMAN
θ value	0.21417 (rank : 169)	NC score	0.199747 (rank : 259)
Query Neighborhood Hits	281	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FGRL1_HUMAN
θ value	0.21417 (rank : 170)	NC score	0.585672 (rank : 21)
Query Neighborhood Hits	281	Target Neighborhood Hits	335	Shared Neighborhood Hits	198
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

LRRC4_MOUSE
θ value	0.21417 (rank : 171)	NC score	0.171008 (rank : 297)
Query Neighborhood Hits	281	Target Neighborhood Hits	412	Shared Neighborhood Hits	133
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

NGL1_HUMAN
θ value	0.21417 (rank : 172)	NC score	0.208972 (rank : 239)
Query Neighborhood Hits	281	Target Neighborhood Hits	511	Shared Neighborhood Hits	163
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_MOUSE
θ value	0.21417 (rank : 173)	NC score	0.209235 (rank : 238)
Query Neighborhood Hits	281	Target Neighborhood Hits	512	Shared Neighborhood Hits	163
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NRG2_MOUSE
θ value	0.21417 (rank : 174)	NC score	0.387039 (rank : 142)
Query Neighborhood Hits	281	Target Neighborhood Hits	392	Shared Neighborhood Hits	186
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

RECK_HUMAN
θ value	0.21417 (rank : 175)	NC score	0.125341 (rank : 377)
Query Neighborhood Hits	281	Target Neighborhood Hits	189	Shared Neighborhood Hits	38
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

SIG11_HUMAN
θ value	0.21417 (rank : 176)	NC score	0.398033 (rank : 139)
Query Neighborhood Hits	281	Target Neighborhood Hits	273	Shared Neighborhood Hits	180
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

CYR61_HUMAN
θ value	0.279714 (rank : 177)	NC score	0.147695 (rank : 343)
Query Neighborhood Hits	281	Target Neighborhood Hits	159	Shared Neighborhood Hits	37
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	0.279714 (rank : 178)	NC score	0.147867 (rank : 342)
Query Neighborhood Hits	281	Target Neighborhood Hits	156	Shared Neighborhood Hits	38
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

LAMA5_MOUSE
θ value	0.279714 (rank : 179)	NC score	0.042209 (rank : 632)
Query Neighborhood Hits	281	Target Neighborhood Hits	828	Shared Neighborhood Hits	34
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MYOM1_HUMAN
θ value	0.279714 (rank : 180)	NC score	0.471957 (rank : 92)
Query Neighborhood Hits	281	Target Neighborhood Hits	405	Shared Neighborhood Hits	177
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

NTRI_HUMAN
θ value	0.279714 (rank : 181)	NC score	0.491009 (rank : 79)
Query Neighborhood Hits	281	Target Neighborhood Hits	344	Shared Neighborhood Hits	200
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

RAGE_MOUSE
θ value	0.279714 (rank : 182)	NC score	0.459790 (rank : 97)
Query Neighborhood Hits	281	Target Neighborhood Hits	295	Shared Neighborhood Hits	169
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

WISP3_HUMAN
θ value	0.279714 (rank : 183)	NC score	0.138378 (rank : 356)
Query Neighborhood Hits	281	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

TEFF2_HUMAN
θ value	0.365318 (rank : 184)	NC score	0.160689 (rank : 316)
Query Neighborhood Hits	281	Target Neighborhood Hits	211	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	0.365318 (rank : 185)	NC score	0.162419 (rank : 310)
Query Neighborhood Hits	281	Target Neighborhood Hits	214	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

VSIG2_MOUSE
θ value	0.365318 (rank : 186)	NC score	0.409003 (rank : 132)
Query Neighborhood Hits	281	Target Neighborhood Hits	316	Shared Neighborhood Hits	178
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

CD276_MOUSE
θ value	0.47712 (rank : 187)	NC score	0.200153 (rank : 257)
Query Neighborhood Hits	281	Target Neighborhood Hits	243	Shared Neighborhood Hits	120
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CSF1R_MOUSE
θ value	0.47712 (rank : 188)	NC score	0.172435 (rank : 296)
Query Neighborhood Hits	281	Target Neighborhood Hits	983	Shared Neighborhood Hits	160
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

LSAMP_MOUSE
θ value	0.47712 (rank : 189)	NC score	0.506023 (rank : 71)
Query Neighborhood Hits	281	Target Neighborhood Hits	344	Shared Neighborhood Hits	198
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

NPTN_MOUSE
θ value	0.47712 (rank : 190)	NC score	0.474349 (rank : 90)
Query Neighborhood Hits	281	Target Neighborhood Hits	216	Shared Neighborhood Hits	166
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NRG2_HUMAN
θ value	0.47712 (rank : 191)	NC score	0.389173 (rank : 140)
Query Neighborhood Hits	281	Target Neighborhood Hits	419	Shared Neighborhood Hits	180
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

FGRL1_MOUSE
θ value	0.62314 (rank : 192)	NC score	0.582815 (rank : 24)
Query Neighborhood Hits	281	Target Neighborhood Hits	325	Shared Neighborhood Hits	199
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

FSTL3_MOUSE
θ value	0.62314 (rank : 193)	NC score	0.201579 (rank : 252)
Query Neighborhood Hits	281	Target Neighborhood Hits	152	Shared Neighborhood Hits	44
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

LRRN1_HUMAN
θ value	0.62314 (rank : 194)	NC score	0.247252 (rank : 196)
Query Neighborhood Hits	281	Target Neighborhood Hits	518	Shared Neighborhood Hits	188
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LSAMP_HUMAN
θ value	0.62314 (rank : 195)	NC score	0.506301 (rank : 70)
Query Neighborhood Hits	281	Target Neighborhood Hits	347	Shared Neighborhood Hits	198
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

SIGL8_HUMAN
θ value	0.62314 (rank : 196)	NC score	0.257549 (rank : 189)
Query Neighborhood Hits	281	Target Neighborhood Hits	252	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

ADAM8_HUMAN
θ value	0.813845 (rank : 197)	NC score	0.011059 (rank : 645)
Query Neighborhood Hits	281	Target Neighborhood Hits	327	Shared Neighborhood Hits	20
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

CNTN1_MOUSE
θ value	0.813845 (rank : 198)	NC score	0.538276 (rank : 59)
Query Neighborhood Hits	281	Target Neighborhood Hits	422	Shared Neighborhood Hits	199
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

TICN1_MOUSE
θ value	0.813845 (rank : 199)	NC score	0.127016 (rank : 370)
Query Neighborhood Hits	281	Target Neighborhood Hits	79	Shared Neighborhood Hits	43
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

CNTN1_HUMAN
θ value	1.06291 (rank : 200)	NC score	0.536411 (rank : 62)
Query Neighborhood Hits	281	Target Neighborhood Hits	431	Shared Neighborhood Hits	199
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

ESM1_MOUSE
θ value	1.06291 (rank : 201)	NC score	0.224072 (rank : 219)
Query Neighborhood Hits	281	Target Neighborhood Hits	107	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

IGSF8_MOUSE
θ value	1.06291 (rank : 202)	NC score	0.094187 (rank : 428)
Query Neighborhood Hits	281	Target Neighborhood Hits	94	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R366, Q8R0L7	Gene names	Igsf8, Ewi2, Kct4, Pgrl
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (Prostaglandin regulatory- like protein) (CD316 antigen).

LRC21_MOUSE
θ value	1.06291 (rank : 203)	NC score	0.279504 (rank : 183)
Query Neighborhood Hits	281	Target Neighborhood Hits	462	Shared Neighborhood Hits	176
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

MT4_HUMAN
θ value	1.06291 (rank : 204)	NC score	0.091374 (rank : 442)
Query Neighborhood Hits	281	Target Neighborhood Hits	83	Shared Neighborhood Hits	11
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	1.06291 (rank : 205)	NC score	0.082239 (rank : 472)
Query Neighborhood Hits	281	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

BTNL2_HUMAN
θ value	1.38821 (rank : 206)	NC score	0.106150 (rank : 410)
Query Neighborhood Hits	281	Target Neighborhood Hits	164	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

CI094_HUMAN
θ value	1.38821 (rank : 207)	NC score	0.416488 (rank : 123)
Query Neighborhood Hits	281	Target Neighborhood Hits	310	Shared Neighborhood Hits	189
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

KIT_HUMAN
θ value	1.38821 (rank : 208)	NC score	0.134257 (rank : 363)
Query Neighborhood Hits	281	Target Neighborhood Hits	953	Shared Neighborhood Hits	138
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	1.38821 (rank : 209)	NC score	0.140957 (rank : 352)
Query Neighborhood Hits	281	Target Neighborhood Hits	949	Shared Neighborhood Hits	147
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

LRRN1_MOUSE
θ value	1.38821 (rank : 210)	NC score	0.236771 (rank : 202)
Query Neighborhood Hits	281	Target Neighborhood Hits	508	Shared Neighborhood Hits	185
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

MYOM2_HUMAN
θ value	1.38821 (rank : 211)	NC score	0.479824 (rank : 87)
Query Neighborhood Hits	281	Target Neighborhood Hits	341	Shared Neighborhood Hits	173
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

NPTN_HUMAN
θ value	1.38821 (rank : 212)	NC score	0.467232 (rank : 93)
Query Neighborhood Hits	281	Target Neighborhood Hits	212	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

SCN2B_HUMAN
θ value	1.38821 (rank : 213)	NC score	0.054079 (rank : 576)
Query Neighborhood Hits	281	Target Neighborhood Hits	88	Shared Neighborhood Hits	20
SwissProt Accessions	O60939, O75302, Q9UNN3	Gene names	SCN2B
Domain Architecture
Description	Sodium channel beta-2 subunit precursor.

SIG12_HUMAN
θ value	1.38821 (rank : 214)	NC score	0.244555 (rank : 198)
Query Neighborhood Hits	281	Target Neighborhood Hits	245	Shared Neighborhood Hits	166
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

TYRO3_MOUSE
θ value	1.38821 (rank : 215)	NC score	0.191864 (rank : 270)
Query Neighborhood Hits	281	Target Neighborhood Hits	1007	Shared Neighborhood Hits	176
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

IBP1_HUMAN
θ value	1.81305 (rank : 216)	NC score	0.200294 (rank : 256)
Query Neighborhood Hits	281	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IGSF8_HUMAN
θ value	1.81305 (rank : 217)	NC score	0.096568 (rank : 425)
Query Neighborhood Hits	281	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	Q969P0, Q8NG09, Q96DP4, Q9BTG9	Gene names	IGSF8, CD81P3, EWI2, KCT4
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (LIR-D1) (CD316 antigen).

JAM2_HUMAN
θ value	1.81305 (rank : 218)	NC score	0.411234 (rank : 129)
Query Neighborhood Hits	281	Target Neighborhood Hits	304	Shared Neighborhood Hits	189
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

LRRN5_HUMAN
θ value	1.81305 (rank : 219)	NC score	0.234055 (rank : 206)
Query Neighborhood Hits	281	Target Neighborhood Hits	493	Shared Neighborhood Hits	181
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

SIGIR_MOUSE
θ value	1.81305 (rank : 220)	NC score	0.089708 (rank : 444)
Query Neighborhood Hits	281	Target Neighborhood Hits	95	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JLZ8, Q52L48	Gene names	Sigirr, Tir8
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

BMPER_MOUSE
θ value	2.36792 (rank : 221)	NC score	0.044382 (rank : 630)
Query Neighborhood Hits	281	Target Neighborhood Hits	194	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CEAM5_HUMAN
θ value	2.36792 (rank : 222)	NC score	0.360470 (rank : 150)
Query Neighborhood Hits	281	Target Neighborhood Hits	343	Shared Neighborhood Hits	180
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

EI2BE_MOUSE
θ value	2.36792 (rank : 223)	NC score	0.023456 (rank : 638)
Query Neighborhood Hits	281	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHW4, Q3TU39	Gene names	Eif2b5
Domain Architecture	No domain graphic available
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

ESAM_HUMAN
θ value	2.36792 (rank : 224)	NC score	0.264490 (rank : 188)
Query Neighborhood Hits	281	Target Neighborhood Hits	251	Shared Neighborhood Hits	130
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

ESAM_MOUSE
θ value	2.36792 (rank : 225)	NC score	0.240021 (rank : 200)
Query Neighborhood Hits	281	Target Neighborhood Hits	222	Shared Neighborhood Hits	131
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

ICAM5_MOUSE
θ value	2.36792 (rank : 226)	NC score	0.427133 (rank : 113)
Query Neighborhood Hits	281	Target Neighborhood Hits	308	Shared Neighborhood Hits	183
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

TMIGD_MOUSE
θ value	2.36792 (rank : 227)	NC score	0.456198 (rank : 100)
Query Neighborhood Hits	281	Target Neighborhood Hits	234	Shared Neighborhood Hits	171
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

WISP2_HUMAN
θ value	2.36792 (rank : 228)	NC score	0.150812 (rank : 334)
Query Neighborhood Hits	281	Target Neighborhood Hits	126	Shared Neighborhood Hits	36
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

CDON_HUMAN
θ value	3.0926 (rank : 229)	NC score	0.551610 (rank : 47)
Query Neighborhood Hits	281	Target Neighborhood Hits	412	Shared Neighborhood Hits	200
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

LRC4B_HUMAN
θ value	3.0926 (rank : 230)	NC score	0.205384 (rank : 244)
Query Neighborhood Hits	281	Target Neighborhood Hits	479	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRC4B_MOUSE
θ value	3.0926 (rank : 231)	NC score	0.207218 (rank : 241)
Query Neighborhood Hits	281	Target Neighborhood Hits	484	Shared Neighborhood Hits	163
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRRN3_HUMAN
θ value	3.0926 (rank : 232)	NC score	0.245801 (rank : 197)
Query Neighborhood Hits	281	Target Neighborhood Hits	461	Shared Neighborhood Hits	170
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

MAMC1_HUMAN
θ value	3.0926 (rank : 233)	NC score	0.489113 (rank : 81)
Query Neighborhood Hits	281	Target Neighborhood Hits	357	Shared Neighborhood Hits	200
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	3.0926 (rank : 234)	NC score	0.487800 (rank : 83)
Query Neighborhood Hits	281	Target Neighborhood Hits	357	Shared Neighborhood Hits	200
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MUC18_MOUSE
θ value	3.0926 (rank : 235)	NC score	0.402321 (rank : 136)
Query Neighborhood Hits	281	Target Neighborhood Hits	292	Shared Neighborhood Hits	164
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

NEGR1_HUMAN
θ value	3.0926 (rank : 236)	NC score	0.482014 (rank : 85)
Query Neighborhood Hits	281	Target Neighborhood Hits	346	Shared Neighborhood Hits	197
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

TMIGD_HUMAN
θ value	3.0926 (rank : 237)	NC score	0.457043 (rank : 99)
Query Neighborhood Hits	281	Target Neighborhood Hits	240	Shared Neighborhood Hits	165
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TYRO3_HUMAN
θ value	3.0926 (rank : 238)	NC score	0.193886 (rank : 267)
Query Neighborhood Hits	281	Target Neighborhood Hits	995	Shared Neighborhood Hits	170
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

ZN425_HUMAN
θ value	3.0926 (rank : 239)	NC score	-0.009523 (rank : 648)
Query Neighborhood Hits	281	Target Neighborhood Hits	795	Shared Neighborhood Hits	5
SwissProt Accessions	Q6IV72	Gene names	ZNF425
Domain Architecture	No domain graphic available
Description	Zinc finger protein 425.

CD80_HUMAN
θ value	4.03905 (rank : 240)	NC score	0.139330 (rank : 354)
Query Neighborhood Hits	281	Target Neighborhood Hits	129	Shared Neighborhood Hits	71
SwissProt Accessions	P33681	Gene names	CD80, CD28LG, CD28LG1, LAB7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7.1) (B7) (BB1).

IPK2_HUMAN
θ value	4.03905 (rank : 241)	NC score	0.084585 (rank : 459)
Query Neighborhood Hits	281	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

KIRR1_MOUSE
θ value	4.03905 (rank : 242)	NC score	0.411984 (rank : 128)
Query Neighborhood Hits	281	Target Neighborhood Hits	403	Shared Neighborhood Hits	168
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

NEGR1_MOUSE
θ value	4.03905 (rank : 243)	NC score	0.478936 (rank : 88)
Query Neighborhood Hits	281	Target Neighborhood Hits	349	Shared Neighborhood Hits	197
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

PGCA_HUMAN
θ value	4.03905 (rank : 244)	NC score	0.012506 (rank : 644)
Query Neighborhood Hits	281	Target Neighborhood Hits	821	Shared Neighborhood Hits	39
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PSG11_HUMAN
θ value	4.03905 (rank : 245)	NC score	0.216791 (rank : 229)
Query Neighborhood Hits	281	Target Neighborhood Hits	223	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

SIGL5_HUMAN
θ value	4.03905 (rank : 246)	NC score	0.254358 (rank : 192)
Query Neighborhood Hits	281	Target Neighborhood Hits	246	Shared Neighborhood Hits	143
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

STAB1_HUMAN
θ value	4.03905 (rank : 247)	NC score	0.025089 (rank : 637)
Query Neighborhood Hits	281	Target Neighborhood Hits	546	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

BMPER_HUMAN
θ value	5.27518 (rank : 248)	NC score	0.042331 (rank : 631)
Query Neighborhood Hits	281	Target Neighborhood Hits	175	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CD22_HUMAN
θ value	5.27518 (rank : 249)	NC score	0.408544 (rank : 133)
Query Neighborhood Hits	281	Target Neighborhood Hits	365	Shared Neighborhood Hits	176
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

EGFL7_HUMAN
θ value	5.27518 (rank : 250)	NC score	0.019096 (rank : 641)
Query Neighborhood Hits	281	Target Neighborhood Hits	325	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

ISK3_MOUSE
θ value	5.27518 (rank : 251)	NC score	0.097614 (rank : 422)
Query Neighborhood Hits	281	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

MOG_MOUSE
θ value	5.27518 (rank : 252)	NC score	0.042102 (rank : 633)
Query Neighborhood Hits	281	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MUC18_HUMAN
θ value	5.27518 (rank : 253)	NC score	0.408368 (rank : 134)
Query Neighborhood Hits	281	Target Neighborhood Hits	275	Shared Neighborhood Hits	160
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

NOTC1_HUMAN
θ value	5.27518 (rank : 254)	NC score	0.020203 (rank : 640)
Query Neighborhood Hits	281	Target Neighborhood Hits	906	Shared Neighborhood Hits	33
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SEM3F_HUMAN
θ value	5.27518 (rank : 255)	NC score	0.016346 (rank : 642)
Query Neighborhood Hits	281	Target Neighborhood Hits	100	Shared Neighborhood Hits	29
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

SPRL1_HUMAN
θ value	5.27518 (rank : 256)	NC score	0.068238 (rank : 504)
Query Neighborhood Hits	281	Target Neighborhood Hits	231	Shared Neighborhood Hits	30
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

TICN1_HUMAN
θ value	5.27518 (rank : 257)	NC score	0.117011 (rank : 395)
Query Neighborhood Hits	281	Target Neighborhood Hits	70	Shared Neighborhood Hits	38
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

UFO_MOUSE
θ value	5.27518 (rank : 258)	NC score	0.152363 (rank : 332)
Query Neighborhood Hits	281	Target Neighborhood Hits	988	Shared Neighborhood Hits	152
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

UNC5C_MOUSE
θ value	5.27518 (rank : 259)	NC score	0.173781 (rank : 294)
Query Neighborhood Hits	281	Target Neighborhood Hits	225	Shared Neighborhood Hits	116
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

VGFR2_MOUSE
θ value	5.27518 (rank : 260)	NC score	0.232073 (rank : 208)
Query Neighborhood Hits	281	Target Neighborhood Hits	1089	Shared Neighborhood Hits	197
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

EI2BE_HUMAN
θ value	6.88961 (rank : 261)	NC score	0.020322 (rank : 639)
Query Neighborhood Hits	281	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q13144, Q96D04	Gene names	EIF2B5, EIF2BE
Domain Architecture
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

ICAM5_HUMAN
θ value	6.88961 (rank : 262)	NC score	0.413936 (rank : 125)
Query Neighborhood Hits	281	Target Neighborhood Hits	276	Shared Neighborhood Hits	182
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

JAM3_MOUSE
θ value	6.88961 (rank : 263)	NC score	0.415377 (rank : 124)
Query Neighborhood Hits	281	Target Neighborhood Hits	286	Shared Neighborhood Hits	176
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

MEGF6_HUMAN
θ value	6.88961 (rank : 264)	NC score	0.031626 (rank : 634)
Query Neighborhood Hits	281	Target Neighborhood Hits	671	Shared Neighborhood Hits	46
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

RELN_MOUSE
θ value	6.88961 (rank : 265)	NC score	0.014697 (rank : 643)
Query Neighborhood Hits	281	Target Neighborhood Hits	235	Shared Neighborhood Hits	14
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

ROR1_MOUSE
θ value	6.88961 (rank : 266)	NC score	0.154562 (rank : 328)
Query Neighborhood Hits	281	Target Neighborhood Hits	1025	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

TICN3_HUMAN
θ value	6.88961 (rank : 267)	NC score	0.121738 (rank : 386)
Query Neighborhood Hits	281	Target Neighborhood Hits	82	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

IGS4B_HUMAN
θ value	8.99809 (rank : 268)	NC score	0.367218 (rank : 149)
Query Neighborhood Hits	281	Target Neighborhood Hits	305	Shared Neighborhood Hits	169
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

IPK1_HUMAN
θ value	8.99809 (rank : 269)	NC score	0.117528 (rank : 394)
Query Neighborhood Hits	281	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

KIRR1_HUMAN
θ value	8.99809 (rank : 270)	NC score	0.416549 (rank : 122)
Query Neighborhood Hits	281	Target Neighborhood Hits	401	Shared Neighborhood Hits	171
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KRA51_HUMAN
θ value	8.99809 (rank : 271)	NC score	0.031396 (rank : 635)
Query Neighborhood Hits	281	Target Neighborhood Hits	288	Shared Neighborhood Hits	17
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LRC21_HUMAN
θ value	8.99809 (rank : 272)	NC score	0.279236 (rank : 184)
Query Neighborhood Hits	281	Target Neighborhood Hits	456	Shared Neighborhood Hits	177
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LU_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.446823 (rank : 105)
Query Neighborhood Hits	281	Target Neighborhood Hits	283	Shared Neighborhood Hits	179
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

LV6A_HUMAN
θ value	8.99809 (rank : 274)	NC score	0.001961 (rank : 646)
Query Neighborhood Hits	281	Target Neighborhood Hits	284	Shared Neighborhood Hits	12
SwissProt Accessions	P01721	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-VI region AR.

MT2_MOUSE
θ value	8.99809 (rank : 275)	NC score	0.030674 (rank : 636)
Query Neighborhood Hits	281	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

PDL2_MOUSE
θ value	8.99809 (rank : 276)	NC score	0.161950 (rank : 313)
Query Neighborhood Hits	281	Target Neighborhood Hits	116	Shared Neighborhood Hits	84
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PGFRA_HUMAN
θ value	8.99809 (rank : 277)	NC score	0.145785 (rank : 347)
Query Neighborhood Hits	281	Target Neighborhood Hits	980	Shared Neighborhood Hits	152
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

SSPO_MOUSE
θ value	8.99809 (rank : 278)	NC score	0.044641 (rank : 629)
Query Neighborhood Hits	281	Target Neighborhood Hits	800	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SYNE1_HUMAN
θ value	8.99809 (rank : 279)	NC score	-0.003796 (rank : 647)
Query Neighborhood Hits	281	Target Neighborhood Hits	1484	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TICN3_MOUSE
θ value	8.99809 (rank : 280)	NC score	0.125081 (rank : 378)
Query Neighborhood Hits	281	Target Neighborhood Hits	83	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

VGFR2_HUMAN
θ value	8.99809 (rank : 281)	NC score	0.232644 (rank : 207)
Query Neighborhood Hits	281	Target Neighborhood Hits	1103	Shared Neighborhood Hits	195
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

A1BG_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.067517 (rank : 505)
Query Neighborhood Hits	281	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	P04217, Q8IYJ6, Q96P39	Gene names	A1BG
Domain Architecture
Description	Alpha-1B-glycoprotein precursor (Alpha-1-B glycoprotein).

A2GL_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.050878 (rank : 615)
Query Neighborhood Hits	281	Target Neighborhood Hits	281	Shared Neighborhood Hits	27
SwissProt Accessions	P02750, Q8N4F5, Q96QZ4	Gene names	LRG1, LRG
Domain Architecture
Description	Leucine-rich alpha-2-glycoprotein precursor (LRG).

AATK_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.051076 (rank : 612)
Query Neighborhood Hits	281	Target Neighborhood Hits	1243	Shared Neighborhood Hits	34
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AATK_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.052304 (rank : 593)
Query Neighborhood Hits	281	Target Neighborhood Hits	942	Shared Neighborhood Hits	33
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ACK1_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.052002 (rank : 596)
Query Neighborhood Hits	281	Target Neighborhood Hits	1140	Shared Neighborhood Hits	36
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.052384 (rank : 590)
Query Neighborhood Hits	281	Target Neighborhood Hits	1080	Shared Neighborhood Hits	35
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ALK_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.055743 (rank : 559)
Query Neighborhood Hits	281	Target Neighborhood Hits	795	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.056265 (rank : 553)
Query Neighborhood Hits	281	Target Neighborhood Hits	811	Shared Neighborhood Hits	35
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALS_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.056639 (rank : 551)
Query Neighborhood Hits	281	Target Neighborhood Hits	280	Shared Neighborhood Hits	27
SwissProt Accessions	P35858	Gene names	IGFALS, ALS
Domain Architecture
Description	Insulin-like growth factor-binding protein complex acid labile chain precursor (ALS).

ALS_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.054528 (rank : 570)
Query Neighborhood Hits	281	Target Neighborhood Hits	275	Shared Neighborhood Hits	26
SwissProt Accessions	P70389, Q9DBI7	Gene names	Igfals, Albs, Als
Domain Architecture
Description	Insulin-like growth factor-binding protein complex acid labile chain precursor (ALS).

AMGO1_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.077188 (rank : 483)
Query Neighborhood Hits	281	Target Neighborhood Hits	353	Shared Neighborhood Hits	76
SwissProt Accessions	Q86WK6, Q8IW71, Q9ULQ7	Gene names	AMIGO1, ALI2, AMIGO, KIAA1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

AMGO1_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.067504 (rank : 506)
Query Neighborhood Hits	281	Target Neighborhood Hits	325	Shared Neighborhood Hits	65
SwissProt Accessions	Q80ZD8, Q69ZQ0, Q8R5D4, Q921U9	Gene names	Amigo1, Ali2, Amigo, Kiaa1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

AMGO2_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.101053 (rank : 417)
Query Neighborhood Hits	281	Target Neighborhood Hits	357	Shared Neighborhood Hits	101
SwissProt Accessions	Q86SJ2, Q7Z4A0, Q96CN8	Gene names	AMIGO2, ALI1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA).

AMGO2_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.092589 (rank : 436)
Query Neighborhood Hits	281	Target Neighborhood Hits	329	Shared Neighborhood Hits	81
SwissProt Accessions	Q80ZD9	Gene names	Amigo2, Ali1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1).

AMGO3_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.093315 (rank : 432)
Query Neighborhood Hits	281	Target Neighborhood Hits	276	Shared Neighborhood Hits	70
SwissProt Accessions	Q86WK7, Q96JH6	Gene names	AMIGO3, ALI3, KIAA1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

AMGO3_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.088168 (rank : 450)
Query Neighborhood Hits	281	Target Neighborhood Hits	276	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C2S7, Q6ZPH1, Q8CEB3	Gene names	Amigo3, Ali3, Kiaa1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

ANKF1_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.085821 (rank : 457)
Query Neighborhood Hits	281	Target Neighborhood Hits	126	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

BASI_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.374180 (rank : 146)
Query Neighborhood Hits	281	Target Neighborhood Hits	211	Shared Neighborhood Hits	157
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

BASI_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.368458 (rank : 148)
Query Neighborhood Hits	281	Target Neighborhood Hits	238	Shared Neighborhood Hits	155
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

BT1A1_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.063145 (rank : 516)
Query Neighborhood Hits	281	Target Neighborhood Hits	322	Shared Neighborhood Hits	83
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.070013 (rank : 499)
Query Neighborhood Hits	281	Target Neighborhood Hits	252	Shared Neighborhood Hits	87
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A2_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.080785 (rank : 476)
Query Neighborhood Hits	281	Target Neighborhood Hits	158	Shared Neighborhood Hits	70
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

BTNL1_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.063109 (rank : 518)
Query Neighborhood Hits	281	Target Neighborhood Hits	151	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

CD166_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.281760 (rank : 180)
Query Neighborhood Hits	281	Target Neighborhood Hits	247	Shared Neighborhood Hits	135
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

CD166_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.303918 (rank : 169)
Query Neighborhood Hits	281	Target Neighborhood Hits	252	Shared Neighborhood Hits	142
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

CD226_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.052328 (rank : 592)
Query Neighborhood Hits	281	Target Neighborhood Hits	87	Shared Neighborhood Hits	39
SwissProt Accessions	Q15762	Gene names	CD226, DNAM1
Domain Architecture
Description	CD226 antigen precursor (DNAX accessory molecule 1) (DNAM-1).

CD22_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.410706 (rank : 131)
Query Neighborhood Hits	281	Target Neighborhood Hits	331	Shared Neighborhood Hits	170
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD244_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.053281 (rank : 583)
Query Neighborhood Hits	281	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZW8, Q96T47, Q9NQD2, Q9NQD3, Q9Y288	Gene names	CD244, 2B4
Domain Architecture
Description	Natural killer cell receptor 2B4 precursor (NKR2B4) (NK cell type I receptor protein 2B4) (h2B4) (CD244 antigen) (NK cell activation- inducing ligand) (NAIL).

CD33_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.055088 (rank : 567)
Query Neighborhood Hits	281	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	P20138, Q8TD24	Gene names	CD33
Domain Architecture
Description	Myeloid cell surface antigen CD33 precursor (Siglec-3) (gp67).

CD33_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.057410 (rank : 550)
Query Neighborhood Hits	281	Target Neighborhood Hits	45	Shared Neighborhood Hits	21
SwissProt Accessions	Q63994, Q63997	Gene names	Cd33
Domain Architecture
Description	Myeloid cell surface antigen CD33 precursor (Siglec-3).

CD45_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.053856 (rank : 578)
Query Neighborhood Hits	281	Target Neighborhood Hits	243	Shared Neighborhood Hits	22
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.055360 (rank : 566)
Query Neighborhood Hits	281	Target Neighborhood Hits	178	Shared Neighborhood Hits	25
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

CD4_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.082700 (rank : 469)
Query Neighborhood Hits	281	Target Neighborhood Hits	122	Shared Neighborhood Hits	43
SwissProt Accessions	P01730, Q4ZGK2, Q5U066	Gene names	CD4
Domain Architecture
Description	T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3).

CD79A_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.126929 (rank : 371)
Query Neighborhood Hits	281	Target Neighborhood Hits	102	Shared Neighborhood Hits	58
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

CD80_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.110896 (rank : 402)
Query Neighborhood Hits	281	Target Neighborhood Hits	136	Shared Neighborhood Hits	70
SwissProt Accessions	Q00609, Q61332	Gene names	Cd80, B7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (B7).

CEA20_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.338577 (rank : 155)
Query Neighborhood Hits	281	Target Neighborhood Hits	251	Shared Neighborhood Hits	149
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

CEAM1_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.316875 (rank : 163)
Query Neighborhood Hits	281	Target Neighborhood Hits	348	Shared Neighborhood Hits	170
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

CEAM1_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.356693 (rank : 151)
Query Neighborhood Hits	281	Target Neighborhood Hits	326	Shared Neighborhood Hits	177
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

CEAM6_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.264517 (rank : 187)
Query Neighborhood Hits	281	Target Neighborhood Hits	308	Shared Neighborhood Hits	170
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

CEAM7_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.124177 (rank : 381)
Query Neighborhood Hits	281	Target Neighborhood Hits	170	Shared Neighborhood Hits	99
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

CEAM8_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.231817 (rank : 209)
Query Neighborhood Hits	281	Target Neighborhood Hits	264	Shared Neighborhood Hits	163
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

CHAD_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.059515 (rank : 530)
Query Neighborhood Hits	281	Target Neighborhood Hits	267	Shared Neighborhood Hits	26
SwissProt Accessions	O15335, Q96RJ5	Gene names	CHAD
Domain Architecture
Description	Chondroadherin precursor (Cartilage leucine-rich protein).

CHAD_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.058182 (rank : 539)
Query Neighborhood Hits	281	Target Neighborhood Hits	260	Shared Neighborhood Hits	26
SwissProt Accessions	O55226	Gene names	Chad
Domain Architecture
Description	Chondroadherin precursor (Cartilage leucine-rich protein).

CILP1_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.200131 (rank : 258)
Query Neighborhood Hits	281	Target Neighborhood Hits	266	Shared Neighborhood Hits	140
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.215413 (rank : 232)
Query Neighborhood Hits	281	Target Neighborhood Hits	282	Shared Neighborhood Hits	149
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CO7A1_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.118788 (rank : 391)
Query Neighborhood Hits	281	Target Neighborhood Hits	807	Shared Neighborhood Hits	74
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COCA1_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.161572 (rank : 314)
Query Neighborhood Hits	281	Target Neighborhood Hits	458	Shared Neighborhood Hits	73
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.172596 (rank : 295)
Query Neighborhood Hits	281	Target Neighborhood Hits	467	Shared Neighborhood Hits	82
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.120391 (rank : 389)
Query Neighborhood Hits	281	Target Neighborhood Hits	427	Shared Neighborhood Hits	63
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.146030 (rank : 345)
Query Neighborhood Hits	281	Target Neighborhood Hits	402	Shared Neighborhood Hits	61
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COKA1_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.112372 (rank : 401)
Query Neighborhood Hits	281	Target Neighborhood Hits	403	Shared Neighborhood Hits	55
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CPN2_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.053829 (rank : 579)
Query Neighborhood Hits	281	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	P22792, Q86SU4, Q8N5V4	Gene names	CPN2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit).

CPN2_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.052731 (rank : 587)
Query Neighborhood Hits	281	Target Neighborhood Hits	291	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBB9, Q8R113	Gene names	Cpn2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit).

CRLF1_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.060554 (rank : 525)
Query Neighborhood Hits	281	Target Neighborhood Hits	122	Shared Neighborhood Hits	34
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

CRLF1_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.051387 (rank : 603)
Query Neighborhood Hits	281	Target Neighborhood Hits	116	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

CSF1R_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.136262 (rank : 357)
Query Neighborhood Hits	281	Target Neighborhood Hits	943	Shared Neighborhood Hits	144
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSF3R_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.127683 (rank : 369)
Query Neighborhood Hits	281	Target Neighborhood Hits	140	Shared Neighborhood Hits	47
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CSF3R_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.110081 (rank : 405)
Query Neighborhood Hits	281	Target Neighborhood Hits	104	Shared Neighborhood Hits	44
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CT075_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.103650 (rank : 415)
Query Neighborhood Hits	281	Target Neighborhood Hits	387	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

CT075_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.082922 (rank : 468)
Query Neighborhood Hits	281	Target Neighborhood Hits	358	Shared Neighborhood Hits	55
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

CXAR_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.225531 (rank : 216)
Query Neighborhood Hits	281	Target Neighborhood Hits	245	Shared Neighborhood Hits	119
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

CXAR_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.223323 (rank : 222)
Query Neighborhood Hits	281	Target Neighborhood Hits	250	Shared Neighborhood Hits	119
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

DDR1_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.054441 (rank : 571)
Query Neighborhood Hits	281	Target Neighborhood Hits	819	Shared Neighborhood Hits	35
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.055557 (rank : 562)
Query Neighborhood Hits	281	Target Neighborhood Hits	818	Shared Neighborhood Hits	35
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.054311 (rank : 572)
Query Neighborhood Hits	281	Target Neighborhood Hits	818	Shared Neighborhood Hits	35
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.053230 (rank : 584)
Query Neighborhood Hits	281	Target Neighborhood Hits	813	Shared Neighborhood Hits	35
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

ECM2_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.050312 (rank : 626)
Query Neighborhood Hits	281	Target Neighborhood Hits	402	Shared Neighborhood Hits	35
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

EMB_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.089483 (rank : 446)
Query Neighborhood Hits	281	Target Neighborhood Hits	54	Shared Neighborhood Hits	36
SwissProt Accessions	Q6PCB8	Gene names	EMB
Domain Architecture	No domain graphic available
Description	Embigin precursor.

EMB_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.177622 (rank : 288)
Query Neighborhood Hits	281	Target Neighborhood Hits	83	Shared Neighborhood Hits	67
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

EPHA1_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.066044 (rank : 510)
Query Neighborhood Hits	281	Target Neighborhood Hits	997	Shared Neighborhood Hits	77
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA1_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.069584 (rank : 500)
Query Neighborhood Hits	281	Target Neighborhood Hits	958	Shared Neighborhood Hits	86
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA2_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.082485 (rank : 470)
Query Neighborhood Hits	281	Target Neighborhood Hits	1021	Shared Neighborhood Hits	88
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA2_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.077949 (rank : 480)
Query Neighborhood Hits	281	Target Neighborhood Hits	1020	Shared Neighborhood Hits	86
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHA3_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.091383 (rank : 441)
Query Neighborhood Hits	281	Target Neighborhood Hits	1005	Shared Neighborhood Hits	102
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHA3_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.092514 (rank : 437)
Query Neighborhood Hits	281	Target Neighborhood Hits	1009	Shared Neighborhood Hits	101
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHA4_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.087369 (rank : 452)
Query Neighborhood Hits	281	Target Neighborhood Hits	975	Shared Neighborhood Hits	89
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA4_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.089187 (rank : 448)
Query Neighborhood Hits	281	Target Neighborhood Hits	982	Shared Neighborhood Hits	91
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA5_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.087701 (rank : 451)
Query Neighborhood Hits	281	Target Neighborhood Hits	1009	Shared Neighborhood Hits	94
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHA5_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.078739 (rank : 478)
Query Neighborhood Hits	281	Target Neighborhood Hits	950	Shared Neighborhood Hits	84
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

EPHA6_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.073805 (rank : 491)
Query Neighborhood Hits	281	Target Neighborhood Hits	959	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA6_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.069012 (rank : 501)
Query Neighborhood Hits	281	Target Neighborhood Hits	946	Shared Neighborhood Hits	72
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA7_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.095320 (rank : 426)
Query Neighborhood Hits	281	Target Neighborhood Hits	1053	Shared Neighborhood Hits	92
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA7_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.093814 (rank : 431)
Query Neighborhood Hits	281	Target Neighborhood Hits	1025	Shared Neighborhood Hits	91
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHA8_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.091942 (rank : 440)
Query Neighborhood Hits	281	Target Neighborhood Hits	956	Shared Neighborhood Hits	94
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA8_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.094203 (rank : 427)
Query Neighborhood Hits	281	Target Neighborhood Hits	969	Shared Neighborhood Hits	96
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

EPHAA_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.073333 (rank : 493)
Query Neighborhood Hits	281	Target Neighborhood Hits	960	Shared Neighborhood Hits	79
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHB1_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.084525 (rank : 460)
Query Neighborhood Hits	281	Target Neighborhood Hits	988	Shared Neighborhood Hits	87
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

EPHB2_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.083724 (rank : 463)
Query Neighborhood Hits	281	Target Neighborhood Hits	983	Shared Neighborhood Hits	85
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.083842 (rank : 462)
Query Neighborhood Hits	281	Target Neighborhood Hits	982	Shared Neighborhood Hits	85
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB3_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.093176 (rank : 434)
Query Neighborhood Hits	281	Target Neighborhood Hits	996	Shared Neighborhood Hits	96
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHB3_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.092758 (rank : 435)
Query Neighborhood Hits	281	Target Neighborhood Hits	996	Shared Neighborhood Hits	95
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EPHB4_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.086613 (rank : 454)
Query Neighborhood Hits	281	Target Neighborhood Hits	1056	Shared Neighborhood Hits	96
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHB4_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.089142 (rank : 449)
Query Neighborhood Hits	281	Target Neighborhood Hits	1013	Shared Neighborhood Hits	91
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHB6_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.097039 (rank : 424)
Query Neighborhood Hits	281	Target Neighborhood Hits	912	Shared Neighborhood Hits	96
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHB6_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.093197 (rank : 433)
Query Neighborhood Hits	281	Target Neighborhood Hits	906	Shared Neighborhood Hits	91
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

FAK1_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.052201 (rank : 594)
Query Neighborhood Hits	281	Target Neighborhood Hits	850	Shared Neighborhood Hits	33
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.051906 (rank : 597)
Query Neighborhood Hits	281	Target Neighborhood Hits	850	Shared Neighborhood Hits	33
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

FAK2_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.051210 (rank : 610)
Query Neighborhood Hits	281	Target Neighborhood Hits	847	Shared Neighborhood Hits	33
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.051133 (rank : 611)
Query Neighborhood Hits	281	Target Neighborhood Hits	851	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FCERA_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.125934 (rank : 375)
Query Neighborhood Hits	281	Target Neighborhood Hits	150	Shared Neighborhood Hits	82
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

FCG2A_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.060882 (rank : 523)
Query Neighborhood Hits	281	Target Neighborhood Hits	92	Shared Neighborhood Hits	39
SwissProt Accessions	P12318	Gene names	FCGR2A, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-a precursor (Fc-gamma RII-a) (FcRII-a) (IgG Fc receptor II-a) (Fc-gamma-RIIa) (CD32 antigen) (CDw32).

FCG2B_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.070373 (rank : 497)
Query Neighborhood Hits	281	Target Neighborhood Hits	116	Shared Neighborhood Hits	44
SwissProt Accessions	P31994, O95649, Q53X85, Q5VXA9, Q8NIA1	Gene names	FCGR2B, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-b precursor (Fc-gamma RII-b) (FcRII-b) (IgG Fc receptor II-b) (Fc-gamma-RIIb) (CD32 antigen) (CDw32).

FCG2C_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.070341 (rank : 498)
Query Neighborhood Hits	281	Target Neighborhood Hits	118	Shared Neighborhood Hits	46
SwissProt Accessions	P31995, O00523, O00524, O00525	Gene names	FCGR2C, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-c precursor (Fc-gamma RII-c) (FcRII-c) (IgG Fc receptor II-c) (Fc-gamma-RIIc) (CD32 antigen) (CDw32).

FCGR1_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.113894 (rank : 399)
Query Neighborhood Hits	281	Target Neighborhood Hits	145	Shared Neighborhood Hits	75
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

FCGR1_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.086741 (rank : 453)
Query Neighborhood Hits	281	Target Neighborhood Hits	123	Shared Neighborhood Hits	60
SwissProt Accessions	P26151	Gene names	Fcgr1, Fcg1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I).

FCRL2_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.320600 (rank : 162)
Query Neighborhood Hits	281	Target Neighborhood Hits	251	Shared Neighborhood Hits	141
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

FCRL5_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.349264 (rank : 153)
Query Neighborhood Hits	281	Target Neighborhood Hits	267	Shared Neighborhood Hits	149
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

FCRLA_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.073835 (rank : 490)
Query Neighborhood Hits	281	Target Neighborhood Hits	135	Shared Neighborhood Hits	41
SwissProt Accessions	Q7L513, Q5VXA1, Q5VXA2, Q5VXA3, Q5VXB0, Q8NEW4, Q8WXH3, Q96PC6, Q96PJ0, Q96PJ1, Q96PJ2, Q96PJ4, Q9BR57	Gene names	FCRLA, FCRL, FCRL1, FCRLM1, FCRX, FREB
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

FCRLA_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.072990 (rank : 494)
Query Neighborhood Hits	281	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q920A9, Q3T9Q2, Q8K3U9, Q8VHP5	Gene names	Fcrla, Fcrl, Fcrl1, Fcrlm1, Fcrx, Freb
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

FINC_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.226548 (rank : 215)
Query Neighborhood Hits	281	Target Neighborhood Hits	302	Shared Neighborhood Hits	89
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.229569 (rank : 211)
Query Neighborhood Hits	281	Target Neighborhood Hits	309	Shared Neighborhood Hits	85
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FLRT1_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.057430 (rank : 549)
Query Neighborhood Hits	281	Target Neighborhood Hits	286	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NZU1	Gene names	FLRT1
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT1 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 1).

FLRT2_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.055542 (rank : 564)
Query Neighborhood Hits	281	Target Neighborhood Hits	295	Shared Neighborhood Hits	27
SwissProt Accessions	O43155	Gene names	FLRT2, KIAA0405
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT2 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 2).

FLRT3_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.054650 (rank : 569)
Query Neighborhood Hits	281	Target Neighborhood Hits	281	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NZU0, Q96K39, Q96K42, Q96KB1, Q9P259	Gene names	FLRT3, KIAA1469
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT3 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 3).

FLT3_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.084145 (rank : 461)
Query Neighborhood Hits	281	Target Neighborhood Hits	843	Shared Neighborhood Hits	70
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

FLT3_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.099995 (rank : 418)
Query Neighborhood Hits	281	Target Neighborhood Hits	847	Shared Neighborhood Hits	80
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

FNDC3_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.322279 (rank : 160)
Query Neighborhood Hits	281	Target Neighborhood Hits	196	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.322505 (rank : 159)
Query Neighborhood Hits	281	Target Neighborhood Hits	207	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FPRP_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.110313 (rank : 404)
Query Neighborhood Hits	281	Target Neighborhood Hits	130	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P2B2, Q8N2K6	Gene names	PTGFRN, CD9P1, FPRP, KIAA1436
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD9 partner 1) (CD9P-1) (CD315 antigen).

FPRP_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.094048 (rank : 430)
Query Neighborhood Hits	281	Target Neighborhood Hits	116	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WV91	Gene names	Ptgfrn, Fprp
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD315 antigen).

GP116_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.058984 (rank : 537)
Query Neighborhood Hits	281	Target Neighborhood Hits	167	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP124_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.054101 (rank : 575)
Query Neighborhood Hits	281	Target Neighborhood Hits	304	Shared Neighborhood Hits	30
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP124_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.053287 (rank : 582)
Query Neighborhood Hits	281	Target Neighborhood Hits	423	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.065622 (rank : 511)
Query Neighborhood Hits	281	Target Neighborhood Hits	327	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP125_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.067341 (rank : 507)
Query Neighborhood Hits	281	Target Neighborhood Hits	329	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP1BA_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.050405 (rank : 625)
Query Neighborhood Hits	281	Target Neighborhood Hits	407	Shared Neighborhood Hits	28
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

GP1BB_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.052414 (rank : 589)
Query Neighborhood Hits	281	Target Neighborhood Hits	136	Shared Neighborhood Hits	26
SwissProt Accessions	P56400	Gene names	Gp1bb
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (CD42c antigen).

GPA33_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.284733 (rank : 176)
Query Neighborhood Hits	281	Target Neighborhood Hits	273	Shared Neighborhood Hits	140
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

GPA33_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.302528 (rank : 170)
Query Neighborhood Hits	281	Target Neighborhood Hits	294	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

GPIX_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.051229 (rank : 608)
Query Neighborhood Hits	281	Target Neighborhood Hits	162	Shared Neighborhood Hits	26
SwissProt Accessions	P14770, Q14445, Q92525	Gene names	GP9
Domain Architecture
Description	Platelet glycoprotein IX precursor (GPIX) (CD42a antigen).

GPV_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.053447 (rank : 581)
Query Neighborhood Hits	281	Target Neighborhood Hits	284	Shared Neighborhood Hits	26
SwissProt Accessions	P40197	Gene names	GP5
Domain Architecture
Description	Platelet glycoprotein V precursor (GPV) (CD42D antigen).

GPV_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.056191 (rank : 555)
Query Neighborhood Hits	281	Target Neighborhood Hits	293	Shared Neighborhood Hits	26
SwissProt Accessions	O08742	Gene names	Gp5
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein V precursor (GPV) (CD42D antigen).

HCFC1_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.055939 (rank : 557)
Query Neighborhood Hits	281	Target Neighborhood Hits	348	Shared Neighborhood Hits	38
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC2_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.092006 (rank : 439)
Query Neighborhood Hits	281	Target Neighborhood Hits	154	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HCFC2_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.143386 (rank : 349)
Query Neighborhood Hits	281	Target Neighborhood Hits	97	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HG2A_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.052791 (rank : 586)
Query Neighborhood Hits	281	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

HG2A_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.060726 (rank : 524)
Query Neighborhood Hits	281	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

HHLA2_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.134749 (rank : 362)
Query Neighborhood Hits	281	Target Neighborhood Hits	140	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

HTRA2_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.200632 (rank : 255)
Query Neighborhood Hits	281	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HTRA2_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.201202 (rank : 253)
Query Neighborhood Hits	281	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

I11RA_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.078962 (rank : 477)
Query Neighborhood Hits	281	Target Neighborhood Hits	138	Shared Neighborhood Hits	47
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

I11RA_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.077110 (rank : 485)
Query Neighborhood Hits	281	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

I11RB_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.082984 (rank : 466)
Query Neighborhood Hits	281	Target Neighborhood Hits	101	Shared Neighborhood Hits	50
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

I12R1_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.085148 (rank : 458)
Query Neighborhood Hits	281	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

I12R1_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.071601 (rank : 496)
Query Neighborhood Hits	281	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

I12R2_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.149758 (rank : 337)
Query Neighborhood Hits	281	Target Neighborhood Hits	163	Shared Neighborhood Hits	47
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I12R2_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.149052 (rank : 338)
Query Neighborhood Hits	281	Target Neighborhood Hits	143	Shared Neighborhood Hits	50
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I27RA_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.058064 (rank : 541)
Query Neighborhood Hits	281	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

IBP6_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.138510 (rank : 355)
Query Neighborhood Hits	281	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP6_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.132431 (rank : 366)
Query Neighborhood Hits	281	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

ICAM1_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.094127 (rank : 429)
Query Neighborhood Hits	281	Target Neighborhood Hits	80	Shared Neighborhood Hits	54
SwissProt Accessions	P05362, Q96B50	Gene names	ICAM1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (Major group rhinovirus receptor) (CD54 antigen).

ICAM1_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.098989 (rank : 419)
Query Neighborhood Hits	281	Target Neighborhood Hits	99	Shared Neighborhood Hits	73
SwissProt Accessions	P13597, Q61828	Gene names	Icam1, Icam-1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (MALA-2).

ICAM3_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.086341 (rank : 455)
Query Neighborhood Hits	281	Target Neighborhood Hits	100	Shared Neighborhood Hits	66
SwissProt Accessions	P32942	Gene names	ICAM3
Domain Architecture
Description	Intercellular adhesion molecule 3 precursor (ICAM-3) (ICAM-R) (CDw50) (CD50 antigen).

ICOSL_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.050630 (rank : 619)
Query Neighborhood Hits	281	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

IGF1R_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.078096 (rank : 479)
Query Neighborhood Hits	281	Target Neighborhood Hits	977	Shared Neighborhood Hits	76
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.077129 (rank : 484)
Query Neighborhood Hits	281	Target Neighborhood Hits	973	Shared Neighborhood Hits	74
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGS21_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.164954 (rank : 306)
Query Neighborhood Hits	281	Target Neighborhood Hits	123	Shared Neighborhood Hits	86
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS21_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.166700 (rank : 304)
Query Neighborhood Hits	281	Target Neighborhood Hits	118	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS4B_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.375763 (rank : 145)
Query Neighborhood Hits	281	Target Neighborhood Hits	328	Shared Neighborhood Hits	175
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

IGSF2_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.104902 (rank : 412)
Query Neighborhood Hits	281	Target Neighborhood Hits	208	Shared Neighborhood Hits	70
SwissProt Accessions	Q93033, Q15856	Gene names	IGSF2, CD101, EWI101, V7
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 2 precursor (Glu-Trp-Ile EWI motif- containing protein 101) (EWI-101) (Cell surface glycoprotein V7) (CD101 antigen).

IL1R1_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.175998 (rank : 289)
Query Neighborhood Hits	281	Target Neighborhood Hits	140	Shared Neighborhood Hits	99
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

IL1R1_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.163660 (rank : 308)
Query Neighborhood Hits	281	Target Neighborhood Hits	142	Shared Neighborhood Hits	99
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

IL1R2_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.235561 (rank : 204)
Query Neighborhood Hits	281	Target Neighborhood Hits	153	Shared Neighborhood Hits	102
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

IL1R2_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.193015 (rank : 269)
Query Neighborhood Hits	281	Target Neighborhood Hits	125	Shared Neighborhood Hits	82
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

IL27B_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.072019 (rank : 495)
Query Neighborhood Hits	281	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

IL6RA_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.068630 (rank : 503)
Query Neighborhood Hits	281	Target Neighborhood Hits	104	Shared Neighborhood Hits	43
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

IL6RB_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.193432 (rank : 268)
Query Neighborhood Hits	281	Target Neighborhood Hits	181	Shared Neighborhood Hits	62
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL6RB_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.178713 (rank : 285)
Query Neighborhood Hits	281	Target Neighborhood Hits	168	Shared Neighborhood Hits	64
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

ILRL1_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.152475 (rank : 330)
Query Neighborhood Hits	281	Target Neighborhood Hits	167	Shared Neighborhood Hits	99
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

ILRL1_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.109805 (rank : 406)
Query Neighborhood Hits	281	Target Neighborhood Hits	172	Shared Neighborhood Hits	98
SwissProt Accessions	P14719, Q05208	Gene names	Il1rl1, Ly84, St2, Ste2
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein) (T1 protein) (Lymphocyte antigen 84).

ILRL2_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.089330 (rank : 447)
Query Neighborhood Hits	281	Target Neighborhood Hits	112	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HB29, Q13525, Q45H74	Gene names	IL1RL2, IL1RRP2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2) (Interleukin-1 receptor-related protein 2) (IL1R-rp2).

ILRL2_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.155293 (rank : 326)
Query Neighborhood Hits	281	Target Neighborhood Hits	158	Shared Neighborhood Hits	111
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

INSRR_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.082197 (rank : 473)
Query Neighborhood Hits	281	Target Neighborhood Hits	950	Shared Neighborhood Hits	69
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.083016 (rank : 465)
Query Neighborhood Hits	281	Target Neighborhood Hits	961	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSR_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.074100 (rank : 489)
Query Neighborhood Hits	281	Target Neighborhood Hits	963	Shared Neighborhood Hits	62
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.077465 (rank : 482)
Query Neighborhood Hits	281	Target Neighborhood Hits	968	Shared Neighborhood Hits	63
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

IPK2_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.052147 (rank : 595)
Query Neighborhood Hits	281	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BMY7	Gene names	Spink2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 2 precursor.

IRPL1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.203113 (rank : 249)
Query Neighborhood Hits	281	Target Neighborhood Hits	196	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

IRPL1_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.208484 (rank : 240)
Query Neighborhood Hits	281	Target Neighborhood Hits	186	Shared Neighborhood Hits	123
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

IRPL2_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.209708 (rank : 237)
Query Neighborhood Hits	281	Target Neighborhood Hits	194	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

IRPL2_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.206779 (rank : 243)
Query Neighborhood Hits	281	Target Neighborhood Hits	195	Shared Neighborhood Hits	115
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

ISK4_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.074244 (rank : 488)
Query Neighborhood Hits	281	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

ISK4_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.055570 (rank : 561)
Query Neighborhood Hits	281	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

ISK5_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.082972 (rank : 467)
Query Neighborhood Hits	281	Target Neighborhood Hits	89	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

ISK7_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.068758 (rank : 502)
Query Neighborhood Hits	281	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

ISK7_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.059418 (rank : 531)
Query Neighborhood Hits	281	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

ITB4_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.185175 (rank : 280)
Query Neighborhood Hits	281	Target Neighborhood Hits	458	Shared Neighborhood Hits	84
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

JAM1_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.410786 (rank : 130)
Query Neighborhood Hits	281	Target Neighborhood Hits	294	Shared Neighborhood Hits	177
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

JAM1_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.385231 (rank : 143)
Query Neighborhood Hits	281	Target Neighborhood Hits	287	Shared Neighborhood Hits	174
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

JAM2_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.388108 (rank : 141)
Query Neighborhood Hits	281	Target Neighborhood Hits	292	Shared Neighborhood Hits	180
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM3_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.412731 (rank : 126)
Query Neighborhood Hits	281	Target Neighborhood Hits	271	Shared Neighborhood Hits	178
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAML1_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.073746 (rank : 492)
Query Neighborhood Hits	281	Target Neighborhood Hits	108	Shared Neighborhood Hits	45
SwissProt Accessions	Q86YT9, Q5DTC6, Q7Z499, Q8N9I7, Q8NF70	Gene names	AMICA1, JAML
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (Dendritic cell-specific protein CREA7-1) (Adhesion molecule interacting with CXADR antigen 1).

JAML1_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.134769 (rank : 361)
Query Neighborhood Hits	281	Target Neighborhood Hits	185	Shared Neighborhood Hits	91
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

KALM_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.169865 (rank : 300)
Query Neighborhood Hits	281	Target Neighborhood Hits	114	Shared Neighborhood Hits	48
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

KSYK_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.051303 (rank : 606)
Query Neighborhood Hits	281	Target Neighborhood Hits	901	Shared Neighborhood Hits	33
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.051363 (rank : 605)
Query Neighborhood Hits	281	Target Neighborhood Hits	944	Shared Neighborhood Hits	35
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LAG3_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.115828 (rank : 397)
Query Neighborhood Hits	281	Target Neighborhood Hits	129	Shared Neighborhood Hits	56
SwissProt Accessions	P18627	Gene names	LAG3, FDC
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (FDC protein) (CD223 antigen).

LAG3_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.124643 (rank : 379)
Query Neighborhood Hits	281	Target Neighborhood Hits	117	Shared Neighborhood Hits	66
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

LCE1A_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.054861 (rank : 568)
Query Neighborhood Hits	281	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.082286 (rank : 471)
Query Neighborhood Hits	281	Target Neighborhood Hits	58	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.098421 (rank : 421)
Query Neighborhood Hits	281	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.091028 (rank : 443)
Query Neighborhood Hits	281	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.102253 (rank : 416)
Query Neighborhood Hits	281	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE4A_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.054033 (rank : 577)
Query Neighborhood Hits	281	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LIFR_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.169027 (rank : 302)
Query Neighborhood Hits	281	Target Neighborhood Hits	130	Shared Neighborhood Hits	49
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

LIFR_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.161466 (rank : 315)
Query Neighborhood Hits	281	Target Neighborhood Hits	127	Shared Neighborhood Hits	50
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

LRC15_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.054125 (rank : 574)
Query Neighborhood Hits	281	Target Neighborhood Hits	305	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TF66, Q7RTN7	Gene names	LRRC15, LIB
Domain Architecture
Description	Leucine-rich repeat-containing protein 15 precursor (hLib).

LRC15_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.055665 (rank : 560)
Query Neighborhood Hits	281	Target Neighborhood Hits	305	Shared Neighborhood Hits	26
SwissProt Accessions	Q80X72	Gene names	Lrrc15
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 15 precursor.

LRC19_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.050836 (rank : 617)
Query Neighborhood Hits	281	Target Neighborhood Hits	238	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BZT5, Q6P8J1	Gene names	Lrrc19
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 19 precursor.

LRC52_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.050240 (rank : 627)
Query Neighborhood Hits	281	Target Neighborhood Hits	229	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N7C0, Q5T9K5	Gene names	LRRC52
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 52 precursor.

LRC55_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.051797 (rank : 599)
Query Neighborhood Hits	281	Target Neighborhood Hits	257	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZSA7	Gene names	LRRC55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

LRC55_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.050548 (rank : 624)
Query Neighborhood Hits	281	Target Neighborhood Hits	254	Shared Neighborhood Hits	26
SwissProt Accessions	Q3UY51	Gene names	Lrrc55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

LRFN5_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.270540 (rank : 186)
Query Neighborhood Hits	281	Target Neighborhood Hits	464	Shared Neighborhood Hits	177
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRFN5_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.275982 (rank : 185)
Query Neighborhood Hits	281	Target Neighborhood Hits	472	Shared Neighborhood Hits	180
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRRC3_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.051239 (rank : 607)
Query Neighborhood Hits	281	Target Neighborhood Hits	236	Shared Neighborhood Hits	26
SwissProt Accessions	P59034	Gene names	Lrrc3
Domain Architecture
Description	Leucine-rich repeat-containing protein 3 precursor.

LRRK1_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.051364 (rank : 604)
Query Neighborhood Hits	281	Target Neighborhood Hits	1237	Shared Neighborhood Hits	59
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

LRRK1_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.053063 (rank : 585)
Query Neighborhood Hits	281	Target Neighborhood Hits	1267	Shared Neighborhood Hits	59
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

LRRN3_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.229331 (rank : 212)
Query Neighborhood Hits	281	Target Neighborhood Hits	455	Shared Neighborhood Hits	167
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRTM1_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.050840 (rank : 616)
Query Neighborhood Hits	281	Target Neighborhood Hits	273	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UE6, Q96DN1	Gene names	LRRTM1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 1 precursor.

LRTM1_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.051905 (rank : 598)
Query Neighborhood Hits	281	Target Neighborhood Hits	264	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K377, Q3UVX1	Gene names	Lrrtm1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 1 precursor.

LRTM2_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.051213 (rank : 609)
Query Neighborhood Hits	281	Target Neighborhood Hits	282	Shared Neighborhood Hits	26
SwissProt Accessions	O43300, Q7L770	Gene names	LRRTM2, KIAA0416, LRRN2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor (Leucine-rich repeat neuronal 2 protein).

LRTM2_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.051459 (rank : 601)
Query Neighborhood Hits	281	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BGA3, Q80U08	Gene names	Lrrtm2, Kiaa0416
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor.

LRTM3_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.050707 (rank : 618)
Query Neighborhood Hits	281	Target Neighborhood Hits	276	Shared Neighborhood Hits	27
SwissProt Accessions	Q86VH5, Q6N0A3	Gene names	LRRTM3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 3 precursor.

LRTM4_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.050629 (rank : 620)
Query Neighborhood Hits	281	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q86VH4	Gene names	LRRTM4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 4 precursor.

LRTM4_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.050890 (rank : 614)
Query Neighborhood Hits	281	Target Neighborhood Hits	284	Shared Neighborhood Hits	28
SwissProt Accessions	Q80XG9, Q8C030, Q8JZS8	Gene names	Lrrtm4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 4 precursor.

LTK_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.057945 (rank : 543)
Query Neighborhood Hits	281	Target Neighborhood Hits	774	Shared Neighborhood Hits	34
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.057673 (rank : 546)
Query Neighborhood Hits	281	Target Neighborhood Hits	770	Shared Neighborhood Hits	34
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LY9_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.059288 (rank : 534)
Query Neighborhood Hits	281	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q01965, Q9ES29, Q9ES35, Q9ES36	Gene names	Ly9, Ly-9
Domain Architecture
Description	T-lymphocyte surface antigen Ly-9 precursor (Lymphocyte antigen 9) (Cell-surface molecule Ly-9).

MALT1_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.431044 (rank : 109)
Query Neighborhood Hits	281	Target Neighborhood Hits	236	Shared Neighborhood Hits	155
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

MERTK_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.153299 (rank : 329)
Query Neighborhood Hits	281	Target Neighborhood Hits	988	Shared Neighborhood Hits	147
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MERTK_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.150174 (rank : 335)
Query Neighborhood Hits	281	Target Neighborhood Hits	974	Shared Neighborhood Hits	144
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MFAP3_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.126451 (rank : 372)
Query Neighborhood Hits	281	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	P55082, Q9NXA7	Gene names	MFAP3
Domain Architecture
Description	Microfibril-associated glycoprotein 3 precursor.

MFAP3_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.117970 (rank : 392)
Query Neighborhood Hits	281	Target Neighborhood Hits	97	Shared Neighborhood Hits	73
SwissProt Accessions	Q922T2, Q8BHK5	Gene names	Mfap3
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 3 precursor.

MOX2R_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.086228 (rank : 456)
Query Neighborhood Hits	281	Target Neighborhood Hits	51	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TD46, Q8TD44, Q8TD45, Q8TD52	Gene names	CD200R1, CD200R, CRTR2, MOX2R, OX2R
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

MOX2R_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.196508 (rank : 263)
Query Neighborhood Hits	281	Target Neighborhood Hits	110	Shared Neighborhood Hits	79
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

NOV_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.123080 (rank : 383)
Query Neighborhood Hits	281	Target Neighborhood Hits	130	Shared Neighborhood Hits	38
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NPHN_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.463729 (rank : 95)
Query Neighborhood Hits	281	Target Neighborhood Hits	370	Shared Neighborhood Hits	184
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NTRK1_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.098712 (rank : 420)
Query Neighborhood Hits	281	Target Neighborhood Hits	1023	Shared Neighborhood Hits	127
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

NTRK2_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.157917 (rank : 323)
Query Neighborhood Hits	281	Target Neighborhood Hits	1081	Shared Neighborhood Hits	178
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.158044 (rank : 322)
Query Neighborhood Hits	281	Target Neighborhood Hits	1088	Shared Neighborhood Hits	179
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK3_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.159303 (rank : 317)
Query Neighborhood Hits	281	Target Neighborhood Hits	1115	Shared Neighborhood Hits	176
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

NYX_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.059192 (rank : 535)
Query Neighborhood Hits	281	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	Q9GZU5, Q5H983, Q9H4J0	Gene names	NYX, CLRP
Domain Architecture
Description	Nyctalopin precursor.

NYX_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.060526 (rank : 526)
Query Neighborhood Hits	281	Target Neighborhood Hits	241	Shared Neighborhood Hits	26
SwissProt Accessions	P83503, Q8BYN4	Gene names	Nyx
Domain Architecture
Description	Nyctalopin precursor.

OX2G_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.112481 (rank : 400)
Query Neighborhood Hits	281	Target Neighborhood Hits	100	Shared Neighborhood Hits	59
SwissProt Accessions	P41217, Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3	Gene names	CD200, MOX2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (CD200 antigen).

OX2G_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.123350 (rank : 382)
Query Neighborhood Hits	281	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O54901, O54816, Q9JHD5	Gene names	Cd200, Mox2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen).

PDL1_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.180705 (rank : 282)
Query Neighborhood Hits	281	Target Neighborhood Hits	195	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL1_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.157330 (rank : 324)
Query Neighborhood Hits	281	Target Neighborhood Hits	168	Shared Neighborhood Hits	92
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.122282 (rank : 385)
Query Neighborhood Hits	281	Target Neighborhood Hits	114	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PECA1_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.179217 (rank : 284)
Query Neighborhood Hits	281	Target Neighborhood Hits	178	Shared Neighborhood Hits	103
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

PECA1_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.145956 (rank : 346)
Query Neighborhood Hits	281	Target Neighborhood Hits	126	Shared Neighborhood Hits	72
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

PGFRA_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.143061 (rank : 350)
Query Neighborhood Hits	281	Target Neighborhood Hits	975	Shared Neighborhood Hits	152
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRB_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.130887 (rank : 368)
Query Neighborhood Hits	281	Target Neighborhood Hits	962	Shared Neighborhood Hits	144
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRB_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.140222 (rank : 353)
Query Neighborhood Hits	281	Target Neighborhood Hits	960	Shared Neighborhood Hits	145
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRL_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.175989 (rank : 290)
Query Neighborhood Hits	281	Target Neighborhood Hits	115	Shared Neighborhood Hits	92
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

PGFRL_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.149837 (rank : 336)
Query Neighborhood Hits	281	Target Neighborhood Hits	106	Shared Neighborhood Hits	81
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

PIGR_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.175362 (rank : 291)
Query Neighborhood Hits	281	Target Neighborhood Hits	164	Shared Neighborhood Hits	85
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

PIGR_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.189791 (rank : 274)
Query Neighborhood Hits	281	Target Neighborhood Hits	214	Shared Neighborhood Hits	107
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

PKD1_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.051676 (rank : 600)
Query Neighborhood Hits	281	Target Neighborhood Hits	387	Shared Neighborhood Hits	31
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

PSG10_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.193988 (rank : 266)
Query Neighborhood Hits	281	Target Neighborhood Hits	227	Shared Neighborhood Hits	139
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

PSG1_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.204390 (rank : 246)
Query Neighborhood Hits	281	Target Neighborhood Hits	232	Shared Neighborhood Hits	148
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

PSG2_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.202756 (rank : 250)
Query Neighborhood Hits	281	Target Neighborhood Hits	229	Shared Neighborhood Hits	147
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

PSG3_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.220148 (rank : 227)
Query Neighborhood Hits	281	Target Neighborhood Hits	242	Shared Neighborhood Hits	150
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

PSG4_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.221223 (rank : 226)
Query Neighborhood Hits	281	Target Neighborhood Hits	243	Shared Neighborhood Hits	149
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

PSG5_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.179233 (rank : 283)
Query Neighborhood Hits	281	Target Neighborhood Hits	231	Shared Neighborhood Hits	140
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

PSG6_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.197715 (rank : 260)
Query Neighborhood Hits	281	Target Neighborhood Hits	231	Shared Neighborhood Hits	140
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

PSG7_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.211158 (rank : 235)
Query Neighborhood Hits	281	Target Neighborhood Hits	239	Shared Neighborhood Hits	152
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

PSG8_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.216282 (rank : 231)
Query Neighborhood Hits	281	Target Neighborhood Hits	239	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

PSG9_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.185420 (rank : 278)
Query Neighborhood Hits	281	Target Neighborhood Hits	221	Shared Neighborhood Hits	140
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

PTPRB_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.076285 (rank : 486)
Query Neighborhood Hits	281	Target Neighborhood Hits	242	Shared Neighborhood Hits	46
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.066674 (rank : 508)
Query Neighborhood Hits	281	Target Neighborhood Hits	207	Shared Neighborhood Hits	35
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.066156 (rank : 509)
Query Neighborhood Hits	281	Target Neighborhood Hits	188	Shared Neighborhood Hits	32
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.119477 (rank : 390)
Query Neighborhood Hits	281	Target Neighborhood Hits	228	Shared Neighborhood Hits	73
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.120727 (rank : 388)
Query Neighborhood Hits	281	Target Neighborhood Hits	223	Shared Neighborhood Hits	73
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.152440 (rank : 331)
Query Neighborhood Hits	281	Target Neighborhood Hits	244	Shared Neighborhood Hits	83
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.148569 (rank : 340)
Query Neighborhood Hits	281	Target Neighborhood Hits	238	Shared Neighborhood Hits	83
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRO_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.064699 (rank : 512)
Query Neighborhood Hits	281	Target Neighborhood Hits	139	Shared Neighborhood Hits	26
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRT_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.134144 (rank : 364)
Query Neighborhood Hits	281	Target Neighborhood Hits	217	Shared Neighborhood Hits	63
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 559)	NC score	0.135038 (rank : 360)
Query Neighborhood Hits	281	Target Neighborhood Hits	219	Shared Neighborhood Hits	65
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.121168 (rank : 387)
Query Neighborhood Hits	281	Target Neighborhood Hits	237	Shared Neighborhood Hits	79
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRV_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.064302 (rank : 513)
Query Neighborhood Hits	281	Target Neighborhood Hits	179	Shared Neighborhood Hits	35
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PVRL1_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.188524 (rank : 275)
Query Neighborhood Hits	281	Target Neighborhood Hits	219	Shared Neighborhood Hits	114
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

PVRL1_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.162252 (rank : 311)
Query Neighborhood Hits	281	Target Neighborhood Hits	201	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

PVRL2_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.132785 (rank : 365)
Query Neighborhood Hits	281	Target Neighborhood Hits	185	Shared Neighborhood Hits	85
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

PVRL2_MOUSE
θ value	θ > 10 (rank : 565)	NC score	0.141591 (rank : 351)
Query Neighborhood Hits	281	Target Neighborhood Hits	242	Shared Neighborhood Hits	88
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

PVRL3_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.185416 (rank : 279)
Query Neighborhood Hits	281	Target Neighborhood Hits	204	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

PVRL3_MOUSE
θ value	θ > 10 (rank : 567)	NC score	0.194965 (rank : 265)
Query Neighborhood Hits	281	Target Neighborhood Hits	212	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

PVR_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.158853 (rank : 320)
Query Neighborhood Hits	281	Target Neighborhood Hits	195	Shared Neighborhood Hits	97
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

R4RL1_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.056210 (rank : 554)
Query Neighborhood Hits	281	Target Neighborhood Hits	240	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UN2, Q8ND46	Gene names	RTN4RL1, NGRH2, NGRL2
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 1 precursor (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3) (Nogo receptor-like 2).

R4RL1_MOUSE
θ value	θ > 10 (rank : 570)	NC score	0.053694 (rank : 580)
Query Neighborhood Hits	281	Target Neighborhood Hits	235	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K0S5	Gene names	Rtn4rl1, Ngrl2
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 1 precursor (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3) (Nogo receptor-like 2).

R4RL2_HUMAN
θ value	θ > 10 (rank : 571)	NC score	0.058117 (rank : 540)
Query Neighborhood Hits	281	Target Neighborhood Hits	273	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UN3, Q6X813	Gene names	RTN4RL2, NGRH1, NGRL3
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 2 precursor (Nogo-66 receptor homolog 1) (Nogo-66 receptor-related protein 2) (NgR2) (Nogo receptor-like 3).

R4RL2_MOUSE
θ value	θ > 10 (rank : 572)	NC score	0.057943 (rank : 544)
Query Neighborhood Hits	281	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q7M6Z0, Q3UQ62	Gene names	Rtn4rl2, Ngrl3
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 2 precursor (Nogo-66 receptor homolog 1) (Nogo-66 receptor-related protein 2) (NgR2) (Nogo receptor-like 3).

RET_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.059321 (rank : 533)
Query Neighborhood Hits	281	Target Neighborhood Hits	873	Shared Neighborhood Hits	32
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.059519 (rank : 529)
Query Neighborhood Hits	281	Target Neighborhood Hits	884	Shared Neighborhood Hits	35
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RIMB2_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.082073 (rank : 474)
Query Neighborhood Hits	281	Target Neighborhood Hits	263	Shared Neighborhood Hits	37
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.077933 (rank : 481)
Query Neighborhood Hits	281	Target Neighborhood Hits	246	Shared Neighborhood Hits	32
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RON_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.050567 (rank : 623)
Query Neighborhood Hits	281	Target Neighborhood Hits	842	Shared Neighborhood Hits	35
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 578)	NC score	0.050617 (rank : 621)
Query Neighborhood Hits	281	Target Neighborhood Hits	836	Shared Neighborhood Hits	33
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.154695 (rank : 327)
Query Neighborhood Hits	281	Target Neighborhood Hits	1018	Shared Neighborhood Hits	178
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROS_HUMAN
θ value	θ > 10 (rank : 580)	NC score	0.104860 (rank : 413)
Query Neighborhood Hits	281	Target Neighborhood Hits	907	Shared Neighborhood Hits	92
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

RTN4R_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.057792 (rank : 545)
Query Neighborhood Hits	281	Target Neighborhood Hits	271	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZR6	Gene names	RTN4R, NOGOR
Domain Architecture
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

RTN4R_MOUSE
θ value	θ > 10 (rank : 582)	NC score	0.055397 (rank : 565)
Query Neighborhood Hits	281	Target Neighborhood Hits	293	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PI8, Q80WQ1	Gene names	Rtn4r, Nogor
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

RYK_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.058315 (rank : 538)
Query Neighborhood Hits	281	Target Neighborhood Hits	701	Shared Neighborhood Hits	31
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.057520 (rank : 548)
Query Neighborhood Hits	281	Target Neighborhood Hits	715	Shared Neighborhood Hits	30
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

SHPS1_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.108104 (rank : 409)
Query Neighborhood Hits	281	Target Neighborhood Hits	455	Shared Neighborhood Hits	87
SwissProt Accessions	P78324, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9	Gene names	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (Sirp-alpha-2) (Sirp-alpha- 3) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusion receptor) (p84) (CD172a antigen).

SHPS1_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.064012 (rank : 514)
Query Neighborhood Hits	281	Target Neighborhood Hits	439	Shared Neighborhood Hits	68
SwissProt Accessions	P97797, O08907, O35924, O88555, O88556, P97796, Q8R559, Q9QX57, Q9WTN4	Gene names	Sirpa, Bit, Myd1, Ptpns1, Shps1, Sirp
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (p84) (CD172a antigen).

SIG10_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.372021 (rank : 147)
Query Neighborhood Hits	281	Target Neighborhood Hits	363	Shared Neighborhood Hits	171
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

SIGL5_MOUSE
θ value	θ > 10 (rank : 588)	NC score	0.293059 (rank : 173)
Query Neighborhood Hits	281	Target Neighborhood Hits	271	Shared Neighborhood Hits	167
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

SIGL6_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.227660 (rank : 213)
Query Neighborhood Hits	281	Target Neighborhood Hits	233	Shared Neighborhood Hits	148
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

SIGL7_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.178443 (rank : 287)
Query Neighborhood Hits	281	Target Neighborhood Hits	180	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y286, Q9NZQ1, Q9UJ86, Q9UJ87, Q9Y502	Gene names	SIGLEC7, AIRM1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 7 precursor (Siglec-7) (QA79 membrane protein) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (p75) (D-siglec) (CDw328 antigen).

SIGL9_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.083192 (rank : 464)
Query Neighborhood Hits	281	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y336, Q9BYI9	Gene names	SIGLEC9
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 9 precursor (Siglec-9) (Protein FOAP-9).

SIRB1_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.092082 (rank : 438)
Query Neighborhood Hits	281	Target Neighborhood Hits	422	Shared Neighborhood Hits	77
SwissProt Accessions	O00241, Q5TFR0, Q8TB12, Q9H1U5, Q9Y4V0	Gene names	SIRPB1
Domain Architecture
Description	Signal-regulatory protein beta-1 precursor (SIRP-beta-1) (CD172b antigen).

SIRPG_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.063122 (rank : 517)
Query Neighborhood Hits	281	Target Neighborhood Hits	359	Shared Neighborhood Hits	64
SwissProt Accessions	Q9P1W8, Q8WWA5, Q9NQK8	Gene names	SIRPG, SIRPB2
Domain Architecture
Description	Signal-regulatory protein gamma precursor (Signal-regulatory protein beta-2) (SIRP-beta-2) (SIRP-b2) (CD172g antigen).

SLIT1_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.057999 (rank : 542)
Query Neighborhood Hits	281	Target Neighborhood Hits	700	Shared Neighborhood Hits	56
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	θ > 10 (rank : 595)	NC score	0.057659 (rank : 547)
Query Neighborhood Hits	281	Target Neighborhood Hits	715	Shared Neighborhood Hits	55
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.059070 (rank : 536)
Query Neighborhood Hits	281	Target Neighborhood Hits	708	Shared Neighborhood Hits	58
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	θ > 10 (rank : 597)	NC score	0.059372 (rank : 532)
Query Neighborhood Hits	281	Target Neighborhood Hits	684	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.056553 (rank : 552)
Query Neighborhood Hits	281	Target Neighborhood Hits	682	Shared Neighborhood Hits	49
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.056175 (rank : 556)
Query Neighborhood Hits	281	Target Neighborhood Hits	700	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SORL_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.125370 (rank : 376)
Query Neighborhood Hits	281	Target Neighborhood Hits	440	Shared Neighborhood Hits	74
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.123041 (rank : 384)
Query Neighborhood Hits	281	Target Neighborhood Hits	439	Shared Neighborhood Hits	72
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SPRC_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.060323 (rank : 528)
Query Neighborhood Hits	281	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
θ value	θ > 10 (rank : 603)	NC score	0.060370 (rank : 527)
Query Neighborhood Hits	281	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SRMS_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.051065 (rank : 613)
Query Neighborhood Hits	281	Target Neighborhood Hits	946	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	θ > 10 (rank : 605)	NC score	0.050576 (rank : 622)
Query Neighborhood Hits	281	Target Neighborhood Hits	964	Shared Neighborhood Hits	33
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

STYK1_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.062915 (rank : 519)
Query Neighborhood Hits	281	Target Neighborhood Hits	786	Shared Neighborhood Hits	35
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

STYK1_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.063235 (rank : 515)
Query Neighborhood Hits	281	Target Neighborhood Hits	779	Shared Neighborhood Hits	33
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

TARSH_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.110696 (rank : 403)
Query Neighborhood Hits	281	Target Neighborhood Hits	768	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TENA_HUMAN
θ value	θ > 10 (rank : 609)	NC score	0.105480 (rank : 411)
Query Neighborhood Hits	281	Target Neighborhood Hits	631	Shared Neighborhood Hits	96
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 610)	NC score	0.097270 (rank : 423)
Query Neighborhood Hits	281	Target Neighborhood Hits	596	Shared Neighborhood Hits	93
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.116528 (rank : 396)
Query Neighborhood Hits	281	Target Neighborhood Hits	453	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 612)	NC score	0.135666 (rank : 358)
Query Neighborhood Hits	281	Target Neighborhood Hits	484	Shared Neighborhood Hits	85
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.132100 (rank : 367)
Query Neighborhood Hits	281	Target Neighborhood Hits	526	Shared Neighborhood Hits	90
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.126020 (rank : 373)
Query Neighborhood Hits	281	Target Neighborhood Hits	531	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENX_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.115622 (rank : 398)
Query Neighborhood Hits	281	Target Neighborhood Hits	789	Shared Neighborhood Hits	105
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TIE1_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.117871 (rank : 393)
Query Neighborhood Hits	281	Target Neighborhood Hits	1241	Shared Neighborhood Hits	132
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.124180 (rank : 380)
Query Neighborhood Hits	281	Target Neighborhood Hits	1266	Shared Neighborhood Hits	150
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.108360 (rank : 408)
Query Neighborhood Hits	281	Target Neighborhood Hits	1192	Shared Neighborhood Hits	115
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.109079 (rank : 407)
Query Neighborhood Hits	281	Target Neighborhood Hits	1204	Shared Neighborhood Hits	113
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TMM25_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.055918 (rank : 558)
Query Neighborhood Hits	281	Target Neighborhood Hits	43	Shared Neighborhood Hits	32
SwissProt Accessions	Q86YD3, Q6UW89, Q86UA7, Q96KA6, Q96MW9	Gene names	TMEM25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

TMM25_MOUSE
θ value	θ > 10 (rank : 621)	NC score	0.062193 (rank : 520)
Query Neighborhood Hits	281	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DCF1, Q3TMP3, Q6PAK7	Gene names	Tmem25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

TNK1_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.052352 (rank : 591)
Query Neighborhood Hits	281	Target Neighborhood Hits	815	Shared Neighborhood Hits	33
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TNK1_MOUSE
θ value	θ > 10 (rank : 623)	NC score	0.051440 (rank : 602)
Query Neighborhood Hits	281	Target Neighborhood Hits	806	Shared Neighborhood Hits	34
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TPBG_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.055551 (rank : 563)
Query Neighborhood Hits	281	Target Neighborhood Hits	238	Shared Neighborhood Hits	26
SwissProt Accessions	Q13641	Gene names	TPBG, 5T4
Domain Architecture	No domain graphic available
Description	Trophoblast glycoprotein precursor (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (5T4 oncofetal antigen) (M6P1).

TPBG_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.052616 (rank : 588)
Query Neighborhood Hits	281	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0L0, Q6PE98, Q8BQA4	Gene names	Tpbg, 5t4
Domain Architecture	No domain graphic available
Description	Trophoblast glycoprotein precursor (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein).

TPSNR_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.075264 (rank : 487)
Query Neighborhood Hits	281	Target Neighborhood Hits	330	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BX59, Q9NWB8	Gene names	TAPBPL
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

TPSNR_MOUSE
θ value	θ > 10 (rank : 627)	NC score	0.081807 (rank : 475)
Query Neighborhood Hits	281	Target Neighborhood Hits	336	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VD31	Gene names	Tapbpl
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

TSK_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.054226 (rank : 573)
Query Neighborhood Hits	281	Target Neighborhood Hits	268	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WUA8, Q6UXK1, Q9UG10, Q9UJX9	Gene names	LRRC54, E2IG4, TSK
Domain Architecture	No domain graphic available
Description	Tsukushi precursor (Leucine-rich repeat-containing protein 54) (E2- induced gene 4 protein).

UFO_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.148137 (rank : 341)
Query Neighborhood Hits	281	Target Neighborhood Hits	981	Shared Neighborhood Hits	145
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

UNC5A_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.167454 (rank : 303)
Query Neighborhood Hits	281	Target Neighborhood Hits	198	Shared Neighborhood Hits	103
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5A_MOUSE
θ value	θ > 10 (rank : 631)	NC score	0.149004 (rank : 339)
Query Neighborhood Hits	281	Target Neighborhood Hits	203	Shared Neighborhood Hits	101
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.162935 (rank : 309)
Query Neighborhood Hits	281	Target Neighborhood Hits	225	Shared Neighborhood Hits	114
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.159179 (rank : 318)
Query Neighborhood Hits	281	Target Neighborhood Hits	226	Shared Neighborhood Hits	118
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.169619 (rank : 301)
Query Neighborhood Hits	281	Target Neighborhood Hits	226	Shared Neighborhood Hits	113
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5D_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.217600 (rank : 228)
Query Neighborhood Hits	281	Target Neighborhood Hits	267	Shared Neighborhood Hits	148
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.221951 (rank : 224)
Query Neighborhood Hits	281	Target Neighborhood Hits	268	Shared Neighborhood Hits	148
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

USH2A_HUMAN
θ value	θ > 10 (rank : 637)	NC score	0.197336 (rank : 261)
Query Neighborhood Hits	281	Target Neighborhood Hits	600	Shared Neighborhood Hits	94
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.187673 (rank : 277)
Query Neighborhood Hits	281	Target Neighborhood Hits	626	Shared Neighborhood Hits	91
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VASN_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.061753 (rank : 521)
Query Neighborhood Hits	281	Target Neighborhood Hits	449	Shared Neighborhood Hits	38
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VASN_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.061247 (rank : 522)
Query Neighborhood Hits	281	Target Neighborhood Hits	426	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VCAM1_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.456002 (rank : 101)
Query Neighborhood Hits	281	Target Neighborhood Hits	352	Shared Neighborhood Hits	189
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

VCAM1_MOUSE
θ value	θ > 10 (rank : 642)	NC score	0.458809 (rank : 98)
Query Neighborhood Hits	281	Target Neighborhood Hits	320	Shared Neighborhood Hits	188
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

VGFR3_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.191821 (rank : 271)
Query Neighborhood Hits	281	Target Neighborhood Hits	1037	Shared Neighborhood Hits	176
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VGFR3_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.191729 (rank : 272)
Query Neighborhood Hits	281	Target Neighborhood Hits	1056	Shared Neighborhood Hits	186
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VSIG4_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.308546 (rank : 166)
Query Neighborhood Hits	281	Target Neighborhood Hits	236	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

WISP1_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.089611 (rank : 445)
Query Neighborhood Hits	281	Target Neighborhood Hits	121	Shared Neighborhood Hits	29
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP1_MOUSE
θ value	θ > 10 (rank : 647)	NC score	0.104231 (rank : 414)
Query Neighborhood Hits	281	Target Neighborhood Hits	123	Shared Neighborhood Hits	33
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

ZAP70_MOUSE
θ value	θ > 10 (rank : 648)	NC score	0.050030 (rank : 628)
Query Neighborhood Hits	281	Target Neighborhood Hits	905	Shared Neighborhood Hits	33
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

Hits sorted by NC score

KAZD1_MOUSE
NC score	0.999962 (rank : 1)	θ value	5.55514e-167 (rank : 1)
Query Neighborhood Hits	281	Target Neighborhood Hits	281	Shared Neighborhood Hits	281
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KAZD1_HUMAN
NC score	0.980104 (rank : 2)	θ value	1.05497e-141 (rank : 2)
Query Neighborhood Hits	281	Target Neighborhood Hits	248	Shared Neighborhood Hits	230
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

IBP7_HUMAN
NC score	0.875641 (rank : 3)	θ value	2.04573e-44 (rank : 3)
Query Neighborhood Hits	281	Target Neighborhood Hits	220	Shared Neighborhood Hits	187
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IBP7_MOUSE
NC score	0.871216 (rank : 4)	θ value	1.01529e-43 (rank : 4)
Query Neighborhood Hits	281	Target Neighborhood Hits	230	Shared Neighborhood Hits	186
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

OBSL1_HUMAN
NC score	0.651657 (rank : 5)	θ value	3.29651e-10 (rank : 11)
Query Neighborhood Hits	281	Target Neighborhood Hits	354	Shared Neighborhood Hits	199
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

PUNC_HUMAN
NC score	0.613503 (rank : 6)	θ value	3.41135e-07 (rank : 22)
Query Neighborhood Hits	281	Target Neighborhood Hits	449	Shared Neighborhood Hits	199
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ROBO2_HUMAN
NC score	0.612272 (rank : 7)	θ value	3.08544e-08 (rank : 15)
Query Neighborhood Hits	281	Target Neighborhood Hits	479	Shared Neighborhood Hits	200
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO1_HUMAN
NC score	0.611825 (rank : 8)	θ value	1.17247e-07 (rank : 17)
Query Neighborhood Hits	281	Target Neighborhood Hits	529	Shared Neighborhood Hits	201
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

PUNC_MOUSE
NC score	0.611487 (rank : 9)	θ value	7.59969e-07 (rank : 25)
Query Neighborhood Hits	281	Target Neighborhood Hits	501	Shared Neighborhood Hits	202
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ROBO3_MOUSE
NC score	0.610892 (rank : 10)	θ value	1.17247e-07 (rank : 19)
Query Neighborhood Hits	281	Target Neighborhood Hits	524	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

ROBO2_MOUSE
NC score	0.610298 (rank : 11)	θ value	4.45536e-07 (rank : 24)
Query Neighborhood Hits	281	Target Neighborhood Hits	504	Shared Neighborhood Hits	200
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO1_MOUSE
NC score	0.609795 (rank : 12)	θ value	1.17247e-07 (rank : 18)
Query Neighborhood Hits	281	Target Neighborhood Hits	559	Shared Neighborhood Hits	201
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

ROBO3_HUMAN
NC score	0.606517 (rank : 13)	θ value	2.61198e-07 (rank : 21)
Query Neighborhood Hits	281	Target Neighborhood Hits	570	Shared Neighborhood Hits	202
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

MYPN_HUMAN
NC score	0.595544 (rank : 14)	θ value	0.00390308 (rank : 94)
Query Neighborhood Hits	281	Target Neighborhood Hits	418	Shared Neighborhood Hits	198
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

NEO1_MOUSE
NC score	0.593017 (rank : 15)	θ value	1.47974e-10 (rank : 10)
Query Neighborhood Hits	281	Target Neighborhood Hits	523	Shared Neighborhood Hits	199
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

DCC_HUMAN
NC score	0.592969 (rank : 16)	θ value	8.11959e-09 (rank : 13)
Query Neighborhood Hits	281	Target Neighborhood Hits	583	Shared Neighborhood Hits	203
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

MYPN_MOUSE
NC score	0.591303 (rank : 17)	θ value	0.00298849 (rank : 89)
Query Neighborhood Hits	281	Target Neighborhood Hits	421	Shared Neighborhood Hits	197
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

NEO1_HUMAN
NC score	0.589174 (rank : 18)	θ value	1.133e-10 (rank : 9)
Query Neighborhood Hits	281	Target Neighborhood Hits	530	Shared Neighborhood Hits	198
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

MYOTI_HUMAN
NC score	0.587022 (rank : 19)	θ value	0.00134147 (rank : 70)
Query Neighborhood Hits	281	Target Neighborhood Hits	292	Shared Neighborhood Hits	196
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

MYOTI_MOUSE
NC score	0.586085 (rank : 20)	θ value	0.00035302 (rank : 52)
Query Neighborhood Hits	281	Target Neighborhood Hits	297	Shared Neighborhood Hits	187
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

FGRL1_HUMAN
NC score	0.585672 (rank : 21)	θ value	0.21417 (rank : 170)
Query Neighborhood Hits	281	Target Neighborhood Hits	335	Shared Neighborhood Hits	198
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

DCC_MOUSE
NC score	0.583801 (rank : 22)	θ value	6.21693e-09 (rank : 12)
Query Neighborhood Hits	281	Target Neighborhood Hits	896	Shared Neighborhood Hits	203
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DSCL1_HUMAN
NC score	0.583461 (rank : 23)	θ value	8.97725e-08 (rank : 16)
Query Neighborhood Hits	281	Target Neighborhood Hits	589	Shared Neighborhood Hits	207
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

FGRL1_MOUSE
NC score	0.582815 (rank : 24)	θ value	0.62314 (rank : 192)
Query Neighborhood Hits	281	Target Neighborhood Hits	325	Shared Neighborhood Hits	199
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

DSCAM_HUMAN
NC score	0.578942 (rank : 25)	θ value	2.44474e-05 (rank : 37)
Query Neighborhood Hits	281	Target Neighborhood Hits	524	Shared Neighborhood Hits	206
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

NFASC_MOUSE
NC score	0.574725 (rank : 26)	θ value	1.43324e-05 (rank : 33)
Query Neighborhood Hits	281	Target Neighborhood Hits	475	Shared Neighborhood Hits	201
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

NCA12_HUMAN
NC score	0.572864 (rank : 27)	θ value	5.44631e-05 (rank : 43)
Query Neighborhood Hits	281	Target Neighborhood Hits	437	Shared Neighborhood Hits	203
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

BOC_HUMAN
NC score	0.572672 (rank : 28)	θ value	0.0113563 (rank : 114)
Query Neighborhood Hits	281	Target Neighborhood Hits	543	Shared Neighborhood Hits	204
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

BOC_MOUSE
NC score	0.572542 (rank : 29)	θ value	0.00298849 (rank : 82)
Query Neighborhood Hits	281	Target Neighborhood Hits	433	Shared Neighborhood Hits	202
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

NCA11_HUMAN
NC score	0.570873 (rank : 30)	θ value	5.44631e-05 (rank : 41)
Query Neighborhood Hits	281	Target Neighborhood Hits	443	Shared Neighborhood Hits	203
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

NFASC_HUMAN
NC score	0.570531 (rank : 31)	θ value	1.87187e-05 (rank : 35)
Query Neighborhood Hits	281	Target Neighborhood Hits	497	Shared Neighborhood Hits	201
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NCA12_MOUSE
NC score	0.569177 (rank : 32)	θ value	5.44631e-05 (rank : 44)
Query Neighborhood Hits	281	Target Neighborhood Hits	399	Shared Neighborhood Hits	203
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

ROBO4_MOUSE
NC score	0.566584 (rank : 33)	θ value	0.000786445 (rank : 63)
Query Neighborhood Hits	281	Target Neighborhood Hits	358	Shared Neighborhood Hits	181
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

CDON_MOUSE
NC score	0.565970 (rank : 34)	θ value	0.0330416 (rank : 135)
Query Neighborhood Hits	281	Target Neighborhood Hits	410	Shared Neighborhood Hits	200
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

ROBO4_HUMAN
NC score	0.564773 (rank : 35)	θ value	0.00869519 (rank : 113)
Query Neighborhood Hits	281	Target Neighborhood Hits	364	Shared Neighborhood Hits	182
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

L1CAM_MOUSE
NC score	0.563692 (rank : 36)	θ value	1.29631e-06 (rank : 27)
Query Neighborhood Hits	281	Target Neighborhood Hits	457	Shared Neighborhood Hits	202
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CHL1_HUMAN
NC score	0.561932 (rank : 37)	θ value	0.000786445 (rank : 60)
Query Neighborhood Hits	281	Target Neighborhood Hits	413	Shared Neighborhood Hits	199
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

SDK1_HUMAN
NC score	0.561419 (rank : 38)	θ value	8.40245e-06 (rank : 31)
Query Neighborhood Hits	281	Target Neighborhood Hits	511	Shared Neighborhood Hits	201
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

L1CAM_HUMAN
NC score	0.560502 (rank : 39)	θ value	5.44631e-05 (rank : 40)
Query Neighborhood Hits	281	Target Neighborhood Hits	457	Shared Neighborhood Hits	200
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CHL1_MOUSE
NC score	0.559288 (rank : 40)	θ value	0.00134147 (rank : 66)
Query Neighborhood Hits	281	Target Neighborhood Hits	402	Shared Neighborhood Hits	201
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

SDK2_HUMAN
NC score	0.557193 (rank : 41)	θ value	0.000158464 (rank : 48)
Query Neighborhood Hits	281	Target Neighborhood Hits	495	Shared Neighborhood Hits	203
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

NCAM2_HUMAN
NC score	0.555623 (rank : 42)	θ value	0.0563607 (rank : 143)
Query Neighborhood Hits	281	Target Neighborhood Hits	441	Shared Neighborhood Hits	203
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

SDK2_MOUSE
NC score	0.555299 (rank : 43)	θ value	0.00020696 (rank : 49)
Query Neighborhood Hits	281	Target Neighborhood Hits	480	Shared Neighborhood Hits	202
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_MOUSE
NC score	0.554824 (rank : 44)	θ value	0.000786445 (rank : 65)
Query Neighborhood Hits	281	Target Neighborhood Hits	495	Shared Neighborhood Hits	199
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

NCA11_MOUSE
NC score	0.554046 (rank : 45)	θ value	5.44631e-05 (rank : 42)
Query Neighborhood Hits	281	Target Neighborhood Hits	661	Shared Neighborhood Hits	203
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCAM2_MOUSE
NC score	0.552704 (rank : 46)	θ value	0.0736092 (rank : 147)
Query Neighborhood Hits	281	Target Neighborhood Hits	472	Shared Neighborhood Hits	203
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

CDON_HUMAN
NC score	0.551610 (rank : 47)	θ value	3.0926 (rank : 229)
Query Neighborhood Hits	281	Target Neighborhood Hits	412	Shared Neighborhood Hits	200
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

NRCAM_MOUSE
NC score	0.550991 (rank : 48)	θ value	0.000461057 (rank : 56)
Query Neighborhood Hits	281	Target Neighborhood Hits	432	Shared Neighborhood Hits	198
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

CNTN4_HUMAN
NC score	0.545667 (rank : 49)	θ value	0.0961366 (rank : 149)
Query Neighborhood Hits	281	Target Neighborhood Hits	449	Shared Neighborhood Hits	202
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN4_MOUSE
NC score	0.544526 (rank : 50)	θ value	0.163984 (rank : 163)
Query Neighborhood Hits	281	Target Neighborhood Hits	445	Shared Neighborhood Hits	202
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

NRCAM_HUMAN
NC score	0.543949 (rank : 51)	θ value	0.00134147 (rank : 71)
Query Neighborhood Hits	281	Target Neighborhood Hits	439	Shared Neighborhood Hits	199
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

CNTN5_HUMAN
NC score	0.543295 (rank : 52)	θ value	0.00298849 (rank : 83)
Query Neighborhood Hits	281	Target Neighborhood Hits	446	Shared Neighborhood Hits	202
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

CNTN2_HUMAN
NC score	0.541890 (rank : 53)	θ value	0.00869519 (rank : 112)
Query Neighborhood Hits	281	Target Neighborhood Hits	440	Shared Neighborhood Hits	203
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
NC score	0.541682 (rank : 54)	θ value	0.00665767 (rank : 104)
Query Neighborhood Hits	281	Target Neighborhood Hits	450	Shared Neighborhood Hits	205
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN5_MOUSE
NC score	0.541348 (rank : 55)	θ value	0.00228821 (rank : 75)
Query Neighborhood Hits	281	Target Neighborhood Hits	434	Shared Neighborhood Hits	203
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CNTN3_HUMAN
NC score	0.538884 (rank : 56)	θ value	0.00390308 (rank : 90)
Query Neighborhood Hits	281	Target Neighborhood Hits	455	Shared Neighborhood Hits	204
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN6_HUMAN
NC score	0.538827 (rank : 57)	θ value	0.00390308 (rank : 91)
Query Neighborhood Hits	281	Target Neighborhood Hits	422	Shared Neighborhood Hits	202
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

FSTL4_MOUSE
NC score	0.538716 (rank : 58)	θ value	0.0252991 (rank : 131)
Query Neighborhood Hits	281	Target Neighborhood Hits	333	Shared Neighborhood Hits	224
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

CNTN1_MOUSE
NC score	0.538276 (rank : 59)	θ value	0.813845 (rank : 198)
Query Neighborhood Hits	281	Target Neighborhood Hits	422	Shared Neighborhood Hits	199
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

FSTL4_HUMAN
NC score	0.537548 (rank : 60)	θ value	0.00509761 (rank : 98)
Query Neighborhood Hits	281	Target Neighborhood Hits	344	Shared Neighborhood Hits	223
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

CNTN6_MOUSE
NC score	0.536518 (rank : 61)	θ value	0.0961366 (rank : 150)
Query Neighborhood Hits	281	Target Neighborhood Hits	429	Shared Neighborhood Hits	200
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

CNTN1_HUMAN
NC score	0.536411 (rank : 62)	θ value	1.06291 (rank : 200)
Query Neighborhood Hits	281	Target Neighborhood Hits	431	Shared Neighborhood Hits	199
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CNTN3_MOUSE
NC score	0.531136 (rank : 63)	θ value	0.0252991 (rank : 129)
Query Neighborhood Hits	281	Target Neighborhood Hits	447	Shared Neighborhood Hits	201
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

FSTL5_HUMAN
NC score	0.529857 (rank : 64)	θ value	0.163984 (rank : 164)
Query Neighborhood Hits	281	Target Neighborhood Hits	347	Shared Neighborhood Hits	220
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

MYPC2_HUMAN
NC score	0.526741 (rank : 65)	θ value	0.00035302 (rank : 53)
Query Neighborhood Hits	281	Target Neighborhood Hits	316	Shared Neighborhood Hits	184
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

FSTL5_MOUSE
NC score	0.525174 (rank : 66)	θ value	0.0961366 (rank : 151)
Query Neighborhood Hits	281	Target Neighborhood Hits	355	Shared Neighborhood Hits	217
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

MYPC2_MOUSE
NC score	0.522972 (rank : 67)	θ value	0.000602161 (rank : 59)
Query Neighborhood Hits	281	Target Neighborhood Hits	297	Shared Neighborhood Hits	183
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

MYPC1_HUMAN
NC score	0.520541 (rank : 68)	θ value	0.00665767 (rank : 109)
Query Neighborhood Hits	281	Target Neighborhood Hits	303	Shared Neighborhood Hits	185
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

OPCM_HUMAN
NC score	0.519992 (rank : 69)	θ value	0.00134147 (rank : 72)
Query Neighborhood Hits	281	Target Neighborhood Hits	332	Shared Neighborhood Hits	199
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

LSAMP_HUMAN
NC score	0.506301 (rank : 70)	θ value	0.62314 (rank : 195)
Query Neighborhood Hits	281	Target Neighborhood Hits	347	Shared Neighborhood Hits	198
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_MOUSE
NC score	0.506023 (rank : 71)	θ value	0.47712 (rank : 189)
Query Neighborhood Hits	281	Target Neighborhood Hits	344	Shared Neighborhood Hits	198
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

RAGE_HUMAN
NC score	0.501999 (rank : 72)	θ value	0.00134147 (rank : 73)
Query Neighborhood Hits	281	Target Neighborhood Hits	269	Shared Neighborhood Hits	183
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

MYPC3_MOUSE
NC score	0.500821 (rank : 73)	θ value	0.000786445 (rank : 62)
Query Neighborhood Hits	281	Target Neighborhood Hits	310	Shared Neighborhood Hits	175
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

NPHN_HUMAN
NC score	0.500572 (rank : 74)	θ value	0.00390308 (rank : 95)
Query Neighborhood Hits	281	Target Neighborhood Hits	362	Shared Neighborhood Hits	189
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

MYPC3_HUMAN
NC score	0.496083 (rank : 75)	θ value	0.00509761 (rank : 101)
Query Neighborhood Hits	281	Target Neighborhood Hits	318	Shared Neighborhood Hits	177
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

NTRI_MOUSE
NC score	0.495255 (rank : 76)	θ value	0.163984 (rank : 167)
Query Neighborhood Hits	281	Target Neighborhood Hits	342	Shared Neighborhood Hits	201
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

MAG_MOUSE
NC score	0.493230 (rank : 77)	θ value	0.0148317 (rank : 121)
Query Neighborhood Hits	281	Target Neighborhood Hits	271	Shared Neighborhood Hits	188
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MYOM1_MOUSE
NC score	0.493033 (rank : 78)	θ value	0.0193708 (rank : 125)
Query Neighborhood Hits	281	Target Neighborhood Hits	415	Shared Neighborhood Hits	178
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

NTRI_HUMAN
NC score	0.491009 (rank : 79)	θ value	0.279714 (rank : 181)
Query Neighborhood Hits	281	Target Neighborhood Hits	344	Shared Neighborhood Hits	200
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

MYBPH_MOUSE
NC score	0.490196 (rank : 80)	θ value	0.00228821 (rank : 80)
Query Neighborhood Hits	281	Target Neighborhood Hits	290	Shared Neighborhood Hits	177
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MAMC1_HUMAN
NC score	0.489113 (rank : 81)	θ value	3.0926 (rank : 233)
Query Neighborhood Hits	281	Target Neighborhood Hits	357	Shared Neighborhood Hits	200
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAG_HUMAN
NC score	0.488843 (rank : 82)	θ value	0.0961366 (rank : 155)
Query Neighborhood Hits	281	Target Neighborhood Hits	278	Shared Neighborhood Hits	189
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAMC1_MOUSE
NC score	0.487800 (rank : 83)	θ value	3.0926 (rank : 234)
Query Neighborhood Hits	281	Target Neighborhood Hits	357	Shared Neighborhood Hits	200
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MDGA1_HUMAN
NC score	0.487524 (rank : 84)	θ value	0.0961366 (rank : 156)
Query Neighborhood Hits	281	Target Neighborhood Hits	358	Shared Neighborhood Hits	198
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

NEGR1_HUMAN
NC score	0.482014 (rank : 85)	θ value	3.0926 (rank : 236)
Query Neighborhood Hits	281	Target Neighborhood Hits	346	Shared Neighborhood Hits	197
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

KIRR2_HUMAN
NC score	0.479934 (rank : 86)	θ value	0.0961366 (rank : 152)
Query Neighborhood Hits	281	Target Neighborhood Hits	321	Shared Neighborhood Hits	177
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

MYOM2_HUMAN
NC score	0.479824 (rank : 87)	θ value	1.38821 (rank : 211)
Query Neighborhood Hits	281	Target Neighborhood Hits	341	Shared Neighborhood Hits	173
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

NEGR1_MOUSE
NC score	0.478936 (rank : 88)	θ value	4.03905 (rank : 243)
Query Neighborhood Hits	281	Target Neighborhood Hits	349	Shared Neighborhood Hits	197
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

MYBPH_HUMAN
NC score	0.477186 (rank : 89)	θ value	0.0563607 (rank : 142)
Query Neighborhood Hits	281	Target Neighborhood Hits	256	Shared Neighborhood Hits	176
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

NPTN_MOUSE
NC score	0.474349 (rank : 90)	θ value	0.47712 (rank : 190)
Query Neighborhood Hits	281	Target Neighborhood Hits	216	Shared Neighborhood Hits	166
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

KIRR2_MOUSE
NC score	0.472704 (rank : 91)	θ value	0.0113563 (rank : 117)
Query Neighborhood Hits	281	Target Neighborhood Hits	326	Shared Neighborhood Hits	177
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

MYOM1_HUMAN
NC score	0.471957 (rank : 92)	θ value	0.279714 (rank : 180)
Query Neighborhood Hits	281	Target Neighborhood Hits	405	Shared Neighborhood Hits	177
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

NPTN_HUMAN
NC score	0.467232 (rank : 93)	θ value	1.38821 (rank : 212)
Query Neighborhood Hits	281	Target Neighborhood Hits	212	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

SN_MOUSE
NC score	0.464210 (rank : 94)	θ value	0.00665767 (rank : 111)
Query Neighborhood Hits	281	Target Neighborhood Hits	416	Shared Neighborhood Hits	197
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

NPHN_MOUSE
NC score	0.463729 (rank : 95)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	281	Target Neighborhood Hits	370	Shared Neighborhood Hits	184
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

SN_HUMAN
NC score	0.463256 (rank : 96)	θ value	0.00390308 (rank : 96)
Query Neighborhood Hits	281	Target Neighborhood Hits	434	Shared Neighborhood Hits	196
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

RAGE_MOUSE
NC score	0.459790 (rank : 97)	θ value	0.279714 (rank : 182)
Query Neighborhood Hits	281	Target Neighborhood Hits	295	Shared Neighborhood Hits	169
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

VCAM1_MOUSE
NC score	0.458809 (rank : 98)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	281	Target Neighborhood Hits	320	Shared Neighborhood Hits	188
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

TMIGD_HUMAN
NC score	0.457043 (rank : 99)	θ value	3.0926 (rank : 237)
Query Neighborhood Hits	281	Target Neighborhood Hits	240	Shared Neighborhood Hits	165
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TMIGD_MOUSE
NC score	0.456198 (rank : 100)	θ value	2.36792 (rank : 227)
Query Neighborhood Hits	281	Target Neighborhood Hits	234	Shared Neighborhood Hits	171
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

VCAM1_HUMAN
NC score	0.456002 (rank : 101)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	281	Target Neighborhood Hits	352	Shared Neighborhood Hits	189
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

HTRA1_MOUSE
NC score	0.449320 (rank : 102)	θ value	1.92812e-18 (rank : 5)
Query Neighborhood Hits	281	Target Neighborhood Hits	140	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

KIRR3_MOUSE
NC score	0.448255 (rank : 103)	θ value	0.00665767 (rank : 107)
Query Neighborhood Hits	281	Target Neighborhood Hits	292	Shared Neighborhood Hits	170
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

KIRR3_HUMAN
NC score	0.447509 (rank : 104)	θ value	0.0193708 (rank : 123)
Query Neighborhood Hits	281	Target Neighborhood Hits	302	Shared Neighborhood Hits	172
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

LU_HUMAN
NC score	0.446823 (rank : 105)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	281	Target Neighborhood Hits	283	Shared Neighborhood Hits	179
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

PGBM_HUMAN
NC score	0.440863 (rank : 106)	θ value	1.43324e-05 (rank : 34)
Query Neighborhood Hits	281	Target Neighborhood Hits	1113	Shared Neighborhood Hits	225
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

HTRA1_HUMAN
NC score	0.438312 (rank : 107)	θ value	6.20254e-17 (rank : 6)
Query Neighborhood Hits	281	Target Neighborhood Hits	155	Shared Neighborhood Hits	55
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

LRIG1_HUMAN
NC score	0.431251 (rank : 108)	θ value	0.00228821 (rank : 79)
Query Neighborhood Hits	281	Target Neighborhood Hits	654	Shared Neighborhood Hits	203
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

MALT1_HUMAN
NC score	0.431044 (rank : 109)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	281	Target Neighborhood Hits	236	Shared Neighborhood Hits	155
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

MFA3L_HUMAN
NC score	0.430842 (rank : 110)	θ value	0.0113563 (rank : 119)
Query Neighborhood Hits	281	Target Neighborhood Hits	230	Shared Neighborhood Hits	174
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

HMCN1_HUMAN
NC score	0.429264 (rank : 111)	θ value	2.44474e-05 (rank : 38)
Query Neighborhood Hits	281	Target Neighborhood Hits	983	Shared Neighborhood Hits	224
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

PGBM_MOUSE
NC score	0.429062 (rank : 112)	θ value	0.000121331 (rank : 46)
Query Neighborhood Hits	281	Target Neighborhood Hits	1073	Shared Neighborhood Hits	227
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ICAM5_MOUSE
NC score	0.427133 (rank : 113)	θ value	2.36792 (rank : 226)
Query Neighborhood Hits	281	Target Neighborhood Hits	308	Shared Neighborhood Hits	183
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

LRIG2_HUMAN
NC score	0.426941 (rank : 114)	θ value	0.0148317 (rank : 120)
Query Neighborhood Hits	281	Target Neighborhood Hits	595	Shared Neighborhood Hits	202
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG2_MOUSE
NC score	0.426742 (rank : 115)	θ value	0.0431538 (rank : 140)
Query Neighborhood Hits	281	Target Neighborhood Hits	586	Shared Neighborhood Hits	203
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG1_MOUSE
NC score	0.426272 (rank : 116)	θ value	0.000602161 (rank : 58)
Query Neighborhood Hits	281	Target Neighborhood Hits	627	Shared Neighborhood Hits	202
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

VSIG2_HUMAN
NC score	0.424405 (rank : 117)	θ value	0.00509761 (rank : 102)
Query Neighborhood Hits	281	Target Neighborhood Hits	321	Shared Neighborhood Hits	180
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

PTPRD_MOUSE
NC score	0.424378 (rank : 118)	θ value	4.1701e-05 (rank : 39)
Query Neighborhood Hits	281	Target Neighborhood Hits	491	Shared Neighborhood Hits	194
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRS_HUMAN
NC score	0.423234 (rank : 119)	θ value	9.92553e-07 (rank : 26)
Query Neighborhood Hits	281	Target Neighborhood Hits	472	Shared Neighborhood Hits	193
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRF_HUMAN
NC score	0.422641 (rank : 120)	θ value	1.87187e-05 (rank : 36)
Query Neighborhood Hits	281	Target Neighborhood Hits	489	Shared Neighborhood Hits	197
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_HUMAN
NC score	0.416867 (rank : 121)	θ value	7.1131e-05 (rank : 45)
Query Neighborhood Hits	281	Target Neighborhood Hits	485	Shared Neighborhood Hits	190
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

KIRR1_HUMAN
NC score	0.416549 (rank : 122)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	281	Target Neighborhood Hits	401	Shared Neighborhood Hits	171
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

CI094_HUMAN
NC score	0.416488 (rank : 123)	θ value	1.38821 (rank : 207)
Query Neighborhood Hits	281	Target Neighborhood Hits	310	Shared Neighborhood Hits	189
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

JAM3_MOUSE
NC score	0.415377 (rank : 124)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	281	Target Neighborhood Hits	286	Shared Neighborhood Hits	176
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

ICAM5_HUMAN
NC score	0.413936 (rank : 125)	θ value	6.88961 (rank : 262)
Query Neighborhood Hits	281	Target Neighborhood Hits	276	Shared Neighborhood Hits	182
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

JAM3_HUMAN
NC score	0.412731 (rank : 126)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	281	Target Neighborhood Hits	271	Shared Neighborhood Hits	178
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

LRIG3_MOUSE
NC score	0.412634 (rank : 127)	θ value	0.00298849 (rank : 87)
Query Neighborhood Hits	281	Target Neighborhood Hits	611	Shared Neighborhood Hits	201
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

KIRR1_MOUSE
NC score	0.411984 (rank : 128)	θ value	4.03905 (rank : 242)
Query Neighborhood Hits	281	Target Neighborhood Hits	403	Shared Neighborhood Hits	168
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

JAM2_HUMAN
NC score	0.411234 (rank : 129)	θ value	1.81305 (rank : 218)
Query Neighborhood Hits	281	Target Neighborhood Hits	304	Shared Neighborhood Hits	189
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM1_HUMAN
NC score	0.410786 (rank : 130)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	281	Target Neighborhood Hits	294	Shared Neighborhood Hits	177
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

CD22_MOUSE
NC score	0.410706 (rank : 131)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	281	Target Neighborhood Hits	331	Shared Neighborhood Hits	170
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

VSIG2_MOUSE
NC score	0.409003 (rank : 132)	θ value	0.365318 (rank : 186)
Query Neighborhood Hits	281	Target Neighborhood Hits	316	Shared Neighborhood Hits	178
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

CD22_HUMAN
NC score	0.408544 (rank : 133)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	281	Target Neighborhood Hits	365	Shared Neighborhood Hits	176
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

MUC18_HUMAN
NC score	0.408368 (rank : 134)	θ value	5.27518 (rank : 253)
Query Neighborhood Hits	281	Target Neighborhood Hits	275	Shared Neighborhood Hits	160
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

LRIG3_HUMAN
NC score	0.406567 (rank : 135)	θ value	0.0330416 (rank : 137)
Query Neighborhood Hits	281	Target Neighborhood Hits	601	Shared Neighborhood Hits	200
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

MUC18_MOUSE
NC score	0.402321 (rank : 136)	θ value	3.0926 (rank : 235)
Query Neighborhood Hits	281	Target Neighborhood Hits	292	Shared Neighborhood Hits	164
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

HTRA3_MOUSE
NC score	0.400929 (rank : 137)	θ value	1.2105e-12 (rank : 8)
Query Neighborhood Hits	281	Target Neighborhood Hits	156	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HTRA3_HUMAN
NC score	0.399577 (rank : 138)	θ value	4.16044e-13 (rank : 7)
Query Neighborhood Hits	281	Target Neighborhood Hits	152	Shared Neighborhood Hits	52
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

SIG11_HUMAN
NC score	0.398033 (rank : 139)	θ value	0.21417 (rank : 176)
Query Neighborhood Hits	281	Target Neighborhood Hits	273	Shared Neighborhood Hits	180
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

NRG2_HUMAN
NC score	0.389173 (rank : 140)	θ value	0.47712 (rank : 191)
Query Neighborhood Hits	281	Target Neighborhood Hits	419	Shared Neighborhood Hits	180
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

JAM2_MOUSE
NC score	0.388108 (rank : 141)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	281	Target Neighborhood Hits	292	Shared Neighborhood Hits	180
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

NRG2_MOUSE
NC score	0.387039 (rank : 142)	θ value	0.21417 (rank : 174)
Query Neighborhood Hits	281	Target Neighborhood Hits	392	Shared Neighborhood Hits	186
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

JAM1_MOUSE
NC score	0.385231 (rank : 143)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	281	Target Neighborhood Hits	287	Shared Neighborhood Hits	174
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

MFA3L_MOUSE
NC score	0.379249 (rank : 144)	θ value	0.0252991 (rank : 132)
Query Neighborhood Hits	281	Target Neighborhood Hits	214	Shared Neighborhood Hits	160
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

IGS4B_MOUSE
NC score	0.375763 (rank : 145)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	281	Target Neighborhood Hits	328	Shared Neighborhood Hits	175
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

BASI_HUMAN
NC score	0.374180 (rank : 146)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	281	Target Neighborhood Hits	211	Shared Neighborhood Hits	157
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

SIG10_HUMAN
NC score	0.372021 (rank : 147)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	281	Target Neighborhood Hits	363	Shared Neighborhood Hits	171
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

BASI_MOUSE
NC score	0.368458 (rank : 148)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	281	Target Neighborhood Hits	238	Shared Neighborhood Hits	155
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

IGS4B_HUMAN
NC score	0.367218 (rank : 149)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	281	Target Neighborhood Hits	305	Shared Neighborhood Hits	169
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

CEAM5_HUMAN
NC score	0.360470 (rank : 150)	θ value	2.36792 (rank : 222)
Query Neighborhood Hits	281	Target Neighborhood Hits	343	Shared Neighborhood Hits	180
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

CEAM1_MOUSE
NC score	0.356693 (rank : 151)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	281	Target Neighborhood Hits	326	Shared Neighborhood Hits	177
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

TITIN_HUMAN
NC score	0.351633 (rank : 152)	θ value	1.09739e-05 (rank : 32)
Query Neighborhood Hits	281	Target Neighborhood Hits	2923	Shared Neighborhood Hits	209
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

FCRL5_HUMAN
NC score	0.349264 (rank : 153)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	281	Target Neighborhood Hits	267	Shared Neighborhood Hits	149
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

ATL3_HUMAN
NC score	0.344948 (rank : 154)	θ value	0.00175202 (rank : 74)
Query Neighborhood Hits	281	Target Neighborhood Hits	414	Shared Neighborhood Hits	204
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

CEA20_HUMAN
NC score	0.338577 (rank : 155)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	281	Target Neighborhood Hits	251	Shared Neighborhood Hits	149
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

HTRA4_HUMAN
NC score	0.336980 (rank : 156)	θ value	0.00298849 (rank : 84)
Query Neighborhood Hits	281	Target Neighborhood Hits	119	Shared Neighborhood Hits	39
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

LRFN4_HUMAN
NC score	0.326845 (rank : 157)	θ value	0.00665767 (rank : 108)
Query Neighborhood Hits	281	Target Neighborhood Hits	462	Shared Neighborhood Hits	175
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN4_MOUSE
NC score	0.325152 (rank : 158)	θ value	0.00298849 (rank : 86)
Query Neighborhood Hits	281	Target Neighborhood Hits	442	Shared Neighborhood Hits	174
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

FNDC3_MOUSE
NC score	0.322505 (rank : 159)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	281	Target Neighborhood Hits	207	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_HUMAN
NC score	0.322279 (rank : 160)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	281	Target Neighborhood Hits	196	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

NRG1_HUMAN
NC score	0.321658 (rank : 161)	θ value	0.0330416 (rank : 138)
Query Neighborhood Hits	281	Target Neighborhood Hits	285	Shared Neighborhood Hits	138
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

FCRL2_HUMAN
NC score	0.320600 (rank : 162)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	281	Target Neighborhood Hits	251	Shared Neighborhood Hits	141
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

CEAM1_HUMAN
NC score	0.316875 (rank : 163)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	281	Target Neighborhood Hits	348	Shared Neighborhood Hits	170
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

LRFN2_HUMAN
NC score	0.311948 (rank : 164)	θ value	0.0961366 (rank : 154)
Query Neighborhood Hits	281	Target Neighborhood Hits	450	Shared Neighborhood Hits	172
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

PTK7_HUMAN
NC score	0.310121 (rank : 165)	θ value	0.0252991 (rank : 133)
Query Neighborhood Hits	281	Target Neighborhood Hits	1103	Shared Neighborhood Hits	202
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

VSIG4_HUMAN
NC score	0.308546 (rank : 166)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	281	Target Neighborhood Hits	236	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

LRFN3_MOUSE
NC score	0.305695 (rank : 167)	θ value	0.0330416 (rank : 136)
Query Neighborhood Hits	281	Target Neighborhood Hits	455	Shared Neighborhood Hits	179
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

OBSCN_HUMAN
NC score	0.305501 (rank : 168)	θ value	8.11959e-09 (rank : 14)
Query Neighborhood Hits	281	Target Neighborhood Hits	1931	Shared Neighborhood Hits	206
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

CD166_MOUSE
NC score	0.303918 (rank : 169)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	281	Target Neighborhood Hits	252	Shared Neighborhood Hits	142
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

GPA33_MOUSE
NC score	0.302528 (rank : 170)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	281	Target Neighborhood Hits	294	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

LRFN2_MOUSE
NC score	0.301043 (rank : 171)	θ value	0.0736092 (rank : 146)
Query Neighborhood Hits	281	Target Neighborhood Hits	450	Shared Neighborhood Hits	172
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

CILP2_HUMAN
NC score	0.300115 (rank : 172)	θ value	0.00665767 (rank : 103)
Query Neighborhood Hits	281	Target Neighborhood Hits	307	Shared Neighborhood Hits	153
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

SIGL5_MOUSE
NC score	0.293059 (rank : 173)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	281	Target Neighborhood Hits	271	Shared Neighborhood Hits	167
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

LRFN3_HUMAN
NC score	0.291758 (rank : 174)	θ value	0.163984 (rank : 166)
Query Neighborhood Hits	281	Target Neighborhood Hits	444	Shared Neighborhood Hits	171
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

MUSK_MOUSE
NC score	0.286123 (rank : 175)	θ value	0.00509761 (rank : 100)
Query Neighborhood Hits	281	Target Neighborhood Hits	1057	Shared Neighborhood Hits	200
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

GPA33_HUMAN
NC score	0.284733 (rank : 176)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	281	Target Neighborhood Hits	273	Shared Neighborhood Hits	140
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

MUSK_HUMAN
NC score	0.283618 (rank : 177)	θ value	0.00298849 (rank : 88)
Query Neighborhood Hits	281	Target Neighborhood Hits	1074	Shared Neighborhood Hits	200
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

SPEG_HUMAN
NC score	0.282914 (rank : 178)	θ value	0.00035302 (rank : 54)
Query Neighborhood Hits	281	Target Neighborhood Hits	1762	Shared Neighborhood Hits	202
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_MOUSE
NC score	0.282842 (rank : 179)	θ value	0.000270298 (rank : 51)
Query Neighborhood Hits	281	Target Neighborhood Hits	1959	Shared Neighborhood Hits	201
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CD166_HUMAN
NC score	0.281760 (rank : 180)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	281	Target Neighborhood Hits	247	Shared Neighborhood Hits	135
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

MYLK_MOUSE
NC score	0.281247 (rank : 181)	θ value	2.61198e-07 (rank : 20)
Query Neighborhood Hits	281	Target Neighborhood Hits	1489	Shared Neighborhood Hits	202
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYLK_HUMAN
NC score	0.280248 (rank : 182)	θ value	2.88788e-06 (rank : 29)
Query Neighborhood Hits	281	Target Neighborhood Hits	1328	Shared Neighborhood Hits	206
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

LRC21_MOUSE
NC score	0.279504 (rank : 183)	θ value	1.06291 (rank : 203)
Query Neighborhood Hits	281	Target Neighborhood Hits	462	Shared Neighborhood Hits	176
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC21_HUMAN
NC score	0.279236 (rank : 184)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	281	Target Neighborhood Hits	456	Shared Neighborhood Hits	177
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRFN5_MOUSE
NC score	0.275982 (rank : 185)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	281	Target Neighborhood Hits	472	Shared Neighborhood Hits	180
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRFN5_HUMAN
NC score	0.270540 (rank : 186)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	281	Target Neighborhood Hits	464	Shared Neighborhood Hits	177
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

CEAM6_HUMAN
NC score	0.264517 (rank : 187)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	281	Target Neighborhood Hits	308	Shared Neighborhood Hits	170
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

ESAM_HUMAN
NC score	0.264490 (rank : 188)	θ value	2.36792 (rank : 224)
Query Neighborhood Hits	281	Target Neighborhood Hits	251	Shared Neighborhood Hits	130
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

SIGL8_HUMAN
NC score	0.257549 (rank : 189)	θ value	0.62314 (rank : 196)
Query Neighborhood Hits	281	Target Neighborhood Hits	252	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

VGFR1_HUMAN
NC score	0.256161 (rank : 190)	θ value	0.163984 (rank : 168)
Query Neighborhood Hits	281	Target Neighborhood Hits	1109	Shared Neighborhood Hits	201
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

CD276_HUMAN
NC score	0.255381 (rank : 191)	θ value	0.125558 (rank : 158)
Query Neighborhood Hits	281	Target Neighborhood Hits	261	Shared Neighborhood Hits	117
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

SIGL5_HUMAN
NC score	0.254358 (rank : 192)	θ value	4.03905 (rank : 246)
Query Neighborhood Hits	281	Target Neighborhood Hits	246	Shared Neighborhood Hits	143
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

VGFR1_MOUSE
NC score	0.253269 (rank : 193)	θ value	0.0193708 (rank : 128)
Query Neighborhood Hits	281	Target Neighborhood Hits	1118	Shared Neighborhood Hits	202
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

IBP3_HUMAN
NC score	0.251166 (rank : 194)	θ value	0.000786445 (rank : 61)
Query Neighborhood Hits	281	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

LRC24_HUMAN
NC score	0.249186 (rank : 195)	θ value	0.0113563 (rank : 118)
Query Neighborhood Hits	281	Target Neighborhood Hits	404	Shared Neighborhood Hits	162
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRRN1_HUMAN
NC score	0.247252 (rank : 196)	θ value	0.62314 (rank : 194)
Query Neighborhood Hits	281	Target Neighborhood Hits	518	Shared Neighborhood Hits	188
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LRRN3_HUMAN
NC score	0.245801 (rank : 197)	θ value	3.0926 (rank : 232)
Query Neighborhood Hits	281	Target Neighborhood Hits	461	Shared Neighborhood Hits	170
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

SIG12_HUMAN
NC score	0.244555 (rank : 198)	θ value	1.38821 (rank : 214)
Query Neighborhood Hits	281	Target Neighborhood Hits	245	Shared Neighborhood Hits	166
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

IBP2_MOUSE
NC score	0.241781 (rank : 199)	θ value	0.000461057 (rank : 55)
Query Neighborhood Hits	281	Target Neighborhood Hits	65	Shared Neighborhood Hits	41
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

ESAM_MOUSE
NC score	0.240021 (rank : 200)	θ value	2.36792 (rank : 225)
Query Neighborhood Hits	281	Target Neighborhood Hits	222	Shared Neighborhood Hits	131
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

IBP2_HUMAN
NC score	0.237097 (rank : 201)	θ value	0.00298849 (rank : 85)
Query Neighborhood Hits	281	Target Neighborhood Hits	61	Shared Neighborhood Hits	40
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

LRRN1_MOUSE
NC score	0.236771 (rank : 202)	θ value	1.38821 (rank : 210)
Query Neighborhood Hits	281	Target Neighborhood Hits	508	Shared Neighborhood Hits	185
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

IBP5_MOUSE
NC score	0.236225 (rank : 203)	θ value	0.00390308 (rank : 93)
Query Neighborhood Hits	281	Target Neighborhood Hits	68	Shared Neighborhood Hits	40
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IL1R2_HUMAN
NC score	0.235561 (rank : 204)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	281	Target Neighborhood Hits	153	Shared Neighborhood Hits	102
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

IBP5_HUMAN
NC score	0.235335 (rank : 205)	θ value	0.00509761 (rank : 99)
Query Neighborhood Hits	281	Target Neighborhood Hits	68	Shared Neighborhood Hits	40
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

LRRN5_HUMAN
NC score	0.234055 (rank : 206)	θ value	1.81305 (rank : 219)
Query Neighborhood Hits	281	Target Neighborhood Hits	493	Shared Neighborhood Hits	181
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

VGFR2_HUMAN
NC score	0.232644 (rank : 207)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	281	Target Neighborhood Hits	1103	Shared Neighborhood Hits	195
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

VGFR2_MOUSE
NC score	0.232073 (rank : 208)	θ value	5.27518 (rank : 260)
Query Neighborhood Hits	281	Target Neighborhood Hits	1089	Shared Neighborhood Hits	197
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

CEAM8_HUMAN
NC score	0.231817 (rank : 209)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	281	Target Neighborhood Hits	264	Shared Neighborhood Hits	163
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

FGFR4_MOUSE
NC score	0.229602 (rank : 210)	θ value	0.000270298 (rank : 50)
Query Neighborhood Hits	281	Target Neighborhood Hits	1026	Shared Neighborhood Hits	196
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

FINC_MOUSE
NC score	0.229569 (rank : 211)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	281	Target Neighborhood Hits	309	Shared Neighborhood Hits	85
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

LRRN3_MOUSE
NC score	0.229331 (rank : 212)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	281	Target Neighborhood Hits	455	Shared Neighborhood Hits	167
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

SIGL6_HUMAN
NC score	0.227660 (rank : 213)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	281	Target Neighborhood Hits	233	Shared Neighborhood Hits	148
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

LRC24_MOUSE
NC score	0.226912 (rank : 214)	θ value	0.0961366 (rank : 153)
Query Neighborhood Hits	281	Target Neighborhood Hits	387	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

FINC_HUMAN
NC score	0.226548 (rank : 215)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	281	Target Neighborhood Hits	302	Shared Neighborhood Hits	89
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

CXAR_HUMAN
NC score	0.225531 (rank : 216)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	281	Target Neighborhood Hits	245	Shared Neighborhood Hits	119
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

IBP1_MOUSE
NC score	0.224861 (rank : 217)	θ value	0.125558 (rank : 160)
Query Neighborhood Hits	281	Target Neighborhood Hits	97	Shared Neighborhood Hits	40
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

FGFR4_HUMAN
NC score	0.224822 (rank : 218)	θ value	0.00228821 (rank : 77)
Query Neighborhood Hits	281	Target Neighborhood Hits	1037	Shared Neighborhood Hits	197
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

ESM1_MOUSE
NC score	0.224072 (rank : 219)	θ value	1.06291 (rank : 201)
Query Neighborhood Hits	281	Target Neighborhood Hits	107	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FGFR1_HUMAN
NC score	0.223931 (rank : 220)	θ value	0.00134147 (rank : 67)
Query Neighborhood Hits	281	Target Neighborhood Hits	1069	Shared Neighborhood Hits	192
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR1_MOUSE
NC score	0.223921 (rank : 221)	θ value	0.00134147 (rank : 68)
Query Neighborhood Hits	281	Target Neighborhood Hits	1068	Shared Neighborhood Hits	191
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

CXAR_MOUSE
NC score	0.223323 (rank : 222)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	281	Target Neighborhood Hits	250	Shared Neighborhood Hits	119
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

FGFR3_MOUSE
NC score	0.222993 (rank : 223)	θ value	0.000158464 (rank : 47)
Query Neighborhood Hits	281	Target Neighborhood Hits	1059	Shared Neighborhood Hits	193
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

UNC5D_MOUSE
NC score	0.221951 (rank : 224)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	281	Target Neighborhood Hits	268	Shared Neighborhood Hits	148
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

FSTL3_HUMAN
NC score	0.221856 (rank : 225)	θ value	0.0252991 (rank : 130)
Query Neighborhood Hits	281	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

PSG4_HUMAN
NC score	0.221223 (rank : 226)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	281	Target Neighborhood Hits	243	Shared Neighborhood Hits	149
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

PSG3_HUMAN
NC score	0.220148 (rank : 227)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	281	Target Neighborhood Hits	242	Shared Neighborhood Hits	150
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

UNC5D_HUMAN
NC score	0.217600 (rank : 228)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	281	Target Neighborhood Hits	267	Shared Neighborhood Hits	148
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

PSG11_HUMAN
NC score	0.216791 (rank : 229)	θ value	4.03905 (rank : 245)
Query Neighborhood Hits	281	Target Neighborhood Hits	223	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

ISK6_HUMAN
NC score	0.216593 (rank : 230)	θ value	0.00134147 (rank : 69)
Query Neighborhood Hits	281	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

PSG8_HUMAN
NC score	0.216282 (rank : 231)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	281	Target Neighborhood Hits	239	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

CILP1_MOUSE
NC score	0.215413 (rank : 232)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	281	Target Neighborhood Hits	282	Shared Neighborhood Hits	149
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

FGFR3_HUMAN
NC score	0.214620 (rank : 233)	θ value	0.000602161 (rank : 57)
Query Neighborhood Hits	281	Target Neighborhood Hits	1042	Shared Neighborhood Hits	191
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

FGFR2_HUMAN
NC score	0.211394 (rank : 234)	θ value	0.00390308 (rank : 92)
Query Neighborhood Hits	281	Target Neighborhood Hits	1062	Shared Neighborhood Hits	191
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

PSG7_HUMAN
NC score	0.211158 (rank : 235)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	281	Target Neighborhood Hits	239	Shared Neighborhood Hits	152
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

FST_MOUSE
NC score	0.209974 (rank : 236)	θ value	0.00228821 (rank : 78)
Query Neighborhood Hits	281	Target Neighborhood Hits	146	Shared Neighborhood Hits	43
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

IRPL2_HUMAN
NC score	0.209708 (rank : 237)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	281	Target Neighborhood Hits	194	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

NGL1_MOUSE
NC score	0.209235 (rank : 238)	θ value	0.21417 (rank : 173)
Query Neighborhood Hits	281	Target Neighborhood Hits	512	Shared Neighborhood Hits	163
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_HUMAN
NC score	0.208972 (rank : 239)	θ value	0.21417 (rank : 172)
Query Neighborhood Hits	281	Target Neighborhood Hits	511	Shared Neighborhood Hits	163
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

IRPL1_MOUSE
NC score	0.208484 (rank : 240)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	281	Target Neighborhood Hits	186	Shared Neighborhood Hits	123
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

LRC4B_MOUSE
NC score	0.207218 (rank : 241)	θ value	3.0926 (rank : 231)
Query Neighborhood Hits	281	Target Neighborhood Hits	484	Shared Neighborhood Hits	163
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

FST_HUMAN
NC score	0.207137 (rank : 242)	θ value	0.00665767 (rank : 106)
Query Neighborhood Hits	281	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

IRPL2_MOUSE
NC score	0.206779 (rank : 243)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	281	Target Neighborhood Hits	195	Shared Neighborhood Hits	115
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

LRC4B_HUMAN
NC score	0.205384 (rank : 244)	θ value	3.0926 (rank : 230)
Query Neighborhood Hits	281	Target Neighborhood Hits	479	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

DUET_HUMAN
NC score	0.204797 (rank : 245)	θ value	0.00228821 (rank : 76)
Query Neighborhood Hits	281	Target Neighborhood Hits	1220	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

PSG1_HUMAN
NC score	0.204390 (rank : 246)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	281	Target Neighborhood Hits	232	Shared Neighborhood Hits	148
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

FGFR2_MOUSE
NC score	0.203633 (rank : 247)	θ value	0.00509761 (rank : 97)
Query Neighborhood Hits	281	Target Neighborhood Hits	1062	Shared Neighborhood Hits	186
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

FSTL1_HUMAN
NC score	0.203604 (rank : 248)	θ value	0.00665767 (rank : 105)
Query Neighborhood Hits	281	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

IRPL1_HUMAN
NC score	0.203113 (rank : 249)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	281	Target Neighborhood Hits	196	Shared Neighborhood Hits	125
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

PSG2_HUMAN
NC score	0.202756 (rank : 250)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	281	Target Neighborhood Hits	229	Shared Neighborhood Hits	147
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

IBP3_MOUSE
NC score	0.201607 (rank : 251)	θ value	0.163984 (rank : 165)
Query Neighborhood Hits	281	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

FSTL3_MOUSE
NC score	0.201579 (rank : 252)	θ value	0.62314 (rank : 193)
Query Neighborhood Hits	281	Target Neighborhood Hits	152	Shared Neighborhood Hits	44
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

HTRA2_MOUSE
NC score	0.201202 (rank : 253)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	281	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

FSTL1_MOUSE
NC score	0.200787 (rank : 254)	θ value	0.0113563 (rank : 116)
Query Neighborhood Hits	281	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

HTRA2_HUMAN
NC score	0.200632 (rank : 255)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	281	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

IBP1_HUMAN
NC score	0.200294 (rank : 256)	θ value	1.81305 (rank : 216)
Query Neighborhood Hits	281	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

CD276_MOUSE
NC score	0.200153 (rank : 257)	θ value	0.47712 (rank : 187)
Query Neighborhood Hits	281	Target Neighborhood Hits	243	Shared Neighborhood Hits	120
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CILP1_HUMAN
NC score	0.200131 (rank : 258)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	281	Target Neighborhood Hits	266	Shared Neighborhood Hits	140
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

ESM1_HUMAN
NC score	0.199747 (rank : 259)	θ value	0.21417 (rank : 169)
Query Neighborhood Hits	281	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

PSG6_HUMAN
NC score	0.197715 (rank : 260)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	281	Target Neighborhood Hits	231	Shared Neighborhood Hits	140
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

USH2A_HUMAN
NC score	0.197336 (rank : 261)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	281	Target Neighborhood Hits	600	Shared Neighborhood Hits	94
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LRRC4_HUMAN
NC score	0.196816 (rank : 262)	θ value	0.0193708 (rank : 124)
Query Neighborhood Hits	281	Target Neighborhood Hits	444	Shared Neighborhood Hits	153
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

MOX2R_MOUSE
NC score	0.196508 (rank : 263)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	281	Target Neighborhood Hits	110	Shared Neighborhood Hits	79
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

IBP4_HUMAN
NC score	0.195913 (rank : 264)	θ value	0.0431538 (rank : 139)
Query Neighborhood Hits	281	Target Neighborhood Hits	52	Shared Neighborhood Hits	35
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

PVRL3_MOUSE
NC score	0.194965 (rank : 265)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	281	Target Neighborhood Hits	212	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

PSG10_HUMAN
NC score	0.193988 (rank : 266)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	281	Target Neighborhood Hits	227	Shared Neighborhood Hits	139
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

TYRO3_HUMAN
NC score	0.193886 (rank : 267)	θ value	3.0926 (rank : 238)
Query Neighborhood Hits	281	Target Neighborhood Hits	995	Shared Neighborhood Hits	170
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

IL6RB_HUMAN
NC score	0.193432 (rank : 268)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	281	Target Neighborhood Hits	181	Shared Neighborhood Hits	62
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL1R2_MOUSE
NC score	0.193015 (rank : 269)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	281	Target Neighborhood Hits	125	Shared Neighborhood Hits	82
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

TYRO3_MOUSE
NC score	0.191864 (rank : 270)	θ value	1.38821 (rank : 215)
Query Neighborhood Hits	281	Target Neighborhood Hits	1007	Shared Neighborhood Hits	176
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

VGFR3_HUMAN
NC score	0.191821 (rank : 271)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	281	Target Neighborhood Hits	1037	Shared Neighborhood Hits	176
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VGFR3_MOUSE
NC score	0.191729 (rank : 272)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	281	Target Neighborhood Hits	1056	Shared Neighborhood Hits	186
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

IBP4_MOUSE
NC score	0.190027 (rank : 273)	θ value	0.125558 (rank : 161)
Query Neighborhood Hits	281	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

PIGR_MOUSE
NC score	0.189791 (rank : 274)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	281	Target Neighborhood Hits	214	Shared Neighborhood Hits	107
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

PVRL1_HUMAN
NC score	0.188524 (rank : 275)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	281	Target Neighborhood Hits	219	Shared Neighborhood Hits	114
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

ISK6_MOUSE
NC score	0.187807 (rank : 276)	θ value	0.0736092 (rank : 145)
Query Neighborhood Hits	281	Target Neighborhood Hits	37	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

USH2A_MOUSE
NC score	0.187673 (rank : 277)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	281	Target Neighborhood Hits	626	Shared Neighborhood Hits	91
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

PSG9_HUMAN
NC score	0.185420 (rank : 278)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	281	Target Neighborhood Hits	221	Shared Neighborhood Hits	140
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

PVRL3_HUMAN
NC score	0.185416 (rank : 279)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	281	Target Neighborhood Hits	204	Shared Neighborhood Hits	106
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

ITB4_HUMAN
NC score	0.185175 (rank : 280)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	281	Target Neighborhood Hits	458	Shared Neighborhood Hits	84
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ROR2_MOUSE
NC score	0.182141 (rank : 281)	θ value	0.000786445 (rank : 64)
Query Neighborhood Hits	281	Target Neighborhood Hits	1000	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

PDL1_HUMAN
NC score	0.180705 (rank : 282)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	281	Target Neighborhood Hits	195	Shared Neighborhood Hits	108
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PSG5_HUMAN
NC score	0.179233 (rank : 283)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	281	Target Neighborhood Hits	231	Shared Neighborhood Hits	140
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

PECA1_HUMAN
NC score	0.179217 (rank : 284)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	281	Target Neighborhood Hits	178	Shared Neighborhood Hits	103
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

IL6RB_MOUSE
NC score	0.178713 (rank : 285)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	281	Target Neighborhood Hits	168	Shared Neighborhood Hits	64
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

SIG12_MOUSE
NC score	0.178689 (rank : 286)	θ value	0.0252991 (rank : 134)
Query Neighborhood Hits	281	Target Neighborhood Hits	225	Shared Neighborhood Hits	117
SwissProt Accessions	Q91Y57	Gene names	Siglec12, Siglec5, Siglece, Siglecl1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (mSiglec-E) (Myeloid inhibitory siglec) (MIS).

SIGL7_HUMAN
NC score	0.178443 (rank : 287)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	281	Target Neighborhood Hits	180	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y286, Q9NZQ1, Q9UJ86, Q9UJ87, Q9Y502	Gene names	SIGLEC7, AIRM1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 7 precursor (Siglec-7) (QA79 membrane protein) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (p75) (D-siglec) (CDw328 antigen).

EMB_MOUSE
NC score	0.177622 (rank : 288)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	281	Target Neighborhood Hits	83	Shared Neighborhood Hits	67
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

IL1R1_HUMAN
NC score	0.175998 (rank : 289)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	281	Target Neighborhood Hits	140	Shared Neighborhood Hits	99
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

PGFRL_HUMAN
NC score	0.175989 (rank : 290)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	281	Target Neighborhood Hits	115	Shared Neighborhood Hits	92
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

PIGR_HUMAN
NC score	0.175362 (rank : 291)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	281	Target Neighborhood Hits	164	Shared Neighborhood Hits	85
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

SMOC1_MOUSE
NC score	0.174985 (rank : 292)	θ value	0.00665767 (rank : 110)
Query Neighborhood Hits	281	Target Neighborhood Hits	74	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

ROR2_HUMAN
NC score	0.174637 (rank : 293)	θ value	0.00228821 (rank : 81)
Query Neighborhood Hits	281	Target Neighborhood Hits	1014	Shared Neighborhood Hits	179
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

UNC5C_MOUSE
NC score	0.173781 (rank : 294)	θ value	5.27518 (rank : 259)
Query Neighborhood Hits	281	Target Neighborhood Hits	225	Shared Neighborhood Hits	116
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

COCA1_MOUSE
NC score	0.172596 (rank : 295)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	281	Target Neighborhood Hits	467	Shared Neighborhood Hits	82
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

CSF1R_MOUSE
NC score	0.172435 (rank : 296)	θ value	0.47712 (rank : 188)
Query Neighborhood Hits	281	Target Neighborhood Hits	983	Shared Neighborhood Hits	160
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

LRRC4_MOUSE
NC score	0.171008 (rank : 297)	θ value	0.21417 (rank : 171)
Query Neighborhood Hits	281	Target Neighborhood Hits	412	Shared Neighborhood Hits	133
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

CRIM1_HUMAN
NC score	0.170314 (rank : 298)	θ value	2.88788e-06 (rank : 28)
Query Neighborhood Hits	281	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CTGF_HUMAN
NC score	0.170022 (rank : 299)	θ value	0.0113563 (rank : 115)
Query Neighborhood Hits	281	Target Neighborhood Hits	128	Shared Neighborhood Hits	37
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

KALM_HUMAN
NC score	0.169865 (rank : 300)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	281	Target Neighborhood Hits	114	Shared Neighborhood Hits	48
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

UNC5C_HUMAN
NC score	0.169619 (rank : 301)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	281	Target Neighborhood Hits	226	Shared Neighborhood Hits	113
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

LIFR_HUMAN
NC score	0.169027 (rank : 302)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	281	Target Neighborhood Hits	130	Shared Neighborhood Hits	49
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

UNC5A_HUMAN
NC score	0.167454 (rank : 303)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	281	Target Neighborhood Hits	198	Shared Neighborhood Hits	103
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

IGS21_MOUSE
NC score	0.166700 (rank : 304)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	281	Target Neighborhood Hits	118	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

AGRIN_HUMAN
NC score	0.166105 (rank : 305)	θ value	4.45536e-07 (rank : 23)
Query Neighborhood Hits	281	Target Neighborhood Hits	582	Shared Neighborhood Hits	62
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

IGS21_HUMAN
NC score	0.164954 (rank : 306)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	281	Target Neighborhood Hits	123	Shared Neighborhood Hits	86
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

SMOC1_HUMAN
NC score	0.164123 (rank : 307)	θ value	0.0193708 (rank : 126)
Query Neighborhood Hits	281	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

IL1R1_MOUSE
NC score	0.163660 (rank : 308)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	281	Target Neighborhood Hits	142	Shared Neighborhood Hits	99
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

UNC5B_HUMAN
NC score	0.162935 (rank : 309)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	281	Target Neighborhood Hits	225	Shared Neighborhood Hits	114
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

TEFF2_MOUSE
NC score	0.162419 (rank : 310)	θ value	0.365318 (rank : 185)
Query Neighborhood Hits	281	Target Neighborhood Hits	214	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

PVRL1_MOUSE
NC score	0.162252 (rank : 311)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	281	Target Neighborhood Hits	201	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

SMOC2_MOUSE
NC score	0.162070 (rank : 312)	θ value	0.0193708 (rank : 127)
Query Neighborhood Hits	281	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

PDL2_MOUSE
NC score	0.161950 (rank : 313)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	281	Target Neighborhood Hits	116	Shared Neighborhood Hits	84
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

COCA1_HUMAN
NC score	0.161572 (rank : 314)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	281	Target Neighborhood Hits	458	Shared Neighborhood Hits	73
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

LIFR_MOUSE
NC score	0.161466 (rank : 315)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	281	Target Neighborhood Hits	127	Shared Neighborhood Hits	50
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

TEFF2_HUMAN
NC score	0.160689 (rank : 316)	θ value	0.365318 (rank : 184)
Query Neighborhood Hits	281	Target Neighborhood Hits	211	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

NTRK3_HUMAN
NC score	0.159303 (rank : 317)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	281	Target Neighborhood Hits	1115	Shared Neighborhood Hits	176
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

UNC5B_MOUSE
NC score	0.159179 (rank : 318)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	281	Target Neighborhood Hits	226	Shared Neighborhood Hits	118
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

TRIO_HUMAN
NC score	0.159061 (rank : 319)	θ value	4.92598e-06 (rank : 30)
Query Neighborhood Hits	281	Target Neighborhood Hits	1580	Shared Neighborhood Hits	188
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

PVR_HUMAN
NC score	0.158853 (rank : 320)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	281	Target Neighborhood Hits	195	Shared Neighborhood Hits	97
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

TICN2_MOUSE
NC score	0.158111 (rank : 321)	θ value	0.0148317 (rank : 122)
Query Neighborhood Hits	281	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

NTRK2_MOUSE
NC score	0.158044 (rank : 322)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	281	Target Neighborhood Hits	1088	Shared Neighborhood Hits	179
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK2_HUMAN
NC score	0.157917 (rank : 323)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	281	Target Neighborhood Hits	1081	Shared Neighborhood Hits	178
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

PDL1_MOUSE
NC score	0.157330 (rank : 324)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	281	Target Neighborhood Hits	168	Shared Neighborhood Hits	92
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

SMOC2_HUMAN
NC score	0.156176 (rank : 325)	θ value	0.0961366 (rank : 157)
Query Neighborhood Hits	281	Target Neighborhood Hits	88	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

ILRL2_MOUSE
NC score	0.155293 (rank : 326)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	281	Target Neighborhood Hits	158	Shared Neighborhood Hits	111
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

ROR1_HUMAN
NC score	0.154695 (rank : 327)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	281	Target Neighborhood Hits	1018	Shared Neighborhood Hits	178
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
NC score	0.154562 (rank : 328)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	281	Target Neighborhood Hits	1025	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

MERTK_HUMAN
NC score	0.153299 (rank : 329)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	281	Target Neighborhood Hits	988	Shared Neighborhood Hits	147
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

ILRL1_HUMAN
NC score	0.152475 (rank : 330)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	281	Target Neighborhood Hits	167	Shared Neighborhood Hits	99
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

PTPRM_HUMAN
NC score	0.152440 (rank : 331)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	281	Target Neighborhood Hits	244	Shared Neighborhood Hits	83
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

UFO_MOUSE
NC score	0.152363 (rank : 332)	θ value	5.27518 (rank : 258)
Query Neighborhood Hits	281	Target Neighborhood Hits	988	Shared Neighborhood Hits	152
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

TICN2_HUMAN
NC score	0.152048 (rank : 333)	θ value	0.0563607 (rank : 144)
Query Neighborhood Hits	281	Target Neighborhood Hits	68	Shared Neighborhood Hits	41
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

WISP2_HUMAN
NC score	0.150812 (rank : 334)	θ value	2.36792 (rank : 228)
Query Neighborhood Hits	281	Target Neighborhood Hits	126	Shared Neighborhood Hits	36
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

MERTK_MOUSE
NC score	0.150174 (rank : 335)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	281	Target Neighborhood Hits	974	Shared Neighborhood Hits	144
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

PGFRL_MOUSE
NC score	0.149837 (rank : 336)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	281	Target Neighborhood Hits	106	Shared Neighborhood Hits	81
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

I12R2_HUMAN
NC score	0.149758 (rank : 337)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	281	Target Neighborhood Hits	163	Shared Neighborhood Hits	47
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I12R2_MOUSE
NC score	0.149052 (rank : 338)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	281	Target Neighborhood Hits	143	Shared Neighborhood Hits	50
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

UNC5A_MOUSE
NC score	0.149004 (rank : 339)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	281	Target Neighborhood Hits	203	Shared Neighborhood Hits	101
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

PTPRM_MOUSE
NC score	0.148569 (rank : 340)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	281	Target Neighborhood Hits	238	Shared Neighborhood Hits	83
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

UFO_HUMAN
NC score	0.148137 (rank : 341)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	281	Target Neighborhood Hits	981	Shared Neighborhood Hits	145
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

CYR61_MOUSE
NC score	0.147867 (rank : 342)	θ value	0.279714 (rank : 178)
Query Neighborhood Hits	281	Target Neighborhood Hits	156	Shared Neighborhood Hits	38
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

CYR61_HUMAN
NC score	0.147695 (rank : 343)	θ value	0.279714 (rank : 177)
Query Neighborhood Hits	281	Target Neighborhood Hits	159	Shared Neighborhood Hits	37
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

NOV_HUMAN
NC score	0.146224 (rank : 344)	θ value	0.0431538 (rank : 141)
Query Neighborhood Hits	281	Target Neighborhood Hits	128	Shared Neighborhood Hits	37
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

COEA1_MOUSE
NC score	0.146030 (rank : 345)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	281	Target Neighborhood Hits	402	Shared Neighborhood Hits	61
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

PECA1_MOUSE
NC score	0.145956 (rank : 346)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	281	Target Neighborhood Hits	126	Shared Neighborhood Hits	72
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

PGFRA_HUMAN
NC score	0.145785 (rank : 347)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	281	Target Neighborhood Hits	980	Shared Neighborhood Hits	152
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

WISP2_MOUSE
NC score	0.143570 (rank : 348)	θ value	0.125558 (rank : 162)
Query Neighborhood Hits	281	Target Neighborhood Hits	129	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

HCFC2_MOUSE
NC score	0.143386 (rank : 349)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	281	Target Neighborhood Hits	97	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

PGFRA_MOUSE
NC score	0.143061 (rank : 350)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	281	Target Neighborhood Hits	975	Shared Neighborhood Hits	152
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PVRL2_MOUSE
NC score	0.141591 (rank : 351)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	281	Target Neighborhood Hits	242	Shared Neighborhood Hits	88
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

KIT_MOUSE
NC score	0.140957 (rank : 352)	θ value	1.38821 (rank : 209)
Query Neighborhood Hits	281	Target Neighborhood Hits	949	Shared Neighborhood Hits	147
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

PGFRB_MOUSE
NC score	0.140222 (rank : 353)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	281	Target Neighborhood Hits	960	Shared Neighborhood Hits	145
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

CD80_HUMAN
NC score	0.139330 (rank : 354)	θ value	4.03905 (rank : 240)
Query Neighborhood Hits	281	Target Neighborhood Hits	129	Shared Neighborhood Hits	71
SwissProt Accessions	P33681	Gene names	CD80, CD28LG, CD28LG1, LAB7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7.1) (B7) (BB1).

IBP6_HUMAN
NC score	0.138510 (rank : 355)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	281	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

WISP3_HUMAN
NC score	0.138378 (rank : 356)	θ value	0.279714 (rank : 183)
Query Neighborhood Hits	281	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

CSF1R_HUMAN
NC score	0.136262 (rank : 357)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	281	Target Neighborhood Hits	943	Shared Neighborhood Hits	144
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

TENN_MOUSE
NC score	0.135666 (rank : 358)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	281	Target Neighborhood Hits	484	Shared Neighborhood Hits	85
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CTGF_MOUSE
NC score	0.135297 (rank : 359)	θ value	0.125558 (rank : 159)
Query Neighborhood Hits	281	Target Neighborhood Hits	124	Shared Neighborhood Hits	37
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

PTPRT_MOUSE
NC score	0.135038 (rank : 360)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	281	Target Neighborhood Hits	219	Shared Neighborhood Hits	65
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

JAML1_MOUSE
NC score	0.134769 (rank : 361)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	281	Target Neighborhood Hits	185	Shared Neighborhood Hits	91
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

HHLA2_HUMAN
NC score	0.134749 (rank : 362)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	281	Target Neighborhood Hits	140	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

KIT_HUMAN
NC score	0.134257 (rank : 363)	θ value	1.38821 (rank : 208)
Query Neighborhood Hits	281	Target Neighborhood Hits	953	Shared Neighborhood Hits	138
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

PTPRT_HUMAN
NC score	0.134144 (rank : 364)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	281	Target Neighborhood Hits	217	Shared Neighborhood Hits	63
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PVRL2_HUMAN
NC score	0.132785 (rank : 365)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	281	Target Neighborhood Hits	185	Shared Neighborhood Hits	85
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

IBP6_MOUSE
NC score	0.132431 (rank : 366)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	281	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

TENR_HUMAN
NC score	0.132100 (rank : 367)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	281	Target Neighborhood Hits	526	Shared Neighborhood Hits	90
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

PGFRB_HUMAN
NC score	0.130887 (rank : 368)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	281	Target Neighborhood Hits	962	Shared Neighborhood Hits	144
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

CSF3R_HUMAN
NC score	0.127683 (rank : 369)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	281	Target Neighborhood Hits	140	Shared Neighborhood Hits	47
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

TICN1_MOUSE
NC score	0.127016 (rank : 370)	θ value	0.813845 (rank : 199)
Query Neighborhood Hits	281	Target Neighborhood Hits	79	Shared Neighborhood Hits	43
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

CD79A_HUMAN
NC score	0.126929 (rank : 371)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	281	Target Neighborhood Hits	102	Shared Neighborhood Hits	58
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

MFAP3_HUMAN
NC score	0.126451 (rank : 372)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	281	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	P55082, Q9NXA7	Gene names	MFAP3
Domain Architecture
Description	Microfibril-associated glycoprotein 3 precursor.

TENR_MOUSE
NC score	0.126020 (rank : 373)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	281	Target Neighborhood Hits	531	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

RECK_MOUSE
NC score	0.125989 (rank : 374)	θ value	0.0736092 (rank : 148)
Query Neighborhood Hits	281	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

FCERA_HUMAN
NC score	0.125934 (rank : 375)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	281	Target Neighborhood Hits	150	Shared Neighborhood Hits	82
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

SORL_HUMAN
NC score	0.125370 (rank : 376)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	281	Target Neighborhood Hits	440	Shared Neighborhood Hits	74
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

RECK_HUMAN
NC score	0.125341 (rank : 377)	θ value	0.21417 (rank : 175)
Query Neighborhood Hits	281	Target Neighborhood Hits	189	Shared Neighborhood Hits	38
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

TICN3_MOUSE
NC score	0.125081 (rank : 378)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	281	Target Neighborhood Hits	83	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

LAG3_MOUSE
NC score	0.124643 (rank : 379)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	281	Target Neighborhood Hits	117	Shared Neighborhood Hits	66
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

TIE1_MOUSE
NC score	0.124180 (rank : 380)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	281	Target Neighborhood Hits	1266	Shared Neighborhood Hits	150
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CEAM7_HUMAN
NC score	0.124177 (rank : 381)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	281	Target Neighborhood Hits	170	Shared Neighborhood Hits	99
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

OX2G_MOUSE
NC score	0.123350 (rank : 382)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	281	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O54901, O54816, Q9JHD5	Gene names	Cd200, Mox2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen).

NOV_MOUSE
NC score	0.123080 (rank : 383)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	281	Target Neighborhood Hits	130	Shared Neighborhood Hits	38
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

SORL_MOUSE
NC score	0.123041 (rank : 384)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	281	Target Neighborhood Hits	439	Shared Neighborhood Hits	72
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

PDL2_HUMAN
NC score	0.122282 (rank : 385)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	281	Target Neighborhood Hits	114	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

TICN3_HUMAN
NC score	0.121738 (rank : 386)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	281	Target Neighborhood Hits	82	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

PTPRU_HUMAN
NC score	0.121168 (rank : 387)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	281	Target Neighborhood Hits	237	Shared Neighborhood Hits	79
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRK_MOUSE
NC score	0.120727 (rank : 388)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	281	Target Neighborhood Hits	223	Shared Neighborhood Hits	73
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

COEA1_HUMAN
NC score	0.120391 (rank : 389)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	281	Target Neighborhood Hits	427	Shared Neighborhood Hits	63
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

PTPRK_HUMAN
NC score	0.119477 (rank : 390)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	281	Target Neighborhood Hits	228	Shared Neighborhood Hits	73
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

CO7A1_HUMAN
NC score	0.118788 (rank : 391)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	281	Target Neighborhood Hits	807	Shared Neighborhood Hits	74
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

MFAP3_MOUSE
NC score	0.117970 (rank : 392)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	281	Target Neighborhood Hits	97	Shared Neighborhood Hits	73
SwissProt Accessions	Q922T2, Q8BHK5	Gene names	Mfap3
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 3 precursor.

TIE1_HUMAN
NC score	0.117871 (rank : 393)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	281	Target Neighborhood Hits	1241	Shared Neighborhood Hits	132
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

IPK1_HUMAN
NC score	0.117528 (rank : 394)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	281	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

TICN1_HUMAN
NC score	0.117011 (rank : 395)	θ value	5.27518 (rank : 257)
Query Neighborhood Hits	281	Target Neighborhood Hits	70	Shared Neighborhood Hits	38
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TENN_HUMAN
NC score	0.116528 (rank : 396)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	281	Target Neighborhood Hits	453	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

LAG3_HUMAN
NC score	0.115828 (rank : 397)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	281	Target Neighborhood Hits	129	Shared Neighborhood Hits	56
SwissProt Accessions	P18627	Gene names	LAG3, FDC
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (FDC protein) (CD223 antigen).

TENX_HUMAN
NC score	0.115622 (rank : 398)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	281	Target Neighborhood Hits	789	Shared Neighborhood Hits	105
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

FCGR1_HUMAN
NC score	0.113894 (rank : 399)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	281	Target Neighborhood Hits	145	Shared Neighborhood Hits	75
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

OX2G_HUMAN
NC score	0.112481 (rank : 400)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	281	Target Neighborhood Hits	100	Shared Neighborhood Hits	59
SwissProt Accessions	P41217, Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3	Gene names	CD200, MOX2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (CD200 antigen).

COKA1_HUMAN
NC score	0.112372 (rank : 401)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	281	Target Neighborhood Hits	403	Shared Neighborhood Hits	55
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CD80_MOUSE
NC score	0.110896 (rank : 402)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	281	Target Neighborhood Hits	136	Shared Neighborhood Hits	70
SwissProt Accessions	Q00609, Q61332	Gene names	Cd80, B7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (B7).

TARSH_HUMAN
NC score	0.110696 (rank : 403)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	281	Target Neighborhood Hits	768	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

FPRP_HUMAN
NC score	0.110313 (rank : 404)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	281	Target Neighborhood Hits	130	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P2B2, Q8N2K6	Gene names	PTGFRN, CD9P1, FPRP, KIAA1436
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD9 partner 1) (CD9P-1) (CD315 antigen).

CSF3R_MOUSE
NC score	0.110081 (rank : 405)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	281	Target Neighborhood Hits	104	Shared Neighborhood Hits	44
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

ILRL1_MOUSE
NC score	0.109805 (rank : 406)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	281	Target Neighborhood Hits	172	Shared Neighborhood Hits	98
SwissProt Accessions	P14719, Q05208	Gene names	Il1rl1, Ly84, St2, Ste2
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein) (T1 protein) (Lymphocyte antigen 84).

TIE2_MOUSE
NC score	0.109079 (rank : 407)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	281	Target Neighborhood Hits	1204	Shared Neighborhood Hits	113
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TIE2_HUMAN
NC score	0.108360 (rank : 408)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	281	Target Neighborhood Hits	1192	Shared Neighborhood Hits	115
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

SHPS1_HUMAN
NC score	0.108104 (rank : 409)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	281	Target Neighborhood Hits	455	Shared Neighborhood Hits	87
SwissProt Accessions	P78324, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9	Gene names	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (Sirp-alpha-2) (Sirp-alpha- 3) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusion receptor) (p84) (CD172a antigen).

BTNL2_HUMAN
NC score	0.106150 (rank : 410)	θ value	1.38821 (rank : 206)
Query Neighborhood Hits	281	Target Neighborhood Hits	164	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

TENA_HUMAN
NC score	0.105480 (rank : 411)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	281	Target Neighborhood Hits	631	Shared Neighborhood Hits	96
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

IGSF2_HUMAN
NC score	0.104902 (rank : 412)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	281	Target Neighborhood Hits	208	Shared Neighborhood Hits	70
SwissProt Accessions	Q93033, Q15856	Gene names	IGSF2, CD101, EWI101, V7
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 2 precursor (Glu-Trp-Ile EWI motif- containing protein 101) (EWI-101) (Cell surface glycoprotein V7) (CD101 antigen).

ROS_HUMAN
NC score	0.104860 (rank : 413)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	281	Target Neighborhood Hits	907	Shared Neighborhood Hits	92
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

WISP1_MOUSE
NC score	0.104231 (rank : 414)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	281	Target Neighborhood Hits	123	Shared Neighborhood Hits	33
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

CT075_HUMAN
NC score	0.103650 (rank : 415)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	281	Target Neighborhood Hits	387	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

LCE1E_HUMAN
NC score	0.102253 (rank : 416)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	281	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

AMGO2_HUMAN
NC score	0.101053 (rank : 417)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	281	Target Neighborhood Hits	357	Shared Neighborhood Hits	101
SwissProt Accessions	Q86SJ2, Q7Z4A0, Q96CN8	Gene names	AMIGO2, ALI1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA).

FLT3_MOUSE
NC score	0.099995 (rank : 418)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	281	Target Neighborhood Hits	847	Shared Neighborhood Hits	80
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

ICAM1_MOUSE
NC score	0.098989 (rank : 419)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	281	Target Neighborhood Hits	99	Shared Neighborhood Hits	73
SwissProt Accessions	P13597, Q61828	Gene names	Icam1, Icam-1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (MALA-2).

NTRK1_HUMAN
NC score	0.098712 (rank : 420)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	281	Target Neighborhood Hits	1023	Shared Neighborhood Hits	127
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

LCE1C_HUMAN
NC score	0.098421 (rank : 421)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	281	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

ISK3_MOUSE
NC score	0.097614 (rank : 422)	θ value	5.27518 (rank : 251)
Query Neighborhood Hits	281	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

TENA_MOUSE
NC score	0.097270 (rank : 423)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	281	Target Neighborhood Hits	596	Shared Neighborhood Hits	93
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

EPHB6_HUMAN
NC score	0.097039 (rank : 424)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	281	Target Neighborhood Hits	912	Shared Neighborhood Hits	96
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

IGSF8_HUMAN
NC score	0.096568 (rank : 425)	θ value	1.81305 (rank : 217)
Query Neighborhood Hits	281	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	Q969P0, Q8NG09, Q96DP4, Q9BTG9	Gene names	IGSF8, CD81P3, EWI2, KCT4
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (LIR-D1) (CD316 antigen).

EPHA7_HUMAN
NC score	0.095320 (rank : 426)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	281	Target Neighborhood Hits	1053	Shared Neighborhood Hits	92
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA8_MOUSE
NC score	0.094203 (rank : 427)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	281	Target Neighborhood Hits	969	Shared Neighborhood Hits	96
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

IGSF8_MOUSE
NC score	0.094187 (rank : 428)	θ value	1.06291 (rank : 202)
Query Neighborhood Hits	281	Target Neighborhood Hits	94	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R366, Q8R0L7	Gene names	Igsf8, Ewi2, Kct4, Pgrl
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (Prostaglandin regulatory- like protein) (CD316 antigen).

ICAM1_HUMAN
NC score	0.094127 (rank : 429)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	281	Target Neighborhood Hits	80	Shared Neighborhood Hits	54
SwissProt Accessions	P05362, Q96B50	Gene names	ICAM1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (Major group rhinovirus receptor) (CD54 antigen).

FPRP_MOUSE
NC score	0.094048 (rank : 430)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	281	Target Neighborhood Hits	116	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WV91	Gene names	Ptgfrn, Fprp
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD315 antigen).

EPHA7_MOUSE
NC score	0.093814 (rank : 431)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	281	Target Neighborhood Hits	1025	Shared Neighborhood Hits	91
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

AMGO3_HUMAN
NC score	0.093315 (rank : 432)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	281	Target Neighborhood Hits	276	Shared Neighborhood Hits	70
SwissProt Accessions	Q86WK7, Q96JH6	Gene names	AMIGO3, ALI3, KIAA1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

EPHB6_MOUSE
NC score	0.093197 (rank : 433)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	281	Target Neighborhood Hits	906	Shared Neighborhood Hits	91
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPHB3_HUMAN
NC score	0.093176 (rank : 434)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	281	Target Neighborhood Hits	996	Shared Neighborhood Hits	96
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHB3_MOUSE
NC score	0.092758 (rank : 435)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	281	Target Neighborhood Hits	996	Shared Neighborhood Hits	95
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

AMGO2_MOUSE
NC score	0.092589 (rank : 436)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	281	Target Neighborhood Hits	329	Shared Neighborhood Hits	81
SwissProt Accessions	Q80ZD9	Gene names	Amigo2, Ali1
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 2 precursor (AMIGO-2) (Alivin-1).

EPHA3_MOUSE
NC score	0.092514 (rank : 437)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	281	Target Neighborhood Hits	1009	Shared Neighborhood Hits	101
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

SIRB1_HUMAN
NC score	0.092082 (rank : 438)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	281	Target Neighborhood Hits	422	Shared Neighborhood Hits	77
SwissProt Accessions	O00241, Q5TFR0, Q8TB12, Q9H1U5, Q9Y4V0	Gene names	SIRPB1
Domain Architecture
Description	Signal-regulatory protein beta-1 precursor (SIRP-beta-1) (CD172b antigen).

HCFC2_HUMAN
NC score	0.092006 (rank : 439)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	281	Target Neighborhood Hits	154	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

EPHA8_HUMAN
NC score	0.091942 (rank : 440)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	281	Target Neighborhood Hits	956	Shared Neighborhood Hits	94
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA3_HUMAN
NC score	0.091383 (rank : 441)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	281	Target Neighborhood Hits	1005	Shared Neighborhood Hits	102
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

MT4_HUMAN
NC score	0.091374 (rank : 442)	θ value	1.06291 (rank : 204)
Query Neighborhood Hits	281	Target Neighborhood Hits	83	Shared Neighborhood Hits	11
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

LCE1D_HUMAN
NC score	0.091028 (rank : 443)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	281	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

SIGIR_MOUSE
NC score	0.089708 (rank : 444)	θ value	1.81305 (rank : 220)
Query Neighborhood Hits	281	Target Neighborhood Hits	95	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JLZ8, Q52L48	Gene names	Sigirr, Tir8
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

WISP1_HUMAN
NC score	0.089611 (rank : 445)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	281	Target Neighborhood Hits	121	Shared Neighborhood Hits	29
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

EMB_HUMAN
NC score	0.089483 (rank : 446)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	281	Target Neighborhood Hits	54	Shared Neighborhood Hits	36
SwissProt Accessions	Q6PCB8	Gene names	EMB
Domain Architecture	No domain graphic available
Description	Embigin precursor.

ILRL2_HUMAN
NC score	0.089330 (rank : 447)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	281	Target Neighborhood Hits	112	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HB29, Q13525, Q45H74	Gene names	IL1RL2, IL1RRP2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2) (Interleukin-1 receptor-related protein 2) (IL1R-rp2).

EPHA4_MOUSE
NC score	0.089187 (rank : 448)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	281	Target Neighborhood Hits	982	Shared Neighborhood Hits	91
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHB4_MOUSE
NC score	0.089142 (rank : 449)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	281	Target Neighborhood Hits	1013	Shared Neighborhood Hits	91
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

AMGO3_MOUSE
NC score	0.088168 (rank : 450)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	281	Target Neighborhood Hits	276	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C2S7, Q6ZPH1, Q8CEB3	Gene names	Amigo3, Ali3, Kiaa1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

EPHA5_HUMAN
NC score	0.087701 (rank : 451)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	281	Target Neighborhood Hits	1009	Shared Neighborhood Hits	94
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHA4_HUMAN
NC score	0.087369 (rank : 452)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	281	Target Neighborhood Hits	975	Shared Neighborhood Hits	89
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

FCGR1_MOUSE
NC score	0.086741 (rank : 453)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	281	Target Neighborhood Hits	123	Shared Neighborhood Hits	60
SwissProt Accessions	P26151	Gene names	Fcgr1, Fcg1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I).

EPHB4_HUMAN
NC score	0.086613 (rank : 454)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	281	Target Neighborhood Hits	1056	Shared Neighborhood Hits	96
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

ICAM3_HUMAN
NC score	0.086341 (rank : 455)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	281	Target Neighborhood Hits	100	Shared Neighborhood Hits	66
SwissProt Accessions	P32942	Gene names	ICAM3
Domain Architecture
Description	Intercellular adhesion molecule 3 precursor (ICAM-3) (ICAM-R) (CDw50) (CD50 antigen).

MOX2R_HUMAN
NC score	0.086228 (rank : 456)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	281	Target Neighborhood Hits	51	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TD46, Q8TD44, Q8TD45, Q8TD52	Gene names	CD200R1, CD200R, CRTR2, MOX2R, OX2R
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

ANKF1_HUMAN
NC score	0.085821 (rank : 457)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	281	Target Neighborhood Hits	126	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

I12R1_HUMAN
NC score	0.085148 (rank : 458)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	281	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

IPK2_HUMAN
NC score	0.084585 (rank : 459)	θ value	4.03905 (rank : 241)
Query Neighborhood Hits	281	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

EPHB1_HUMAN
NC score	0.084525 (rank : 460)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	281	Target Neighborhood Hits	988	Shared Neighborhood Hits	87
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

FLT3_HUMAN
NC score	0.084145 (rank : 461)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	281	Target Neighborhood Hits	843	Shared Neighborhood Hits	70
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

EPHB2_MOUSE
NC score	0.083842 (rank : 462)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	281	Target Neighborhood Hits	982	Shared Neighborhood Hits	85
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB2_HUMAN
NC score	0.083724 (rank : 463)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	281	Target Neighborhood Hits	983	Shared Neighborhood Hits	85
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

SIGL9_HUMAN
NC score	0.083192 (rank : 464)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	281	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y336, Q9BYI9	Gene names	SIGLEC9
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 9 precursor (Siglec-9) (Protein FOAP-9).

INSRR_MOUSE
NC score	0.083016 (rank : 465)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	281	Target Neighborhood Hits	961	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

I11RB_MOUSE
NC score	0.082984 (rank : 466)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	281	Target Neighborhood Hits	101	Shared Neighborhood Hits	50
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

ISK5_HUMAN
NC score	0.082972 (rank : 467)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	281	Target Neighborhood Hits	89	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

CT075_MOUSE
NC score	0.082922 (rank : 468)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	281	Target Neighborhood Hits	358	Shared Neighborhood Hits	55
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

CD4_HUMAN
NC score	0.082700 (rank : 469)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	281	Target Neighborhood Hits	122	Shared Neighborhood Hits	43
SwissProt Accessions	P01730, Q4ZGK2, Q5U066	Gene names	CD4
Domain Architecture
Description	T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3).

EPHA2_HUMAN
NC score	0.082485 (rank : 470)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	281	Target Neighborhood Hits	1021	Shared Neighborhood Hits	88
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

LCE1B_HUMAN
NC score	0.082286 (rank : 471)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	281	Target Neighborhood Hits	58	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

MT4_MOUSE
NC score	0.082239 (rank : 472)	θ value	1.06291 (rank : 205)
Query Neighborhood Hits	281	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

INSRR_HUMAN
NC score	0.082197 (rank : 473)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	281	Target Neighborhood Hits	950	Shared Neighborhood Hits	69
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

RIMB2_HUMAN
NC score	0.082073 (rank : 474)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	281	Target Neighborhood Hits	263	Shared Neighborhood Hits	37
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

TPSNR_MOUSE
NC score	0.081807 (rank : 475)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	281	Target Neighborhood Hits	336	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VD31	Gene names	Tapbpl
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

BT3A2_HUMAN
NC score	0.080785 (rank : 476)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	281	Target Neighborhood Hits	158	Shared Neighborhood Hits	70
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

I11RA_HUMAN
NC score	0.078962 (rank : 477)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	281	Target Neighborhood Hits	138	Shared Neighborhood Hits	47
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

EPHA5_MOUSE
NC score	0.078739 (rank : 478)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	281	Target Neighborhood Hits	950	Shared Neighborhood Hits	84
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

IGF1R_HUMAN
NC score	0.078096 (rank : 479)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	281	Target Neighborhood Hits	977	Shared Neighborhood Hits	76
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

EPHA2_MOUSE
NC score	0.077949 (rank : 480)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	281	Target Neighborhood Hits	1020	Shared Neighborhood Hits	86
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

RIMB2_MOUSE
NC score	0.077933 (rank : 481)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	281	Target Neighborhood Hits	246	Shared Neighborhood Hits	32
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

INSR_MOUSE
NC score	0.077465 (rank : 482)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	281	Target Neighborhood Hits	968	Shared Neighborhood Hits	63
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

AMGO1_HUMAN
NC score	0.077188 (rank : 483)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	281	Target Neighborhood Hits	353	Shared Neighborhood Hits	76
SwissProt Accessions	Q86WK6, Q8IW71, Q9ULQ7	Gene names	AMIGO1, ALI2, AMIGO, KIAA1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

IGF1R_MOUSE
NC score	0.077129 (rank : 484)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	281	Target Neighborhood Hits	973	Shared Neighborhood Hits	74
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

I11RA_MOUSE
NC score	0.077110 (rank : 485)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	281	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

PTPRB_HUMAN
NC score	0.076285 (rank : 486)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	281	Target Neighborhood Hits	242	Shared Neighborhood Hits	46
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

TPSNR_HUMAN
NC score	0.075264 (rank : 487)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	281	Target Neighborhood Hits	330	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BX59, Q9NWB8	Gene names	TAPBPL
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

ISK4_HUMAN
NC score	0.074244 (rank : 488)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	281	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

INSR_HUMAN
NC score	0.074100 (rank : 489)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	281	Target Neighborhood Hits	963	Shared Neighborhood Hits	62
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

FCRLA_HUMAN
NC score	0.073835 (rank : 490)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	281	Target Neighborhood Hits	135	Shared Neighborhood Hits	41
SwissProt Accessions	Q7L513, Q5VXA1, Q5VXA2, Q5VXA3, Q5VXB0, Q8NEW4, Q8WXH3, Q96PC6, Q96PJ0, Q96PJ1, Q96PJ2, Q96PJ4, Q9BR57	Gene names	FCRLA, FCRL, FCRL1, FCRLM1, FCRX, FREB
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

EPHA6_HUMAN
NC score	0.073805 (rank : 491)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	281	Target Neighborhood Hits	959	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

JAML1_HUMAN
NC score	0.073746 (rank : 492)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	281	Target Neighborhood Hits	108	Shared Neighborhood Hits	45
SwissProt Accessions	Q86YT9, Q5DTC6, Q7Z499, Q8N9I7, Q8NF70	Gene names	AMICA1, JAML
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (Dendritic cell-specific protein CREA7-1) (Adhesion molecule interacting with CXADR antigen 1).

EPHAA_HUMAN
NC score	0.073333 (rank : 493)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	281	Target Neighborhood Hits	960	Shared Neighborhood Hits	79
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

FCRLA_MOUSE
NC score	0.072990 (rank : 494)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	281	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q920A9, Q3T9Q2, Q8K3U9, Q8VHP5	Gene names	Fcrla, Fcrl, Fcrl1, Fcrlm1, Fcrx, Freb
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

IL27B_HUMAN
NC score	0.072019 (rank : 495)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	281	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

I12R1_MOUSE
NC score	0.071601 (rank : 496)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	281	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

FCG2B_HUMAN
NC score	0.070373 (rank : 497)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	281	Target Neighborhood Hits	116	Shared Neighborhood Hits	44
SwissProt Accessions	P31994, O95649, Q53X85, Q5VXA9, Q8NIA1	Gene names	FCGR2B, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-b precursor (Fc-gamma RII-b) (FcRII-b) (IgG Fc receptor II-b) (Fc-gamma-RIIb) (CD32 antigen) (CDw32).

FCG2C_HUMAN
NC score	0.070341 (rank : 498)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	281	Target Neighborhood Hits	118	Shared Neighborhood Hits	46
SwissProt Accessions	P31995, O00523, O00524, O00525	Gene names	FCGR2C, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-c precursor (Fc-gamma RII-c) (FcRII-c) (IgG Fc receptor II-c) (Fc-gamma-RIIc) (CD32 antigen) (CDw32).

BT1A1_MOUSE
NC score	0.070013 (rank : 499)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	281	Target Neighborhood Hits	252	Shared Neighborhood Hits	87
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

EPHA1_MOUSE
NC score	0.069584 (rank : 500)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	281	Target Neighborhood Hits	958	Shared Neighborhood Hits	86
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA6_MOUSE
NC score	0.069012 (rank : 501)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	281	Target Neighborhood Hits	946	Shared Neighborhood Hits	72
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

ISK7_HUMAN
NC score	0.068758 (rank : 502)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	281	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

IL6RA_MOUSE
NC score	0.068630 (rank : 503)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	281	Target Neighborhood Hits	104	Shared Neighborhood Hits	43
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

SPRL1_HUMAN
NC score	0.068238 (rank : 504)	θ value	5.27518 (rank : 256)
Query Neighborhood Hits	281	Target Neighborhood Hits	231	Shared Neighborhood Hits	30
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

A1BG_HUMAN
NC score	0.067517 (rank : 505)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	281	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	P04217, Q8IYJ6, Q96P39	Gene names	A1BG
Domain Architecture
Description	Alpha-1B-glycoprotein precursor (Alpha-1-B glycoprotein).

AMGO1_MOUSE
NC score	0.067504 (rank : 506)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	281	Target Neighborhood Hits	325	Shared Neighborhood Hits	65
SwissProt Accessions	Q80ZD8, Q69ZQ0, Q8R5D4, Q921U9	Gene names	Amigo1, Ali2, Amigo, Kiaa1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

GP125_MOUSE
NC score	0.067341 (rank : 507)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	281	Target Neighborhood Hits	329	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

PTPRJ_HUMAN
NC score	0.066674 (rank : 508)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	281	Target Neighborhood Hits	207	Shared Neighborhood Hits	35
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
NC score	0.066156 (rank : 509)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	281	Target Neighborhood Hits	188	Shared Neighborhood Hits	32
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

EPHA1_HUMAN
NC score	0.066044 (rank : 510)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	281	Target Neighborhood Hits	997	Shared Neighborhood Hits	77
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

GP125_HUMAN
NC score	0.065622 (rank : 511)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	281	Target Neighborhood Hits	327	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

PTPRO_HUMAN
NC score	0.064699 (rank : 512)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	281	Target Neighborhood Hits	139	Shared Neighborhood Hits	26
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRV_MOUSE
NC score	0.064302 (rank : 513)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	281	Target Neighborhood Hits	179	Shared Neighborhood Hits	35
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

SHPS1_MOUSE
NC score	0.064012 (rank : 514)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	281	Target Neighborhood Hits	439	Shared Neighborhood Hits	68
SwissProt Accessions	P97797, O08907, O35924, O88555, O88556, P97796, Q8R559, Q9QX57, Q9WTN4	Gene names	Sirpa, Bit, Myd1, Ptpns1, Shps1, Sirp
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (p84) (CD172a antigen).

STYK1_MOUSE
NC score	0.063235 (rank : 515)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	281	Target Neighborhood Hits	779	Shared Neighborhood Hits	33
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

BT1A1_HUMAN
NC score	0.063145 (rank : 516)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	281	Target Neighborhood Hits	322	Shared Neighborhood Hits	83
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

SIRPG_HUMAN
NC score	0.063122 (rank : 517)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	281	Target Neighborhood Hits	359	Shared Neighborhood Hits	64
SwissProt Accessions	Q9P1W8, Q8WWA5, Q9NQK8	Gene names	SIRPG, SIRPB2
Domain Architecture
Description	Signal-regulatory protein gamma precursor (Signal-regulatory protein beta-2) (SIRP-beta-2) (SIRP-b2) (CD172g antigen).

BTNL1_MOUSE
NC score	0.063109 (rank : 518)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	281	Target Neighborhood Hits	151	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

STYK1_HUMAN
NC score	0.062915 (rank : 519)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	281	Target Neighborhood Hits	786	Shared Neighborhood Hits	35
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

TMM25_MOUSE
NC score	0.062193 (rank : 520)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	281	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DCF1, Q3TMP3, Q6PAK7	Gene names	Tmem25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

VASN_HUMAN
NC score	0.061753 (rank : 521)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	281	Target Neighborhood Hits	449	Shared Neighborhood Hits	38
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VASN_MOUSE
NC score	0.061247 (rank : 522)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	281	Target Neighborhood Hits	426	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

FCG2A_HUMAN
NC score	0.060882 (rank : 523)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	281	Target Neighborhood Hits	92	Shared Neighborhood Hits	39
SwissProt Accessions	P12318	Gene names	FCGR2A, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-a precursor (Fc-gamma RII-a) (FcRII-a) (IgG Fc receptor II-a) (Fc-gamma-RIIa) (CD32 antigen) (CDw32).

HG2A_MOUSE
NC score	0.060726 (rank : 524)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	281	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

CRLF1_HUMAN
NC score	0.060554 (rank : 525)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	281	Target Neighborhood Hits	122	Shared Neighborhood Hits	34
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

NYX_MOUSE
NC score	0.060526 (rank : 526)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	281	Target Neighborhood Hits	241	Shared Neighborhood Hits	26
SwissProt Accessions	P83503, Q8BYN4	Gene names	Nyx
Domain Architecture
Description	Nyctalopin precursor.

SPRC_MOUSE
NC score	0.060370 (rank : 527)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	281	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_HUMAN
NC score	0.060323 (rank : 528)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	281	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

RET_MOUSE
NC score	0.059519 (rank : 529)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	281	Target Neighborhood Hits	884	Shared Neighborhood Hits	35
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

CHAD_HUMAN
NC score	0.059515 (rank : 530)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	281	Target Neighborhood Hits	267	Shared Neighborhood Hits	26
SwissProt Accessions	O15335, Q96RJ5	Gene names	CHAD
Domain Architecture
Description	Chondroadherin precursor (Cartilage leucine-rich protein).

ISK7_MOUSE
NC score	0.059418 (rank : 531)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	281	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

SLIT2_MOUSE
NC score	0.059372 (rank : 532)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	281	Target Neighborhood Hits	684	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

RET_HUMAN
NC score	0.059321 (rank : 533)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	281	Target Neighborhood Hits	873	Shared Neighborhood Hits	32
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

LY9_MOUSE
NC score	0.059288 (rank : 534)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	281	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q01965, Q9ES29, Q9ES35, Q9ES36	Gene names	Ly9, Ly-9
Domain Architecture
Description	T-lymphocyte surface antigen Ly-9 precursor (Lymphocyte antigen 9) (Cell-surface molecule Ly-9).

NYX_HUMAN
NC score	0.059192 (rank : 535)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	281	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	Q9GZU5, Q5H983, Q9H4J0	Gene names	NYX, CLRP
Domain Architecture
Description	Nyctalopin precursor.

SLIT2_HUMAN
NC score	0.059070 (rank : 536)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	281	Target Neighborhood Hits	708	Shared Neighborhood Hits	58
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

GP116_HUMAN
NC score	0.058984 (rank : 537)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	281	Target Neighborhood Hits	167	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

RYK_HUMAN
NC score	0.058315 (rank : 538)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	281	Target Neighborhood Hits	701	Shared Neighborhood Hits	31
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

CHAD_MOUSE
NC score	0.058182 (rank : 539)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	281	Target Neighborhood Hits	260	Shared Neighborhood Hits	26
SwissProt Accessions	O55226	Gene names	Chad
Domain Architecture
Description	Chondroadherin precursor (Cartilage leucine-rich protein).

R4RL2_HUMAN
NC score	0.058117 (rank : 540)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	281	Target Neighborhood Hits	273	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UN3, Q6X813	Gene names	RTN4RL2, NGRH1, NGRL3
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 2 precursor (Nogo-66 receptor homolog 1) (Nogo-66 receptor-related protein 2) (NgR2) (Nogo receptor-like 3).

I27RA_HUMAN
NC score	0.058064 (rank : 541)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	281	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

SLIT1_HUMAN
NC score	0.057999 (rank : 542)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	281	Target Neighborhood Hits	700	Shared Neighborhood Hits	56
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

LTK_HUMAN
NC score	0.057945 (rank : 543)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	281	Target Neighborhood Hits	774	Shared Neighborhood Hits	34
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

R4RL2_MOUSE
NC score	0.057943 (rank : 544)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	281	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q7M6Z0, Q3UQ62	Gene names	Rtn4rl2, Ngrl3
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 2 precursor (Nogo-66 receptor homolog 1) (Nogo-66 receptor-related protein 2) (NgR2) (Nogo receptor-like 3).

RTN4R_HUMAN
NC score	0.057792 (rank : 545)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	281	Target Neighborhood Hits	271	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZR6	Gene names	RTN4R, NOGOR
Domain Architecture
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

LTK_MOUSE
NC score	0.057673 (rank : 546)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	281	Target Neighborhood Hits	770	Shared Neighborhood Hits	34
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

SLIT1_MOUSE
NC score	0.057659 (rank : 547)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	281	Target Neighborhood Hits	715	Shared Neighborhood Hits	55
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

RYK_MOUSE
NC score	0.057520 (rank : 548)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	281	Target Neighborhood Hits	715	Shared Neighborhood Hits	30
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

FLRT1_HUMAN
NC score	0.057430 (rank : 549)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	281	Target Neighborhood Hits	286	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NZU1	Gene names	FLRT1
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT1 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 1).

CD33_MOUSE
NC score	0.057410 (rank : 550)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	281	Target Neighborhood Hits	45	Shared Neighborhood Hits	21
SwissProt Accessions	Q63994, Q63997	Gene names	Cd33
Domain Architecture
Description	Myeloid cell surface antigen CD33 precursor (Siglec-3).

ALS_HUMAN
NC score	0.056639 (rank : 551)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	281	Target Neighborhood Hits	280	Shared Neighborhood Hits	27
SwissProt Accessions	P35858	Gene names	IGFALS, ALS
Domain Architecture
Description	Insulin-like growth factor-binding protein complex acid labile chain precursor (ALS).

SLIT3_HUMAN
NC score	0.056553 (rank : 552)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	281	Target Neighborhood Hits	682	Shared Neighborhood Hits	49
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

ALK_MOUSE
NC score	0.056265 (rank : 553)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	281	Target Neighborhood Hits	811	Shared Neighborhood Hits	35
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

R4RL1_HUMAN
NC score	0.056210 (rank : 554)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	281	Target Neighborhood Hits	240	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UN2, Q8ND46	Gene names	RTN4RL1, NGRH2, NGRL2
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 1 precursor (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3) (Nogo receptor-like 2).

GPV_MOUSE
NC score	0.056191 (rank : 555)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	281	Target Neighborhood Hits	293	Shared Neighborhood Hits	26
SwissProt Accessions	O08742	Gene names	Gp5
Domain Architecture	No domain graphic available
Description	Platelet glycoprotein V precursor (GPV) (CD42D antigen).

SLIT3_MOUSE
NC score	0.056175 (rank : 556)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	281	Target Neighborhood Hits	700	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

HCFC1_MOUSE
NC score	0.055939 (rank : 557)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	281	Target Neighborhood Hits	348	Shared Neighborhood Hits	38
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

TMM25_HUMAN
NC score	0.055918 (rank : 558)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	281	Target Neighborhood Hits	43	Shared Neighborhood Hits	32
SwissProt Accessions	Q86YD3, Q6UW89, Q86UA7, Q96KA6, Q96MW9	Gene names	TMEM25
Domain Architecture	No domain graphic available
Description	Transmembrane protein 25 precursor.

ALK_HUMAN
NC score	0.055743 (rank : 559)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	281	Target Neighborhood Hits	795	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

LRC15_MOUSE
NC score	0.055665 (rank : 560)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	281	Target Neighborhood Hits	305	Shared Neighborhood Hits	26
SwissProt Accessions	Q80X72	Gene names	Lrrc15
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 15 precursor.

ISK4_MOUSE
NC score	0.055570 (rank : 561)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	281	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

DDR1_MOUSE
NC score	0.055557 (rank : 562)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	281	Target Neighborhood Hits	818	Shared Neighborhood Hits	35
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

TPBG_HUMAN
NC score	0.055551 (rank : 563)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	281	Target Neighborhood Hits	238	Shared Neighborhood Hits	26
SwissProt Accessions	Q13641	Gene names	TPBG, 5T4
Domain Architecture	No domain graphic available
Description	Trophoblast glycoprotein precursor (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (5T4 oncofetal antigen) (M6P1).

FLRT2_HUMAN
NC score	0.055542 (rank : 564)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	281	Target Neighborhood Hits	295	Shared Neighborhood Hits	27
SwissProt Accessions	O43155	Gene names	FLRT2, KIAA0405
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT2 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 2).

RTN4R_MOUSE
NC score	0.055397 (rank : 565)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	281	Target Neighborhood Hits	293	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PI8, Q80WQ1	Gene names	Rtn4r, Nogor
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

CD45_MOUSE
NC score	0.055360 (rank : 566)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	281	Target Neighborhood Hits	178	Shared Neighborhood Hits	25
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

CD33_HUMAN
NC score	0.055088 (rank : 567)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	281	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	P20138, Q8TD24	Gene names	CD33
Domain Architecture
Description	Myeloid cell surface antigen CD33 precursor (Siglec-3) (gp67).

LCE1A_HUMAN
NC score	0.054861 (rank : 568)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	281	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

FLRT3_HUMAN
NC score	0.054650 (rank : 569)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	281	Target Neighborhood Hits	281	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NZU0, Q96K39, Q96K42, Q96KB1, Q9P259	Gene names	FLRT3, KIAA1469
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT3 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 3).

ALS_MOUSE
NC score	0.054528 (rank : 570)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	281	Target Neighborhood Hits	275	Shared Neighborhood Hits	26
SwissProt Accessions	P70389, Q9DBI7	Gene names	Igfals, Albs, Als
Domain Architecture
Description	Insulin-like growth factor-binding protein complex acid labile chain precursor (ALS).

DDR1_HUMAN
NC score	0.054441 (rank : 571)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	281	Target Neighborhood Hits	819	Shared Neighborhood Hits	35
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR2_HUMAN
NC score	0.054311 (rank : 572)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	281	Target Neighborhood Hits	818	Shared Neighborhood Hits	35
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

TSK_HUMAN
NC score	0.054226 (rank : 573)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	281	Target Neighborhood Hits	268	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WUA8, Q6UXK1, Q9UG10, Q9UJX9	Gene names	LRRC54, E2IG4, TSK
Domain Architecture	No domain graphic available
Description	Tsukushi precursor (Leucine-rich repeat-containing protein 54) (E2- induced gene 4 protein).

LRC15_HUMAN
NC score	0.054125 (rank : 574)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	281	Target Neighborhood Hits	305	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TF66, Q7RTN7	Gene names	LRRC15, LIB
Domain Architecture
Description	Leucine-rich repeat-containing protein 15 precursor (hLib).

GP124_HUMAN
NC score	0.054101 (rank : 575)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	281	Target Neighborhood Hits	304	Shared Neighborhood Hits	30
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

SCN2B_HUMAN
NC score	0.054079 (rank : 576)	θ value	1.38821 (rank : 213)
Query Neighborhood Hits	281	Target Neighborhood Hits	88	Shared Neighborhood Hits	20
SwissProt Accessions	O60939, O75302, Q9UNN3	Gene names	SCN2B
Domain Architecture
Description	Sodium channel beta-2 subunit precursor.

LCE4A_HUMAN
NC score	0.054033 (rank : 577)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	281	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

CD45_HUMAN
NC score	0.053856 (rank : 578)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	281	Target Neighborhood Hits	243	Shared Neighborhood Hits	22
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CPN2_HUMAN
NC score	0.053829 (rank : 579)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	281	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	P22792, Q86SU4, Q8N5V4	Gene names	CPN2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit).

R4RL1_MOUSE
NC score	0.053694 (rank : 580)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	281	Target Neighborhood Hits	235	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K0S5	Gene names	Rtn4rl1, Ngrl2
Domain Architecture	No domain graphic available
Description	Reticulon-4 receptor-like 1 precursor (Nogo-66 receptor homolog 2) (Nogo-66 receptor-related protein 3) (NgR3) (Nogo receptor-like 2).

GPV_HUMAN
NC score	0.053447 (rank : 581)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	281	Target Neighborhood Hits	284	Shared Neighborhood Hits	26
SwissProt Accessions	P40197	Gene names	GP5
Domain Architecture
Description	Platelet glycoprotein V precursor (GPV) (CD42D antigen).

GP124_MOUSE
NC score	0.053287 (rank : 582)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	281	Target Neighborhood Hits	423	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

CD244_HUMAN
NC score	0.053281 (rank : 583)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	281	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZW8, Q96T47, Q9NQD2, Q9NQD3, Q9Y288	Gene names	CD244, 2B4
Domain Architecture
Description	Natural killer cell receptor 2B4 precursor (NKR2B4) (NK cell type I receptor protein 2B4) (h2B4) (CD244 antigen) (NK cell activation- inducing ligand) (NAIL).

DDR2_MOUSE
NC score	0.053230 (rank : 584)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	281	Target Neighborhood Hits	813	Shared Neighborhood Hits	35
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

LRRK1_MOUSE
NC score	0.053063 (rank : 585)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	281	Target Neighborhood Hits	1267	Shared Neighborhood Hits	59
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

HG2A_HUMAN
NC score	0.052791 (rank : 586)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	281	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

CPN2_MOUSE
NC score	0.052731 (rank : 587)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	281	Target Neighborhood Hits	291	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBB9, Q8R113	Gene names	Cpn2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N subunit 2 precursor (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N regulatory subunit) (Carboxypeptidase N large subunit).

TPBG_MOUSE
NC score	0.052616 (rank : 588)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	281	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0L0, Q6PE98, Q8BQA4	Gene names	Tpbg, 5t4
Domain Architecture	No domain graphic available
Description	Trophoblast glycoprotein precursor (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein).

GP1BB_MOUSE
NC score	0.052414 (rank : 589)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	281	Target Neighborhood Hits	136	Shared Neighborhood Hits	26
SwissProt Accessions	P56400	Gene names	Gp1bb
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (CD42c antigen).

ACK1_MOUSE
NC score	0.052384 (rank : 590)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	281	Target Neighborhood Hits	1080	Shared Neighborhood Hits	35
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

TNK1_HUMAN
NC score	0.052352 (rank : 591)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	281	Target Neighborhood Hits	815	Shared Neighborhood Hits	33
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

CD226_HUMAN
NC score	0.052328 (rank : 592)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	281	Target Neighborhood Hits	87	Shared Neighborhood Hits	39
SwissProt Accessions	Q15762	Gene names	CD226, DNAM1
Domain Architecture
Description	CD226 antigen precursor (DNAX accessory molecule 1) (DNAM-1).

AATK_MOUSE
NC score	0.052304 (rank : 593)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	281	Target Neighborhood Hits	942	Shared Neighborhood Hits	33
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

FAK1_HUMAN
NC score	0.052201 (rank : 594)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	281	Target Neighborhood Hits	850	Shared Neighborhood Hits	33
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

IPK2_MOUSE
NC score	0.052147 (rank : 595)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	281	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BMY7	Gene names	Spink2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 2 precursor.

ACK1_HUMAN
NC score	0.052002 (rank : 596)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	281	Target Neighborhood Hits	1140	Shared Neighborhood Hits	36
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

FAK1_MOUSE
NC score	0.051906 (rank : 597)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	281	Target Neighborhood Hits	850	Shared Neighborhood Hits	33
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

LRTM1_MOUSE
NC score	0.051905 (rank : 598)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	281	Target Neighborhood Hits	264	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K377, Q3UVX1	Gene names	Lrrtm1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 1 precursor.

LRC55_HUMAN
NC score	0.051797 (rank : 599)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	281	Target Neighborhood Hits	257	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZSA7	Gene names	LRRC55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

PKD1_HUMAN
NC score	0.051676 (rank : 600)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	281	Target Neighborhood Hits	387	Shared Neighborhood Hits	31
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

LRTM2_MOUSE
NC score	0.051459 (rank : 601)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	281	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BGA3, Q80U08	Gene names	Lrrtm2, Kiaa0416
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor.

TNK1_MOUSE
NC score	0.051440 (rank : 602)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	281	Target Neighborhood Hits	806	Shared Neighborhood Hits	34
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

CRLF1_MOUSE
NC score	0.051387 (rank : 603)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	281	Target Neighborhood Hits	116	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

LRRK1_HUMAN
NC score	0.051364 (rank : 604)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	281	Target Neighborhood Hits	1237	Shared Neighborhood Hits	59
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

KSYK_MOUSE
NC score	0.051363 (rank : 605)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	281	Target Neighborhood Hits	944	Shared Neighborhood Hits	35
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_HUMAN
NC score	0.051303 (rank : 606)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	281	Target Neighborhood Hits	901	Shared Neighborhood Hits	33
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LRRC3_MOUSE
NC score	0.051239 (rank : 607)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	281	Target Neighborhood Hits	236	Shared Neighborhood Hits	26
SwissProt Accessions	P59034	Gene names	Lrrc3
Domain Architecture
Description	Leucine-rich repeat-containing protein 3 precursor.

GPIX_HUMAN
NC score	0.051229 (rank : 608)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	281	Target Neighborhood Hits	162	Shared Neighborhood Hits	26
SwissProt Accessions	P14770, Q14445, Q92525	Gene names	GP9
Domain Architecture
Description	Platelet glycoprotein IX precursor (GPIX) (CD42a antigen).

LRTM2_HUMAN
NC score	0.051213 (rank : 609)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	281	Target Neighborhood Hits	282	Shared Neighborhood Hits	26
SwissProt Accessions	O43300, Q7L770	Gene names	LRRTM2, KIAA0416, LRRN2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor (Leucine-rich repeat neuronal 2 protein).

FAK2_HUMAN
NC score	0.051210 (rank : 610)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	281	Target Neighborhood Hits	847	Shared Neighborhood Hits	33
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
NC score	0.051133 (rank : 611)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	281	Target Neighborhood Hits	851	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

AATK_HUMAN
NC score	0.051076 (rank : 612)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	281	Target Neighborhood Hits	1243	Shared Neighborhood Hits	34
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

SRMS_HUMAN
NC score	0.051065 (rank : 613)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	281	Target Neighborhood Hits	946	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

LRTM4_MOUSE
NC score	0.050890 (rank : 614)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	281	Target Neighborhood Hits	284	Shared Neighborhood Hits	28
SwissProt Accessions	Q80XG9, Q8C030, Q8JZS8	Gene names	Lrrtm4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 4 precursor.

A2GL_HUMAN
NC score	0.050878 (rank : 615)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	281	Target Neighborhood Hits	281	Shared Neighborhood Hits	27
SwissProt Accessions	P02750, Q8N4F5, Q96QZ4	Gene names	LRG1, LRG
Domain Architecture
Description	Leucine-rich alpha-2-glycoprotein precursor (LRG).

LRTM1_HUMAN
NC score	0.050840 (rank : 616)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	281	Target Neighborhood Hits	273	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UE6, Q96DN1	Gene names	LRRTM1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 1 precursor.

LRC19_MOUSE
NC score	0.050836 (rank : 617)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	281	Target Neighborhood Hits	238	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BZT5, Q6P8J1	Gene names	Lrrc19
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 19 precursor.

LRTM3_HUMAN
NC score	0.050707 (rank : 618)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	281	Target Neighborhood Hits	276	Shared Neighborhood Hits	27
SwissProt Accessions	Q86VH5, Q6N0A3	Gene names	LRRTM3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 3 precursor.

ICOSL_MOUSE
NC score	0.050630 (rank : 619)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	281	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

LRTM4_HUMAN
NC score	0.050629 (rank : 620)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	281	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q86VH4	Gene names	LRRTM4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 4 precursor.

RON_MOUSE
NC score	0.050617 (rank : 621)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	281	Target Neighborhood Hits	836	Shared Neighborhood Hits	33
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

SRMS_MOUSE
NC score	0.050576 (rank : 622)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	281	Target Neighborhood Hits	964	Shared Neighborhood Hits	33
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

RON_HUMAN
NC score	0.050567 (rank : 623)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	281	Target Neighborhood Hits	842	Shared Neighborhood Hits	35
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

LRC55_MOUSE
NC score	0.050548 (rank : 624)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	281	Target Neighborhood Hits	254	Shared Neighborhood Hits	26
SwissProt Accessions	Q3UY51	Gene names	Lrrc55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

GP1BA_HUMAN
NC score	0.050405 (rank : 625)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	281	Target Neighborhood Hits	407	Shared Neighborhood Hits	28
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

ECM2_HUMAN
NC score	0.050312 (rank : 626)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	281	Target Neighborhood Hits	402	Shared Neighborhood Hits	35
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

LRC52_HUMAN
NC score	0.050240 (rank : 627)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	281	Target Neighborhood Hits	229	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N7C0, Q5T9K5	Gene names	LRRC52
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 52 precursor.

ZAP70_MOUSE
NC score	0.050030 (rank : 628)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	281	Target Neighborhood Hits	905	Shared Neighborhood Hits	33
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

SSPO_MOUSE
NC score	0.044641 (rank : 629)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	281	Target Neighborhood Hits	800	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

BMPER_MOUSE
NC score	0.044382 (rank : 630)	θ value	2.36792 (rank : 221)
Query Neighborhood Hits	281	Target Neighborhood Hits	194	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BMPER_HUMAN
NC score	0.042331 (rank : 631)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	281	Target Neighborhood Hits	175	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

LAMA5_MOUSE
NC score	0.042209 (rank : 632)	θ value	0.279714 (rank : 179)
Query Neighborhood Hits	281	Target Neighborhood Hits	828	Shared Neighborhood Hits	34
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MOG_MOUSE
NC score	0.042102 (rank : 633)	θ value	5.27518 (rank : 252)
Query Neighborhood Hits	281	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MEGF6_HUMAN
NC score	0.031626 (rank : 634)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	281	Target Neighborhood Hits	671	Shared Neighborhood Hits	46
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KRA51_HUMAN
NC score	0.031396 (rank : 635)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	281	Target Neighborhood Hits	288	Shared Neighborhood Hits	17
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

MT2_MOUSE
NC score	0.030674 (rank : 636)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	281	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

STAB1_HUMAN
NC score	0.025089 (rank : 637)	θ value	4.03905 (rank : 247)
Query Neighborhood Hits	281	Target Neighborhood Hits	546	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

EI2BE_MOUSE
NC score	0.023456 (rank : 638)	θ value	2.36792 (rank : 223)
Query Neighborhood Hits	281	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHW4, Q3TU39	Gene names	Eif2b5
Domain Architecture	No domain graphic available
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

EI2BE_HUMAN
NC score	0.020322 (rank : 639)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	281	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q13144, Q96D04	Gene names	EIF2B5, EIF2BE
Domain Architecture
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

NOTC1_HUMAN
NC score	0.020203 (rank : 640)	θ value	5.27518 (rank : 254)
Query Neighborhood Hits	281	Target Neighborhood Hits	906	Shared Neighborhood Hits	33
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

EGFL7_HUMAN
NC score	0.019096 (rank : 641)	θ value	5.27518 (rank : 250)
Query Neighborhood Hits	281	Target Neighborhood Hits	325	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

SEM3F_HUMAN
NC score	0.016346 (rank : 642)	θ value	5.27518 (rank : 255)
Query Neighborhood Hits	281	Target Neighborhood Hits	100	Shared Neighborhood Hits	29
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

RELN_MOUSE
NC score	0.014697 (rank : 643)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	281	Target Neighborhood Hits	235	Shared Neighborhood Hits	14
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

PGCA_HUMAN
NC score	0.012506 (rank : 644)	θ value	4.03905 (rank : 244)
Query Neighborhood Hits	281	Target Neighborhood Hits	821	Shared Neighborhood Hits	39
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

ADAM8_HUMAN
NC score	0.011059 (rank : 645)	θ value	0.813845 (rank : 197)
Query Neighborhood Hits	281	Target Neighborhood Hits	327	Shared Neighborhood Hits	20
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

LV6A_HUMAN
NC score	0.001961 (rank : 646)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	281	Target Neighborhood Hits	284	Shared Neighborhood Hits	12
SwissProt Accessions	P01721	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda chain V-VI region AR.

SYNE1_HUMAN
NC score	-0.003796 (rank : 647)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	281	Target Neighborhood Hits	1484	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ZN425_HUMAN
NC score	-0.009523 (rank : 648)	θ value	3.0926 (rank : 239)
Query Neighborhood Hits	281	Target Neighborhood Hits	795	Shared Neighborhood Hits	5
SwissProt Accessions	Q6IV72	Gene names	ZNF425
Domain Architecture	No domain graphic available
Description	Zinc finger protein 425.