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Network neighborhood for query Sequence : SPRC_HUMAN

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SPRC_HUMAN
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPRC_MOUSE
θ value	2.85304e-163 (rank : 1)	NC score	0.998490 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_HUMAN
θ value	2.41524e-162 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRL1_HUMAN
θ value	8.77142e-88 (rank : 3)	NC score	0.880255 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	231	Shared Neighborhood Hits	29
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SPRL1_MOUSE
θ value	5.6855e-87 (rank : 4)	NC score	0.817838 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	403	Shared Neighborhood Hits	30
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TICN3_MOUSE
θ value	3.29651e-10 (rank : 5)	NC score	0.493575 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	83	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_HUMAN
θ value	1.38499e-08 (rank : 6)	NC score	0.481848 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	82	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN1_MOUSE
θ value	6.87365e-08 (rank : 7)	NC score	0.458819 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	79	Shared Neighborhood Hits	25
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN2_MOUSE
θ value	1.17247e-07 (rank : 8)	NC score	0.477089 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_HUMAN
θ value	7.59969e-07 (rank : 9)	NC score	0.469287 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

FST_HUMAN
θ value	2.21117e-06 (rank : 10)	NC score	0.435027 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	129	Shared Neighborhood Hits	33
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	6.43352e-06 (rank : 11)	NC score	0.425121 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	146	Shared Neighborhood Hits	34
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

TICN1_HUMAN
θ value	6.43352e-06 (rank : 12)	NC score	0.434342 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

FSTL3_HUMAN
θ value	2.44474e-05 (rank : 13)	NC score	0.429025 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

SMOC2_HUMAN
θ value	5.44631e-05 (rank : 14)	NC score	0.368289 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC1_MOUSE
θ value	9.29e-05 (rank : 15)	NC score	0.365749 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

SMOC1_HUMAN
θ value	0.000121331 (rank : 16)	NC score	0.357398 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	81	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC2_MOUSE
θ value	0.000158464 (rank : 17)	NC score	0.357769 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	81	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

AGRIN_HUMAN
θ value	0.000270298 (rank : 18)	NC score	0.199180 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	582	Shared Neighborhood Hits	42
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

FSTL3_MOUSE
θ value	0.00035302 (rank : 19)	NC score	0.405270 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	152	Shared Neighborhood Hits	35
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL1_HUMAN
θ value	0.000786445 (rank : 20)	NC score	0.381717 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
θ value	0.00134147 (rank : 21)	NC score	0.374957 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	74	Shared Neighborhood Hits	27
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

NOTC3_HUMAN
θ value	0.0113563 (rank : 22)	NC score	0.062167 (rank : 61)
Query Neighborhood Hits	45	Target Neighborhood Hits	1062	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TEFF2_HUMAN
θ value	0.0330416 (rank : 23)	NC score	0.235408 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	211	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	0.0330416 (rank : 24)	NC score	0.237921 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	214	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

NOTC1_MOUSE
θ value	0.21417 (rank : 25)	NC score	0.058141 (rank : 66)
Query Neighborhood Hits	45	Target Neighborhood Hits	916	Shared Neighborhood Hits	25
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CRUM1_MOUSE
θ value	0.279714 (rank : 26)	NC score	0.066036 (rank : 56)
Query Neighborhood Hits	45	Target Neighborhood Hits	444	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

SLIT2_HUMAN
θ value	0.279714 (rank : 27)	NC score	0.057198 (rank : 68)
Query Neighborhood Hits	45	Target Neighborhood Hits	708	Shared Neighborhood Hits	26
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	0.365318 (rank : 28)	NC score	0.056049 (rank : 73)
Query Neighborhood Hits	45	Target Neighborhood Hits	684	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

NOTC1_HUMAN
θ value	0.47712 (rank : 29)	NC score	0.055822 (rank : 74)
Query Neighborhood Hits	45	Target Neighborhood Hits	906	Shared Neighborhood Hits	25
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SLIT3_MOUSE
θ value	0.47712 (rank : 30)	NC score	0.056505 (rank : 70)
Query Neighborhood Hits	45	Target Neighborhood Hits	700	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SREC_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.046145 (rank : 84)
Query Neighborhood Hits	45	Target Neighborhood Hits	645	Shared Neighborhood Hits	27
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

PLSL_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.011356 (rank : 88)
Query Neighborhood Hits	45	Target Neighborhood Hits	168	Shared Neighborhood Hits	2
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

SLIT3_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.057152 (rank : 69)
Query Neighborhood Hits	45	Target Neighborhood Hits	682	Shared Neighborhood Hits	24
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

HABP2_MOUSE
θ value	4.03905 (rank : 34)	NC score	0.028166 (rank : 86)
Query Neighborhood Hits	45	Target Neighborhood Hits	445	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

ISK5_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.159954 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	89	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

JAG1_MOUSE
θ value	4.03905 (rank : 36)	NC score	0.050416 (rank : 81)
Query Neighborhood Hits	45	Target Neighborhood Hits	518	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

NOTC3_MOUSE
θ value	4.03905 (rank : 37)	NC score	0.052463 (rank : 77)
Query Neighborhood Hits	45	Target Neighborhood Hits	975	Shared Neighborhood Hits	27
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SLIT1_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.051719 (rank : 78)
Query Neighborhood Hits	45	Target Neighborhood Hits	700	Shared Neighborhood Hits	24
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

G45IP_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.032733 (rank : 85)
Query Neighborhood Hits	45	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TAE8, Q8IVM3, Q8TE51, Q969P9, Q9BSM6	Gene names	GADD45GIP1, PLINP1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1 (CR6-interacting factor 1) (CRIF1) (CKII beta-associating protein) (Papillomavirus L2-interacting nuclear protein 1) (PLINP-1).

PHLPP_HUMAN
θ value	5.27518 (rank : 40)	NC score	0.014231 (rank : 87)
Query Neighborhood Hits	45	Target Neighborhood Hits	604	Shared Neighborhood Hits	11
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

RECK_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.083186 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	158	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

CFAI_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.009766 (rank : 89)
Query Neighborhood Hits	45	Target Neighborhood Hits	289	Shared Neighborhood Hits	9
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

NOTC2_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.049319 (rank : 83)
Query Neighborhood Hits	45	Target Neighborhood Hits	1113	Shared Neighborhood Hits	27
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.049447 (rank : 82)
Query Neighborhood Hits	45	Target Neighborhood Hits	1069	Shared Neighborhood Hits	26
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SLIT1_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.050599 (rank : 80)
Query Neighborhood Hits	45	Target Neighborhood Hits	715	Shared Neighborhood Hits	24
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

CRUM1_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.053256 (rank : 76)
Query Neighborhood Hits	45	Target Neighborhood Hits	457	Shared Neighborhood Hits	22
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DMP1_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.053617 (rank : 75)
Query Neighborhood Hits	45	Target Neighborhood Hits	491	Shared Neighborhood Hits	2
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

FSTL4_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.086811 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	344	Shared Neighborhood Hits	23
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL4_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.079480 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	333	Shared Neighborhood Hits	26
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL5_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.060538 (rank : 63)
Query Neighborhood Hits	45	Target Neighborhood Hits	347	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.057667 (rank : 67)
Query Neighborhood Hits	45	Target Neighborhood Hits	355	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

HG2A_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.133992 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

HG2A_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.141126 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

IBP1_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.071456 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP1_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.064570 (rank : 58)
Query Neighborhood Hits	45	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP2_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.056309 (rank : 71)
Query Neighborhood Hits	45	Target Neighborhood Hits	61	Shared Neighborhood Hits	10
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP2_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.061517 (rank : 62)
Query Neighborhood Hits	45	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP3_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.083770 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	67	Shared Neighborhood Hits	10
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP3_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.077084 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP4_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.063194 (rank : 60)
Query Neighborhood Hits	45	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.064211 (rank : 59)
Query Neighborhood Hits	45	Target Neighborhood Hits	55	Shared Neighborhood Hits	12
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP5_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.068588 (rank : 49)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.066273 (rank : 54)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP6_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.090671 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP6_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.071659 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IPK1_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.073938 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

IPK2_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.056094 (rank : 72)
Query Neighborhood Hits	45	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

IPK2_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.067046 (rank : 52)
Query Neighborhood Hits	45	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BMY7	Gene names	Spink2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 2 precursor.

ISK3_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.081395 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

ISK4_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.115859 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

ISK4_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.135430 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

ISK6_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.082267 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

ISK6_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.084140 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

ISK7_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.074594 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

ISK7_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.086734 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

KAZD1_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.068272 (rank : 50)
Query Neighborhood Hits	45	Target Neighborhood Hits	248	Shared Neighborhood Hits	22
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.060323 (rank : 64)
Query Neighborhood Hits	45	Target Neighborhood Hits	281	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

NID1_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.069418 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	329	Shared Neighborhood Hits	27
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.070066 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	335	Shared Neighborhood Hits	27
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.069258 (rank : 48)
Query Neighborhood Hits	45	Target Neighborhood Hits	456	Shared Neighborhood Hits	28
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.070096 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	338	Shared Neighborhood Hits	27
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

PTMS_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.091865 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMS_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.051606 (rank : 79)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	1
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

RECK_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.066325 (rank : 53)
Query Neighborhood Hits	45	Target Neighborhood Hits	189	Shared Neighborhood Hits	27
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

SRCH_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.059723 (rank : 65)
Query Neighborhood Hits	45	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TACD1_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.086474 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

TACD2_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.067622 (rank : 51)
Query Neighborhood Hits	45	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

THYG_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.065342 (rank : 57)
Query Neighborhood Hits	45	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

THYG_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.066152 (rank : 55)
Query Neighborhood Hits	45	Target Neighborhood Hits	161	Shared Neighborhood Hits	13
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

Hits sorted by NC score

SPRC_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.41524e-162 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
NC score	0.998490 (rank : 2)	θ value	2.85304e-163 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRL1_HUMAN
NC score	0.880255 (rank : 3)	θ value	8.77142e-88 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	231	Shared Neighborhood Hits	29
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SPRL1_MOUSE
NC score	0.817838 (rank : 4)	θ value	5.6855e-87 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	403	Shared Neighborhood Hits	30
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TICN3_MOUSE
NC score	0.493575 (rank : 5)	θ value	3.29651e-10 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	83	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_HUMAN
NC score	0.481848 (rank : 6)	θ value	1.38499e-08 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	82	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN2_MOUSE
NC score	0.477089 (rank : 7)	θ value	1.17247e-07 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_HUMAN
NC score	0.469287 (rank : 8)	θ value	7.59969e-07 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN1_MOUSE
NC score	0.458819 (rank : 9)	θ value	6.87365e-08 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	79	Shared Neighborhood Hits	25
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

FST_HUMAN
NC score	0.435027 (rank : 10)	θ value	2.21117e-06 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	129	Shared Neighborhood Hits	33
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

TICN1_HUMAN
NC score	0.434342 (rank : 11)	θ value	6.43352e-06 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

FSTL3_HUMAN
NC score	0.429025 (rank : 12)	θ value	2.44474e-05 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_MOUSE
NC score	0.425121 (rank : 13)	θ value	6.43352e-06 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	146	Shared Neighborhood Hits	34
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FSTL3_MOUSE
NC score	0.405270 (rank : 14)	θ value	0.00035302 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	152	Shared Neighborhood Hits	35
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL1_HUMAN
NC score	0.381717 (rank : 15)	θ value	0.000786445 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
NC score	0.374957 (rank : 16)	θ value	0.00134147 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	74	Shared Neighborhood Hits	27
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

SMOC2_HUMAN
NC score	0.368289 (rank : 17)	θ value	5.44631e-05 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC1_MOUSE
NC score	0.365749 (rank : 18)	θ value	9.29e-05 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

SMOC2_MOUSE
NC score	0.357769 (rank : 19)	θ value	0.000158464 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	81	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

SMOC1_HUMAN
NC score	0.357398 (rank : 20)	θ value	0.000121331 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	81	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

TEFF2_MOUSE
NC score	0.237921 (rank : 21)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	214	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEFF2_HUMAN
NC score	0.235408 (rank : 22)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	211	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

AGRIN_HUMAN
NC score	0.199180 (rank : 23)	θ value	0.000270298 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	582	Shared Neighborhood Hits	42
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ISK5_HUMAN
NC score	0.159954 (rank : 24)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	89	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

HG2A_MOUSE
NC score	0.141126 (rank : 25)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	45	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

ISK4_MOUSE
NC score	0.135430 (rank : 26)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	45	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

HG2A_HUMAN
NC score	0.133992 (rank : 27)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	45	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

ISK4_HUMAN
NC score	0.115859 (rank : 28)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	45	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

PTMS_HUMAN
NC score	0.091865 (rank : 29)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	45	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

IBP6_HUMAN
NC score	0.090671 (rank : 30)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	45	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

FSTL4_HUMAN
NC score	0.086811 (rank : 31)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	45	Target Neighborhood Hits	344	Shared Neighborhood Hits	23
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

ISK7_MOUSE
NC score	0.086734 (rank : 32)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	45	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

TACD1_HUMAN
NC score	0.086474 (rank : 33)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	45	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

ISK6_MOUSE
NC score	0.084140 (rank : 34)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	45	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

IBP3_HUMAN
NC score	0.083770 (rank : 35)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	45	Target Neighborhood Hits	67	Shared Neighborhood Hits	10
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

RECK_MOUSE
NC score	0.083186 (rank : 36)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	158	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

ISK6_HUMAN
NC score	0.082267 (rank : 37)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	45	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

ISK3_MOUSE
NC score	0.081395 (rank : 38)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	45	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

FSTL4_MOUSE
NC score	0.079480 (rank : 39)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	45	Target Neighborhood Hits	333	Shared Neighborhood Hits	26
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

IBP3_MOUSE
NC score	0.077084 (rank : 40)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	45	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

ISK7_HUMAN
NC score	0.074594 (rank : 41)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	45	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

IPK1_HUMAN
NC score	0.073938 (rank : 42)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	45	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

IBP6_MOUSE
NC score	0.071659 (rank : 43)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	45	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP1_HUMAN
NC score	0.071456 (rank : 44)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	45	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

NID2_MOUSE
NC score	0.070096 (rank : 45)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	45	Target Neighborhood Hits	338	Shared Neighborhood Hits	27
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NID1_MOUSE
NC score	0.070066 (rank : 46)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	45	Target Neighborhood Hits	335	Shared Neighborhood Hits	27
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_HUMAN
NC score	0.069418 (rank : 47)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	45	Target Neighborhood Hits	329	Shared Neighborhood Hits	27
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
NC score	0.069258 (rank : 48)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	45	Target Neighborhood Hits	456	Shared Neighborhood Hits	28
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

IBP5_HUMAN
NC score	0.068588 (rank : 49)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

KAZD1_HUMAN
NC score	0.068272 (rank : 50)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	45	Target Neighborhood Hits	248	Shared Neighborhood Hits	22
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

TACD2_HUMAN
NC score	0.067622 (rank : 51)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	45	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

IPK2_MOUSE
NC score	0.067046 (rank : 52)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	45	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BMY7	Gene names	Spink2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 2 precursor.

RECK_HUMAN
NC score	0.066325 (rank : 53)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	45	Target Neighborhood Hits	189	Shared Neighborhood Hits	27
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

IBP5_MOUSE
NC score	0.066273 (rank : 54)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

THYG_MOUSE
NC score	0.066152 (rank : 55)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	45	Target Neighborhood Hits	161	Shared Neighborhood Hits	13
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

CRUM1_MOUSE
NC score	0.066036 (rank : 56)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	444	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

THYG_HUMAN
NC score	0.065342 (rank : 57)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	45	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

IBP1_MOUSE
NC score	0.064570 (rank : 58)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	45	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP4_MOUSE
NC score	0.064211 (rank : 59)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	45	Target Neighborhood Hits	55	Shared Neighborhood Hits	12
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_HUMAN
NC score	0.063194 (rank : 60)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	45	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

NOTC3_HUMAN
NC score	0.062167 (rank : 61)	θ value	0.0113563 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	1062	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

IBP2_MOUSE
NC score	0.061517 (rank : 62)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	45	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

FSTL5_HUMAN
NC score	0.060538 (rank : 63)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	45	Target Neighborhood Hits	347	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

KAZD1_MOUSE
NC score	0.060323 (rank : 64)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	45	Target Neighborhood Hits	281	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

SRCH_HUMAN
NC score	0.059723 (rank : 65)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	45	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

NOTC1_MOUSE
NC score	0.058141 (rank : 66)	θ value	0.21417 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	916	Shared Neighborhood Hits	25
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FSTL5_MOUSE
NC score	0.057667 (rank : 67)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	45	Target Neighborhood Hits	355	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

SLIT2_HUMAN
NC score	0.057198 (rank : 68)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	708	Shared Neighborhood Hits	26
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_HUMAN
NC score	0.057152 (rank : 69)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	682	Shared Neighborhood Hits	24
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
NC score	0.056505 (rank : 70)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	700	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

IBP2_HUMAN
NC score	0.056309 (rank : 71)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	45	Target Neighborhood Hits	61	Shared Neighborhood Hits	10
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IPK2_HUMAN
NC score	0.056094 (rank : 72)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	45	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

SLIT2_MOUSE
NC score	0.056049 (rank : 73)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	684	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

NOTC1_HUMAN
NC score	0.055822 (rank : 74)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	906	Shared Neighborhood Hits	25
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DMP1_HUMAN
NC score	0.053617 (rank : 75)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	491	Shared Neighborhood Hits	2
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

CRUM1_HUMAN
NC score	0.053256 (rank : 76)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	457	Shared Neighborhood Hits	22
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

NOTC3_MOUSE
NC score	0.052463 (rank : 77)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	975	Shared Neighborhood Hits	27
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SLIT1_HUMAN
NC score	0.051719 (rank : 78)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	700	Shared Neighborhood Hits	24
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

PTMS_MOUSE
NC score	0.051606 (rank : 79)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	1
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

SLIT1_MOUSE
NC score	0.050599 (rank : 80)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	715	Shared Neighborhood Hits	24
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

JAG1_MOUSE
NC score	0.050416 (rank : 81)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	518	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

NOTC2_MOUSE
NC score	0.049447 (rank : 82)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	1069	Shared Neighborhood Hits	26
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
NC score	0.049319 (rank : 83)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	1113	Shared Neighborhood Hits	27
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SREC_HUMAN
NC score	0.046145 (rank : 84)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	645	Shared Neighborhood Hits	27
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

G45IP_HUMAN
NC score	0.032733 (rank : 85)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TAE8, Q8IVM3, Q8TE51, Q969P9, Q9BSM6	Gene names	GADD45GIP1, PLINP1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1 (CR6-interacting factor 1) (CRIF1) (CKII beta-associating protein) (Papillomavirus L2-interacting nuclear protein 1) (PLINP-1).

HABP2_MOUSE
NC score	0.028166 (rank : 86)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	445	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

PHLPP_HUMAN
NC score	0.014231 (rank : 87)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	604	Shared Neighborhood Hits	11
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PLSL_HUMAN
NC score	0.011356 (rank : 88)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	168	Shared Neighborhood Hits	2
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

CFAI_HUMAN
NC score	0.009766 (rank : 89)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	289	Shared Neighborhood Hits	9
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].