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Network neighborhood for query Sequence : THYG_MOUSE

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THYG_MOUSE
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

THYG_HUMAN
θ value	0 (rank : 1)	NC score	0.990719 (rank : 2)
Query Neighborhood Hits	161	Target Neighborhood Hits	154	Shared Neighborhood Hits	106
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

THYG_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	161
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

ACES_MOUSE
θ value	6.32992e-62 (rank : 3)	NC score	0.843846 (rank : 4)
Query Neighborhood Hits	161	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

ACES_HUMAN
θ value	1.55911e-60 (rank : 4)	NC score	0.844364 (rank : 3)
Query Neighborhood Hits	161	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

CHLE_MOUSE
θ value	2.94036e-59 (rank : 5)	NC score	0.843386 (rank : 5)
Query Neighborhood Hits	161	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

CHLE_HUMAN
θ value	1.45929e-58 (rank : 6)	NC score	0.840715 (rank : 6)
Query Neighborhood Hits	161	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P06276	Gene names	BCHE, CHE1
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

NLGN3_MOUSE
θ value	7.01481e-53 (rank : 7)	NC score	0.810189 (rank : 17)
Query Neighborhood Hits	161	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGNX_HUMAN
θ value	9.16162e-53 (rank : 8)	NC score	0.809915 (rank : 19)
Query Neighborhood Hits	161	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

NLGNY_HUMAN
θ value	9.16162e-53 (rank : 9)	NC score	0.810148 (rank : 18)
Query Neighborhood Hits	161	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

NLGN2_HUMAN
θ value	2.041e-52 (rank : 10)	NC score	0.812449 (rank : 12)
Query Neighborhood Hits	161	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGN2_MOUSE
θ value	5.93839e-52 (rank : 11)	NC score	0.812058 (rank : 13)
Query Neighborhood Hits	161	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGN3_HUMAN
θ value	2.49495e-50 (rank : 12)	NC score	0.808596 (rank : 20)
Query Neighborhood Hits	161	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

EST2_HUMAN
θ value	1.15895e-47 (rank : 13)	NC score	0.829779 (rank : 7)
Query Neighborhood Hits	161	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

CES3_MOUSE
θ value	6.35935e-46 (rank : 14)	NC score	0.813010 (rank : 11)
Query Neighborhood Hits	161	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCT4, Q91ZV9, Q924V8, Q9ULY1	Gene names	Ces3, Ces1
Domain Architecture	No domain graphic available
Description	Carboxylesterase 3 precursor (EC 3.1.1.1) (Triacylglycerol hydrolase) (TGH).

NLGN1_MOUSE
θ value	1.08474e-45 (rank : 15)	NC score	0.804528 (rank : 21)
Query Neighborhood Hits	161	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q99K10	Gene names	Nlgn1, Kiaa1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN1_HUMAN
θ value	4.122e-45 (rank : 16)	NC score	0.804342 (rank : 22)
Query Neighborhood Hits	161	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.

EST22_MOUSE
θ value	4.55743e-44 (rank : 17)	NC score	0.813374 (rank : 10)
Query Neighborhood Hits	161	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q64176	Gene names	Es22
Domain Architecture
Description	Liver carboxylesterase 22 precursor (EC 3.1.1.1) (Egasyn) (Esterase- 22) (Es-22).

EST1_HUMAN
θ value	1.01529e-43 (rank : 18)	NC score	0.811279 (rank : 15)
Query Neighborhood Hits	161	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P23141, Q00015, Q13657, Q14062, Q16737, Q16788, Q86UK2, Q96EE8, Q9UK77, Q9ULY2	Gene names	CES1, CES2, SES1
Domain Architecture
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ACAT) (Monocyte/macrophage serine esterase) (HMSE) (Serine esterase 1) (Brain carboxylesterase hBr1) (Triacylglycerol hydrolase) (TGH) (Egasyn).

CEL_MOUSE
θ value	6.58091e-43 (rank : 19)	NC score	0.826710 (rank : 8)
Query Neighborhood Hits	161	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q64285	Gene names	Cel, Lip1
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

ESTN_MOUSE
θ value	3.61106e-41 (rank : 20)	NC score	0.811455 (rank : 14)
Query Neighborhood Hits	161	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

EST1_MOUSE
θ value	1.05066e-40 (rank : 21)	NC score	0.810760 (rank : 16)
Query Neighborhood Hits	161	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

EST31_MOUSE
θ value	6.37413e-38 (rank : 22)	NC score	0.823114 (rank : 9)
Query Neighborhood Hits	161	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q63880	Gene names	Es31
Domain Architecture
Description	Liver carboxylesterase 31 precursor (EC 3.1.1.1) (ES-Male) (Esterase- 31).

CEL_HUMAN
θ value	1.85459e-37 (rank : 23)	NC score	0.623517 (rank : 23)
Query Neighborhood Hits	161	Target Neighborhood Hits	896	Shared Neighborhood Hits	32
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

NID2_HUMAN
θ value	5.99374e-20 (rank : 24)	NC score	0.200004 (rank : 46)
Query Neighborhood Hits	161	Target Neighborhood Hits	456	Shared Neighborhood Hits	79
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	6.62687e-19 (rank : 25)	NC score	0.199085 (rank : 47)
Query Neighborhood Hits	161	Target Neighborhood Hits	338	Shared Neighborhood Hits	72
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

SMOC2_HUMAN
θ value	1.09485e-13 (rank : 26)	NC score	0.351411 (rank : 25)
Query Neighborhood Hits	161	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC2_MOUSE
θ value	1.09485e-13 (rank : 27)	NC score	0.352299 (rank : 24)
Query Neighborhood Hits	161	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

SMOC1_HUMAN
θ value	2.98157e-11 (rank : 28)	NC score	0.338295 (rank : 26)
Query Neighborhood Hits	161	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC1_MOUSE
θ value	2.98157e-11 (rank : 29)	NC score	0.330585 (rank : 27)
Query Neighborhood Hits	161	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

NID1_HUMAN
θ value	1.38499e-08 (rank : 30)	NC score	0.172764 (rank : 52)
Query Neighborhood Hits	161	Target Neighborhood Hits	329	Shared Neighborhood Hits	75
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TICN3_HUMAN
θ value	1.38499e-08 (rank : 31)	NC score	0.280434 (rank : 34)
Query Neighborhood Hits	161	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_MOUSE
θ value	1.38499e-08 (rank : 32)	NC score	0.277570 (rank : 35)
Query Neighborhood Hits	161	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN1_MOUSE
θ value	3.08544e-08 (rank : 33)	NC score	0.284321 (rank : 31)
Query Neighborhood Hits	161	Target Neighborhood Hits	79	Shared Neighborhood Hits	36
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

SCUB3_HUMAN
θ value	6.87365e-08 (rank : 34)	NC score	0.105243 (rank : 56)
Query Neighborhood Hits	161	Target Neighborhood Hits	428	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TICN1_HUMAN
θ value	8.97725e-08 (rank : 35)	NC score	0.285384 (rank : 30)
Query Neighborhood Hits	161	Target Neighborhood Hits	70	Shared Neighborhood Hits	36
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

SCUB3_MOUSE
θ value	1.17247e-07 (rank : 36)	NC score	0.105436 (rank : 55)
Query Neighborhood Hits	161	Target Neighborhood Hits	442	Shared Neighborhood Hits	80
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TICN2_MOUSE
θ value	1.53129e-07 (rank : 37)	NC score	0.281854 (rank : 33)
Query Neighborhood Hits	161	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_HUMAN
θ value	1.99992e-07 (rank : 38)	NC score	0.283740 (rank : 32)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

NID1_MOUSE
θ value	2.61198e-07 (rank : 39)	NC score	0.169264 (rank : 53)
Query Neighborhood Hits	161	Target Neighborhood Hits	335	Shared Neighborhood Hits	71
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

HG2A_HUMAN
θ value	2.44474e-05 (rank : 40)	NC score	0.289598 (rank : 29)
Query Neighborhood Hits	161	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

HG2A_MOUSE
θ value	9.29e-05 (rank : 41)	NC score	0.302982 (rank : 28)
Query Neighborhood Hits	161	Target Neighborhood Hits	36	Shared Neighborhood Hits	32
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

IBP1_MOUSE
θ value	9.29e-05 (rank : 42)	NC score	0.213767 (rank : 40)
Query Neighborhood Hits	161	Target Neighborhood Hits	97	Shared Neighborhood Hits	33
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP6_HUMAN
θ value	0.000158464 (rank : 43)	NC score	0.248541 (rank : 36)
Query Neighborhood Hits	161	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP1_HUMAN
θ value	0.00035302 (rank : 44)	NC score	0.225619 (rank : 37)
Query Neighborhood Hits	161	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP5_MOUSE
θ value	0.00035302 (rank : 45)	NC score	0.207607 (rank : 42)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_HUMAN
θ value	0.000786445 (rank : 46)	NC score	0.207449 (rank : 43)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP3_HUMAN
θ value	0.00175202 (rank : 47)	NC score	0.219414 (rank : 39)
Query Neighborhood Hits	161	Target Neighborhood Hits	67	Shared Neighborhood Hits	34
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

EPHB3_HUMAN
θ value	0.00228821 (rank : 48)	NC score	0.036275 (rank : 136)
Query Neighborhood Hits	161	Target Neighborhood Hits	996	Shared Neighborhood Hits	47
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHB3_MOUSE
θ value	0.00869519 (rank : 49)	NC score	0.034509 (rank : 140)
Query Neighborhood Hits	161	Target Neighborhood Hits	996	Shared Neighborhood Hits	44
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

IBP6_MOUSE
θ value	0.00869519 (rank : 50)	NC score	0.219533 (rank : 38)
Query Neighborhood Hits	161	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

TACD1_HUMAN
θ value	0.00869519 (rank : 51)	NC score	0.193159 (rank : 48)
Query Neighborhood Hits	161	Target Neighborhood Hits	34	Shared Neighborhood Hits	32
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

IBP3_MOUSE
θ value	0.0148317 (rank : 52)	NC score	0.208775 (rank : 41)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	34
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

MEGF9_HUMAN
θ value	0.0193708 (rank : 53)	NC score	0.076525 (rank : 60)
Query Neighborhood Hits	161	Target Neighborhood Hits	557	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LTBP2_MOUSE
θ value	0.0252991 (rank : 54)	NC score	0.061338 (rank : 68)
Query Neighborhood Hits	161	Target Neighborhood Hits	617	Shared Neighborhood Hits	70
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

PKHG4_HUMAN
θ value	0.0330416 (rank : 55)	NC score	0.030390 (rank : 157)
Query Neighborhood Hits	161	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

IBP4_HUMAN
θ value	0.0431538 (rank : 56)	NC score	0.204977 (rank : 45)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	32
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_MOUSE
θ value	0.0431538 (rank : 57)	NC score	0.206249 (rank : 44)
Query Neighborhood Hits	161	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

CREL1_MOUSE
θ value	0.0563607 (rank : 58)	NC score	0.080653 (rank : 59)
Query Neighborhood Hits	161	Target Neighborhood Hits	524	Shared Neighborhood Hits	57
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

STAB2_HUMAN
θ value	0.0563607 (rank : 59)	NC score	0.068565 (rank : 62)
Query Neighborhood Hits	161	Target Neighborhood Hits	534	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
θ value	0.0736092 (rank : 60)	NC score	0.075581 (rank : 61)
Query Neighborhood Hits	161	Target Neighborhood Hits	528	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

EPHB2_HUMAN
θ value	0.0961366 (rank : 61)	NC score	0.032955 (rank : 145)
Query Neighborhood Hits	161	Target Neighborhood Hits	983	Shared Neighborhood Hits	41
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	0.0961366 (rank : 62)	NC score	0.032953 (rank : 146)
Query Neighborhood Hits	161	Target Neighborhood Hits	982	Shared Neighborhood Hits	41
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB6_HUMAN
θ value	0.0961366 (rank : 63)	NC score	0.041549 (rank : 127)
Query Neighborhood Hits	161	Target Neighborhood Hits	912	Shared Neighborhood Hits	56
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

TACD2_HUMAN
θ value	0.0961366 (rank : 64)	NC score	0.156324 (rank : 54)
Query Neighborhood Hits	161	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

CREL1_HUMAN
θ value	0.125558 (rank : 65)	NC score	0.085896 (rank : 58)
Query Neighborhood Hits	161	Target Neighborhood Hits	441	Shared Neighborhood Hits	57
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EPHA2_MOUSE
θ value	0.125558 (rank : 66)	NC score	0.030967 (rank : 153)
Query Neighborhood Hits	161	Target Neighborhood Hits	1020	Shared Neighborhood Hits	52
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHB4_HUMAN
θ value	0.125558 (rank : 67)	NC score	0.035556 (rank : 137)
Query Neighborhood Hits	161	Target Neighborhood Hits	1056	Shared Neighborhood Hits	65
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

IBP2_MOUSE
θ value	0.125558 (rank : 68)	NC score	0.190387 (rank : 49)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	32
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

FRAS1_MOUSE
θ value	0.163984 (rank : 69)	NC score	0.039524 (rank : 131)
Query Neighborhood Hits	161	Target Neighborhood Hits	747	Shared Neighborhood Hits	67
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

EPHB4_MOUSE
θ value	0.21417 (rank : 70)	NC score	0.033182 (rank : 142)
Query Neighborhood Hits	161	Target Neighborhood Hits	1013	Shared Neighborhood Hits	53
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

RGS3_HUMAN
θ value	0.21417 (rank : 71)	NC score	0.009688 (rank : 182)
Query Neighborhood Hits	161	Target Neighborhood Hits	1375	Shared Neighborhood Hits	11
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

IBP2_HUMAN
θ value	0.279714 (rank : 72)	NC score	0.179774 (rank : 51)
Query Neighborhood Hits	161	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

TNR9_HUMAN
θ value	0.279714 (rank : 73)	NC score	0.067512 (rank : 63)
Query Neighborhood Hits	161	Target Neighborhood Hits	166	Shared Neighborhood Hits	51
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

EPHA4_MOUSE
θ value	0.365318 (rank : 74)	NC score	0.030791 (rank : 155)
Query Neighborhood Hits	161	Target Neighborhood Hits	982	Shared Neighborhood Hits	43
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHB6_MOUSE
θ value	0.365318 (rank : 75)	NC score	0.039121 (rank : 132)
Query Neighborhood Hits	161	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

WBP1_HUMAN
θ value	0.365318 (rank : 76)	NC score	0.030914 (rank : 154)
Query Neighborhood Hits	161	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q96G27, O95637	Gene names	WBP1
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 1 (WBP-1).

WIF1_MOUSE
θ value	0.365318 (rank : 77)	NC score	0.047516 (rank : 114)
Query Neighborhood Hits	161	Target Neighborhood Hits	393	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

EPHA6_HUMAN
θ value	0.47712 (rank : 78)	NC score	0.032402 (rank : 149)
Query Neighborhood Hits	161	Target Neighborhood Hits	959	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

MEGF9_MOUSE
θ value	0.47712 (rank : 79)	NC score	0.064383 (rank : 66)
Query Neighborhood Hits	161	Target Neighborhood Hits	896	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

TNR16_HUMAN
θ value	0.47712 (rank : 80)	NC score	0.051787 (rank : 91)
Query Neighborhood Hits	161	Target Neighborhood Hits	183	Shared Neighborhood Hits	50
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR21_MOUSE
θ value	0.47712 (rank : 81)	NC score	0.042559 (rank : 122)
Query Neighborhood Hits	161	Target Neighborhood Hits	108	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

CJ047_MOUSE
θ value	0.62314 (rank : 82)	NC score	0.027839 (rank : 162)
Query Neighborhood Hits	161	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

EPHA6_MOUSE
θ value	0.62314 (rank : 83)	NC score	0.032853 (rank : 147)
Query Neighborhood Hits	161	Target Neighborhood Hits	946	Shared Neighborhood Hits	48
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

NLTP_HUMAN
θ value	0.813845 (rank : 84)	NC score	0.027102 (rank : 164)
Query Neighborhood Hits	161	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	P22307, Q15432, Q16622, Q99430	Gene names	SCP2
Domain Architecture
Description	Nonspecific lipid-transfer protein (EC 2.3.1.176) (Propanoyl-CoA C- acyltransferase) (NSL-TP) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) (SCP-chi) (SCPX).

NLTP_MOUSE
θ value	0.813845 (rank : 85)	NC score	0.026957 (rank : 166)
Query Neighborhood Hits	161	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P32020, Q9DBM7	Gene names	Scp2, Scp-2
Domain Architecture
Description	Nonspecific lipid-transfer protein (EC 2.3.1.176) (Propanoyl-CoA C- acyltransferase) (NSL-TP) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) (SCP-chi) (SCPX).

TNR21_HUMAN
θ value	0.813845 (rank : 86)	NC score	0.040427 (rank : 130)
Query Neighborhood Hits	161	Target Neighborhood Hits	90	Shared Neighborhood Hits	29
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

AASS_HUMAN
θ value	1.06291 (rank : 87)	NC score	0.020346 (rank : 171)
Query Neighborhood Hits	161	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UDR5, O95462	Gene names	AASS
Domain Architecture
Description	Alpha-aminoadipic semialdehyde synthase, mitochondrial precursor (LKR/SDH) [Includes: Lysine ketoglutarate reductase (EC 1.5.1.8) (LOR) (LKR); Saccharopine dehydrogenase (EC 1.5.1.9) (SDH)].

ATRN_MOUSE
θ value	1.06291 (rank : 88)	NC score	0.037562 (rank : 135)
Query Neighborhood Hits	161	Target Neighborhood Hits	519	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

FRAS1_HUMAN
θ value	1.06291 (rank : 89)	NC score	0.040912 (rank : 128)
Query Neighborhood Hits	161	Target Neighborhood Hits	759	Shared Neighborhood Hits	68
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FUT1_MOUSE
θ value	1.06291 (rank : 90)	NC score	0.016497 (rank : 173)
Query Neighborhood Hits	161	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	O09160	Gene names	Fut1
Domain Architecture
Description	Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (GDP-L- fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1) (Alpha(1,2)FT 1) (Fucosyltransferase 1).

LAMC2_HUMAN
θ value	1.06291 (rank : 91)	NC score	0.054407 (rank : 81)
Query Neighborhood Hits	161	Target Neighborhood Hits	715	Shared Neighborhood Hits	78
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	1.06291 (rank : 92)	NC score	0.059503 (rank : 72)
Query Neighborhood Hits	161	Target Neighborhood Hits	614	Shared Neighborhood Hits	77
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LTBP3_MOUSE
θ value	1.06291 (rank : 93)	NC score	0.055247 (rank : 79)
Query Neighborhood Hits	161	Target Neighborhood Hits	475	Shared Neighborhood Hits	62
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

ATRN_HUMAN
θ value	1.38821 (rank : 94)	NC score	0.038002 (rank : 134)
Query Neighborhood Hits	161	Target Neighborhood Hits	525	Shared Neighborhood Hits	53
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

PCSK5_HUMAN
θ value	1.38821 (rank : 95)	NC score	0.042786 (rank : 121)
Query Neighborhood Hits	161	Target Neighborhood Hits	291	Shared Neighborhood Hits	61
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

TNR9_MOUSE
θ value	1.38821 (rank : 96)	NC score	0.052077 (rank : 89)
Query Neighborhood Hits	161	Target Neighborhood Hits	137	Shared Neighborhood Hits	47
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

EPHA4_HUMAN
θ value	1.81305 (rank : 97)	NC score	0.029116 (rank : 161)
Query Neighborhood Hits	161	Target Neighborhood Hits	975	Shared Neighborhood Hits	41
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

LAMA3_HUMAN
θ value	1.81305 (rank : 98)	NC score	0.038088 (rank : 133)
Query Neighborhood Hits	161	Target Neighborhood Hits	760	Shared Neighborhood Hits	68
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

SREC_HUMAN
θ value	1.81305 (rank : 99)	NC score	0.049340 (rank : 113)
Query Neighborhood Hits	161	Target Neighborhood Hits	645	Shared Neighborhood Hits	69
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

TEP1_HUMAN
θ value	1.81305 (rank : 100)	NC score	0.004658 (rank : 191)
Query Neighborhood Hits	161	Target Neighborhood Hits	371	Shared Neighborhood Hits	2
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

CSTN2_HUMAN
θ value	2.36792 (rank : 101)	NC score	0.007137 (rank : 187)
Query Neighborhood Hits	161	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4D0, Q9BSS0	Gene names	CLSTN2, CS2
Domain Architecture
Description	Calsyntenin-2 precursor.

EPHA1_HUMAN
θ value	2.36792 (rank : 102)	NC score	0.029742 (rank : 159)
Query Neighborhood Hits	161	Target Neighborhood Hits	997	Shared Neighborhood Hits	53
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHAA_HUMAN
θ value	2.36792 (rank : 103)	NC score	0.033178 (rank : 143)
Query Neighborhood Hits	161	Target Neighborhood Hits	960	Shared Neighborhood Hits	46
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

LAMA1_MOUSE
θ value	2.36792 (rank : 104)	NC score	0.047143 (rank : 115)
Query Neighborhood Hits	161	Target Neighborhood Hits	838	Shared Neighborhood Hits	77
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA3_MOUSE
θ value	2.36792 (rank : 105)	NC score	0.043934 (rank : 117)
Query Neighborhood Hits	161	Target Neighborhood Hits	859	Shared Neighborhood Hits	73
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

NOTC3_MOUSE
θ value	2.36792 (rank : 106)	NC score	0.041629 (rank : 126)
Query Neighborhood Hits	161	Target Neighborhood Hits	975	Shared Neighborhood Hits	63
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TENR_HUMAN
θ value	2.36792 (rank : 107)	NC score	0.031018 (rank : 152)
Query Neighborhood Hits	161	Target Neighborhood Hits	526	Shared Neighborhood Hits	64
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TNR16_MOUSE
θ value	2.36792 (rank : 108)	NC score	0.049885 (rank : 112)
Query Neighborhood Hits	161	Target Neighborhood Hits	178	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

EPHA7_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.032964 (rank : 144)
Query Neighborhood Hits	161	Target Neighborhood Hits	1053	Shared Neighborhood Hits	61
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

KR261_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.013561 (rank : 177)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

MEGF6_HUMAN
θ value	3.0926 (rank : 111)	NC score	0.061171 (rank : 69)
Query Neighborhood Hits	161	Target Neighborhood Hits	671	Shared Neighborhood Hits	79
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF8_HUMAN
θ value	3.0926 (rank : 112)	NC score	0.062155 (rank : 67)
Query Neighborhood Hits	161	Target Neighborhood Hits	528	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NOTC3_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.044913 (rank : 116)
Query Neighborhood Hits	161	Target Neighborhood Hits	1062	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PCSK5_MOUSE
θ value	3.0926 (rank : 114)	NC score	0.050252 (rank : 108)
Query Neighborhood Hits	161	Target Neighborhood Hits	613	Shared Neighborhood Hits	77
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TR10B_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.025891 (rank : 169)
Query Neighborhood Hits	161	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR19L_HUMAN
θ value	3.0926 (rank : 116)	NC score	0.030657 (rank : 156)
Query Neighborhood Hits	161	Target Neighborhood Hits	99	Shared Neighborhood Hits	30
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

USH2A_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.042919 (rank : 120)
Query Neighborhood Hits	161	Target Neighborhood Hits	600	Shared Neighborhood Hits	80
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

WIF1_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.042282 (rank : 124)
Query Neighborhood Hits	161	Target Neighborhood Hits	392	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

APBB2_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.012860 (rank : 178)
Query Neighborhood Hits	161	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB2_MOUSE
θ value	4.03905 (rank : 120)	NC score	0.011557 (rank : 179)
Query Neighborhood Hits	161	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

EPHA1_MOUSE
θ value	4.03905 (rank : 121)	NC score	0.029313 (rank : 160)
Query Neighborhood Hits	161	Target Neighborhood Hits	958	Shared Neighborhood Hits	53
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

FBLN1_MOUSE
θ value	4.03905 (rank : 122)	NC score	0.057683 (rank : 76)
Query Neighborhood Hits	161	Target Neighborhood Hits	329	Shared Neighborhood Hits	50
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

KR102_HUMAN
θ value	4.03905 (rank : 123)	NC score	0.025992 (rank : 168)
Query Neighborhood Hits	161	Target Neighborhood Hits	264	Shared Neighborhood Hits	36
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

MKS3_MOUSE
θ value	4.03905 (rank : 124)	NC score	0.026275 (rank : 167)
Query Neighborhood Hits	161	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

TENR_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.030295 (rank : 158)
Query Neighborhood Hits	161	Target Neighborhood Hits	531	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

ARI4A_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.006795 (rank : 189)
Query Neighborhood Hits	161	Target Neighborhood Hits	434	Shared Neighborhood Hits	3
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CASR_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.007091 (rank : 188)
Query Neighborhood Hits	161	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

LAMA1_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.043833 (rank : 118)
Query Neighborhood Hits	161	Target Neighborhood Hits	804	Shared Neighborhood Hits	78
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.040553 (rank : 129)
Query Neighborhood Hits	161	Target Neighborhood Hits	1092	Shared Neighborhood Hits	78
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

MEGF8_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.060768 (rank : 71)
Query Neighborhood Hits	161	Target Neighborhood Hits	520	Shared Neighborhood Hits	58
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NDUB9_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.014169 (rank : 175)
Query Neighborhood Hits	161	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6M9, Q9UQE8	Gene names	NDUFB9, UQOR22
Domain Architecture
Description	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase B22 subunit) (Complex I-B22) (CI-B22).

TNR5_MOUSE
θ value	5.27518 (rank : 132)	NC score	0.031945 (rank : 151)
Query Neighborhood Hits	161	Target Neighborhood Hits	131	Shared Neighborhood Hits	35
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TR10C_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.032334 (rank : 150)
Query Neighborhood Hits	161	Target Neighborhood Hits	105	Shared Neighborhood Hits	29
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

ZAN_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.043050 (rank : 119)
Query Neighborhood Hits	161	Target Neighborhood Hits	808	Shared Neighborhood Hits	69
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CELR1_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.015192 (rank : 174)
Query Neighborhood Hits	161	Target Neighborhood Hits	613	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

EPHA2_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.027020 (rank : 165)
Query Neighborhood Hits	161	Target Neighborhood Hits	1021	Shared Neighborhood Hits	48
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

GAK8_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.003838 (rank : 192)
Query Neighborhood Hits	161	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LRP12_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.009461 (rank : 183)
Query Neighborhood Hits	161	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

MKS3_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.033197 (rank : 141)
Query Neighborhood Hits	161	Target Neighborhood Hits	79	Shared Neighborhood Hits	35
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

RABX5_HUMAN
θ value	6.88961 (rank : 140)	NC score	0.008273 (rank : 186)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

RSPO1_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.017820 (rank : 172)
Query Neighborhood Hits	161	Target Neighborhood Hits	101	Shared Neighborhood Hits	21
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

SNX6_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.009045 (rank : 184)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNH7, Q9Y449	Gene names	SNX6
Domain Architecture
Description	Sorting nexin-6 (TRAF4-associated factor 2).

SNX6_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.009036 (rank : 185)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P8X1	Gene names	Snx6
Domain Architecture	No domain graphic available
Description	Sorting nexin-6.

TNR3_MOUSE
θ value	6.88961 (rank : 144)	NC score	0.034874 (rank : 138)
Query Neighborhood Hits	161	Target Neighborhood Hits	113	Shared Neighborhood Hits	38
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

AN32A_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.002572 (rank : 193)
Query Neighborhood Hits	161	Target Neighborhood Hits	234	Shared Neighborhood Hits	2
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

ANR26_HUMAN
θ value	8.99809 (rank : 146)	NC score	-0.004241 (rank : 197)
Query Neighborhood Hits	161	Target Neighborhood Hits	1614	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CRIS1_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.005049 (rank : 190)
Query Neighborhood Hits	161	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q03401	Gene names	Crisp1, Aeg-1, Aeg1
Domain Architecture
Description	Cysteine-rich secretory protein 1 precursor (CRISP-1) (Acidic epididymal glycoprotein 1) (Sperm-coating glycoprotein 1) (SCP 1).

DIAP2_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.011052 (rank : 180)
Query Neighborhood Hits	161	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

DLL1_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.042064 (rank : 125)
Query Neighborhood Hits	161	Target Neighborhood Hits	455	Shared Neighborhood Hits	57
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

EPHB1_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.027271 (rank : 163)
Query Neighborhood Hits	161	Target Neighborhood Hits	988	Shared Neighborhood Hits	48
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

FBN2_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.051230 (rank : 97)
Query Neighborhood Hits	161	Target Neighborhood Hits	560	Shared Neighborhood Hits	71
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

LAMA2_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.034585 (rank : 139)
Query Neighborhood Hits	161	Target Neighborhood Hits	1198	Shared Neighborhood Hits	75
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC3_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.042384 (rank : 123)
Query Neighborhood Hits	161	Target Neighborhood Hits	588	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LTBP2_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.055116 (rank : 80)
Query Neighborhood Hits	161	Target Neighborhood Hits	552	Shared Neighborhood Hits	70
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MMP17_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.001133 (rank : 194)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

PCDG4_HUMAN
θ value	8.99809 (rank : 156)	NC score	-0.000202 (rank : 195)
Query Neighborhood Hits	161	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5G9, Q9Y5D3	Gene names	PCDHGA4
Domain Architecture
Description	Protocadherin gamma A4 precursor (PCDH-gamma-A4).

PCDG5_HUMAN
θ value	8.99809 (rank : 157)	NC score	-0.000218 (rank : 196)
Query Neighborhood Hits	161	Target Neighborhood Hits	159	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5G8, Q9Y5D2	Gene names	PCDHGA5
Domain Architecture
Description	Protocadherin gamma A5 precursor (PCDH-gamma-A5).

PUS7_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.010666 (rank : 181)
Query Neighborhood Hits	161	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PZ0, Q75MG4, Q9NX19	Gene names	PUS7, KIAA1897
Domain Architecture
Description	Pseudouridylate synthase 7 homolog (EC 5.4.99.-).

SSPO_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.022168 (rank : 170)
Query Neighborhood Hits	161	Target Neighborhood Hits	800	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TNR25_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.032779 (rank : 148)
Query Neighborhood Hits	161	Target Neighborhood Hits	172	Shared Neighborhood Hits	48
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR27_MOUSE
θ value	8.99809 (rank : 161)	NC score	0.013917 (rank : 176)
Query Neighborhood Hits	161	Target Neighborhood Hits	61	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

AAAD_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.180217 (rank : 50)
Query Neighborhood Hits	161	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P22760, Q8N1A9	Gene names	AADAC, DAC
Domain Architecture
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

AAAD_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.100211 (rank : 57)
Query Neighborhood Hits	161	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

AGRIN_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.059318 (rank : 74)
Query Neighborhood Hits	161	Target Neighborhood Hits	582	Shared Neighborhood Hits	69
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

C1QR1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.052054 (rank : 90)
Query Neighborhood Hits	161	Target Neighborhood Hits	493	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.051457 (rank : 95)
Query Neighborhood Hits	161	Target Neighborhood Hits	342	Shared Neighborhood Hits	47
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

EGF_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.053505 (rank : 83)
Query Neighborhood Hits	161	Target Neighborhood Hits	343	Shared Neighborhood Hits	44
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.053846 (rank : 82)
Query Neighborhood Hits	161	Target Neighborhood Hits	358	Shared Neighborhood Hits	47
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

FBLN1_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.057196 (rank : 77)
Query Neighborhood Hits	161	Target Neighborhood Hits	324	Shared Neighborhood Hits	49
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.051660 (rank : 92)
Query Neighborhood Hits	161	Target Neighborhood Hits	392	Shared Neighborhood Hits	51
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.050902 (rank : 100)
Query Neighborhood Hits	161	Target Neighborhood Hits	505	Shared Neighborhood Hits	52
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.051382 (rank : 96)
Query Neighborhood Hits	161	Target Neighborhood Hits	293	Shared Neighborhood Hits	46
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.050757 (rank : 102)
Query Neighborhood Hits	161	Target Neighborhood Hits	279	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.050214 (rank : 109)
Query Neighborhood Hits	161	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN5_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.050498 (rank : 103)
Query Neighborhood Hits	161	Target Neighborhood Hits	329	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.050768 (rank : 101)
Query Neighborhood Hits	161	Target Neighborhood Hits	317	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.050293 (rank : 106)
Query Neighborhood Hits	161	Target Neighborhood Hits	557	Shared Neighborhood Hits	69
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.050139 (rank : 111)
Query Neighborhood Hits	161	Target Neighborhood Hits	549	Shared Neighborhood Hits	67
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.051220 (rank : 98)
Query Neighborhood Hits	161	Target Neighborhood Hits	543	Shared Neighborhood Hits	71
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FST_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.050470 (rank : 104)
Query Neighborhood Hits	161	Target Neighborhood Hits	129	Shared Neighborhood Hits	21
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.050319 (rank : 105)
Query Neighborhood Hits	161	Target Neighborhood Hits	146	Shared Neighborhood Hits	26
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

LTBP3_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.050978 (rank : 99)
Query Neighborhood Hits	161	Target Neighborhood Hits	502	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.052745 (rank : 86)
Query Neighborhood Hits	161	Target Neighborhood Hits	607	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

NELL1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.052383 (rank : 88)
Query Neighborhood Hits	161	Target Neighborhood Hits	451	Shared Neighborhood Hits	49
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.051600 (rank : 93)
Query Neighborhood Hits	161	Target Neighborhood Hits	449	Shared Neighborhood Hits	53
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.051556 (rank : 94)
Query Neighborhood Hits	161	Target Neighborhood Hits	436	Shared Neighborhood Hits	53
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

SMR3B_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.058997 (rank : 75)
Query Neighborhood Hits	161	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

SPRC_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.066152 (rank : 64)
Query Neighborhood Hits	161	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.064825 (rank : 65)
Query Neighborhood Hits	161	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRL1_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.055375 (rank : 78)
Query Neighborhood Hits	161	Target Neighborhood Hits	231	Shared Neighborhood Hits	12
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SPRL1_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.050190 (rank : 110)
Query Neighborhood Hits	161	Target Neighborhood Hits	403	Shared Neighborhood Hits	14
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

STAB1_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.060917 (rank : 70)
Query Neighborhood Hits	161	Target Neighborhood Hits	546	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.059483 (rank : 73)
Query Neighborhood Hits	161	Target Neighborhood Hits	566	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TRBM_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.050284 (rank : 107)
Query Neighborhood Hits	161	Target Neighborhood Hits	339	Shared Neighborhood Hits	46
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.052903 (rank : 84)
Query Neighborhood Hits	161	Target Neighborhood Hits	361	Shared Neighborhood Hits	52
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

UROM_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.052557 (rank : 87)
Query Neighborhood Hits	161	Target Neighborhood Hits	284	Shared Neighborhood Hits	40
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.052879 (rank : 85)
Query Neighborhood Hits	161	Target Neighborhood Hits	276	Shared Neighborhood Hits	46
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

Hits sorted by NC score

THYG_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	161
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

THYG_HUMAN
NC score	0.990719 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	161	Target Neighborhood Hits	154	Shared Neighborhood Hits	106
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

ACES_HUMAN
NC score	0.844364 (rank : 3)	θ value	1.55911e-60 (rank : 4)
Query Neighborhood Hits	161	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

ACES_MOUSE
NC score	0.843846 (rank : 4)	θ value	6.32992e-62 (rank : 3)
Query Neighborhood Hits	161	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

CHLE_MOUSE
NC score	0.843386 (rank : 5)	θ value	2.94036e-59 (rank : 5)
Query Neighborhood Hits	161	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

CHLE_HUMAN
NC score	0.840715 (rank : 6)	θ value	1.45929e-58 (rank : 6)
Query Neighborhood Hits	161	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P06276	Gene names	BCHE, CHE1
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

EST2_HUMAN
NC score	0.829779 (rank : 7)	θ value	1.15895e-47 (rank : 13)
Query Neighborhood Hits	161	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

CEL_MOUSE
NC score	0.826710 (rank : 8)	θ value	6.58091e-43 (rank : 19)
Query Neighborhood Hits	161	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q64285	Gene names	Cel, Lip1
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EST31_MOUSE
NC score	0.823114 (rank : 9)	θ value	6.37413e-38 (rank : 22)
Query Neighborhood Hits	161	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q63880	Gene names	Es31
Domain Architecture
Description	Liver carboxylesterase 31 precursor (EC 3.1.1.1) (ES-Male) (Esterase- 31).

EST22_MOUSE
NC score	0.813374 (rank : 10)	θ value	4.55743e-44 (rank : 17)
Query Neighborhood Hits	161	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q64176	Gene names	Es22
Domain Architecture
Description	Liver carboxylesterase 22 precursor (EC 3.1.1.1) (Egasyn) (Esterase- 22) (Es-22).

CES3_MOUSE
NC score	0.813010 (rank : 11)	θ value	6.35935e-46 (rank : 14)
Query Neighborhood Hits	161	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCT4, Q91ZV9, Q924V8, Q9ULY1	Gene names	Ces3, Ces1
Domain Architecture	No domain graphic available
Description	Carboxylesterase 3 precursor (EC 3.1.1.1) (Triacylglycerol hydrolase) (TGH).

NLGN2_HUMAN
NC score	0.812449 (rank : 12)	θ value	2.041e-52 (rank : 10)
Query Neighborhood Hits	161	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGN2_MOUSE
NC score	0.812058 (rank : 13)	θ value	5.93839e-52 (rank : 11)
Query Neighborhood Hits	161	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

ESTN_MOUSE
NC score	0.811455 (rank : 14)	θ value	3.61106e-41 (rank : 20)
Query Neighborhood Hits	161	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

EST1_HUMAN
NC score	0.811279 (rank : 15)	θ value	1.01529e-43 (rank : 18)
Query Neighborhood Hits	161	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P23141, Q00015, Q13657, Q14062, Q16737, Q16788, Q86UK2, Q96EE8, Q9UK77, Q9ULY2	Gene names	CES1, CES2, SES1
Domain Architecture
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ACAT) (Monocyte/macrophage serine esterase) (HMSE) (Serine esterase 1) (Brain carboxylesterase hBr1) (Triacylglycerol hydrolase) (TGH) (Egasyn).

EST1_MOUSE
NC score	0.810760 (rank : 16)	θ value	1.05066e-40 (rank : 21)
Query Neighborhood Hits	161	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

NLGN3_MOUSE
NC score	0.810189 (rank : 17)	θ value	7.01481e-53 (rank : 7)
Query Neighborhood Hits	161	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGNY_HUMAN
NC score	0.810148 (rank : 18)	θ value	9.16162e-53 (rank : 9)
Query Neighborhood Hits	161	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

NLGNX_HUMAN
NC score	0.809915 (rank : 19)	θ value	9.16162e-53 (rank : 8)
Query Neighborhood Hits	161	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

NLGN3_HUMAN
NC score	0.808596 (rank : 20)	θ value	2.49495e-50 (rank : 12)
Query Neighborhood Hits	161	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGN1_MOUSE
NC score	0.804528 (rank : 21)	θ value	1.08474e-45 (rank : 15)
Query Neighborhood Hits	161	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q99K10	Gene names	Nlgn1, Kiaa1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN1_HUMAN
NC score	0.804342 (rank : 22)	θ value	4.122e-45 (rank : 16)
Query Neighborhood Hits	161	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.

CEL_HUMAN
NC score	0.623517 (rank : 23)	θ value	1.85459e-37 (rank : 23)
Query Neighborhood Hits	161	Target Neighborhood Hits	896	Shared Neighborhood Hits	32
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

SMOC2_MOUSE
NC score	0.352299 (rank : 24)	θ value	1.09485e-13 (rank : 27)
Query Neighborhood Hits	161	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

SMOC2_HUMAN
NC score	0.351411 (rank : 25)	θ value	1.09485e-13 (rank : 26)
Query Neighborhood Hits	161	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC1_HUMAN
NC score	0.338295 (rank : 26)	θ value	2.98157e-11 (rank : 28)
Query Neighborhood Hits	161	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC1_MOUSE
NC score	0.330585 (rank : 27)	θ value	2.98157e-11 (rank : 29)
Query Neighborhood Hits	161	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

HG2A_MOUSE
NC score	0.302982 (rank : 28)	θ value	9.29e-05 (rank : 41)
Query Neighborhood Hits	161	Target Neighborhood Hits	36	Shared Neighborhood Hits	32
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

HG2A_HUMAN
NC score	0.289598 (rank : 29)	θ value	2.44474e-05 (rank : 40)
Query Neighborhood Hits	161	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

TICN1_HUMAN
NC score	0.285384 (rank : 30)	θ value	8.97725e-08 (rank : 35)
Query Neighborhood Hits	161	Target Neighborhood Hits	70	Shared Neighborhood Hits	36
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_MOUSE
NC score	0.284321 (rank : 31)	θ value	3.08544e-08 (rank : 33)
Query Neighborhood Hits	161	Target Neighborhood Hits	79	Shared Neighborhood Hits	36
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN2_HUMAN
NC score	0.283740 (rank : 32)	θ value	1.99992e-07 (rank : 38)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_MOUSE
NC score	0.281854 (rank : 33)	θ value	1.53129e-07 (rank : 37)
Query Neighborhood Hits	161	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN3_HUMAN
NC score	0.280434 (rank : 34)	θ value	1.38499e-08 (rank : 31)
Query Neighborhood Hits	161	Target Neighborhood Hits	82	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_MOUSE
NC score	0.277570 (rank : 35)	θ value	1.38499e-08 (rank : 32)
Query Neighborhood Hits	161	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

IBP6_HUMAN
NC score	0.248541 (rank : 36)	θ value	0.000158464 (rank : 43)
Query Neighborhood Hits	161	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP1_HUMAN
NC score	0.225619 (rank : 37)	θ value	0.00035302 (rank : 44)
Query Neighborhood Hits	161	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP6_MOUSE
NC score	0.219533 (rank : 38)	θ value	0.00869519 (rank : 50)
Query Neighborhood Hits	161	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP3_HUMAN
NC score	0.219414 (rank : 39)	θ value	0.00175202 (rank : 47)
Query Neighborhood Hits	161	Target Neighborhood Hits	67	Shared Neighborhood Hits	34
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP1_MOUSE
NC score	0.213767 (rank : 40)	θ value	9.29e-05 (rank : 42)
Query Neighborhood Hits	161	Target Neighborhood Hits	97	Shared Neighborhood Hits	33
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP3_MOUSE
NC score	0.208775 (rank : 41)	θ value	0.0148317 (rank : 52)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	34
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP5_MOUSE
NC score	0.207607 (rank : 42)	θ value	0.00035302 (rank : 45)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_HUMAN
NC score	0.207449 (rank : 43)	θ value	0.000786445 (rank : 46)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP4_MOUSE
NC score	0.206249 (rank : 44)	θ value	0.0431538 (rank : 57)
Query Neighborhood Hits	161	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_HUMAN
NC score	0.204977 (rank : 45)	θ value	0.0431538 (rank : 56)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	32
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

NID2_HUMAN
NC score	0.200004 (rank : 46)	θ value	5.99374e-20 (rank : 24)
Query Neighborhood Hits	161	Target Neighborhood Hits	456	Shared Neighborhood Hits	79
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
NC score	0.199085 (rank : 47)	θ value	6.62687e-19 (rank : 25)
Query Neighborhood Hits	161	Target Neighborhood Hits	338	Shared Neighborhood Hits	72
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

TACD1_HUMAN
NC score	0.193159 (rank : 48)	θ value	0.00869519 (rank : 51)
Query Neighborhood Hits	161	Target Neighborhood Hits	34	Shared Neighborhood Hits	32
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

IBP2_MOUSE
NC score	0.190387 (rank : 49)	θ value	0.125558 (rank : 68)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	32
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

AAAD_HUMAN
NC score	0.180217 (rank : 50)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	161	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P22760, Q8N1A9	Gene names	AADAC, DAC
Domain Architecture
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

IBP2_HUMAN
NC score	0.179774 (rank : 51)	θ value	0.279714 (rank : 72)
Query Neighborhood Hits	161	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

NID1_HUMAN
NC score	0.172764 (rank : 52)	θ value	1.38499e-08 (rank : 30)
Query Neighborhood Hits	161	Target Neighborhood Hits	329	Shared Neighborhood Hits	75
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
NC score	0.169264 (rank : 53)	θ value	2.61198e-07 (rank : 39)
Query Neighborhood Hits	161	Target Neighborhood Hits	335	Shared Neighborhood Hits	71
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TACD2_HUMAN
NC score	0.156324 (rank : 54)	θ value	0.0961366 (rank : 64)
Query Neighborhood Hits	161	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

SCUB3_MOUSE
NC score	0.105436 (rank : 55)	θ value	1.17247e-07 (rank : 36)
Query Neighborhood Hits	161	Target Neighborhood Hits	442	Shared Neighborhood Hits	80
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.105243 (rank : 56)	θ value	6.87365e-08 (rank : 34)
Query Neighborhood Hits	161	Target Neighborhood Hits	428	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

AAAD_MOUSE
NC score	0.100211 (rank : 57)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	161	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

CREL1_HUMAN
NC score	0.085896 (rank : 58)	θ value	0.125558 (rank : 65)
Query Neighborhood Hits	161	Target Neighborhood Hits	441	Shared Neighborhood Hits	57
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
NC score	0.080653 (rank : 59)	θ value	0.0563607 (rank : 58)
Query Neighborhood Hits	161	Target Neighborhood Hits	524	Shared Neighborhood Hits	57
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

MEGF9_HUMAN
NC score	0.076525 (rank : 60)	θ value	0.0193708 (rank : 53)
Query Neighborhood Hits	161	Target Neighborhood Hits	557	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

STAB2_MOUSE
NC score	0.075581 (rank : 61)	θ value	0.0736092 (rank : 60)
Query Neighborhood Hits	161	Target Neighborhood Hits	528	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

STAB2_HUMAN
NC score	0.068565 (rank : 62)	θ value	0.0563607 (rank : 59)
Query Neighborhood Hits	161	Target Neighborhood Hits	534	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

TNR9_HUMAN
NC score	0.067512 (rank : 63)	θ value	0.279714 (rank : 73)
Query Neighborhood Hits	161	Target Neighborhood Hits	166	Shared Neighborhood Hits	51
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

SPRC_HUMAN
NC score	0.066152 (rank : 64)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	161	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
NC score	0.064825 (rank : 65)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	161	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

MEGF9_MOUSE
NC score	0.064383 (rank : 66)	θ value	0.47712 (rank : 79)
Query Neighborhood Hits	161	Target Neighborhood Hits	896	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF8_HUMAN
NC score	0.062155 (rank : 67)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	161	Target Neighborhood Hits	528	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LTBP2_MOUSE
NC score	0.061338 (rank : 68)	θ value	0.0252991 (rank : 54)
Query Neighborhood Hits	161	Target Neighborhood Hits	617	Shared Neighborhood Hits	70
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MEGF6_HUMAN
NC score	0.061171 (rank : 69)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	161	Target Neighborhood Hits	671	Shared Neighborhood Hits	79
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

STAB1_HUMAN
NC score	0.060917 (rank : 70)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	161	Target Neighborhood Hits	546	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

MEGF8_MOUSE
NC score	0.060768 (rank : 71)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	161	Target Neighborhood Hits	520	Shared Neighborhood Hits	58
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LAMC2_MOUSE
NC score	0.059503 (rank : 72)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	161	Target Neighborhood Hits	614	Shared Neighborhood Hits	77
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

STAB1_MOUSE
NC score	0.059483 (rank : 73)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	161	Target Neighborhood Hits	566	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

AGRIN_HUMAN
NC score	0.059318 (rank : 74)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	161	Target Neighborhood Hits	582	Shared Neighborhood Hits	69
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

SMR3B_HUMAN
NC score	0.058997 (rank : 75)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	161	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

FBLN1_MOUSE
NC score	0.057683 (rank : 76)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	161	Target Neighborhood Hits	329	Shared Neighborhood Hits	50
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN1_HUMAN
NC score	0.057196 (rank : 77)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	161	Target Neighborhood Hits	324	Shared Neighborhood Hits	49
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

SPRL1_HUMAN
NC score	0.055375 (rank : 78)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	161	Target Neighborhood Hits	231	Shared Neighborhood Hits	12
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

LTBP3_MOUSE
NC score	0.055247 (rank : 79)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	161	Target Neighborhood Hits	475	Shared Neighborhood Hits	62
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP2_HUMAN
NC score	0.055116 (rank : 80)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	161	Target Neighborhood Hits	552	Shared Neighborhood Hits	70
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LAMC2_HUMAN
NC score	0.054407 (rank : 81)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	161	Target Neighborhood Hits	715	Shared Neighborhood Hits	78
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

EGF_MOUSE
NC score	0.053846 (rank : 82)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	161	Target Neighborhood Hits	358	Shared Neighborhood Hits	47
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

EGF_HUMAN
NC score	0.053505 (rank : 83)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	161	Target Neighborhood Hits	343	Shared Neighborhood Hits	44
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

TRBM_MOUSE
NC score	0.052903 (rank : 84)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	161	Target Neighborhood Hits	361	Shared Neighborhood Hits	52
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

UROM_MOUSE
NC score	0.052879 (rank : 85)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	161	Target Neighborhood Hits	276	Shared Neighborhood Hits	46
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

LTBP4_MOUSE
NC score	0.052745 (rank : 86)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	161	Target Neighborhood Hits	607	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

UROM_HUMAN
NC score	0.052557 (rank : 87)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	161	Target Neighborhood Hits	284	Shared Neighborhood Hits	40
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

NELL1_HUMAN
NC score	0.052383 (rank : 88)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	161	Target Neighborhood Hits	451	Shared Neighborhood Hits	49
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

TNR9_MOUSE
NC score	0.052077 (rank : 89)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	161	Target Neighborhood Hits	137	Shared Neighborhood Hits	47
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

C1QR1_HUMAN
NC score	0.052054 (rank : 90)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	161	Target Neighborhood Hits	493	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

TNR16_HUMAN
NC score	0.051787 (rank : 91)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	161	Target Neighborhood Hits	183	Shared Neighborhood Hits	50
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

FBLN2_HUMAN
NC score	0.051660 (rank : 92)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	161	Target Neighborhood Hits	392	Shared Neighborhood Hits	51
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

NELL2_HUMAN
NC score	0.051600 (rank : 93)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	161	Target Neighborhood Hits	449	Shared Neighborhood Hits	53
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
NC score	0.051556 (rank : 94)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	161	Target Neighborhood Hits	436	Shared Neighborhood Hits	53
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

C1QR1_MOUSE
NC score	0.051457 (rank : 95)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	161	Target Neighborhood Hits	342	Shared Neighborhood Hits	47
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

FBLN3_HUMAN
NC score	0.051382 (rank : 96)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	161	Target Neighborhood Hits	293	Shared Neighborhood Hits	46
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBN2_HUMAN
NC score	0.051230 (rank : 97)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	161	Target Neighborhood Hits	560	Shared Neighborhood Hits	71
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
NC score	0.051220 (rank : 98)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	161	Target Neighborhood Hits	543	Shared Neighborhood Hits	71
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LTBP3_HUMAN
NC score	0.050978 (rank : 99)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	161	Target Neighborhood Hits	502	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBLN2_MOUSE
NC score	0.050902 (rank : 100)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	161	Target Neighborhood Hits	505	Shared Neighborhood Hits	52
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN5_MOUSE
NC score	0.050768 (rank : 101)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	161	Target Neighborhood Hits	317	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBLN3_MOUSE
NC score	0.050757 (rank : 102)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	161	Target Neighborhood Hits	279	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN5_HUMAN
NC score	0.050498 (rank : 103)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	161	Target Neighborhood Hits	329	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FST_HUMAN
NC score	0.050470 (rank : 104)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	161	Target Neighborhood Hits	129	Shared Neighborhood Hits	21
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
NC score	0.050319 (rank : 105)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	161	Target Neighborhood Hits	146	Shared Neighborhood Hits	26
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FBN1_HUMAN
NC score	0.050293 (rank : 106)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	161	Target Neighborhood Hits	557	Shared Neighborhood Hits	69
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

TRBM_HUMAN
NC score	0.050284 (rank : 107)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	161	Target Neighborhood Hits	339	Shared Neighborhood Hits	46
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

PCSK5_MOUSE
NC score	0.050252 (rank : 108)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	161	Target Neighborhood Hits	613	Shared Neighborhood Hits	77
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

FBLN4_HUMAN
NC score	0.050214 (rank : 109)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	161	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

SPRL1_MOUSE
NC score	0.050190 (rank : 110)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	161	Target Neighborhood Hits	403	Shared Neighborhood Hits	14
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

FBN2_MOUSE
NC score	0.050139 (rank : 111)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	161	Target Neighborhood Hits	549	Shared Neighborhood Hits	67
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

TNR16_MOUSE
NC score	0.049885 (rank : 112)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	161	Target Neighborhood Hits	178	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

SREC_HUMAN
NC score	0.049340 (rank : 113)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	161	Target Neighborhood Hits	645	Shared Neighborhood Hits	69
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

WIF1_MOUSE
NC score	0.047516 (rank : 114)	θ value	0.365318 (rank : 77)
Query Neighborhood Hits	161	Target Neighborhood Hits	393	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

LAMA1_MOUSE
NC score	0.047143 (rank : 115)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	161	Target Neighborhood Hits	838	Shared Neighborhood Hits	77
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NOTC3_HUMAN
NC score	0.044913 (rank : 116)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	161	Target Neighborhood Hits	1062	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LAMA3_MOUSE
NC score	0.043934 (rank : 117)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	161	Target Neighborhood Hits	859	Shared Neighborhood Hits	73
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA1_HUMAN
NC score	0.043833 (rank : 118)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	161	Target Neighborhood Hits	804	Shared Neighborhood Hits	78
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

ZAN_MOUSE
NC score	0.043050 (rank : 119)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	161	Target Neighborhood Hits	808	Shared Neighborhood Hits	69
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

USH2A_HUMAN
NC score	0.042919 (rank : 120)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	161	Target Neighborhood Hits	600	Shared Neighborhood Hits	80
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

PCSK5_HUMAN
NC score	0.042786 (rank : 121)	θ value	1.38821 (rank : 95)
Query Neighborhood Hits	161	Target Neighborhood Hits	291	Shared Neighborhood Hits	61
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

TNR21_MOUSE
NC score	0.042559 (rank : 122)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	161	Target Neighborhood Hits	108	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

LAMC3_HUMAN
NC score	0.042384 (rank : 123)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	161	Target Neighborhood Hits	588	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

WIF1_HUMAN
NC score	0.042282 (rank : 124)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	161	Target Neighborhood Hits	392	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

DLL1_HUMAN
NC score	0.042064 (rank : 125)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	161	Target Neighborhood Hits	455	Shared Neighborhood Hits	57
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

NOTC3_MOUSE
NC score	0.041629 (rank : 126)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	161	Target Neighborhood Hits	975	Shared Neighborhood Hits	63
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

EPHB6_HUMAN
NC score	0.041549 (rank : 127)	θ value	0.0961366 (rank : 63)
Query Neighborhood Hits	161	Target Neighborhood Hits	912	Shared Neighborhood Hits	56
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

FRAS1_HUMAN
NC score	0.040912 (rank : 128)	θ value	1.06291 (rank : 89)
Query Neighborhood Hits	161	Target Neighborhood Hits	759	Shared Neighborhood Hits	68
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA2_HUMAN
NC score	0.040553 (rank : 129)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	161	Target Neighborhood Hits	1092	Shared Neighborhood Hits	78
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

TNR21_HUMAN
NC score	0.040427 (rank : 130)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	161	Target Neighborhood Hits	90	Shared Neighborhood Hits	29
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

FRAS1_MOUSE
NC score	0.039524 (rank : 131)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	161	Target Neighborhood Hits	747	Shared Neighborhood Hits	67
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

EPHB6_MOUSE
NC score	0.039121 (rank : 132)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	161	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

LAMA3_HUMAN
NC score	0.038088 (rank : 133)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	161	Target Neighborhood Hits	760	Shared Neighborhood Hits	68
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

ATRN_HUMAN
NC score	0.038002 (rank : 134)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	161	Target Neighborhood Hits	525	Shared Neighborhood Hits	53
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
NC score	0.037562 (rank : 135)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	161	Target Neighborhood Hits	519	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

EPHB3_HUMAN
NC score	0.036275 (rank : 136)	θ value	0.00228821 (rank : 48)
Query Neighborhood Hits	161	Target Neighborhood Hits	996	Shared Neighborhood Hits	47
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHB4_HUMAN
NC score	0.035556 (rank : 137)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	161	Target Neighborhood Hits	1056	Shared Neighborhood Hits	65
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

TNR3_MOUSE
NC score	0.034874 (rank : 138)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	161	Target Neighborhood Hits	113	Shared Neighborhood Hits	38
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

LAMA2_MOUSE
NC score	0.034585 (rank : 139)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	161	Target Neighborhood Hits	1198	Shared Neighborhood Hits	75
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

EPHB3_MOUSE
NC score	0.034509 (rank : 140)	θ value	0.00869519 (rank : 49)
Query Neighborhood Hits	161	Target Neighborhood Hits	996	Shared Neighborhood Hits	44
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

MKS3_HUMAN
NC score	0.033197 (rank : 141)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	161	Target Neighborhood Hits	79	Shared Neighborhood Hits	35
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

EPHB4_MOUSE
NC score	0.033182 (rank : 142)	θ value	0.21417 (rank : 70)
Query Neighborhood Hits	161	Target Neighborhood Hits	1013	Shared Neighborhood Hits	53
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHAA_HUMAN
NC score	0.033178 (rank : 143)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	161	Target Neighborhood Hits	960	Shared Neighborhood Hits	46
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHA7_HUMAN
NC score	0.032964 (rank : 144)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	161	Target Neighborhood Hits	1053	Shared Neighborhood Hits	61
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHB2_HUMAN
NC score	0.032955 (rank : 145)	θ value	0.0961366 (rank : 61)
Query Neighborhood Hits	161	Target Neighborhood Hits	983	Shared Neighborhood Hits	41
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
NC score	0.032953 (rank : 146)	θ value	0.0961366 (rank : 62)
Query Neighborhood Hits	161	Target Neighborhood Hits	982	Shared Neighborhood Hits	41
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHA6_MOUSE
NC score	0.032853 (rank : 147)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	161	Target Neighborhood Hits	946	Shared Neighborhood Hits	48
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

TNR25_HUMAN
NC score	0.032779 (rank : 148)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	161	Target Neighborhood Hits	172	Shared Neighborhood Hits	48
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

EPHA6_HUMAN
NC score	0.032402 (rank : 149)	θ value	0.47712 (rank : 78)
Query Neighborhood Hits	161	Target Neighborhood Hits	959	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

TR10C_HUMAN
NC score	0.032334 (rank : 150)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	161	Target Neighborhood Hits	105	Shared Neighborhood Hits	29
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TNR5_MOUSE
NC score	0.031945 (rank : 151)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	161	Target Neighborhood Hits	131	Shared Neighborhood Hits	35
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TENR_HUMAN
NC score	0.031018 (rank : 152)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	161	Target Neighborhood Hits	526	Shared Neighborhood Hits	64
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

EPHA2_MOUSE
NC score	0.030967 (rank : 153)	θ value	0.125558 (rank : 66)
Query Neighborhood Hits	161	Target Neighborhood Hits	1020	Shared Neighborhood Hits	52
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

WBP1_HUMAN
NC score	0.030914 (rank : 154)	θ value	0.365318 (rank : 76)
Query Neighborhood Hits	161	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q96G27, O95637	Gene names	WBP1
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 1 (WBP-1).

EPHA4_MOUSE
NC score	0.030791 (rank : 155)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	161	Target Neighborhood Hits	982	Shared Neighborhood Hits	43
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

TR19L_HUMAN
NC score	0.030657 (rank : 156)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	161	Target Neighborhood Hits	99	Shared Neighborhood Hits	30
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

PKHG4_HUMAN
NC score	0.030390 (rank : 157)	θ value	0.0330416 (rank : 55)
Query Neighborhood Hits	161	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

TENR_MOUSE
NC score	0.030295 (rank : 158)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	161	Target Neighborhood Hits	531	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

EPHA1_HUMAN
NC score	0.029742 (rank : 159)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	161	Target Neighborhood Hits	997	Shared Neighborhood Hits	53
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA1_MOUSE
NC score	0.029313 (rank : 160)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	161	Target Neighborhood Hits	958	Shared Neighborhood Hits	53
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA4_HUMAN
NC score	0.029116 (rank : 161)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	161	Target Neighborhood Hits	975	Shared Neighborhood Hits	41
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

CJ047_MOUSE
NC score	0.027839 (rank : 162)	θ value	0.62314 (rank : 82)
Query Neighborhood Hits	161	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

EPHB1_HUMAN
NC score	0.027271 (rank : 163)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	161	Target Neighborhood Hits	988	Shared Neighborhood Hits	48
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

NLTP_HUMAN
NC score	0.027102 (rank : 164)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	161	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	P22307, Q15432, Q16622, Q99430	Gene names	SCP2
Domain Architecture
Description	Nonspecific lipid-transfer protein (EC 2.3.1.176) (Propanoyl-CoA C- acyltransferase) (NSL-TP) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) (SCP-chi) (SCPX).

EPHA2_HUMAN
NC score	0.027020 (rank : 165)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	161	Target Neighborhood Hits	1021	Shared Neighborhood Hits	48
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

NLTP_MOUSE
NC score	0.026957 (rank : 166)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	161	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P32020, Q9DBM7	Gene names	Scp2, Scp-2
Domain Architecture
Description	Nonspecific lipid-transfer protein (EC 2.3.1.176) (Propanoyl-CoA C- acyltransferase) (NSL-TP) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) (SCP-chi) (SCPX).

MKS3_MOUSE
NC score	0.026275 (rank : 167)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	161	Target Neighborhood Hits	89	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

KR102_HUMAN
NC score	0.025992 (rank : 168)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	161	Target Neighborhood Hits	264	Shared Neighborhood Hits	36
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

TR10B_HUMAN
NC score	0.025891 (rank : 169)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	161	Target Neighborhood Hits	71	Shared Neighborhood Hits	24
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

SSPO_MOUSE
NC score	0.022168 (rank : 170)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	161	Target Neighborhood Hits	800	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

AASS_HUMAN
NC score	0.020346 (rank : 171)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	161	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UDR5, O95462	Gene names	AASS
Domain Architecture
Description	Alpha-aminoadipic semialdehyde synthase, mitochondrial precursor (LKR/SDH) [Includes: Lysine ketoglutarate reductase (EC 1.5.1.8) (LOR) (LKR); Saccharopine dehydrogenase (EC 1.5.1.9) (SDH)].

RSPO1_HUMAN
NC score	0.017820 (rank : 172)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	161	Target Neighborhood Hits	101	Shared Neighborhood Hits	21
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

FUT1_MOUSE
NC score	0.016497 (rank : 173)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	161	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	O09160	Gene names	Fut1
Domain Architecture
Description	Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (GDP-L- fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1) (Alpha(1,2)FT 1) (Fucosyltransferase 1).

CELR1_HUMAN
NC score	0.015192 (rank : 174)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	161	Target Neighborhood Hits	613	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

NDUB9_HUMAN
NC score	0.014169 (rank : 175)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	161	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6M9, Q9UQE8	Gene names	NDUFB9, UQOR22
Domain Architecture
Description	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase B22 subunit) (Complex I-B22) (CI-B22).

TNR27_MOUSE
NC score	0.013917 (rank : 176)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	161	Target Neighborhood Hits	61	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

KR261_HUMAN
NC score	0.013561 (rank : 177)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

APBB2_HUMAN
NC score	0.012860 (rank : 178)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	161	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

APBB2_MOUSE
NC score	0.011557 (rank : 179)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	161	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

DIAP2_HUMAN
NC score	0.011052 (rank : 180)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	161	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

PUS7_HUMAN
NC score	0.010666 (rank : 181)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	161	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PZ0, Q75MG4, Q9NX19	Gene names	PUS7, KIAA1897
Domain Architecture
Description	Pseudouridylate synthase 7 homolog (EC 5.4.99.-).

RGS3_HUMAN
NC score	0.009688 (rank : 182)	θ value	0.21417 (rank : 71)
Query Neighborhood Hits	161	Target Neighborhood Hits	1375	Shared Neighborhood Hits	11
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

LRP12_HUMAN
NC score	0.009461 (rank : 183)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	161	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

SNX6_HUMAN
NC score	0.009045 (rank : 184)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNH7, Q9Y449	Gene names	SNX6
Domain Architecture
Description	Sorting nexin-6 (TRAF4-associated factor 2).

SNX6_MOUSE
NC score	0.009036 (rank : 185)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P8X1	Gene names	Snx6
Domain Architecture	No domain graphic available
Description	Sorting nexin-6.

RABX5_HUMAN
NC score	0.008273 (rank : 186)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

CSTN2_HUMAN
NC score	0.007137 (rank : 187)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	161	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4D0, Q9BSS0	Gene names	CLSTN2, CS2
Domain Architecture
Description	Calsyntenin-2 precursor.

CASR_HUMAN
NC score	0.007091 (rank : 188)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	161	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

ARI4A_HUMAN
NC score	0.006795 (rank : 189)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	161	Target Neighborhood Hits	434	Shared Neighborhood Hits	3
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CRIS1_MOUSE
NC score	0.005049 (rank : 190)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	161	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q03401	Gene names	Crisp1, Aeg-1, Aeg1
Domain Architecture
Description	Cysteine-rich secretory protein 1 precursor (CRISP-1) (Acidic epididymal glycoprotein 1) (Sperm-coating glycoprotein 1) (SCP 1).

TEP1_HUMAN
NC score	0.004658 (rank : 191)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	161	Target Neighborhood Hits	371	Shared Neighborhood Hits	2
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

GAK8_HUMAN
NC score	0.003838 (rank : 192)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	161	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HDB9	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(II) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

AN32A_HUMAN
NC score	0.002572 (rank : 193)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	161	Target Neighborhood Hits	234	Shared Neighborhood Hits	2
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

MMP17_MOUSE
NC score	0.001133 (rank : 194)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

PCDG4_HUMAN
NC score	-0.000202 (rank : 195)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	161	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5G9, Q9Y5D3	Gene names	PCDHGA4
Domain Architecture
Description	Protocadherin gamma A4 precursor (PCDH-gamma-A4).

PCDG5_HUMAN
NC score	-0.000218 (rank : 196)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	161	Target Neighborhood Hits	159	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5G8, Q9Y5D2	Gene names	PCDHGA5
Domain Architecture
Description	Protocadherin gamma A5 precursor (PCDH-gamma-A5).

ANR26_HUMAN
NC score	-0.004241 (rank : 197)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	161	Target Neighborhood Hits	1614	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.