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Network neighborhood for query Sequence : EST2_HUMAN

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EST2_HUMAN
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EST2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

CES3_MOUSE
θ value	3.51195e-137 (rank : 2)	NC score	0.989491 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VCT4, Q91ZV9, Q924V8, Q9ULY1	Gene names	Ces3, Ces1
Domain Architecture	No domain graphic available
Description	Carboxylesterase 3 precursor (EC 3.1.1.1) (Triacylglycerol hydrolase) (TGH).

EST22_MOUSE
θ value	2.51683e-135 (rank : 3)	NC score	0.990098 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	27
SwissProt Accessions	Q64176	Gene names	Es22
Domain Architecture
Description	Liver carboxylesterase 22 precursor (EC 3.1.1.1) (Egasyn) (Esterase- 22) (Es-22).

EST1_MOUSE
θ value	8.9516e-133 (rank : 4)	NC score	0.988579 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	28	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

EST1_HUMAN
θ value	1.29261e-131 (rank : 5)	NC score	0.989325 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	P23141, Q00015, Q13657, Q14062, Q16737, Q16788, Q86UK2, Q96EE8, Q9UK77, Q9ULY2	Gene names	CES1, CES2, SES1
Domain Architecture
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ACAT) (Monocyte/macrophage serine esterase) (HMSE) (Serine esterase 1) (Brain carboxylesterase hBr1) (Triacylglycerol hydrolase) (TGH) (Egasyn).

ESTN_MOUSE
θ value	4.5974e-129 (rank : 6)	NC score	0.989669 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

EST31_MOUSE
θ value	1.69212e-123 (rank : 7)	NC score	0.991403 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	Q63880	Gene names	Es31
Domain Architecture
Description	Liver carboxylesterase 31 precursor (EC 3.1.1.1) (ES-Male) (Esterase- 31).

NLGNX_HUMAN
θ value	1.95861e-79 (rank : 8)	NC score	0.947250 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

NLGNY_HUMAN
θ value	1.65806e-78 (rank : 9)	NC score	0.947040 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

NLGN2_MOUSE
θ value	2.1655e-78 (rank : 10)	NC score	0.951118 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	49	Shared Neighborhood Hits	27
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGN3_MOUSE
θ value	8.22888e-78 (rank : 11)	NC score	0.946899 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

ACES_HUMAN
θ value	4.08394e-77 (rank : 12)	NC score	0.963808 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

NLGN2_HUMAN
θ value	4.08394e-77 (rank : 13)	NC score	0.950852 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

ACES_MOUSE
θ value	2.02684e-76 (rank : 14)	NC score	0.962944 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

NLGN3_HUMAN
θ value	4.99229e-75 (rank : 15)	NC score	0.945731 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGN1_MOUSE
θ value	6.10265e-73 (rank : 16)	NC score	0.945717 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q99K10	Gene names	Nlgn1, Kiaa1070
Domain Architecture
Description	Neuroligin-1 precursor.

CHLE_MOUSE
θ value	1.04096e-72 (rank : 17)	NC score	0.961137 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

NLGN1_HUMAN
θ value	1.35953e-72 (rank : 18)	NC score	0.945595 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.

CHLE_HUMAN
θ value	4.83544e-70 (rank : 19)	NC score	0.961375 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	P06276	Gene names	BCHE, CHE1
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

CEL_MOUSE
θ value	1.0458e-56 (rank : 20)	NC score	0.957239 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	28	Shared Neighborhood Hits	25
SwissProt Accessions	Q64285	Gene names	Cel, Lip1
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CEL_HUMAN
θ value	5.19021e-56 (rank : 21)	NC score	0.728196 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	896	Shared Neighborhood Hits	30
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

THYG_MOUSE
θ value	1.15895e-47 (rank : 22)	NC score	0.829779 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	161	Shared Neighborhood Hits	23
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

THYG_HUMAN
θ value	3.48949e-44 (rank : 23)	NC score	0.815758 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	154	Shared Neighborhood Hits	23
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

AAAD_HUMAN
θ value	0.00298849 (rank : 24)	NC score	0.274503 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	P22760, Q8N1A9	Gene names	AADAC, DAC
Domain Architecture
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

DPP8_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.050373 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q6V1X1, Q7Z4C8, Q7Z4D3, Q7Z4E1, Q8IWG7, Q8NEM5, Q96JX1, Q9HBM2, Q9HBM3, Q9HBM4, Q9HBM5, Q9NXF4	Gene names	DPP8, DPRP1
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8) (Prolyl dipeptidase DPP8) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1).

DPP8_MOUSE
θ value	0.279714 (rank : 26)	NC score	0.047524 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q80YA7, Q9D4G6	Gene names	Dpp8
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8).

APEH_MOUSE
θ value	0.47712 (rank : 27)	NC score	0.027246 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R146, Q8K029, Q8R0M9	Gene names	Apeh
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase).

CK5P1_HUMAN
θ value	0.813845 (rank : 28)	NC score	0.019824 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q96SZ6, Q5QP47, Q9BVG6, Q9BWZ5, Q9H859, Q9NZZ9, Q9Y3F0	Gene names	CDK5RAP1
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 1 (CDK5 activator-binding protein C42).

K0460_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.029141 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

AAAD_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.174560 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

DPP9_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.042751 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q86TI2, Q6AI37, Q6UAL0, Q6ZMT2, Q6ZNJ5, Q8N2J7, Q8N3F5, Q8WXD8, Q96NT8, Q9BVR3	Gene names	DPP9, DPRP2
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2).

DPP9_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.037725 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BVG4, Q6KAM9, Q8BWT9	Gene names	Dpp9
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9).

ATS12_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.002253 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	220	Shared Neighborhood Hits	2
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

BAG4_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.017699 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

CPSF6_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.057147 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	359	Shared Neighborhood Hits	10
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.060405 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	356	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

K0460_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.029634 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	374	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

OL148_MOUSE
θ value	8.99809 (rank : 38)	NC score	-0.003523 (rank : 39)
Query Neighborhood Hits	38	Target Neighborhood Hits	719	Shared Neighborhood Hits	2
SwissProt Accessions	Q60887, Q9EQ88	Gene names	Olfr148, Mor224-4, Olfr7
Domain Architecture	No domain graphic available
Description	Olfactory receptor 148 (Olfactory receptor 7F) (Olfactory receptor 224-4) (Odorant receptor M30).

SMR3B_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.071993 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

Hits sorted by NC score

EST2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

EST31_MOUSE
NC score	0.991403 (rank : 2)	θ value	1.69212e-123 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	Q63880	Gene names	Es31
Domain Architecture
Description	Liver carboxylesterase 31 precursor (EC 3.1.1.1) (ES-Male) (Esterase- 31).

EST22_MOUSE
NC score	0.990098 (rank : 3)	θ value	2.51683e-135 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	27
SwissProt Accessions	Q64176	Gene names	Es22
Domain Architecture
Description	Liver carboxylesterase 22 precursor (EC 3.1.1.1) (Egasyn) (Esterase- 22) (Es-22).

ESTN_MOUSE
NC score	0.989669 (rank : 4)	θ value	4.5974e-129 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

CES3_MOUSE
NC score	0.989491 (rank : 5)	θ value	3.51195e-137 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VCT4, Q91ZV9, Q924V8, Q9ULY1	Gene names	Ces3, Ces1
Domain Architecture	No domain graphic available
Description	Carboxylesterase 3 precursor (EC 3.1.1.1) (Triacylglycerol hydrolase) (TGH).

EST1_HUMAN
NC score	0.989325 (rank : 6)	θ value	1.29261e-131 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	P23141, Q00015, Q13657, Q14062, Q16737, Q16788, Q86UK2, Q96EE8, Q9UK77, Q9ULY2	Gene names	CES1, CES2, SES1
Domain Architecture
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ACAT) (Monocyte/macrophage serine esterase) (HMSE) (Serine esterase 1) (Brain carboxylesterase hBr1) (Triacylglycerol hydrolase) (TGH) (Egasyn).

EST1_MOUSE
NC score	0.988579 (rank : 7)	θ value	8.9516e-133 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	28	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

ACES_HUMAN
NC score	0.963808 (rank : 8)	θ value	4.08394e-77 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

ACES_MOUSE
NC score	0.962944 (rank : 9)	θ value	2.02684e-76 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

CHLE_HUMAN
NC score	0.961375 (rank : 10)	θ value	4.83544e-70 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	P06276	Gene names	BCHE, CHE1
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

CHLE_MOUSE
NC score	0.961137 (rank : 11)	θ value	1.04096e-72 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

CEL_MOUSE
NC score	0.957239 (rank : 12)	θ value	1.0458e-56 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	28	Shared Neighborhood Hits	25
SwissProt Accessions	Q64285	Gene names	Cel, Lip1
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

NLGN2_MOUSE
NC score	0.951118 (rank : 13)	θ value	2.1655e-78 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	49	Shared Neighborhood Hits	27
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGN2_HUMAN
NC score	0.950852 (rank : 14)	θ value	4.08394e-77 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGNX_HUMAN
NC score	0.947250 (rank : 15)	θ value	1.95861e-79 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

NLGNY_HUMAN
NC score	0.947040 (rank : 16)	θ value	1.65806e-78 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

NLGN3_MOUSE
NC score	0.946899 (rank : 17)	θ value	8.22888e-78 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGN3_HUMAN
NC score	0.945731 (rank : 18)	θ value	4.99229e-75 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGN1_MOUSE
NC score	0.945717 (rank : 19)	θ value	6.10265e-73 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q99K10	Gene names	Nlgn1, Kiaa1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN1_HUMAN
NC score	0.945595 (rank : 20)	θ value	1.35953e-72 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.

THYG_MOUSE
NC score	0.829779 (rank : 21)	θ value	1.15895e-47 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	161	Shared Neighborhood Hits	23
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

THYG_HUMAN
NC score	0.815758 (rank : 22)	θ value	3.48949e-44 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	154	Shared Neighborhood Hits	23
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

CEL_HUMAN
NC score	0.728196 (rank : 23)	θ value	5.19021e-56 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	896	Shared Neighborhood Hits	30
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

AAAD_HUMAN
NC score	0.274503 (rank : 24)	θ value	0.00298849 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	P22760, Q8N1A9	Gene names	AADAC, DAC
Domain Architecture
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

AAAD_MOUSE
NC score	0.174560 (rank : 25)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

SMR3B_HUMAN
NC score	0.071993 (rank : 26)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	38	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

CPSF6_MOUSE
NC score	0.060405 (rank : 27)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	356	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CPSF6_HUMAN
NC score	0.057147 (rank : 28)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	359	Shared Neighborhood Hits	10
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

DPP8_HUMAN
NC score	0.050373 (rank : 29)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q6V1X1, Q7Z4C8, Q7Z4D3, Q7Z4E1, Q8IWG7, Q8NEM5, Q96JX1, Q9HBM2, Q9HBM3, Q9HBM4, Q9HBM5, Q9NXF4	Gene names	DPP8, DPRP1
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8) (Prolyl dipeptidase DPP8) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1).

DPP8_MOUSE
NC score	0.047524 (rank : 30)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q80YA7, Q9D4G6	Gene names	Dpp8
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8).

DPP9_HUMAN
NC score	0.042751 (rank : 31)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q86TI2, Q6AI37, Q6UAL0, Q6ZMT2, Q6ZNJ5, Q8N2J7, Q8N3F5, Q8WXD8, Q96NT8, Q9BVR3	Gene names	DPP9, DPRP2
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2).

DPP9_MOUSE
NC score	0.037725 (rank : 32)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BVG4, Q6KAM9, Q8BWT9	Gene names	Dpp9
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9).

K0460_MOUSE
NC score	0.029634 (rank : 33)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	374	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

K0460_HUMAN
NC score	0.029141 (rank : 34)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

APEH_MOUSE
NC score	0.027246 (rank : 35)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R146, Q8K029, Q8R0M9	Gene names	Apeh
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase).

CK5P1_HUMAN
NC score	0.019824 (rank : 36)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q96SZ6, Q5QP47, Q9BVG6, Q9BWZ5, Q9H859, Q9NZZ9, Q9Y3F0	Gene names	CDK5RAP1
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 1 (CDK5 activator-binding protein C42).

BAG4_HUMAN
NC score	0.017699 (rank : 37)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

ATS12_MOUSE
NC score	0.002253 (rank : 38)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	220	Shared Neighborhood Hits	2
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

OL148_MOUSE
NC score	-0.003523 (rank : 39)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	719	Shared Neighborhood Hits	2
SwissProt Accessions	Q60887, Q9EQ88	Gene names	Olfr148, Mor224-4, Olfr7
Domain Architecture	No domain graphic available
Description	Olfactory receptor 148 (Olfactory receptor 7F) (Olfactory receptor 224-4) (Odorant receptor M30).