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Network neighborhood for query Sequence : APEH_MOUSE

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APEH_MOUSE
SwissProt Accessions	Q8R146, Q8K029, Q8R0M9	Gene names	Apeh
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ACPH_HUMAN
θ value	0 (rank : 1)	NC score	0.993800 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P13798, Q9BQ33, Q9P0Y2	Gene names	APEH
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH) (DNF15S2 protein).

APEH_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R146, Q8K029, Q8R0M9	Gene names	Apeh
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase).

DPP9_MOUSE
θ value	4.59992e-12 (rank : 3)	NC score	0.489772 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BVG4, Q6KAM9, Q8BWT9	Gene names	Dpp9
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9).

DPP9_HUMAN
θ value	1.33837e-11 (rank : 4)	NC score	0.486773 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q86TI2, Q6AI37, Q6UAL0, Q6ZMT2, Q6ZNJ5, Q8N2J7, Q8N3F5, Q8WXD8, Q96NT8, Q9BVR3	Gene names	DPP9, DPRP2
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2).

DPP8_HUMAN
θ value	1.80886e-08 (rank : 5)	NC score	0.453917 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	17
SwissProt Accessions	Q6V1X1, Q7Z4C8, Q7Z4D3, Q7Z4E1, Q8IWG7, Q8NEM5, Q96JX1, Q9HBM2, Q9HBM3, Q9HBM4, Q9HBM5, Q9NXF4	Gene names	DPP8, DPRP1
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8) (Prolyl dipeptidase DPP8) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1).

DPP8_MOUSE
θ value	1.80886e-08 (rank : 6)	NC score	0.453285 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	Q80YA7, Q9D4G6	Gene names	Dpp8
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8).

SEPR_HUMAN
θ value	4.45536e-07 (rank : 7)	NC score	0.397019 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	Q12884, O00199, Q86Z29, Q99998, Q9UID4	Gene names	FAP
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease) (170 kDa melanoma membrane-bound gelatinase).

DPP6_HUMAN
θ value	5.81887e-07 (rank : 8)	NC score	0.393911 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	P42658	Gene names	DPP6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

DPP6_MOUSE
θ value	5.81887e-07 (rank : 9)	NC score	0.393058 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z218, Q9QWW2, Q9Z219	Gene names	Dpp6, Dpp-6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

SEPR_MOUSE
θ value	9.92553e-07 (rank : 10)	NC score	0.400551 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	P97321	Gene names	Fap
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease).

DPP4_MOUSE
θ value	0.000270298 (rank : 11)	NC score	0.369774 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	P28843, Q3U514	Gene names	Dpp4, Cd26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

PPCE_MOUSE
θ value	0.00298849 (rank : 12)	NC score	0.183638 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QUR6, Q80YS1	Gene names	Prep, Pep
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).

DPP10_MOUSE
θ value	0.00869519 (rank : 13)	NC score	0.349598 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NXK7, Q6P554, Q8K1H0	Gene names	Dpp10
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X).

PPCE_HUMAN
θ value	0.00869519 (rank : 14)	NC score	0.177700 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	P48147	Gene names	PREP, PEP
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).

DPP10_HUMAN
θ value	0.0148317 (rank : 15)	NC score	0.343063 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

DPP4_HUMAN
θ value	0.0193708 (rank : 16)	NC score	0.351371 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	P27487	Gene names	DPP4, ADCP2, CD26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

EST2_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.027246 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	38	Shared Neighborhood Hits	6
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

O10AG_HUMAN
θ value	1.06291 (rank : 18)	NC score	0.004714 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	731	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NH19, Q6IEU3	Gene names	OR10AG1
Domain Architecture
Description	Olfactory receptor 10AG1 (Olfactory receptor OR11-160).

O11L1_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.004476 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	741	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NGX0	Gene names	OR11L1
Domain Architecture
Description	Olfactory receptor 11L1.

OR2M2_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.004726 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	769	Shared Neighborhood Hits	5
SwissProt Accessions	Q96R28	Gene names	OR2M2
Domain Architecture	No domain graphic available
Description	Olfactory receptor 2M2 (OST423).

PGK2_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.055219 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P09041, Q6P8V2	Gene names	Pgk2, Pgk-2
Domain Architecture
Description	Phosphoglycerate kinase, testis specific (EC 2.7.2.3).

P3H3_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.020509 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CG70, O88836	Gene names	Leprel2, P3h3
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 3 precursor (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B).

PGK2_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.055186 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P07205, Q9H107	Gene names	PGK2, PGKB
Domain Architecture
Description	Phosphoglycerate kinase, testis specific (EC 2.7.2.3).

TNC6B_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.028300 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	256	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

MCM3A_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.022949 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

OR2M3_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.004973 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	780	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NG83, Q6IEY0	Gene names	OR2M3, OR2M6
Domain Architecture
Description	Olfactory receptor 2M3 (Olfactory receptor OR1-54).

CLIC6_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.011082 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	289	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

PHLD2_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.027678 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q15127	Gene names	GPLD2, PIGPLD2
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 2 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

TBCD3_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.023405 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

ACOT5_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.010344 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q6Q2Z6	Gene names	Acot5
Domain Architecture	No domain graphic available
Description	Acyl-coenzyme A thioesterase 5 (EC 3.1.2.2) (Acyl-CoA thioesterase 5) (Peroxisomal acyl-coenzyme A thioester hydrolase Ic) (Peroxisomal acyl-CoA thioesterase Ic).

DHX57_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.008633 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DPP2_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.015466 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHL4, Q969X4	Gene names	DPP7, DPP2, QPP
Domain Architecture
Description	Dipeptidyl-peptidase 2 precursor (EC 3.4.14.2) (Dipeptidyl-peptidase II) (DPP II) (Dipeptidyl aminopeptidase II) (Quiescent cell proline dipeptidase) (Dipeptidyl peptidase 7).

PGK1_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.041867 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P00558, Q6IBT6, Q8NI87	Gene names	PGK1, PGKA
Domain Architecture
Description	Phosphoglycerate kinase 1 (EC 2.7.2.3) (Primer recognition protein 2) (PRP 2).

PHLD1_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.025580 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	P80108, Q15128	Gene names	GPLD1, PIGPLD1
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 1 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

UBP6_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.012836 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

WDR35_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.015562 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BND3, Q8CDL4	Gene names	Wdr35
Domain Architecture
Description	WD repeat protein 35.

CT135_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.036067 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3Z7	Gene names	C20orf135
Domain Architecture
Description	Uncharacterized protein C20orf135.

SMAD7_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.016200 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	O15105, O14740, Q6DK23	Gene names	SMAD7, MADH7, MADH8
Domain Architecture
Description	Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against DPP homolog 7) (Smad7) (hSMAD7).

SMAD7_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.016220 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	O35253, O88709	Gene names	Smad7, Madh7
Domain Architecture
Description	Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against DPP homolog 7) (Smad7) (Madh8).

BPHL_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.015213 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q86WA6, Q00306, Q13855	Gene names	BPHL
Domain Architecture
Description	Valacyclovir hydrolase precursor (EC 3.1.-.-) (VACVase) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA).

MPH6_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.018047 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D1Q1	Gene names	Mphosph6
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 6.

PGK1_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.039300 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P09411	Gene names	Pgk1, Pgk-1
Domain Architecture
Description	Phosphoglycerate kinase 1 (EC 2.7.2.3).

Hits sorted by NC score

APEH_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R146, Q8K029, Q8R0M9	Gene names	Apeh
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase).

ACPH_HUMAN
NC score	0.993800 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	P13798, Q9BQ33, Q9P0Y2	Gene names	APEH
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase) (Oxidized protein hydrolase) (OPH) (DNF15S2 protein).

DPP9_MOUSE
NC score	0.489772 (rank : 3)	θ value	4.59992e-12 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BVG4, Q6KAM9, Q8BWT9	Gene names	Dpp9
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9).

DPP9_HUMAN
NC score	0.486773 (rank : 4)	θ value	1.33837e-11 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q86TI2, Q6AI37, Q6UAL0, Q6ZMT2, Q6ZNJ5, Q8N2J7, Q8N3F5, Q8WXD8, Q96NT8, Q9BVR3	Gene names	DPP9, DPRP2
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2).

DPP8_HUMAN
NC score	0.453917 (rank : 5)	θ value	1.80886e-08 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	17
SwissProt Accessions	Q6V1X1, Q7Z4C8, Q7Z4D3, Q7Z4E1, Q8IWG7, Q8NEM5, Q96JX1, Q9HBM2, Q9HBM3, Q9HBM4, Q9HBM5, Q9NXF4	Gene names	DPP8, DPRP1
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8) (Prolyl dipeptidase DPP8) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1).

DPP8_MOUSE
NC score	0.453285 (rank : 6)	θ value	1.80886e-08 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	Q80YA7, Q9D4G6	Gene names	Dpp8
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8).

SEPR_MOUSE
NC score	0.400551 (rank : 7)	θ value	9.92553e-07 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	P97321	Gene names	Fap
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease).

SEPR_HUMAN
NC score	0.397019 (rank : 8)	θ value	4.45536e-07 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	Q12884, O00199, Q86Z29, Q99998, Q9UID4	Gene names	FAP
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease) (170 kDa melanoma membrane-bound gelatinase).

DPP6_HUMAN
NC score	0.393911 (rank : 9)	θ value	5.81887e-07 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	P42658	Gene names	DPP6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

DPP6_MOUSE
NC score	0.393058 (rank : 10)	θ value	5.81887e-07 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z218, Q9QWW2, Q9Z219	Gene names	Dpp6, Dpp-6
Domain Architecture
Description	Dipeptidyl aminopeptidase-like protein 6 (Dipeptidylpeptidase VI) (Dipeptidylpeptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl aminopeptidase-related protein) (DPPX).

DPP4_MOUSE
NC score	0.369774 (rank : 11)	θ value	0.000270298 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	P28843, Q3U514	Gene names	Dpp4, Cd26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (Thymocyte-activating molecule) (THAM) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

DPP4_HUMAN
NC score	0.351371 (rank : 12)	θ value	0.0193708 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	P27487	Gene names	DPP4, ADCP2, CD26
Domain Architecture
Description	Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].

DPP10_MOUSE
NC score	0.349598 (rank : 13)	θ value	0.00869519 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NXK7, Q6P554, Q8K1H0	Gene names	Dpp10
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X).

DPP10_HUMAN
NC score	0.343063 (rank : 14)	θ value	0.0148317 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N608, Q6TTV4, Q86YR9, Q9P236	Gene names	DPP10, DPRP3, KIAA1492
Domain Architecture	No domain graphic available
Description	Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (Dipeptidyl peptidase-like protein 2) (DPL2) (Dipeptidyl peptidase IV-related protein 3) (DPRP-3).

PPCE_MOUSE
NC score	0.183638 (rank : 15)	θ value	0.00298849 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QUR6, Q80YS1	Gene names	Prep, Pep
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).

PPCE_HUMAN
NC score	0.177700 (rank : 16)	θ value	0.00869519 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	P48147	Gene names	PREP, PEP
Domain Architecture
Description	Prolyl endopeptidase (EC 3.4.21.26) (Post-proline cleaving enzyme) (PE).

PGK2_MOUSE
NC score	0.055219 (rank : 17)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P09041, Q6P8V2	Gene names	Pgk2, Pgk-2
Domain Architecture
Description	Phosphoglycerate kinase, testis specific (EC 2.7.2.3).

PGK2_HUMAN
NC score	0.055186 (rank : 18)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P07205, Q9H107	Gene names	PGK2, PGKB
Domain Architecture
Description	Phosphoglycerate kinase, testis specific (EC 2.7.2.3).

PGK1_HUMAN
NC score	0.041867 (rank : 19)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P00558, Q6IBT6, Q8NI87	Gene names	PGK1, PGKA
Domain Architecture
Description	Phosphoglycerate kinase 1 (EC 2.7.2.3) (Primer recognition protein 2) (PRP 2).

PGK1_MOUSE
NC score	0.039300 (rank : 20)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P09411	Gene names	Pgk1, Pgk-1
Domain Architecture
Description	Phosphoglycerate kinase 1 (EC 2.7.2.3).

CT135_HUMAN
NC score	0.036067 (rank : 21)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3Z7	Gene names	C20orf135
Domain Architecture
Description	Uncharacterized protein C20orf135.

TNC6B_HUMAN
NC score	0.028300 (rank : 22)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	256	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

PHLD2_HUMAN
NC score	0.027678 (rank : 23)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q15127	Gene names	GPLD2, PIGPLD2
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 2 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

EST2_HUMAN
NC score	0.027246 (rank : 24)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	38	Shared Neighborhood Hits	6
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

PHLD1_HUMAN
NC score	0.025580 (rank : 25)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	P80108, Q15128	Gene names	GPLD1, PIGPLD1
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 1 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

TBCD3_HUMAN
NC score	0.023405 (rank : 26)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

MCM3A_MOUSE
NC score	0.022949 (rank : 27)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

P3H3_MOUSE
NC score	0.020509 (rank : 28)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CG70, O88836	Gene names	Leprel2, P3h3
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 3 precursor (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B).

MPH6_MOUSE
NC score	0.018047 (rank : 29)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D1Q1	Gene names	Mphosph6
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 6.

SMAD7_MOUSE
NC score	0.016220 (rank : 30)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	O35253, O88709	Gene names	Smad7, Madh7
Domain Architecture
Description	Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against DPP homolog 7) (Smad7) (Madh8).

SMAD7_HUMAN
NC score	0.016200 (rank : 31)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	O15105, O14740, Q6DK23	Gene names	SMAD7, MADH7, MADH8
Domain Architecture
Description	Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against DPP homolog 7) (Smad7) (hSMAD7).

WDR35_MOUSE
NC score	0.015562 (rank : 32)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BND3, Q8CDL4	Gene names	Wdr35
Domain Architecture
Description	WD repeat protein 35.

DPP2_HUMAN
NC score	0.015466 (rank : 33)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHL4, Q969X4	Gene names	DPP7, DPP2, QPP
Domain Architecture
Description	Dipeptidyl-peptidase 2 precursor (EC 3.4.14.2) (Dipeptidyl-peptidase II) (DPP II) (Dipeptidyl aminopeptidase II) (Quiescent cell proline dipeptidase) (Dipeptidyl peptidase 7).

BPHL_HUMAN
NC score	0.015213 (rank : 34)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q86WA6, Q00306, Q13855	Gene names	BPHL
Domain Architecture
Description	Valacyclovir hydrolase precursor (EC 3.1.-.-) (VACVase) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA).

UBP6_HUMAN
NC score	0.012836 (rank : 35)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

CLIC6_HUMAN
NC score	0.011082 (rank : 36)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	289	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

ACOT5_MOUSE
NC score	0.010344 (rank : 37)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q6Q2Z6	Gene names	Acot5
Domain Architecture	No domain graphic available
Description	Acyl-coenzyme A thioesterase 5 (EC 3.1.2.2) (Acyl-CoA thioesterase 5) (Peroxisomal acyl-coenzyme A thioester hydrolase Ic) (Peroxisomal acyl-CoA thioesterase Ic).

DHX57_HUMAN
NC score	0.008633 (rank : 38)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

OR2M3_HUMAN
NC score	0.004973 (rank : 39)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	780	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NG83, Q6IEY0	Gene names	OR2M3, OR2M6
Domain Architecture
Description	Olfactory receptor 2M3 (Olfactory receptor OR1-54).

OR2M2_HUMAN
NC score	0.004726 (rank : 40)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	769	Shared Neighborhood Hits	5
SwissProt Accessions	Q96R28	Gene names	OR2M2
Domain Architecture	No domain graphic available
Description	Olfactory receptor 2M2 (OST423).

O10AG_HUMAN
NC score	0.004714 (rank : 41)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	731	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NH19, Q6IEU3	Gene names	OR10AG1
Domain Architecture
Description	Olfactory receptor 10AG1 (Olfactory receptor OR11-160).

O11L1_HUMAN
NC score	0.004476 (rank : 42)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	741	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NGX0	Gene names	OR11L1
Domain Architecture
Description	Olfactory receptor 11L1.