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Network neighborhood for query Sequence : UBP6_HUMAN

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UBP6_HUMAN
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TBCD3_HUMAN
θ value	0 (rank : 1)	NC score	0.603453 (rank : 36)
Query Neighborhood Hits	188	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

UBP32_HUMAN
θ value	0 (rank : 2)	NC score	0.798173 (rank : 2)
Query Neighborhood Hits	188	Target Neighborhood Hits	170	Shared Neighborhood Hits	82
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP6_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	188	Target Neighborhood Hits	188	Shared Neighborhood Hits	188
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

US6NL_MOUSE
θ value	2.09745e-73 (rank : 4)	NC score	0.520774 (rank : 47)
Query Neighborhood Hits	188	Target Neighborhood Hits	157	Shared Neighborhood Hits	29
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

UBP15_HUMAN
θ value	9.74306e-71 (rank : 5)	NC score	0.785633 (rank : 7)
Query Neighborhood Hits	188	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

US6NL_HUMAN
θ value	1.66191e-70 (rank : 6)	NC score	0.515403 (rank : 51)
Query Neighborhood Hits	188	Target Neighborhood Hits	201	Shared Neighborhood Hits	27
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

UBP15_MOUSE
θ value	6.31527e-70 (rank : 7)	NC score	0.785772 (rank : 6)
Query Neighborhood Hits	188	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP4_HUMAN
θ value	4.52582e-68 (rank : 8)	NC score	0.788528 (rank : 4)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP4_MOUSE
θ value	1.71981e-67 (rank : 9)	NC score	0.788271 (rank : 5)
Query Neighborhood Hits	188	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP11_HUMAN
θ value	1.11475e-66 (rank : 10)	NC score	0.793764 (rank : 3)
Query Neighborhood Hits	188	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP8_HUMAN
θ value	2.11701e-41 (rank : 11)	NC score	0.692183 (rank : 18)
Query Neighborhood Hits	188	Target Neighborhood Hits	751	Shared Neighborhood Hits	81
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP8_MOUSE
θ value	6.81017e-40 (rank : 12)	NC score	0.725560 (rank : 11)
Query Neighborhood Hits	188	Target Neighborhood Hits	362	Shared Neighborhood Hits	78
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP2_MOUSE
θ value	2.42216e-37 (rank : 13)	NC score	0.744957 (rank : 8)
Query Neighborhood Hits	188	Target Neighborhood Hits	86	Shared Neighborhood Hits	74
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_HUMAN
θ value	7.04741e-37 (rank : 14)	NC score	0.742674 (rank : 9)
Query Neighborhood Hits	188	Target Neighborhood Hits	84	Shared Neighborhood Hits	73
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP21_MOUSE
θ value	1.73987e-27 (rank : 15)	NC score	0.727644 (rank : 10)
Query Neighborhood Hits	188	Target Neighborhood Hits	101	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP21_HUMAN
θ value	2.51237e-26 (rank : 16)	NC score	0.725054 (rank : 12)
Query Neighborhood Hits	188	Target Neighborhood Hits	95	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP43_HUMAN
θ value	3.07116e-24 (rank : 17)	NC score	0.706191 (rank : 15)
Query Neighborhood Hits	188	Target Neighborhood Hits	144	Shared Neighborhood Hits	79
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

TBC10_HUMAN
θ value	5.23862e-24 (rank : 18)	NC score	0.450629 (rank : 64)
Query Neighborhood Hits	188	Target Neighborhood Hits	64	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

TBC10_MOUSE
θ value	3.39556e-23 (rank : 19)	NC score	0.447868 (rank : 65)
Query Neighborhood Hits	188	Target Neighborhood Hits	94	Shared Neighborhood Hits	25
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

UBP43_MOUSE
θ value	5.79196e-23 (rank : 20)	NC score	0.703962 (rank : 16)
Query Neighborhood Hits	188	Target Neighborhood Hits	130	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP50_MOUSE
θ value	1.42661e-21 (rank : 21)	NC score	0.712307 (rank : 13)
Query Neighborhood Hits	188	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP31_HUMAN
θ value	3.17815e-21 (rank : 22)	NC score	0.686880 (rank : 20)
Query Neighborhood Hits	188	Target Neighborhood Hits	293	Shared Neighborhood Hits	81
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP3_MOUSE
θ value	1.74391e-19 (rank : 23)	NC score	0.695908 (rank : 17)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP22_MOUSE
θ value	6.62687e-19 (rank : 24)	NC score	0.671982 (rank : 24)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP50_HUMAN
θ value	8.65492e-19 (rank : 25)	NC score	0.711702 (rank : 14)
Query Neighborhood Hits	188	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP22_HUMAN
θ value	1.13037e-18 (rank : 26)	NC score	0.671175 (rank : 25)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP20_HUMAN
θ value	3.63628e-17 (rank : 27)	NC score	0.672407 (rank : 23)
Query Neighborhood Hits	188	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP16_HUMAN
θ value	8.10077e-17 (rank : 28)	NC score	0.688422 (rank : 19)
Query Neighborhood Hits	188	Target Neighborhood Hits	126	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP33_HUMAN
θ value	1.80466e-16 (rank : 29)	NC score	0.672412 (rank : 22)
Query Neighborhood Hits	188	Target Neighborhood Hits	157	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

TBCD2_HUMAN
θ value	4.02038e-16 (rank : 30)	NC score	0.350123 (rank : 82)
Query Neighborhood Hits	188	Target Neighborhood Hits	419	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

UBP51_HUMAN
θ value	2.88119e-14 (rank : 31)	NC score	0.662983 (rank : 26)
Query Neighborhood Hits	188	Target Neighborhood Hits	162	Shared Neighborhood Hits	76
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP3_HUMAN
θ value	3.76295e-14 (rank : 32)	NC score	0.685910 (rank : 21)
Query Neighborhood Hits	188	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP44_HUMAN
θ value	6.41864e-14 (rank : 33)	NC score	0.635579 (rank : 28)
Query Neighborhood Hits	188	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

TBCD1_HUMAN
θ value	1.09485e-13 (rank : 34)	NC score	0.358445 (rank : 80)
Query Neighborhood Hits	188	Target Neighborhood Hits	276	Shared Neighborhood Hits	22
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

TBCD4_MOUSE
θ value	1.42992e-13 (rank : 35)	NC score	0.347136 (rank : 83)
Query Neighborhood Hits	188	Target Neighborhood Hits	276	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD1_MOUSE
θ value	1.86753e-13 (rank : 36)	NC score	0.355338 (rank : 81)
Query Neighborhood Hits	188	Target Neighborhood Hits	241	Shared Neighborhood Hits	21
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

TBCD8_MOUSE
θ value	1.86753e-13 (rank : 37)	NC score	0.379906 (rank : 74)
Query Neighborhood Hits	188	Target Neighborhood Hits	64	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z1A9	Gene names	Tbc1d8, Hblp1, Vrp
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (BUB2-like protein 1).

UBP49_MOUSE
θ value	2.43908e-13 (rank : 38)	NC score	0.626073 (rank : 29)
Query Neighborhood Hits	188	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_HUMAN
θ value	4.16044e-13 (rank : 39)	NC score	0.623561 (rank : 30)
Query Neighborhood Hits	188	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

TBCD4_HUMAN
θ value	5.43371e-13 (rank : 40)	NC score	0.340098 (rank : 84)
Query Neighborhood Hits	188	Target Neighborhood Hits	357	Shared Neighborhood Hits	24
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD8_HUMAN
θ value	7.09661e-13 (rank : 41)	NC score	0.374621 (rank : 77)
Query Neighborhood Hits	188	Target Neighborhood Hits	65	Shared Neighborhood Hits	19
SwissProt Accessions	O95759, Q9UQ32	Gene names	TBC1D8, VRP
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (AD 3).

UBP36_HUMAN
θ value	7.09661e-13 (rank : 42)	NC score	0.611140 (rank : 32)
Query Neighborhood Hits	188	Target Neighborhood Hits	232	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

TBC14_HUMAN
θ value	1.58096e-12 (rank : 43)	NC score	0.369346 (rank : 78)
Query Neighborhood Hits	188	Target Neighborhood Hits	124	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

TBC14_MOUSE
θ value	1.58096e-12 (rank : 44)	NC score	0.366495 (rank : 79)
Query Neighborhood Hits	188	Target Neighborhood Hits	135	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CGA2, Q8CHA5	Gene names	Tbc1d14, D5Ertd110e, Kiaa1322
Domain Architecture
Description	TBC1 domain family member 14.

UBPW_MOUSE
θ value	1.58096e-12 (rank : 45)	NC score	0.639203 (rank : 27)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP42_HUMAN
θ value	7.84624e-12 (rank : 46)	NC score	0.593685 (rank : 38)
Query Neighborhood Hits	188	Target Neighborhood Hits	445	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

TBC12_HUMAN
θ value	2.98157e-11 (rank : 47)	NC score	0.375284 (rank : 75)
Query Neighborhood Hits	188	Target Neighborhood Hits	80	Shared Neighborhood Hits	20
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

TBC16_HUMAN
θ value	1.25267e-09 (rank : 48)	NC score	0.279920 (rank : 87)
Query Neighborhood Hits	188	Target Neighborhood Hits	55	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TBP0	Gene names	TBC1D16
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 16.

UBP38_HUMAN
θ value	1.25267e-09 (rank : 49)	NC score	0.525345 (rank : 44)
Query Neighborhood Hits	188	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP12_HUMAN
θ value	1.63604e-09 (rank : 50)	NC score	0.614366 (rank : 31)
Query Neighborhood Hits	188	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP38_MOUSE
θ value	1.63604e-09 (rank : 51)	NC score	0.525206 (rank : 45)
Query Neighborhood Hits	188	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP37_HUMAN
θ value	2.79066e-09 (rank : 52)	NC score	0.533082 (rank : 41)
Query Neighborhood Hits	188	Target Neighborhood Hits	208	Shared Neighborhood Hits	73
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP26_HUMAN
θ value	3.64472e-09 (rank : 53)	NC score	0.482746 (rank : 55)
Query Neighborhood Hits	188	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UB17L_HUMAN
θ value	4.76016e-09 (rank : 54)	NC score	0.608878 (rank : 33)
Query Neighborhood Hits	188	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP29_HUMAN
θ value	3.08544e-08 (rank : 55)	NC score	0.489459 (rank : 53)
Query Neighborhood Hits	188	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP46_HUMAN
θ value	4.0297e-08 (rank : 56)	NC score	0.604222 (rank : 34)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	4.0297e-08 (rank : 57)	NC score	0.604222 (rank : 35)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP30_HUMAN
θ value	8.97725e-08 (rank : 58)	NC score	0.602831 (rank : 37)
Query Neighborhood Hits	188	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP35_HUMAN
θ value	9.92553e-07 (rank : 59)	NC score	0.527848 (rank : 43)
Query Neighborhood Hits	188	Target Neighborhood Hits	223	Shared Neighborhood Hits	71
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP29_MOUSE
θ value	3.19293e-05 (rank : 60)	NC score	0.456763 (rank : 62)
Query Neighborhood Hits	188	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP18_MOUSE
θ value	4.1701e-05 (rank : 61)	NC score	0.566565 (rank : 40)
Query Neighborhood Hits	188	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

SNUT2_MOUSE
θ value	5.44631e-05 (rank : 62)	NC score	0.529075 (rank : 42)
Query Neighborhood Hits	188	Target Neighborhood Hits	80	Shared Neighborhood Hits	61
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

SNUT2_HUMAN
θ value	7.1131e-05 (rank : 63)	NC score	0.523331 (rank : 46)
Query Neighborhood Hits	188	Target Neighborhood Hits	79	Shared Neighborhood Hits	59
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP14_HUMAN
θ value	7.1131e-05 (rank : 64)	NC score	0.476984 (rank : 56)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP14_MOUSE
θ value	0.000158464 (rank : 65)	NC score	0.469532 (rank : 58)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP28_HUMAN
θ value	0.000158464 (rank : 66)	NC score	0.299185 (rank : 85)
Query Neighborhood Hits	188	Target Neighborhood Hits	117	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP18_HUMAN
θ value	0.000270298 (rank : 67)	NC score	0.571699 (rank : 39)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP47_HUMAN
θ value	0.00035302 (rank : 68)	NC score	0.459603 (rank : 61)
Query Neighborhood Hits	188	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP24_HUMAN
θ value	0.000461057 (rank : 69)	NC score	0.473679 (rank : 57)
Query Neighborhood Hits	188	Target Neighborhood Hits	96	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP47_MOUSE
θ value	0.000461057 (rank : 70)	NC score	0.465682 (rank : 60)
Query Neighborhood Hits	188	Target Neighborhood Hits	135	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP5_HUMAN
θ value	0.000461057 (rank : 71)	NC score	0.406351 (rank : 68)
Query Neighborhood Hits	188	Target Neighborhood Hits	109	Shared Neighborhood Hits	74
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
θ value	0.00175202 (rank : 72)	NC score	0.400935 (rank : 70)
Query Neighborhood Hits	188	Target Neighborhood Hits	106	Shared Neighborhood Hits	74
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP28_MOUSE
θ value	0.00228821 (rank : 73)	NC score	0.294484 (rank : 86)
Query Neighborhood Hits	188	Target Neighborhood Hits	178	Shared Neighborhood Hits	79
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP1_HUMAN
θ value	0.00390308 (rank : 74)	NC score	0.516146 (rank : 50)
Query Neighborhood Hits	188	Target Neighborhood Hits	259	Shared Neighborhood Hits	75
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP48_HUMAN
θ value	0.00390308 (rank : 75)	NC score	0.520288 (rank : 48)
Query Neighborhood Hits	188	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
θ value	0.00390308 (rank : 76)	NC score	0.517281 (rank : 49)
Query Neighborhood Hits	188	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP13_HUMAN
θ value	0.00665767 (rank : 77)	NC score	0.404638 (rank : 69)
Query Neighborhood Hits	188	Target Neighborhood Hits	99	Shared Neighborhood Hits	73
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

KCNK4_HUMAN
θ value	0.0113563 (rank : 78)	NC score	0.023478 (rank : 124)
Query Neighborhood Hits	188	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

USP9X_HUMAN
θ value	0.0193708 (rank : 79)	NC score	0.398476 (rank : 71)
Query Neighborhood Hits	188	Target Neighborhood Hits	161	Shared Neighborhood Hits	76
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
θ value	0.0193708 (rank : 80)	NC score	0.397872 (rank : 72)
Query Neighborhood Hits	188	Target Neighborhood Hits	171	Shared Neighborhood Hits	78
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP40_HUMAN
θ value	0.0252991 (rank : 81)	NC score	0.467728 (rank : 59)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

USP9Y_HUMAN
θ value	0.0252991 (rank : 82)	NC score	0.394639 (rank : 73)
Query Neighborhood Hits	188	Target Neighborhood Hits	109	Shared Neighborhood Hits	75
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

RIN2_HUMAN
θ value	0.0431538 (rank : 83)	NC score	0.028751 (rank : 115)
Query Neighborhood Hits	188	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

UBP25_HUMAN
θ value	0.0563607 (rank : 84)	NC score	0.265719 (rank : 89)
Query Neighborhood Hits	188	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP25_MOUSE
θ value	0.0563607 (rank : 85)	NC score	0.266938 (rank : 88)
Query Neighborhood Hits	188	Target Neighborhood Hits	116	Shared Neighborhood Hits	73
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP26_MOUSE
θ value	0.0563607 (rank : 86)	NC score	0.374880 (rank : 76)
Query Neighborhood Hits	188	Target Neighborhood Hits	107	Shared Neighborhood Hits	71
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP34_MOUSE
θ value	0.0563607 (rank : 87)	NC score	0.407430 (rank : 66)
Query Neighborhood Hits	188	Target Neighborhood Hits	189	Shared Neighborhood Hits	70
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP7_HUMAN
θ value	0.0563607 (rank : 88)	NC score	0.454129 (rank : 63)
Query Neighborhood Hits	188	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

TBC17_MOUSE
θ value	0.0736092 (rank : 89)	NC score	0.164648 (rank : 90)
Query Neighborhood Hits	188	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BYH7	Gene names	Tbc1d17
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 17.

TBC20_HUMAN
θ value	0.0736092 (rank : 90)	NC score	0.073670 (rank : 101)
Query Neighborhood Hits	188	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q96BZ9, Q5JWQ7, Q96NE1, Q9BYM7, Q9H140	Gene names	TBC1D20, C20orf140
Domain Architecture
Description	TBC1 domain family member 20.

UBP10_MOUSE
θ value	0.0736092 (rank : 91)	NC score	0.496556 (rank : 52)
Query Neighborhood Hits	188	Target Neighborhood Hits	150	Shared Neighborhood Hits	73
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP34_HUMAN
θ value	0.0736092 (rank : 92)	NC score	0.407332 (rank : 67)
Query Neighborhood Hits	188	Target Neighborhood Hits	210	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

WDR33_HUMAN
θ value	0.125558 (rank : 93)	NC score	0.008746 (rank : 168)
Query Neighborhood Hits	188	Target Neighborhood Hits	638	Shared Neighborhood Hits	17
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

TBC17_HUMAN
θ value	0.163984 (rank : 94)	NC score	0.159318 (rank : 91)
Query Neighborhood Hits	188	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HA65	Gene names	TBC1D17
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 17.

UBP10_HUMAN
θ value	0.21417 (rank : 95)	NC score	0.487835 (rank : 54)
Query Neighborhood Hits	188	Target Neighborhood Hits	153	Shared Neighborhood Hits	72
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

TBC20_MOUSE
θ value	0.279714 (rank : 96)	NC score	0.069088 (rank : 102)
Query Neighborhood Hits	188	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D9I4, Q3TYW9, Q99LW2	Gene names	Tbc1d20
Domain Architecture
Description	TBC1 domain family member 20.

CF064_HUMAN
θ value	0.365318 (rank : 97)	NC score	0.040946 (rank : 108)
Query Neighborhood Hits	188	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPB0, Q9H0D8	Gene names	C6orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf64.

TRIP6_HUMAN
θ value	0.365318 (rank : 98)	NC score	0.015504 (rank : 135)
Query Neighborhood Hits	188	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

ADA19_HUMAN
θ value	0.47712 (rank : 99)	NC score	0.005850 (rank : 183)
Query Neighborhood Hits	188	Target Neighborhood Hits	381	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

SGIP1_HUMAN
θ value	0.47712 (rank : 100)	NC score	0.026626 (rank : 118)
Query Neighborhood Hits	188	Target Neighborhood Hits	198	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SRRM1_HUMAN
θ value	0.47712 (rank : 101)	NC score	0.034359 (rank : 109)
Query Neighborhood Hits	188	Target Neighborhood Hits	690	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

WNK2_HUMAN
θ value	0.47712 (rank : 102)	NC score	0.000407 (rank : 193)
Query Neighborhood Hits	188	Target Neighborhood Hits	1407	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ICA69_MOUSE
θ value	0.62314 (rank : 103)	NC score	0.018107 (rank : 132)
Query Neighborhood Hits	188	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P97411, P97362, P97954, Q99M40, Q9R2C4	Gene names	Ica1, Icap69
Domain Architecture	No domain graphic available
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

PRC1_MOUSE
θ value	0.62314 (rank : 104)	NC score	0.014645 (rank : 141)
Query Neighborhood Hits	188	Target Neighborhood Hits	382	Shared Neighborhood Hits	7
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

ZYX_HUMAN
θ value	0.813845 (rank : 105)	NC score	0.013177 (rank : 144)
Query Neighborhood Hits	188	Target Neighborhood Hits	387	Shared Neighborhood Hits	14
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

CO3A1_HUMAN
θ value	1.06291 (rank : 106)	NC score	0.006559 (rank : 176)
Query Neighborhood Hits	188	Target Neighborhood Hits	452	Shared Neighborhood Hits	19
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

COIA1_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.008295 (rank : 170)
Query Neighborhood Hits	188	Target Neighborhood Hits	447	Shared Neighborhood Hits	19
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

LCP2_HUMAN
θ value	1.06291 (rank : 108)	NC score	0.025261 (rank : 122)
Query Neighborhood Hits	188	Target Neighborhood Hits	531	Shared Neighborhood Hits	30
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MEF2B_HUMAN
θ value	1.06291 (rank : 109)	NC score	0.015339 (rank : 137)
Query Neighborhood Hits	188	Target Neighborhood Hits	150	Shared Neighborhood Hits	12
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

NCOA6_HUMAN
θ value	1.06291 (rank : 110)	NC score	0.026201 (rank : 119)
Query Neighborhood Hits	188	Target Neighborhood Hits	1202	Shared Neighborhood Hits	56
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	1.06291 (rank : 111)	NC score	0.031127 (rank : 111)
Query Neighborhood Hits	188	Target Neighborhood Hits	1076	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NFAC4_HUMAN
θ value	1.06291 (rank : 112)	NC score	0.012731 (rank : 147)
Query Neighborhood Hits	188	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

PRRT1_MOUSE
θ value	1.06291 (rank : 113)	NC score	0.028828 (rank : 114)
Query Neighborhood Hits	188	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

ARI1B_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.029425 (rank : 113)
Query Neighborhood Hits	188	Target Neighborhood Hits	567	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CN032_HUMAN
θ value	1.38821 (rank : 115)	NC score	0.021677 (rank : 125)
Query Neighborhood Hits	188	Target Neighborhood Hits	267	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

NMDE4_MOUSE
θ value	1.38821 (rank : 116)	NC score	0.005878 (rank : 182)
Query Neighborhood Hits	188	Target Neighborhood Hits	158	Shared Neighborhood Hits	8
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

SRRM1_MOUSE
θ value	1.38821 (rank : 117)	NC score	0.034332 (rank : 110)
Query Neighborhood Hits	188	Target Neighborhood Hits	966	Shared Neighborhood Hits	48
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TEX15_HUMAN
θ value	1.38821 (rank : 118)	NC score	0.030473 (rank : 112)
Query Neighborhood Hits	188	Target Neighborhood Hits	174	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

DBF4_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.019638 (rank : 129)
Query Neighborhood Hits	188	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBU7, O75226, Q75MS6, Q75N01, Q9Y2M6	Gene names	DBF4, ASK
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (Activator of S phase Kinase).

HCN2_HUMAN
θ value	1.81305 (rank : 120)	NC score	0.011283 (rank : 153)
Query Neighborhood Hits	188	Target Neighborhood Hits	369	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HXC10_HUMAN
θ value	1.81305 (rank : 121)	NC score	0.004091 (rank : 186)
Query Neighborhood Hits	188	Target Neighborhood Hits	417	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYD6, O15219, O15220, Q9BVD5	Gene names	HOXC10
Domain Architecture
Description	Homeobox protein Hox-C10.

LPXN_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.009835 (rank : 160)
Query Neighborhood Hits	188	Target Neighborhood Hits	159	Shared Neighborhood Hits	5
SwissProt Accessions	O60711	Gene names	LPXN, LDLP
Domain Architecture
Description	Leupaxin.

LPXN_MOUSE
θ value	1.81305 (rank : 123)	NC score	0.009420 (rank : 163)
Query Neighborhood Hits	188	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

MLL4_HUMAN
θ value	1.81305 (rank : 124)	NC score	0.014975 (rank : 139)
Query Neighborhood Hits	188	Target Neighborhood Hits	722	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

TAF6_MOUSE
θ value	1.81305 (rank : 125)	NC score	0.015078 (rank : 138)
Query Neighborhood Hits	188	Target Neighborhood Hits	110	Shared Neighborhood Hits	9
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

WASL_HUMAN
θ value	1.81305 (rank : 126)	NC score	0.025273 (rank : 121)
Query Neighborhood Hits	188	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASP_HUMAN
θ value	1.81305 (rank : 127)	NC score	0.027287 (rank : 117)
Query Neighborhood Hits	188	Target Neighborhood Hits	195	Shared Neighborhood Hits	19
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

WASP_MOUSE
θ value	1.81305 (rank : 128)	NC score	0.025313 (rank : 120)
Query Neighborhood Hits	188	Target Neighborhood Hits	223	Shared Neighborhood Hits	18
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

ZN648_HUMAN
θ value	1.81305 (rank : 129)	NC score	-0.004806 (rank : 199)
Query Neighborhood Hits	188	Target Neighborhood Hits	751	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T619	Gene names	ZNF648
Domain Architecture	No domain graphic available
Description	Zinc finger protein 648.

CN032_MOUSE
θ value	2.36792 (rank : 130)	NC score	0.019934 (rank : 128)
Query Neighborhood Hits	188	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

HCN4_MOUSE
θ value	2.36792 (rank : 131)	NC score	0.011648 (rank : 152)
Query Neighborhood Hits	188	Target Neighborhood Hits	284	Shared Neighborhood Hits	16
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

IRX2_HUMAN
θ value	2.36792 (rank : 132)	NC score	0.006226 (rank : 180)
Query Neighborhood Hits	188	Target Neighborhood Hits	358	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

NACAM_MOUSE
θ value	2.36792 (rank : 133)	NC score	0.020590 (rank : 126)
Query Neighborhood Hits	188	Target Neighborhood Hits	1866	Shared Neighborhood Hits	67
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RIF1_HUMAN
θ value	2.36792 (rank : 134)	NC score	0.015586 (rank : 134)
Query Neighborhood Hits	188	Target Neighborhood Hits	320	Shared Neighborhood Hits	5
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

SEM6C_MOUSE
θ value	2.36792 (rank : 135)	NC score	0.005343 (rank : 185)
Query Neighborhood Hits	188	Target Neighborhood Hits	352	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

ATX2_MOUSE
θ value	3.0926 (rank : 136)	NC score	0.012509 (rank : 149)
Query Neighborhood Hits	188	Target Neighborhood Hits	445	Shared Neighborhood Hits	31
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CRTC1_HUMAN
θ value	3.0926 (rank : 137)	NC score	0.012855 (rank : 145)
Query Neighborhood Hits	188	Target Neighborhood Hits	319	Shared Neighborhood Hits	18
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

HCN2_MOUSE
θ value	3.0926 (rank : 138)	NC score	0.010013 (rank : 158)
Query Neighborhood Hits	188	Target Neighborhood Hits	278	Shared Neighborhood Hits	12
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

PRP1_HUMAN
θ value	3.0926 (rank : 139)	NC score	0.020272 (rank : 127)
Query Neighborhood Hits	188	Target Neighborhood Hits	385	Shared Neighborhood Hits	24
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRRT1_HUMAN
θ value	3.0926 (rank : 140)	NC score	0.024945 (rank : 123)
Query Neighborhood Hits	188	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

SNX18_HUMAN
θ value	3.0926 (rank : 141)	NC score	0.006948 (rank : 175)
Query Neighborhood Hits	188	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

TCF20_HUMAN
θ value	3.0926 (rank : 142)	NC score	0.014629 (rank : 142)
Query Neighborhood Hits	188	Target Neighborhood Hits	323	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

WASIP_HUMAN
θ value	3.0926 (rank : 143)	NC score	0.018658 (rank : 131)
Query Neighborhood Hits	188	Target Neighborhood Hits	458	Shared Neighborhood Hits	23
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ARI1A_HUMAN
θ value	4.03905 (rank : 144)	NC score	0.028044 (rank : 116)
Query Neighborhood Hits	188	Target Neighborhood Hits	787	Shared Neighborhood Hits	40
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ASPP1_HUMAN
θ value	4.03905 (rank : 145)	NC score	0.006297 (rank : 179)
Query Neighborhood Hits	188	Target Neighborhood Hits	956	Shared Neighborhood Hits	24
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PELP1_MOUSE
θ value	4.03905 (rank : 146)	NC score	0.010793 (rank : 155)
Query Neighborhood Hits	188	Target Neighborhood Hits	709	Shared Neighborhood Hits	32
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SFPQ_HUMAN
θ value	4.03905 (rank : 147)	NC score	0.005647 (rank : 184)
Query Neighborhood Hits	188	Target Neighborhood Hits	986	Shared Neighborhood Hits	22
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

APEH_MOUSE
θ value	5.27518 (rank : 148)	NC score	0.012836 (rank : 146)
Query Neighborhood Hits	188	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R146, Q8K029, Q8R0M9	Gene names	Apeh
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase).

CBP_MOUSE
θ value	5.27518 (rank : 149)	NC score	0.010522 (rank : 156)
Query Neighborhood Hits	188	Target Neighborhood Hits	1051	Shared Neighborhood Hits	47
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

FANCJ_MOUSE
θ value	5.27518 (rank : 150)	NC score	0.007933 (rank : 172)
Query Neighborhood Hits	188	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SXJ3, Q8BJQ8, Q8BKI6	Gene names	Brip1, Bach1, Fancj
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

ITSN1_HUMAN
θ value	5.27518 (rank : 151)	NC score	0.000873 (rank : 191)
Query Neighborhood Hits	188	Target Neighborhood Hits	1757	Shared Neighborhood Hits	36
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

NKX61_HUMAN
θ value	5.27518 (rank : 152)	NC score	-0.000241 (rank : 194)
Query Neighborhood Hits	188	Target Neighborhood Hits	431	Shared Neighborhood Hits	10
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

PLS1_HUMAN
θ value	5.27518 (rank : 153)	NC score	0.008774 (rank : 167)
Query Neighborhood Hits	188	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	O15162	Gene names	PLSCR1
Domain Architecture
Description	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b).

PROP1_HUMAN
θ value	5.27518 (rank : 154)	NC score	-0.000604 (rank : 196)
Query Neighborhood Hits	188	Target Neighborhood Hits	354	Shared Neighborhood Hits	5
SwissProt Accessions	O75360	Gene names	PROP1
Domain Architecture
Description	Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor).

RAI1_HUMAN
θ value	5.27518 (rank : 155)	NC score	0.016770 (rank : 133)
Query Neighborhood Hits	188	Target Neighborhood Hits	360	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SAM68_MOUSE
θ value	5.27518 (rank : 156)	NC score	0.009581 (rank : 161)
Query Neighborhood Hits	188	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SRTD2_MOUSE
θ value	5.27518 (rank : 157)	NC score	0.010895 (rank : 154)
Query Neighborhood Hits	188	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJG5, Q8C609, Q91WL3, Q925E5	Gene names	Sertad2, Kiaa0127
Domain Architecture
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

SYN1_MOUSE
θ value	5.27518 (rank : 158)	NC score	0.012145 (rank : 150)
Query Neighborhood Hits	188	Target Neighborhood Hits	363	Shared Neighborhood Hits	24
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TS101_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.007269 (rank : 174)
Query Neighborhood Hits	188	Target Neighborhood Hits	359	Shared Neighborhood Hits	6
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

CAC1E_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.001510 (rank : 190)
Query Neighborhood Hits	188	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CATW_HUMAN
θ value	6.88961 (rank : 161)	NC score	0.003670 (rank : 187)
Query Neighborhood Hits	188	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P56202, Q86VT4	Gene names	CTSW
Domain Architecture
Description	Cathepsin W precursor (EC 3.4.22.-) (Lymphopain).

CSKI2_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.002509 (rank : 189)
Query Neighborhood Hits	188	Target Neighborhood Hits	747	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

GP133_HUMAN
θ value	6.88961 (rank : 163)	NC score	0.000575 (rank : 192)
Query Neighborhood Hits	188	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

PDC6I_MOUSE
θ value	6.88961 (rank : 164)	NC score	0.006358 (rank : 177)
Query Neighborhood Hits	188	Target Neighborhood Hits	275	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PLS1_MOUSE
θ value	6.88961 (rank : 165)	NC score	0.007659 (rank : 173)
Query Neighborhood Hits	188	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JJ00, O54730, O54731, Q9D1F8	Gene names	Plscr1, Tra1b, Tras1
Domain Architecture
Description	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Transplantability-associated protein 1) (TRA1) (NOR1).

RD23B_HUMAN
θ value	6.88961 (rank : 166)	NC score	0.014853 (rank : 140)
Query Neighborhood Hits	188	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

RIN3_HUMAN
θ value	6.88961 (rank : 167)	NC score	0.013875 (rank : 143)
Query Neighborhood Hits	188	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SPEG_HUMAN
θ value	6.88961 (rank : 168)	NC score	-0.003307 (rank : 197)
Query Neighborhood Hits	188	Target Neighborhood Hits	1762	Shared Neighborhood Hits	33
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SYNJ1_HUMAN
θ value	6.88961 (rank : 169)	NC score	0.010032 (rank : 157)
Query Neighborhood Hits	188	Target Neighborhood Hits	498	Shared Neighborhood Hits	24
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TBCEL_HUMAN
θ value	6.88961 (rank : 170)	NC score	0.009359 (rank : 164)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q5QJ74	Gene names	LRRC35
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35).

TISD_HUMAN
θ value	6.88961 (rank : 171)	NC score	0.006324 (rank : 178)
Query Neighborhood Hits	188	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P47974, Q9BSJ3	Gene names	ZFP36L2, BRF2, ERF2, TIS11D
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein) (EGF-response factor 2) (ERF-2).

TNK1_HUMAN
θ value	6.88961 (rank : 172)	NC score	-0.005402 (rank : 200)
Query Neighborhood Hits	188	Target Neighborhood Hits	815	Shared Neighborhood Hits	9
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

ULK1_HUMAN
θ value	6.88961 (rank : 173)	NC score	-0.006019 (rank : 201)
Query Neighborhood Hits	188	Target Neighborhood Hits	1121	Shared Neighborhood Hits	25
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ZN318_MOUSE
θ value	6.88961 (rank : 174)	NC score	0.011936 (rank : 151)
Query Neighborhood Hits	188	Target Neighborhood Hits	642	Shared Neighborhood Hits	19
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

BSN_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.012621 (rank : 148)
Query Neighborhood Hits	188	Target Neighborhood Hits	2057	Shared Neighborhood Hits	66
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CECR6_MOUSE
θ value	8.99809 (rank : 176)	NC score	0.008144 (rank : 171)
Query Neighborhood Hits	188	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MX7	Gene names	Cecr6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6 homolog.

DAAM1_MOUSE
θ value	8.99809 (rank : 177)	NC score	0.002710 (rank : 188)
Query Neighborhood Hits	188	Target Neighborhood Hits	443	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DC1L2_MOUSE
θ value	8.99809 (rank : 178)	NC score	0.009844 (rank : 159)
Query Neighborhood Hits	188	Target Neighborhood Hits	173	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

EVI1_MOUSE
θ value	8.99809 (rank : 179)	NC score	-0.006658 (rank : 202)
Query Neighborhood Hits	188	Target Neighborhood Hits	826	Shared Neighborhood Hits	5
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

PER3_HUMAN
θ value	8.99809 (rank : 180)	NC score	0.009260 (rank : 165)
Query Neighborhood Hits	188	Target Neighborhood Hits	479	Shared Neighborhood Hits	34
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

SETBP_MOUSE
θ value	8.99809 (rank : 181)	NC score	0.006183 (rank : 181)
Query Neighborhood Hits	188	Target Neighborhood Hits	352	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SF01_HUMAN
θ value	8.99809 (rank : 182)	NC score	0.009226 (rank : 166)
Query Neighborhood Hits	188	Target Neighborhood Hits	287	Shared Neighborhood Hits	18
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

STF1_MOUSE
θ value	8.99809 (rank : 183)	NC score	-0.000246 (rank : 195)
Query Neighborhood Hits	188	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

STK10_HUMAN
θ value	8.99809 (rank : 184)	NC score	-0.003881 (rank : 198)
Query Neighborhood Hits	188	Target Neighborhood Hits	1921	Shared Neighborhood Hits	30
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TBCEL_MOUSE
θ value	8.99809 (rank : 185)	NC score	0.008611 (rank : 169)
Query Neighborhood Hits	188	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C5W3, Q8C7A5	Gene names	Lrrc35
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35).

TCF20_MOUSE
θ value	8.99809 (rank : 186)	NC score	0.015351 (rank : 136)
Query Neighborhood Hits	188	Target Neighborhood Hits	396	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

WASL_MOUSE
θ value	8.99809 (rank : 187)	NC score	0.019122 (rank : 130)
Query Neighborhood Hits	188	Target Neighborhood Hits	339	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

YLPM1_MOUSE
θ value	8.99809 (rank : 188)	NC score	0.009489 (rank : 162)
Query Neighborhood Hits	188	Target Neighborhood Hits	505	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

BRAP_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.067739 (rank : 103)
Query Neighborhood Hits	188	Target Neighborhood Hits	560	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.078055 (rank : 99)
Query Neighborhood Hits	188	Target Neighborhood Hits	409	Shared Neighborhood Hits	16
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

GGNB1_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.106946 (rank : 95)
Query Neighborhood Hits	188	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5YKI7, Q5YKI8	Gene names	GGNBP1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

GGNB1_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.146623 (rank : 94)
Query Neighborhood Hits	188	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

HDAC6_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.052723 (rank : 106)
Query Neighborhood Hits	188	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

TB22A_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.096361 (rank : 98)
Query Neighborhood Hits	188	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WUA7, Q5TE47, Q6ZUH2, Q92680, Q9BVD6, Q9UGG0, Q9UGT2, Q9UGU6, Q9UH25, Q9Y4W5	Gene names	TBC1D22A, C22orf4
Domain Architecture
Description	TBC1 domain family member 22A.

TB22A_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.097590 (rank : 97)
Query Neighborhood Hits	188	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R5A6, Q3U268, Q3U3T0, Q8CA49	Gene names	Tbc1d22a, D15Ertd781e
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 22A.

TB22B_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.104201 (rank : 96)
Query Neighborhood Hits	188	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NU19, Q5VUK9, Q7Z6P7, Q9BPV6, Q9BUT5, Q9NXB6	Gene names	TBC1D22B, C6orf197
Domain Architecture
Description	TBC1 domain family member 22B.

TBC13_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.075255 (rank : 100)
Query Neighborhood Hits	188	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R3D1	Gene names	Tbc1d13
Domain Architecture
Description	TBC1 domain family member 13.

TBC15_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.150176 (rank : 93)
Query Neighborhood Hits	188	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TC07	Gene names	TBC1D15
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 15.

TBC15_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.153349 (rank : 92)
Query Neighborhood Hits	188	Target Neighborhood Hits	40	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CXF4, Q3UI41	Gene names	Tbc1d15
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 15.

TBCD5_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.064309 (rank : 104)
Query Neighborhood Hits	188	Target Neighborhood Hits	70	Shared Neighborhood Hits	18
SwissProt Accessions	Q92609	Gene names	TBC1D5, KIAA0210
Domain Architecture
Description	TBC1 domain family member 5.

TBCD5_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.055797 (rank : 105)
Query Neighborhood Hits	188	Target Neighborhood Hits	71	Shared Neighborhood Hits	17
SwissProt Accessions	Q80XQ2	Gene names	Tbc1d5
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 5.

TBCD7_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.052702 (rank : 107)
Query Neighborhood Hits	188	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D0K0, Q3U0V0	Gene names	Tbc1d7
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 7.

Hits sorted by NC score

UBP6_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	188	Target Neighborhood Hits	188	Shared Neighborhood Hits	188
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP32_HUMAN
NC score	0.798173 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	188	Target Neighborhood Hits	170	Shared Neighborhood Hits	82
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP11_HUMAN
NC score	0.793764 (rank : 3)	θ value	1.11475e-66 (rank : 10)
Query Neighborhood Hits	188	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP4_HUMAN
NC score	0.788528 (rank : 4)	θ value	4.52582e-68 (rank : 8)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP4_MOUSE
NC score	0.788271 (rank : 5)	θ value	1.71981e-67 (rank : 9)
Query Neighborhood Hits	188	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP15_MOUSE
NC score	0.785772 (rank : 6)	θ value	6.31527e-70 (rank : 7)
Query Neighborhood Hits	188	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP15_HUMAN
NC score	0.785633 (rank : 7)	θ value	9.74306e-71 (rank : 5)
Query Neighborhood Hits	188	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP2_MOUSE
NC score	0.744957 (rank : 8)	θ value	2.42216e-37 (rank : 13)
Query Neighborhood Hits	188	Target Neighborhood Hits	86	Shared Neighborhood Hits	74
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_HUMAN
NC score	0.742674 (rank : 9)	θ value	7.04741e-37 (rank : 14)
Query Neighborhood Hits	188	Target Neighborhood Hits	84	Shared Neighborhood Hits	73
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP21_MOUSE
NC score	0.727644 (rank : 10)	θ value	1.73987e-27 (rank : 15)
Query Neighborhood Hits	188	Target Neighborhood Hits	101	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP8_MOUSE
NC score	0.725560 (rank : 11)	θ value	6.81017e-40 (rank : 12)
Query Neighborhood Hits	188	Target Neighborhood Hits	362	Shared Neighborhood Hits	78
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP21_HUMAN
NC score	0.725054 (rank : 12)	θ value	2.51237e-26 (rank : 16)
Query Neighborhood Hits	188	Target Neighborhood Hits	95	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP50_MOUSE
NC score	0.712307 (rank : 13)	θ value	1.42661e-21 (rank : 21)
Query Neighborhood Hits	188	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP50_HUMAN
NC score	0.711702 (rank : 14)	θ value	8.65492e-19 (rank : 25)
Query Neighborhood Hits	188	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP43_HUMAN
NC score	0.706191 (rank : 15)	θ value	3.07116e-24 (rank : 17)
Query Neighborhood Hits	188	Target Neighborhood Hits	144	Shared Neighborhood Hits	79
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP43_MOUSE
NC score	0.703962 (rank : 16)	θ value	5.79196e-23 (rank : 20)
Query Neighborhood Hits	188	Target Neighborhood Hits	130	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP3_MOUSE
NC score	0.695908 (rank : 17)	θ value	1.74391e-19 (rank : 23)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP8_HUMAN
NC score	0.692183 (rank : 18)	θ value	2.11701e-41 (rank : 11)
Query Neighborhood Hits	188	Target Neighborhood Hits	751	Shared Neighborhood Hits	81
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP16_HUMAN
NC score	0.688422 (rank : 19)	θ value	8.10077e-17 (rank : 28)
Query Neighborhood Hits	188	Target Neighborhood Hits	126	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP31_HUMAN
NC score	0.686880 (rank : 20)	θ value	3.17815e-21 (rank : 22)
Query Neighborhood Hits	188	Target Neighborhood Hits	293	Shared Neighborhood Hits	81
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP3_HUMAN
NC score	0.685910 (rank : 21)	θ value	3.76295e-14 (rank : 32)
Query Neighborhood Hits	188	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP33_HUMAN
NC score	0.672412 (rank : 22)	θ value	1.80466e-16 (rank : 29)
Query Neighborhood Hits	188	Target Neighborhood Hits	157	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP20_HUMAN
NC score	0.672407 (rank : 23)	θ value	3.63628e-17 (rank : 27)
Query Neighborhood Hits	188	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP22_MOUSE
NC score	0.671982 (rank : 24)	θ value	6.62687e-19 (rank : 24)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_HUMAN
NC score	0.671175 (rank : 25)	θ value	1.13037e-18 (rank : 26)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
NC score	0.662983 (rank : 26)	θ value	2.88119e-14 (rank : 31)
Query Neighborhood Hits	188	Target Neighborhood Hits	162	Shared Neighborhood Hits	76
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBPW_MOUSE
NC score	0.639203 (rank : 27)	θ value	1.58096e-12 (rank : 45)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP44_HUMAN
NC score	0.635579 (rank : 28)	θ value	6.41864e-14 (rank : 33)
Query Neighborhood Hits	188	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP49_MOUSE
NC score	0.626073 (rank : 29)	θ value	2.43908e-13 (rank : 38)
Query Neighborhood Hits	188	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_HUMAN
NC score	0.623561 (rank : 30)	θ value	4.16044e-13 (rank : 39)
Query Neighborhood Hits	188	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP12_HUMAN
NC score	0.614366 (rank : 31)	θ value	1.63604e-09 (rank : 50)
Query Neighborhood Hits	188	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP36_HUMAN
NC score	0.611140 (rank : 32)	θ value	7.09661e-13 (rank : 42)
Query Neighborhood Hits	188	Target Neighborhood Hits	232	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UB17L_HUMAN
NC score	0.608878 (rank : 33)	θ value	4.76016e-09 (rank : 54)
Query Neighborhood Hits	188	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP46_HUMAN
NC score	0.604222 (rank : 34)	θ value	4.0297e-08 (rank : 56)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.604222 (rank : 35)	θ value	4.0297e-08 (rank : 57)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

TBCD3_HUMAN
NC score	0.603453 (rank : 36)	θ value	0 (rank : 1)
Query Neighborhood Hits	188	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

UBP30_HUMAN
NC score	0.602831 (rank : 37)	θ value	8.97725e-08 (rank : 58)
Query Neighborhood Hits	188	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP42_HUMAN
NC score	0.593685 (rank : 38)	θ value	7.84624e-12 (rank : 46)
Query Neighborhood Hits	188	Target Neighborhood Hits	445	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP18_HUMAN
NC score	0.571699 (rank : 39)	θ value	0.000270298 (rank : 67)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP18_MOUSE
NC score	0.566565 (rank : 40)	θ value	4.1701e-05 (rank : 61)
Query Neighborhood Hits	188	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP37_HUMAN
NC score	0.533082 (rank : 41)	θ value	2.79066e-09 (rank : 52)
Query Neighborhood Hits	188	Target Neighborhood Hits	208	Shared Neighborhood Hits	73
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

SNUT2_MOUSE
NC score	0.529075 (rank : 42)	θ value	5.44631e-05 (rank : 62)
Query Neighborhood Hits	188	Target Neighborhood Hits	80	Shared Neighborhood Hits	61
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBP35_HUMAN
NC score	0.527848 (rank : 43)	θ value	9.92553e-07 (rank : 59)
Query Neighborhood Hits	188	Target Neighborhood Hits	223	Shared Neighborhood Hits	71
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP38_HUMAN
NC score	0.525345 (rank : 44)	θ value	1.25267e-09 (rank : 49)
Query Neighborhood Hits	188	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP38_MOUSE
NC score	0.525206 (rank : 45)	θ value	1.63604e-09 (rank : 51)
Query Neighborhood Hits	188	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

SNUT2_HUMAN
NC score	0.523331 (rank : 46)	θ value	7.1131e-05 (rank : 63)
Query Neighborhood Hits	188	Target Neighborhood Hits	79	Shared Neighborhood Hits	59
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

US6NL_MOUSE
NC score	0.520774 (rank : 47)	θ value	2.09745e-73 (rank : 4)
Query Neighborhood Hits	188	Target Neighborhood Hits	157	Shared Neighborhood Hits	29
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

UBP48_HUMAN
NC score	0.520288 (rank : 48)	θ value	0.00390308 (rank : 75)
Query Neighborhood Hits	188	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
NC score	0.517281 (rank : 49)	θ value	0.00390308 (rank : 76)
Query Neighborhood Hits	188	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP1_HUMAN
NC score	0.516146 (rank : 50)	θ value	0.00390308 (rank : 74)
Query Neighborhood Hits	188	Target Neighborhood Hits	259	Shared Neighborhood Hits	75
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

US6NL_HUMAN
NC score	0.515403 (rank : 51)	θ value	1.66191e-70 (rank : 6)
Query Neighborhood Hits	188	Target Neighborhood Hits	201	Shared Neighborhood Hits	27
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

UBP10_MOUSE
NC score	0.496556 (rank : 52)	θ value	0.0736092 (rank : 91)
Query Neighborhood Hits	188	Target Neighborhood Hits	150	Shared Neighborhood Hits	73
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP29_HUMAN
NC score	0.489459 (rank : 53)	θ value	3.08544e-08 (rank : 55)
Query Neighborhood Hits	188	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP10_HUMAN
NC score	0.487835 (rank : 54)	θ value	0.21417 (rank : 95)
Query Neighborhood Hits	188	Target Neighborhood Hits	153	Shared Neighborhood Hits	72
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP26_HUMAN
NC score	0.482746 (rank : 55)	θ value	3.64472e-09 (rank : 53)
Query Neighborhood Hits	188	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP14_HUMAN
NC score	0.476984 (rank : 56)	θ value	7.1131e-05 (rank : 64)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP24_HUMAN
NC score	0.473679 (rank : 57)	θ value	0.000461057 (rank : 69)
Query Neighborhood Hits	188	Target Neighborhood Hits	96	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP14_MOUSE
NC score	0.469532 (rank : 58)	θ value	0.000158464 (rank : 65)
Query Neighborhood Hits	188	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP40_HUMAN
NC score	0.467728 (rank : 59)	θ value	0.0252991 (rank : 81)
Query Neighborhood Hits	188	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP47_MOUSE
NC score	0.465682 (rank : 60)	θ value	0.000461057 (rank : 70)
Query Neighborhood Hits	188	Target Neighborhood Hits	135	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_HUMAN
NC score	0.459603 (rank : 61)	θ value	0.00035302 (rank : 68)
Query Neighborhood Hits	188	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP29_MOUSE
NC score	0.456763 (rank : 62)	θ value	3.19293e-05 (rank : 60)
Query Neighborhood Hits	188	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP7_HUMAN
NC score	0.454129 (rank : 63)	θ value	0.0563607 (rank : 88)
Query Neighborhood Hits	188	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

TBC10_HUMAN
NC score	0.450629 (rank : 64)	θ value	5.23862e-24 (rank : 18)
Query Neighborhood Hits	188	Target Neighborhood Hits	64	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

TBC10_MOUSE
NC score	0.447868 (rank : 65)	θ value	3.39556e-23 (rank : 19)
Query Neighborhood Hits	188	Target Neighborhood Hits	94	Shared Neighborhood Hits	25
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

UBP34_MOUSE
NC score	0.407430 (rank : 66)	θ value	0.0563607 (rank : 87)
Query Neighborhood Hits	188	Target Neighborhood Hits	189	Shared Neighborhood Hits	70
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_HUMAN
NC score	0.407332 (rank : 67)	θ value	0.0736092 (rank : 92)
Query Neighborhood Hits	188	Target Neighborhood Hits	210	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP5_HUMAN
NC score	0.406351 (rank : 68)	θ value	0.000461057 (rank : 71)
Query Neighborhood Hits	188	Target Neighborhood Hits	109	Shared Neighborhood Hits	74
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP13_HUMAN
NC score	0.404638 (rank : 69)	θ value	0.00665767 (rank : 77)
Query Neighborhood Hits	188	Target Neighborhood Hits	99	Shared Neighborhood Hits	73
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP5_MOUSE
NC score	0.400935 (rank : 70)	θ value	0.00175202 (rank : 72)
Query Neighborhood Hits	188	Target Neighborhood Hits	106	Shared Neighborhood Hits	74
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

USP9X_HUMAN
NC score	0.398476 (rank : 71)	θ value	0.0193708 (rank : 79)
Query Neighborhood Hits	188	Target Neighborhood Hits	161	Shared Neighborhood Hits	76
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
NC score	0.397872 (rank : 72)	θ value	0.0193708 (rank : 80)
Query Neighborhood Hits	188	Target Neighborhood Hits	171	Shared Neighborhood Hits	78
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9Y_HUMAN
NC score	0.394639 (rank : 73)	θ value	0.0252991 (rank : 82)
Query Neighborhood Hits	188	Target Neighborhood Hits	109	Shared Neighborhood Hits	75
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

TBCD8_MOUSE
NC score	0.379906 (rank : 74)	θ value	1.86753e-13 (rank : 37)
Query Neighborhood Hits	188	Target Neighborhood Hits	64	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z1A9	Gene names	Tbc1d8, Hblp1, Vrp
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (BUB2-like protein 1).

TBC12_HUMAN
NC score	0.375284 (rank : 75)	θ value	2.98157e-11 (rank : 47)
Query Neighborhood Hits	188	Target Neighborhood Hits	80	Shared Neighborhood Hits	20
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

UBP26_MOUSE
NC score	0.374880 (rank : 76)	θ value	0.0563607 (rank : 86)
Query Neighborhood Hits	188	Target Neighborhood Hits	107	Shared Neighborhood Hits	71
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

TBCD8_HUMAN
NC score	0.374621 (rank : 77)	θ value	7.09661e-13 (rank : 41)
Query Neighborhood Hits	188	Target Neighborhood Hits	65	Shared Neighborhood Hits	19
SwissProt Accessions	O95759, Q9UQ32	Gene names	TBC1D8, VRP
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (AD 3).

TBC14_HUMAN
NC score	0.369346 (rank : 78)	θ value	1.58096e-12 (rank : 43)
Query Neighborhood Hits	188	Target Neighborhood Hits	124	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

TBC14_MOUSE
NC score	0.366495 (rank : 79)	θ value	1.58096e-12 (rank : 44)
Query Neighborhood Hits	188	Target Neighborhood Hits	135	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CGA2, Q8CHA5	Gene names	Tbc1d14, D5Ertd110e, Kiaa1322
Domain Architecture
Description	TBC1 domain family member 14.

TBCD1_HUMAN
NC score	0.358445 (rank : 80)	θ value	1.09485e-13 (rank : 34)
Query Neighborhood Hits	188	Target Neighborhood Hits	276	Shared Neighborhood Hits	22
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

TBCD1_MOUSE
NC score	0.355338 (rank : 81)	θ value	1.86753e-13 (rank : 36)
Query Neighborhood Hits	188	Target Neighborhood Hits	241	Shared Neighborhood Hits	21
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

TBCD2_HUMAN
NC score	0.350123 (rank : 82)	θ value	4.02038e-16 (rank : 30)
Query Neighborhood Hits	188	Target Neighborhood Hits	419	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

TBCD4_MOUSE
NC score	0.347136 (rank : 83)	θ value	1.42992e-13 (rank : 35)
Query Neighborhood Hits	188	Target Neighborhood Hits	276	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD4_HUMAN
NC score	0.340098 (rank : 84)	θ value	5.43371e-13 (rank : 40)
Query Neighborhood Hits	188	Target Neighborhood Hits	357	Shared Neighborhood Hits	24
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

UBP28_HUMAN
NC score	0.299185 (rank : 85)	θ value	0.000158464 (rank : 66)
Query Neighborhood Hits	188	Target Neighborhood Hits	117	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_MOUSE
NC score	0.294484 (rank : 86)	θ value	0.00228821 (rank : 73)
Query Neighborhood Hits	188	Target Neighborhood Hits	178	Shared Neighborhood Hits	79
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

TBC16_HUMAN
NC score	0.279920 (rank : 87)	θ value	1.25267e-09 (rank : 48)
Query Neighborhood Hits	188	Target Neighborhood Hits	55	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TBP0	Gene names	TBC1D16
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 16.

UBP25_MOUSE
NC score	0.266938 (rank : 88)	θ value	0.0563607 (rank : 85)
Query Neighborhood Hits	188	Target Neighborhood Hits	116	Shared Neighborhood Hits	73
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP25_HUMAN
NC score	0.265719 (rank : 89)	θ value	0.0563607 (rank : 84)
Query Neighborhood Hits	188	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

TBC17_MOUSE
NC score	0.164648 (rank : 90)	θ value	0.0736092 (rank : 89)
Query Neighborhood Hits	188	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BYH7	Gene names	Tbc1d17
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 17.

TBC17_HUMAN
NC score	0.159318 (rank : 91)	θ value	0.163984 (rank : 94)
Query Neighborhood Hits	188	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HA65	Gene names	TBC1D17
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 17.

TBC15_MOUSE
NC score	0.153349 (rank : 92)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	188	Target Neighborhood Hits	40	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CXF4, Q3UI41	Gene names	Tbc1d15
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 15.

TBC15_HUMAN
NC score	0.150176 (rank : 93)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	188	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TC07	Gene names	TBC1D15
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 15.

GGNB1_MOUSE
NC score	0.146623 (rank : 94)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	188	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

GGNB1_HUMAN
NC score	0.106946 (rank : 95)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	188	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5YKI7, Q5YKI8	Gene names	GGNBP1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

TB22B_HUMAN
NC score	0.104201 (rank : 96)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	188	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NU19, Q5VUK9, Q7Z6P7, Q9BPV6, Q9BUT5, Q9NXB6	Gene names	TBC1D22B, C6orf197
Domain Architecture
Description	TBC1 domain family member 22B.

TB22A_MOUSE
NC score	0.097590 (rank : 97)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	188	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R5A6, Q3U268, Q3U3T0, Q8CA49	Gene names	Tbc1d22a, D15Ertd781e
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 22A.

TB22A_HUMAN
NC score	0.096361 (rank : 98)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	188	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WUA7, Q5TE47, Q6ZUH2, Q92680, Q9BVD6, Q9UGG0, Q9UGT2, Q9UGU6, Q9UH25, Q9Y4W5	Gene names	TBC1D22A, C22orf4
Domain Architecture
Description	TBC1 domain family member 22A.

BRAP_MOUSE
NC score	0.078055 (rank : 99)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	188	Target Neighborhood Hits	409	Shared Neighborhood Hits	16
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

TBC13_MOUSE
NC score	0.075255 (rank : 100)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	188	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R3D1	Gene names	Tbc1d13
Domain Architecture
Description	TBC1 domain family member 13.

TBC20_HUMAN
NC score	0.073670 (rank : 101)	θ value	0.0736092 (rank : 90)
Query Neighborhood Hits	188	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q96BZ9, Q5JWQ7, Q96NE1, Q9BYM7, Q9H140	Gene names	TBC1D20, C20orf140
Domain Architecture
Description	TBC1 domain family member 20.

TBC20_MOUSE
NC score	0.069088 (rank : 102)	θ value	0.279714 (rank : 96)
Query Neighborhood Hits	188	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D9I4, Q3TYW9, Q99LW2	Gene names	Tbc1d20
Domain Architecture
Description	TBC1 domain family member 20.

BRAP_HUMAN
NC score	0.067739 (rank : 103)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	188	Target Neighborhood Hits	560	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

TBCD5_HUMAN
NC score	0.064309 (rank : 104)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	188	Target Neighborhood Hits	70	Shared Neighborhood Hits	18
SwissProt Accessions	Q92609	Gene names	TBC1D5, KIAA0210
Domain Architecture
Description	TBC1 domain family member 5.

TBCD5_MOUSE
NC score	0.055797 (rank : 105)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	188	Target Neighborhood Hits	71	Shared Neighborhood Hits	17
SwissProt Accessions	Q80XQ2	Gene names	Tbc1d5
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 5.

HDAC6_MOUSE
NC score	0.052723 (rank : 106)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	188	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

TBCD7_MOUSE
NC score	0.052702 (rank : 107)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	188	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D0K0, Q3U0V0	Gene names	Tbc1d7
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 7.

CF064_HUMAN
NC score	0.040946 (rank : 108)	θ value	0.365318 (rank : 97)
Query Neighborhood Hits	188	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPB0, Q9H0D8	Gene names	C6orf64
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf64.

SRRM1_HUMAN
NC score	0.034359 (rank : 109)	θ value	0.47712 (rank : 101)
Query Neighborhood Hits	188	Target Neighborhood Hits	690	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
NC score	0.034332 (rank : 110)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	188	Target Neighborhood Hits	966	Shared Neighborhood Hits	48
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

NCOA6_MOUSE
NC score	0.031127 (rank : 111)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	188	Target Neighborhood Hits	1076	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

TEX15_HUMAN
NC score	0.030473 (rank : 112)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	188	Target Neighborhood Hits	174	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

ARI1B_HUMAN
NC score	0.029425 (rank : 113)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	188	Target Neighborhood Hits	567	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

PRRT1_MOUSE
NC score	0.028828 (rank : 114)	θ value	1.06291 (rank : 113)
Query Neighborhood Hits	188	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

RIN2_HUMAN
NC score	0.028751 (rank : 115)	θ value	0.0431538 (rank : 83)
Query Neighborhood Hits	188	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

ARI1A_HUMAN
NC score	0.028044 (rank : 116)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	188	Target Neighborhood Hits	787	Shared Neighborhood Hits	40
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

WASP_HUMAN
NC score	0.027287 (rank : 117)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	188	Target Neighborhood Hits	195	Shared Neighborhood Hits	19
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

SGIP1_HUMAN
NC score	0.026626 (rank : 118)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	188	Target Neighborhood Hits	198	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

NCOA6_HUMAN
NC score	0.026201 (rank : 119)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	188	Target Neighborhood Hits	1202	Shared Neighborhood Hits	56
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

WASP_MOUSE
NC score	0.025313 (rank : 120)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	188	Target Neighborhood Hits	223	Shared Neighborhood Hits	18
SwissProt Accessions	P70315	Gene names	Was, Wasp
Domain Architecture
Description	Wiskott-Aldrich syndrome protein homolog (WASp).

WASL_HUMAN
NC score	0.025273 (rank : 121)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	188	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

LCP2_HUMAN
NC score	0.025261 (rank : 122)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	188	Target Neighborhood Hits	531	Shared Neighborhood Hits	30
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

PRRT1_HUMAN
NC score	0.024945 (rank : 123)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	188	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

KCNK4_HUMAN
NC score	0.023478 (rank : 124)	θ value	0.0113563 (rank : 78)
Query Neighborhood Hits	188	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

CN032_HUMAN
NC score	0.021677 (rank : 125)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	188	Target Neighborhood Hits	267	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

NACAM_MOUSE
NC score	0.020590 (rank : 126)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	188	Target Neighborhood Hits	1866	Shared Neighborhood Hits	67
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRP1_HUMAN
NC score	0.020272 (rank : 127)	θ value	3.0926 (rank : 139)
Query Neighborhood Hits	188	Target Neighborhood Hits	385	Shared Neighborhood Hits	24
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

CN032_MOUSE
NC score	0.019934 (rank : 128)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	188	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

DBF4_HUMAN
NC score	0.019638 (rank : 129)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	188	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBU7, O75226, Q75MS6, Q75N01, Q9Y2M6	Gene names	DBF4, ASK
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (Activator of S phase Kinase).

WASL_MOUSE
NC score	0.019122 (rank : 130)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	188	Target Neighborhood Hits	339	Shared Neighborhood Hits	21
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WASIP_HUMAN
NC score	0.018658 (rank : 131)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	188	Target Neighborhood Hits	458	Shared Neighborhood Hits	23
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ICA69_MOUSE
NC score	0.018107 (rank : 132)	θ value	0.62314 (rank : 103)
Query Neighborhood Hits	188	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P97411, P97362, P97954, Q99M40, Q9R2C4	Gene names	Ica1, Icap69
Domain Architecture	No domain graphic available
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

RAI1_HUMAN
NC score	0.016770 (rank : 133)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	188	Target Neighborhood Hits	360	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RIF1_HUMAN
NC score	0.015586 (rank : 134)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	188	Target Neighborhood Hits	320	Shared Neighborhood Hits	5
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

TRIP6_HUMAN
NC score	0.015504 (rank : 135)	θ value	0.365318 (rank : 98)
Query Neighborhood Hits	188	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

TCF20_MOUSE
NC score	0.015351 (rank : 136)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	188	Target Neighborhood Hits	396	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

MEF2B_HUMAN
NC score	0.015339 (rank : 137)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	188	Target Neighborhood Hits	150	Shared Neighborhood Hits	12
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

TAF6_MOUSE
NC score	0.015078 (rank : 138)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	188	Target Neighborhood Hits	110	Shared Neighborhood Hits	9
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

MLL4_HUMAN
NC score	0.014975 (rank : 139)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	188	Target Neighborhood Hits	722	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

RD23B_HUMAN
NC score	0.014853 (rank : 140)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	188	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

PRC1_MOUSE
NC score	0.014645 (rank : 141)	θ value	0.62314 (rank : 104)
Query Neighborhood Hits	188	Target Neighborhood Hits	382	Shared Neighborhood Hits	7
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

TCF20_HUMAN
NC score	0.014629 (rank : 142)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	188	Target Neighborhood Hits	323	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

RIN3_HUMAN
NC score	0.013875 (rank : 143)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	188	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ZYX_HUMAN
NC score	0.013177 (rank : 144)	θ value	0.813845 (rank : 105)
Query Neighborhood Hits	188	Target Neighborhood Hits	387	Shared Neighborhood Hits	14
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

CRTC1_HUMAN
NC score	0.012855 (rank : 145)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	188	Target Neighborhood Hits	319	Shared Neighborhood Hits	18
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

APEH_MOUSE
NC score	0.012836 (rank : 146)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	188	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R146, Q8K029, Q8R0M9	Gene names	Apeh
Domain Architecture
Description	Acylamino-acid-releasing enzyme (EC 3.4.19.1) (AARE) (Acyl-peptide hydrolase) (APH) (Acylaminoacyl-peptidase).

NFAC4_HUMAN
NC score	0.012731 (rank : 147)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	188	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

BSN_MOUSE
NC score	0.012621 (rank : 148)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	188	Target Neighborhood Hits	2057	Shared Neighborhood Hits	66
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ATX2_MOUSE
NC score	0.012509 (rank : 149)	θ value	3.0926 (rank : 136)
Query Neighborhood Hits	188	Target Neighborhood Hits	445	Shared Neighborhood Hits	31
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

SYN1_MOUSE
NC score	0.012145 (rank : 150)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	188	Target Neighborhood Hits	363	Shared Neighborhood Hits	24
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

ZN318_MOUSE
NC score	0.011936 (rank : 151)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	188	Target Neighborhood Hits	642	Shared Neighborhood Hits	19
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

HCN4_MOUSE
NC score	0.011648 (rank : 152)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	188	Target Neighborhood Hits	284	Shared Neighborhood Hits	16
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.011283 (rank : 153)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	188	Target Neighborhood Hits	369	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

SRTD2_MOUSE
NC score	0.010895 (rank : 154)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	188	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJG5, Q8C609, Q91WL3, Q925E5	Gene names	Sertad2, Kiaa0127
Domain Architecture
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

PELP1_MOUSE
NC score	0.010793 (rank : 155)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	188	Target Neighborhood Hits	709	Shared Neighborhood Hits	32
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

CBP_MOUSE
NC score	0.010522 (rank : 156)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	188	Target Neighborhood Hits	1051	Shared Neighborhood Hits	47
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SYNJ1_HUMAN
NC score	0.010032 (rank : 157)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	188	Target Neighborhood Hits	498	Shared Neighborhood Hits	24
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

HCN2_MOUSE
NC score	0.010013 (rank : 158)	θ value	3.0926 (rank : 138)
Query Neighborhood Hits	188	Target Neighborhood Hits	278	Shared Neighborhood Hits	12
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

DC1L2_MOUSE
NC score	0.009844 (rank : 159)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	188	Target Neighborhood Hits	173	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

LPXN_HUMAN
NC score	0.009835 (rank : 160)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	188	Target Neighborhood Hits	159	Shared Neighborhood Hits	5
SwissProt Accessions	O60711	Gene names	LPXN, LDLP
Domain Architecture
Description	Leupaxin.

SAM68_MOUSE
NC score	0.009581 (rank : 161)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	188	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

YLPM1_MOUSE
NC score	0.009489 (rank : 162)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	188	Target Neighborhood Hits	505	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

LPXN_MOUSE
NC score	0.009420 (rank : 163)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	188	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

TBCEL_HUMAN
NC score	0.009359 (rank : 164)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	188	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q5QJ74	Gene names	LRRC35
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35).

PER3_HUMAN
NC score	0.009260 (rank : 165)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	188	Target Neighborhood Hits	479	Shared Neighborhood Hits	34
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

SF01_HUMAN
NC score	0.009226 (rank : 166)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	188	Target Neighborhood Hits	287	Shared Neighborhood Hits	18
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

PLS1_HUMAN
NC score	0.008774 (rank : 167)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	188	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	O15162	Gene names	PLSCR1
Domain Architecture
Description	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b).

WDR33_HUMAN
NC score	0.008746 (rank : 168)	θ value	0.125558 (rank : 93)
Query Neighborhood Hits	188	Target Neighborhood Hits	638	Shared Neighborhood Hits	17
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

TBCEL_MOUSE
NC score	0.008611 (rank : 169)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	188	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C5W3, Q8C7A5	Gene names	Lrrc35
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35).

COIA1_HUMAN
NC score	0.008295 (rank : 170)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	188	Target Neighborhood Hits	447	Shared Neighborhood Hits	19
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CECR6_MOUSE
NC score	0.008144 (rank : 171)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	188	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MX7	Gene names	Cecr6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6 homolog.

FANCJ_MOUSE
NC score	0.007933 (rank : 172)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	188	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SXJ3, Q8BJQ8, Q8BKI6	Gene names	Brip1, Bach1, Fancj
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

PLS1_MOUSE
NC score	0.007659 (rank : 173)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	188	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JJ00, O54730, O54731, Q9D1F8	Gene names	Plscr1, Tra1b, Tras1
Domain Architecture
Description	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Transplantability-associated protein 1) (TRA1) (NOR1).

TS101_HUMAN
NC score	0.007269 (rank : 174)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	188	Target Neighborhood Hits	359	Shared Neighborhood Hits	6
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

SNX18_HUMAN
NC score	0.006948 (rank : 175)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	188	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q96RF0	Gene names	SNAG1, SNX18
Domain Architecture
Description	Sorting nexin-18 (Sorting nexin-associated Golgi protein 1).

CO3A1_HUMAN
NC score	0.006559 (rank : 176)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	188	Target Neighborhood Hits	452	Shared Neighborhood Hits	19
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

PDC6I_MOUSE
NC score	0.006358 (rank : 177)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	188	Target Neighborhood Hits	275	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

TISD_HUMAN
NC score	0.006324 (rank : 178)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	188	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P47974, Q9BSJ3	Gene names	ZFP36L2, BRF2, ERF2, TIS11D
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein) (EGF-response factor 2) (ERF-2).

ASPP1_HUMAN
NC score	0.006297 (rank : 179)	θ value	4.03905 (rank : 145)
Query Neighborhood Hits	188	Target Neighborhood Hits	956	Shared Neighborhood Hits	24
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

IRX2_HUMAN
NC score	0.006226 (rank : 180)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	188	Target Neighborhood Hits	358	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

SETBP_MOUSE
NC score	0.006183 (rank : 181)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	188	Target Neighborhood Hits	352	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

NMDE4_MOUSE
NC score	0.005878 (rank : 182)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	188	Target Neighborhood Hits	158	Shared Neighborhood Hits	8
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

ADA19_HUMAN
NC score	0.005850 (rank : 183)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	188	Target Neighborhood Hits	381	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

SFPQ_HUMAN
NC score	0.005647 (rank : 184)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	188	Target Neighborhood Hits	986	Shared Neighborhood Hits	22
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SEM6C_MOUSE
NC score	0.005343 (rank : 185)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	188	Target Neighborhood Hits	352	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

HXC10_HUMAN
NC score	0.004091 (rank : 186)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	188	Target Neighborhood Hits	417	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYD6, O15219, O15220, Q9BVD5	Gene names	HOXC10
Domain Architecture
Description	Homeobox protein Hox-C10.

CATW_HUMAN
NC score	0.003670 (rank : 187)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	188	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P56202, Q86VT4	Gene names	CTSW
Domain Architecture
Description	Cathepsin W precursor (EC 3.4.22.-) (Lymphopain).

DAAM1_MOUSE
NC score	0.002710 (rank : 188)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	188	Target Neighborhood Hits	443	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

CSKI2_HUMAN
NC score	0.002509 (rank : 189)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	188	Target Neighborhood Hits	747	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CAC1E_HUMAN
NC score	0.001510 (rank : 190)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	188	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

ITSN1_HUMAN
NC score	0.000873 (rank : 191)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	188	Target Neighborhood Hits	1757	Shared Neighborhood Hits	36
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

GP133_HUMAN
NC score	0.000575 (rank : 192)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	188	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

WNK2_HUMAN
NC score	0.000407 (rank : 193)	θ value	0.47712 (rank : 102)
Query Neighborhood Hits	188	Target Neighborhood Hits	1407	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

NKX61_HUMAN
NC score	-0.000241 (rank : 194)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	188	Target Neighborhood Hits	431	Shared Neighborhood Hits	10
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

STF1_MOUSE
NC score	-0.000246 (rank : 195)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	188	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

PROP1_HUMAN
NC score	-0.000604 (rank : 196)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	188	Target Neighborhood Hits	354	Shared Neighborhood Hits	5
SwissProt Accessions	O75360	Gene names	PROP1
Domain Architecture
Description	Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor).

SPEG_HUMAN
NC score	-0.003307 (rank : 197)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	188	Target Neighborhood Hits	1762	Shared Neighborhood Hits	33
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

STK10_HUMAN
NC score	-0.003881 (rank : 198)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	188	Target Neighborhood Hits	1921	Shared Neighborhood Hits	30
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ZN648_HUMAN
NC score	-0.004806 (rank : 199)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	188	Target Neighborhood Hits	751	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T619	Gene names	ZNF648
Domain Architecture	No domain graphic available
Description	Zinc finger protein 648.

TNK1_HUMAN
NC score	-0.005402 (rank : 200)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	188	Target Neighborhood Hits	815	Shared Neighborhood Hits	9
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

ULK1_HUMAN
NC score	-0.006019 (rank : 201)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	188	Target Neighborhood Hits	1121	Shared Neighborhood Hits	25
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

EVI1_MOUSE
NC score	-0.006658 (rank : 202)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	188	Target Neighborhood Hits	826	Shared Neighborhood Hits	5
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.