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Network neighborhood for query Sequence : USP9X_MOUSE

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USP9X_MOUSE
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

USP9X_HUMAN
θ value	0 (rank : 1)	NC score	0.998198 (rank : 2)
Query Neighborhood Hits	171	Target Neighborhood Hits	161	Shared Neighborhood Hits	148
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	171	Target Neighborhood Hits	171	Shared Neighborhood Hits	171
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9Y_HUMAN
θ value	0 (rank : 3)	NC score	0.994715 (rank : 3)
Query Neighborhood Hits	171	Target Neighborhood Hits	109	Shared Neighborhood Hits	89
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP24_HUMAN
θ value	4.52334e-185 (rank : 4)	NC score	0.932613 (rank : 4)
Query Neighborhood Hits	171	Target Neighborhood Hits	96	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP34_HUMAN
θ value	1.90147e-66 (rank : 5)	NC score	0.806638 (rank : 6)
Query Neighborhood Hits	171	Target Neighborhood Hits	210	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
θ value	1.2325e-65 (rank : 6)	NC score	0.806973 (rank : 5)
Query Neighborhood Hits	171	Target Neighborhood Hits	189	Shared Neighborhood Hits	71
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP48_HUMAN
θ value	3.3877e-31 (rank : 7)	NC score	0.776188 (rank : 8)
Query Neighborhood Hits	171	Target Neighborhood Hits	101	Shared Neighborhood Hits	74
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP47_MOUSE
θ value	3.74554e-30 (rank : 8)	NC score	0.756514 (rank : 11)
Query Neighborhood Hits	171	Target Neighborhood Hits	135	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP48_MOUSE
θ value	3.74554e-30 (rank : 9)	NC score	0.772566 (rank : 10)
Query Neighborhood Hits	171	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP47_HUMAN
θ value	4.89182e-30 (rank : 10)	NC score	0.753572 (rank : 12)
Query Neighborhood Hits	171	Target Neighborhood Hits	149	Shared Neighborhood Hits	72
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP7_HUMAN
θ value	3.87602e-27 (rank : 11)	NC score	0.782991 (rank : 7)
Query Neighborhood Hits	171	Target Neighborhood Hits	93	Shared Neighborhood Hits	71
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP40_HUMAN
θ value	4.43474e-23 (rank : 12)	NC score	0.772734 (rank : 9)
Query Neighborhood Hits	171	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP8_HUMAN
θ value	7.32683e-18 (rank : 13)	NC score	0.616122 (rank : 37)
Query Neighborhood Hits	171	Target Neighborhood Hits	751	Shared Neighborhood Hits	82
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP8_MOUSE
θ value	2.7842e-17 (rank : 14)	NC score	0.648673 (rank : 28)
Query Neighborhood Hits	171	Target Neighborhood Hits	362	Shared Neighborhood Hits	76
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP36_HUMAN
θ value	4.74913e-17 (rank : 15)	NC score	0.693640 (rank : 19)
Query Neighborhood Hits	171	Target Neighborhood Hits	232	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP12_HUMAN
θ value	1.058e-16 (rank : 16)	NC score	0.715011 (rank : 15)
Query Neighborhood Hits	171	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UB17L_HUMAN
θ value	3.07829e-16 (rank : 17)	NC score	0.698266 (rank : 17)
Query Neighborhood Hits	171	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP46_HUMAN
θ value	3.07829e-16 (rank : 18)	NC score	0.716360 (rank : 13)
Query Neighborhood Hits	171	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	3.07829e-16 (rank : 19)	NC score	0.716360 (rank : 14)
Query Neighborhood Hits	171	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP3_HUMAN
θ value	1.99529e-15 (rank : 20)	NC score	0.657958 (rank : 26)
Query Neighborhood Hits	171	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP22_HUMAN
θ value	4.44505e-15 (rank : 21)	NC score	0.671946 (rank : 20)
Query Neighborhood Hits	171	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
θ value	7.58209e-15 (rank : 22)	NC score	0.670359 (rank : 22)
Query Neighborhood Hits	171	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP42_HUMAN
θ value	7.58209e-15 (rank : 23)	NC score	0.659759 (rank : 24)
Query Neighborhood Hits	171	Target Neighborhood Hits	445	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP3_MOUSE
θ value	9.90251e-15 (rank : 24)	NC score	0.659473 (rank : 25)
Query Neighborhood Hits	171	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP51_HUMAN
θ value	1.86753e-13 (rank : 25)	NC score	0.663577 (rank : 23)
Query Neighborhood Hits	171	Target Neighborhood Hits	162	Shared Neighborhood Hits	73
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP33_HUMAN
θ value	2.43908e-13 (rank : 26)	NC score	0.646166 (rank : 29)
Query Neighborhood Hits	171	Target Neighborhood Hits	157	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP49_HUMAN
θ value	2.43908e-13 (rank : 27)	NC score	0.631254 (rank : 31)
Query Neighborhood Hits	171	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBPW_MOUSE
θ value	5.43371e-13 (rank : 28)	NC score	0.693882 (rank : 18)
Query Neighborhood Hits	171	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP20_HUMAN
θ value	7.09661e-13 (rank : 29)	NC score	0.652802 (rank : 27)
Query Neighborhood Hits	171	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP49_MOUSE
θ value	1.2105e-12 (rank : 30)	NC score	0.628022 (rank : 34)
Query Neighborhood Hits	171	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP15_HUMAN
θ value	1.33837e-11 (rank : 31)	NC score	0.558561 (rank : 44)
Query Neighborhood Hits	171	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP44_HUMAN
θ value	1.33837e-11 (rank : 32)	NC score	0.629282 (rank : 33)
Query Neighborhood Hits	171	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP15_MOUSE
θ value	1.74796e-11 (rank : 33)	NC score	0.558442 (rank : 45)
Query Neighborhood Hits	171	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP18_HUMAN
θ value	3.89403e-11 (rank : 34)	NC score	0.707125 (rank : 16)
Query Neighborhood Hits	171	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP2_HUMAN
θ value	3.29651e-10 (rank : 35)	NC score	0.631089 (rank : 32)
Query Neighborhood Hits	171	Target Neighborhood Hits	84	Shared Neighborhood Hits	73
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP38_HUMAN
θ value	3.29651e-10 (rank : 36)	NC score	0.572375 (rank : 41)
Query Neighborhood Hits	171	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP38_MOUSE
θ value	1.63604e-09 (rank : 37)	NC score	0.558716 (rank : 43)
Query Neighborhood Hits	171	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP2_MOUSE
θ value	2.79066e-09 (rank : 38)	NC score	0.627814 (rank : 35)
Query Neighborhood Hits	171	Target Neighborhood Hits	86	Shared Neighborhood Hits	74
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP10_HUMAN
θ value	4.76016e-09 (rank : 39)	NC score	0.541484 (rank : 50)
Query Neighborhood Hits	171	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP18_MOUSE
θ value	8.11959e-09 (rank : 40)	NC score	0.670948 (rank : 21)
Query Neighborhood Hits	171	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP50_MOUSE
θ value	8.11959e-09 (rank : 41)	NC score	0.645946 (rank : 30)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP11_HUMAN
θ value	1.06045e-08 (rank : 42)	NC score	0.555236 (rank : 46)
Query Neighborhood Hits	171	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP28_MOUSE
θ value	1.06045e-08 (rank : 43)	NC score	0.472004 (rank : 58)
Query Neighborhood Hits	171	Target Neighborhood Hits	178	Shared Neighborhood Hits	73
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_HUMAN
θ value	1.38499e-08 (rank : 44)	NC score	0.471263 (rank : 59)
Query Neighborhood Hits	171	Target Neighborhood Hits	117	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP10_MOUSE
θ value	1.80886e-08 (rank : 45)	NC score	0.538301 (rank : 52)
Query Neighborhood Hits	171	Target Neighborhood Hits	150	Shared Neighborhood Hits	70
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP31_HUMAN
θ value	1.80886e-08 (rank : 46)	NC score	0.549709 (rank : 48)
Query Neighborhood Hits	171	Target Neighborhood Hits	293	Shared Neighborhood Hits	75
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP21_MOUSE
θ value	5.26297e-08 (rank : 47)	NC score	0.610652 (rank : 38)
Query Neighborhood Hits	171	Target Neighborhood Hits	101	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP16_HUMAN
θ value	1.53129e-07 (rank : 48)	NC score	0.594202 (rank : 40)
Query Neighborhood Hits	171	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP21_HUMAN
θ value	1.53129e-07 (rank : 49)	NC score	0.608805 (rank : 39)
Query Neighborhood Hits	171	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP50_HUMAN
θ value	1.53129e-07 (rank : 50)	NC score	0.621819 (rank : 36)
Query Neighborhood Hits	171	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP43_HUMAN
θ value	4.45536e-07 (rank : 51)	NC score	0.537326 (rank : 53)
Query Neighborhood Hits	171	Target Neighborhood Hits	144	Shared Neighborhood Hits	76
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP14_HUMAN
θ value	5.81887e-07 (rank : 52)	NC score	0.552981 (rank : 47)
Query Neighborhood Hits	171	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP14_MOUSE
θ value	9.92553e-07 (rank : 53)	NC score	0.517489 (rank : 56)
Query Neighborhood Hits	171	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP25_HUMAN
θ value	9.92553e-07 (rank : 54)	NC score	0.449796 (rank : 64)
Query Neighborhood Hits	171	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP25_MOUSE
θ value	1.29631e-06 (rank : 55)	NC score	0.450933 (rank : 63)
Query Neighborhood Hits	171	Target Neighborhood Hits	116	Shared Neighborhood Hits	72
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP43_MOUSE
θ value	1.69304e-06 (rank : 56)	NC score	0.541326 (rank : 51)
Query Neighborhood Hits	171	Target Neighborhood Hits	130	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP4_HUMAN
θ value	1.69304e-06 (rank : 57)	NC score	0.534718 (rank : 54)
Query Neighborhood Hits	171	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP4_MOUSE
θ value	1.69304e-06 (rank : 58)	NC score	0.533549 (rank : 55)
Query Neighborhood Hits	171	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

SNUT2_MOUSE
θ value	1.43324e-05 (rank : 59)	NC score	0.463275 (rank : 60)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

SNUT2_HUMAN
θ value	2.44474e-05 (rank : 60)	NC score	0.453644 (rank : 62)
Query Neighborhood Hits	171	Target Neighborhood Hits	79	Shared Neighborhood Hits	59
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP1_HUMAN
θ value	0.00035302 (rank : 61)	NC score	0.547390 (rank : 49)
Query Neighborhood Hits	171	Target Neighborhood Hits	259	Shared Neighborhood Hits	75
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP37_HUMAN
θ value	0.00035302 (rank : 62)	NC score	0.485707 (rank : 57)
Query Neighborhood Hits	171	Target Neighborhood Hits	208	Shared Neighborhood Hits	77
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP35_HUMAN
θ value	0.000602161 (rank : 63)	NC score	0.559494 (rank : 42)
Query Neighborhood Hits	171	Target Neighborhood Hits	223	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP32_HUMAN
θ value	0.00175202 (rank : 64)	NC score	0.427352 (rank : 65)
Query Neighborhood Hits	171	Target Neighborhood Hits	170	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP5_HUMAN
θ value	0.00228821 (rank : 65)	NC score	0.396172 (rank : 69)
Query Neighborhood Hits	171	Target Neighborhood Hits	109	Shared Neighborhood Hits	73
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
θ value	0.00228821 (rank : 66)	NC score	0.398272 (rank : 67)
Query Neighborhood Hits	171	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP13_HUMAN
θ value	0.00509761 (rank : 67)	NC score	0.377098 (rank : 71)
Query Neighborhood Hits	171	Target Neighborhood Hits	99	Shared Neighborhood Hits	72
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP26_HUMAN
θ value	0.00665767 (rank : 68)	NC score	0.381735 (rank : 70)
Query Neighborhood Hits	171	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

PRP1_HUMAN
θ value	0.0113563 (rank : 69)	NC score	0.062289 (rank : 78)
Query Neighborhood Hits	171	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

UBP26_MOUSE
θ value	0.0193708 (rank : 70)	NC score	0.332182 (rank : 73)
Query Neighborhood Hits	171	Target Neighborhood Hits	107	Shared Neighborhood Hits	72
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP6_HUMAN
θ value	0.0193708 (rank : 71)	NC score	0.397872 (rank : 68)
Query Neighborhood Hits	171	Target Neighborhood Hits	188	Shared Neighborhood Hits	78
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

DMD_MOUSE
θ value	0.0252991 (rank : 72)	NC score	0.022772 (rank : 99)
Query Neighborhood Hits	171	Target Neighborhood Hits	1111	Shared Neighborhood Hits	23
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

UBP29_HUMAN
θ value	0.0563607 (rank : 73)	NC score	0.408163 (rank : 66)
Query Neighborhood Hits	171	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

PRB3_HUMAN
θ value	0.0736092 (rank : 74)	NC score	0.048162 (rank : 81)
Query Neighborhood Hits	171	Target Neighborhood Hits	318	Shared Neighborhood Hits	18
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

CCDC9_HUMAN
θ value	0.0961366 (rank : 75)	NC score	0.055527 (rank : 80)
Query Neighborhood Hits	171	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

IMMT_HUMAN
θ value	0.0961366 (rank : 76)	NC score	0.021925 (rank : 100)
Query Neighborhood Hits	171	Target Neighborhood Hits	494	Shared Neighborhood Hits	10
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

PRB4S_HUMAN
θ value	0.163984 (rank : 77)	NC score	0.047752 (rank : 82)
Query Neighborhood Hits	171	Target Neighborhood Hits	330	Shared Neighborhood Hits	17
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

UBP29_MOUSE
θ value	0.163984 (rank : 78)	NC score	0.376220 (rank : 72)
Query Neighborhood Hits	171	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

PRPC_HUMAN
θ value	0.279714 (rank : 79)	NC score	0.092917 (rank : 75)
Query Neighborhood Hits	171	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

CHRC1_HUMAN
θ value	0.365318 (rank : 80)	NC score	0.069656 (rank : 77)
Query Neighborhood Hits	171	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRG0	Gene names	CHRAC1, CHRAC15
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15).

NEIL3_HUMAN
θ value	0.365318 (rank : 81)	NC score	0.041046 (rank : 84)
Query Neighborhood Hits	171	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

OGFR_MOUSE
θ value	0.365318 (rank : 82)	NC score	0.029172 (rank : 92)
Query Neighborhood Hits	171	Target Neighborhood Hits	584	Shared Neighborhood Hits	25
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

SYNE1_HUMAN
θ value	0.365318 (rank : 83)	NC score	0.016247 (rank : 107)
Query Neighborhood Hits	171	Target Neighborhood Hits	1484	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

MADCA_HUMAN
θ value	0.47712 (rank : 84)	NC score	0.046042 (rank : 83)
Query Neighborhood Hits	171	Target Neighborhood Hits	221	Shared Neighborhood Hits	9
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

PRP5_HUMAN
θ value	0.47712 (rank : 85)	NC score	0.097307 (rank : 74)
Query Neighborhood Hits	171	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

SMC2_MOUSE
θ value	0.47712 (rank : 86)	NC score	0.014057 (rank : 111)
Query Neighborhood Hits	171	Target Neighborhood Hits	1131	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SYN3_HUMAN
θ value	0.813845 (rank : 87)	NC score	0.027818 (rank : 93)
Query Neighborhood Hits	171	Target Neighborhood Hits	203	Shared Neighborhood Hits	6
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

CS007_HUMAN
θ value	1.06291 (rank : 88)	NC score	0.023385 (rank : 98)
Query Neighborhood Hits	171	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

SYN1_MOUSE
θ value	1.06291 (rank : 89)	NC score	0.016645 (rank : 104)
Query Neighborhood Hits	171	Target Neighborhood Hits	363	Shared Neighborhood Hits	11
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

ACK1_HUMAN
θ value	1.38821 (rank : 90)	NC score	-0.001165 (rank : 169)
Query Neighborhood Hits	171	Target Neighborhood Hits	1140	Shared Neighborhood Hits	22
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

CAC1B_HUMAN
θ value	1.38821 (rank : 91)	NC score	0.010386 (rank : 127)
Query Neighborhood Hits	171	Target Neighborhood Hits	257	Shared Neighborhood Hits	10
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAF1B_MOUSE
θ value	1.38821 (rank : 92)	NC score	0.010740 (rank : 125)
Query Neighborhood Hits	171	Target Neighborhood Hits	385	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

LIX1_MOUSE
θ value	1.38821 (rank : 93)	NC score	0.031058 (rank : 91)
Query Neighborhood Hits	171	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P566, Q8VHY1, Q9CYH4	Gene names	Lix1
Domain Architecture	No domain graphic available
Description	Protein limb expression 1 homolog.

BRD4_HUMAN
θ value	1.81305 (rank : 94)	NC score	0.008485 (rank : 137)
Query Neighborhood Hits	171	Target Neighborhood Hits	851	Shared Neighborhood Hits	25
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CREB5_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.026233 (rank : 94)
Query Neighborhood Hits	171	Target Neighborhood Hits	222	Shared Neighborhood Hits	11
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

MAGI2_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.013020 (rank : 118)
Query Neighborhood Hits	171	Target Neighborhood Hits	373	Shared Neighborhood Hits	11
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

SALL2_MOUSE
θ value	1.81305 (rank : 97)	NC score	0.002763 (rank : 158)
Query Neighborhood Hits	171	Target Neighborhood Hits	836	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

BCL7C_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.031266 (rank : 89)
Query Neighborhood Hits	171	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

BIRC6_HUMAN
θ value	2.36792 (rank : 99)	NC score	0.031155 (rank : 90)
Query Neighborhood Hits	171	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

SFPQ_MOUSE
θ value	2.36792 (rank : 100)	NC score	0.009129 (rank : 134)
Query Neighborhood Hits	171	Target Neighborhood Hits	958	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SGOL1_MOUSE
θ value	2.36792 (rank : 101)	NC score	0.025687 (rank : 95)
Query Neighborhood Hits	171	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CXH7, Q3U4K4, Q588H1, Q8BKW2	Gene names	Sgol1, Sgo1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1.

CU013_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.020165 (rank : 102)
Query Neighborhood Hits	171	Target Neighborhood Hits	405	Shared Neighborhood Hits	9
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

H6ST3_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.019432 (rank : 103)
Query Neighborhood Hits	171	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZP7, Q5W0L0, Q68CW6	Gene names	HS6ST3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3).

AN13B_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.007916 (rank : 142)
Query Neighborhood Hits	171	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

BPTF_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.009395 (rank : 133)
Query Neighborhood Hits	171	Target Neighborhood Hits	786	Shared Neighborhood Hits	12
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CI126_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.034595 (rank : 85)
Query Neighborhood Hits	171	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N9R8, Q5T163, Q8N1I4	Gene names	C9orf126
Domain Architecture	No domain graphic available
Description	Protein C9orf126.

CI126_MOUSE
θ value	4.03905 (rank : 107)	NC score	0.034579 (rank : 86)
Query Neighborhood Hits	171	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C8N2, Q8C409, Q8C8K2	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf126 homolog.

FGD6_MOUSE
θ value	4.03905 (rank : 108)	NC score	0.008126 (rank : 141)
Query Neighborhood Hits	171	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

GON4L_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.015790 (rank : 108)
Query Neighborhood Hits	171	Target Neighborhood Hits	455	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

KIFC2_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.007133 (rank : 146)
Query Neighborhood Hits	171	Target Neighborhood Hits	237	Shared Neighborhood Hits	8
SwissProt Accessions	Q96AC6	Gene names	KIFC2
Domain Architecture
Description	Kinesin-like protein KIFC2.

MLL2_HUMAN
θ value	4.03905 (rank : 111)	NC score	0.008865 (rank : 135)
Query Neighborhood Hits	171	Target Neighborhood Hits	1788	Shared Neighborhood Hits	43
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PHF10_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.008403 (rank : 139)
Query Neighborhood Hits	171	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

SP6_MOUSE
θ value	4.03905 (rank : 113)	NC score	0.000021 (rank : 167)
Query Neighborhood Hits	171	Target Neighborhood Hits	704	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ESX2, Q6VM22	Gene names	Sp6, Epfn, Klf14
Domain Architecture	No domain graphic available
Description	Transcription factor Sp6 (Krueppel-like factor 14) (Epiprofin).

WDR33_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.004055 (rank : 152)
Query Neighborhood Hits	171	Target Neighborhood Hits	638	Shared Neighborhood Hits	17
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

ARY1_MOUSE
θ value	5.27518 (rank : 115)	NC score	0.013488 (rank : 113)
Query Neighborhood Hits	171	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P50294	Gene names	Nat1, Aac1
Domain Architecture
Description	Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (N-acetyltransferase type 1) (NAT-1).

ATBF1_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.001278 (rank : 163)
Query Neighborhood Hits	171	Target Neighborhood Hits	1547	Shared Neighborhood Hits	14
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BLNK_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.010925 (rank : 124)
Query Neighborhood Hits	171	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

CALX_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.021680 (rank : 101)
Query Neighborhood Hits	171	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

COBA1_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.007238 (rank : 145)
Query Neighborhood Hits	171	Target Neighborhood Hits	487	Shared Neighborhood Hits	22
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

DMD_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.009889 (rank : 128)
Query Neighborhood Hits	171	Target Neighborhood Hits	1135	Shared Neighborhood Hits	18
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

EMIL2_MOUSE
θ value	5.27518 (rank : 121)	NC score	0.012930 (rank : 119)
Query Neighborhood Hits	171	Target Neighborhood Hits	485	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

FGD6_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.007376 (rank : 144)
Query Neighborhood Hits	171	Target Neighborhood Hits	237	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FRAP_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.013216 (rank : 115)
Query Neighborhood Hits	171	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.013217 (rank : 114)
Query Neighborhood Hits	171	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

IPP1_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.024349 (rank : 97)
Query Neighborhood Hits	171	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERT9	Gene names	Ppp1r1a
Domain Architecture
Description	Protein phosphatase inhibitor 1 (IPP-1) (I-1).

KS6C1_MOUSE
θ value	5.27518 (rank : 126)	NC score	-0.001659 (rank : 172)
Query Neighborhood Hits	171	Target Neighborhood Hits	700	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

MAGI2_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.009477 (rank : 132)
Query Neighborhood Hits	171	Target Neighborhood Hits	370	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MIB2_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.003669 (rank : 153)
Query Neighborhood Hits	171	Target Neighborhood Hits	438	Shared Neighborhood Hits	8
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

NIN_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.002376 (rank : 159)
Query Neighborhood Hits	171	Target Neighborhood Hits	1376	Shared Neighborhood Hits	21
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

PRR6_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.025399 (rank : 96)
Query Neighborhood Hits	171	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z7K6, Q3L8N5, Q8NFH6	Gene names	PRR6
Domain Architecture	No domain graphic available
Description	Proline-rich protein 6 (Nuclear protein p30).

SALL2_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.000707 (rank : 164)
Query Neighborhood Hits	171	Target Neighborhood Hits	835	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

TR13C_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.031750 (rank : 88)
Query Neighborhood Hits	171	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RJ3	Gene names	TNFRSF13C, BAFFR, BR3
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13C (B cell- activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (CD268 antigen).

AFF2_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.008298 (rank : 140)
Query Neighborhood Hits	171	Target Neighborhood Hits	225	Shared Neighborhood Hits	6
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

AMBN_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.011072 (rank : 123)
Query Neighborhood Hits	171	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP70, Q9H2X1, Q9H4L1	Gene names	AMBN
Domain Architecture
Description	Ameloblastin precursor.

CF211_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.031916 (rank : 87)
Query Neighborhood Hits	171	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H993, Q96FC6, Q9UFY5	Gene names	C6orf211
Domain Architecture	No domain graphic available
Description	UPF0364 protein C6orf211.

DONS_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.009681 (rank : 129)
Query Neighborhood Hits	171	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYP3, Q9NSR9, Q9NVZ5, Q9NYP1, Q9NYP2	Gene names	DONSON, C21orf60
Domain Architecture	No domain graphic available
Description	Protein downstream neighbor of Son (B17).

EMID1_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.007583 (rank : 143)
Query Neighborhood Hits	171	Target Neighborhood Hits	230	Shared Neighborhood Hits	9
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

GCM1_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.013184 (rank : 117)
Query Neighborhood Hits	171	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NP62, Q5T0X0, Q99468, Q9P1X3	Gene names	GCM1, GCMA
Domain Architecture
Description	Chorion-specific transcription factor GCMa (Glial cells missing homolog 1) (GCM motif protein 1) (hGCMa).

JADE3_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.006554 (rank : 147)
Query Neighborhood Hits	171	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

MINT_HUMAN
θ value	6.88961 (rank : 140)	NC score	0.009602 (rank : 130)
Query Neighborhood Hits	171	Target Neighborhood Hits	1291	Shared Neighborhood Hits	22
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MINT_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.011259 (rank : 121)
Query Neighborhood Hits	171	Target Neighborhood Hits	1514	Shared Neighborhood Hits	34
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NUFP2_MOUSE
θ value	6.88961 (rank : 142)	NC score	0.016256 (rank : 106)
Query Neighborhood Hits	171	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q5F2E7, Q3TCE2, Q3V195, Q80TF1	Gene names	Nufip2, Kiaa1321
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 2 (FMRP- interacting protein 2) (82 kDa FMRP-interacting protein) (82-FIP).

PAIP1_HUMAN
θ value	6.88961 (rank : 143)	NC score	0.013214 (rank : 116)
Query Neighborhood Hits	171	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

PDZD8_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.014037 (rank : 112)
Query Neighborhood Hits	171	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

RTN4R_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.001357 (rank : 161)
Query Neighborhood Hits	171	Target Neighborhood Hits	271	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZR6	Gene names	RTN4R, NOGOR
Domain Architecture
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

RYK_HUMAN
θ value	6.88961 (rank : 146)	NC score	-0.001206 (rank : 170)
Query Neighborhood Hits	171	Target Neighborhood Hits	701	Shared Neighborhood Hits	5
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	6.88961 (rank : 147)	NC score	-0.001368 (rank : 171)
Query Neighborhood Hits	171	Target Neighborhood Hits	715	Shared Neighborhood Hits	5
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

UBP30_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.455541 (rank : 61)
Query Neighborhood Hits	171	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

ZN409_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.008552 (rank : 136)
Query Neighborhood Hits	171	Target Neighborhood Hits	842	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

ADA29_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.000053 (rank : 166)
Query Neighborhood Hits	171	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

CAC1C_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.003632 (rank : 154)
Query Neighborhood Hits	171	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAH9_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.004540 (rank : 151)
Query Neighborhood Hits	171	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q16790	Gene names	CA9, G250, MN
Domain Architecture
Description	Carbonic anhydrase 9 precursor (EC 4.2.1.1) (Carbonic anhydrase IX) (Carbonate dehydratase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC- associated antigen G250) (pMW1).

CENG1_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.001641 (rank : 160)
Query Neighborhood Hits	171	Target Neighborhood Hits	531	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

EHD4_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.005236 (rank : 149)
Query Neighborhood Hits	171	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H223, Q9HAR1, Q9NZN2	Gene names	EHD4, HCA10, HCA11
Domain Architecture
Description	EH-domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11).

ENAM_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.011162 (rank : 122)
Query Neighborhood Hits	171	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

FA47A_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.014548 (rank : 110)
Query Neighborhood Hits	171	Target Neighborhood Hits	451	Shared Neighborhood Hits	19
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

H6ST3_MOUSE
θ value	8.99809 (rank : 157)	NC score	0.009572 (rank : 131)
Query Neighborhood Hits	171	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QYK4	Gene names	Hs6st3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3) (mHS6ST- 3).

HCN2_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.003221 (rank : 156)
Query Neighborhood Hits	171	Target Neighborhood Hits	369	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HRG_HUMAN
θ value	8.99809 (rank : 159)	NC score	0.015325 (rank : 109)
Query Neighborhood Hits	171	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	P04196	Gene names	HRG
Domain Architecture
Description	Histidine-rich glycoprotein precursor (Histidine-proline-rich glycoprotein) (HPRG).

LRC40_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.000667 (rank : 165)
Query Neighborhood Hits	171	Target Neighborhood Hits	311	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CRC8, Q78WQ9, Q8BS83	Gene names	Lrrc40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

LRC8D_MOUSE
θ value	8.99809 (rank : 161)	NC score	-0.000277 (rank : 168)
Query Neighborhood Hits	171	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGR2, Q3UVA9, Q8CI13	Gene names	Lrrc8d, Lrrc5
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8D.

MYH13_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.001282 (rank : 162)
Query Neighborhood Hits	171	Target Neighborhood Hits	1504	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

NCOA4_HUMAN
θ value	8.99809 (rank : 163)	NC score	0.016590 (rank : 105)
Query Neighborhood Hits	171	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q13772, Q14239	Gene names	NCOA4, ARA70, ELE1, RFG
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 4 (NCoA-4) (70 kDa androgen receptor coactivator) (70 kDa AR-activator) (Ret-activating protein ELE1).

PPRB_MOUSE
θ value	8.99809 (rank : 164)	NC score	0.010734 (rank : 126)
Query Neighborhood Hits	171	Target Neighborhood Hits	354	Shared Neighborhood Hits	9
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RP1L1_HUMAN
θ value	8.99809 (rank : 165)	NC score	0.012099 (rank : 120)
Query Neighborhood Hits	171	Target Neighborhood Hits	1072	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RPGF4_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.004921 (rank : 150)
Query Neighborhood Hits	171	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.005459 (rank : 148)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

SFPQ_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.003283 (rank : 155)
Query Neighborhood Hits	171	Target Neighborhood Hits	986	Shared Neighborhood Hits	18
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SP6_HUMAN
θ value	8.99809 (rank : 169)	NC score	-0.001879 (rank : 173)
Query Neighborhood Hits	171	Target Neighborhood Hits	700	Shared Neighborhood Hits	10
SwissProt Accessions	Q3SY56	Gene names	SP6, KLF14
Domain Architecture	No domain graphic available
Description	Transcription factor Sp6 (Krueppel-like factor 14).

TNR6A_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.008453 (rank : 138)
Query Neighborhood Hits	171	Target Neighborhood Hits	343	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

TXLNB_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.002821 (rank : 157)
Query Neighborhood Hits	171	Target Neighborhood Hits	640	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

BRAP_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.062169 (rank : 79)
Query Neighborhood Hits	171	Target Neighborhood Hits	560	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.071361 (rank : 76)
Query Neighborhood Hits	171	Target Neighborhood Hits	409	Shared Neighborhood Hits	21
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

Hits sorted by NC score

USP9X_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	171	Target Neighborhood Hits	171	Shared Neighborhood Hits	171
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9X_HUMAN
NC score	0.998198 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	171	Target Neighborhood Hits	161	Shared Neighborhood Hits	148
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9Y_HUMAN
NC score	0.994715 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	171	Target Neighborhood Hits	109	Shared Neighborhood Hits	89
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP24_HUMAN
NC score	0.932613 (rank : 4)	θ value	4.52334e-185 (rank : 4)
Query Neighborhood Hits	171	Target Neighborhood Hits	96	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP34_MOUSE
NC score	0.806973 (rank : 5)	θ value	1.2325e-65 (rank : 6)
Query Neighborhood Hits	171	Target Neighborhood Hits	189	Shared Neighborhood Hits	71
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_HUMAN
NC score	0.806638 (rank : 6)	θ value	1.90147e-66 (rank : 5)
Query Neighborhood Hits	171	Target Neighborhood Hits	210	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP7_HUMAN
NC score	0.782991 (rank : 7)	θ value	3.87602e-27 (rank : 11)
Query Neighborhood Hits	171	Target Neighborhood Hits	93	Shared Neighborhood Hits	71
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP48_HUMAN
NC score	0.776188 (rank : 8)	θ value	3.3877e-31 (rank : 7)
Query Neighborhood Hits	171	Target Neighborhood Hits	101	Shared Neighborhood Hits	74
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP40_HUMAN
NC score	0.772734 (rank : 9)	θ value	4.43474e-23 (rank : 12)
Query Neighborhood Hits	171	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP48_MOUSE
NC score	0.772566 (rank : 10)	θ value	3.74554e-30 (rank : 9)
Query Neighborhood Hits	171	Target Neighborhood Hits	124	Shared Neighborhood Hits	74
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP47_MOUSE
NC score	0.756514 (rank : 11)	θ value	3.74554e-30 (rank : 8)
Query Neighborhood Hits	171	Target Neighborhood Hits	135	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_HUMAN
NC score	0.753572 (rank : 12)	θ value	4.89182e-30 (rank : 10)
Query Neighborhood Hits	171	Target Neighborhood Hits	149	Shared Neighborhood Hits	72
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP46_HUMAN
NC score	0.716360 (rank : 13)	θ value	3.07829e-16 (rank : 18)
Query Neighborhood Hits	171	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.716360 (rank : 14)	θ value	3.07829e-16 (rank : 19)
Query Neighborhood Hits	171	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP12_HUMAN
NC score	0.715011 (rank : 15)	θ value	1.058e-16 (rank : 16)
Query Neighborhood Hits	171	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP18_HUMAN
NC score	0.707125 (rank : 16)	θ value	3.89403e-11 (rank : 34)
Query Neighborhood Hits	171	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UB17L_HUMAN
NC score	0.698266 (rank : 17)	θ value	3.07829e-16 (rank : 17)
Query Neighborhood Hits	171	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBPW_MOUSE
NC score	0.693882 (rank : 18)	θ value	5.43371e-13 (rank : 28)
Query Neighborhood Hits	171	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP36_HUMAN
NC score	0.693640 (rank : 19)	θ value	4.74913e-17 (rank : 15)
Query Neighborhood Hits	171	Target Neighborhood Hits	232	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP22_HUMAN
NC score	0.671946 (rank : 20)	θ value	4.44505e-15 (rank : 21)
Query Neighborhood Hits	171	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP18_MOUSE
NC score	0.670948 (rank : 21)	θ value	8.11959e-09 (rank : 40)
Query Neighborhood Hits	171	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP22_MOUSE
NC score	0.670359 (rank : 22)	θ value	7.58209e-15 (rank : 22)
Query Neighborhood Hits	171	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
NC score	0.663577 (rank : 23)	θ value	1.86753e-13 (rank : 25)
Query Neighborhood Hits	171	Target Neighborhood Hits	162	Shared Neighborhood Hits	73
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP42_HUMAN
NC score	0.659759 (rank : 24)	θ value	7.58209e-15 (rank : 23)
Query Neighborhood Hits	171	Target Neighborhood Hits	445	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP3_MOUSE
NC score	0.659473 (rank : 25)	θ value	9.90251e-15 (rank : 24)
Query Neighborhood Hits	171	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP3_HUMAN
NC score	0.657958 (rank : 26)	θ value	1.99529e-15 (rank : 20)
Query Neighborhood Hits	171	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP20_HUMAN
NC score	0.652802 (rank : 27)	θ value	7.09661e-13 (rank : 29)
Query Neighborhood Hits	171	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP8_MOUSE
NC score	0.648673 (rank : 28)	θ value	2.7842e-17 (rank : 14)
Query Neighborhood Hits	171	Target Neighborhood Hits	362	Shared Neighborhood Hits	76
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP33_HUMAN
NC score	0.646166 (rank : 29)	θ value	2.43908e-13 (rank : 26)
Query Neighborhood Hits	171	Target Neighborhood Hits	157	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP50_MOUSE
NC score	0.645946 (rank : 30)	θ value	8.11959e-09 (rank : 41)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP49_HUMAN
NC score	0.631254 (rank : 31)	θ value	2.43908e-13 (rank : 27)
Query Neighborhood Hits	171	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP2_HUMAN
NC score	0.631089 (rank : 32)	θ value	3.29651e-10 (rank : 35)
Query Neighborhood Hits	171	Target Neighborhood Hits	84	Shared Neighborhood Hits	73
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP44_HUMAN
NC score	0.629282 (rank : 33)	θ value	1.33837e-11 (rank : 32)
Query Neighborhood Hits	171	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP49_MOUSE
NC score	0.628022 (rank : 34)	θ value	1.2105e-12 (rank : 30)
Query Neighborhood Hits	171	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP2_MOUSE
NC score	0.627814 (rank : 35)	θ value	2.79066e-09 (rank : 38)
Query Neighborhood Hits	171	Target Neighborhood Hits	86	Shared Neighborhood Hits	74
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP50_HUMAN
NC score	0.621819 (rank : 36)	θ value	1.53129e-07 (rank : 50)
Query Neighborhood Hits	171	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP8_HUMAN
NC score	0.616122 (rank : 37)	θ value	7.32683e-18 (rank : 13)
Query Neighborhood Hits	171	Target Neighborhood Hits	751	Shared Neighborhood Hits	82
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP21_MOUSE
NC score	0.610652 (rank : 38)	θ value	5.26297e-08 (rank : 47)
Query Neighborhood Hits	171	Target Neighborhood Hits	101	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP21_HUMAN
NC score	0.608805 (rank : 39)	θ value	1.53129e-07 (rank : 49)
Query Neighborhood Hits	171	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP16_HUMAN
NC score	0.594202 (rank : 40)	θ value	1.53129e-07 (rank : 48)
Query Neighborhood Hits	171	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP38_HUMAN
NC score	0.572375 (rank : 41)	θ value	3.29651e-10 (rank : 36)
Query Neighborhood Hits	171	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP35_HUMAN
NC score	0.559494 (rank : 42)	θ value	0.000602161 (rank : 63)
Query Neighborhood Hits	171	Target Neighborhood Hits	223	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP38_MOUSE
NC score	0.558716 (rank : 43)	θ value	1.63604e-09 (rank : 37)
Query Neighborhood Hits	171	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP15_HUMAN
NC score	0.558561 (rank : 44)	θ value	1.33837e-11 (rank : 31)
Query Neighborhood Hits	171	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
NC score	0.558442 (rank : 45)	θ value	1.74796e-11 (rank : 33)
Query Neighborhood Hits	171	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP11_HUMAN
NC score	0.555236 (rank : 46)	θ value	1.06045e-08 (rank : 42)
Query Neighborhood Hits	171	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP14_HUMAN
NC score	0.552981 (rank : 47)	θ value	5.81887e-07 (rank : 52)
Query Neighborhood Hits	171	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP31_HUMAN
NC score	0.549709 (rank : 48)	θ value	1.80886e-08 (rank : 46)
Query Neighborhood Hits	171	Target Neighborhood Hits	293	Shared Neighborhood Hits	75
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP1_HUMAN
NC score	0.547390 (rank : 49)	θ value	0.00035302 (rank : 61)
Query Neighborhood Hits	171	Target Neighborhood Hits	259	Shared Neighborhood Hits	75
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP10_HUMAN
NC score	0.541484 (rank : 50)	θ value	4.76016e-09 (rank : 39)
Query Neighborhood Hits	171	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP43_MOUSE
NC score	0.541326 (rank : 51)	θ value	1.69304e-06 (rank : 56)
Query Neighborhood Hits	171	Target Neighborhood Hits	130	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP10_MOUSE
NC score	0.538301 (rank : 52)	θ value	1.80886e-08 (rank : 45)
Query Neighborhood Hits	171	Target Neighborhood Hits	150	Shared Neighborhood Hits	70
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP43_HUMAN
NC score	0.537326 (rank : 53)	θ value	4.45536e-07 (rank : 51)
Query Neighborhood Hits	171	Target Neighborhood Hits	144	Shared Neighborhood Hits	76
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP4_HUMAN
NC score	0.534718 (rank : 54)	θ value	1.69304e-06 (rank : 57)
Query Neighborhood Hits	171	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP4_MOUSE
NC score	0.533549 (rank : 55)	θ value	1.69304e-06 (rank : 58)
Query Neighborhood Hits	171	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP14_MOUSE
NC score	0.517489 (rank : 56)	θ value	9.92553e-07 (rank : 53)
Query Neighborhood Hits	171	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP37_HUMAN
NC score	0.485707 (rank : 57)	θ value	0.00035302 (rank : 62)
Query Neighborhood Hits	171	Target Neighborhood Hits	208	Shared Neighborhood Hits	77
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP28_MOUSE
NC score	0.472004 (rank : 58)	θ value	1.06045e-08 (rank : 43)
Query Neighborhood Hits	171	Target Neighborhood Hits	178	Shared Neighborhood Hits	73
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_HUMAN
NC score	0.471263 (rank : 59)	θ value	1.38499e-08 (rank : 44)
Query Neighborhood Hits	171	Target Neighborhood Hits	117	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

SNUT2_MOUSE
NC score	0.463275 (rank : 60)	θ value	1.43324e-05 (rank : 59)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBP30_HUMAN
NC score	0.455541 (rank : 61)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	171	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

SNUT2_HUMAN
NC score	0.453644 (rank : 62)	θ value	2.44474e-05 (rank : 60)
Query Neighborhood Hits	171	Target Neighborhood Hits	79	Shared Neighborhood Hits	59
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP25_MOUSE
NC score	0.450933 (rank : 63)	θ value	1.29631e-06 (rank : 55)
Query Neighborhood Hits	171	Target Neighborhood Hits	116	Shared Neighborhood Hits	72
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP25_HUMAN
NC score	0.449796 (rank : 64)	θ value	9.92553e-07 (rank : 54)
Query Neighborhood Hits	171	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP32_HUMAN
NC score	0.427352 (rank : 65)	θ value	0.00175202 (rank : 64)
Query Neighborhood Hits	171	Target Neighborhood Hits	170	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP29_HUMAN
NC score	0.408163 (rank : 66)	θ value	0.0563607 (rank : 73)
Query Neighborhood Hits	171	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP5_MOUSE
NC score	0.398272 (rank : 67)	θ value	0.00228821 (rank : 66)
Query Neighborhood Hits	171	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP6_HUMAN
NC score	0.397872 (rank : 68)	θ value	0.0193708 (rank : 71)
Query Neighborhood Hits	171	Target Neighborhood Hits	188	Shared Neighborhood Hits	78
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP5_HUMAN
NC score	0.396172 (rank : 69)	θ value	0.00228821 (rank : 65)
Query Neighborhood Hits	171	Target Neighborhood Hits	109	Shared Neighborhood Hits	73
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP26_HUMAN
NC score	0.381735 (rank : 70)	θ value	0.00665767 (rank : 68)
Query Neighborhood Hits	171	Target Neighborhood Hits	108	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP13_HUMAN
NC score	0.377098 (rank : 71)	θ value	0.00509761 (rank : 67)
Query Neighborhood Hits	171	Target Neighborhood Hits	99	Shared Neighborhood Hits	72
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP29_MOUSE
NC score	0.376220 (rank : 72)	θ value	0.163984 (rank : 78)
Query Neighborhood Hits	171	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP26_MOUSE
NC score	0.332182 (rank : 73)	θ value	0.0193708 (rank : 70)
Query Neighborhood Hits	171	Target Neighborhood Hits	107	Shared Neighborhood Hits	72
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

PRP5_HUMAN
NC score	0.097307 (rank : 74)	θ value	0.47712 (rank : 85)
Query Neighborhood Hits	171	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
NC score	0.092917 (rank : 75)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	171	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

BRAP_MOUSE
NC score	0.071361 (rank : 76)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	171	Target Neighborhood Hits	409	Shared Neighborhood Hits	21
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CHRC1_HUMAN
NC score	0.069656 (rank : 77)	θ value	0.365318 (rank : 80)
Query Neighborhood Hits	171	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRG0	Gene names	CHRAC1, CHRAC15
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15).

PRP1_HUMAN
NC score	0.062289 (rank : 78)	θ value	0.0113563 (rank : 69)
Query Neighborhood Hits	171	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

BRAP_HUMAN
NC score	0.062169 (rank : 79)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	171	Target Neighborhood Hits	560	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

CCDC9_HUMAN
NC score	0.055527 (rank : 80)	θ value	0.0961366 (rank : 75)
Query Neighborhood Hits	171	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

PRB3_HUMAN
NC score	0.048162 (rank : 81)	θ value	0.0736092 (rank : 74)
Query Neighborhood Hits	171	Target Neighborhood Hits	318	Shared Neighborhood Hits	18
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
NC score	0.047752 (rank : 82)	θ value	0.163984 (rank : 77)
Query Neighborhood Hits	171	Target Neighborhood Hits	330	Shared Neighborhood Hits	17
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

MADCA_HUMAN
NC score	0.046042 (rank : 83)	θ value	0.47712 (rank : 84)
Query Neighborhood Hits	171	Target Neighborhood Hits	221	Shared Neighborhood Hits	9
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

NEIL3_HUMAN
NC score	0.041046 (rank : 84)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	171	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

CI126_HUMAN
NC score	0.034595 (rank : 85)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	171	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N9R8, Q5T163, Q8N1I4	Gene names	C9orf126
Domain Architecture	No domain graphic available
Description	Protein C9orf126.

CI126_MOUSE
NC score	0.034579 (rank : 86)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	171	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C8N2, Q8C409, Q8C8K2	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf126 homolog.

CF211_HUMAN
NC score	0.031916 (rank : 87)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	171	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H993, Q96FC6, Q9UFY5	Gene names	C6orf211
Domain Architecture	No domain graphic available
Description	UPF0364 protein C6orf211.

TR13C_HUMAN
NC score	0.031750 (rank : 88)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	171	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RJ3	Gene names	TNFRSF13C, BAFFR, BR3
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13C (B cell- activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (CD268 antigen).

BCL7C_MOUSE
NC score	0.031266 (rank : 89)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	171	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

BIRC6_HUMAN
NC score	0.031155 (rank : 90)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	171	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

LIX1_MOUSE
NC score	0.031058 (rank : 91)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	171	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P566, Q8VHY1, Q9CYH4	Gene names	Lix1
Domain Architecture	No domain graphic available
Description	Protein limb expression 1 homolog.

OGFR_MOUSE
NC score	0.029172 (rank : 92)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	171	Target Neighborhood Hits	584	Shared Neighborhood Hits	25
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

SYN3_HUMAN
NC score	0.027818 (rank : 93)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	171	Target Neighborhood Hits	203	Shared Neighborhood Hits	6
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

CREB5_HUMAN
NC score	0.026233 (rank : 94)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	171	Target Neighborhood Hits	222	Shared Neighborhood Hits	11
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

SGOL1_MOUSE
NC score	0.025687 (rank : 95)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	171	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CXH7, Q3U4K4, Q588H1, Q8BKW2	Gene names	Sgol1, Sgo1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1.

PRR6_HUMAN
NC score	0.025399 (rank : 96)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	171	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z7K6, Q3L8N5, Q8NFH6	Gene names	PRR6
Domain Architecture	No domain graphic available
Description	Proline-rich protein 6 (Nuclear protein p30).

IPP1_MOUSE
NC score	0.024349 (rank : 97)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	171	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERT9	Gene names	Ppp1r1a
Domain Architecture
Description	Protein phosphatase inhibitor 1 (IPP-1) (I-1).

CS007_HUMAN
NC score	0.023385 (rank : 98)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	171	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

DMD_MOUSE
NC score	0.022772 (rank : 99)	θ value	0.0252991 (rank : 72)
Query Neighborhood Hits	171	Target Neighborhood Hits	1111	Shared Neighborhood Hits	23
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

IMMT_HUMAN
NC score	0.021925 (rank : 100)	θ value	0.0961366 (rank : 76)
Query Neighborhood Hits	171	Target Neighborhood Hits	494	Shared Neighborhood Hits	10
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

CALX_HUMAN
NC score	0.021680 (rank : 101)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	171	Target Neighborhood Hits	96	Shared Neighborhood Hits	13
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

CU013_HUMAN
NC score	0.020165 (rank : 102)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	171	Target Neighborhood Hits	405	Shared Neighborhood Hits	9
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

H6ST3_HUMAN
NC score	0.019432 (rank : 103)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	171	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZP7, Q5W0L0, Q68CW6	Gene names	HS6ST3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3).

SYN1_MOUSE
NC score	0.016645 (rank : 104)	θ value	1.06291 (rank : 89)
Query Neighborhood Hits	171	Target Neighborhood Hits	363	Shared Neighborhood Hits	11
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

NCOA4_HUMAN
NC score	0.016590 (rank : 105)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	171	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q13772, Q14239	Gene names	NCOA4, ARA70, ELE1, RFG
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 4 (NCoA-4) (70 kDa androgen receptor coactivator) (70 kDa AR-activator) (Ret-activating protein ELE1).

NUFP2_MOUSE
NC score	0.016256 (rank : 106)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	171	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q5F2E7, Q3TCE2, Q3V195, Q80TF1	Gene names	Nufip2, Kiaa1321
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 2 (FMRP- interacting protein 2) (82 kDa FMRP-interacting protein) (82-FIP).

SYNE1_HUMAN
NC score	0.016247 (rank : 107)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	171	Target Neighborhood Hits	1484	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

GON4L_MOUSE
NC score	0.015790 (rank : 108)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	171	Target Neighborhood Hits	455	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

HRG_HUMAN
NC score	0.015325 (rank : 109)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	171	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	P04196	Gene names	HRG
Domain Architecture
Description	Histidine-rich glycoprotein precursor (Histidine-proline-rich glycoprotein) (HPRG).

FA47A_HUMAN
NC score	0.014548 (rank : 110)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	171	Target Neighborhood Hits	451	Shared Neighborhood Hits	19
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

SMC2_MOUSE
NC score	0.014057 (rank : 111)	θ value	0.47712 (rank : 86)
Query Neighborhood Hits	171	Target Neighborhood Hits	1131	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

PDZD8_HUMAN
NC score	0.014037 (rank : 112)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	171	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

ARY1_MOUSE
NC score	0.013488 (rank : 113)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	171	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P50294	Gene names	Nat1, Aac1
Domain Architecture
Description	Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (N-acetyltransferase type 1) (NAT-1).

FRAP_MOUSE
NC score	0.013217 (rank : 114)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	171	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_HUMAN
NC score	0.013216 (rank : 115)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	171	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

PAIP1_HUMAN
NC score	0.013214 (rank : 116)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	171	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

GCM1_HUMAN
NC score	0.013184 (rank : 117)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	171	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NP62, Q5T0X0, Q99468, Q9P1X3	Gene names	GCM1, GCMA
Domain Architecture
Description	Chorion-specific transcription factor GCMa (Glial cells missing homolog 1) (GCM motif protein 1) (hGCMa).

MAGI2_HUMAN
NC score	0.013020 (rank : 118)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	171	Target Neighborhood Hits	373	Shared Neighborhood Hits	11
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

EMIL2_MOUSE
NC score	0.012930 (rank : 119)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	171	Target Neighborhood Hits	485	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

RP1L1_HUMAN
NC score	0.012099 (rank : 120)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	171	Target Neighborhood Hits	1072	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MINT_MOUSE
NC score	0.011259 (rank : 121)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	171	Target Neighborhood Hits	1514	Shared Neighborhood Hits	34
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ENAM_HUMAN
NC score	0.011162 (rank : 122)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	171	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

AMBN_HUMAN
NC score	0.011072 (rank : 123)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	171	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP70, Q9H2X1, Q9H4L1	Gene names	AMBN
Domain Architecture
Description	Ameloblastin precursor.

BLNK_HUMAN
NC score	0.010925 (rank : 124)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	171	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

CAF1B_MOUSE
NC score	0.010740 (rank : 125)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	171	Target Neighborhood Hits	385	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

PPRB_MOUSE
NC score	0.010734 (rank : 126)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	171	Target Neighborhood Hits	354	Shared Neighborhood Hits	9
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

CAC1B_HUMAN
NC score	0.010386 (rank : 127)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	171	Target Neighborhood Hits	257	Shared Neighborhood Hits	10
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

DMD_HUMAN
NC score	0.009889 (rank : 128)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	171	Target Neighborhood Hits	1135	Shared Neighborhood Hits	18
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DONS_HUMAN
NC score	0.009681 (rank : 129)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	171	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYP3, Q9NSR9, Q9NVZ5, Q9NYP1, Q9NYP2	Gene names	DONSON, C21orf60
Domain Architecture	No domain graphic available
Description	Protein downstream neighbor of Son (B17).

MINT_HUMAN
NC score	0.009602 (rank : 130)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	171	Target Neighborhood Hits	1291	Shared Neighborhood Hits	22
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

H6ST3_MOUSE
NC score	0.009572 (rank : 131)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	171	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QYK4	Gene names	Hs6st3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3) (mHS6ST- 3).

MAGI2_MOUSE
NC score	0.009477 (rank : 132)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	171	Target Neighborhood Hits	370	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

BPTF_HUMAN
NC score	0.009395 (rank : 133)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	171	Target Neighborhood Hits	786	Shared Neighborhood Hits	12
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

SFPQ_MOUSE
NC score	0.009129 (rank : 134)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	171	Target Neighborhood Hits	958	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

MLL2_HUMAN
NC score	0.008865 (rank : 135)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	171	Target Neighborhood Hits	1788	Shared Neighborhood Hits	43
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ZN409_HUMAN
NC score	0.008552 (rank : 136)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	171	Target Neighborhood Hits	842	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

BRD4_HUMAN
NC score	0.008485 (rank : 137)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	171	Target Neighborhood Hits	851	Shared Neighborhood Hits	25
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

TNR6A_HUMAN
NC score	0.008453 (rank : 138)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	171	Target Neighborhood Hits	343	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

PHF10_HUMAN
NC score	0.008403 (rank : 139)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	171	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

AFF2_MOUSE
NC score	0.008298 (rank : 140)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	171	Target Neighborhood Hits	225	Shared Neighborhood Hits	6
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

FGD6_MOUSE
NC score	0.008126 (rank : 141)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	171	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

AN13B_MOUSE
NC score	0.007916 (rank : 142)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	171	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

EMID1_MOUSE
NC score	0.007583 (rank : 143)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	171	Target Neighborhood Hits	230	Shared Neighborhood Hits	9
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

FGD6_HUMAN
NC score	0.007376 (rank : 144)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	171	Target Neighborhood Hits	237	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

COBA1_MOUSE
NC score	0.007238 (rank : 145)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	171	Target Neighborhood Hits	487	Shared Neighborhood Hits	22
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

KIFC2_HUMAN
NC score	0.007133 (rank : 146)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	171	Target Neighborhood Hits	237	Shared Neighborhood Hits	8
SwissProt Accessions	Q96AC6	Gene names	KIFC2
Domain Architecture
Description	Kinesin-like protein KIFC2.

JADE3_MOUSE
NC score	0.006554 (rank : 147)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	171	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

RPGF4_MOUSE
NC score	0.005459 (rank : 148)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

EHD4_HUMAN
NC score	0.005236 (rank : 149)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	171	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H223, Q9HAR1, Q9NZN2	Gene names	EHD4, HCA10, HCA11
Domain Architecture
Description	EH-domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11).

RPGF4_HUMAN
NC score	0.004921 (rank : 150)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	171	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

CAH9_HUMAN
NC score	0.004540 (rank : 151)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	171	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q16790	Gene names	CA9, G250, MN
Domain Architecture
Description	Carbonic anhydrase 9 precursor (EC 4.2.1.1) (Carbonic anhydrase IX) (Carbonate dehydratase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC- associated antigen G250) (pMW1).

WDR33_HUMAN
NC score	0.004055 (rank : 152)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	171	Target Neighborhood Hits	638	Shared Neighborhood Hits	17
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

MIB2_HUMAN
NC score	0.003669 (rank : 153)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	171	Target Neighborhood Hits	438	Shared Neighborhood Hits	8
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

CAC1C_MOUSE
NC score	0.003632 (rank : 154)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	171	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

SFPQ_HUMAN
NC score	0.003283 (rank : 155)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	171	Target Neighborhood Hits	986	Shared Neighborhood Hits	18
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

HCN2_HUMAN
NC score	0.003221 (rank : 156)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	171	Target Neighborhood Hits	369	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

TXLNB_MOUSE
NC score	0.002821 (rank : 157)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	171	Target Neighborhood Hits	640	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

SALL2_MOUSE
NC score	0.002763 (rank : 158)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	171	Target Neighborhood Hits	836	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

NIN_MOUSE
NC score	0.002376 (rank : 159)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	171	Target Neighborhood Hits	1376	Shared Neighborhood Hits	21
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

CENG1_MOUSE
NC score	0.001641 (rank : 160)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	171	Target Neighborhood Hits	531	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

RTN4R_HUMAN
NC score	0.001357 (rank : 161)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	171	Target Neighborhood Hits	271	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZR6	Gene names	RTN4R, NOGOR
Domain Architecture
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

MYH13_HUMAN
NC score	0.001282 (rank : 162)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	171	Target Neighborhood Hits	1504	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

ATBF1_HUMAN
NC score	0.001278 (rank : 163)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	171	Target Neighborhood Hits	1547	Shared Neighborhood Hits	14
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

SALL2_HUMAN
NC score	0.000707 (rank : 164)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	171	Target Neighborhood Hits	835	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

LRC40_MOUSE
NC score	0.000667 (rank : 165)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	171	Target Neighborhood Hits	311	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CRC8, Q78WQ9, Q8BS83	Gene names	Lrrc40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

ADA29_HUMAN
NC score	0.000053 (rank : 166)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	171	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

SP6_MOUSE
NC score	0.000021 (rank : 167)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	171	Target Neighborhood Hits	704	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ESX2, Q6VM22	Gene names	Sp6, Epfn, Klf14
Domain Architecture	No domain graphic available
Description	Transcription factor Sp6 (Krueppel-like factor 14) (Epiprofin).

LRC8D_MOUSE
NC score	-0.000277 (rank : 168)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	171	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGR2, Q3UVA9, Q8CI13	Gene names	Lrrc8d, Lrrc5
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8D.

ACK1_HUMAN
NC score	-0.001165 (rank : 169)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	171	Target Neighborhood Hits	1140	Shared Neighborhood Hits	22
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

RYK_HUMAN
NC score	-0.001206 (rank : 170)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	171	Target Neighborhood Hits	701	Shared Neighborhood Hits	5
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
NC score	-0.001368 (rank : 171)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	171	Target Neighborhood Hits	715	Shared Neighborhood Hits	5
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

KS6C1_MOUSE
NC score	-0.001659 (rank : 172)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	171	Target Neighborhood Hits	700	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

SP6_HUMAN
NC score	-0.001879 (rank : 173)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	171	Target Neighborhood Hits	700	Shared Neighborhood Hits	10
SwissProt Accessions	Q3SY56	Gene names	SP6, KLF14
Domain Architecture	No domain graphic available
Description	Transcription factor Sp6 (Krueppel-like factor 14).