Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : UBP25_HUMAN

For an explanation of this page, click here

UBP25_HUMAN
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP25_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	124	Target Neighborhood Hits	124	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP25_MOUSE
θ value	0 (rank : 2)	NC score	0.994649 (rank : 2)
Query Neighborhood Hits	124	Target Neighborhood Hits	116	Shared Neighborhood Hits	95
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP28_HUMAN
θ value	0 (rank : 3)	NC score	0.974591 (rank : 3)
Query Neighborhood Hits	124	Target Neighborhood Hits	117	Shared Neighborhood Hits	75
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_MOUSE
θ value	0 (rank : 4)	NC score	0.966771 (rank : 4)
Query Neighborhood Hits	124	Target Neighborhood Hits	178	Shared Neighborhood Hits	76
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP48_HUMAN
θ value	2.97466e-19 (rank : 5)	NC score	0.585316 (rank : 5)
Query Neighborhood Hits	124	Target Neighborhood Hits	101	Shared Neighborhood Hits	72
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
θ value	1.92812e-18 (rank : 6)	NC score	0.581865 (rank : 6)
Query Neighborhood Hits	124	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP34_HUMAN
θ value	3.29651e-10 (rank : 7)	NC score	0.492418 (rank : 8)
Query Neighborhood Hits	124	Target Neighborhood Hits	210	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP7_HUMAN
θ value	3.29651e-10 (rank : 8)	NC score	0.536544 (rank : 7)
Query Neighborhood Hits	124	Target Neighborhood Hits	93	Shared Neighborhood Hits	69
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP34_MOUSE
θ value	4.30538e-10 (rank : 9)	NC score	0.491152 (rank : 10)
Query Neighborhood Hits	124	Target Neighborhood Hits	189	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

USP9X_HUMAN
θ value	1.06045e-08 (rank : 10)	NC score	0.461587 (rank : 22)
Query Neighborhood Hits	124	Target Neighborhood Hits	161	Shared Neighborhood Hits	73
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

UBP37_HUMAN
θ value	1.38499e-08 (rank : 11)	NC score	0.420795 (rank : 25)
Query Neighborhood Hits	124	Target Neighborhood Hits	208	Shared Neighborhood Hits	78
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP35_HUMAN
θ value	6.87365e-08 (rank : 12)	NC score	0.490010 (rank : 12)
Query Neighborhood Hits	124	Target Neighborhood Hits	223	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP46_HUMAN
θ value	6.87365e-08 (rank : 13)	NC score	0.486854 (rank : 13)
Query Neighborhood Hits	124	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	6.87365e-08 (rank : 14)	NC score	0.486854 (rank : 14)
Query Neighborhood Hits	124	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP47_MOUSE
θ value	1.53129e-07 (rank : 15)	NC score	0.490992 (rank : 11)
Query Neighborhood Hits	124	Target Neighborhood Hits	135	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_HUMAN
θ value	1.99992e-07 (rank : 16)	NC score	0.491565 (rank : 9)
Query Neighborhood Hits	124	Target Neighborhood Hits	149	Shared Neighborhood Hits	70
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

USP9Y_HUMAN
θ value	1.99992e-07 (rank : 17)	NC score	0.457512 (rank : 23)
Query Neighborhood Hits	124	Target Neighborhood Hits	109	Shared Neighborhood Hits	72
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP38_MOUSE
θ value	5.81887e-07 (rank : 18)	NC score	0.469797 (rank : 20)
Query Neighborhood Hits	124	Target Neighborhood Hits	100	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP38_HUMAN
θ value	7.59969e-07 (rank : 19)	NC score	0.469961 (rank : 19)
Query Neighborhood Hits	124	Target Neighborhood Hits	97	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

USP9X_MOUSE
θ value	9.92553e-07 (rank : 20)	NC score	0.449796 (rank : 24)
Query Neighborhood Hits	124	Target Neighborhood Hits	171	Shared Neighborhood Hits	73
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP18_MOUSE
θ value	1.69304e-06 (rank : 21)	NC score	0.484858 (rank : 15)
Query Neighborhood Hits	124	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP12_HUMAN
θ value	3.77169e-06 (rank : 22)	NC score	0.468892 (rank : 21)
Query Neighborhood Hits	124	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP24_HUMAN
θ value	1.87187e-05 (rank : 23)	NC score	0.477483 (rank : 18)
Query Neighborhood Hits	124	Target Neighborhood Hits	96	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP18_HUMAN
θ value	4.1701e-05 (rank : 24)	NC score	0.483497 (rank : 17)
Query Neighborhood Hits	124	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP3_MOUSE
θ value	9.29e-05 (rank : 25)	NC score	0.411085 (rank : 26)
Query Neighborhood Hits	124	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP16_HUMAN
θ value	0.000270298 (rank : 26)	NC score	0.408513 (rank : 27)
Query Neighborhood Hits	124	Target Neighborhood Hits	126	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP49_HUMAN
θ value	0.000602161 (rank : 27)	NC score	0.387974 (rank : 37)
Query Neighborhood Hits	124	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP2_MOUSE
θ value	0.000786445 (rank : 28)	NC score	0.390700 (rank : 36)
Query Neighborhood Hits	124	Target Neighborhood Hits	86	Shared Neighborhood Hits	72
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP33_HUMAN
θ value	0.000786445 (rank : 29)	NC score	0.404974 (rank : 28)
Query Neighborhood Hits	124	Target Neighborhood Hits	157	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP3_HUMAN
θ value	0.000786445 (rank : 30)	NC score	0.394454 (rank : 32)
Query Neighborhood Hits	124	Target Neighborhood Hits	88	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP40_HUMAN
θ value	0.00134147 (rank : 31)	NC score	0.483725 (rank : 16)
Query Neighborhood Hits	124	Target Neighborhood Hits	81	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP14_HUMAN
θ value	0.00298849 (rank : 32)	NC score	0.395503 (rank : 31)
Query Neighborhood Hits	124	Target Neighborhood Hits	89	Shared Neighborhood Hits	70
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP22_HUMAN
θ value	0.00298849 (rank : 33)	NC score	0.391408 (rank : 34)
Query Neighborhood Hits	124	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
θ value	0.00298849 (rank : 34)	NC score	0.391089 (rank : 35)
Query Neighborhood Hits	124	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP14_MOUSE
θ value	0.00390308 (rank : 35)	NC score	0.384827 (rank : 39)
Query Neighborhood Hits	124	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP49_MOUSE
θ value	0.00390308 (rank : 36)	NC score	0.385822 (rank : 38)
Query Neighborhood Hits	124	Target Neighborhood Hits	91	Shared Neighborhood Hits	72
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP8_MOUSE
θ value	0.00390308 (rank : 37)	NC score	0.379581 (rank : 41)
Query Neighborhood Hits	124	Target Neighborhood Hits	362	Shared Neighborhood Hits	81
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP29_MOUSE
θ value	0.00509761 (rank : 38)	NC score	0.340034 (rank : 53)
Query Neighborhood Hits	124	Target Neighborhood Hits	95	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP13_HUMAN
θ value	0.00665767 (rank : 39)	NC score	0.306401 (rank : 64)
Query Neighborhood Hits	124	Target Neighborhood Hits	99	Shared Neighborhood Hits	71
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP29_HUMAN
θ value	0.00665767 (rank : 40)	NC score	0.344613 (rank : 52)
Query Neighborhood Hits	124	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP26_MOUSE
θ value	0.00869519 (rank : 41)	NC score	0.308053 (rank : 62)
Query Neighborhood Hits	124	Target Neighborhood Hits	107	Shared Neighborhood Hits	69
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP2_HUMAN
θ value	0.0148317 (rank : 42)	NC score	0.380341 (rank : 40)
Query Neighborhood Hits	124	Target Neighborhood Hits	84	Shared Neighborhood Hits	72
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP36_HUMAN
θ value	0.0148317 (rank : 43)	NC score	0.403748 (rank : 30)
Query Neighborhood Hits	124	Target Neighborhood Hits	232	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

MYH10_HUMAN
θ value	0.0193708 (rank : 44)	NC score	0.020607 (rank : 93)
Query Neighborhood Hits	124	Target Neighborhood Hits	1620	Shared Neighborhood Hits	31
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

UBPW_MOUSE
θ value	0.0193708 (rank : 45)	NC score	0.404167 (rank : 29)
Query Neighborhood Hits	124	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP26_HUMAN
θ value	0.0252991 (rank : 46)	NC score	0.324344 (rank : 56)
Query Neighborhood Hits	124	Target Neighborhood Hits	108	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP30_HUMAN
θ value	0.0252991 (rank : 47)	NC score	0.392736 (rank : 33)
Query Neighborhood Hits	124	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP8_HUMAN
θ value	0.0330416 (rank : 48)	NC score	0.357158 (rank : 49)
Query Neighborhood Hits	124	Target Neighborhood Hits	751	Shared Neighborhood Hits	88
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

MYH10_MOUSE
θ value	0.0563607 (rank : 49)	NC score	0.019459 (rank : 94)
Query Neighborhood Hits	124	Target Neighborhood Hits	1612	Shared Neighborhood Hits	28
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

UBP4_MOUSE
θ value	0.0563607 (rank : 50)	NC score	0.318119 (rank : 57)
Query Neighborhood Hits	124	Target Neighborhood Hits	90	Shared Neighborhood Hits	72
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP51_HUMAN
θ value	0.0563607 (rank : 51)	NC score	0.376659 (rank : 43)
Query Neighborhood Hits	124	Target Neighborhood Hits	162	Shared Neighborhood Hits	72
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP6_HUMAN
θ value	0.0563607 (rank : 52)	NC score	0.265719 (rank : 71)
Query Neighborhood Hits	124	Target Neighborhood Hits	188	Shared Neighborhood Hits	74
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP10_MOUSE
θ value	0.0736092 (rank : 53)	NC score	0.297859 (rank : 65)
Query Neighborhood Hits	124	Target Neighborhood Hits	150	Shared Neighborhood Hits	68
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP43_HUMAN
θ value	0.0736092 (rank : 54)	NC score	0.324816 (rank : 55)
Query Neighborhood Hits	124	Target Neighborhood Hits	144	Shared Neighborhood Hits	72
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP43_MOUSE
θ value	0.0961366 (rank : 55)	NC score	0.327910 (rank : 54)
Query Neighborhood Hits	124	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP44_HUMAN
θ value	0.0961366 (rank : 56)	NC score	0.367041 (rank : 46)
Query Neighborhood Hits	124	Target Neighborhood Hits	91	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP20_HUMAN
θ value	0.125558 (rank : 57)	NC score	0.378515 (rank : 42)
Query Neighborhood Hits	124	Target Neighborhood Hits	113	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP32_HUMAN
θ value	0.125558 (rank : 58)	NC score	0.276779 (rank : 68)
Query Neighborhood Hits	124	Target Neighborhood Hits	170	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UB17L_HUMAN
θ value	0.163984 (rank : 59)	NC score	0.373663 (rank : 44)
Query Neighborhood Hits	124	Target Neighborhood Hits	83	Shared Neighborhood Hits	71
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP15_HUMAN
θ value	0.163984 (rank : 60)	NC score	0.312415 (rank : 60)
Query Neighborhood Hits	124	Target Neighborhood Hits	92	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
θ value	0.163984 (rank : 61)	NC score	0.312562 (rank : 59)
Query Neighborhood Hits	124	Target Neighborhood Hits	88	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP1_HUMAN
θ value	0.21417 (rank : 62)	NC score	0.350989 (rank : 51)
Query Neighborhood Hits	124	Target Neighborhood Hits	259	Shared Neighborhood Hits	72
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP21_HUMAN
θ value	0.21417 (rank : 63)	NC score	0.360211 (rank : 47)
Query Neighborhood Hits	124	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP21_MOUSE
θ value	0.21417 (rank : 64)	NC score	0.358713 (rank : 48)
Query Neighborhood Hits	124	Target Neighborhood Hits	101	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP10_HUMAN
θ value	0.279714 (rank : 65)	NC score	0.293670 (rank : 66)
Query Neighborhood Hits	124	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

ROCK1_HUMAN
θ value	0.365318 (rank : 66)	NC score	0.010484 (rank : 109)
Query Neighborhood Hits	124	Target Neighborhood Hits	2000	Shared Neighborhood Hits	32
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

UBP5_HUMAN
θ value	0.365318 (rank : 67)	NC score	0.271802 (rank : 70)
Query Neighborhood Hits	124	Target Neighborhood Hits	109	Shared Neighborhood Hits	72
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
θ value	0.365318 (rank : 68)	NC score	0.275249 (rank : 69)
Query Neighborhood Hits	124	Target Neighborhood Hits	106	Shared Neighborhood Hits	72
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

ATX2_HUMAN
θ value	0.47712 (rank : 69)	NC score	0.030374 (rank : 83)
Query Neighborhood Hits	124	Target Neighborhood Hits	375	Shared Neighborhood Hits	4
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CAP2_HUMAN
θ value	0.47712 (rank : 70)	NC score	0.046267 (rank : 75)
Query Neighborhood Hits	124	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P40123, Q6IAY2	Gene names	CAP2
Domain Architecture
Description	Adenylyl cyclase-associated protein 2 (CAP 2).

CASP_HUMAN
θ value	0.47712 (rank : 71)	NC score	0.035279 (rank : 79)
Query Neighborhood Hits	124	Target Neighborhood Hits	1131	Shared Neighborhood Hits	33
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_HUMAN
θ value	0.47712 (rank : 72)	NC score	0.035892 (rank : 77)
Query Neighborhood Hits	124	Target Neighborhood Hits	1574	Shared Neighborhood Hits	34
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

UBP4_HUMAN
θ value	0.47712 (rank : 73)	NC score	0.307989 (rank : 63)
Query Neighborhood Hits	124	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

WEE1B_HUMAN
θ value	0.47712 (rank : 74)	NC score	0.006169 (rank : 118)
Query Neighborhood Hits	124	Target Neighborhood Hits	836	Shared Neighborhood Hits	6
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

CASP_MOUSE
θ value	0.62314 (rank : 75)	NC score	0.035265 (rank : 80)
Query Neighborhood Hits	124	Target Neighborhood Hits	1152	Shared Neighborhood Hits	32
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_MOUSE
θ value	0.62314 (rank : 76)	NC score	0.035436 (rank : 78)
Query Neighborhood Hits	124	Target Neighborhood Hits	1620	Shared Neighborhood Hits	36
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

GON4L_MOUSE
θ value	0.62314 (rank : 77)	NC score	0.023234 (rank : 91)
Query Neighborhood Hits	124	Target Neighborhood Hits	455	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

UBP31_HUMAN
θ value	0.62314 (rank : 78)	NC score	0.310829 (rank : 61)
Query Neighborhood Hits	124	Target Neighborhood Hits	293	Shared Neighborhood Hits	72
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

ROCK1_MOUSE
θ value	0.813845 (rank : 79)	NC score	0.009763 (rank : 110)
Query Neighborhood Hits	124	Target Neighborhood Hits	2126	Shared Neighborhood Hits	33
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SNUT2_HUMAN
θ value	0.813845 (rank : 80)	NC score	0.224873 (rank : 73)
Query Neighborhood Hits	124	Target Neighborhood Hits	79	Shared Neighborhood Hits	58
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

SNUT2_MOUSE
θ value	0.813845 (rank : 81)	NC score	0.231108 (rank : 72)
Query Neighborhood Hits	124	Target Neighborhood Hits	80	Shared Neighborhood Hits	59
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

DZIP1_MOUSE
θ value	1.06291 (rank : 82)	NC score	0.025913 (rank : 85)
Query Neighborhood Hits	124	Target Neighborhood Hits	530	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

OSBP2_MOUSE
θ value	1.06291 (rank : 83)	NC score	0.013334 (rank : 106)
Query Neighborhood Hits	124	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

PCNT_HUMAN
θ value	1.06291 (rank : 84)	NC score	0.024826 (rank : 87)
Query Neighborhood Hits	124	Target Neighborhood Hits	1551	Shared Neighborhood Hits	32
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CAP2_MOUSE
θ value	1.38821 (rank : 85)	NC score	0.041206 (rank : 76)
Query Neighborhood Hits	124	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CYT6, Q80YU7, Q9D6L0	Gene names	Cap2
Domain Architecture
Description	Adenylyl cyclase-associated protein 2 (CAP 2).

KMHN1_MOUSE
θ value	1.38821 (rank : 86)	NC score	0.023876 (rank : 89)
Query Neighborhood Hits	124	Target Neighborhood Hits	949	Shared Neighborhood Hits	29
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

RRMJ3_MOUSE
θ value	1.38821 (rank : 87)	NC score	0.032980 (rank : 82)
Query Neighborhood Hits	124	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

ATX2_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.025410 (rank : 86)
Query Neighborhood Hits	124	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

IF4G3_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.015649 (rank : 104)
Query Neighborhood Hits	124	Target Neighborhood Hits	247	Shared Neighborhood Hits	9
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

K1C9_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.009696 (rank : 111)
Query Neighborhood Hits	124	Target Neighborhood Hits	526	Shared Neighborhood Hits	21
SwissProt Accessions	P35527, O00109, Q14665	Gene names	KRT9
Domain Architecture
Description	Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9).

RYR1_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.016627 (rank : 100)
Query Neighborhood Hits	124	Target Neighborhood Hits	303	Shared Neighborhood Hits	4
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

UBP42_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.354691 (rank : 50)
Query Neighborhood Hits	124	Target Neighborhood Hits	445	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

AT2B3_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.013402 (rank : 105)
Query Neighborhood Hits	124	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q16720, Q12995, Q16858	Gene names	ATP2B3
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 3 (EC 3.6.3.8) (PMCA3) (Plasma membrane calcium pump isoform 3) (Plasma membrane calcium ATPase isoform 3).

ITSN1_HUMAN
θ value	2.36792 (rank : 94)	NC score	0.012746 (rank : 107)
Query Neighborhood Hits	124	Target Neighborhood Hits	1757	Shared Neighborhood Hits	37
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

KIF5A_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.016942 (rank : 98)
Query Neighborhood Hits	124	Target Neighborhood Hits	843	Shared Neighborhood Hits	24
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF5A_MOUSE
θ value	2.36792 (rank : 96)	NC score	0.016741 (rank : 99)
Query Neighborhood Hits	124	Target Neighborhood Hits	859	Shared Neighborhood Hits	25
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

SNCAP_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.011405 (rank : 108)
Query Neighborhood Hits	124	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

UBP50_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.370801 (rank : 45)
Query Neighborhood Hits	124	Target Neighborhood Hits	80	Shared Neighborhood Hits	72
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

HMMR_MOUSE
θ value	3.0926 (rank : 99)	NC score	0.016381 (rank : 102)
Query Neighborhood Hits	124	Target Neighborhood Hits	1178	Shared Neighborhood Hits	26
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

SAS6_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.019383 (rank : 95)
Query Neighborhood Hits	124	Target Neighborhood Hits	791	Shared Neighborhood Hits	22
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

CE152_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.023393 (rank : 90)
Query Neighborhood Hits	124	Target Neighborhood Hits	976	Shared Neighborhood Hits	28
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CENPF_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.018838 (rank : 96)
Query Neighborhood Hits	124	Target Neighborhood Hits	1932	Shared Neighborhood Hits	32
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

GUC2C_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.003854 (rank : 121)
Query Neighborhood Hits	124	Target Neighborhood Hits	624	Shared Neighborhood Hits	6
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

LYST_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.008306 (rank : 115)
Query Neighborhood Hits	124	Target Neighborhood Hits	324	Shared Neighborhood Hits	8
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

ATX3_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.024671 (rank : 88)
Query Neighborhood Hits	124	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	P54252, O15284, O15285, O15286, Q8N189, Q96TC3, Q96TC4, Q9H3N0	Gene names	ATXN3, ATX3, MJD, MJD1, SCA3
Domain Architecture
Description	Ataxin-3 (EC 3.4.22.-) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein).

HXB4_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.004805 (rank : 120)
Query Neighborhood Hits	124	Target Neighborhood Hits	376	Shared Neighborhood Hits	5
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

HXB4_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.004826 (rank : 119)
Query Neighborhood Hits	124	Target Neighborhood Hits	375	Shared Neighborhood Hits	5
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

NOL6_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.033845 (rank : 81)
Query Neighborhood Hits	124	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R5K4, Q6PAN8, Q8C6V4, Q8R5K3, Q8VCG0, Q8WTY7	Gene names	Nol6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

TNIP3_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.020795 (rank : 92)
Query Neighborhood Hits	124	Target Neighborhood Hits	511	Shared Neighborhood Hits	21
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

ATX3_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.026928 (rank : 84)
Query Neighborhood Hits	124	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CVD2	Gene names	Atxn3, Mjd
Domain Architecture
Description	Ataxin-3 (EC 3.4.22.-) (Machado-Joseph disease protein 1 homolog).

ITIH2_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.006666 (rank : 117)
Query Neighborhood Hits	124	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q61703	Gene names	Itih2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2).

KINH_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.016172 (rank : 103)
Query Neighborhood Hits	124	Target Neighborhood Hits	1231	Shared Neighborhood Hits	31
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KINH_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.016526 (rank : 101)
Query Neighborhood Hits	124	Target Neighborhood Hits	1082	Shared Neighborhood Hits	30
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

PIWL3_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.009206 (rank : 114)
Query Neighborhood Hits	124	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z3Z3	Gene names	PIWIL3
Domain Architecture	No domain graphic available
Description	Piwi-like protein 3.

PTC2_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.007353 (rank : 116)
Query Neighborhood Hits	124	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	O35595, Q546T0	Gene names	Ptch2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

UBP11_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.292334 (rank : 67)
Query Neighborhood Hits	124	Target Neighborhood Hits	88	Shared Neighborhood Hits	72
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

ZN694_HUMAN
θ value	6.88961 (rank : 117)	NC score	-0.003758 (rank : 126)
Query Neighborhood Hits	124	Target Neighborhood Hits	764	Shared Neighborhood Hits	4
SwissProt Accessions	Q63HK3, Q6ZN77	Gene names	ZNF694
Domain Architecture	No domain graphic available
Description	Zinc finger protein 694.

FARP1_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.002777 (rank : 124)
Query Neighborhood Hits	124	Target Neighborhood Hits	241	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

PLCB1_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.009466 (rank : 113)
Query Neighborhood Hits	124	Target Neighborhood Hits	614	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PRDM1_MOUSE
θ value	8.99809 (rank : 120)	NC score	-0.002274 (rank : 125)
Query Neighborhood Hits	124	Target Neighborhood Hits	766	Shared Neighborhood Hits	5
SwissProt Accessions	Q60636	Gene names	Prdm1, Blimp1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1).

RFWD2_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.003337 (rank : 123)
Query Neighborhood Hits	124	Target Neighborhood Hits	518	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.003404 (rank : 122)
Query Neighborhood Hits	124	Target Neighborhood Hits	535	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RHG25_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.009583 (rank : 112)
Query Neighborhood Hits	124	Target Neighborhood Hits	550	Shared Neighborhood Hits	26
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SM1L2_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.018227 (rank : 97)
Query Neighborhood Hits	124	Target Neighborhood Hits	918	Shared Neighborhood Hits	30
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

BRAP_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.050387 (rank : 74)
Query Neighborhood Hits	124	Target Neighborhood Hits	409	Shared Neighborhood Hits	32
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

UBP50_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.316467 (rank : 58)
Query Neighborhood Hits	124	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

Hits sorted by NC score

UBP25_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	124	Target Neighborhood Hits	124	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP25_MOUSE
NC score	0.994649 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	124	Target Neighborhood Hits	116	Shared Neighborhood Hits	95
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP28_HUMAN
NC score	0.974591 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	124	Target Neighborhood Hits	117	Shared Neighborhood Hits	75
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_MOUSE
NC score	0.966771 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	124	Target Neighborhood Hits	178	Shared Neighborhood Hits	76
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP48_HUMAN
NC score	0.585316 (rank : 5)	θ value	2.97466e-19 (rank : 5)
Query Neighborhood Hits	124	Target Neighborhood Hits	101	Shared Neighborhood Hits	72
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
NC score	0.581865 (rank : 6)	θ value	1.92812e-18 (rank : 6)
Query Neighborhood Hits	124	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP7_HUMAN
NC score	0.536544 (rank : 7)	θ value	3.29651e-10 (rank : 8)
Query Neighborhood Hits	124	Target Neighborhood Hits	93	Shared Neighborhood Hits	69
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP34_HUMAN
NC score	0.492418 (rank : 8)	θ value	3.29651e-10 (rank : 7)
Query Neighborhood Hits	124	Target Neighborhood Hits	210	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP47_HUMAN
NC score	0.491565 (rank : 9)	θ value	1.99992e-07 (rank : 16)
Query Neighborhood Hits	124	Target Neighborhood Hits	149	Shared Neighborhood Hits	70
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP34_MOUSE
NC score	0.491152 (rank : 10)	θ value	4.30538e-10 (rank : 9)
Query Neighborhood Hits	124	Target Neighborhood Hits	189	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP47_MOUSE
NC score	0.490992 (rank : 11)	θ value	1.53129e-07 (rank : 15)
Query Neighborhood Hits	124	Target Neighborhood Hits	135	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP35_HUMAN
NC score	0.490010 (rank : 12)	θ value	6.87365e-08 (rank : 12)
Query Neighborhood Hits	124	Target Neighborhood Hits	223	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP46_HUMAN
NC score	0.486854 (rank : 13)	θ value	6.87365e-08 (rank : 13)
Query Neighborhood Hits	124	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.486854 (rank : 14)	θ value	6.87365e-08 (rank : 14)
Query Neighborhood Hits	124	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP18_MOUSE
NC score	0.484858 (rank : 15)	θ value	1.69304e-06 (rank : 21)
Query Neighborhood Hits	124	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP40_HUMAN
NC score	0.483725 (rank : 16)	θ value	0.00134147 (rank : 31)
Query Neighborhood Hits	124	Target Neighborhood Hits	81	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP18_HUMAN
NC score	0.483497 (rank : 17)	θ value	4.1701e-05 (rank : 24)
Query Neighborhood Hits	124	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP24_HUMAN
NC score	0.477483 (rank : 18)	θ value	1.87187e-05 (rank : 23)
Query Neighborhood Hits	124	Target Neighborhood Hits	96	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP38_HUMAN
NC score	0.469961 (rank : 19)	θ value	7.59969e-07 (rank : 19)
Query Neighborhood Hits	124	Target Neighborhood Hits	97	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP38_MOUSE
NC score	0.469797 (rank : 20)	θ value	5.81887e-07 (rank : 18)
Query Neighborhood Hits	124	Target Neighborhood Hits	100	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP12_HUMAN
NC score	0.468892 (rank : 21)	θ value	3.77169e-06 (rank : 22)
Query Neighborhood Hits	124	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

USP9X_HUMAN
NC score	0.461587 (rank : 22)	θ value	1.06045e-08 (rank : 10)
Query Neighborhood Hits	124	Target Neighborhood Hits	161	Shared Neighborhood Hits	73
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9Y_HUMAN
NC score	0.457512 (rank : 23)	θ value	1.99992e-07 (rank : 17)
Query Neighborhood Hits	124	Target Neighborhood Hits	109	Shared Neighborhood Hits	72
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

USP9X_MOUSE
NC score	0.449796 (rank : 24)	θ value	9.92553e-07 (rank : 20)
Query Neighborhood Hits	124	Target Neighborhood Hits	171	Shared Neighborhood Hits	73
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP37_HUMAN
NC score	0.420795 (rank : 25)	θ value	1.38499e-08 (rank : 11)
Query Neighborhood Hits	124	Target Neighborhood Hits	208	Shared Neighborhood Hits	78
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP3_MOUSE
NC score	0.411085 (rank : 26)	θ value	9.29e-05 (rank : 25)
Query Neighborhood Hits	124	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP16_HUMAN
NC score	0.408513 (rank : 27)	θ value	0.000270298 (rank : 26)
Query Neighborhood Hits	124	Target Neighborhood Hits	126	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP33_HUMAN
NC score	0.404974 (rank : 28)	θ value	0.000786445 (rank : 29)
Query Neighborhood Hits	124	Target Neighborhood Hits	157	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBPW_MOUSE
NC score	0.404167 (rank : 29)	θ value	0.0193708 (rank : 45)
Query Neighborhood Hits	124	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP36_HUMAN
NC score	0.403748 (rank : 30)	θ value	0.0148317 (rank : 43)
Query Neighborhood Hits	124	Target Neighborhood Hits	232	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP14_HUMAN
NC score	0.395503 (rank : 31)	θ value	0.00298849 (rank : 32)
Query Neighborhood Hits	124	Target Neighborhood Hits	89	Shared Neighborhood Hits	70
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP3_HUMAN
NC score	0.394454 (rank : 32)	θ value	0.000786445 (rank : 30)
Query Neighborhood Hits	124	Target Neighborhood Hits	88	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP30_HUMAN
NC score	0.392736 (rank : 33)	θ value	0.0252991 (rank : 47)
Query Neighborhood Hits	124	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP22_HUMAN
NC score	0.391408 (rank : 34)	θ value	0.00298849 (rank : 33)
Query Neighborhood Hits	124	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
NC score	0.391089 (rank : 35)	θ value	0.00298849 (rank : 34)
Query Neighborhood Hits	124	Target Neighborhood Hits	87	Shared Neighborhood Hits	72
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP2_MOUSE
NC score	0.390700 (rank : 36)	θ value	0.000786445 (rank : 28)
Query Neighborhood Hits	124	Target Neighborhood Hits	86	Shared Neighborhood Hits	72
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP49_HUMAN
NC score	0.387974 (rank : 37)	θ value	0.000602161 (rank : 27)
Query Neighborhood Hits	124	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_MOUSE
NC score	0.385822 (rank : 38)	θ value	0.00390308 (rank : 36)
Query Neighborhood Hits	124	Target Neighborhood Hits	91	Shared Neighborhood Hits	72
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP14_MOUSE
NC score	0.384827 (rank : 39)	θ value	0.00390308 (rank : 35)
Query Neighborhood Hits	124	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP2_HUMAN
NC score	0.380341 (rank : 40)	θ value	0.0148317 (rank : 42)
Query Neighborhood Hits	124	Target Neighborhood Hits	84	Shared Neighborhood Hits	72
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP8_MOUSE
NC score	0.379581 (rank : 41)	θ value	0.00390308 (rank : 37)
Query Neighborhood Hits	124	Target Neighborhood Hits	362	Shared Neighborhood Hits	81
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP20_HUMAN
NC score	0.378515 (rank : 42)	θ value	0.125558 (rank : 57)
Query Neighborhood Hits	124	Target Neighborhood Hits	113	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP51_HUMAN
NC score	0.376659 (rank : 43)	θ value	0.0563607 (rank : 51)
Query Neighborhood Hits	124	Target Neighborhood Hits	162	Shared Neighborhood Hits	72
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UB17L_HUMAN
NC score	0.373663 (rank : 44)	θ value	0.163984 (rank : 59)
Query Neighborhood Hits	124	Target Neighborhood Hits	83	Shared Neighborhood Hits	71
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP50_MOUSE
NC score	0.370801 (rank : 45)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	124	Target Neighborhood Hits	80	Shared Neighborhood Hits	72
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP44_HUMAN
NC score	0.367041 (rank : 46)	θ value	0.0961366 (rank : 56)
Query Neighborhood Hits	124	Target Neighborhood Hits	91	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP21_HUMAN
NC score	0.360211 (rank : 47)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	124	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP21_MOUSE
NC score	0.358713 (rank : 48)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	124	Target Neighborhood Hits	101	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP8_HUMAN
NC score	0.357158 (rank : 49)	θ value	0.0330416 (rank : 48)
Query Neighborhood Hits	124	Target Neighborhood Hits	751	Shared Neighborhood Hits	88
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP42_HUMAN
NC score	0.354691 (rank : 50)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	124	Target Neighborhood Hits	445	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP1_HUMAN
NC score	0.350989 (rank : 51)	θ value	0.21417 (rank : 62)
Query Neighborhood Hits	124	Target Neighborhood Hits	259	Shared Neighborhood Hits	72
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP29_HUMAN
NC score	0.344613 (rank : 52)	θ value	0.00665767 (rank : 40)
Query Neighborhood Hits	124	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP29_MOUSE
NC score	0.340034 (rank : 53)	θ value	0.00509761 (rank : 38)
Query Neighborhood Hits	124	Target Neighborhood Hits	95	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP43_MOUSE
NC score	0.327910 (rank : 54)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	124	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP43_HUMAN
NC score	0.324816 (rank : 55)	θ value	0.0736092 (rank : 54)
Query Neighborhood Hits	124	Target Neighborhood Hits	144	Shared Neighborhood Hits	72
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP26_HUMAN
NC score	0.324344 (rank : 56)	θ value	0.0252991 (rank : 46)
Query Neighborhood Hits	124	Target Neighborhood Hits	108	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP4_MOUSE
NC score	0.318119 (rank : 57)	θ value	0.0563607 (rank : 50)
Query Neighborhood Hits	124	Target Neighborhood Hits	90	Shared Neighborhood Hits	72
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP50_HUMAN
NC score	0.316467 (rank : 58)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	124	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP15_MOUSE
NC score	0.312562 (rank : 59)	θ value	0.163984 (rank : 61)
Query Neighborhood Hits	124	Target Neighborhood Hits	88	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP15_HUMAN
NC score	0.312415 (rank : 60)	θ value	0.163984 (rank : 60)
Query Neighborhood Hits	124	Target Neighborhood Hits	92	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP31_HUMAN
NC score	0.310829 (rank : 61)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	124	Target Neighborhood Hits	293	Shared Neighborhood Hits	72
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP26_MOUSE
NC score	0.308053 (rank : 62)	θ value	0.00869519 (rank : 41)
Query Neighborhood Hits	124	Target Neighborhood Hits	107	Shared Neighborhood Hits	69
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP4_HUMAN
NC score	0.307989 (rank : 63)	θ value	0.47712 (rank : 73)
Query Neighborhood Hits	124	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP13_HUMAN
NC score	0.306401 (rank : 64)	θ value	0.00665767 (rank : 39)
Query Neighborhood Hits	124	Target Neighborhood Hits	99	Shared Neighborhood Hits	71
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP10_MOUSE
NC score	0.297859 (rank : 65)	θ value	0.0736092 (rank : 53)
Query Neighborhood Hits	124	Target Neighborhood Hits	150	Shared Neighborhood Hits	68
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP10_HUMAN
NC score	0.293670 (rank : 66)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	124	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP11_HUMAN
NC score	0.292334 (rank : 67)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	124	Target Neighborhood Hits	88	Shared Neighborhood Hits	72
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP32_HUMAN
NC score	0.276779 (rank : 68)	θ value	0.125558 (rank : 58)
Query Neighborhood Hits	124	Target Neighborhood Hits	170	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP5_MOUSE
NC score	0.275249 (rank : 69)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	124	Target Neighborhood Hits	106	Shared Neighborhood Hits	72
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_HUMAN
NC score	0.271802 (rank : 70)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	124	Target Neighborhood Hits	109	Shared Neighborhood Hits	72
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP6_HUMAN
NC score	0.265719 (rank : 71)	θ value	0.0563607 (rank : 52)
Query Neighborhood Hits	124	Target Neighborhood Hits	188	Shared Neighborhood Hits	74
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

SNUT2_MOUSE
NC score	0.231108 (rank : 72)	θ value	0.813845 (rank : 81)
Query Neighborhood Hits	124	Target Neighborhood Hits	80	Shared Neighborhood Hits	59
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

SNUT2_HUMAN
NC score	0.224873 (rank : 73)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	124	Target Neighborhood Hits	79	Shared Neighborhood Hits	58
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

BRAP_MOUSE
NC score	0.050387 (rank : 74)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	124	Target Neighborhood Hits	409	Shared Neighborhood Hits	32
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CAP2_HUMAN
NC score	0.046267 (rank : 75)	θ value	0.47712 (rank : 70)
Query Neighborhood Hits	124	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P40123, Q6IAY2	Gene names	CAP2
Domain Architecture
Description	Adenylyl cyclase-associated protein 2 (CAP 2).

CAP2_MOUSE
NC score	0.041206 (rank : 76)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	124	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CYT6, Q80YU7, Q9D6L0	Gene names	Cap2
Domain Architecture
Description	Adenylyl cyclase-associated protein 2 (CAP 2).

CUTL1_HUMAN
NC score	0.035892 (rank : 77)	θ value	0.47712 (rank : 72)
Query Neighborhood Hits	124	Target Neighborhood Hits	1574	Shared Neighborhood Hits	34
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CUTL1_MOUSE
NC score	0.035436 (rank : 78)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	124	Target Neighborhood Hits	1620	Shared Neighborhood Hits	36
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CASP_HUMAN
NC score	0.035279 (rank : 79)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	124	Target Neighborhood Hits	1131	Shared Neighborhood Hits	33
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
NC score	0.035265 (rank : 80)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	124	Target Neighborhood Hits	1152	Shared Neighborhood Hits	32
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

NOL6_MOUSE
NC score	0.033845 (rank : 81)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	124	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R5K4, Q6PAN8, Q8C6V4, Q8R5K3, Q8VCG0, Q8WTY7	Gene names	Nol6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

RRMJ3_MOUSE
NC score	0.032980 (rank : 82)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	124	Target Neighborhood Hits	163	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

ATX2_HUMAN
NC score	0.030374 (rank : 83)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	124	Target Neighborhood Hits	375	Shared Neighborhood Hits	4
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX3_MOUSE
NC score	0.026928 (rank : 84)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	124	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CVD2	Gene names	Atxn3, Mjd
Domain Architecture
Description	Ataxin-3 (EC 3.4.22.-) (Machado-Joseph disease protein 1 homolog).

DZIP1_MOUSE
NC score	0.025913 (rank : 85)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	124	Target Neighborhood Hits	530	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

ATX2_MOUSE
NC score	0.025410 (rank : 86)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	124	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

PCNT_HUMAN
NC score	0.024826 (rank : 87)	θ value	1.06291 (rank : 84)
Query Neighborhood Hits	124	Target Neighborhood Hits	1551	Shared Neighborhood Hits	32
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

ATX3_HUMAN
NC score	0.024671 (rank : 88)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	124	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	P54252, O15284, O15285, O15286, Q8N189, Q96TC3, Q96TC4, Q9H3N0	Gene names	ATXN3, ATX3, MJD, MJD1, SCA3
Domain Architecture
Description	Ataxin-3 (EC 3.4.22.-) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein).

KMHN1_MOUSE
NC score	0.023876 (rank : 89)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	124	Target Neighborhood Hits	949	Shared Neighborhood Hits	29
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

CE152_HUMAN
NC score	0.023393 (rank : 90)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	124	Target Neighborhood Hits	976	Shared Neighborhood Hits	28
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

GON4L_MOUSE
NC score	0.023234 (rank : 91)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	124	Target Neighborhood Hits	455	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

TNIP3_HUMAN
NC score	0.020795 (rank : 92)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	124	Target Neighborhood Hits	511	Shared Neighborhood Hits	21
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

MYH10_HUMAN
NC score	0.020607 (rank : 93)	θ value	0.0193708 (rank : 44)
Query Neighborhood Hits	124	Target Neighborhood Hits	1620	Shared Neighborhood Hits	31
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.019459 (rank : 94)	θ value	0.0563607 (rank : 49)
Query Neighborhood Hits	124	Target Neighborhood Hits	1612	Shared Neighborhood Hits	28
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SAS6_HUMAN
NC score	0.019383 (rank : 95)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	124	Target Neighborhood Hits	791	Shared Neighborhood Hits	22
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

CENPF_HUMAN
NC score	0.018838 (rank : 96)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	124	Target Neighborhood Hits	1932	Shared Neighborhood Hits	32
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

SM1L2_MOUSE
NC score	0.018227 (rank : 97)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	124	Target Neighborhood Hits	918	Shared Neighborhood Hits	30
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

KIF5A_HUMAN
NC score	0.016942 (rank : 98)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	124	Target Neighborhood Hits	843	Shared Neighborhood Hits	24
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF5A_MOUSE
NC score	0.016741 (rank : 99)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	124	Target Neighborhood Hits	859	Shared Neighborhood Hits	25
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

RYR1_HUMAN
NC score	0.016627 (rank : 100)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	124	Target Neighborhood Hits	303	Shared Neighborhood Hits	4
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

KINH_MOUSE
NC score	0.016526 (rank : 101)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	124	Target Neighborhood Hits	1082	Shared Neighborhood Hits	30
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

HMMR_MOUSE
NC score	0.016381 (rank : 102)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	124	Target Neighborhood Hits	1178	Shared Neighborhood Hits	26
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

KINH_HUMAN
NC score	0.016172 (rank : 103)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	124	Target Neighborhood Hits	1231	Shared Neighborhood Hits	31
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

IF4G3_HUMAN
NC score	0.015649 (rank : 104)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	124	Target Neighborhood Hits	247	Shared Neighborhood Hits	9
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

AT2B3_HUMAN
NC score	0.013402 (rank : 105)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	124	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q16720, Q12995, Q16858	Gene names	ATP2B3
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 3 (EC 3.6.3.8) (PMCA3) (Plasma membrane calcium pump isoform 3) (Plasma membrane calcium ATPase isoform 3).

OSBP2_MOUSE
NC score	0.013334 (rank : 106)	θ value	1.06291 (rank : 83)
Query Neighborhood Hits	124	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

ITSN1_HUMAN
NC score	0.012746 (rank : 107)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	124	Target Neighborhood Hits	1757	Shared Neighborhood Hits	37
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SNCAP_HUMAN
NC score	0.011405 (rank : 108)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	124	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ROCK1_HUMAN
NC score	0.010484 (rank : 109)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	124	Target Neighborhood Hits	2000	Shared Neighborhood Hits	32
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

ROCK1_MOUSE
NC score	0.009763 (rank : 110)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	124	Target Neighborhood Hits	2126	Shared Neighborhood Hits	33
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

K1C9_HUMAN
NC score	0.009696 (rank : 111)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	124	Target Neighborhood Hits	526	Shared Neighborhood Hits	21
SwissProt Accessions	P35527, O00109, Q14665	Gene names	KRT9
Domain Architecture
Description	Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9).

RHG25_HUMAN
NC score	0.009583 (rank : 112)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	124	Target Neighborhood Hits	550	Shared Neighborhood Hits	26
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PLCB1_HUMAN
NC score	0.009466 (rank : 113)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	124	Target Neighborhood Hits	614	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

PIWL3_HUMAN
NC score	0.009206 (rank : 114)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	124	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z3Z3	Gene names	PIWIL3
Domain Architecture	No domain graphic available
Description	Piwi-like protein 3.

LYST_HUMAN
NC score	0.008306 (rank : 115)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	124	Target Neighborhood Hits	324	Shared Neighborhood Hits	8
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

PTC2_MOUSE
NC score	0.007353 (rank : 116)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	124	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	O35595, Q546T0	Gene names	Ptch2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

ITIH2_MOUSE
NC score	0.006666 (rank : 117)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	124	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q61703	Gene names	Itih2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2).

WEE1B_HUMAN
NC score	0.006169 (rank : 118)	θ value	0.47712 (rank : 74)
Query Neighborhood Hits	124	Target Neighborhood Hits	836	Shared Neighborhood Hits	6
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

HXB4_MOUSE
NC score	0.004826 (rank : 119)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	124	Target Neighborhood Hits	375	Shared Neighborhood Hits	5
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

HXB4_HUMAN
NC score	0.004805 (rank : 120)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	124	Target Neighborhood Hits	376	Shared Neighborhood Hits	5
SwissProt Accessions	P17483, Q9NTA0	Gene names	HOXB4, HOX2F
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6).

GUC2C_HUMAN
NC score	0.003854 (rank : 121)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	124	Target Neighborhood Hits	624	Shared Neighborhood Hits	6
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

RFWD2_MOUSE
NC score	0.003404 (rank : 122)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	124	Target Neighborhood Hits	535	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RFWD2_HUMAN
NC score	0.003337 (rank : 123)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	124	Target Neighborhood Hits	518	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

FARP1_HUMAN
NC score	0.002777 (rank : 124)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	124	Target Neighborhood Hits	241	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

PRDM1_MOUSE
NC score	-0.002274 (rank : 125)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	124	Target Neighborhood Hits	766	Shared Neighborhood Hits	5
SwissProt Accessions	Q60636	Gene names	Prdm1, Blimp1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1).

ZN694_HUMAN
NC score	-0.003758 (rank : 126)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	124	Target Neighborhood Hits	764	Shared Neighborhood Hits	4
SwissProt Accessions	Q63HK3, Q6ZN77	Gene names	ZNF694
Domain Architecture	No domain graphic available
Description	Zinc finger protein 694.