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Network neighborhood for query Sequence : UBP26_HUMAN

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UBP26_HUMAN
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP26_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	108	Target Neighborhood Hits	108	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP29_HUMAN
θ value	0 (rank : 2)	NC score	0.977922 (rank : 2)
Query Neighborhood Hits	108	Target Neighborhood Hits	94	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP37_HUMAN
θ value	1.51281e-164 (rank : 3)	NC score	0.944117 (rank : 5)
Query Neighborhood Hits	108	Target Neighborhood Hits	208	Shared Neighborhood Hits	72
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP26_MOUSE
θ value	5.07123e-136 (rank : 4)	NC score	0.946074 (rank : 4)
Query Neighborhood Hits	108	Target Neighborhood Hits	107	Shared Neighborhood Hits	69
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP29_MOUSE
θ value	7.10925e-122 (rank : 5)	NC score	0.956752 (rank : 3)
Query Neighborhood Hits	108	Target Neighborhood Hits	95	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP50_MOUSE
θ value	1.86753e-13 (rank : 6)	NC score	0.641751 (rank : 6)
Query Neighborhood Hits	108	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP12_HUMAN
θ value	3.52202e-12 (rank : 7)	NC score	0.629685 (rank : 8)
Query Neighborhood Hits	108	Target Neighborhood Hits	85	Shared Neighborhood Hits	69
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP8_MOUSE
θ value	1.33837e-11 (rank : 8)	NC score	0.609451 (rank : 14)
Query Neighborhood Hits	108	Target Neighborhood Hits	362	Shared Neighborhood Hits	72
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP8_HUMAN
θ value	1.74796e-11 (rank : 9)	NC score	0.581419 (rank : 19)
Query Neighborhood Hits	108	Target Neighborhood Hits	751	Shared Neighborhood Hits	76
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP21_HUMAN
θ value	1.133e-10 (rank : 10)	NC score	0.619073 (rank : 11)
Query Neighborhood Hits	108	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP50_HUMAN
θ value	1.47974e-10 (rank : 11)	NC score	0.635468 (rank : 7)
Query Neighborhood Hits	108	Target Neighborhood Hits	75	Shared Neighborhood Hits	64
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP21_MOUSE
θ value	1.9326e-10 (rank : 12)	NC score	0.616830 (rank : 12)
Query Neighborhood Hits	108	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP2_HUMAN
θ value	1.9326e-10 (rank : 13)	NC score	0.608554 (rank : 15)
Query Neighborhood Hits	108	Target Neighborhood Hits	84	Shared Neighborhood Hits	69
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBPW_MOUSE
θ value	2.52405e-10 (rank : 14)	NC score	0.597012 (rank : 18)
Query Neighborhood Hits	108	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP46_HUMAN
θ value	3.29651e-10 (rank : 15)	NC score	0.622699 (rank : 9)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	3.29651e-10 (rank : 16)	NC score	0.622699 (rank : 10)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP6_HUMAN
θ value	3.64472e-09 (rank : 17)	NC score	0.482746 (rank : 44)
Query Neighborhood Hits	108	Target Neighborhood Hits	188	Shared Neighborhood Hits	69
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP32_HUMAN
θ value	4.76016e-09 (rank : 18)	NC score	0.507883 (rank : 38)
Query Neighborhood Hits	108	Target Neighborhood Hits	170	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP2_MOUSE
θ value	6.21693e-09 (rank : 19)	NC score	0.603291 (rank : 16)
Query Neighborhood Hits	108	Target Neighborhood Hits	86	Shared Neighborhood Hits	69
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP42_HUMAN
θ value	6.87365e-08 (rank : 20)	NC score	0.539110 (rank : 27)
Query Neighborhood Hits	108	Target Neighborhood Hits	445	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP3_MOUSE
θ value	8.97725e-08 (rank : 21)	NC score	0.598657 (rank : 17)
Query Neighborhood Hits	108	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP36_HUMAN
θ value	1.17247e-07 (rank : 22)	NC score	0.558647 (rank : 24)
Query Neighborhood Hits	108	Target Neighborhood Hits	232	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP22_MOUSE
θ value	1.53129e-07 (rank : 23)	NC score	0.573881 (rank : 21)
Query Neighborhood Hits	108	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_HUMAN
θ value	1.99992e-07 (rank : 24)	NC score	0.573353 (rank : 22)
Query Neighborhood Hits	108	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP30_HUMAN
θ value	2.61198e-07 (rank : 25)	NC score	0.613931 (rank : 13)
Query Neighborhood Hits	108	Target Neighborhood Hits	94	Shared Neighborhood Hits	68
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP51_HUMAN
θ value	2.61198e-07 (rank : 26)	NC score	0.571110 (rank : 23)
Query Neighborhood Hits	108	Target Neighborhood Hits	162	Shared Neighborhood Hits	69
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP11_HUMAN
θ value	4.45536e-07 (rank : 27)	NC score	0.544561 (rank : 25)
Query Neighborhood Hits	108	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP43_MOUSE
θ value	5.81887e-07 (rank : 28)	NC score	0.540954 (rank : 26)
Query Neighborhood Hits	108	Target Neighborhood Hits	130	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP24_HUMAN
θ value	1.69304e-06 (rank : 29)	NC score	0.501377 (rank : 39)
Query Neighborhood Hits	108	Target Neighborhood Hits	96	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP3_HUMAN
θ value	1.69304e-06 (rank : 30)	NC score	0.579911 (rank : 20)
Query Neighborhood Hits	108	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP15_HUMAN
θ value	3.77169e-06 (rank : 31)	NC score	0.524464 (rank : 30)
Query Neighborhood Hits	108	Target Neighborhood Hits	92	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
θ value	3.77169e-06 (rank : 32)	NC score	0.525778 (rank : 29)
Query Neighborhood Hits	108	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP43_HUMAN
θ value	6.43352e-06 (rank : 33)	NC score	0.518552 (rank : 32)
Query Neighborhood Hits	108	Target Neighborhood Hits	144	Shared Neighborhood Hits	69
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP31_HUMAN
θ value	1.87187e-05 (rank : 34)	NC score	0.488371 (rank : 42)
Query Neighborhood Hits	108	Target Neighborhood Hits	293	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP28_HUMAN
θ value	9.29e-05 (rank : 35)	NC score	0.349612 (rank : 69)
Query Neighborhood Hits	108	Target Neighborhood Hits	117	Shared Neighborhood Hits	69
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP4_HUMAN
θ value	0.000121331 (rank : 36)	NC score	0.516333 (rank : 36)
Query Neighborhood Hits	108	Target Neighborhood Hits	89	Shared Neighborhood Hits	70
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP20_HUMAN
θ value	0.00020696 (rank : 37)	NC score	0.520456 (rank : 31)
Query Neighborhood Hits	108	Target Neighborhood Hits	113	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP13_HUMAN
θ value	0.000270298 (rank : 38)	NC score	0.411249 (rank : 59)
Query Neighborhood Hits	108	Target Neighborhood Hits	99	Shared Neighborhood Hits	68
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP28_MOUSE
θ value	0.000270298 (rank : 39)	NC score	0.360797 (rank : 68)
Query Neighborhood Hits	108	Target Neighborhood Hits	178	Shared Neighborhood Hits	68
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP33_HUMAN
θ value	0.00035302 (rank : 40)	NC score	0.517951 (rank : 33)
Query Neighborhood Hits	108	Target Neighborhood Hits	157	Shared Neighborhood Hits	70
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP44_HUMAN
θ value	0.00035302 (rank : 41)	NC score	0.514461 (rank : 37)
Query Neighborhood Hits	108	Target Neighborhood Hits	91	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP4_MOUSE
θ value	0.00035302 (rank : 42)	NC score	0.516525 (rank : 35)
Query Neighborhood Hits	108	Target Neighborhood Hits	90	Shared Neighborhood Hits	69
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP10_MOUSE
θ value	0.00102713 (rank : 43)	NC score	0.484729 (rank : 43)
Query Neighborhood Hits	108	Target Neighborhood Hits	150	Shared Neighborhood Hits	66
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP10_HUMAN
θ value	0.00134147 (rank : 44)	NC score	0.479555 (rank : 45)
Query Neighborhood Hits	108	Target Neighborhood Hits	153	Shared Neighborhood Hits	67
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP16_HUMAN
θ value	0.00175202 (rank : 45)	NC score	0.537054 (rank : 28)
Query Neighborhood Hits	108	Target Neighborhood Hits	126	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

USP9X_HUMAN
θ value	0.00175202 (rank : 46)	NC score	0.391263 (rank : 62)
Query Neighborhood Hits	108	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

UBP38_MOUSE
θ value	0.00298849 (rank : 47)	NC score	0.452000 (rank : 47)
Query Neighborhood Hits	108	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP35_HUMAN
θ value	0.00390308 (rank : 48)	NC score	0.451081 (rank : 48)
Query Neighborhood Hits	108	Target Neighborhood Hits	223	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP49_HUMAN
θ value	0.00390308 (rank : 49)	NC score	0.493823 (rank : 41)
Query Neighborhood Hits	108	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP14_HUMAN
θ value	0.00509761 (rank : 50)	NC score	0.446832 (rank : 51)
Query Neighborhood Hits	108	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP14_MOUSE
θ value	0.00509761 (rank : 51)	NC score	0.438067 (rank : 54)
Query Neighborhood Hits	108	Target Neighborhood Hits	87	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

USP9X_MOUSE
θ value	0.00665767 (rank : 52)	NC score	0.381735 (rank : 65)
Query Neighborhood Hits	108	Target Neighborhood Hits	171	Shared Neighborhood Hits	72
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP49_MOUSE
θ value	0.00869519 (rank : 53)	NC score	0.497412 (rank : 40)
Query Neighborhood Hits	108	Target Neighborhood Hits	91	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

USP9Y_HUMAN
θ value	0.00869519 (rank : 54)	NC score	0.395026 (rank : 60)
Query Neighborhood Hits	108	Target Neighborhood Hits	109	Shared Neighborhood Hits	70
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP25_MOUSE
θ value	0.0113563 (rank : 55)	NC score	0.326295 (rank : 72)
Query Neighborhood Hits	108	Target Neighborhood Hits	116	Shared Neighborhood Hits	68
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP38_HUMAN
θ value	0.0113563 (rank : 56)	NC score	0.439239 (rank : 53)
Query Neighborhood Hits	108	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UB17L_HUMAN
θ value	0.0148317 (rank : 57)	NC score	0.517349 (rank : 34)
Query Neighborhood Hits	108	Target Neighborhood Hits	83	Shared Neighborhood Hits	69
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP5_HUMAN
θ value	0.0148317 (rank : 58)	NC score	0.387982 (rank : 64)
Query Neighborhood Hits	108	Target Neighborhood Hits	109	Shared Neighborhood Hits	69
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
θ value	0.0148317 (rank : 59)	NC score	0.391275 (rank : 61)
Query Neighborhood Hits	108	Target Neighborhood Hits	106	Shared Neighborhood Hits	69
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP25_HUMAN
θ value	0.0252991 (rank : 60)	NC score	0.324344 (rank : 73)
Query Neighborhood Hits	108	Target Neighborhood Hits	124	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP1_HUMAN
θ value	0.0736092 (rank : 61)	NC score	0.460079 (rank : 46)
Query Neighborhood Hits	108	Target Neighborhood Hits	259	Shared Neighborhood Hits	73
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP34_HUMAN
θ value	0.0736092 (rank : 62)	NC score	0.372112 (rank : 66)
Query Neighborhood Hits	108	Target Neighborhood Hits	210	Shared Neighborhood Hits	67
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP47_MOUSE
θ value	0.0736092 (rank : 63)	NC score	0.437741 (rank : 55)
Query Neighborhood Hits	108	Target Neighborhood Hits	135	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_HUMAN
θ value	0.0961366 (rank : 64)	NC score	0.436038 (rank : 56)
Query Neighborhood Hits	108	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP48_HUMAN
θ value	0.21417 (rank : 65)	NC score	0.448631 (rank : 50)
Query Neighborhood Hits	108	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

BRE1B_HUMAN
θ value	0.279714 (rank : 66)	NC score	0.019170 (rank : 78)
Query Neighborhood Hits	108	Target Neighborhood Hits	1040	Shared Neighborhood Hits	12
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	0.279714 (rank : 67)	NC score	0.020132 (rank : 77)
Query Neighborhood Hits	108	Target Neighborhood Hits	970	Shared Neighborhood Hits	11
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

UBP34_MOUSE
θ value	0.279714 (rank : 68)	NC score	0.369748 (rank : 67)
Query Neighborhood Hits	108	Target Neighborhood Hits	189	Shared Neighborhood Hits	67
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP48_MOUSE
θ value	0.47712 (rank : 69)	NC score	0.445758 (rank : 52)
Query Neighborhood Hits	108	Target Neighborhood Hits	124	Shared Neighborhood Hits	70
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

DMD_HUMAN
θ value	0.62314 (rank : 70)	NC score	0.010901 (rank : 90)
Query Neighborhood Hits	108	Target Neighborhood Hits	1135	Shared Neighborhood Hits	16
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

TFEB_HUMAN
θ value	0.62314 (rank : 71)	NC score	0.022541 (rank : 75)
Query Neighborhood Hits	108	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

RPGF4_MOUSE
θ value	1.06291 (rank : 72)	NC score	0.016583 (rank : 81)
Query Neighborhood Hits	108	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

UBP40_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.415146 (rank : 58)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

CO1A1_HUMAN
θ value	1.81305 (rank : 74)	NC score	0.007925 (rank : 99)
Query Neighborhood Hits	108	Target Neighborhood Hits	475	Shared Neighborhood Hits	4
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

BRD4_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.008515 (rank : 96)
Query Neighborhood Hits	108	Target Neighborhood Hits	851	Shared Neighborhood Hits	13
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

FKBP3_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.014963 (rank : 84)
Query Neighborhood Hits	108	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q62446, Q9WTJ7	Gene names	Fkbp3, Fkbp25
Domain Architecture
Description	FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin- selective 25 kDa immunophilin).

PRP17_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.010148 (rank : 93)
Query Neighborhood Hits	108	Target Neighborhood Hits	297	Shared Neighborhood Hits	3
SwissProt Accessions	O60508, O75471, Q9UPG1	Gene names	CDC40, PRP17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3).

PRP17_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.010170 (rank : 92)
Query Neighborhood Hits	108	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DC48	Gene names	Cdc40, Prp17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (Cell division cycle 40 homolog).

BCDO2_HUMAN
θ value	3.0926 (rank : 79)	NC score	0.012551 (rank : 89)
Query Neighborhood Hits	108	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYV7, Q96JC8, Q96JY5	Gene names	BCDO2
Domain Architecture
Description	Beta,beta-carotene 9',10'-dioxygenase (EC 1.14.99.-) (Beta-carotene dioxygenase 2) (B-diox-II).

CENPE_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.008144 (rank : 98)
Query Neighborhood Hits	108	Target Neighborhood Hits	2060	Shared Neighborhood Hits	24
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GP115_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.008420 (rank : 97)
Query Neighborhood Hits	108	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

AKAP9_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.004639 (rank : 104)
Query Neighborhood Hits	108	Target Neighborhood Hits	1710	Shared Neighborhood Hits	18
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

BNIP3_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.016975 (rank : 80)
Query Neighborhood Hits	108	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q12983, O14620, Q96GP0	Gene names	BNIP3, NIP3
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.

BRCA2_MOUSE
θ value	4.03905 (rank : 84)	NC score	0.013966 (rank : 88)
Query Neighborhood Hits	108	Target Neighborhood Hits	222	Shared Neighborhood Hits	6
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

CO1A1_MOUSE
θ value	4.03905 (rank : 85)	NC score	0.007058 (rank : 100)
Query Neighborhood Hits	108	Target Neighborhood Hits	457	Shared Neighborhood Hits	4
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

NSF1C_MOUSE
θ value	4.03905 (rank : 86)	NC score	0.015610 (rank : 83)
Query Neighborhood Hits	108	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

PER2_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.014294 (rank : 86)
Query Neighborhood Hits	108	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

SPESP_MOUSE
θ value	4.03905 (rank : 88)	NC score	0.020755 (rank : 76)
Query Neighborhood Hits	108	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D5A0, Q9D5X8	Gene names	Spesp1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor.

AKAP6_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.015722 (rank : 82)
Query Neighborhood Hits	108	Target Neighborhood Hits	263	Shared Neighborhood Hits	10
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

CABYR_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.014741 (rank : 85)
Query Neighborhood Hits	108	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

AHTF1_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.014168 (rank : 87)
Query Neighborhood Hits	108	Target Neighborhood Hits	286	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CE005_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.005600 (rank : 102)
Query Neighborhood Hits	108	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CLSPN_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.017260 (rank : 79)
Query Neighborhood Hits	108	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

MK07_HUMAN
θ value	6.88961 (rank : 94)	NC score	-0.004379 (rank : 113)
Query Neighborhood Hits	108	Target Neighborhood Hits	1087	Shared Neighborhood Hits	5
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MRCKB_MOUSE
θ value	6.88961 (rank : 95)	NC score	-0.003130 (rank : 111)
Query Neighborhood Hits	108	Target Neighborhood Hits	2180	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NOLC1_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.008769 (rank : 95)
Query Neighborhood Hits	108	Target Neighborhood Hits	452	Shared Neighborhood Hits	5
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

TRIPB_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.008831 (rank : 94)
Query Neighborhood Hits	108	Target Neighborhood Hits	1587	Shared Neighborhood Hits	18
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

UBP7_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.388437 (rank : 63)
Query Neighborhood Hits	108	Target Neighborhood Hits	93	Shared Neighborhood Hits	68
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

ABCA2_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.001981 (rank : 107)
Query Neighborhood Hits	108	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

CD1D_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.001491 (rank : 108)
Query Neighborhood Hits	108	Target Neighborhood Hits	198	Shared Neighborhood Hits	2
SwissProt Accessions	P15813, Q9UMM3, Q9Y5M4	Gene names	CD1D
Domain Architecture
Description	T-cell surface glycoprotein CD1d precursor (CD1d antigen) (R3G1).

CENPK_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.010591 (rank : 91)
Query Neighborhood Hits	108	Target Neighborhood Hits	149	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

CK5P2_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.005233 (rank : 103)
Query Neighborhood Hits	108	Target Neighborhood Hits	1433	Shared Neighborhood Hits	17
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

MYO15_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.000845 (rank : 110)
Query Neighborhood Hits	108	Target Neighborhood Hits	467	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PHF8_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.004306 (rank : 105)
Query Neighborhood Hits	108	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

REST_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.002409 (rank : 106)
Query Neighborhood Hits	108	Target Neighborhood Hits	1605	Shared Neighborhood Hits	18
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

STYK1_MOUSE
θ value	8.99809 (rank : 106)	NC score	-0.003204 (rank : 112)
Query Neighborhood Hits	108	Target Neighborhood Hits	779	Shared Neighborhood Hits	4
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

TLR1_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.001471 (rank : 109)
Query Neighborhood Hits	108	Target Neighborhood Hits	280	Shared Neighborhood Hits	2
SwissProt Accessions	Q15399, O15452, Q9UG90	Gene names	TLR1, KIAA0012
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

TM108_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.006637 (rank : 101)
Query Neighborhood Hits	108	Target Neighborhood Hits	336	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

BRAP_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.055766 (rank : 74)
Query Neighborhood Hits	108	Target Neighborhood Hits	409	Shared Neighborhood Hits	22
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

SNUT2_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.333387 (rank : 71)
Query Neighborhood Hits	108	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

SNUT2_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.346726 (rank : 70)
Query Neighborhood Hits	108	Target Neighborhood Hits	80	Shared Neighborhood Hits	56
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBP18_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.450962 (rank : 49)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP18_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.428623 (rank : 57)
Query Neighborhood Hits	108	Target Neighborhood Hits	77	Shared Neighborhood Hits	65
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

Hits sorted by NC score

UBP26_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	108	Target Neighborhood Hits	108	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP29_HUMAN
NC score	0.977922 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	108	Target Neighborhood Hits	94	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP29_MOUSE
NC score	0.956752 (rank : 3)	θ value	7.10925e-122 (rank : 5)
Query Neighborhood Hits	108	Target Neighborhood Hits	95	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP26_MOUSE
NC score	0.946074 (rank : 4)	θ value	5.07123e-136 (rank : 4)
Query Neighborhood Hits	108	Target Neighborhood Hits	107	Shared Neighborhood Hits	69
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP37_HUMAN
NC score	0.944117 (rank : 5)	θ value	1.51281e-164 (rank : 3)
Query Neighborhood Hits	108	Target Neighborhood Hits	208	Shared Neighborhood Hits	72
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP50_MOUSE
NC score	0.641751 (rank : 6)	θ value	1.86753e-13 (rank : 6)
Query Neighborhood Hits	108	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP50_HUMAN
NC score	0.635468 (rank : 7)	θ value	1.47974e-10 (rank : 11)
Query Neighborhood Hits	108	Target Neighborhood Hits	75	Shared Neighborhood Hits	64
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP12_HUMAN
NC score	0.629685 (rank : 8)	θ value	3.52202e-12 (rank : 7)
Query Neighborhood Hits	108	Target Neighborhood Hits	85	Shared Neighborhood Hits	69
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP46_HUMAN
NC score	0.622699 (rank : 9)	θ value	3.29651e-10 (rank : 15)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.622699 (rank : 10)	θ value	3.29651e-10 (rank : 16)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP21_HUMAN
NC score	0.619073 (rank : 11)	θ value	1.133e-10 (rank : 10)
Query Neighborhood Hits	108	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP21_MOUSE
NC score	0.616830 (rank : 12)	θ value	1.9326e-10 (rank : 12)
Query Neighborhood Hits	108	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP30_HUMAN
NC score	0.613931 (rank : 13)	θ value	2.61198e-07 (rank : 25)
Query Neighborhood Hits	108	Target Neighborhood Hits	94	Shared Neighborhood Hits	68
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP8_MOUSE
NC score	0.609451 (rank : 14)	θ value	1.33837e-11 (rank : 8)
Query Neighborhood Hits	108	Target Neighborhood Hits	362	Shared Neighborhood Hits	72
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP2_HUMAN
NC score	0.608554 (rank : 15)	θ value	1.9326e-10 (rank : 13)
Query Neighborhood Hits	108	Target Neighborhood Hits	84	Shared Neighborhood Hits	69
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_MOUSE
NC score	0.603291 (rank : 16)	θ value	6.21693e-09 (rank : 19)
Query Neighborhood Hits	108	Target Neighborhood Hits	86	Shared Neighborhood Hits	69
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP3_MOUSE
NC score	0.598657 (rank : 17)	θ value	8.97725e-08 (rank : 21)
Query Neighborhood Hits	108	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBPW_MOUSE
NC score	0.597012 (rank : 18)	θ value	2.52405e-10 (rank : 14)
Query Neighborhood Hits	108	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP8_HUMAN
NC score	0.581419 (rank : 19)	θ value	1.74796e-11 (rank : 9)
Query Neighborhood Hits	108	Target Neighborhood Hits	751	Shared Neighborhood Hits	76
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP3_HUMAN
NC score	0.579911 (rank : 20)	θ value	1.69304e-06 (rank : 30)
Query Neighborhood Hits	108	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP22_MOUSE
NC score	0.573881 (rank : 21)	θ value	1.53129e-07 (rank : 23)
Query Neighborhood Hits	108	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_HUMAN
NC score	0.573353 (rank : 22)	θ value	1.99992e-07 (rank : 24)
Query Neighborhood Hits	108	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
NC score	0.571110 (rank : 23)	θ value	2.61198e-07 (rank : 26)
Query Neighborhood Hits	108	Target Neighborhood Hits	162	Shared Neighborhood Hits	69
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP36_HUMAN
NC score	0.558647 (rank : 24)	θ value	1.17247e-07 (rank : 22)
Query Neighborhood Hits	108	Target Neighborhood Hits	232	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP11_HUMAN
NC score	0.544561 (rank : 25)	θ value	4.45536e-07 (rank : 27)
Query Neighborhood Hits	108	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP43_MOUSE
NC score	0.540954 (rank : 26)	θ value	5.81887e-07 (rank : 28)
Query Neighborhood Hits	108	Target Neighborhood Hits	130	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP42_HUMAN
NC score	0.539110 (rank : 27)	θ value	6.87365e-08 (rank : 20)
Query Neighborhood Hits	108	Target Neighborhood Hits	445	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP16_HUMAN
NC score	0.537054 (rank : 28)	θ value	0.00175202 (rank : 45)
Query Neighborhood Hits	108	Target Neighborhood Hits	126	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP15_MOUSE
NC score	0.525778 (rank : 29)	θ value	3.77169e-06 (rank : 32)
Query Neighborhood Hits	108	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP15_HUMAN
NC score	0.524464 (rank : 30)	θ value	3.77169e-06 (rank : 31)
Query Neighborhood Hits	108	Target Neighborhood Hits	92	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP20_HUMAN
NC score	0.520456 (rank : 31)	θ value	0.00020696 (rank : 37)
Query Neighborhood Hits	108	Target Neighborhood Hits	113	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP43_HUMAN
NC score	0.518552 (rank : 32)	θ value	6.43352e-06 (rank : 33)
Query Neighborhood Hits	108	Target Neighborhood Hits	144	Shared Neighborhood Hits	69
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP33_HUMAN
NC score	0.517951 (rank : 33)	θ value	0.00035302 (rank : 40)
Query Neighborhood Hits	108	Target Neighborhood Hits	157	Shared Neighborhood Hits	70
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UB17L_HUMAN
NC score	0.517349 (rank : 34)	θ value	0.0148317 (rank : 57)
Query Neighborhood Hits	108	Target Neighborhood Hits	83	Shared Neighborhood Hits	69
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP4_MOUSE
NC score	0.516525 (rank : 35)	θ value	0.00035302 (rank : 42)
Query Neighborhood Hits	108	Target Neighborhood Hits	90	Shared Neighborhood Hits	69
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP4_HUMAN
NC score	0.516333 (rank : 36)	θ value	0.000121331 (rank : 36)
Query Neighborhood Hits	108	Target Neighborhood Hits	89	Shared Neighborhood Hits	70
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP44_HUMAN
NC score	0.514461 (rank : 37)	θ value	0.00035302 (rank : 41)
Query Neighborhood Hits	108	Target Neighborhood Hits	91	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP32_HUMAN
NC score	0.507883 (rank : 38)	θ value	4.76016e-09 (rank : 18)
Query Neighborhood Hits	108	Target Neighborhood Hits	170	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP24_HUMAN
NC score	0.501377 (rank : 39)	θ value	1.69304e-06 (rank : 29)
Query Neighborhood Hits	108	Target Neighborhood Hits	96	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP49_MOUSE
NC score	0.497412 (rank : 40)	θ value	0.00869519 (rank : 53)
Query Neighborhood Hits	108	Target Neighborhood Hits	91	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_HUMAN
NC score	0.493823 (rank : 41)	θ value	0.00390308 (rank : 49)
Query Neighborhood Hits	108	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP31_HUMAN
NC score	0.488371 (rank : 42)	θ value	1.87187e-05 (rank : 34)
Query Neighborhood Hits	108	Target Neighborhood Hits	293	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP10_MOUSE
NC score	0.484729 (rank : 43)	θ value	0.00102713 (rank : 43)
Query Neighborhood Hits	108	Target Neighborhood Hits	150	Shared Neighborhood Hits	66
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP6_HUMAN
NC score	0.482746 (rank : 44)	θ value	3.64472e-09 (rank : 17)
Query Neighborhood Hits	108	Target Neighborhood Hits	188	Shared Neighborhood Hits	69
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP10_HUMAN
NC score	0.479555 (rank : 45)	θ value	0.00134147 (rank : 44)
Query Neighborhood Hits	108	Target Neighborhood Hits	153	Shared Neighborhood Hits	67
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP1_HUMAN
NC score	0.460079 (rank : 46)	θ value	0.0736092 (rank : 61)
Query Neighborhood Hits	108	Target Neighborhood Hits	259	Shared Neighborhood Hits	73
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP38_MOUSE
NC score	0.452000 (rank : 47)	θ value	0.00298849 (rank : 47)
Query Neighborhood Hits	108	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP35_HUMAN
NC score	0.451081 (rank : 48)	θ value	0.00390308 (rank : 48)
Query Neighborhood Hits	108	Target Neighborhood Hits	223	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP18_HUMAN
NC score	0.450962 (rank : 49)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP48_HUMAN
NC score	0.448631 (rank : 50)	θ value	0.21417 (rank : 65)
Query Neighborhood Hits	108	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP14_HUMAN
NC score	0.446832 (rank : 51)	θ value	0.00509761 (rank : 50)
Query Neighborhood Hits	108	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP48_MOUSE
NC score	0.445758 (rank : 52)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	108	Target Neighborhood Hits	124	Shared Neighborhood Hits	70
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP38_HUMAN
NC score	0.439239 (rank : 53)	θ value	0.0113563 (rank : 56)
Query Neighborhood Hits	108	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP14_MOUSE
NC score	0.438067 (rank : 54)	θ value	0.00509761 (rank : 51)
Query Neighborhood Hits	108	Target Neighborhood Hits	87	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP47_MOUSE
NC score	0.437741 (rank : 55)	θ value	0.0736092 (rank : 63)
Query Neighborhood Hits	108	Target Neighborhood Hits	135	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_HUMAN
NC score	0.436038 (rank : 56)	θ value	0.0961366 (rank : 64)
Query Neighborhood Hits	108	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP18_MOUSE
NC score	0.428623 (rank : 57)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	108	Target Neighborhood Hits	77	Shared Neighborhood Hits	65
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP40_HUMAN
NC score	0.415146 (rank : 58)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	108	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP13_HUMAN
NC score	0.411249 (rank : 59)	θ value	0.000270298 (rank : 38)
Query Neighborhood Hits	108	Target Neighborhood Hits	99	Shared Neighborhood Hits	68
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

USP9Y_HUMAN
NC score	0.395026 (rank : 60)	θ value	0.00869519 (rank : 54)
Query Neighborhood Hits	108	Target Neighborhood Hits	109	Shared Neighborhood Hits	70
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP5_MOUSE
NC score	0.391275 (rank : 61)	θ value	0.0148317 (rank : 59)
Query Neighborhood Hits	108	Target Neighborhood Hits	106	Shared Neighborhood Hits	69
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

USP9X_HUMAN
NC score	0.391263 (rank : 62)	θ value	0.00175202 (rank : 46)
Query Neighborhood Hits	108	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

UBP7_HUMAN
NC score	0.388437 (rank : 63)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	108	Target Neighborhood Hits	93	Shared Neighborhood Hits	68
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP5_HUMAN
NC score	0.387982 (rank : 64)	θ value	0.0148317 (rank : 58)
Query Neighborhood Hits	108	Target Neighborhood Hits	109	Shared Neighborhood Hits	69
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

USP9X_MOUSE
NC score	0.381735 (rank : 65)	θ value	0.00665767 (rank : 52)
Query Neighborhood Hits	108	Target Neighborhood Hits	171	Shared Neighborhood Hits	72
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP34_HUMAN
NC score	0.372112 (rank : 66)	θ value	0.0736092 (rank : 62)
Query Neighborhood Hits	108	Target Neighborhood Hits	210	Shared Neighborhood Hits	67
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
NC score	0.369748 (rank : 67)	θ value	0.279714 (rank : 68)
Query Neighborhood Hits	108	Target Neighborhood Hits	189	Shared Neighborhood Hits	67
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP28_MOUSE
NC score	0.360797 (rank : 68)	θ value	0.000270298 (rank : 39)
Query Neighborhood Hits	108	Target Neighborhood Hits	178	Shared Neighborhood Hits	68
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_HUMAN
NC score	0.349612 (rank : 69)	θ value	9.29e-05 (rank : 35)
Query Neighborhood Hits	108	Target Neighborhood Hits	117	Shared Neighborhood Hits	69
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

SNUT2_MOUSE
NC score	0.346726 (rank : 70)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	108	Target Neighborhood Hits	80	Shared Neighborhood Hits	56
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

SNUT2_HUMAN
NC score	0.333387 (rank : 71)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	108	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP25_MOUSE
NC score	0.326295 (rank : 72)	θ value	0.0113563 (rank : 55)
Query Neighborhood Hits	108	Target Neighborhood Hits	116	Shared Neighborhood Hits	68
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP25_HUMAN
NC score	0.324344 (rank : 73)	θ value	0.0252991 (rank : 60)
Query Neighborhood Hits	108	Target Neighborhood Hits	124	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

BRAP_MOUSE
NC score	0.055766 (rank : 74)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	108	Target Neighborhood Hits	409	Shared Neighborhood Hits	22
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

TFEB_HUMAN
NC score	0.022541 (rank : 75)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	108	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

SPESP_MOUSE
NC score	0.020755 (rank : 76)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	108	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D5A0, Q9D5X8	Gene names	Spesp1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor.

BRE1B_MOUSE
NC score	0.020132 (rank : 77)	θ value	0.279714 (rank : 67)
Query Neighborhood Hits	108	Target Neighborhood Hits	970	Shared Neighborhood Hits	11
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
NC score	0.019170 (rank : 78)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	108	Target Neighborhood Hits	1040	Shared Neighborhood Hits	12
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

CLSPN_MOUSE
NC score	0.017260 (rank : 79)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	108	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

BNIP3_HUMAN
NC score	0.016975 (rank : 80)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	108	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q12983, O14620, Q96GP0	Gene names	BNIP3, NIP3
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.

RPGF4_MOUSE
NC score	0.016583 (rank : 81)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	108	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

AKAP6_HUMAN
NC score	0.015722 (rank : 82)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	108	Target Neighborhood Hits	263	Shared Neighborhood Hits	10
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

NSF1C_MOUSE
NC score	0.015610 (rank : 83)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	108	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

FKBP3_MOUSE
NC score	0.014963 (rank : 84)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	108	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q62446, Q9WTJ7	Gene names	Fkbp3, Fkbp25
Domain Architecture
Description	FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin- selective 25 kDa immunophilin).

CABYR_HUMAN
NC score	0.014741 (rank : 85)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	108	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

PER2_HUMAN
NC score	0.014294 (rank : 86)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	108	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

AHTF1_HUMAN
NC score	0.014168 (rank : 87)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	108	Target Neighborhood Hits	286	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

BRCA2_MOUSE
NC score	0.013966 (rank : 88)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	108	Target Neighborhood Hits	222	Shared Neighborhood Hits	6
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

BCDO2_HUMAN
NC score	0.012551 (rank : 89)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	108	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYV7, Q96JC8, Q96JY5	Gene names	BCDO2
Domain Architecture
Description	Beta,beta-carotene 9',10'-dioxygenase (EC 1.14.99.-) (Beta-carotene dioxygenase 2) (B-diox-II).

DMD_HUMAN
NC score	0.010901 (rank : 90)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	108	Target Neighborhood Hits	1135	Shared Neighborhood Hits	16
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

CENPK_MOUSE
NC score	0.010591 (rank : 91)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	108	Target Neighborhood Hits	149	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ESN5, Q3UXA9, Q569Q3, Q8C469	Gene names	Cenpk, Solt
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (SoxLZ/Sox6 leucine zipper-binding protein in testis).

PRP17_MOUSE
NC score	0.010170 (rank : 92)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	108	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DC48	Gene names	Cdc40, Prp17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (Cell division cycle 40 homolog).

PRP17_HUMAN
NC score	0.010148 (rank : 93)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	108	Target Neighborhood Hits	297	Shared Neighborhood Hits	3
SwissProt Accessions	O60508, O75471, Q9UPG1	Gene names	CDC40, PRP17
Domain Architecture
Description	Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division cycle 40 homolog) (EH-binding protein 3) (Ehb3).

TRIPB_HUMAN
NC score	0.008831 (rank : 94)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	108	Target Neighborhood Hits	1587	Shared Neighborhood Hits	18
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

NOLC1_HUMAN
NC score	0.008769 (rank : 95)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	108	Target Neighborhood Hits	452	Shared Neighborhood Hits	5
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

BRD4_HUMAN
NC score	0.008515 (rank : 96)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	108	Target Neighborhood Hits	851	Shared Neighborhood Hits	13
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

GP115_HUMAN
NC score	0.008420 (rank : 97)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	108	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

CENPE_HUMAN
NC score	0.008144 (rank : 98)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	108	Target Neighborhood Hits	2060	Shared Neighborhood Hits	24
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CO1A1_HUMAN
NC score	0.007925 (rank : 99)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	108	Target Neighborhood Hits	475	Shared Neighborhood Hits	4
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO1A1_MOUSE
NC score	0.007058 (rank : 100)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	108	Target Neighborhood Hits	457	Shared Neighborhood Hits	4
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

TM108_MOUSE
NC score	0.006637 (rank : 101)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	108	Target Neighborhood Hits	336	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

CE005_HUMAN
NC score	0.005600 (rank : 102)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	108	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CK5P2_HUMAN
NC score	0.005233 (rank : 103)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	108	Target Neighborhood Hits	1433	Shared Neighborhood Hits	17
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

AKAP9_HUMAN
NC score	0.004639 (rank : 104)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	108	Target Neighborhood Hits	1710	Shared Neighborhood Hits	18
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

PHF8_HUMAN
NC score	0.004306 (rank : 105)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	108	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

REST_HUMAN
NC score	0.002409 (rank : 106)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	108	Target Neighborhood Hits	1605	Shared Neighborhood Hits	18
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ABCA2_HUMAN
NC score	0.001981 (rank : 107)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	108	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

CD1D_HUMAN
NC score	0.001491 (rank : 108)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	108	Target Neighborhood Hits	198	Shared Neighborhood Hits	2
SwissProt Accessions	P15813, Q9UMM3, Q9Y5M4	Gene names	CD1D
Domain Architecture
Description	T-cell surface glycoprotein CD1d precursor (CD1d antigen) (R3G1).

TLR1_HUMAN
NC score	0.001471 (rank : 109)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	108	Target Neighborhood Hits	280	Shared Neighborhood Hits	2
SwissProt Accessions	Q15399, O15452, Q9UG90	Gene names	TLR1, KIAA0012
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

MYO15_MOUSE
NC score	0.000845 (rank : 110)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	108	Target Neighborhood Hits	467	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MRCKB_MOUSE
NC score	-0.003130 (rank : 111)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	108	Target Neighborhood Hits	2180	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

STYK1_MOUSE
NC score	-0.003204 (rank : 112)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	108	Target Neighborhood Hits	779	Shared Neighborhood Hits	4
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

MK07_HUMAN
NC score	-0.004379 (rank : 113)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	108	Target Neighborhood Hits	1087	Shared Neighborhood Hits	5
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).