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Network neighborhood for query Sequence : USP9Y_HUMAN

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USP9Y_HUMAN
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP24_HUMAN
θ value	0 (rank : 1)	NC score	0.941066 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	96	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

USP9X_HUMAN
θ value	0 (rank : 2)	NC score	0.995257 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	161	Shared Neighborhood Hits	88
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
θ value	0 (rank : 3)	NC score	0.994715 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	171	Shared Neighborhood Hits	89
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9Y_HUMAN
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP34_HUMAN
θ value	2.4834e-66 (rank : 5)	NC score	0.813321 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	210	Shared Neighborhood Hits	72
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
θ value	6.11685e-65 (rank : 6)	NC score	0.813590 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	189	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP48_HUMAN
θ value	5.584e-34 (rank : 7)	NC score	0.783156 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
θ value	4.72714e-33 (rank : 8)	NC score	0.779538 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP47_MOUSE
θ value	1.79631e-32 (rank : 9)	NC score	0.765869 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	135	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_HUMAN
θ value	3.3877e-31 (rank : 10)	NC score	0.763105 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP7_HUMAN
θ value	5.59698e-26 (rank : 11)	NC score	0.788483 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	93	Shared Neighborhood Hits	71
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP40_HUMAN
θ value	1.62847e-25 (rank : 12)	NC score	0.782016 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP46_HUMAN
θ value	5.60996e-18 (rank : 13)	NC score	0.723573 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	81	Shared Neighborhood Hits	74
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	5.60996e-18 (rank : 14)	NC score	0.723573 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	81	Shared Neighborhood Hits	74
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP8_HUMAN
θ value	9.56915e-18 (rank : 15)	NC score	0.618054 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	751	Shared Neighborhood Hits	80
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP36_HUMAN
θ value	1.63225e-17 (rank : 16)	NC score	0.697959 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	232	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP8_MOUSE
θ value	2.13179e-17 (rank : 17)	NC score	0.650594 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	362	Shared Neighborhood Hits	76
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP12_HUMAN
θ value	6.20254e-17 (rank : 18)	NC score	0.721870 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UB17L_HUMAN
θ value	1.80466e-16 (rank : 19)	NC score	0.701529 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP22_HUMAN
θ value	4.02038e-16 (rank : 20)	NC score	0.675370 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
θ value	6.85773e-16 (rank : 21)	NC score	0.673698 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP42_HUMAN
θ value	3.40345e-15 (rank : 22)	NC score	0.660990 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	445	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP51_HUMAN
θ value	4.44505e-15 (rank : 23)	NC score	0.666919 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	162	Shared Neighborhood Hits	73
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP3_MOUSE
θ value	3.76295e-14 (rank : 24)	NC score	0.660095 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBPW_MOUSE
θ value	4.91457e-14 (rank : 25)	NC score	0.698344 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP3_HUMAN
θ value	3.18553e-13 (rank : 26)	NC score	0.657820 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP33_HUMAN
θ value	1.2105e-12 (rank : 27)	NC score	0.644711 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	157	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP20_HUMAN
θ value	2.0648e-12 (rank : 28)	NC score	0.652127 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP49_HUMAN
θ value	2.0648e-12 (rank : 29)	NC score	0.629940 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP18_HUMAN
θ value	4.59992e-12 (rank : 30)	NC score	0.713180 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP49_MOUSE
θ value	1.02475e-11 (rank : 31)	NC score	0.626783 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP50_MOUSE
θ value	3.89403e-11 (rank : 32)	NC score	0.650230 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP2_MOUSE
θ value	1.133e-10 (rank : 33)	NC score	0.630600 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP38_HUMAN
θ value	1.133e-10 (rank : 34)	NC score	0.578156 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP2_HUMAN
θ value	1.47974e-10 (rank : 35)	NC score	0.633968 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	84	Shared Neighborhood Hits	73
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP38_MOUSE
θ value	4.30538e-10 (rank : 36)	NC score	0.565477 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP15_HUMAN
θ value	5.62301e-10 (rank : 37)	NC score	0.554063 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP44_HUMAN
θ value	5.62301e-10 (rank : 38)	NC score	0.627996 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP15_MOUSE
θ value	7.34386e-10 (rank : 39)	NC score	0.553998 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP18_MOUSE
θ value	2.13673e-09 (rank : 40)	NC score	0.677330 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP28_MOUSE
θ value	3.64472e-09 (rank : 41)	NC score	0.480352 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	178	Shared Neighborhood Hits	74
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP50_HUMAN
θ value	1.38499e-08 (rank : 42)	NC score	0.627091 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP28_HUMAN
θ value	2.36244e-08 (rank : 43)	NC score	0.479011 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	117	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP11_HUMAN
θ value	1.17247e-07 (rank : 44)	NC score	0.550788 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP21_HUMAN
θ value	1.99992e-07 (rank : 45)	NC score	0.610923 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP21_MOUSE
θ value	1.99992e-07 (rank : 46)	NC score	0.612577 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP25_HUMAN
θ value	1.99992e-07 (rank : 47)	NC score	0.457512 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP25_MOUSE
θ value	2.61198e-07 (rank : 48)	NC score	0.458991 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	116	Shared Neighborhood Hits	72
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP31_HUMAN
θ value	2.61198e-07 (rank : 49)	NC score	0.546470 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	293	Shared Neighborhood Hits	75
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP4_HUMAN
θ value	4.45536e-07 (rank : 50)	NC score	0.531099 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP10_HUMAN
θ value	5.81887e-07 (rank : 51)	NC score	0.534135 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP37_HUMAN
θ value	9.92553e-07 (rank : 52)	NC score	0.500148 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	208	Shared Neighborhood Hits	73
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP10_MOUSE
θ value	1.69304e-06 (rank : 53)	NC score	0.530778 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	150	Shared Neighborhood Hits	69
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP4_MOUSE
θ value	1.69304e-06 (rank : 54)	NC score	0.530146 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP43_MOUSE
θ value	2.21117e-06 (rank : 55)	NC score	0.538758 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	130	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP16_HUMAN
θ value	3.77169e-06 (rank : 56)	NC score	0.591604 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP14_HUMAN
θ value	4.92598e-06 (rank : 57)	NC score	0.548923 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP43_HUMAN
θ value	1.09739e-05 (rank : 58)	NC score	0.533682 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	144	Shared Neighborhood Hits	73
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP14_MOUSE
θ value	0.000158464 (rank : 59)	NC score	0.512750 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

SNUT2_HUMAN
θ value	0.00020696 (rank : 60)	NC score	0.447961 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	79	Shared Neighborhood Hits	59
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

SNUT2_MOUSE
θ value	0.00020696 (rank : 61)	NC score	0.458300 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBP5_MOUSE
θ value	0.00020696 (rank : 62)	NC score	0.405072 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP35_HUMAN
θ value	0.000270298 (rank : 63)	NC score	0.566184 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	223	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP29_HUMAN
θ value	0.000602161 (rank : 64)	NC score	0.424684 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP5_HUMAN
θ value	0.000786445 (rank : 65)	NC score	0.402605 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	73
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP13_HUMAN
θ value	0.00390308 (rank : 66)	NC score	0.382969 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	99	Shared Neighborhood Hits	72
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP1_HUMAN
θ value	0.00509761 (rank : 67)	NC score	0.546822 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	259	Shared Neighborhood Hits	74
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP26_MOUSE
θ value	0.00509761 (rank : 68)	NC score	0.347276 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	107	Shared Neighborhood Hits	70
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP26_HUMAN
θ value	0.00869519 (rank : 69)	NC score	0.395026 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	108	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP29_MOUSE
θ value	0.0193708 (rank : 70)	NC score	0.392946 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP6_HUMAN
θ value	0.0252991 (rank : 71)	NC score	0.394639 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	188	Shared Neighborhood Hits	75
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP32_HUMAN
θ value	0.0330416 (rank : 72)	NC score	0.423843 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	170	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

BIRC6_HUMAN
θ value	0.0961366 (rank : 73)	NC score	0.039410 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

DMD_MOUSE
θ value	0.62314 (rank : 74)	NC score	0.018024 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	1111	Shared Neighborhood Hits	16
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

CF211_HUMAN
θ value	1.06291 (rank : 75)	NC score	0.039200 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H993, Q96FC6, Q9UFY5	Gene names	C6orf211
Domain Architecture	No domain graphic available
Description	UPF0364 protein C6orf211.

SYNE1_HUMAN
θ value	1.06291 (rank : 76)	NC score	0.013431 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	1484	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

PRPC_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.087679 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

SMC2_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.015187 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	1131	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

PPE1_HUMAN
θ value	1.81305 (rank : 79)	NC score	0.008725 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	137	Shared Neighborhood Hits	2
SwissProt Accessions	O14829, O15253, Q9NU21, Q9UJH0	Gene names	PPEF1, PPEF, PPP7C
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 1 (EC 3.1.3.16) (PPEF-1) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7).

ZN516_HUMAN
θ value	1.81305 (rank : 80)	NC score	-0.001075 (rank : 110)
Query Neighborhood Hits	109	Target Neighborhood Hits	854	Shared Neighborhood Hits	7
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

CI126_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.037518 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N9R8, Q5T163, Q8N1I4	Gene names	C9orf126
Domain Architecture	No domain graphic available
Description	Protein C9orf126.

CI126_MOUSE
θ value	2.36792 (rank : 82)	NC score	0.037502 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C8N2, Q8C409, Q8C8K2	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf126 homolog.

ATBF1_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.001298 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	1547	Shared Neighborhood Hits	9
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

SMC2_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.005205 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	1405	Shared Neighborhood Hits	17
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SP6_MOUSE
θ value	4.03905 (rank : 85)	NC score	0.000208 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	704	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ESX2, Q6VM22	Gene names	Sp6, Epfn, Klf14
Domain Architecture	No domain graphic available
Description	Transcription factor Sp6 (Krueppel-like factor 14) (Epiprofin).

BRPF3_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.003628 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	217	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

PAR10_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.014213 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

PRP1_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.057199 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	385	Shared Neighborhood Hits	9
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PYGO1_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.010458 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

STON2_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.007207 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

VPS52_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.013173 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N1B4, Q53GR4, Q5JPA0, Q5SQW1, Q8IUN6, Q9NPT5	Gene names	VPS52, SACM2L
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 52 (SAC2 suppressor of actin mutations 2-like protein).

CHRC1_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.062447 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRG0	Gene names	CHRAC1, CHRAC15
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15).

KIF1C_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.002612 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	171	Shared Neighborhood Hits	5
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

LIX1_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.027639 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P566, Q8VHY1, Q9CYH4	Gene names	Lix1
Domain Architecture	No domain graphic available
Description	Protein limb expression 1 homolog.

MYH13_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.000720 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	1504	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

NSF1C_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.011411 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNZ2, Q7Z533, Q9H102, Q9NVL9, Q9UI06	Gene names	NSFL1C
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

RRBP1_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.003946 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	1650	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

UBP30_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.458948 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

WDR20_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.004126 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	249	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

ASPP1_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.001521 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	956	Shared Neighborhood Hits	14
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

FOXJ2_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.000683 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	239	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

K0323_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.009520 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

MIB2_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.003129 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	438	Shared Neighborhood Hits	6
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

NGAP_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.004269 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	517	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

NSF1C_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.010918 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

REST_MOUSE
θ value	8.99809 (rank : 106)	NC score	-0.001726 (rank : 112)
Query Neighborhood Hits	109	Target Neighborhood Hits	1506	Shared Neighborhood Hits	11
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SP6_HUMAN
θ value	8.99809 (rank : 107)	NC score	-0.001666 (rank : 111)
Query Neighborhood Hits	109	Target Neighborhood Hits	700	Shared Neighborhood Hits	7
SwissProt Accessions	Q3SY56	Gene names	SP6, KLF14
Domain Architecture	No domain graphic available
Description	Transcription factor Sp6 (Krueppel-like factor 14).

VPS52_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.011307 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C754, Q6P4N7, Q8BQ15, Q9QWT6, Q9QWV2	Gene names	Vps52
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 52.

YETS2_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.004450 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	278	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

BRAP_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.059855 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	560	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.068650 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	409	Shared Neighborhood Hits	20
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

PRP5_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.085226 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

Hits sorted by NC score

USP9Y_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

USP9X_HUMAN
NC score	0.995257 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	161	Shared Neighborhood Hits	88
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
NC score	0.994715 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	171	Shared Neighborhood Hits	89
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP24_HUMAN
NC score	0.941066 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	96	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP34_MOUSE
NC score	0.813590 (rank : 5)	θ value	6.11685e-65 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	189	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_HUMAN
NC score	0.813321 (rank : 6)	θ value	2.4834e-66 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	210	Shared Neighborhood Hits	72
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP7_HUMAN
NC score	0.788483 (rank : 7)	θ value	5.59698e-26 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	93	Shared Neighborhood Hits	71
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP48_HUMAN
NC score	0.783156 (rank : 8)	θ value	5.584e-34 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP40_HUMAN
NC score	0.782016 (rank : 9)	θ value	1.62847e-25 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	81	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP48_MOUSE
NC score	0.779538 (rank : 10)	θ value	4.72714e-33 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP47_MOUSE
NC score	0.765869 (rank : 11)	θ value	1.79631e-32 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	135	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_HUMAN
NC score	0.763105 (rank : 12)	θ value	3.3877e-31 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP46_HUMAN
NC score	0.723573 (rank : 13)	θ value	5.60996e-18 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	81	Shared Neighborhood Hits	74
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.723573 (rank : 14)	θ value	5.60996e-18 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	81	Shared Neighborhood Hits	74
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP12_HUMAN
NC score	0.721870 (rank : 15)	θ value	6.20254e-17 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP18_HUMAN
NC score	0.713180 (rank : 16)	θ value	4.59992e-12 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	81	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UB17L_HUMAN
NC score	0.701529 (rank : 17)	θ value	1.80466e-16 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	83	Shared Neighborhood Hits	72
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBPW_MOUSE
NC score	0.698344 (rank : 18)	θ value	4.91457e-14 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP36_HUMAN
NC score	0.697959 (rank : 19)	θ value	1.63225e-17 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	232	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP18_MOUSE
NC score	0.677330 (rank : 20)	θ value	2.13673e-09 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	77	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP22_HUMAN
NC score	0.675370 (rank : 21)	θ value	4.02038e-16 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
NC score	0.673698 (rank : 22)	θ value	6.85773e-16 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	87	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
NC score	0.666919 (rank : 23)	θ value	4.44505e-15 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	162	Shared Neighborhood Hits	73
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP42_HUMAN
NC score	0.660990 (rank : 24)	θ value	3.40345e-15 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	445	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP3_MOUSE
NC score	0.660095 (rank : 25)	θ value	3.76295e-14 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP3_HUMAN
NC score	0.657820 (rank : 26)	θ value	3.18553e-13 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP20_HUMAN
NC score	0.652127 (rank : 27)	θ value	2.0648e-12 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP8_MOUSE
NC score	0.650594 (rank : 28)	θ value	2.13179e-17 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	362	Shared Neighborhood Hits	76
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP50_MOUSE
NC score	0.650230 (rank : 29)	θ value	3.89403e-11 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP33_HUMAN
NC score	0.644711 (rank : 30)	θ value	1.2105e-12 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	157	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP2_HUMAN
NC score	0.633968 (rank : 31)	θ value	1.47974e-10 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	84	Shared Neighborhood Hits	73
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_MOUSE
NC score	0.630600 (rank : 32)	θ value	1.133e-10 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP49_HUMAN
NC score	0.629940 (rank : 33)	θ value	2.0648e-12 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP44_HUMAN
NC score	0.627996 (rank : 34)	θ value	5.62301e-10 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP50_HUMAN
NC score	0.627091 (rank : 35)	θ value	1.38499e-08 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP49_MOUSE
NC score	0.626783 (rank : 36)	θ value	1.02475e-11 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	91	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP8_HUMAN
NC score	0.618054 (rank : 37)	θ value	9.56915e-18 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	751	Shared Neighborhood Hits	80
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP21_MOUSE
NC score	0.612577 (rank : 38)	θ value	1.99992e-07 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP21_HUMAN
NC score	0.610923 (rank : 39)	θ value	1.99992e-07 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP16_HUMAN
NC score	0.591604 (rank : 40)	θ value	3.77169e-06 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP38_HUMAN
NC score	0.578156 (rank : 41)	θ value	1.133e-10 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP35_HUMAN
NC score	0.566184 (rank : 42)	θ value	0.000270298 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	223	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP38_MOUSE
NC score	0.565477 (rank : 43)	θ value	4.30538e-10 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	100	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP15_HUMAN
NC score	0.554063 (rank : 44)	θ value	5.62301e-10 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
NC score	0.553998 (rank : 45)	θ value	7.34386e-10 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP11_HUMAN
NC score	0.550788 (rank : 46)	θ value	1.17247e-07 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP14_HUMAN
NC score	0.548923 (rank : 47)	θ value	4.92598e-06 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP1_HUMAN
NC score	0.546822 (rank : 48)	θ value	0.00509761 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	259	Shared Neighborhood Hits	74
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP31_HUMAN
NC score	0.546470 (rank : 49)	θ value	2.61198e-07 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	293	Shared Neighborhood Hits	75
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP43_MOUSE
NC score	0.538758 (rank : 50)	θ value	2.21117e-06 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	130	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP10_HUMAN
NC score	0.534135 (rank : 51)	θ value	5.81887e-07 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP43_HUMAN
NC score	0.533682 (rank : 52)	θ value	1.09739e-05 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	144	Shared Neighborhood Hits	73
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP4_HUMAN
NC score	0.531099 (rank : 53)	θ value	4.45536e-07 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP10_MOUSE
NC score	0.530778 (rank : 54)	θ value	1.69304e-06 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	150	Shared Neighborhood Hits	69
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP4_MOUSE
NC score	0.530146 (rank : 55)	θ value	1.69304e-06 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	90	Shared Neighborhood Hits	73
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP14_MOUSE
NC score	0.512750 (rank : 56)	θ value	0.000158464 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	87	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP37_HUMAN
NC score	0.500148 (rank : 57)	θ value	9.92553e-07 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	208	Shared Neighborhood Hits	73
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP28_MOUSE
NC score	0.480352 (rank : 58)	θ value	3.64472e-09 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	178	Shared Neighborhood Hits	74
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_HUMAN
NC score	0.479011 (rank : 59)	θ value	2.36244e-08 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	117	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP25_MOUSE
NC score	0.458991 (rank : 60)	θ value	2.61198e-07 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	116	Shared Neighborhood Hits	72
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

UBP30_HUMAN
NC score	0.458948 (rank : 61)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

SNUT2_MOUSE
NC score	0.458300 (rank : 62)	θ value	0.00020696 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBP25_HUMAN
NC score	0.457512 (rank : 63)	θ value	1.99992e-07 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	124	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

SNUT2_HUMAN
NC score	0.447961 (rank : 64)	θ value	0.00020696 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	79	Shared Neighborhood Hits	59
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP29_HUMAN
NC score	0.424684 (rank : 65)	θ value	0.000602161 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP32_HUMAN
NC score	0.423843 (rank : 66)	θ value	0.0330416 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	170	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP5_MOUSE
NC score	0.405072 (rank : 67)	θ value	0.00020696 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_HUMAN
NC score	0.402605 (rank : 68)	θ value	0.000786445 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	73
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP26_HUMAN
NC score	0.395026 (rank : 69)	θ value	0.00869519 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	108	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP6_HUMAN
NC score	0.394639 (rank : 70)	θ value	0.0252991 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	188	Shared Neighborhood Hits	75
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP29_MOUSE
NC score	0.392946 (rank : 71)	θ value	0.0193708 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP13_HUMAN
NC score	0.382969 (rank : 72)	θ value	0.00390308 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	99	Shared Neighborhood Hits	72
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP26_MOUSE
NC score	0.347276 (rank : 73)	θ value	0.00509761 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	107	Shared Neighborhood Hits	70
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

PRPC_HUMAN
NC score	0.087679 (rank : 74)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRP5_HUMAN
NC score	0.085226 (rank : 75)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	109	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

BRAP_MOUSE
NC score	0.068650 (rank : 76)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	109	Target Neighborhood Hits	409	Shared Neighborhood Hits	20
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

CHRC1_HUMAN
NC score	0.062447 (rank : 77)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRG0	Gene names	CHRAC1, CHRAC15
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15).

BRAP_HUMAN
NC score	0.059855 (rank : 78)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	109	Target Neighborhood Hits	560	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

PRP1_HUMAN
NC score	0.057199 (rank : 79)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	385	Shared Neighborhood Hits	9
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

BIRC6_HUMAN
NC score	0.039410 (rank : 80)	θ value	0.0961366 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

CF211_HUMAN
NC score	0.039200 (rank : 81)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H993, Q96FC6, Q9UFY5	Gene names	C6orf211
Domain Architecture	No domain graphic available
Description	UPF0364 protein C6orf211.

CI126_HUMAN
NC score	0.037518 (rank : 82)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N9R8, Q5T163, Q8N1I4	Gene names	C9orf126
Domain Architecture	No domain graphic available
Description	Protein C9orf126.

CI126_MOUSE
NC score	0.037502 (rank : 83)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C8N2, Q8C409, Q8C8K2	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf126 homolog.

LIX1_MOUSE
NC score	0.027639 (rank : 84)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P566, Q8VHY1, Q9CYH4	Gene names	Lix1
Domain Architecture	No domain graphic available
Description	Protein limb expression 1 homolog.

DMD_MOUSE
NC score	0.018024 (rank : 85)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	1111	Shared Neighborhood Hits	16
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

SMC2_MOUSE
NC score	0.015187 (rank : 86)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	1131	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

PAR10_HUMAN
NC score	0.014213 (rank : 87)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

SYNE1_HUMAN
NC score	0.013431 (rank : 88)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	1484	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

VPS52_HUMAN
NC score	0.013173 (rank : 89)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N1B4, Q53GR4, Q5JPA0, Q5SQW1, Q8IUN6, Q9NPT5	Gene names	VPS52, SACM2L
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 52 (SAC2 suppressor of actin mutations 2-like protein).

NSF1C_HUMAN
NC score	0.011411 (rank : 90)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNZ2, Q7Z533, Q9H102, Q9NVL9, Q9UI06	Gene names	NSFL1C
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

VPS52_MOUSE
NC score	0.011307 (rank : 91)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C754, Q6P4N7, Q8BQ15, Q9QWT6, Q9QWV2	Gene names	Vps52
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 52.

NSF1C_MOUSE
NC score	0.010918 (rank : 92)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

PYGO1_HUMAN
NC score	0.010458 (rank : 93)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

K0323_HUMAN
NC score	0.009520 (rank : 94)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

PPE1_HUMAN
NC score	0.008725 (rank : 95)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	137	Shared Neighborhood Hits	2
SwissProt Accessions	O14829, O15253, Q9NU21, Q9UJH0	Gene names	PPEF1, PPEF, PPP7C
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 1 (EC 3.1.3.16) (PPEF-1) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7).

STON2_HUMAN
NC score	0.007207 (rank : 96)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

SMC2_HUMAN
NC score	0.005205 (rank : 97)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	1405	Shared Neighborhood Hits	17
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

YETS2_MOUSE
NC score	0.004450 (rank : 98)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	278	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

NGAP_HUMAN
NC score	0.004269 (rank : 99)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	517	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

WDR20_HUMAN
NC score	0.004126 (rank : 100)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	249	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

RRBP1_MOUSE
NC score	0.003946 (rank : 101)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	1650	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

BRPF3_HUMAN
NC score	0.003628 (rank : 102)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	217	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

MIB2_HUMAN
NC score	0.003129 (rank : 103)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	438	Shared Neighborhood Hits	6
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

KIF1C_MOUSE
NC score	0.002612 (rank : 104)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	171	Shared Neighborhood Hits	5
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

ASPP1_HUMAN
NC score	0.001521 (rank : 105)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	956	Shared Neighborhood Hits	14
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ATBF1_HUMAN
NC score	0.001298 (rank : 106)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	1547	Shared Neighborhood Hits	9
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

MYH13_HUMAN
NC score	0.000720 (rank : 107)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	1504	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

FOXJ2_HUMAN
NC score	0.000683 (rank : 108)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	239	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

SP6_MOUSE
NC score	0.000208 (rank : 109)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	704	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ESX2, Q6VM22	Gene names	Sp6, Epfn, Klf14
Domain Architecture	No domain graphic available
Description	Transcription factor Sp6 (Krueppel-like factor 14) (Epiprofin).

ZN516_HUMAN
NC score	-0.001075 (rank : 110)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	854	Shared Neighborhood Hits	7
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

SP6_HUMAN
NC score	-0.001666 (rank : 111)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	700	Shared Neighborhood Hits	7
SwissProt Accessions	Q3SY56	Gene names	SP6, KLF14
Domain Architecture	No domain graphic available
Description	Transcription factor Sp6 (Krueppel-like factor 14).

REST_MOUSE
NC score	-0.001726 (rank : 112)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	1506	Shared Neighborhood Hits	11
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.