Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : BIRC6_HUMAN

For an explanation of this page, click here

BIRC6_HUMAN
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BIRC6_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

BIRC4_HUMAN
θ value	2.0648e-12 (rank : 2)	NC score	0.410027 (rank : 53)
Query Neighborhood Hits	161	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC4_MOUSE
θ value	4.59992e-12 (rank : 3)	NC score	0.409424 (rank : 54)
Query Neighborhood Hits	161	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

UBE2A_HUMAN
θ value	4.59992e-12 (rank : 4)	NC score	0.606817 (rank : 4)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P49459, Q4TTG1, Q96FX4	Gene names	UBE2A, RAD6A
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 A (EC 6.3.2.19) (Ubiquitin-protein ligase A) (Ubiquitin carrier protein A) (HR6A) (hHR6A).

UBE2A_MOUSE
θ value	4.59992e-12 (rank : 5)	NC score	0.606817 (rank : 5)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z255	Gene names	Ube2a, Rad6a
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 A (EC 6.3.2.19) (Ubiquitin-protein ligase A) (Ubiquitin carrier protein A) (HR6A) (mHR6A).

BIRC5_MOUSE
θ value	1.33837e-11 (rank : 6)	NC score	0.478743 (rank : 49)
Query Neighborhood Hits	161	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

UBE2B_HUMAN
θ value	1.74796e-11 (rank : 7)	NC score	0.605314 (rank : 6)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P63146, P23567, Q4PJ15, Q9D0J6	Gene names	UBE2B, RAD6B
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 B (EC 6.3.2.19) (Ubiquitin-protein ligase B) (Ubiquitin carrier protein B) (HR6B) (hHR6B) (E2-17 kDa).

UBE2B_MOUSE
θ value	1.74796e-11 (rank : 8)	NC score	0.605314 (rank : 7)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P63147, P23567, Q3UGS2, Q9D0J6	Gene names	Ube2b, Rad6b
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 B (EC 6.3.2.19) (Ubiquitin-protein ligase B) (Ubiquitin carrier protein B) (HR6B) (E214K).

BIRC5_HUMAN
θ value	8.67504e-11 (rank : 9)	NC score	0.473040 (rank : 50)
Query Neighborhood Hits	161	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

UBE2T_HUMAN
θ value	1.47974e-10 (rank : 10)	NC score	0.596853 (rank : 14)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NPD8	Gene names	UBE2T
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 T (EC 6.3.2.19) (Ubiquitin-protein ligase T) (Ubiquitin carrier protein T).

BIRC2_HUMAN
θ value	9.59137e-10 (rank : 11)	NC score	0.380637 (rank : 56)
Query Neighborhood Hits	161	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC3_HUMAN
θ value	9.59137e-10 (rank : 12)	NC score	0.380896 (rank : 55)
Query Neighborhood Hits	161	Target Neighborhood Hits	133	Shared Neighborhood Hits	17
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

UB2G2_HUMAN
θ value	1.25267e-09 (rank : 13)	NC score	0.608468 (rank : 2)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P60604, P56554	Gene names	UBE2G2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G2 (EC 6.3.2.19) (Ubiquitin-protein ligase G2) (Ubiquitin carrier protein G2).

UB2G2_MOUSE
θ value	1.25267e-09 (rank : 14)	NC score	0.608468 (rank : 3)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P60605, P56554	Gene names	Ube2g2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G2 (EC 6.3.2.19) (Ubiquitin-protein ligase G2) (Ubiquitin carrier protein G2).

BIRC2_MOUSE
θ value	1.63604e-09 (rank : 15)	NC score	0.379131 (rank : 57)
Query Neighborhood Hits	161	Target Neighborhood Hits	137	Shared Neighborhood Hits	17
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

UB2R1_HUMAN
θ value	2.13673e-09 (rank : 16)	NC score	0.598606 (rank : 11)
Query Neighborhood Hits	161	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	P49427	Gene names	CDC34, UBE2R1
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-32 kDa complementing (EC 6.3.2.19) (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (E2-CDC34).

UB2R1_MOUSE
θ value	2.13673e-09 (rank : 17)	NC score	0.598701 (rank : 10)
Query Neighborhood Hits	161	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CFI2, Q505K8	Gene names	Cdc34
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-32 kDa complementing (EC 6.3.2.19) (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (E2-CDC34).

UB2G1_HUMAN
θ value	2.79066e-09 (rank : 18)	NC score	0.597347 (rank : 12)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P62253, Q99462	Gene names	UBE2G1, UBE2G
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G1 (EC 6.3.2.19) (Ubiquitin-protein ligase G1) (Ubiquitin carrier protein G1) (E217K) (UBC7).

UB2G1_MOUSE
θ value	2.79066e-09 (rank : 19)	NC score	0.597347 (rank : 13)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P62254, Q99462	Gene names	Ube2g1, Ube2g
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G1 (EC 6.3.2.19) (Ubiquitin-protein ligase G1) (Ubiquitin carrier protein G1) (E217K) (UBC7).

UBE2T_MOUSE
θ value	3.64472e-09 (rank : 20)	NC score	0.590668 (rank : 17)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CQ37	Gene names	Ube2t
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 T (EC 6.3.2.19) (Ubiquitin-protein ligase T) (Ubiquitin carrier protein T).

BIRC3_MOUSE
θ value	4.76016e-09 (rank : 21)	NC score	0.378831 (rank : 58)
Query Neighborhood Hits	161	Target Neighborhood Hits	113	Shared Neighborhood Hits	18
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

UBC9_HUMAN
θ value	4.76016e-09 (rank : 22)	NC score	0.601797 (rank : 8)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	P63279, P50550, Q15698, Q86VB3	Gene names	UBE2I, UBC9, UBCE9
Domain Architecture	No domain graphic available
Description	SUMO-1-conjugating enzyme UBC9 (EC 6.3.2.19) (SUMO-1-protein ligase) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (Ubiquitin carrier protein I) (Ubiquitin carrier protein 9) (p18).

UBC9_MOUSE
θ value	4.76016e-09 (rank : 23)	NC score	0.601797 (rank : 9)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	P63280, P50550, Q15698, Q86VB3	Gene names	Ube2i, Ubc9, Ubce9
Domain Architecture	No domain graphic available
Description	SUMO-1-conjugating enzyme UBC9 (EC 6.3.2.19) (SUMO-1-protein ligase) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (Ubiquitin carrier protein I) (Ubiquitin carrier protein 9) (mUBC9).

UBE2N_HUMAN
θ value	6.21693e-09 (rank : 24)	NC score	0.594026 (rank : 15)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P61088, Q16781	Gene names	UBE2N, BLU
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 N (EC 6.3.2.19) (Ubiquitin-protein ligase N) (Ubiquitin carrier protein N) (Ubc13) (Bendless-like ubiquitin-conjugating enzyme).

UBE2N_MOUSE
θ value	6.21693e-09 (rank : 25)	NC score	0.594026 (rank : 16)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P61089, Q16781, Q6ZWZ0, Q9DAJ6	Gene names	Ube2n, Blu
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 N (EC 6.3.2.19) (Ubiquitin-protein ligase N) (Ubiquitin carrier protein N) (Ubc13) (Bendless-like ubiquitin-conjugating enzyme).

BIR1B_MOUSE
θ value	4.0297e-08 (rank : 26)	NC score	0.332930 (rank : 61)
Query Neighborhood Hits	161	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

UB2D2_HUMAN
θ value	4.0297e-08 (rank : 27)	NC score	0.575811 (rank : 21)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	P62837, P51669	Gene names	UBE2D2, UBC4, UBCH5B
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 D2 (EC 6.3.2.19) (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2).

UB2D2_MOUSE
θ value	4.0297e-08 (rank : 28)	NC score	0.575811 (rank : 22)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	P62838, P51669	Gene names	Ube2d2, Ubc4
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 D2 (EC 6.3.2.19) (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2).

UB2D3_HUMAN
θ value	4.0297e-08 (rank : 29)	NC score	0.575688 (rank : 23)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	P61077, P47986, Q6IB88, Q6NXS4	Gene names	UBE2D3, UBCH5C
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D3 (EC 6.3.2.19) (Ubiquitin-protein ligase D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (E2(17)KB 3).

UB2D3_MOUSE
θ value	4.0297e-08 (rank : 30)	NC score	0.575688 (rank : 24)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	P61079	Gene names	Ube2d3
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D3 (EC 6.3.2.19) (Ubiquitin-protein ligase D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (E2(17)KB 3).

UB2L6_MOUSE
θ value	6.87365e-08 (rank : 31)	NC score	0.585967 (rank : 20)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QZU9, Q922F1, Q9CQN0	Gene names	Ube2l6, Ubce8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 L6 (EC 6.3.2.19) (Ubiquitin-protein ligase L6) (Ubiquitin carrier protein L6) (UbcM8).

BIRC7_HUMAN
θ value	1.53129e-07 (rank : 32)	NC score	0.354464 (rank : 60)
Query Neighborhood Hits	161	Target Neighborhood Hits	185	Shared Neighborhood Hits	18
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

UBE2S_HUMAN
θ value	1.53129e-07 (rank : 33)	NC score	0.587950 (rank : 19)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q16763, Q9BTC1	Gene names	UBE2S, E2EPF
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 S (EC 6.3.2.19) (Ubiquitin-protein ligase S) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (E2-EPF5).

UBE2S_MOUSE
θ value	1.53129e-07 (rank : 34)	NC score	0.588078 (rank : 18)
Query Neighborhood Hits	161	Target Neighborhood Hits	54	Shared Neighborhood Hits	50
SwissProt Accessions	Q921J4, Q3U4V7	Gene names	Ube2s, E2epf
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 S (EC 6.3.2.19) (Ubiquitin-protein ligase S) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (E2-EPF5).

UB2D1_HUMAN
θ value	3.41135e-07 (rank : 35)	NC score	0.572369 (rank : 27)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P51668	Gene names	UBE2D1, UBCH5, UBCH5A
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D1 (EC 6.3.2.19) (Ubiquitin-protein ligase D1) (Ubiquitin carrier protein D1) (UbcH5) (Ubiquitin- conjugating enzyme E2-17 kDa 1) (E2(17)KB 1).

UB2D1_MOUSE
θ value	3.41135e-07 (rank : 36)	NC score	0.572369 (rank : 28)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P61080	Gene names	Ube2d1
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D1 (EC 6.3.2.19) (Ubiquitin-protein ligase D1) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (E2(17)KB 1).

BIRC1_HUMAN
θ value	7.59969e-07 (rank : 37)	NC score	0.331518 (rank : 62)
Query Neighborhood Hits	161	Target Neighborhood Hits	61	Shared Neighborhood Hits	18
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1F_MOUSE
θ value	2.21117e-06 (rank : 38)	NC score	0.325611 (rank : 64)
Query Neighborhood Hits	161	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1A_MOUSE
θ value	2.88788e-06 (rank : 39)	NC score	0.324270 (rank : 66)
Query Neighborhood Hits	161	Target Neighborhood Hits	94	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1E_MOUSE
θ value	2.88788e-06 (rank : 40)	NC score	0.325691 (rank : 63)
Query Neighborhood Hits	161	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1G_MOUSE
θ value	2.88788e-06 (rank : 41)	NC score	0.325202 (rank : 65)
Query Neighborhood Hits	161	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIRC8_HUMAN
θ value	6.43352e-06 (rank : 42)	NC score	0.371664 (rank : 59)
Query Neighborhood Hits	161	Target Neighborhood Hits	121	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

UB2L3_HUMAN
θ value	6.43352e-06 (rank : 43)	NC score	0.575233 (rank : 25)
Query Neighborhood Hits	161	Target Neighborhood Hits	63	Shared Neighborhood Hits	50
SwissProt Accessions	P68036, P51966, P70653, Q9HAV1	Gene names	UBE2L3, UBCE7, UBCH7
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcH7) (E2-F1) (L-UBC).

UB2L3_MOUSE
θ value	6.43352e-06 (rank : 44)	NC score	0.575233 (rank : 26)
Query Neighborhood Hits	161	Target Neighborhood Hits	63	Shared Neighborhood Hits	50
SwissProt Accessions	P68037, P51966, P70653, Q9HAV1	Gene names	Ube2l3, Ubce7
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcM4).

UBE2C_HUMAN
θ value	1.43324e-05 (rank : 45)	NC score	0.568887 (rank : 30)
Query Neighborhood Hits	161	Target Neighborhood Hits	54	Shared Neighborhood Hits	50
SwissProt Accessions	O00762	Gene names	UBE2C, UBCH10
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 C (EC 6.3.2.19) (Ubiquitin-protein ligase C) (Ubiquitin carrier protein C) (UbcH10).

UB2L6_HUMAN
θ value	2.44474e-05 (rank : 46)	NC score	0.569208 (rank : 29)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	O14933, Q9UEZ0	Gene names	UBE2L6, UBCH8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 L6 (EC 6.3.2.19) (Ubiquitin-protein ligase L6) (Ubiquitin carrier protein L6) (UbcH8) (Retinoic acid- induced gene B protein) (RIG-B).

UB2E3_HUMAN
θ value	3.19293e-05 (rank : 47)	NC score	0.551164 (rank : 34)
Query Neighborhood Hits	161	Target Neighborhood Hits	62	Shared Neighborhood Hits	50
SwissProt Accessions	Q969T4, Q5U0R7, Q7Z4W4	Gene names	UBE2E3, UBCE4, UBCH9
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E3 (EC 6.3.2.19) (Ubiquitin-protein ligase E3) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (UbcH9) (UbcM2).

UB2E3_MOUSE
θ value	3.19293e-05 (rank : 48)	NC score	0.551164 (rank : 35)
Query Neighborhood Hits	161	Target Neighborhood Hits	62	Shared Neighborhood Hits	50
SwissProt Accessions	P52483, O09180, Q3TI00, Q91X63	Gene names	Ube2e3, Ubce4, Ubcm2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E3 (EC 6.3.2.19) (Ubiquitin-protein ligase E3) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (UbcM2).

UB2E2_HUMAN
θ value	4.1701e-05 (rank : 49)	NC score	0.549768 (rank : 36)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q96LR5	Gene names	UBE2E2, UBCH8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2) (UbcH8).

UB2E2_MOUSE
θ value	4.1701e-05 (rank : 50)	NC score	0.548978 (rank : 37)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q91W82	Gene names	Ube2e2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2).

UBC1_HUMAN
θ value	5.44631e-05 (rank : 51)	NC score	0.554990 (rank : 32)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	50
SwissProt Accessions	P61086, O54806, P27924, Q16721, Q9CVV9, Q9Y2D3	Gene names	HIP2, LIG
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-25 kDa (EC 6.3.2.19) (Ubiquitin- protein ligase) (Ubiquitin carrier protein) (E2(25K)) (Huntingtin- interacting protein 2) (HIP-2).

UBC1_MOUSE
θ value	5.44631e-05 (rank : 52)	NC score	0.554990 (rank : 33)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	50
SwissProt Accessions	P61087, O54806, P27924, Q16721, Q9CVV9	Gene names	Hip2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-25 kDa (EC 6.3.2.19) (Ubiquitin- protein ligase) (Ubiquitin carrier protein) (E2(25K)) (Huntingtin- interacting protein 2) (HIP-2).

UBE2C_MOUSE
θ value	9.29e-05 (rank : 53)	NC score	0.564860 (rank : 31)
Query Neighborhood Hits	161	Target Neighborhood Hits	54	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D1C1, Q3TUJ0	Gene names	Ube2c, Ubch10
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 C (EC 6.3.2.19) (Ubiquitin-protein ligase C) (Ubiquitin carrier protein C) (UbcH10).

UB2E1_HUMAN
θ value	0.000121331 (rank : 54)	NC score	0.547314 (rank : 38)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P51965	Gene names	UBE2E1, UBCH6
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E1 (EC 6.3.2.19) (Ubiquitin-protein ligase E1) (Ubiquitin carrier protein E1) (UbcH6).

UB2E1_MOUSE
θ value	0.000121331 (rank : 55)	NC score	0.545927 (rank : 39)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P52482	Gene names	Ube2e1, Ubce5, Ubcm3
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E1 (EC 6.3.2.19) (Ubiquitin-protein ligase E1) (Ubiquitin carrier protein E1) (UbcM3).

UBC12_HUMAN
θ value	0.000786445 (rank : 56)	NC score	0.542311 (rank : 40)
Query Neighborhood Hits	161	Target Neighborhood Hits	48	Shared Neighborhood Hits	46
SwissProt Accessions	P61081, O76069, Q8VC50	Gene names	UBE2M, UBC12
Domain Architecture
Description	NEDD8-conjugating enzyme Ubc12 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme E2 M) (NEDD8 protein ligase) (NEDD8 carrier protein).

UBC12_MOUSE
θ value	0.000786445 (rank : 57)	NC score	0.542311 (rank : 41)
Query Neighborhood Hits	161	Target Neighborhood Hits	48	Shared Neighborhood Hits	46
SwissProt Accessions	P61082, O76069, Q8VC50	Gene names	Ube2m, Ubc-rs2, Ubc12
Domain Architecture
Description	NEDD8-conjugating enzyme Ubc12 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme E2 M) (NEDD8 protein ligase) (NEDD8 carrier protein).

UB2J2_HUMAN
θ value	0.00298849 (rank : 58)	NC score	0.486000 (rank : 48)
Query Neighborhood Hits	161	Target Neighborhood Hits	54	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N2K1, Q96N26, Q96T84	Gene names	UBE2J2, NCUBE2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J2 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE2).

UB2J2_MOUSE
θ value	0.00298849 (rank : 59)	NC score	0.488205 (rank : 47)
Query Neighborhood Hits	161	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P073, Q8C6A1, Q91Y64, Q9CWY5, Q9DC18, Q9QX58	Gene names	Ube2j2, Ncube2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J2 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE2).

UB2J1_HUMAN
θ value	0.0113563 (rank : 60)	NC score	0.451044 (rank : 51)
Query Neighborhood Hits	161	Target Neighborhood Hits	61	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y385, Q5W0N4, Q9BZ32, Q9NQL3, Q9NY66, Q9P011, Q9P0S0, Q9UF10	Gene names	UBE2J1, NCUBE1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HSUBC6e).

UB2J1_MOUSE
θ value	0.0113563 (rank : 61)	NC score	0.450171 (rank : 52)
Query Neighborhood Hits	161	Target Neighborhood Hits	74	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JJZ4, Q9DC92	Gene names	Ube2j1, Ncube1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1).

IFT74_HUMAN
θ value	0.0431538 (rank : 62)	NC score	0.032802 (rank : 90)
Query Neighborhood Hits	161	Target Neighborhood Hits	949	Shared Neighborhood Hits	28
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

UBE2H_HUMAN
θ value	0.0563607 (rank : 63)	NC score	0.533438 (rank : 42)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P62256, P37286	Gene names	UBE2H
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) (Ubiquitin-protein ligase H) (Ubiquitin carrier protein H) (UbcH2) (E2-20K).

UBE2H_MOUSE
θ value	0.0563607 (rank : 64)	NC score	0.533438 (rank : 43)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P62257, P37286	Gene names	Ube2h
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) (Ubiquitin-protein ligase H) (Ubiquitin carrier protein H) (UBCH2) (E2-20K).

UBE2W_MOUSE
θ value	0.0736092 (rank : 65)	NC score	0.511142 (rank : 45)
Query Neighborhood Hits	161	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VDW4, Q9D5H3	Gene names	Ube2w
Domain Architecture	No domain graphic available
Description	Probable ubiquitin-conjugating enzyme E2 W (EC 6.3.2.19) (Ubiquitin- protein ligase W) (Ubiquitin carrier protein W).

UBE2W_HUMAN
θ value	0.0961366 (rank : 66)	NC score	0.509921 (rank : 46)
Query Neighborhood Hits	161	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q96B02, Q9H823, Q9HAG6, Q9NV07	Gene names	UBE2W
Domain Architecture	No domain graphic available
Description	Probable ubiquitin-conjugating enzyme E2 W (EC 6.3.2.19) (Ubiquitin- protein ligase W) (Ubiquitin carrier protein W).

USP9Y_HUMAN
θ value	0.0961366 (rank : 67)	NC score	0.039410 (rank : 85)
Query Neighborhood Hits	161	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

ARRS_MOUSE
θ value	0.279714 (rank : 68)	NC score	0.034500 (rank : 89)
Query Neighborhood Hits	161	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P20443, Q91W62	Gene names	Sag
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

BCL9_HUMAN
θ value	0.365318 (rank : 69)	NC score	0.020920 (rank : 109)
Query Neighborhood Hits	161	Target Neighborhood Hits	1008	Shared Neighborhood Hits	8
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

LRC45_HUMAN
θ value	0.365318 (rank : 70)	NC score	0.022449 (rank : 105)
Query Neighborhood Hits	161	Target Neighborhood Hits	933	Shared Neighborhood Hits	23
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

FOXP4_HUMAN
θ value	0.47712 (rank : 71)	NC score	0.016191 (rank : 122)
Query Neighborhood Hits	161	Target Neighborhood Hits	246	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

LRRF1_HUMAN
θ value	0.47712 (rank : 72)	NC score	0.031924 (rank : 91)
Query Neighborhood Hits	161	Target Neighborhood Hits	625	Shared Neighborhood Hits	15
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

BPAEA_HUMAN
θ value	0.62314 (rank : 73)	NC score	0.016062 (rank : 124)
Query Neighborhood Hits	161	Target Neighborhood Hits	1369	Shared Neighborhood Hits	30
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DYH5_MOUSE
θ value	0.62314 (rank : 74)	NC score	0.021898 (rank : 106)
Query Neighborhood Hits	161	Target Neighborhood Hits	286	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

FEZ2_HUMAN
θ value	0.62314 (rank : 75)	NC score	0.035797 (rank : 88)
Query Neighborhood Hits	161	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHY8, Q76LN0, Q99690	Gene names	FEZ2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

SCFD2_MOUSE
θ value	0.62314 (rank : 76)	NC score	0.039910 (rank : 83)
Query Neighborhood Hits	161	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BTY8, Q3USN5, Q8BFV9, Q8BKU5, Q8BKZ0, Q8BTP6, Q8BTQ9, Q8BXI1, Q8BXS0, Q8BZ58	Gene names	Scfd2, Stxbp1l1
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 2 (Syntaxin-binding protein 1- like 1) (Neuronal Sec1).

UBE2U_HUMAN
θ value	0.62314 (rank : 77)	NC score	0.515188 (rank : 44)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q5VVX9, Q8N1D4	Gene names	UBE2U
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 U (EC 6.3.2.19) (Ubiquitin-protein ligase U) (Ubiquitin carrier protein U).

ANR18_HUMAN
θ value	0.813845 (rank : 78)	NC score	0.014644 (rank : 132)
Query Neighborhood Hits	161	Target Neighborhood Hits	1106	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

CI093_HUMAN
θ value	0.813845 (rank : 79)	NC score	0.018753 (rank : 115)
Query Neighborhood Hits	161	Target Neighborhood Hits	1088	Shared Neighborhood Hits	25
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

P3H3_HUMAN
θ value	0.813845 (rank : 80)	NC score	0.023744 (rank : 103)
Query Neighborhood Hits	161	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IVL6, Q13512, Q15740, Q66K32, Q6NX61, Q7L2T1	Gene names	LEPREL2, P3H3
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 3 precursor (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B).

WDR75_HUMAN
θ value	0.813845 (rank : 81)	NC score	0.036436 (rank : 87)
Query Neighborhood Hits	161	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWA0, Q96J10, Q9H8U8, Q9H9U5, Q9H9V8, Q9UIX2	Gene names	WDR75
Domain Architecture	No domain graphic available
Description	WD repeat protein 75.

CLN3_HUMAN
θ value	1.06291 (rank : 82)	NC score	0.038358 (rank : 86)
Query Neighborhood Hits	161	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q13286, O00668, Q9UP09, Q9UP11, Q9UP12, Q9UP13, Q9UP14	Gene names	CLN3, BTS
Domain Architecture
Description	Protein CLN3 (Battenin) (Batten disease protein).

GOGA3_MOUSE
θ value	1.06291 (rank : 83)	NC score	0.014666 (rank : 131)
Query Neighborhood Hits	161	Target Neighborhood Hits	1437	Shared Neighborhood Hits	33
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

K0423_HUMAN
θ value	1.06291 (rank : 84)	NC score	0.028832 (rank : 95)
Query Neighborhood Hits	161	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

MYH11_HUMAN
θ value	1.06291 (rank : 85)	NC score	0.009670 (rank : 151)
Query Neighborhood Hits	161	Target Neighborhood Hits	1806	Shared Neighborhood Hits	34
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PK3CB_HUMAN
θ value	1.06291 (rank : 86)	NC score	0.019056 (rank : 113)
Query Neighborhood Hits	161	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

TS101_HUMAN
θ value	1.06291 (rank : 87)	NC score	0.039858 (rank : 84)
Query Neighborhood Hits	161	Target Neighborhood Hits	359	Shared Neighborhood Hits	12
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

VWF_MOUSE
θ value	1.06291 (rank : 88)	NC score	0.012966 (rank : 140)
Query Neighborhood Hits	161	Target Neighborhood Hits	381	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CLSPN_MOUSE
θ value	1.38821 (rank : 89)	NC score	0.026876 (rank : 97)
Query Neighborhood Hits	161	Target Neighborhood Hits	292	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

PLCB1_HUMAN
θ value	1.38821 (rank : 90)	NC score	0.023766 (rank : 102)
Query Neighborhood Hits	161	Target Neighborhood Hits	614	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

SPTN5_HUMAN
θ value	1.38821 (rank : 91)	NC score	0.013786 (rank : 135)
Query Neighborhood Hits	161	Target Neighborhood Hits	674	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

CCD62_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.023229 (rank : 104)
Query Neighborhood Hits	161	Target Neighborhood Hits	631	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CRGB_HUMAN
θ value	1.81305 (rank : 93)	NC score	0.013300 (rank : 138)
Query Neighborhood Hits	161	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P07316	Gene names	CRYGB, CRYG2
Domain Architecture
Description	Gamma crystallin B (Gamma crystallin 1-2).

OX1R_HUMAN
θ value	1.81305 (rank : 94)	NC score	-0.000020 (rank : 175)
Query Neighborhood Hits	161	Target Neighborhood Hits	909	Shared Neighborhood Hits	4
SwissProt Accessions	O43613	Gene names	HCRTR1
Domain Architecture
Description	Orexin receptor type 1 (Ox1r) (Hypocretin receptor type 1).

PLCB1_MOUSE
θ value	1.81305 (rank : 95)	NC score	0.024984 (rank : 100)
Query Neighborhood Hits	161	Target Neighborhood Hits	531	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

IFT74_MOUSE
θ value	2.36792 (rank : 96)	NC score	0.025839 (rank : 98)
Query Neighborhood Hits	161	Target Neighborhood Hits	939	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

RABE1_MOUSE
θ value	2.36792 (rank : 97)	NC score	0.017896 (rank : 116)
Query Neighborhood Hits	161	Target Neighborhood Hits	1105	Shared Neighborhood Hits	27
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

TM108_HUMAN
θ value	2.36792 (rank : 98)	NC score	0.025073 (rank : 99)
Query Neighborhood Hits	161	Target Neighborhood Hits	166	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

USP9X_HUMAN
θ value	2.36792 (rank : 99)	NC score	0.031056 (rank : 93)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
θ value	2.36792 (rank : 100)	NC score	0.031155 (rank : 92)
Query Neighborhood Hits	161	Target Neighborhood Hits	171	Shared Neighborhood Hits	5
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

WD51B_MOUSE
θ value	2.36792 (rank : 101)	NC score	0.007186 (rank : 159)
Query Neighborhood Hits	161	Target Neighborhood Hits	321	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHD1	Gene names	Wdr51b
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

GP176_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.005556 (rank : 166)
Query Neighborhood Hits	161	Target Neighborhood Hits	539	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

HPS5_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.021531 (rank : 107)
Query Neighborhood Hits	161	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPZ3, O95942, Q8N4U0	Gene names	HPS5, AIBP63, KIAA1017
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein (Alpha-integrin-binding protein 63) (Ruby-eye protein 2 homolog) (Ru2).

P5CS_MOUSE
θ value	3.0926 (rank : 104)	NC score	0.027896 (rank : 96)
Query Neighborhood Hits	161	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z110, Q9R1P6	Gene names	Aldh18a1, P5cs, Pycs
Domain Architecture
Description	Delta 1-pyrroline-5-carboxylate synthetase (P5CS) (Aldehyde dehydrogenase 18 family member A1) [Includes: Glutamate 5-kinase (EC 2.7.2.11) (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)].

PKD1_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.011053 (rank : 147)
Query Neighborhood Hits	161	Target Neighborhood Hits	387	Shared Neighborhood Hits	3
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

PKHA6_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.013580 (rank : 136)
Query Neighborhood Hits	161	Target Neighborhood Hits	591	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SFRP5_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.017273 (rank : 119)
Query Neighborhood Hits	161	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

WD51B_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.006631 (rank : 161)
Query Neighborhood Hits	161	Target Neighborhood Hits	335	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

ARRS_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.023851 (rank : 101)
Query Neighborhood Hits	161	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P10523, Q53SV3, Q99858	Gene names	SAG
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

FAS_MOUSE
θ value	4.03905 (rank : 110)	NC score	0.014881 (rank : 130)
Query Neighborhood Hits	161	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P19096, Q6PB72, Q8C4Z0, Q9EQR0	Gene names	Fasn
Domain Architecture	No domain graphic available
Description	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S- acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S- malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.10); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)].

K1C14_MOUSE
θ value	4.03905 (rank : 111)	NC score	0.006409 (rank : 163)
Query Neighborhood Hits	161	Target Neighborhood Hits	501	Shared Neighborhood Hits	19
SwissProt Accessions	Q61781, Q91VQ4	Gene names	Krt14, Krt1-14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

PK3CB_MOUSE
θ value	4.03905 (rank : 112)	NC score	0.015391 (rank : 128)
Query Neighborhood Hits	161	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PXDC1_MOUSE
θ value	4.03905 (rank : 113)	NC score	0.016641 (rank : 121)
Query Neighborhood Hits	161	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q91ZV7, Q8BM20, Q9CWV5	Gene names	Plxdc1, Tem7
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 1 precursor (Tumor endothelial marker 7).

RCOR1_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.017623 (rank : 117)
Query Neighborhood Hits	161	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKL0, Q15044, Q6P2I9, Q86VG5	Gene names	RCOR1, KIAA0071, RCOR
Domain Architecture	No domain graphic available
Description	REST corepressor 1 (Protein CoREST).

RCOR1_MOUSE
θ value	4.03905 (rank : 115)	NC score	0.017437 (rank : 118)
Query Neighborhood Hits	161	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CFE3, Q3V092, Q8BK28, Q8CHI2	Gene names	Rcor1, D12Wsu95e, Kiaa0071
Domain Architecture	No domain graphic available
Description	REST corepressor 1 (Protein CoREST).

S35B2_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.019651 (rank : 111)
Query Neighborhood Hits	161	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TB61, Q5T9W1, Q5T9W2, Q7Z2G3, Q8NBK6, Q96AR6	Gene names	SLC35B2, PAPST1
Domain Architecture	No domain graphic available
Description	Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (PAPS transporter 1) (Solute carrier family 35 member B2) (Putative MAPK-activating protein PM15) (Putative NF-kappa-B-activating protein 48).

TNR1B_MOUSE
θ value	4.03905 (rank : 117)	NC score	0.013041 (rank : 139)
Query Neighborhood Hits	161	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TRAIP_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.015653 (rank : 126)
Query Neighborhood Hits	161	Target Neighborhood Hits	780	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

ABCAD_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.005167 (rank : 168)
Query Neighborhood Hits	161	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ANR38_MOUSE
θ value	5.27518 (rank : 120)	NC score	0.011000 (rank : 148)
Query Neighborhood Hits	161	Target Neighborhood Hits	512	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CT2NL_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.011526 (rank : 146)
Query Neighborhood Hits	161	Target Neighborhood Hits	1059	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

FA45B_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.016190 (rank : 123)
Query Neighborhood Hits	161	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NSW5, Q9NZ36	Gene names	FAM45B
Domain Architecture	No domain graphic available
Description	Protein FAM45B.

GAK_HUMAN
θ value	5.27518 (rank : 123)	NC score	-0.002963 (rank : 176)
Query Neighborhood Hits	161	Target Neighborhood Hits	1028	Shared Neighborhood Hits	3
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

LARGE_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.011970 (rank : 144)
Query Neighborhood Hits	161	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1M7, Q497S9, Q6P7U2, Q80TW0	Gene names	Large, Kiaa0609, Large1
Domain Architecture
Description	Glycosyltransferase-like protein LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A).

LRC19_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.006561 (rank : 162)
Query Neighborhood Hits	161	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H756	Gene names	LRRC19
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 19 precursor.

MBD5_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.020878 (rank : 110)
Query Neighborhood Hits	161	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

SFRP1_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.014486 (rank : 133)
Query Neighborhood Hits	161	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

TBD_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.008308 (rank : 157)
Query Neighborhood Hits	161	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJT1, Q9BWG9, Q9H7Z8	Gene names	TUBD1, TUBD
Domain Architecture
Description	Tubulin delta chain (Delta tubulin).

TS101_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.031009 (rank : 94)
Query Neighborhood Hits	161	Target Neighborhood Hits	312	Shared Neighborhood Hits	11
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

BCL7C_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.013572 (rank : 137)
Query Neighborhood Hits	161	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

CCM2_MOUSE
θ value	6.88961 (rank : 131)	NC score	0.018957 (rank : 114)
Query Neighborhood Hits	161	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2Y9	Gene names	Ccm2, Osm
Domain Architecture	No domain graphic available
Description	Malcavernin (Cerebral cavernous malformations protein 2 homolog) (Osmosensing scaffold for MEKK3).

CEP63_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.012114 (rank : 143)
Query Neighborhood Hits	161	Target Neighborhood Hits	1005	Shared Neighborhood Hits	25
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CN037_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.014961 (rank : 129)
Query Neighborhood Hits	161	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

CT026_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.019332 (rank : 112)
Query Neighborhood Hits	161	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHU2, Q5TE18, Q8N5R9, Q96M59, Q9BQL2, Q9H127, Q9H128, Q9NQH4, Q9UFV8, Q9Y4V7	Gene names	C20orf26
Domain Architecture
Description	Uncharacterized protein C20orf26.

GAS8_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.010888 (rank : 149)
Query Neighborhood Hits	161	Target Neighborhood Hits	819	Shared Neighborhood Hits	20
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

MLH1_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.012835 (rank : 141)
Query Neighborhood Hits	161	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JK91, Q62454	Gene names	Mlh1
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

PAR14_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.009421 (rank : 152)
Query Neighborhood Hits	161	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PO6F1_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.002710 (rank : 171)
Query Neighborhood Hits	161	Target Neighborhood Hits	581	Shared Neighborhood Hits	5
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

PTRF_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.016049 (rank : 125)
Query Neighborhood Hits	161	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	O54724	Gene names	Ptrf
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor.

RABE1_HUMAN
θ value	6.88961 (rank : 140)	NC score	0.015642 (rank : 127)
Query Neighborhood Hits	161	Target Neighborhood Hits	1104	Shared Neighborhood Hits	27
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

SFRP5_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.014161 (rank : 134)
Query Neighborhood Hits	161	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

ANR15_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.007646 (rank : 158)
Query Neighborhood Hits	161	Target Neighborhood Hits	478	Shared Neighborhood Hits	12
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

BRCA1_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.006693 (rank : 160)
Query Neighborhood Hits	161	Target Neighborhood Hits	381	Shared Neighborhood Hits	4
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRD3_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.005543 (rank : 167)
Query Neighborhood Hits	161	Target Neighborhood Hits	369	Shared Neighborhood Hits	8
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

CAC1I_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.003399 (rank : 170)
Query Neighborhood Hits	161	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CCM2_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.017187 (rank : 120)
Query Neighborhood Hits	161	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSQ5, Q71RE5, Q8TAT4	Gene names	CCM2, C7orf22
Domain Architecture	No domain graphic available
Description	Malcavernin (Cerebral cavernous malformations 2 protein).

DNAI2_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.009060 (rank : 154)
Query Neighborhood Hits	161	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

EMR1_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.000743 (rank : 174)
Query Neighborhood Hits	161	Target Neighborhood Hits	382	Shared Neighborhood Hits	3
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.000772 (rank : 173)
Query Neighborhood Hits	161	Target Neighborhood Hits	349	Shared Neighborhood Hits	3
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

IF122_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.009114 (rank : 153)
Query Neighborhood Hits	161	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBG6	Gene names	IFT122, WDR10, WDR140
Domain Architecture
Description	Intraflagellar transport 122 homolog (WD repeat protein 10).

K0859_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.012169 (rank : 142)
Query Neighborhood Hits	161	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N6R0, O94940, Q5TGP9, Q5TGQ0, Q8N2P8, Q96J11, Q96SQ0, Q9Y2Z1, Q9Y3M6	Gene names	KIAA0859
Domain Architecture	No domain graphic available
Description	Protein KIAA0859.

K1C14_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.004553 (rank : 169)
Query Neighborhood Hits	161	Target Neighborhood Hits	491	Shared Neighborhood Hits	17
SwissProt Accessions	P02533, Q14715, Q53XY3, Q9BUE3, Q9UBN2, Q9UBN3, Q9UCY4	Gene names	KRT14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

MBN3_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.009759 (rank : 150)
Query Neighborhood Hits	161	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUK0, Q5JXN8, Q5JXN9, Q5JXP4, Q6UDQ1, Q8TAD9, Q8TAF4, Q9H0Z7, Q9UF37	Gene names	MBNL3, CHCR, MBLX39, MBXL
Domain Architecture
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein HCHCR).

MPDZ_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.002587 (rank : 172)
Query Neighborhood Hits	161	Target Neighborhood Hits	261	Shared Neighborhood Hits	4
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MTMR9_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.005846 (rank : 164)
Query Neighborhood Hits	161	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2D0, Q80XL4	Gene names	Mtmr9, Mtmr3
Domain Architecture
Description	Myotubularin-related protein 9.

O5BF1_HUMAN
θ value	8.99809 (rank : 156)	NC score	-0.004585 (rank : 177)
Query Neighborhood Hits	161	Target Neighborhood Hits	699	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NHC7	Gene names	OR5BF1
Domain Architecture
Description	Olfactory receptor 5BF1.

P5CS_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.021351 (rank : 108)
Query Neighborhood Hits	161	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P54886, O95952, Q9UM72	Gene names	ALDH18A1, P5CS, PYCS
Domain Architecture
Description	Delta 1-pyrroline-5-carboxylate synthetase (P5CS) (Aldehyde dehydrogenase 18 family member A1) [Includes: Glutamate 5-kinase (EC 2.7.2.11) (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)].

RPGF2_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.005621 (rank : 165)
Query Neighborhood Hits	161	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

STX1A_HUMAN
θ value	8.99809 (rank : 159)	NC score	0.008460 (rank : 156)
Query Neighborhood Hits	161	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	Q16623, O15447, O15448, Q12936, Q9BPZ6	Gene names	STX1A, STX1
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

STX1A_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.008618 (rank : 155)
Query Neighborhood Hits	161	Target Neighborhood Hits	261	Shared Neighborhood Hits	10
SwissProt Accessions	O35526	Gene names	Stx1a
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

TACC3_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.011638 (rank : 145)
Query Neighborhood Hits	161	Target Neighborhood Hits	779	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

CAR12_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.146736 (rank : 73)
Query Neighborhood Hits	161	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

CGRF1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.058260 (rank : 81)
Query Neighborhood Hits	161	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CGRF1_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.056264 (rank : 82)
Query Neighborhood Hits	161	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

FTS1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.159868 (rank : 72)
Query Neighborhood Hits	161	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H8T0	Gene names	FTS
Domain Architecture	No domain graphic available
Description	Fused toes protein homolog (Ft1).

FTS1_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.162635 (rank : 71)
Query Neighborhood Hits	161	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q64362	Gene names	Fts, Fif, Ft1
Domain Architecture	No domain graphic available
Description	Fused toes protein (FT1).

MYLIP_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.061224 (rank : 80)
Query Neighborhood Hits	161	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

RFFL_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.084372 (rank : 78)
Query Neighborhood Hits	161	Target Neighborhood Hits	175	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.085913 (rank : 75)
Query Neighborhood Hits	161	Target Neighborhood Hits	145	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RKHD1_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.063328 (rank : 79)
Query Neighborhood Hits	161	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RNF26_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.094853 (rank : 74)
Query Neighborhood Hits	161	Target Neighborhood Hits	95	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RNF34_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.084419 (rank : 77)
Query Neighborhood Hits	161	Target Neighborhood Hits	153	Shared Neighborhood Hits	8
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.085521 (rank : 76)
Query Neighborhood Hits	161	Target Neighborhood Hits	160	Shared Neighborhood Hits	11
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

UB2V1_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.245509 (rank : 69)
Query Neighborhood Hits	161	Target Neighborhood Hits	53	Shared Neighborhood Hits	45
SwissProt Accessions	Q13404, Q13403, Q13532, Q96H34, Q9GZT0, Q9GZW1, Q9H4J3, Q9H4J4, Q9UKL1, Q9UM48, Q9UM49, Q9UM50	Gene names	UBE2V1, CROC1, UBE2V, UEV1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (Ubiquitin- conjugating enzyme variant Kua) (TRAF6-regulated IKK activator 1 beta Uev1A).

UB2V1_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.242782 (rank : 70)
Query Neighborhood Hits	161	Target Neighborhood Hits	49	Shared Neighborhood Hits	45
SwissProt Accessions	Q9CZY3, Q8VEB5, Q9ERI7	Gene names	Ube2v1, Croc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1).

UB2V2_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.251330 (rank : 68)
Query Neighborhood Hits	161	Target Neighborhood Hits	51	Shared Neighborhood Hits	45
SwissProt Accessions	Q15819	Gene names	UBE2V2, MMS2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 2 (MMS2) (Enterocyte differentiation-associated factor EDAF-1) (Enterocyte differentiation- promoting factor) (EDPF-1) (Vitamin D3-inducible protein) (DDVit 1).

UB2V2_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.254792 (rank : 67)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	47
SwissProt Accessions	Q9D2M8, Q8BGH6, Q8CE99, Q8K2V7, Q9CYD7, Q9ERI8	Gene names	Ube2v2, Mms2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 2 (Ubc-like protein MMS2).

Hits sorted by NC score

BIRC6_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

UB2G2_HUMAN
NC score	0.608468 (rank : 2)	θ value	1.25267e-09 (rank : 13)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P60604, P56554	Gene names	UBE2G2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G2 (EC 6.3.2.19) (Ubiquitin-protein ligase G2) (Ubiquitin carrier protein G2).

UB2G2_MOUSE
NC score	0.608468 (rank : 3)	θ value	1.25267e-09 (rank : 14)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P60605, P56554	Gene names	Ube2g2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G2 (EC 6.3.2.19) (Ubiquitin-protein ligase G2) (Ubiquitin carrier protein G2).

UBE2A_HUMAN
NC score	0.606817 (rank : 4)	θ value	4.59992e-12 (rank : 4)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P49459, Q4TTG1, Q96FX4	Gene names	UBE2A, RAD6A
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 A (EC 6.3.2.19) (Ubiquitin-protein ligase A) (Ubiquitin carrier protein A) (HR6A) (hHR6A).

UBE2A_MOUSE
NC score	0.606817 (rank : 5)	θ value	4.59992e-12 (rank : 5)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z255	Gene names	Ube2a, Rad6a
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 A (EC 6.3.2.19) (Ubiquitin-protein ligase A) (Ubiquitin carrier protein A) (HR6A) (mHR6A).

UBE2B_HUMAN
NC score	0.605314 (rank : 6)	θ value	1.74796e-11 (rank : 7)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P63146, P23567, Q4PJ15, Q9D0J6	Gene names	UBE2B, RAD6B
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 B (EC 6.3.2.19) (Ubiquitin-protein ligase B) (Ubiquitin carrier protein B) (HR6B) (hHR6B) (E2-17 kDa).

UBE2B_MOUSE
NC score	0.605314 (rank : 7)	θ value	1.74796e-11 (rank : 8)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P63147, P23567, Q3UGS2, Q9D0J6	Gene names	Ube2b, Rad6b
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 B (EC 6.3.2.19) (Ubiquitin-protein ligase B) (Ubiquitin carrier protein B) (HR6B) (E214K).

UBC9_HUMAN
NC score	0.601797 (rank : 8)	θ value	4.76016e-09 (rank : 22)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	P63279, P50550, Q15698, Q86VB3	Gene names	UBE2I, UBC9, UBCE9
Domain Architecture	No domain graphic available
Description	SUMO-1-conjugating enzyme UBC9 (EC 6.3.2.19) (SUMO-1-protein ligase) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (Ubiquitin carrier protein I) (Ubiquitin carrier protein 9) (p18).

UBC9_MOUSE
NC score	0.601797 (rank : 9)	θ value	4.76016e-09 (rank : 23)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	P63280, P50550, Q15698, Q86VB3	Gene names	Ube2i, Ubc9, Ubce9
Domain Architecture	No domain graphic available
Description	SUMO-1-conjugating enzyme UBC9 (EC 6.3.2.19) (SUMO-1-protein ligase) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (Ubiquitin carrier protein I) (Ubiquitin carrier protein 9) (mUBC9).

UB2R1_MOUSE
NC score	0.598701 (rank : 10)	θ value	2.13673e-09 (rank : 17)
Query Neighborhood Hits	161	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CFI2, Q505K8	Gene names	Cdc34
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-32 kDa complementing (EC 6.3.2.19) (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (E2-CDC34).

UB2R1_HUMAN
NC score	0.598606 (rank : 11)	θ value	2.13673e-09 (rank : 16)
Query Neighborhood Hits	161	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	P49427	Gene names	CDC34, UBE2R1
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-32 kDa complementing (EC 6.3.2.19) (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (E2-CDC34).

UB2G1_HUMAN
NC score	0.597347 (rank : 12)	θ value	2.79066e-09 (rank : 18)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P62253, Q99462	Gene names	UBE2G1, UBE2G
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G1 (EC 6.3.2.19) (Ubiquitin-protein ligase G1) (Ubiquitin carrier protein G1) (E217K) (UBC7).

UB2G1_MOUSE
NC score	0.597347 (rank : 13)	θ value	2.79066e-09 (rank : 19)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P62254, Q99462	Gene names	Ube2g1, Ube2g
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 G1 (EC 6.3.2.19) (Ubiquitin-protein ligase G1) (Ubiquitin carrier protein G1) (E217K) (UBC7).

UBE2T_HUMAN
NC score	0.596853 (rank : 14)	θ value	1.47974e-10 (rank : 10)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NPD8	Gene names	UBE2T
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 T (EC 6.3.2.19) (Ubiquitin-protein ligase T) (Ubiquitin carrier protein T).

UBE2N_HUMAN
NC score	0.594026 (rank : 15)	θ value	6.21693e-09 (rank : 24)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P61088, Q16781	Gene names	UBE2N, BLU
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 N (EC 6.3.2.19) (Ubiquitin-protein ligase N) (Ubiquitin carrier protein N) (Ubc13) (Bendless-like ubiquitin-conjugating enzyme).

UBE2N_MOUSE
NC score	0.594026 (rank : 16)	θ value	6.21693e-09 (rank : 25)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P61089, Q16781, Q6ZWZ0, Q9DAJ6	Gene names	Ube2n, Blu
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 N (EC 6.3.2.19) (Ubiquitin-protein ligase N) (Ubiquitin carrier protein N) (Ubc13) (Bendless-like ubiquitin-conjugating enzyme).

UBE2T_MOUSE
NC score	0.590668 (rank : 17)	θ value	3.64472e-09 (rank : 20)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CQ37	Gene names	Ube2t
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 T (EC 6.3.2.19) (Ubiquitin-protein ligase T) (Ubiquitin carrier protein T).

UBE2S_MOUSE
NC score	0.588078 (rank : 18)	θ value	1.53129e-07 (rank : 34)
Query Neighborhood Hits	161	Target Neighborhood Hits	54	Shared Neighborhood Hits	50
SwissProt Accessions	Q921J4, Q3U4V7	Gene names	Ube2s, E2epf
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 S (EC 6.3.2.19) (Ubiquitin-protein ligase S) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (E2-EPF5).

UBE2S_HUMAN
NC score	0.587950 (rank : 19)	θ value	1.53129e-07 (rank : 33)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q16763, Q9BTC1	Gene names	UBE2S, E2EPF
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 S (EC 6.3.2.19) (Ubiquitin-protein ligase S) (Ubiquitin carrier protein S) (Ubiquitin-conjugating enzyme E2-24 kDa) (E2-EPF5).

UB2L6_MOUSE
NC score	0.585967 (rank : 20)	θ value	6.87365e-08 (rank : 31)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QZU9, Q922F1, Q9CQN0	Gene names	Ube2l6, Ubce8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 L6 (EC 6.3.2.19) (Ubiquitin-protein ligase L6) (Ubiquitin carrier protein L6) (UbcM8).

UB2D2_HUMAN
NC score	0.575811 (rank : 21)	θ value	4.0297e-08 (rank : 27)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	P62837, P51669	Gene names	UBE2D2, UBC4, UBCH5B
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 D2 (EC 6.3.2.19) (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2).

UB2D2_MOUSE
NC score	0.575811 (rank : 22)	θ value	4.0297e-08 (rank : 28)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	P62838, P51669	Gene names	Ube2d2, Ubc4
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 D2 (EC 6.3.2.19) (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2).

UB2D3_HUMAN
NC score	0.575688 (rank : 23)	θ value	4.0297e-08 (rank : 29)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	P61077, P47986, Q6IB88, Q6NXS4	Gene names	UBE2D3, UBCH5C
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D3 (EC 6.3.2.19) (Ubiquitin-protein ligase D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (E2(17)KB 3).

UB2D3_MOUSE
NC score	0.575688 (rank : 24)	θ value	4.0297e-08 (rank : 30)
Query Neighborhood Hits	161	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	P61079	Gene names	Ube2d3
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D3 (EC 6.3.2.19) (Ubiquitin-protein ligase D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (E2(17)KB 3).

UB2L3_HUMAN
NC score	0.575233 (rank : 25)	θ value	6.43352e-06 (rank : 43)
Query Neighborhood Hits	161	Target Neighborhood Hits	63	Shared Neighborhood Hits	50
SwissProt Accessions	P68036, P51966, P70653, Q9HAV1	Gene names	UBE2L3, UBCE7, UBCH7
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcH7) (E2-F1) (L-UBC).

UB2L3_MOUSE
NC score	0.575233 (rank : 26)	θ value	6.43352e-06 (rank : 44)
Query Neighborhood Hits	161	Target Neighborhood Hits	63	Shared Neighborhood Hits	50
SwissProt Accessions	P68037, P51966, P70653, Q9HAV1	Gene names	Ube2l3, Ubce7
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcM4).

UB2D1_HUMAN
NC score	0.572369 (rank : 27)	θ value	3.41135e-07 (rank : 35)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P51668	Gene names	UBE2D1, UBCH5, UBCH5A
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D1 (EC 6.3.2.19) (Ubiquitin-protein ligase D1) (Ubiquitin carrier protein D1) (UbcH5) (Ubiquitin- conjugating enzyme E2-17 kDa 1) (E2(17)KB 1).

UB2D1_MOUSE
NC score	0.572369 (rank : 28)	θ value	3.41135e-07 (rank : 36)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P61080	Gene names	Ube2d1
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 D1 (EC 6.3.2.19) (Ubiquitin-protein ligase D1) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (E2(17)KB 1).

UB2L6_HUMAN
NC score	0.569208 (rank : 29)	θ value	2.44474e-05 (rank : 46)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	O14933, Q9UEZ0	Gene names	UBE2L6, UBCH8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 L6 (EC 6.3.2.19) (Ubiquitin-protein ligase L6) (Ubiquitin carrier protein L6) (UbcH8) (Retinoic acid- induced gene B protein) (RIG-B).

UBE2C_HUMAN
NC score	0.568887 (rank : 30)	θ value	1.43324e-05 (rank : 45)
Query Neighborhood Hits	161	Target Neighborhood Hits	54	Shared Neighborhood Hits	50
SwissProt Accessions	O00762	Gene names	UBE2C, UBCH10
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 C (EC 6.3.2.19) (Ubiquitin-protein ligase C) (Ubiquitin carrier protein C) (UbcH10).

UBE2C_MOUSE
NC score	0.564860 (rank : 31)	θ value	9.29e-05 (rank : 53)
Query Neighborhood Hits	161	Target Neighborhood Hits	54	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D1C1, Q3TUJ0	Gene names	Ube2c, Ubch10
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 C (EC 6.3.2.19) (Ubiquitin-protein ligase C) (Ubiquitin carrier protein C) (UbcH10).

UBC1_HUMAN
NC score	0.554990 (rank : 32)	θ value	5.44631e-05 (rank : 51)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	50
SwissProt Accessions	P61086, O54806, P27924, Q16721, Q9CVV9, Q9Y2D3	Gene names	HIP2, LIG
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-25 kDa (EC 6.3.2.19) (Ubiquitin- protein ligase) (Ubiquitin carrier protein) (E2(25K)) (Huntingtin- interacting protein 2) (HIP-2).

UBC1_MOUSE
NC score	0.554990 (rank : 33)	θ value	5.44631e-05 (rank : 52)
Query Neighborhood Hits	161	Target Neighborhood Hits	65	Shared Neighborhood Hits	50
SwissProt Accessions	P61087, O54806, P27924, Q16721, Q9CVV9	Gene names	Hip2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2-25 kDa (EC 6.3.2.19) (Ubiquitin- protein ligase) (Ubiquitin carrier protein) (E2(25K)) (Huntingtin- interacting protein 2) (HIP-2).

UB2E3_HUMAN
NC score	0.551164 (rank : 34)	θ value	3.19293e-05 (rank : 47)
Query Neighborhood Hits	161	Target Neighborhood Hits	62	Shared Neighborhood Hits	50
SwissProt Accessions	Q969T4, Q5U0R7, Q7Z4W4	Gene names	UBE2E3, UBCE4, UBCH9
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E3 (EC 6.3.2.19) (Ubiquitin-protein ligase E3) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (UbcH9) (UbcM2).

UB2E3_MOUSE
NC score	0.551164 (rank : 35)	θ value	3.19293e-05 (rank : 48)
Query Neighborhood Hits	161	Target Neighborhood Hits	62	Shared Neighborhood Hits	50
SwissProt Accessions	P52483, O09180, Q3TI00, Q91X63	Gene names	Ube2e3, Ubce4, Ubcm2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E3 (EC 6.3.2.19) (Ubiquitin-protein ligase E3) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (UbcM2).

UB2E2_HUMAN
NC score	0.549768 (rank : 36)	θ value	4.1701e-05 (rank : 49)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q96LR5	Gene names	UBE2E2, UBCH8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2) (UbcH8).

UB2E2_MOUSE
NC score	0.548978 (rank : 37)	θ value	4.1701e-05 (rank : 50)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q91W82	Gene names	Ube2e2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2).

UB2E1_HUMAN
NC score	0.547314 (rank : 38)	θ value	0.000121331 (rank : 54)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	P51965	Gene names	UBE2E1, UBCH6
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E1 (EC 6.3.2.19) (Ubiquitin-protein ligase E1) (Ubiquitin carrier protein E1) (UbcH6).

UB2E1_MOUSE
NC score	0.545927 (rank : 39)	θ value	0.000121331 (rank : 55)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P52482	Gene names	Ube2e1, Ubce5, Ubcm3
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E1 (EC 6.3.2.19) (Ubiquitin-protein ligase E1) (Ubiquitin carrier protein E1) (UbcM3).

UBC12_HUMAN
NC score	0.542311 (rank : 40)	θ value	0.000786445 (rank : 56)
Query Neighborhood Hits	161	Target Neighborhood Hits	48	Shared Neighborhood Hits	46
SwissProt Accessions	P61081, O76069, Q8VC50	Gene names	UBE2M, UBC12
Domain Architecture
Description	NEDD8-conjugating enzyme Ubc12 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme E2 M) (NEDD8 protein ligase) (NEDD8 carrier protein).

UBC12_MOUSE
NC score	0.542311 (rank : 41)	θ value	0.000786445 (rank : 57)
Query Neighborhood Hits	161	Target Neighborhood Hits	48	Shared Neighborhood Hits	46
SwissProt Accessions	P61082, O76069, Q8VC50	Gene names	Ube2m, Ubc-rs2, Ubc12
Domain Architecture
Description	NEDD8-conjugating enzyme Ubc12 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme E2 M) (NEDD8 protein ligase) (NEDD8 carrier protein).

UBE2H_HUMAN
NC score	0.533438 (rank : 42)	θ value	0.0563607 (rank : 63)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P62256, P37286	Gene names	UBE2H
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) (Ubiquitin-protein ligase H) (Ubiquitin carrier protein H) (UbcH2) (E2-20K).

UBE2H_MOUSE
NC score	0.533438 (rank : 43)	θ value	0.0563607 (rank : 64)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	50
SwissProt Accessions	P62257, P37286	Gene names	Ube2h
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) (Ubiquitin-protein ligase H) (Ubiquitin carrier protein H) (UBCH2) (E2-20K).

UBE2U_HUMAN
NC score	0.515188 (rank : 44)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q5VVX9, Q8N1D4	Gene names	UBE2U
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 U (EC 6.3.2.19) (Ubiquitin-protein ligase U) (Ubiquitin carrier protein U).

UBE2W_MOUSE
NC score	0.511142 (rank : 45)	θ value	0.0736092 (rank : 65)
Query Neighborhood Hits	161	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VDW4, Q9D5H3	Gene names	Ube2w
Domain Architecture	No domain graphic available
Description	Probable ubiquitin-conjugating enzyme E2 W (EC 6.3.2.19) (Ubiquitin- protein ligase W) (Ubiquitin carrier protein W).

UBE2W_HUMAN
NC score	0.509921 (rank : 46)	θ value	0.0961366 (rank : 66)
Query Neighborhood Hits	161	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q96B02, Q9H823, Q9HAG6, Q9NV07	Gene names	UBE2W
Domain Architecture	No domain graphic available
Description	Probable ubiquitin-conjugating enzyme E2 W (EC 6.3.2.19) (Ubiquitin- protein ligase W) (Ubiquitin carrier protein W).

UB2J2_MOUSE
NC score	0.488205 (rank : 47)	θ value	0.00298849 (rank : 59)
Query Neighborhood Hits	161	Target Neighborhood Hits	55	Shared Neighborhood Hits	48
SwissProt Accessions	Q6P073, Q8C6A1, Q91Y64, Q9CWY5, Q9DC18, Q9QX58	Gene names	Ube2j2, Ncube2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J2 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE2).

UB2J2_HUMAN
NC score	0.486000 (rank : 48)	θ value	0.00298849 (rank : 58)
Query Neighborhood Hits	161	Target Neighborhood Hits	54	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N2K1, Q96N26, Q96T84	Gene names	UBE2J2, NCUBE2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J2 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE2).

BIRC5_MOUSE
NC score	0.478743 (rank : 49)	θ value	1.33837e-11 (rank : 6)
Query Neighborhood Hits	161	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

BIRC5_HUMAN
NC score	0.473040 (rank : 50)	θ value	8.67504e-11 (rank : 9)
Query Neighborhood Hits	161	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

UB2J1_HUMAN
NC score	0.451044 (rank : 51)	θ value	0.0113563 (rank : 60)
Query Neighborhood Hits	161	Target Neighborhood Hits	61	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y385, Q5W0N4, Q9BZ32, Q9NQL3, Q9NY66, Q9P011, Q9P0S0, Q9UF10	Gene names	UBE2J1, NCUBE1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HSUBC6e).

UB2J1_MOUSE
NC score	0.450171 (rank : 52)	θ value	0.0113563 (rank : 61)
Query Neighborhood Hits	161	Target Neighborhood Hits	74	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JJZ4, Q9DC92	Gene names	Ube2j1, Ncube1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1).

BIRC4_HUMAN
NC score	0.410027 (rank : 53)	θ value	2.0648e-12 (rank : 2)
Query Neighborhood Hits	161	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC4_MOUSE
NC score	0.409424 (rank : 54)	θ value	4.59992e-12 (rank : 3)
Query Neighborhood Hits	161	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BIRC3_HUMAN
NC score	0.380896 (rank : 55)	θ value	9.59137e-10 (rank : 12)
Query Neighborhood Hits	161	Target Neighborhood Hits	133	Shared Neighborhood Hits	17
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC2_HUMAN
NC score	0.380637 (rank : 56)	θ value	9.59137e-10 (rank : 11)
Query Neighborhood Hits	161	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
NC score	0.379131 (rank : 57)	θ value	1.63604e-09 (rank : 15)
Query Neighborhood Hits	161	Target Neighborhood Hits	137	Shared Neighborhood Hits	17
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_MOUSE
NC score	0.378831 (rank : 58)	θ value	4.76016e-09 (rank : 21)
Query Neighborhood Hits	161	Target Neighborhood Hits	113	Shared Neighborhood Hits	18
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC8_HUMAN
NC score	0.371664 (rank : 59)	θ value	6.43352e-06 (rank : 42)
Query Neighborhood Hits	161	Target Neighborhood Hits	121	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BIRC7_HUMAN
NC score	0.354464 (rank : 60)	θ value	1.53129e-07 (rank : 32)
Query Neighborhood Hits	161	Target Neighborhood Hits	185	Shared Neighborhood Hits	18
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BIR1B_MOUSE
NC score	0.332930 (rank : 61)	θ value	4.0297e-08 (rank : 26)
Query Neighborhood Hits	161	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIRC1_HUMAN
NC score	0.331518 (rank : 62)	θ value	7.59969e-07 (rank : 37)
Query Neighborhood Hits	161	Target Neighborhood Hits	61	Shared Neighborhood Hits	18
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1E_MOUSE
NC score	0.325691 (rank : 63)	θ value	2.88788e-06 (rank : 40)
Query Neighborhood Hits	161	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
NC score	0.325611 (rank : 64)	θ value	2.21117e-06 (rank : 38)
Query Neighborhood Hits	161	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
NC score	0.325202 (rank : 65)	θ value	2.88788e-06 (rank : 41)
Query Neighborhood Hits	161	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIR1A_MOUSE
NC score	0.324270 (rank : 66)	θ value	2.88788e-06 (rank : 39)
Query Neighborhood Hits	161	Target Neighborhood Hits	94	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

UB2V2_MOUSE
NC score	0.254792 (rank : 67)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	161	Target Neighborhood Hits	52	Shared Neighborhood Hits	47
SwissProt Accessions	Q9D2M8, Q8BGH6, Q8CE99, Q8K2V7, Q9CYD7, Q9ERI8	Gene names	Ube2v2, Mms2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 2 (Ubc-like protein MMS2).

UB2V2_HUMAN
NC score	0.251330 (rank : 68)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	161	Target Neighborhood Hits	51	Shared Neighborhood Hits	45
SwissProt Accessions	Q15819	Gene names	UBE2V2, MMS2
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 2 (MMS2) (Enterocyte differentiation-associated factor EDAF-1) (Enterocyte differentiation- promoting factor) (EDPF-1) (Vitamin D3-inducible protein) (DDVit 1).

UB2V1_HUMAN
NC score	0.245509 (rank : 69)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	161	Target Neighborhood Hits	53	Shared Neighborhood Hits	45
SwissProt Accessions	Q13404, Q13403, Q13532, Q96H34, Q9GZT0, Q9GZW1, Q9H4J3, Q9H4J4, Q9UKL1, Q9UM48, Q9UM49, Q9UM50	Gene names	UBE2V1, CROC1, UBE2V, UEV1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (Ubiquitin- conjugating enzyme variant Kua) (TRAF6-regulated IKK activator 1 beta Uev1A).

UB2V1_MOUSE
NC score	0.242782 (rank : 70)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	161	Target Neighborhood Hits	49	Shared Neighborhood Hits	45
SwissProt Accessions	Q9CZY3, Q8VEB5, Q9ERI7	Gene names	Ube2v1, Croc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1).

FTS1_MOUSE
NC score	0.162635 (rank : 71)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	161	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q64362	Gene names	Fts, Fif, Ft1
Domain Architecture	No domain graphic available
Description	Fused toes protein (FT1).

FTS1_HUMAN
NC score	0.159868 (rank : 72)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	161	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H8T0	Gene names	FTS
Domain Architecture	No domain graphic available
Description	Fused toes protein homolog (Ft1).

CAR12_HUMAN
NC score	0.146736 (rank : 73)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	161	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

RNF26_HUMAN
NC score	0.094853 (rank : 74)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	161	Target Neighborhood Hits	95	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RFFL_MOUSE
NC score	0.085913 (rank : 75)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	161	Target Neighborhood Hits	145	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RNF34_MOUSE
NC score	0.085521 (rank : 76)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	161	Target Neighborhood Hits	160	Shared Neighborhood Hits	11
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF34_HUMAN
NC score	0.084419 (rank : 77)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	161	Target Neighborhood Hits	153	Shared Neighborhood Hits	8
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RFFL_HUMAN
NC score	0.084372 (rank : 78)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	161	Target Neighborhood Hits	175	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RKHD1_HUMAN
NC score	0.063328 (rank : 79)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	161	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

MYLIP_HUMAN
NC score	0.061224 (rank : 80)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	161	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

CGRF1_HUMAN
NC score	0.058260 (rank : 81)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	161	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CGRF1_MOUSE
NC score	0.056264 (rank : 82)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	161	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

SCFD2_MOUSE
NC score	0.039910 (rank : 83)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	161	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BTY8, Q3USN5, Q8BFV9, Q8BKU5, Q8BKZ0, Q8BTP6, Q8BTQ9, Q8BXI1, Q8BXS0, Q8BZ58	Gene names	Scfd2, Stxbp1l1
Domain Architecture	No domain graphic available
Description	Sec1 family domain-containing protein 2 (Syntaxin-binding protein 1- like 1) (Neuronal Sec1).

TS101_HUMAN
NC score	0.039858 (rank : 84)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	161	Target Neighborhood Hits	359	Shared Neighborhood Hits	12
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

USP9Y_HUMAN
NC score	0.039410 (rank : 85)	θ value	0.0961366 (rank : 67)
Query Neighborhood Hits	161	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

CLN3_HUMAN
NC score	0.038358 (rank : 86)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	161	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q13286, O00668, Q9UP09, Q9UP11, Q9UP12, Q9UP13, Q9UP14	Gene names	CLN3, BTS
Domain Architecture
Description	Protein CLN3 (Battenin) (Batten disease protein).

WDR75_HUMAN
NC score	0.036436 (rank : 87)	θ value	0.813845 (rank : 81)
Query Neighborhood Hits	161	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWA0, Q96J10, Q9H8U8, Q9H9U5, Q9H9V8, Q9UIX2	Gene names	WDR75
Domain Architecture	No domain graphic available
Description	WD repeat protein 75.

FEZ2_HUMAN
NC score	0.035797 (rank : 88)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	161	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHY8, Q76LN0, Q99690	Gene names	FEZ2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

ARRS_MOUSE
NC score	0.034500 (rank : 89)	θ value	0.279714 (rank : 68)
Query Neighborhood Hits	161	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P20443, Q91W62	Gene names	Sag
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

IFT74_HUMAN
NC score	0.032802 (rank : 90)	θ value	0.0431538 (rank : 62)
Query Neighborhood Hits	161	Target Neighborhood Hits	949	Shared Neighborhood Hits	28
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

LRRF1_HUMAN
NC score	0.031924 (rank : 91)	θ value	0.47712 (rank : 72)
Query Neighborhood Hits	161	Target Neighborhood Hits	625	Shared Neighborhood Hits	15
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

USP9X_MOUSE
NC score	0.031155 (rank : 92)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	161	Target Neighborhood Hits	171	Shared Neighborhood Hits	5
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9X_HUMAN
NC score	0.031056 (rank : 93)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

TS101_MOUSE
NC score	0.031009 (rank : 94)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	161	Target Neighborhood Hits	312	Shared Neighborhood Hits	11
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

K0423_HUMAN
NC score	0.028832 (rank : 95)	θ value	1.06291 (rank : 84)
Query Neighborhood Hits	161	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

P5CS_MOUSE
NC score	0.027896 (rank : 96)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	161	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z110, Q9R1P6	Gene names	Aldh18a1, P5cs, Pycs
Domain Architecture
Description	Delta 1-pyrroline-5-carboxylate synthetase (P5CS) (Aldehyde dehydrogenase 18 family member A1) [Includes: Glutamate 5-kinase (EC 2.7.2.11) (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)].

CLSPN_MOUSE
NC score	0.026876 (rank : 97)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	161	Target Neighborhood Hits	292	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

IFT74_MOUSE
NC score	0.025839 (rank : 98)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	161	Target Neighborhood Hits	939	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

TM108_HUMAN
NC score	0.025073 (rank : 99)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	161	Target Neighborhood Hits	166	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

PLCB1_MOUSE
NC score	0.024984 (rank : 100)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	161	Target Neighborhood Hits	531	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

ARRS_HUMAN
NC score	0.023851 (rank : 101)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	161	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P10523, Q53SV3, Q99858	Gene names	SAG
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

PLCB1_HUMAN
NC score	0.023766 (rank : 102)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	161	Target Neighborhood Hits	614	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

P3H3_HUMAN
NC score	0.023744 (rank : 103)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	161	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IVL6, Q13512, Q15740, Q66K32, Q6NX61, Q7L2T1	Gene names	LEPREL2, P3H3
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 3 precursor (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B).

CCD62_HUMAN
NC score	0.023229 (rank : 104)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	161	Target Neighborhood Hits	631	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

LRC45_HUMAN
NC score	0.022449 (rank : 105)	θ value	0.365318 (rank : 70)
Query Neighborhood Hits	161	Target Neighborhood Hits	933	Shared Neighborhood Hits	23
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

DYH5_MOUSE
NC score	0.021898 (rank : 106)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	161	Target Neighborhood Hits	286	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

HPS5_HUMAN
NC score	0.021531 (rank : 107)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	161	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPZ3, O95942, Q8N4U0	Gene names	HPS5, AIBP63, KIAA1017
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein (Alpha-integrin-binding protein 63) (Ruby-eye protein 2 homolog) (Ru2).

P5CS_HUMAN
NC score	0.021351 (rank : 108)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	161	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P54886, O95952, Q9UM72	Gene names	ALDH18A1, P5CS, PYCS
Domain Architecture
Description	Delta 1-pyrroline-5-carboxylate synthetase (P5CS) (Aldehyde dehydrogenase 18 family member A1) [Includes: Glutamate 5-kinase (EC 2.7.2.11) (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)].

BCL9_HUMAN
NC score	0.020920 (rank : 109)	θ value	0.365318 (rank : 69)
Query Neighborhood Hits	161	Target Neighborhood Hits	1008	Shared Neighborhood Hits	8
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MBD5_HUMAN
NC score	0.020878 (rank : 110)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	161	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

S35B2_HUMAN
NC score	0.019651 (rank : 111)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	161	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TB61, Q5T9W1, Q5T9W2, Q7Z2G3, Q8NBK6, Q96AR6	Gene names	SLC35B2, PAPST1
Domain Architecture	No domain graphic available
Description	Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (PAPS transporter 1) (Solute carrier family 35 member B2) (Putative MAPK-activating protein PM15) (Putative NF-kappa-B-activating protein 48).

CT026_HUMAN
NC score	0.019332 (rank : 112)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	161	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHU2, Q5TE18, Q8N5R9, Q96M59, Q9BQL2, Q9H127, Q9H128, Q9NQH4, Q9UFV8, Q9Y4V7	Gene names	C20orf26
Domain Architecture
Description	Uncharacterized protein C20orf26.

PK3CB_HUMAN
NC score	0.019056 (rank : 113)	θ value	1.06291 (rank : 86)
Query Neighborhood Hits	161	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

CCM2_MOUSE
NC score	0.018957 (rank : 114)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	161	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2Y9	Gene names	Ccm2, Osm
Domain Architecture	No domain graphic available
Description	Malcavernin (Cerebral cavernous malformations protein 2 homolog) (Osmosensing scaffold for MEKK3).

CI093_HUMAN
NC score	0.018753 (rank : 115)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	161	Target Neighborhood Hits	1088	Shared Neighborhood Hits	25
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

RABE1_MOUSE
NC score	0.017896 (rank : 116)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	161	Target Neighborhood Hits	1105	Shared Neighborhood Hits	27
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RCOR1_HUMAN
NC score	0.017623 (rank : 117)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	161	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKL0, Q15044, Q6P2I9, Q86VG5	Gene names	RCOR1, KIAA0071, RCOR
Domain Architecture	No domain graphic available
Description	REST corepressor 1 (Protein CoREST).

RCOR1_MOUSE
NC score	0.017437 (rank : 118)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	161	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CFE3, Q3V092, Q8BK28, Q8CHI2	Gene names	Rcor1, D12Wsu95e, Kiaa0071
Domain Architecture	No domain graphic available
Description	REST corepressor 1 (Protein CoREST).

SFRP5_HUMAN
NC score	0.017273 (rank : 119)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	161	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

CCM2_HUMAN
NC score	0.017187 (rank : 120)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	161	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSQ5, Q71RE5, Q8TAT4	Gene names	CCM2, C7orf22
Domain Architecture	No domain graphic available
Description	Malcavernin (Cerebral cavernous malformations 2 protein).

PXDC1_MOUSE
NC score	0.016641 (rank : 121)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	161	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q91ZV7, Q8BM20, Q9CWV5	Gene names	Plxdc1, Tem7
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 1 precursor (Tumor endothelial marker 7).

FOXP4_HUMAN
NC score	0.016191 (rank : 122)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	161	Target Neighborhood Hits	246	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

FA45B_HUMAN
NC score	0.016190 (rank : 123)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	161	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NSW5, Q9NZ36	Gene names	FAM45B
Domain Architecture	No domain graphic available
Description	Protein FAM45B.

BPAEA_HUMAN
NC score	0.016062 (rank : 124)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	161	Target Neighborhood Hits	1369	Shared Neighborhood Hits	30
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PTRF_MOUSE
NC score	0.016049 (rank : 125)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	161	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	O54724	Gene names	Ptrf
Domain Architecture	No domain graphic available
Description	Polymerase I and transcript release factor.

TRAIP_HUMAN
NC score	0.015653 (rank : 126)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	161	Target Neighborhood Hits	780	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

RABE1_HUMAN
NC score	0.015642 (rank : 127)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	161	Target Neighborhood Hits	1104	Shared Neighborhood Hits	27
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

PK3CB_MOUSE
NC score	0.015391 (rank : 128)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	161	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

CN037_MOUSE
NC score	0.014961 (rank : 129)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	161	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

FAS_MOUSE
NC score	0.014881 (rank : 130)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	161	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P19096, Q6PB72, Q8C4Z0, Q9EQR0	Gene names	Fasn
Domain Architecture	No domain graphic available
Description	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S- acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S- malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.10); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)].

GOGA3_MOUSE
NC score	0.014666 (rank : 131)	θ value	1.06291 (rank : 83)
Query Neighborhood Hits	161	Target Neighborhood Hits	1437	Shared Neighborhood Hits	33
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

ANR18_HUMAN
NC score	0.014644 (rank : 132)	θ value	0.813845 (rank : 78)
Query Neighborhood Hits	161	Target Neighborhood Hits	1106	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

SFRP1_HUMAN
NC score	0.014486 (rank : 133)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	161	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

SFRP5_MOUSE
NC score	0.014161 (rank : 134)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	161	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

SPTN5_HUMAN
NC score	0.013786 (rank : 135)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	161	Target Neighborhood Hits	674	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

PKHA6_MOUSE
NC score	0.013580 (rank : 136)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	161	Target Neighborhood Hits	591	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

BCL7C_MOUSE
NC score	0.013572 (rank : 137)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	161	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

CRGB_HUMAN
NC score	0.013300 (rank : 138)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	161	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P07316	Gene names	CRYGB, CRYG2
Domain Architecture
Description	Gamma crystallin B (Gamma crystallin 1-2).

TNR1B_MOUSE
NC score	0.013041 (rank : 139)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	161	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

VWF_MOUSE
NC score	0.012966 (rank : 140)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	161	Target Neighborhood Hits	381	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MLH1_MOUSE
NC score	0.012835 (rank : 141)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	161	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JK91, Q62454	Gene names	Mlh1
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

K0859_HUMAN
NC score	0.012169 (rank : 142)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	161	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N6R0, O94940, Q5TGP9, Q5TGQ0, Q8N2P8, Q96J11, Q96SQ0, Q9Y2Z1, Q9Y3M6	Gene names	KIAA0859
Domain Architecture	No domain graphic available
Description	Protein KIAA0859.

CEP63_HUMAN
NC score	0.012114 (rank : 143)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	161	Target Neighborhood Hits	1005	Shared Neighborhood Hits	25
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

LARGE_MOUSE
NC score	0.011970 (rank : 144)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	161	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1M7, Q497S9, Q6P7U2, Q80TW0	Gene names	Large, Kiaa0609, Large1
Domain Architecture
Description	Glycosyltransferase-like protein LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A).

TACC3_HUMAN
NC score	0.011638 (rank : 145)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	161	Target Neighborhood Hits	779	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

CT2NL_HUMAN
NC score	0.011526 (rank : 146)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	161	Target Neighborhood Hits	1059	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

PKD1_HUMAN
NC score	0.011053 (rank : 147)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	161	Target Neighborhood Hits	387	Shared Neighborhood Hits	3
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

ANR38_MOUSE
NC score	0.011000 (rank : 148)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	161	Target Neighborhood Hits	512	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

GAS8_HUMAN
NC score	0.010888 (rank : 149)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	161	Target Neighborhood Hits	819	Shared Neighborhood Hits	20
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

MBN3_HUMAN
NC score	0.009759 (rank : 150)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	161	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUK0, Q5JXN8, Q5JXN9, Q5JXP4, Q6UDQ1, Q8TAD9, Q8TAF4, Q9H0Z7, Q9UF37	Gene names	MBNL3, CHCR, MBLX39, MBXL
Domain Architecture
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein HCHCR).

MYH11_HUMAN
NC score	0.009670 (rank : 151)	θ value	1.06291 (rank : 85)
Query Neighborhood Hits	161	Target Neighborhood Hits	1806	Shared Neighborhood Hits	34
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PAR14_MOUSE
NC score	0.009421 (rank : 152)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	161	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

IF122_HUMAN
NC score	0.009114 (rank : 153)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	161	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBG6	Gene names	IFT122, WDR10, WDR140
Domain Architecture
Description	Intraflagellar transport 122 homolog (WD repeat protein 10).

DNAI2_HUMAN
NC score	0.009060 (rank : 154)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	161	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZS0, Q9H179, Q9NT53	Gene names	DNAI2
Domain Architecture
Description	Dynein intermediate chain 2, axonemal (Axonemal dynein intermediate chain 2).

STX1A_MOUSE
NC score	0.008618 (rank : 155)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	161	Target Neighborhood Hits	261	Shared Neighborhood Hits	10
SwissProt Accessions	O35526	Gene names	Stx1a
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

STX1A_HUMAN
NC score	0.008460 (rank : 156)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	161	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	Q16623, O15447, O15448, Q12936, Q9BPZ6	Gene names	STX1A, STX1
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

TBD_HUMAN
NC score	0.008308 (rank : 157)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	161	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJT1, Q9BWG9, Q9H7Z8	Gene names	TUBD1, TUBD
Domain Architecture
Description	Tubulin delta chain (Delta tubulin).

ANR15_HUMAN
NC score	0.007646 (rank : 158)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	161	Target Neighborhood Hits	478	Shared Neighborhood Hits	12
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

WD51B_MOUSE
NC score	0.007186 (rank : 159)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	161	Target Neighborhood Hits	321	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHD1	Gene names	Wdr51b
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

BRCA1_HUMAN
NC score	0.006693 (rank : 160)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	161	Target Neighborhood Hits	381	Shared Neighborhood Hits	4
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

WD51B_HUMAN
NC score	0.006631 (rank : 161)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	161	Target Neighborhood Hits	335	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

LRC19_HUMAN
NC score	0.006561 (rank : 162)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	161	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H756	Gene names	LRRC19
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 19 precursor.

K1C14_MOUSE
NC score	0.006409 (rank : 163)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	161	Target Neighborhood Hits	501	Shared Neighborhood Hits	19
SwissProt Accessions	Q61781, Q91VQ4	Gene names	Krt14, Krt1-14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

MTMR9_MOUSE
NC score	0.005846 (rank : 164)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	161	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2D0, Q80XL4	Gene names	Mtmr9, Mtmr3
Domain Architecture
Description	Myotubularin-related protein 9.

RPGF2_HUMAN
NC score	0.005621 (rank : 165)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	161	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

GP176_MOUSE
NC score	0.005556 (rank : 166)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	161	Target Neighborhood Hits	539	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

BRD3_HUMAN
NC score	0.005543 (rank : 167)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	161	Target Neighborhood Hits	369	Shared Neighborhood Hits	8
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

ABCAD_MOUSE
NC score	0.005167 (rank : 168)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	161	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

K1C14_HUMAN
NC score	0.004553 (rank : 169)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	161	Target Neighborhood Hits	491	Shared Neighborhood Hits	17
SwissProt Accessions	P02533, Q14715, Q53XY3, Q9BUE3, Q9UBN2, Q9UBN3, Q9UCY4	Gene names	KRT14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

CAC1I_HUMAN
NC score	0.003399 (rank : 170)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	161	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

PO6F1_MOUSE
NC score	0.002710 (rank : 171)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	161	Target Neighborhood Hits	581	Shared Neighborhood Hits	5
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

MPDZ_HUMAN
NC score	0.002587 (rank : 172)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	161	Target Neighborhood Hits	261	Shared Neighborhood Hits	4
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

EMR1_MOUSE
NC score	0.000772 (rank : 173)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	161	Target Neighborhood Hits	349	Shared Neighborhood Hits	3
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR1_HUMAN
NC score	0.000743 (rank : 174)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	161	Target Neighborhood Hits	382	Shared Neighborhood Hits	3
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

OX1R_HUMAN
NC score	-0.000020 (rank : 175)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	161	Target Neighborhood Hits	909	Shared Neighborhood Hits	4
SwissProt Accessions	O43613	Gene names	HCRTR1
Domain Architecture
Description	Orexin receptor type 1 (Ox1r) (Hypocretin receptor type 1).

GAK_HUMAN
NC score	-0.002963 (rank : 176)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	161	Target Neighborhood Hits	1028	Shared Neighborhood Hits	3
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

O5BF1_HUMAN
NC score	-0.004585 (rank : 177)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	161	Target Neighborhood Hits	699	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NHC7	Gene names	OR5BF1
Domain Architecture
Description	Olfactory receptor 5BF1.