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Network neighborhood for query Sequence : PAR14_MOUSE

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PAR14_MOUSE
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PAR14_HUMAN
θ value	0 (rank : 1)	NC score	0.983019 (rank : 2)
Query Neighborhood Hits	113	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

PAR14_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	113
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PAR15_HUMAN
θ value	8.73085e-104 (rank : 3)	NC score	0.925679 (rank : 3)
Query Neighborhood Hits	113	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q460N3, Q8N1K3	Gene names	PARP15, BAL3
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 15 (EC 2.4.2.30) (PARP-15) (B-aggressive lymphoma protein 3).

PARP9_MOUSE
θ value	1.36585e-56 (rank : 4)	NC score	0.807987 (rank : 5)
Query Neighborhood Hits	113	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CAS9, Q99LF9	Gene names	Parp9, Bal
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein homolog).

PARP9_HUMAN
θ value	7.75577e-52 (rank : 5)	NC score	0.810188 (rank : 4)
Query Neighborhood Hits	113	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

PAR10_HUMAN
θ value	4.72714e-33 (rank : 6)	NC score	0.679239 (rank : 10)
Query Neighborhood Hits	113	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

PAR12_MOUSE
θ value	8.91499e-32 (rank : 7)	NC score	0.689306 (rank : 8)
Query Neighborhood Hits	113	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PAR12_HUMAN
θ value	1.98606e-31 (rank : 8)	NC score	0.685490 (rank : 9)
Query Neighborhood Hits	113	Target Neighborhood Hits	42	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PARPT_HUMAN
θ value	6.38894e-30 (rank : 9)	NC score	0.699559 (rank : 7)
Query Neighborhood Hits	113	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

PARPT_MOUSE
θ value	6.38894e-30 (rank : 10)	NC score	0.699786 (rank : 6)
Query Neighborhood Hits	113	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

ZCC2_HUMAN
θ value	6.62687e-19 (rank : 11)	NC score	0.641376 (rank : 11)
Query Neighborhood Hits	113	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

LRP16_HUMAN
θ value	9.56915e-18 (rank : 12)	NC score	0.546403 (rank : 12)
Query Neighborhood Hits	113	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BQ69, Q9UH96	Gene names	LRP16
Domain Architecture
Description	Protein LRP16.

LRP16_MOUSE
θ value	2.60593e-15 (rank : 13)	NC score	0.534480 (rank : 13)
Query Neighborhood Hits	113	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q922B1	Gene names	Lrp16
Domain Architecture
Description	Protein LRP16.

H2AY_HUMAN
θ value	3.76295e-14 (rank : 14)	NC score	0.296154 (rank : 14)
Query Neighborhood Hits	113	Target Neighborhood Hits	48	Shared Neighborhood Hits	11
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

H2AY_MOUSE
θ value	4.91457e-14 (rank : 15)	NC score	0.295573 (rank : 15)
Query Neighborhood Hits	113	Target Neighborhood Hits	49	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

H2AW_HUMAN
θ value	8.67504e-11 (rank : 16)	NC score	0.244232 (rank : 16)
Query Neighborhood Hits	113	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P0M6, Q5SQT2	Gene names	H2AFY2, MACROH2A2
Domain Architecture
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AW_MOUSE
θ value	8.67504e-11 (rank : 17)	NC score	0.241829 (rank : 17)
Query Neighborhood Hits	113	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CCK0, Q3TNT4, Q925I6	Gene names	H2afy2, H2afy3
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

TNKS2_HUMAN
θ value	4.76016e-09 (rank : 18)	NC score	0.134615 (rank : 20)
Query Neighborhood Hits	113	Target Neighborhood Hits	361	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

DTX3L_HUMAN
θ value	1.53129e-07 (rank : 19)	NC score	0.134902 (rank : 19)
Query Neighborhood Hits	113	Target Neighborhood Hits	187	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

TNKS1_HUMAN
θ value	1.69304e-06 (rank : 20)	NC score	0.114106 (rank : 21)
Query Neighborhood Hits	113	Target Neighborhood Hits	477	Shared Neighborhood Hits	17
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

NMI_HUMAN
θ value	0.00665767 (rank : 21)	NC score	0.105963 (rank : 22)
Query Neighborhood Hits	113	Target Neighborhood Hits	102	Shared Neighborhood Hits	13
SwissProt Accessions	Q13287, Q53TI8, Q9BVE5	Gene names	NMI
Domain Architecture
Description	N-myc-interactor (Nmi) (N-myc and STAT interactor).

PARP3_HUMAN
θ value	0.0113563 (rank : 22)	NC score	0.140620 (rank : 18)
Query Neighborhood Hits	113	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

TRM61_HUMAN
θ value	0.0961366 (rank : 23)	NC score	0.064257 (rank : 50)
Query Neighborhood Hits	113	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q96FX7, Q8N7Q9	Gene names	TRM61, C14orf172
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 (EC 2.1.1.36) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61).

AKAP9_HUMAN
θ value	0.163984 (rank : 24)	NC score	0.036759 (rank : 57)
Query Neighborhood Hits	113	Target Neighborhood Hits	1710	Shared Neighborhood Hits	49
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

VIGLN_HUMAN
θ value	0.21417 (rank : 25)	NC score	0.057964 (rank : 53)
Query Neighborhood Hits	113	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

VIGLN_MOUSE
θ value	0.21417 (rank : 26)	NC score	0.058721 (rank : 52)
Query Neighborhood Hits	113	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

HUS1_MOUSE
θ value	0.279714 (rank : 27)	NC score	0.035843 (rank : 58)
Query Neighborhood Hits	113	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BQY8, O70543, Q6P8H5	Gene names	Hus1
Domain Architecture	No domain graphic available
Description	Checkpoint protein HUS1 (mHUS1).

TITIN_HUMAN
θ value	0.279714 (rank : 28)	NC score	0.004888 (rank : 134)
Query Neighborhood Hits	113	Target Neighborhood Hits	2923	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ANR26_MOUSE
θ value	0.47712 (rank : 29)	NC score	0.030456 (rank : 61)
Query Neighborhood Hits	113	Target Neighborhood Hits	1554	Shared Neighborhood Hits	45
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

SH3G3_HUMAN
θ value	0.47712 (rank : 30)	NC score	0.020245 (rank : 89)
Query Neighborhood Hits	113	Target Neighborhood Hits	222	Shared Neighborhood Hits	4
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

ZN287_HUMAN
θ value	0.62314 (rank : 31)	NC score	-0.000894 (rank : 140)
Query Neighborhood Hits	113	Target Neighborhood Hits	777	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBT7	Gene names	ZNF287
Domain Architecture
Description	Zinc finger protein 287.

CP1A2_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.007824 (rank : 128)
Query Neighborhood Hits	113	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	P05177, Q16754, Q6NWU5, Q9BXX7, Q9UK49	Gene names	CYP1A2
Domain Architecture
Description	Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (P450-P3) (P(3)450) (P450 4).

MYG_MOUSE
θ value	0.813845 (rank : 33)	NC score	0.030115 (rank : 62)
Query Neighborhood Hits	113	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P04247	Gene names	Mb
Domain Architecture
Description	Myoglobin.

NMI_MOUSE
θ value	0.813845 (rank : 34)	NC score	0.079112 (rank : 23)
Query Neighborhood Hits	113	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	O35309, Q99M49	Gene names	Nmi
Domain Architecture
Description	N-myc-interactor (Nmi) (N-myc and STAT interactor).

PARP1_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.053518 (rank : 54)
Query Neighborhood Hits	113	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

SYNE2_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.026604 (rank : 66)
Query Neighborhood Hits	113	Target Neighborhood Hits	1323	Shared Neighborhood Hits	42
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CJ084_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.035212 (rank : 59)
Query Neighborhood Hits	113	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C6C7	Gene names	D19Ertd737e
Domain Architecture	No domain graphic available
Description	Protein C10orf84 homolog.

KIF6_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.017525 (rank : 103)
Query Neighborhood Hits	113	Target Neighborhood Hits	271	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

MDR1_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.007989 (rank : 125)
Query Neighborhood Hits	113	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MYH9_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.020247 (rank : 88)
Query Neighborhood Hits	113	Target Neighborhood Hits	1829	Shared Neighborhood Hits	46
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RABE1_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.029329 (rank : 63)
Query Neighborhood Hits	113	Target Neighborhood Hits	1104	Shared Neighborhood Hits	40
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	1.06291 (rank : 42)	NC score	0.028909 (rank : 64)
Query Neighborhood Hits	113	Target Neighborhood Hits	1105	Shared Neighborhood Hits	39
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

ARHGC_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.011812 (rank : 114)
Query Neighborhood Hits	113	Target Neighborhood Hits	351	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CTRO_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.010484 (rank : 117)
Query Neighborhood Hits	113	Target Neighborhood Hits	2092	Shared Neighborhood Hits	46
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DICER_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.018097 (rank : 101)
Query Neighborhood Hits	113	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

MYH9_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.018393 (rank : 98)
Query Neighborhood Hits	113	Target Neighborhood Hits	1762	Shared Neighborhood Hits	44
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NUAK2_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.001438 (rank : 136)
Query Neighborhood Hits	113	Target Neighborhood Hits	874	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H093	Gene names	NUAK2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (SNF1/AMP kinase-related kinase) (SNARK).

RON_MOUSE
θ value	1.38821 (rank : 48)	NC score	0.001337 (rank : 137)
Query Neighborhood Hits	113	Target Neighborhood Hits	836	Shared Neighborhood Hits	6
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

SYCP1_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.023931 (rank : 73)
Query Neighborhood Hits	113	Target Neighborhood Hits	1313	Shared Neighborhood Hits	46
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TRM61_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.049571 (rank : 55)
Query Neighborhood Hits	113	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XC2, Q8BMD4, Q8BX33	Gene names	Trm61
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 (EC 2.1.1.36) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61).

ATRIP_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.026092 (rank : 68)
Query Neighborhood Hits	113	Target Neighborhood Hits	249	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXE1, Q8NHQ2, Q8WUG7, Q96CL3, Q9HA30	Gene names	ATRIP
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

CENPE_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.023063 (rank : 76)
Query Neighborhood Hits	113	Target Neighborhood Hits	2060	Shared Neighborhood Hits	48
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

FYCO1_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.025249 (rank : 70)
Query Neighborhood Hits	113	Target Neighborhood Hits	1059	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

MBD4_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.023392 (rank : 75)
Query Neighborhood Hits	113	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	O95243, Q7Z4T3, Q96F09	Gene names	MBD4, MED1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Methyl-CpG-binding endonuclease 1) (Mismatch-specific DNA N-glycosylase).

MRCKA_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.008957 (rank : 120)
Query Neighborhood Hits	113	Target Neighborhood Hits	1999	Shared Neighborhood Hits	43
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

SNX25_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.025803 (rank : 69)
Query Neighborhood Hits	113	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

TOLIP_MOUSE
θ value	1.81305 (rank : 57)	NC score	0.032461 (rank : 60)
Query Neighborhood Hits	113	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

GNAT1_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.008343 (rank : 122)
Query Neighborhood Hits	113	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	P11488	Gene names	GNAT1, GNATR
Domain Architecture
Description	Guanine nucleotide-binding protein G(t), alpha-1 subunit (Transducin alpha-1 chain).

KIF4A_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.018987 (rank : 96)
Query Neighborhood Hits	113	Target Neighborhood Hits	1159	Shared Neighborhood Hits	38
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MDN1_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.022601 (rank : 80)
Query Neighborhood Hits	113	Target Neighborhood Hits	662	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NSBP1_MOUSE
θ value	2.36792 (rank : 61)	NC score	0.012497 (rank : 112)
Query Neighborhood Hits	113	Target Neighborhood Hits	681	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

SH3G3_MOUSE
θ value	2.36792 (rank : 62)	NC score	0.016541 (rank : 105)
Query Neighborhood Hits	113	Target Neighborhood Hits	236	Shared Neighborhood Hits	6
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

TAF12_MOUSE
θ value	2.36792 (rank : 63)	NC score	0.028457 (rank : 65)
Query Neighborhood Hits	113	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VE65, Q3V0S7, Q9CZ11, Q9D8Q0	Gene names	Taf12
Domain Architecture
Description	Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20 kDa subunits) (TAFII-20) (TAFII20).

TXLNB_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.020317 (rank : 87)
Query Neighborhood Hits	113	Target Neighborhood Hits	912	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

CCD46_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.019598 (rank : 94)
Query Neighborhood Hits	113	Target Neighborhood Hits	1405	Shared Neighborhood Hits	41
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

PTBP2_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.015035 (rank : 109)
Query Neighborhood Hits	113	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKA9, Q8N0Z1, Q8N160, Q8NFB0, Q8NFB1, Q969N9, Q96Q76	Gene names	PTBP2, NPTB, PTB, PTBLP
Domain Architecture	No domain graphic available
Description	Polypyrimidine tract-binding protein 2 (Neurally-enriched homolog of PTB) (Neural polypyrimidine tract-binding protein) (PTB-like protein).

PTBP2_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.015056 (rank : 108)
Query Neighborhood Hits	113	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q91Z31, Q7TNW7, Q9CUW2, Q9QYC2, Q9R0V9	Gene names	Ptbp2, Brptb, Nptb
Domain Architecture	No domain graphic available
Description	Polypyrimidine tract-binding protein 2 (Brain-enriched polypyrimidine tract-binding protein) (Brain-enriched PTB) (RRM-type RNA-binding protein brPTB) (Neural polypyrimidine tract-binding protein).

T106C_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.024317 (rank : 71)
Query Neighborhood Hits	113	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q80VP8	Gene names	Tmem106c, D15Ertd405e
Domain Architecture	No domain graphic available
Description	Transmembrane protein 106C.

THNSL_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.018469 (rank : 97)
Query Neighborhood Hits	113	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

TM9S3_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.016402 (rank : 106)
Query Neighborhood Hits	113	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HD45, Q6UWE7, Q9NWL8, Q9P0G9, Q9UHW8	Gene names	TM9SF3, SMBP
Domain Architecture
Description	Transmembrane 9 superfamily protein member 3 precursor (SM-11044- binding protein) (EP70-P-iso).

ZN630_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.000140 (rank : 139)
Query Neighborhood Hits	113	Target Neighborhood Hits	737	Shared Neighborhood Hits	4
SwissProt Accessions	Q2M218	Gene names	ZNF630
Domain Architecture	No domain graphic available
Description	Zinc finger protein 630.

C8AP2_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.015441 (rank : 107)
Query Neighborhood Hits	113	Target Neighborhood Hits	548	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

GCC2_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.020245 (rank : 90)
Query Neighborhood Hits	113	Target Neighborhood Hits	1619	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GNAT1_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.007426 (rank : 129)
Query Neighborhood Hits	113	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	P20612, Q80X34	Gene names	Gnat1, Gnat-1
Domain Architecture
Description	Guanine nucleotide-binding protein G(t), alpha-1 subunit (Transducin alpha-1 chain).

KINH_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.018149 (rank : 100)
Query Neighborhood Hits	113	Target Neighborhood Hits	1082	Shared Neighborhood Hits	40
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

NOL10_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.020040 (rank : 93)
Query Neighborhood Hits	113	Target Neighborhood Hits	254	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

PARP1_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.045132 (rank : 56)
Query Neighborhood Hits	113	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

RT35_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.020165 (rank : 91)
Query Neighborhood Hits	113	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	P82673, Q32LZ1, Q6P4C6, Q7L1M6, Q96AI0, Q9H044, Q9HC14, Q9P1R5	Gene names	MRPS35, MRPS28
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35) (Mitochondrial ribosomal protein S28) (MRP-S28).

CCDC6_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.022012 (rank : 83)
Query Neighborhood Hits	113	Target Neighborhood Hits	723	Shared Neighborhood Hits	31
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CF152_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.020782 (rank : 86)
Query Neighborhood Hits	113	Target Neighborhood Hits	597	Shared Neighborhood Hits	32
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

COHA1_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.008900 (rank : 121)
Query Neighborhood Hits	113	Target Neighborhood Hits	414	Shared Neighborhood Hits	5
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CP250_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.022296 (rank : 81)
Query Neighborhood Hits	113	Target Neighborhood Hits	1583	Shared Neighborhood Hits	48
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

EP15R_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.016788 (rank : 104)
Query Neighborhood Hits	113	Target Neighborhood Hits	1135	Shared Neighborhood Hits	35
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

IF3A_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.021090 (rank : 84)
Query Neighborhood Hits	113	Target Neighborhood Hits	871	Shared Neighborhood Hits	34
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

KS6A1_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.000491 (rank : 138)
Query Neighborhood Hits	113	Target Neighborhood Hits	850	Shared Neighborhood Hits	7
SwissProt Accessions	P18653	Gene names	Rps6ka1, Rsk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

LETM1_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.022028 (rank : 82)
Query Neighborhood Hits	113	Target Neighborhood Hits	240	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

STA13_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.007414 (rank : 130)
Query Neighborhood Hits	113	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

SYNE1_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.022771 (rank : 79)
Query Neighborhood Hits	113	Target Neighborhood Hits	1484	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TMF1_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.022910 (rank : 78)
Query Neighborhood Hits	113	Target Neighborhood Hits	987	Shared Neighborhood Hits	40
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

ANR26_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.023594 (rank : 74)
Query Neighborhood Hits	113	Target Neighborhood Hits	1614	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

BIRC6_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.009421 (rank : 119)
Query Neighborhood Hits	113	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

CENPF_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.026314 (rank : 67)
Query Neighborhood Hits	113	Target Neighborhood Hits	1932	Shared Neighborhood Hits	45
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CTNA3_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.006909 (rank : 131)
Query Neighborhood Hits	113	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	Q65CL1, Q3UQ61, Q8C0N3	Gene names	Ctnna3, Catna3
Domain Architecture	No domain graphic available
Description	Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein).

DUS3L_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.010687 (rank : 116)
Query Neighborhood Hits	113	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q96G46, Q96HM5, Q9BSU4, Q9H877, Q9NPR1	Gene names	DUS3L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

EEA1_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.019321 (rank : 95)
Query Neighborhood Hits	113	Target Neighborhood Hits	1796	Shared Neighborhood Hits	47
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EMIL2_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.014050 (rank : 110)
Query Neighborhood Hits	113	Target Neighborhood Hits	485	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

ICAL_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.011998 (rank : 113)
Query Neighborhood Hits	113	Target Neighborhood Hits	275	Shared Neighborhood Hits	6
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

MACF1_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.017580 (rank : 102)
Query Neighborhood Hits	113	Target Neighborhood Hits	1341	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.020814 (rank : 85)
Query Neighborhood Hits	113	Target Neighborhood Hits	1321	Shared Neighborhood Hits	43
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MMRN1_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.022993 (rank : 77)
Query Neighborhood Hits	113	Target Neighborhood Hits	636	Shared Neighborhood Hits	29
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

NOS1_MOUSE
θ value	6.88961 (rank : 101)	NC score	0.005222 (rank : 133)
Query Neighborhood Hits	113	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

REST_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.018237 (rank : 99)
Query Neighborhood Hits	113	Target Neighborhood Hits	1605	Shared Neighborhood Hits	47
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

RHG18_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.008333 (rank : 123)
Query Neighborhood Hits	113	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

TOLIP_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.024278 (rank : 72)
Query Neighborhood Hits	113	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

IF3A_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.020158 (rank : 92)
Query Neighborhood Hits	113	Target Neighborhood Hits	875	Shared Neighborhood Hits	34
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IPO8_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.006400 (rank : 132)
Query Neighborhood Hits	113	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	O15397	Gene names	IPO8, RANBP8
Domain Architecture
Description	Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8).

KI13A_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.011366 (rank : 115)
Query Neighborhood Hits	113	Target Neighborhood Hits	359	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

RNF34_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.007847 (rank : 127)
Query Neighborhood Hits	113	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

SCFD2_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.009985 (rank : 118)
Query Neighborhood Hits	113	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WU76, Q8N5F3, Q8N8H0, Q96ED3	Gene names	SCFD2, STXBP1L1
Domain Architecture
Description	Sec1 family domain-containing protein 2 (Syntaxin-binding protein 1- like 1).

SMCA5_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.002693 (rank : 135)
Query Neighborhood Hits	113	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

STA5A_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.007939 (rank : 126)
Query Neighborhood Hits	113	Target Neighborhood Hits	128	Shared Neighborhood Hits	12
SwissProt Accessions	P42230	Gene names	Stat5a, Mgf, Mpf
Domain Architecture
Description	Signal transducer and activator of transcription 5A (Mammary gland factor).

STA5B_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.008090 (rank : 124)
Query Neighborhood Hits	113	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

TM9S3_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.012694 (rank : 111)
Query Neighborhood Hits	113	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ET30	Gene names	Tm9sf3, Smbp
Domain Architecture
Description	Transmembrane 9 superfamily protein member 3 precursor.

H2A1A_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.065953 (rank : 31)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QV6	Gene names	HIST1H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-A.

H2A1B_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.064586 (rank : 41)
Query Neighborhood Hits	113	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	P04908	Gene names	HIST1H2AB, H2AFM
Domain Architecture
Description	Histone H2A type 1-B.

H2A1C_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.064280 (rank : 49)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q93077, O00775, O00776, O00777, O00778, Q540R1	Gene names	HIST1H2AC, H2AFL
Domain Architecture
Description	Histone H2A type 1-C.

H2A1D_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.064433 (rank : 45)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	P20671, P57754, Q6FGY6	Gene names	HIST1H2AD, H2AFG
Domain Architecture
Description	Histone H2A type 1-D (H2A.3).

H2A1E_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.064462 (rank : 43)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	P28001, Q76P63	Gene names	HIST1H2AE, H2AFA
Domain Architecture
Description	Histone H2A type 1-E (H2A.2) (H2A/m).

H2A1F_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.064520 (rank : 42)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGP5	Gene names	Hist1h2af
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-F.

H2A1H_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.064678 (rank : 37)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KK5	Gene names	HIST1H2AH, HIST1H2AI
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-H.

H2A1H_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.064812 (rank : 35)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGP6	Gene names	Hist1h2ah
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-H.

H2A1J_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.064804 (rank : 36)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q99878, Q5JXQ5	Gene names	HIST1H2AJ, H2AFE
Domain Architecture
Description	Histone H2A type 1-J.

H2A1K_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.064593 (rank : 40)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGP7	Gene names	Hist1h2ak
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-K.

H2A1_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.064328 (rank : 48)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P0C0S8, P02261, Q2M1R2, Q76PA6	Gene names	HIST1H2AG, H2AFP
Domain Architecture	No domain graphic available
Description	Histone H2A type 1 (H2A.1).

H2A1_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.064462 (rank : 44)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	P22752, P10812, Q5SZZ2	Gene names	Hist1h2ab
Domain Architecture
Description	Histone H2A type 1.

H2A2A_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.064600 (rank : 38)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q6FI13, P20670	Gene names	HIST2H2AA3, H2AFO, HIST2H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2).

H2A2A_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.064600 (rank : 39)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q6GSS7, P20670, Q811M3	Gene names	Hist2h2aa1
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2) (H2a-614) (H2a-615).

H2A2B_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.065920 (rank : 32)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IUE6	Gene names	HIST2H2AB
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-B.

H2A2B_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.066270 (rank : 30)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q64522	Gene names
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-B (H2a-613A).

H2A2C_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.065228 (rank : 33)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q16777, Q6DRA7, Q8IUE5	Gene names	HIST2H2AC, H2AFQ
Domain Architecture
Description	Histone H2A type 2-C (H2A-GL101) (H2A/r).

H2A2C_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.065228 (rank : 34)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q64523, Q8CGP3	Gene names	Hist2h2ac, Hist2h2ab
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-C (H2a-613B).

H2A3_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.064384 (rank : 46)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q7L7L0	Gene names	HIST3H2A
Domain Architecture	No domain graphic available
Description	Histone H2A type 3.

H2A3_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.064384 (rank : 47)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BFU2	Gene names	Hist3h2a
Domain Architecture	No domain graphic available
Description	Histone H2A type 3.

H2AFB_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.063822 (rank : 51)
Query Neighborhood Hits	113	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P98176, Q5TZB2, Q6FG78, Q96PR7	Gene names	H2AFB3, H2ABBD, H2AFB
Domain Architecture
Description	Histone H2A-Bbd (H2A Barr body-deficient) (H2A.Bbd).

H2AV_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.069199 (rank : 26)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q71UI9, Q59GV8, Q6PK98	Gene names	H2AFV, H2AV
Domain Architecture	No domain graphic available
Description	Histone H2AV (H2A.F/Z).

H2AV_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.069199 (rank : 27)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q3THW5, Q5NC92, Q6ZWU0	Gene names	H2afv, H2av
Domain Architecture	No domain graphic available
Description	Histone H2AV (H2A.F/Z).

H2AX_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.067347 (rank : 29)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P16104, Q4ZGJ7, Q6IAS5	Gene names	H2AFX, H2AX
Domain Architecture
Description	Histone H2A.x (H2a/x).

H2AX_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.067617 (rank : 28)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P27661	Gene names	H2afx, H2a.x, H2ax, Hist5-2ax
Domain Architecture
Description	Histone H2A.x (H2a/x).

H2AZ_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.069319 (rank : 24)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P0C0S5, P17317, Q6I9U0	Gene names	H2AFZ, H2AZ
Domain Architecture	No domain graphic available
Description	Histone H2A.Z (H2A/z).

H2AZ_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.069319 (rank : 25)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P0C0S6, P17317, Q3UA55, Q3UK43, Q68FD2	Gene names	H2afz, H2az
Domain Architecture	No domain graphic available
Description	Histone H2A.Z (H2A/z).

Hits sorted by NC score

PAR14_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	113
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PAR14_HUMAN
NC score	0.983019 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	113	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

PAR15_HUMAN
NC score	0.925679 (rank : 3)	θ value	8.73085e-104 (rank : 3)
Query Neighborhood Hits	113	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q460N3, Q8N1K3	Gene names	PARP15, BAL3
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 15 (EC 2.4.2.30) (PARP-15) (B-aggressive lymphoma protein 3).

PARP9_HUMAN
NC score	0.810188 (rank : 4)	θ value	7.75577e-52 (rank : 5)
Query Neighborhood Hits	113	Target Neighborhood Hits	60	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

PARP9_MOUSE
NC score	0.807987 (rank : 5)	θ value	1.36585e-56 (rank : 4)
Query Neighborhood Hits	113	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CAS9, Q99LF9	Gene names	Parp9, Bal
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein homolog).

PARPT_MOUSE
NC score	0.699786 (rank : 6)	θ value	6.38894e-30 (rank : 10)
Query Neighborhood Hits	113	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

PARPT_HUMAN
NC score	0.699559 (rank : 7)	θ value	6.38894e-30 (rank : 9)
Query Neighborhood Hits	113	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

PAR12_MOUSE
NC score	0.689306 (rank : 8)	θ value	8.91499e-32 (rank : 7)
Query Neighborhood Hits	113	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PAR12_HUMAN
NC score	0.685490 (rank : 9)	θ value	1.98606e-31 (rank : 8)
Query Neighborhood Hits	113	Target Neighborhood Hits	42	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PAR10_HUMAN
NC score	0.679239 (rank : 10)	θ value	4.72714e-33 (rank : 6)
Query Neighborhood Hits	113	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

ZCC2_HUMAN
NC score	0.641376 (rank : 11)	θ value	6.62687e-19 (rank : 11)
Query Neighborhood Hits	113	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

LRP16_HUMAN
NC score	0.546403 (rank : 12)	θ value	9.56915e-18 (rank : 12)
Query Neighborhood Hits	113	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BQ69, Q9UH96	Gene names	LRP16
Domain Architecture
Description	Protein LRP16.

LRP16_MOUSE
NC score	0.534480 (rank : 13)	θ value	2.60593e-15 (rank : 13)
Query Neighborhood Hits	113	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q922B1	Gene names	Lrp16
Domain Architecture
Description	Protein LRP16.

H2AY_HUMAN
NC score	0.296154 (rank : 14)	θ value	3.76295e-14 (rank : 14)
Query Neighborhood Hits	113	Target Neighborhood Hits	48	Shared Neighborhood Hits	11
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

H2AY_MOUSE
NC score	0.295573 (rank : 15)	θ value	4.91457e-14 (rank : 15)
Query Neighborhood Hits	113	Target Neighborhood Hits	49	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

H2AW_HUMAN
NC score	0.244232 (rank : 16)	θ value	8.67504e-11 (rank : 16)
Query Neighborhood Hits	113	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P0M6, Q5SQT2	Gene names	H2AFY2, MACROH2A2
Domain Architecture
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AW_MOUSE
NC score	0.241829 (rank : 17)	θ value	8.67504e-11 (rank : 17)
Query Neighborhood Hits	113	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CCK0, Q3TNT4, Q925I6	Gene names	H2afy2, H2afy3
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

PARP3_HUMAN
NC score	0.140620 (rank : 18)	θ value	0.0113563 (rank : 22)
Query Neighborhood Hits	113	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

DTX3L_HUMAN
NC score	0.134902 (rank : 19)	θ value	1.53129e-07 (rank : 19)
Query Neighborhood Hits	113	Target Neighborhood Hits	187	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

TNKS2_HUMAN
NC score	0.134615 (rank : 20)	θ value	4.76016e-09 (rank : 18)
Query Neighborhood Hits	113	Target Neighborhood Hits	361	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TNKS1_HUMAN
NC score	0.114106 (rank : 21)	θ value	1.69304e-06 (rank : 20)
Query Neighborhood Hits	113	Target Neighborhood Hits	477	Shared Neighborhood Hits	17
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

NMI_HUMAN
NC score	0.105963 (rank : 22)	θ value	0.00665767 (rank : 21)
Query Neighborhood Hits	113	Target Neighborhood Hits	102	Shared Neighborhood Hits	13
SwissProt Accessions	Q13287, Q53TI8, Q9BVE5	Gene names	NMI
Domain Architecture
Description	N-myc-interactor (Nmi) (N-myc and STAT interactor).

NMI_MOUSE
NC score	0.079112 (rank : 23)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	113	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	O35309, Q99M49	Gene names	Nmi
Domain Architecture
Description	N-myc-interactor (Nmi) (N-myc and STAT interactor).

H2AZ_HUMAN
NC score	0.069319 (rank : 24)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P0C0S5, P17317, Q6I9U0	Gene names	H2AFZ, H2AZ
Domain Architecture	No domain graphic available
Description	Histone H2A.Z (H2A/z).

H2AZ_MOUSE
NC score	0.069319 (rank : 25)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P0C0S6, P17317, Q3UA55, Q3UK43, Q68FD2	Gene names	H2afz, H2az
Domain Architecture	No domain graphic available
Description	Histone H2A.Z (H2A/z).

H2AV_HUMAN
NC score	0.069199 (rank : 26)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q71UI9, Q59GV8, Q6PK98	Gene names	H2AFV, H2AV
Domain Architecture	No domain graphic available
Description	Histone H2AV (H2A.F/Z).

H2AV_MOUSE
NC score	0.069199 (rank : 27)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q3THW5, Q5NC92, Q6ZWU0	Gene names	H2afv, H2av
Domain Architecture	No domain graphic available
Description	Histone H2AV (H2A.F/Z).

H2AX_MOUSE
NC score	0.067617 (rank : 28)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P27661	Gene names	H2afx, H2a.x, H2ax, Hist5-2ax
Domain Architecture
Description	Histone H2A.x (H2a/x).

H2AX_HUMAN
NC score	0.067347 (rank : 29)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P16104, Q4ZGJ7, Q6IAS5	Gene names	H2AFX, H2AX
Domain Architecture
Description	Histone H2A.x (H2a/x).

H2A2B_MOUSE
NC score	0.066270 (rank : 30)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q64522	Gene names
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-B (H2a-613A).

H2A1A_HUMAN
NC score	0.065953 (rank : 31)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QV6	Gene names	HIST1H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-A.

H2A2B_HUMAN
NC score	0.065920 (rank : 32)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IUE6	Gene names	HIST2H2AB
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-B.

H2A2C_HUMAN
NC score	0.065228 (rank : 33)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q16777, Q6DRA7, Q8IUE5	Gene names	HIST2H2AC, H2AFQ
Domain Architecture
Description	Histone H2A type 2-C (H2A-GL101) (H2A/r).

H2A2C_MOUSE
NC score	0.065228 (rank : 34)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q64523, Q8CGP3	Gene names	Hist2h2ac, Hist2h2ab
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-C (H2a-613B).

H2A1H_MOUSE
NC score	0.064812 (rank : 35)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGP6	Gene names	Hist1h2ah
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-H.

H2A1J_HUMAN
NC score	0.064804 (rank : 36)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q99878, Q5JXQ5	Gene names	HIST1H2AJ, H2AFE
Domain Architecture
Description	Histone H2A type 1-J.

H2A1H_HUMAN
NC score	0.064678 (rank : 37)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KK5	Gene names	HIST1H2AH, HIST1H2AI
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-H.

H2A2A_HUMAN
NC score	0.064600 (rank : 38)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q6FI13, P20670	Gene names	HIST2H2AA3, H2AFO, HIST2H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2).

H2A2A_MOUSE
NC score	0.064600 (rank : 39)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q6GSS7, P20670, Q811M3	Gene names	Hist2h2aa1
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2) (H2a-614) (H2a-615).

H2A1K_MOUSE
NC score	0.064593 (rank : 40)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGP7	Gene names	Hist1h2ak
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-K.

H2A1B_HUMAN
NC score	0.064586 (rank : 41)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	113	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	P04908	Gene names	HIST1H2AB, H2AFM
Domain Architecture
Description	Histone H2A type 1-B.

H2A1F_MOUSE
NC score	0.064520 (rank : 42)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGP5	Gene names	Hist1h2af
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-F.

H2A1E_HUMAN
NC score	0.064462 (rank : 43)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	P28001, Q76P63	Gene names	HIST1H2AE, H2AFA
Domain Architecture
Description	Histone H2A type 1-E (H2A.2) (H2A/m).

H2A1_MOUSE
NC score	0.064462 (rank : 44)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	P22752, P10812, Q5SZZ2	Gene names	Hist1h2ab
Domain Architecture
Description	Histone H2A type 1.

H2A1D_HUMAN
NC score	0.064433 (rank : 45)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	P20671, P57754, Q6FGY6	Gene names	HIST1H2AD, H2AFG
Domain Architecture
Description	Histone H2A type 1-D (H2A.3).

H2A3_HUMAN
NC score	0.064384 (rank : 46)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q7L7L0	Gene names	HIST3H2A
Domain Architecture	No domain graphic available
Description	Histone H2A type 3.

H2A3_MOUSE
NC score	0.064384 (rank : 47)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BFU2	Gene names	Hist3h2a
Domain Architecture	No domain graphic available
Description	Histone H2A type 3.

H2A1_HUMAN
NC score	0.064328 (rank : 48)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P0C0S8, P02261, Q2M1R2, Q76PA6	Gene names	HIST1H2AG, H2AFP
Domain Architecture	No domain graphic available
Description	Histone H2A type 1 (H2A.1).

H2A1C_HUMAN
NC score	0.064280 (rank : 49)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	113	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q93077, O00775, O00776, O00777, O00778, Q540R1	Gene names	HIST1H2AC, H2AFL
Domain Architecture
Description	Histone H2A type 1-C.

TRM61_HUMAN
NC score	0.064257 (rank : 50)	θ value	0.0961366 (rank : 23)
Query Neighborhood Hits	113	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q96FX7, Q8N7Q9	Gene names	TRM61, C14orf172
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 (EC 2.1.1.36) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61).

H2AFB_HUMAN
NC score	0.063822 (rank : 51)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	113	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P98176, Q5TZB2, Q6FG78, Q96PR7	Gene names	H2AFB3, H2ABBD, H2AFB
Domain Architecture
Description	Histone H2A-Bbd (H2A Barr body-deficient) (H2A.Bbd).

VIGLN_MOUSE
NC score	0.058721 (rank : 52)	θ value	0.21417 (rank : 26)
Query Neighborhood Hits	113	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

VIGLN_HUMAN
NC score	0.057964 (rank : 53)	θ value	0.21417 (rank : 25)
Query Neighborhood Hits	113	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

PARP1_HUMAN
NC score	0.053518 (rank : 54)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	113	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

TRM61_MOUSE
NC score	0.049571 (rank : 55)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	113	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XC2, Q8BMD4, Q8BX33	Gene names	Trm61
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 (EC 2.1.1.36) (tRNA(m1A58)-methyltransferase subunit TRM61) (tRNA(m1A58)MTase subunit TRM61).

PARP1_MOUSE
NC score	0.045132 (rank : 56)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	113	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

AKAP9_HUMAN
NC score	0.036759 (rank : 57)	θ value	0.163984 (rank : 24)
Query Neighborhood Hits	113	Target Neighborhood Hits	1710	Shared Neighborhood Hits	49
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

HUS1_MOUSE
NC score	0.035843 (rank : 58)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	113	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BQY8, O70543, Q6P8H5	Gene names	Hus1
Domain Architecture	No domain graphic available
Description	Checkpoint protein HUS1 (mHUS1).

CJ084_MOUSE
NC score	0.035212 (rank : 59)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	113	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C6C7	Gene names	D19Ertd737e
Domain Architecture	No domain graphic available
Description	Protein C10orf84 homolog.

TOLIP_MOUSE
NC score	0.032461 (rank : 60)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	113	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ06, Q543N1, Q9D5P5	Gene names	Tollip
Domain Architecture
Description	Toll-interacting protein.

ANR26_MOUSE
NC score	0.030456 (rank : 61)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	113	Target Neighborhood Hits	1554	Shared Neighborhood Hits	45
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MYG_MOUSE
NC score	0.030115 (rank : 62)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	113	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P04247	Gene names	Mb
Domain Architecture
Description	Myoglobin.

RABE1_HUMAN
NC score	0.029329 (rank : 63)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	113	Target Neighborhood Hits	1104	Shared Neighborhood Hits	40
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
NC score	0.028909 (rank : 64)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	113	Target Neighborhood Hits	1105	Shared Neighborhood Hits	39
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

TAF12_MOUSE
NC score	0.028457 (rank : 65)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	113	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VE65, Q3V0S7, Q9CZ11, Q9D8Q0	Gene names	Taf12
Domain Architecture
Description	Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20 kDa subunits) (TAFII-20) (TAFII20).

SYNE2_HUMAN
NC score	0.026604 (rank : 66)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	113	Target Neighborhood Hits	1323	Shared Neighborhood Hits	42
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CENPF_HUMAN
NC score	0.026314 (rank : 67)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	113	Target Neighborhood Hits	1932	Shared Neighborhood Hits	45
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

ATRIP_HUMAN
NC score	0.026092 (rank : 68)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	113	Target Neighborhood Hits	249	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXE1, Q8NHQ2, Q8WUG7, Q96CL3, Q9HA30	Gene names	ATRIP
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

SNX25_HUMAN
NC score	0.025803 (rank : 69)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	113	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3E2	Gene names	SNX25
Domain Architecture
Description	Sorting nexin-25.

FYCO1_MOUSE
NC score	0.025249 (rank : 70)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	113	Target Neighborhood Hits	1059	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

T106C_MOUSE
NC score	0.024317 (rank : 71)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	113	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q80VP8	Gene names	Tmem106c, D15Ertd405e
Domain Architecture	No domain graphic available
Description	Transmembrane protein 106C.

TOLIP_HUMAN
NC score	0.024278 (rank : 72)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	113	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0E2, Q9H9E6, Q9UJ69	Gene names	TOLLIP
Domain Architecture
Description	Toll-interacting protein.

SYCP1_HUMAN
NC score	0.023931 (rank : 73)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	113	Target Neighborhood Hits	1313	Shared Neighborhood Hits	46
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ANR26_HUMAN
NC score	0.023594 (rank : 74)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	113	Target Neighborhood Hits	1614	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MBD4_HUMAN
NC score	0.023392 (rank : 75)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	113	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	O95243, Q7Z4T3, Q96F09	Gene names	MBD4, MED1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Methyl-CpG-binding endonuclease 1) (Mismatch-specific DNA N-glycosylase).

CENPE_HUMAN
NC score	0.023063 (rank : 76)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	113	Target Neighborhood Hits	2060	Shared Neighborhood Hits	48
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MMRN1_HUMAN
NC score	0.022993 (rank : 77)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	113	Target Neighborhood Hits	636	Shared Neighborhood Hits	29
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

TMF1_HUMAN
NC score	0.022910 (rank : 78)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	113	Target Neighborhood Hits	987	Shared Neighborhood Hits	40
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

SYNE1_HUMAN
NC score	0.022771 (rank : 79)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	113	Target Neighborhood Hits	1484	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

MDN1_HUMAN
NC score	0.022601 (rank : 80)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	113	Target Neighborhood Hits	662	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

CP250_MOUSE
NC score	0.022296 (rank : 81)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	113	Target Neighborhood Hits	1583	Shared Neighborhood Hits	48
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

LETM1_MOUSE
NC score	0.022028 (rank : 82)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	113	Target Neighborhood Hits	240	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

CCDC6_HUMAN
NC score	0.022012 (rank : 83)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	113	Target Neighborhood Hits	723	Shared Neighborhood Hits	31
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

IF3A_MOUSE
NC score	0.021090 (rank : 84)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	113	Target Neighborhood Hits	871	Shared Neighborhood Hits	34
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

MACF4_HUMAN
NC score	0.020814 (rank : 85)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	113	Target Neighborhood Hits	1321	Shared Neighborhood Hits	43
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

CF152_MOUSE
NC score	0.020782 (rank : 86)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	113	Target Neighborhood Hits	597	Shared Neighborhood Hits	32
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

TXLNB_HUMAN
NC score	0.020317 (rank : 87)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	113	Target Neighborhood Hits	912	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

MYH9_MOUSE
NC score	0.020247 (rank : 88)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	113	Target Neighborhood Hits	1829	Shared Neighborhood Hits	46
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SH3G3_HUMAN
NC score	0.020245 (rank : 89)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	113	Target Neighborhood Hits	222	Shared Neighborhood Hits	4
SwissProt Accessions	Q99963, O43553, O43554	Gene names	SH3GL3, CNSA3, SH3D2C
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (EEN-B2).

GCC2_MOUSE
NC score	0.020245 (rank : 90)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	113	Target Neighborhood Hits	1619	Shared Neighborhood Hits	44
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

RT35_HUMAN
NC score	0.020165 (rank : 91)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	113	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	P82673, Q32LZ1, Q6P4C6, Q7L1M6, Q96AI0, Q9H044, Q9HC14, Q9P1R5	Gene names	MRPS35, MRPS28
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35) (Mitochondrial ribosomal protein S28) (MRP-S28).

IF3A_HUMAN
NC score	0.020158 (rank : 92)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	113	Target Neighborhood Hits	875	Shared Neighborhood Hits	34
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

NOL10_HUMAN
NC score	0.020040 (rank : 93)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	113	Target Neighborhood Hits	254	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BSC4, Q53RC9, Q96TA5, Q9H7Y7, Q9H855	Gene names	NOL10
Domain Architecture	No domain graphic available
Description	Nucleolar protein 10.

CCD46_MOUSE
NC score	0.019598 (rank : 94)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	113	Target Neighborhood Hits	1405	Shared Neighborhood Hits	41
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

EEA1_HUMAN
NC score	0.019321 (rank : 95)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	113	Target Neighborhood Hits	1796	Shared Neighborhood Hits	47
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

KIF4A_HUMAN
NC score	0.018987 (rank : 96)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	113	Target Neighborhood Hits	1159	Shared Neighborhood Hits	38
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

THNSL_HUMAN
NC score	0.018469 (rank : 97)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	113	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

MYH9_HUMAN
NC score	0.018393 (rank : 98)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	113	Target Neighborhood Hits	1762	Shared Neighborhood Hits	44
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

REST_HUMAN
NC score	0.018237 (rank : 99)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	113	Target Neighborhood Hits	1605	Shared Neighborhood Hits	47
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

KINH_MOUSE
NC score	0.018149 (rank : 100)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	113	Target Neighborhood Hits	1082	Shared Neighborhood Hits	40
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

DICER_HUMAN
NC score	0.018097 (rank : 101)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	113	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

MACF1_HUMAN
NC score	0.017580 (rank : 102)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	113	Target Neighborhood Hits	1341	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

KIF6_HUMAN
NC score	0.017525 (rank : 103)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	113	Target Neighborhood Hits	271	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

EP15R_MOUSE
NC score	0.016788 (rank : 104)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	113	Target Neighborhood Hits	1135	Shared Neighborhood Hits	35
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

SH3G3_MOUSE
NC score	0.016541 (rank : 105)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	113	Target Neighborhood Hits	236	Shared Neighborhood Hits	6
SwissProt Accessions	Q62421	Gene names	Sh3gl3, Sh3d2c, Sh3d2c2
Domain Architecture
Description	SH3-containing GRB2-like protein 3 (Endophilin-3) (Endophilin-A3) (SH3 domain protein 2C) (SH3p13).

TM9S3_HUMAN
NC score	0.016402 (rank : 106)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	113	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HD45, Q6UWE7, Q9NWL8, Q9P0G9, Q9UHW8	Gene names	TM9SF3, SMBP
Domain Architecture
Description	Transmembrane 9 superfamily protein member 3 precursor (SM-11044- binding protein) (EP70-P-iso).

C8AP2_HUMAN
NC score	0.015441 (rank : 107)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	113	Target Neighborhood Hits	548	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

PTBP2_MOUSE
NC score	0.015056 (rank : 108)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	113	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q91Z31, Q7TNW7, Q9CUW2, Q9QYC2, Q9R0V9	Gene names	Ptbp2, Brptb, Nptb
Domain Architecture	No domain graphic available
Description	Polypyrimidine tract-binding protein 2 (Brain-enriched polypyrimidine tract-binding protein) (Brain-enriched PTB) (RRM-type RNA-binding protein brPTB) (Neural polypyrimidine tract-binding protein).

PTBP2_HUMAN
NC score	0.015035 (rank : 109)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	113	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKA9, Q8N0Z1, Q8N160, Q8NFB0, Q8NFB1, Q969N9, Q96Q76	Gene names	PTBP2, NPTB, PTB, PTBLP
Domain Architecture	No domain graphic available
Description	Polypyrimidine tract-binding protein 2 (Neurally-enriched homolog of PTB) (Neural polypyrimidine tract-binding protein) (PTB-like protein).

EMIL2_MOUSE
NC score	0.014050 (rank : 110)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	113	Target Neighborhood Hits	485	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

TM9S3_MOUSE
NC score	0.012694 (rank : 111)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	113	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ET30	Gene names	Tm9sf3, Smbp
Domain Architecture
Description	Transmembrane 9 superfamily protein member 3 precursor.

NSBP1_MOUSE
NC score	0.012497 (rank : 112)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	113	Target Neighborhood Hits	681	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

ICAL_HUMAN
NC score	0.011998 (rank : 113)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	113	Target Neighborhood Hits	275	Shared Neighborhood Hits	6
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

ARHGC_HUMAN
NC score	0.011812 (rank : 114)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	113	Target Neighborhood Hits	351	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

KI13A_HUMAN
NC score	0.011366 (rank : 115)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	113	Target Neighborhood Hits	359	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

DUS3L_HUMAN
NC score	0.010687 (rank : 116)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	113	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q96G46, Q96HM5, Q9BSU4, Q9H877, Q9NPR1	Gene names	DUS3L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

CTRO_HUMAN
NC score	0.010484 (rank : 117)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	113	Target Neighborhood Hits	2092	Shared Neighborhood Hits	46
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

SCFD2_HUMAN
NC score	0.009985 (rank : 118)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	113	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WU76, Q8N5F3, Q8N8H0, Q96ED3	Gene names	SCFD2, STXBP1L1
Domain Architecture
Description	Sec1 family domain-containing protein 2 (Syntaxin-binding protein 1- like 1).

BIRC6_HUMAN
NC score	0.009421 (rank : 119)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	113	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

MRCKA_HUMAN
NC score	0.008957 (rank : 120)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	113	Target Neighborhood Hits	1999	Shared Neighborhood Hits	43
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

COHA1_MOUSE
NC score	0.008900 (rank : 121)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	113	Target Neighborhood Hits	414	Shared Neighborhood Hits	5
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

GNAT1_HUMAN
NC score	0.008343 (rank : 122)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	113	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	P11488	Gene names	GNAT1, GNATR
Domain Architecture
Description	Guanine nucleotide-binding protein G(t), alpha-1 subunit (Transducin alpha-1 chain).

RHG18_HUMAN
NC score	0.008333 (rank : 123)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	113	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

STA5B_MOUSE
NC score	0.008090 (rank : 124)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	113	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

MDR1_HUMAN
NC score	0.007989 (rank : 125)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	113	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

STA5A_MOUSE
NC score	0.007939 (rank : 126)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	113	Target Neighborhood Hits	128	Shared Neighborhood Hits	12
SwissProt Accessions	P42230	Gene names	Stat5a, Mgf, Mpf
Domain Architecture
Description	Signal transducer and activator of transcription 5A (Mammary gland factor).

RNF34_MOUSE
NC score	0.007847 (rank : 127)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	113	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

CP1A2_HUMAN
NC score	0.007824 (rank : 128)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	113	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	P05177, Q16754, Q6NWU5, Q9BXX7, Q9UK49	Gene names	CYP1A2
Domain Architecture
Description	Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (P450-P3) (P(3)450) (P450 4).

GNAT1_MOUSE
NC score	0.007426 (rank : 129)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	113	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	P20612, Q80X34	Gene names	Gnat1, Gnat-1
Domain Architecture
Description	Guanine nucleotide-binding protein G(t), alpha-1 subunit (Transducin alpha-1 chain).

STA13_HUMAN
NC score	0.007414 (rank : 130)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	113	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

CTNA3_MOUSE
NC score	0.006909 (rank : 131)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	113	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	Q65CL1, Q3UQ61, Q8C0N3	Gene names	Ctnna3, Catna3
Domain Architecture	No domain graphic available
Description	Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein).

IPO8_HUMAN
NC score	0.006400 (rank : 132)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	113	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	O15397	Gene names	IPO8, RANBP8
Domain Architecture
Description	Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8).

NOS1_MOUSE
NC score	0.005222 (rank : 133)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	113	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

TITIN_HUMAN
NC score	0.004888 (rank : 134)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	113	Target Neighborhood Hits	2923	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SMCA5_HUMAN
NC score	0.002693 (rank : 135)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	113	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

NUAK2_HUMAN
NC score	0.001438 (rank : 136)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	113	Target Neighborhood Hits	874	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H093	Gene names	NUAK2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (SNF1/AMP kinase-related kinase) (SNARK).

RON_MOUSE
NC score	0.001337 (rank : 137)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	113	Target Neighborhood Hits	836	Shared Neighborhood Hits	6
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

KS6A1_MOUSE
NC score	0.000491 (rank : 138)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	113	Target Neighborhood Hits	850	Shared Neighborhood Hits	7
SwissProt Accessions	P18653	Gene names	Rps6ka1, Rsk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

ZN630_HUMAN
NC score	0.000140 (rank : 139)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	113	Target Neighborhood Hits	737	Shared Neighborhood Hits	4
SwissProt Accessions	Q2M218	Gene names	ZNF630
Domain Architecture	No domain graphic available
Description	Zinc finger protein 630.

ZN287_HUMAN
NC score	-0.000894 (rank : 140)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	113	Target Neighborhood Hits	777	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBT7	Gene names	ZNF287
Domain Architecture
Description	Zinc finger protein 287.