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Network neighborhood for query Sequence : MBD4_HUMAN

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MBD4_HUMAN
SwissProt Accessions	O95243, Q7Z4T3, Q96F09	Gene names	MBD4, MED1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Methyl-CpG-binding endonuclease 1) (Mismatch-specific DNA N-glycosylase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MBD4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	O95243, Q7Z4T3, Q96F09	Gene names	MBD4, MED1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Methyl-CpG-binding endonuclease 1) (Mismatch-specific DNA N-glycosylase).

MBD4_MOUSE
θ value	0 (rank : 2)	NC score	0.968032 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z2D7, Q792D2, Q8R3R3	Gene names	Mbd4
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase).

MECP2_HUMAN
θ value	3.76295e-14 (rank : 3)	NC score	0.585285 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MECP2_MOUSE
θ value	3.76295e-14 (rank : 4)	NC score	0.579929 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MBD3_HUMAN
θ value	8.40245e-06 (rank : 5)	NC score	0.362276 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	O95983, Q6PIL9, Q6PJZ9, Q86XF4	Gene names	MBD3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MBD3_MOUSE
θ value	8.40245e-06 (rank : 6)	NC score	0.362631 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2D8, Q792D3, Q8CFJ1	Gene names	Mbd3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MBD2_HUMAN
θ value	1.87187e-05 (rank : 7)	NC score	0.368141 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBB5, O95242, Q9UIS8	Gene names	MBD2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) (Demethylase) (DMTase).

MBD2_MOUSE
θ value	3.19293e-05 (rank : 8)	NC score	0.368792 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2E1, Q811D9, Q9Z2D9	Gene names	Mbd2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2).

IWS1_MOUSE
θ value	0.00134147 (rank : 9)	NC score	0.063127 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	1258	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MBD1_MOUSE
θ value	0.00869519 (rank : 10)	NC score	0.257895 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

MBD1_HUMAN
θ value	0.0148317 (rank : 11)	NC score	0.247904 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	77	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

BAZ2B_HUMAN
θ value	0.125558 (rank : 12)	NC score	0.056131 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	803	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CIR_MOUSE
θ value	0.125558 (rank : 13)	NC score	0.066267 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	255	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

PCLO_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.024004 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	2046	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PPR3A_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.050557 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q16821, O43476, Q75LN8, Q7KYM8, Q86UI6	Gene names	PPP1R3A, PP1G
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit).

ATRX_MOUSE
θ value	0.62314 (rank : 16)	NC score	0.030995 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	682	Shared Neighborhood Hits	14
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CCD39_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.016088 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	868	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

ARS2_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.039249 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	186	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

BRCA2_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.032763 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	202	Shared Neighborhood Hits	4
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

HNRPD_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.022024 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	221	Shared Neighborhood Hits	4
SwissProt Accessions	Q14103, Q01858, Q14100, Q14101, Q14102	Gene names	HNRPD, AUF1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1).

HNRPD_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.022058 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	220	Shared Neighborhood Hits	4
SwissProt Accessions	Q60668, Q60667, Q80ZJ0, Q91X94	Gene names	Hnrpd, Auf1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1).

PRP4B_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.006512 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	1030	Shared Neighborhood Hits	6
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

PAR14_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.023392 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

MYH14_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.005546 (rank : 43)
Query Neighborhood Hits	41	Target Neighborhood Hits	1225	Shared Neighborhood Hits	7
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

COHA1_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.010862 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	414	Shared Neighborhood Hits	4
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

MBD6_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.037052 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	349	Shared Neighborhood Hits	5
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MPDZ_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.010183 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	298	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

STAB2_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.007065 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	534	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

BPAEA_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.007671 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	1369	Shared Neighborhood Hits	9
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CA026_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.022550 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

RPGR1_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.018914 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	713	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

ZCH10_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.043793 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

MINT_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.016079 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	1291	Shared Neighborhood Hits	14
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MTG8_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.012788 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

TLE1_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.007903 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	485	Shared Neighborhood Hits	5
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

VRK2_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.006925 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	582	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y07, Q49AK9, Q53EU9, Q86Y08, Q86Y09, Q86Y10, Q86Y11, Q86Y12, Q8IXI5, Q99987	Gene names	VRK2
Domain Architecture
Description	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2).

CASZ1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.011819 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	473	Shared Neighborhood Hits	3
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

DDX21_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.006595 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	308	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

M3K9_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.001763 (rank : 44)
Query Neighborhood Hits	41	Target Neighborhood Hits	1123	Shared Neighborhood Hits	4
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

NKTR_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.013679 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	658	Shared Neighborhood Hits	13
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

U2AFM_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.009389 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	577	Shared Neighborhood Hits	6
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

MB3L1_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.139853 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWY6	Gene names	MBD3L1, MBD3L
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1).

MB3L1_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.125115 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D9H3, Q6P8W5, Q9D2S3	Gene names	Mbd3l1, Mbd3l
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1).

MB3L2_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.114751 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NHZ7	Gene names	MBD3L2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 2 (MBD3-like 2).

Hits sorted by NC score

MBD4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	O95243, Q7Z4T3, Q96F09	Gene names	MBD4, MED1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Methyl-CpG-binding endonuclease 1) (Mismatch-specific DNA N-glycosylase).

MBD4_MOUSE
NC score	0.968032 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z2D7, Q792D2, Q8R3R3	Gene names	Mbd4
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase).

MECP2_HUMAN
NC score	0.585285 (rank : 3)	θ value	3.76295e-14 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MECP2_MOUSE
NC score	0.579929 (rank : 4)	θ value	3.76295e-14 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MBD2_MOUSE
NC score	0.368792 (rank : 5)	θ value	3.19293e-05 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2E1, Q811D9, Q9Z2D9	Gene names	Mbd2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2).

MBD2_HUMAN
NC score	0.368141 (rank : 6)	θ value	1.87187e-05 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBB5, O95242, Q9UIS8	Gene names	MBD2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) (Demethylase) (DMTase).

MBD3_MOUSE
NC score	0.362631 (rank : 7)	θ value	8.40245e-06 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2D8, Q792D3, Q8CFJ1	Gene names	Mbd3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MBD3_HUMAN
NC score	0.362276 (rank : 8)	θ value	8.40245e-06 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	O95983, Q6PIL9, Q6PJZ9, Q86XF4	Gene names	MBD3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MBD1_MOUSE
NC score	0.257895 (rank : 9)	θ value	0.00869519 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

MBD1_HUMAN
NC score	0.247904 (rank : 10)	θ value	0.0148317 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	77	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

MB3L1_HUMAN
NC score	0.139853 (rank : 11)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWY6	Gene names	MBD3L1, MBD3L
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1).

MB3L1_MOUSE
NC score	0.125115 (rank : 12)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	41	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D9H3, Q6P8W5, Q9D2S3	Gene names	Mbd3l1, Mbd3l
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1).

MB3L2_HUMAN
NC score	0.114751 (rank : 13)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NHZ7	Gene names	MBD3L2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 2 (MBD3-like 2).

CIR_MOUSE
NC score	0.066267 (rank : 14)	θ value	0.125558 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	255	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

IWS1_MOUSE
NC score	0.063127 (rank : 15)	θ value	0.00134147 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	1258	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BAZ2B_HUMAN
NC score	0.056131 (rank : 16)	θ value	0.125558 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	803	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

PPR3A_HUMAN
NC score	0.050557 (rank : 17)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q16821, O43476, Q75LN8, Q7KYM8, Q86UI6	Gene names	PPP1R3A, PP1G
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit).

ZCH10_MOUSE
NC score	0.043793 (rank : 18)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

ARS2_HUMAN
NC score	0.039249 (rank : 19)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	186	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

MBD6_HUMAN
NC score	0.037052 (rank : 20)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	349	Shared Neighborhood Hits	5
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

BRCA2_HUMAN
NC score	0.032763 (rank : 21)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	202	Shared Neighborhood Hits	4
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

ATRX_MOUSE
NC score	0.030995 (rank : 22)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	682	Shared Neighborhood Hits	14
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

PCLO_HUMAN
NC score	0.024004 (rank : 23)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	2046	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PAR14_MOUSE
NC score	0.023392 (rank : 24)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

CA026_MOUSE
NC score	0.022550 (rank : 25)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

HNRPD_MOUSE
NC score	0.022058 (rank : 26)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	220	Shared Neighborhood Hits	4
SwissProt Accessions	Q60668, Q60667, Q80ZJ0, Q91X94	Gene names	Hnrpd, Auf1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1).

HNRPD_HUMAN
NC score	0.022024 (rank : 27)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	221	Shared Neighborhood Hits	4
SwissProt Accessions	Q14103, Q01858, Q14100, Q14101, Q14102	Gene names	HNRPD, AUF1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1).

RPGR1_MOUSE
NC score	0.018914 (rank : 28)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	713	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CCD39_HUMAN
NC score	0.016088 (rank : 29)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	868	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

MINT_HUMAN
NC score	0.016079 (rank : 30)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	1291	Shared Neighborhood Hits	14
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NKTR_HUMAN
NC score	0.013679 (rank : 31)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	658	Shared Neighborhood Hits	13
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

MTG8_HUMAN
NC score	0.012788 (rank : 32)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

CASZ1_HUMAN
NC score	0.011819 (rank : 33)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	473	Shared Neighborhood Hits	3
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

COHA1_MOUSE
NC score	0.010862 (rank : 34)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	414	Shared Neighborhood Hits	4
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

MPDZ_MOUSE
NC score	0.010183 (rank : 35)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	298	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

U2AFM_HUMAN
NC score	0.009389 (rank : 36)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	577	Shared Neighborhood Hits	6
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

TLE1_HUMAN
NC score	0.007903 (rank : 37)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	485	Shared Neighborhood Hits	5
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

BPAEA_HUMAN
NC score	0.007671 (rank : 38)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	1369	Shared Neighborhood Hits	9
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

STAB2_HUMAN
NC score	0.007065 (rank : 39)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	534	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

VRK2_HUMAN
NC score	0.006925 (rank : 40)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	582	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y07, Q49AK9, Q53EU9, Q86Y08, Q86Y09, Q86Y10, Q86Y11, Q86Y12, Q8IXI5, Q99987	Gene names	VRK2
Domain Architecture
Description	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2).

DDX21_HUMAN
NC score	0.006595 (rank : 41)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	308	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

PRP4B_HUMAN
NC score	0.006512 (rank : 42)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	1030	Shared Neighborhood Hits	6
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

MYH14_MOUSE
NC score	0.005546 (rank : 43)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	1225	Shared Neighborhood Hits	7
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

M3K9_HUMAN
NC score	0.001763 (rank : 44)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	1123	Shared Neighborhood Hits	4
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).