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Network neighborhood for query Sequence : MBD1_MOUSE

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MBD1_MOUSE
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MBD1_HUMAN
θ value	0 (rank : 1)	NC score	0.980165 (rank : 2)
Query Neighborhood Hits	72	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

MBD1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

MBD2_MOUSE
θ value	1.24977e-17 (rank : 3)	NC score	0.543152 (rank : 3)
Query Neighborhood Hits	72	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2E1, Q811D9, Q9Z2D9	Gene names	Mbd2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2).

MBD2_HUMAN
θ value	3.63628e-17 (rank : 4)	NC score	0.539285 (rank : 4)
Query Neighborhood Hits	72	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBB5, O95242, Q9UIS8	Gene names	MBD2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) (Demethylase) (DMTase).

MBD3_HUMAN
θ value	6.41864e-14 (rank : 5)	NC score	0.515302 (rank : 6)
Query Neighborhood Hits	72	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	O95983, Q6PIL9, Q6PJZ9, Q86XF4	Gene names	MBD3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MBD3_MOUSE
θ value	6.41864e-14 (rank : 6)	NC score	0.515727 (rank : 5)
Query Neighborhood Hits	72	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2D8, Q792D3, Q8CFJ1	Gene names	Mbd3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

CXCC1_MOUSE
θ value	2.69671e-12 (rank : 7)	NC score	0.431709 (rank : 7)
Query Neighborhood Hits	72	Target Neighborhood Hits	124	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_HUMAN
θ value	6.00763e-12 (rank : 8)	NC score	0.427119 (rank : 8)
Query Neighborhood Hits	72	Target Neighborhood Hits	143	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

MLL4_HUMAN
θ value	6.64225e-11 (rank : 9)	NC score	0.258576 (rank : 21)
Query Neighborhood Hits	72	Target Neighborhood Hits	722	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

HRX_HUMAN
θ value	3.64472e-09 (rank : 10)	NC score	0.259978 (rank : 20)
Query Neighborhood Hits	72	Target Neighborhood Hits	825	Shared Neighborhood Hits	23
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

DNMT1_HUMAN
θ value	4.0297e-08 (rank : 11)	NC score	0.340340 (rank : 14)
Query Neighborhood Hits	72	Target Neighborhood Hits	401	Shared Neighborhood Hits	18
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

DNMT1_MOUSE
θ value	8.97725e-08 (rank : 12)	NC score	0.365170 (rank : 11)
Query Neighborhood Hits	72	Target Neighborhood Hits	137	Shared Neighborhood Hits	15
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

JHD1B_HUMAN
θ value	7.59969e-07 (rank : 13)	NC score	0.298689 (rank : 16)
Query Neighborhood Hits	72	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1B_MOUSE
θ value	7.59969e-07 (rank : 14)	NC score	0.299202 (rank : 15)
Query Neighborhood Hits	72	Target Neighborhood Hits	214	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

FXL19_HUMAN
θ value	4.92598e-06 (rank : 15)	NC score	0.354049 (rank : 12)
Query Neighborhood Hits	72	Target Neighborhood Hits	147	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_MOUSE
θ value	4.92598e-06 (rank : 16)	NC score	0.349753 (rank : 13)
Query Neighborhood Hits	72	Target Neighborhood Hits	217	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

MECP2_HUMAN
θ value	4.92598e-06 (rank : 17)	NC score	0.383825 (rank : 9)
Query Neighborhood Hits	72	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MECP2_MOUSE
θ value	4.92598e-06 (rank : 18)	NC score	0.378549 (rank : 10)
Query Neighborhood Hits	72	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

JHD1A_HUMAN
θ value	4.1701e-05 (rank : 19)	NC score	0.286691 (rank : 18)
Query Neighborhood Hits	72	Target Neighborhood Hits	133	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

JHD1A_MOUSE
θ value	4.1701e-05 (rank : 20)	NC score	0.287397 (rank : 17)
Query Neighborhood Hits	72	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

MBD4_MOUSE
θ value	0.00665767 (rank : 21)	NC score	0.262639 (rank : 19)
Query Neighborhood Hits	72	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2D7, Q792D2, Q8R3R3	Gene names	Mbd4
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase).

CXXC6_HUMAN
θ value	0.00869519 (rank : 22)	NC score	0.209014 (rank : 24)
Query Neighborhood Hits	72	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

MBD4_HUMAN
θ value	0.00869519 (rank : 23)	NC score	0.257895 (rank : 22)
Query Neighborhood Hits	72	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	O95243, Q7Z4T3, Q96F09	Gene names	MBD4, MED1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Methyl-CpG-binding endonuclease 1) (Mismatch-specific DNA N-glycosylase).

LAMB2_MOUSE
θ value	0.0330416 (rank : 24)	NC score	0.052156 (rank : 52)
Query Neighborhood Hits	72	Target Neighborhood Hits	722	Shared Neighborhood Hits	20
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LTBP4_MOUSE
θ value	0.0736092 (rank : 25)	NC score	0.024064 (rank : 75)
Query Neighborhood Hits	72	Target Neighborhood Hits	607	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

ZN202_HUMAN
θ value	0.163984 (rank : 26)	NC score	0.003049 (rank : 94)
Query Neighborhood Hits	72	Target Neighborhood Hits	756	Shared Neighborhood Hits	5
SwissProt Accessions	O95125, Q4JG21, Q9H1B9, Q9NSM4	Gene names	ZNF202
Domain Architecture
Description	Zinc finger protein 202.

ADAM2_HUMAN
θ value	0.21417 (rank : 27)	NC score	0.021021 (rank : 81)
Query Neighborhood Hits	72	Target Neighborhood Hits	175	Shared Neighborhood Hits	12
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

KRA54_HUMAN
θ value	0.279714 (rank : 28)	NC score	0.049245 (rank : 58)
Query Neighborhood Hits	72	Target Neighborhood Hits	270	Shared Neighborhood Hits	14
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LAMB2_HUMAN
θ value	0.279714 (rank : 29)	NC score	0.041730 (rank : 63)
Query Neighborhood Hits	72	Target Neighborhood Hits	692	Shared Neighborhood Hits	19
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

KRA59_HUMAN
θ value	0.365318 (rank : 30)	NC score	0.066976 (rank : 33)
Query Neighborhood Hits	72	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

MKL1_HUMAN
θ value	0.47712 (rank : 31)	NC score	0.030417 (rank : 72)
Query Neighborhood Hits	72	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

FHOD1_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.031881 (rank : 70)
Query Neighborhood Hits	72	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

ITB2_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.051129 (rank : 53)
Query Neighborhood Hits	72	Target Neighborhood Hits	282	Shared Neighborhood Hits	18
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB2_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.052618 (rank : 51)
Query Neighborhood Hits	72	Target Neighborhood Hits	326	Shared Neighborhood Hits	20
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

BSN_MOUSE
θ value	0.813845 (rank : 35)	NC score	0.033102 (rank : 67)
Query Neighborhood Hits	72	Target Neighborhood Hits	2057	Shared Neighborhood Hits	16
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ITB6_MOUSE
θ value	0.813845 (rank : 36)	NC score	0.051094 (rank : 54)
Query Neighborhood Hits	72	Target Neighborhood Hits	341	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

TAF4_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.030861 (rank : 71)
Query Neighborhood Hits	72	Target Neighborhood Hits	687	Shared Neighborhood Hits	8
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

VWF_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.032273 (rank : 69)
Query Neighborhood Hits	72	Target Neighborhood Hits	396	Shared Neighborhood Hits	16
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KRA51_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.044712 (rank : 59)
Query Neighborhood Hits	72	Target Neighborhood Hits	288	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

SRCH_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.055105 (rank : 45)
Query Neighborhood Hits	72	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

KR510_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.039572 (rank : 64)
Query Neighborhood Hits	72	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

VWF_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.030124 (rank : 73)
Query Neighborhood Hits	72	Target Neighborhood Hits	381	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ITB6_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.043335 (rank : 62)
Query Neighborhood Hits	72	Target Neighborhood Hits	318	Shared Neighborhood Hits	19
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

LAMB1_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.033364 (rank : 66)
Query Neighborhood Hits	72	Target Neighborhood Hits	1018	Shared Neighborhood Hits	21
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

NR6A1_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.013908 (rank : 86)
Query Neighborhood Hits	72	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR6A1_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.013893 (rank : 87)
Query Neighborhood Hits	72	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

ICK_HUMAN
θ value	3.0926 (rank : 47)	NC score	-0.000260 (rank : 97)
Query Neighborhood Hits	72	Target Neighborhood Hits	867	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPZ9, O75985, Q5THL2, Q8IYH8, Q9BX17, Q9NYX3	Gene names	ICK, KIAA0936
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2).

KR511_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.023820 (rank : 76)
Query Neighborhood Hits	72	Target Neighborhood Hits	231	Shared Neighborhood Hits	12
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

ODFP_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.028789 (rank : 74)
Query Neighborhood Hits	72	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q14990	Gene names	ODF1, ODFP
Domain Architecture
Description	Outer dense fiber protein.

PI3R5_MOUSE
θ value	3.0926 (rank : 50)	NC score	0.022130 (rank : 79)
Query Neighborhood Hits	72	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SW28, Q3TU01, Q3UDZ2, Q8C215, Q8CGQ7	Gene names	Pik3r5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit).

ITB1_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.043798 (rank : 61)
Query Neighborhood Hits	72	Target Neighborhood Hits	298	Shared Neighborhood Hits	24
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

NEIL3_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.023075 (rank : 77)
Query Neighborhood Hits	72	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

SPY1_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.017783 (rank : 84)
Query Neighborhood Hits	72	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

SYTL1_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.008589 (rank : 89)
Query Neighborhood Hits	72	Target Neighborhood Hits	314	Shared Neighborhood Hits	2
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

ZN750_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.022307 (rank : 78)
Query Neighborhood Hits	72	Target Neighborhood Hits	346	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ADAM2_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.018775 (rank : 82)
Query Neighborhood Hits	72	Target Neighborhood Hits	209	Shared Neighborhood Hits	17
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

BAZ2B_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.035064 (rank : 65)
Query Neighborhood Hits	72	Target Neighborhood Hits	803	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

ITB1_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.044199 (rank : 60)
Query Neighborhood Hits	72	Target Neighborhood Hits	283	Shared Neighborhood Hits	22
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

MAGI2_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.007854 (rank : 91)
Query Neighborhood Hits	72	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

SUHW4_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.004083 (rank : 92)
Query Neighborhood Hits	72	Target Neighborhood Hits	860	Shared Neighborhood Hits	6
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

ZMYM6_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.015506 (rank : 85)
Query Neighborhood Hits	72	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	O95789, Q96IY0	Gene names	ZMYM6, ZNF258
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 6 (Zinc finger protein 258).

BSN_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.021820 (rank : 80)
Query Neighborhood Hits	72	Target Neighborhood Hits	1537	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MOT1_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.008358 (rank : 90)
Query Neighborhood Hits	72	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P53986	Gene names	Slc16a1, Mct1
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1).

PHF3_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.050389 (rank : 56)
Query Neighborhood Hits	72	Target Neighborhood Hits	419	Shared Neighborhood Hits	7
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

TXK_HUMAN
θ value	6.88961 (rank : 65)	NC score	-0.001687 (rank : 99)
Query Neighborhood Hits	72	Target Neighborhood Hits	971	Shared Neighborhood Hits	4
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

AAK1_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.002347 (rank : 95)
Query Neighborhood Hits	72	Target Neighborhood Hits	1077	Shared Neighborhood Hits	10
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ABLM2_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.003578 (rank : 93)
Query Neighborhood Hits	72	Target Neighborhood Hits	317	Shared Neighborhood Hits	4
SwissProt Accessions	Q6H8Q1, Q6H8Q0, Q6NX73, Q8N3C5, Q8N9E9, Q8N9G2, Q96JL7	Gene names	ABLIM2, KIAA1808
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

ANLN_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.011542 (rank : 88)
Query Neighborhood Hits	72	Target Neighborhood Hits	297	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

KRA56_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.032982 (rank : 68)
Query Neighborhood Hits	72	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

PLAC8_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.018256 (rank : 83)
Query Neighborhood Hits	72	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI48	Gene names	Plac8
Domain Architecture
Description	Placenta-specific gene 8 protein (Protein C15) (Onzin).

ZN672_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.001369 (rank : 96)
Query Neighborhood Hits	72	Target Neighborhood Hits	744	Shared Neighborhood Hits	6
SwissProt Accessions	Q499Z4, Q96H65, Q96IM3, Q9H6G5	Gene names	ZNF672
Domain Architecture	No domain graphic available
Description	Zinc finger protein 672.

ZSCA2_MOUSE
θ value	8.99809 (rank : 72)	NC score	-0.000832 (rank : 98)
Query Neighborhood Hits	72	Target Neighborhood Hits	767	Shared Neighborhood Hits	7
SwissProt Accessions	Q07230	Gene names	Zscan2, Zfp-29, Zfp29
Domain Architecture
Description	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29) (Zfp-29).

FBXL2_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.050531 (rank : 55)
Query Neighborhood Hits	72	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

FBXL2_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.052780 (rank : 50)
Query Neighborhood Hits	72	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FBXL7_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.063160 (rank : 34)
Query Neighborhood Hits	72	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

FXL13_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.055121 (rank : 44)
Query Neighborhood Hits	72	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL14_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.053354 (rank : 48)
Query Neighborhood Hits	72	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.053505 (rank : 47)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL16_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.055974 (rank : 41)
Query Neighborhood Hits	72	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

FXL20_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.056876 (rank : 38)
Query Neighborhood Hits	72	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.056756 (rank : 39)
Query Neighborhood Hits	72	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

K1718_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.112765 (rank : 31)
Query Neighborhood Hits	72	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

K1718_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.115364 (rank : 27)
Query Neighborhood Hits	72	Target Neighborhood Hits	98	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

LRC29_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.058112 (rank : 36)
Query Neighborhood Hits	72	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

MB3L1_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.233401 (rank : 23)
Query Neighborhood Hits	72	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWY6	Gene names	MBD3L1, MBD3L
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1).

MB3L1_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.208757 (rank : 25)
Query Neighborhood Hits	72	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D9H3, Q6P8W5, Q9D2S3	Gene names	Mbd3l1, Mbd3l
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1).

MB3L2_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.193226 (rank : 26)
Query Neighborhood Hits	72	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHZ7	Gene names	MBD3L2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 2 (MBD3-like 2).

MLL3_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.053197 (rank : 49)
Query Neighborhood Hits	72	Target Neighborhood Hits	1644	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.055122 (rank : 43)
Query Neighborhood Hits	72	Target Neighborhood Hits	1399	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PHF11_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.056014 (rank : 40)
Query Neighborhood Hits	72	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF2_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.112214 (rank : 32)
Query Neighborhood Hits	72	Target Neighborhood Hits	208	Shared Neighborhood Hits	11
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.112916 (rank : 30)
Query Neighborhood Hits	72	Target Neighborhood Hits	241	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF8_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.114832 (rank : 28)
Query Neighborhood Hits	72	Target Neighborhood Hits	105	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF8_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.114181 (rank : 29)
Query Neighborhood Hits	72	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

SET1A_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.059118 (rank : 35)
Query Neighborhood Hits	72	Target Neighborhood Hits	690	Shared Neighborhood Hits	10
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETD8_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.054307 (rank : 46)
Query Neighborhood Hits	72	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.050306 (rank : 57)
Query Neighborhood Hits	72	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SKP2_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.057884 (rank : 37)
Query Neighborhood Hits	72	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

SKP2_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.055832 (rank : 42)
Query Neighborhood Hits	72	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

Hits sorted by NC score

MBD1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

MBD1_HUMAN
NC score	0.980165 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	72	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

MBD2_MOUSE
NC score	0.543152 (rank : 3)	θ value	1.24977e-17 (rank : 3)
Query Neighborhood Hits	72	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2E1, Q811D9, Q9Z2D9	Gene names	Mbd2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2).

MBD2_HUMAN
NC score	0.539285 (rank : 4)	θ value	3.63628e-17 (rank : 4)
Query Neighborhood Hits	72	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UBB5, O95242, Q9UIS8	Gene names	MBD2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) (Demethylase) (DMTase).

MBD3_MOUSE
NC score	0.515727 (rank : 5)	θ value	6.41864e-14 (rank : 6)
Query Neighborhood Hits	72	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2D8, Q792D3, Q8CFJ1	Gene names	Mbd3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

MBD3_HUMAN
NC score	0.515302 (rank : 6)	θ value	6.41864e-14 (rank : 5)
Query Neighborhood Hits	72	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	O95983, Q6PIL9, Q6PJZ9, Q86XF4	Gene names	MBD3
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3).

CXCC1_MOUSE
NC score	0.431709 (rank : 7)	θ value	2.69671e-12 (rank : 7)
Query Neighborhood Hits	72	Target Neighborhood Hits	124	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_HUMAN
NC score	0.427119 (rank : 8)	θ value	6.00763e-12 (rank : 8)
Query Neighborhood Hits	72	Target Neighborhood Hits	143	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

MECP2_HUMAN
NC score	0.383825 (rank : 9)	θ value	4.92598e-06 (rank : 17)
Query Neighborhood Hits	72	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MECP2_MOUSE
NC score	0.378549 (rank : 10)	θ value	4.92598e-06 (rank : 18)
Query Neighborhood Hits	72	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

DNMT1_MOUSE
NC score	0.365170 (rank : 11)	θ value	8.97725e-08 (rank : 12)
Query Neighborhood Hits	72	Target Neighborhood Hits	137	Shared Neighborhood Hits	15
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

FXL19_HUMAN
NC score	0.354049 (rank : 12)	θ value	4.92598e-06 (rank : 15)
Query Neighborhood Hits	72	Target Neighborhood Hits	147	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_MOUSE
NC score	0.349753 (rank : 13)	θ value	4.92598e-06 (rank : 16)
Query Neighborhood Hits	72	Target Neighborhood Hits	217	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

DNMT1_HUMAN
NC score	0.340340 (rank : 14)	θ value	4.0297e-08 (rank : 11)
Query Neighborhood Hits	72	Target Neighborhood Hits	401	Shared Neighborhood Hits	18
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

JHD1B_MOUSE
NC score	0.299202 (rank : 15)	θ value	7.59969e-07 (rank : 14)
Query Neighborhood Hits	72	Target Neighborhood Hits	214	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

JHD1B_HUMAN
NC score	0.298689 (rank : 16)	θ value	7.59969e-07 (rank : 13)
Query Neighborhood Hits	72	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1A_MOUSE
NC score	0.287397 (rank : 17)	θ value	4.1701e-05 (rank : 20)
Query Neighborhood Hits	72	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

JHD1A_HUMAN
NC score	0.286691 (rank : 18)	θ value	4.1701e-05 (rank : 19)
Query Neighborhood Hits	72	Target Neighborhood Hits	133	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

MBD4_MOUSE
NC score	0.262639 (rank : 19)	θ value	0.00665767 (rank : 21)
Query Neighborhood Hits	72	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2D7, Q792D2, Q8R3R3	Gene names	Mbd4
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase).

HRX_HUMAN
NC score	0.259978 (rank : 20)	θ value	3.64472e-09 (rank : 10)
Query Neighborhood Hits	72	Target Neighborhood Hits	825	Shared Neighborhood Hits	23
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL4_HUMAN
NC score	0.258576 (rank : 21)	θ value	6.64225e-11 (rank : 9)
Query Neighborhood Hits	72	Target Neighborhood Hits	722	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MBD4_HUMAN
NC score	0.257895 (rank : 22)	θ value	0.00869519 (rank : 23)
Query Neighborhood Hits	72	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	O95243, Q7Z4T3, Q96F09	Gene names	MBD4, MED1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Methyl-CpG-binding endonuclease 1) (Mismatch-specific DNA N-glycosylase).

MB3L1_HUMAN
NC score	0.233401 (rank : 23)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	72	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWY6	Gene names	MBD3L1, MBD3L
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1).

CXXC6_HUMAN
NC score	0.209014 (rank : 24)	θ value	0.00869519 (rank : 22)
Query Neighborhood Hits	72	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

MB3L1_MOUSE
NC score	0.208757 (rank : 25)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	72	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D9H3, Q6P8W5, Q9D2S3	Gene names	Mbd3l1, Mbd3l
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like 1).

MB3L2_HUMAN
NC score	0.193226 (rank : 26)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	72	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHZ7	Gene names	MBD3L2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 2 (MBD3-like 2).

K1718_MOUSE
NC score	0.115364 (rank : 27)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	72	Target Neighborhood Hits	98	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PHF8_HUMAN
NC score	0.114832 (rank : 28)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	72	Target Neighborhood Hits	105	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF8_MOUSE
NC score	0.114181 (rank : 29)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	72	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF2_MOUSE
NC score	0.112916 (rank : 30)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	72	Target Neighborhood Hits	241	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

K1718_HUMAN
NC score	0.112765 (rank : 31)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	72	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PHF2_HUMAN
NC score	0.112214 (rank : 32)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	72	Target Neighborhood Hits	208	Shared Neighborhood Hits	11
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

KRA59_HUMAN
NC score	0.066976 (rank : 33)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	72	Target Neighborhood Hits	310	Shared Neighborhood Hits	17
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

FBXL7_HUMAN
NC score	0.063160 (rank : 34)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	72	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

SET1A_HUMAN
NC score	0.059118 (rank : 35)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	72	Target Neighborhood Hits	690	Shared Neighborhood Hits	10
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

LRC29_HUMAN
NC score	0.058112 (rank : 36)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	72	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

SKP2_HUMAN
NC score	0.057884 (rank : 37)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	72	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

FXL20_HUMAN
NC score	0.056876 (rank : 38)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	72	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_MOUSE
NC score	0.056756 (rank : 39)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	72	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

PHF11_HUMAN
NC score	0.056014 (rank : 40)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	72	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

FXL16_HUMAN
NC score	0.055974 (rank : 41)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	72	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

SKP2_MOUSE
NC score	0.055832 (rank : 42)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	72	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

MLL3_MOUSE
NC score	0.055122 (rank : 43)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	72	Target Neighborhood Hits	1399	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

FXL13_MOUSE
NC score	0.055121 (rank : 44)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	72	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

SRCH_HUMAN
NC score	0.055105 (rank : 45)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	72	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

SETD8_HUMAN
NC score	0.054307 (rank : 46)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	72	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

FXL14_MOUSE
NC score	0.053505 (rank : 47)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_HUMAN
NC score	0.053354 (rank : 48)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	72	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

MLL3_HUMAN
NC score	0.053197 (rank : 49)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	72	Target Neighborhood Hits	1644	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

FBXL2_MOUSE
NC score	0.052780 (rank : 50)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	72	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

ITB2_MOUSE
NC score	0.052618 (rank : 51)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	72	Target Neighborhood Hits	326	Shared Neighborhood Hits	20
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

LAMB2_MOUSE
NC score	0.052156 (rank : 52)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	72	Target Neighborhood Hits	722	Shared Neighborhood Hits	20
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

ITB2_HUMAN
NC score	0.051129 (rank : 53)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	72	Target Neighborhood Hits	282	Shared Neighborhood Hits	18
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB6_MOUSE
NC score	0.051094 (rank : 54)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	72	Target Neighborhood Hits	341	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

FBXL2_HUMAN
NC score	0.050531 (rank : 55)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	72	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

PHF3_HUMAN
NC score	0.050389 (rank : 56)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	72	Target Neighborhood Hits	419	Shared Neighborhood Hits	7
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

SETD8_MOUSE
NC score	0.050306 (rank : 57)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	72	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

KRA54_HUMAN
NC score	0.049245 (rank : 58)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	72	Target Neighborhood Hits	270	Shared Neighborhood Hits	14
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA51_HUMAN
NC score	0.044712 (rank : 59)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	72	Target Neighborhood Hits	288	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

ITB1_MOUSE
NC score	0.044199 (rank : 60)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	72	Target Neighborhood Hits	283	Shared Neighborhood Hits	22
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_HUMAN
NC score	0.043798 (rank : 61)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	72	Target Neighborhood Hits	298	Shared Neighborhood Hits	24
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB6_HUMAN
NC score	0.043335 (rank : 62)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	72	Target Neighborhood Hits	318	Shared Neighborhood Hits	19
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

LAMB2_HUMAN
NC score	0.041730 (rank : 63)	θ value	0.279714 (rank : 29)
Query Neighborhood Hits	72	Target Neighborhood Hits	692	Shared Neighborhood Hits	19
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

KR510_HUMAN
NC score	0.039572 (rank : 64)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	72	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

BAZ2B_HUMAN
NC score	0.035064 (rank : 65)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	72	Target Neighborhood Hits	803	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

LAMB1_HUMAN
NC score	0.033364 (rank : 66)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	72	Target Neighborhood Hits	1018	Shared Neighborhood Hits	21
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

BSN_MOUSE
NC score	0.033102 (rank : 67)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	72	Target Neighborhood Hits	2057	Shared Neighborhood Hits	16
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

KRA56_HUMAN
NC score	0.032982 (rank : 68)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	72	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

VWF_HUMAN
NC score	0.032273 (rank : 69)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	72	Target Neighborhood Hits	396	Shared Neighborhood Hits	16
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

FHOD1_HUMAN
NC score	0.031881 (rank : 70)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	72	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

TAF4_HUMAN
NC score	0.030861 (rank : 71)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	72	Target Neighborhood Hits	687	Shared Neighborhood Hits	8
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

MKL1_HUMAN
NC score	0.030417 (rank : 72)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	72	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

VWF_MOUSE
NC score	0.030124 (rank : 73)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	72	Target Neighborhood Hits	381	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ODFP_HUMAN
NC score	0.028789 (rank : 74)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	72	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q14990	Gene names	ODF1, ODFP
Domain Architecture
Description	Outer dense fiber protein.

LTBP4_MOUSE
NC score	0.024064 (rank : 75)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	72	Target Neighborhood Hits	607	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

KR511_HUMAN
NC score	0.023820 (rank : 76)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	72	Target Neighborhood Hits	231	Shared Neighborhood Hits	12
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

NEIL3_HUMAN
NC score	0.023075 (rank : 77)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	72	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

ZN750_MOUSE
NC score	0.022307 (rank : 78)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	72	Target Neighborhood Hits	346	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

PI3R5_MOUSE
NC score	0.022130 (rank : 79)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	72	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SW28, Q3TU01, Q3UDZ2, Q8C215, Q8CGQ7	Gene names	Pik3r5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit).

BSN_HUMAN
NC score	0.021820 (rank : 80)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	72	Target Neighborhood Hits	1537	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

ADAM2_HUMAN
NC score	0.021021 (rank : 81)	θ value	0.21417 (rank : 27)
Query Neighborhood Hits	72	Target Neighborhood Hits	175	Shared Neighborhood Hits	12
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM2_MOUSE
NC score	0.018775 (rank : 82)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	72	Target Neighborhood Hits	209	Shared Neighborhood Hits	17
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

PLAC8_MOUSE
NC score	0.018256 (rank : 83)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	72	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI48	Gene names	Plac8
Domain Architecture
Description	Placenta-specific gene 8 protein (Protein C15) (Onzin).

SPY1_MOUSE
NC score	0.017783 (rank : 84)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	72	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

ZMYM6_HUMAN
NC score	0.015506 (rank : 85)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	72	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	O95789, Q96IY0	Gene names	ZMYM6, ZNF258
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 6 (Zinc finger protein 258).

NR6A1_HUMAN
NC score	0.013908 (rank : 86)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	72	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR6A1_MOUSE
NC score	0.013893 (rank : 87)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	72	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

ANLN_MOUSE
NC score	0.011542 (rank : 88)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	72	Target Neighborhood Hits	297	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

SYTL1_MOUSE
NC score	0.008589 (rank : 89)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	72	Target Neighborhood Hits	314	Shared Neighborhood Hits	2
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

MOT1_MOUSE
NC score	0.008358 (rank : 90)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	72	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P53986	Gene names	Slc16a1, Mct1
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1).

MAGI2_MOUSE
NC score	0.007854 (rank : 91)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	72	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

SUHW4_HUMAN
NC score	0.004083 (rank : 92)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	72	Target Neighborhood Hits	860	Shared Neighborhood Hits	6
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

ABLM2_HUMAN
NC score	0.003578 (rank : 93)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	72	Target Neighborhood Hits	317	Shared Neighborhood Hits	4
SwissProt Accessions	Q6H8Q1, Q6H8Q0, Q6NX73, Q8N3C5, Q8N9E9, Q8N9G2, Q96JL7	Gene names	ABLIM2, KIAA1808
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

ZN202_HUMAN
NC score	0.003049 (rank : 94)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	72	Target Neighborhood Hits	756	Shared Neighborhood Hits	5
SwissProt Accessions	O95125, Q4JG21, Q9H1B9, Q9NSM4	Gene names	ZNF202
Domain Architecture
Description	Zinc finger protein 202.

AAK1_HUMAN
NC score	0.002347 (rank : 95)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	72	Target Neighborhood Hits	1077	Shared Neighborhood Hits	10
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ZN672_HUMAN
NC score	0.001369 (rank : 96)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	72	Target Neighborhood Hits	744	Shared Neighborhood Hits	6
SwissProt Accessions	Q499Z4, Q96H65, Q96IM3, Q9H6G5	Gene names	ZNF672
Domain Architecture	No domain graphic available
Description	Zinc finger protein 672.

ICK_HUMAN
NC score	-0.000260 (rank : 97)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	72	Target Neighborhood Hits	867	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPZ9, O75985, Q5THL2, Q8IYH8, Q9BX17, Q9NYX3	Gene names	ICK, KIAA0936
Domain Architecture
Description	Serine/threonine-protein kinase ICK (EC 2.7.11.22) (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2).

ZSCA2_MOUSE
NC score	-0.000832 (rank : 98)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	72	Target Neighborhood Hits	767	Shared Neighborhood Hits	7
SwissProt Accessions	Q07230	Gene names	Zscan2, Zfp-29, Zfp29
Domain Architecture
Description	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29) (Zfp-29).

TXK_HUMAN
NC score	-0.001687 (rank : 99)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	72	Target Neighborhood Hits	971	Shared Neighborhood Hits	4
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).