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Network neighborhood for query Sequence : K1718_HUMAN

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K1718_HUMAN
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

K1718_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

K1718_MOUSE
θ value	0 (rank : 2)	NC score	0.991569 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	98	Shared Neighborhood Hits	57
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PHF8_MOUSE
θ value	2.48782e-175 (rank : 3)	NC score	0.969096 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	96	Shared Neighborhood Hits	45
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF8_HUMAN
θ value	2.32852e-173 (rank : 4)	NC score	0.966548 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF2_HUMAN
θ value	2.85304e-163 (rank : 5)	NC score	0.947579 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	208	Shared Neighborhood Hits	48
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_MOUSE
θ value	4.11978e-162 (rank : 6)	NC score	0.945595 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	241	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

JHD1B_HUMAN
θ value	1.60597e-73 (rank : 7)	NC score	0.763773 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	178	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1B_MOUSE
θ value	2.73936e-73 (rank : 8)	NC score	0.763494 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	214	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

JHD1A_HUMAN
θ value	1.90147e-66 (rank : 9)	NC score	0.772707 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	133	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

JHD1A_MOUSE
θ value	4.23606e-66 (rank : 10)	NC score	0.773515 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	134	Shared Neighborhood Hits	23
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

DIDO1_HUMAN
θ value	2.43908e-13 (rank : 11)	NC score	0.297907 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	960	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

BPTF_HUMAN
θ value	5.08577e-11 (rank : 12)	NC score	0.273164 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	786	Shared Neighborhood Hits	51
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CXCC1_HUMAN
θ value	4.30538e-10 (rank : 13)	NC score	0.495115 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	143	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
θ value	9.59137e-10 (rank : 14)	NC score	0.495770 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	124	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CN130_MOUSE
θ value	0.00020696 (rank : 15)	NC score	0.295896 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BU04, Q80UT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130 homolog.

JAD1A_HUMAN
θ value	0.00020696 (rank : 16)	NC score	0.172414 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	328	Shared Neighborhood Hits	53
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

CN130_HUMAN
θ value	0.00035302 (rank : 17)	NC score	0.293970 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N806, Q86U21, Q86UA9, Q96BY0, Q9NVV6	Gene names	C14orf130
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130.

PHF3_HUMAN
θ value	0.000602161 (rank : 18)	NC score	0.239056 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	419	Shared Neighborhood Hits	35
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PTDSR_MOUSE
θ value	0.00175202 (rank : 19)	NC score	0.275465 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERI5, Q80TX1	Gene names	Ptdsr, Kiaa0585
Domain Architecture	No domain graphic available
Description	Protein PTDSR (Phosphatidylserine receptor) (Apoptotic cell clearance receptor PtdSerR).

PTDSR_HUMAN
θ value	0.00298849 (rank : 20)	NC score	0.268190 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NYC1, Q86VY0, Q8IUM5, Q9Y4E2	Gene names	PTDSR, KIAA0585
Domain Architecture	No domain graphic available
Description	Protein PTDSR (Phosphatidylserine receptor).

TAF3_HUMAN
θ value	0.00298849 (rank : 21)	NC score	0.193980 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	568	Shared Neighborhood Hits	40
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

JAD1D_HUMAN
θ value	0.00390308 (rank : 22)	NC score	0.146006 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	147	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

SFRS4_HUMAN
θ value	0.00509761 (rank : 23)	NC score	0.031168 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	384	Shared Neighborhood Hits	11
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

TAF3_MOUSE
θ value	0.00665767 (rank : 24)	NC score	0.201609 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	463	Shared Neighborhood Hits	46
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

PKP4_MOUSE
θ value	0.0113563 (rank : 25)	NC score	0.030796 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

JAD1C_HUMAN
θ value	0.0148317 (rank : 26)	NC score	0.134528 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	187	Shared Neighborhood Hits	32
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	0.0148317 (rank : 27)	NC score	0.135272 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	164	Shared Neighborhood Hits	32
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

DSPP_HUMAN
θ value	0.0193708 (rank : 28)	NC score	0.036070 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	645	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PHF20_HUMAN
θ value	0.0193708 (rank : 29)	NC score	0.181324 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	394	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	0.0193708 (rank : 30)	NC score	0.174246 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	513	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

BRWD1_HUMAN
θ value	0.0252991 (rank : 31)	NC score	0.024142 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	448	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

GOGA5_MOUSE
θ value	0.0431538 (rank : 32)	NC score	0.014805 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	1434	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

MTF2_HUMAN
θ value	0.0431538 (rank : 33)	NC score	0.148187 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	119	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	0.0431538 (rank : 34)	NC score	0.147281 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	126	Shared Neighborhood Hits	27
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

TCF19_HUMAN
θ value	0.0431538 (rank : 35)	NC score	0.244325 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	124	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

ING3_HUMAN
θ value	0.0736092 (rank : 36)	NC score	0.146231 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

PHF13_HUMAN
θ value	0.0736092 (rank : 37)	NC score	0.216418 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	41	Shared Neighborhood Hits	22
SwissProt Accessions	Q86YI8, Q8N551, Q9UJP2	Gene names	PHF13
Domain Architecture
Description	PHD finger protein 13.

PHF13_MOUSE
θ value	0.0736092 (rank : 38)	NC score	0.217087 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K2W6	Gene names	Phf13
Domain Architecture
Description	PHD finger protein 13.

JAD1D_MOUSE
θ value	0.0961366 (rank : 39)	NC score	0.123206 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	228	Shared Neighborhood Hits	35
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

ING1_HUMAN
θ value	0.125558 (rank : 40)	NC score	0.158661 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING1_MOUSE
θ value	0.125558 (rank : 41)	NC score	0.156406 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

PHF1_HUMAN
θ value	0.125558 (rank : 42)	NC score	0.113646 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	117	Shared Neighborhood Hits	21
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	0.125558 (rank : 43)	NC score	0.113478 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	116	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

ING3_MOUSE
θ value	0.163984 (rank : 44)	NC score	0.134206 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

MPP8_HUMAN
θ value	0.47712 (rank : 45)	NC score	0.017737 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	948	Shared Neighborhood Hits	28
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NOP14_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.021875 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	324	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

ZF106_HUMAN
θ value	0.813845 (rank : 47)	NC score	0.022618 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	470	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

ZRAB2_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.054409 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

DDX46_MOUSE
θ value	1.06291 (rank : 49)	NC score	0.009936 (rank : 128)
Query Neighborhood Hits	114	Target Neighborhood Hits	358	Shared Neighborhood Hits	14
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

HPS5_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.020993 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	P59438	Gene names	Hps5, Ru2
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein homolog (Ruby-eye protein 2) (Ru2).

MLL4_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.129289 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	722	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MYH9_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.005485 (rank : 134)
Query Neighborhood Hits	114	Target Neighborhood Hits	1762	Shared Neighborhood Hits	35
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

LMO7_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.024029 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	507	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

RAD50_MOUSE
θ value	1.38821 (rank : 54)	NC score	0.010010 (rank : 127)
Query Neighborhood Hits	114	Target Neighborhood Hits	1366	Shared Neighborhood Hits	27
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

ING4_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.099962 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

ING4_MOUSE
θ value	1.81305 (rank : 56)	NC score	0.099049 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	93	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

MYST3_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.050043 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	772	Shared Neighborhood Hits	36
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

UTRO_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.011372 (rank : 116)
Query Neighborhood Hits	114	Target Neighborhood Hits	960	Shared Neighborhood Hits	19
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

WDR22_MOUSE
θ value	1.81305 (rank : 59)	NC score	0.013101 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	302	Shared Neighborhood Hits	5
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

BORIS_HUMAN
θ value	2.36792 (rank : 60)	NC score	-0.001354 (rank : 141)
Query Neighborhood Hits	114	Target Neighborhood Hits	743	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NI51, Q5JUG4, Q9BZ30, Q9NQJ3	Gene names	CTCFL, BORIS
Domain Architecture	No domain graphic available
Description	Transcriptional repressor CTCFL (CCCTC-binding factor) (Brother of the regulator of imprinted sites) (Zinc finger protein CTCF-T) (CTCF paralog).

CEP55_MOUSE
θ value	2.36792 (rank : 61)	NC score	0.012308 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	693	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

K1383_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.028502 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2G4, Q58EZ9, Q5VV83	Gene names	KIAA1383
Domain Architecture	No domain graphic available
Description	Protein KIAA1383.

MLL2_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.061473 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	1788	Shared Neighborhood Hits	47
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PININ_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.014997 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	753	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

RXINP_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.017941 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q5U5Q9, Q60811	Gene names	Rxrip110, Rip110
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110.

SMG7_MOUSE
θ value	2.36792 (rank : 66)	NC score	0.019557 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

CA103_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.016125 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CDD9, Q8C893	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf103 homolog.

DPOLZ_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.012848 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

EYA4_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.016475 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA4_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.016418 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

OSBL8_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.011529 (rank : 115)
Query Neighborhood Hits	114	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

A4_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.012690 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	274	Shared Neighborhood Hits	6
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

APLP1_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.014860 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	130	Shared Neighborhood Hits	10
SwissProt Accessions	Q03157, Q8VC38	Gene names	Aplp1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

CASC5_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.013669 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	376	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

CJ118_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.010560 (rank : 122)
Query Neighborhood Hits	114	Target Neighborhood Hits	937	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

DDX46_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.007897 (rank : 130)
Query Neighborhood Hits	114	Target Neighborhood Hits	357	Shared Neighborhood Hits	11
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

ETFD_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.027774 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q16134, Q7Z347	Gene names	ETFDH
Domain Architecture
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

EXOSX_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.013626 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q01780, Q15158	Gene names	EXOSC10, PMSCL, PMSCL2
Domain Architecture
Description	Exosome component 10 (Polymyositis/scleroderma autoantigen 2) (Autoantigen PM/Scl 2) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (P100 polymyositis-scleroderma overlap syndrome- associated autoantigen).

FANCM_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.012302 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

GP158_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.013146 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	221	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

ING2_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.119166 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	101	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

ING2_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.119471 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

LAP2_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.010558 (rank : 123)
Query Neighborhood Hits	114	Target Neighborhood Hits	499	Shared Neighborhood Hits	12
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

NEK11_HUMAN
θ value	4.03905 (rank : 84)	NC score	-0.003086 (rank : 144)
Query Neighborhood Hits	114	Target Neighborhood Hits	1043	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

PKP4_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.019856 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

RAI14_MOUSE
θ value	4.03905 (rank : 86)	NC score	0.005231 (rank : 136)
Query Neighborhood Hits	114	Target Neighborhood Hits	1505	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

DC12_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.013352 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q96FZ2, Q96G34, Q9NRP3	Gene names	C3orf37
Domain Architecture	No domain graphic available
Description	UPF0361 protein DC12.

EDEM1_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.014039 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q92611	Gene names	EDEM1, EDEM, KIAA0212
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 1.

EDEM1_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.011723 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q925U4	Gene names	Edem1, Edem
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 1.

HTSF1_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.013772 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	425	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

LAP2_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.009059 (rank : 129)
Query Neighborhood Hits	114	Target Neighborhood Hits	482	Shared Neighborhood Hits	11
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PDYN_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.013773 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P01213	Gene names	PDYN
Domain Architecture
Description	Beta-neoendorphin-dynorphin precursor (Proenkephalin B) (Preprodynorphin) [Contains: Beta-neoendorphin; Dynorphin; Leu- enkephalin; Rimorphin; Leumorphin].

R3HD1_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.011057 (rank : 118)
Query Neighborhood Hits	114	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

ANR12_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.014647 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	1081	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

BNC1_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.005648 (rank : 132)
Query Neighborhood Hits	114	Target Neighborhood Hits	460	Shared Neighborhood Hits	4
SwissProt Accessions	Q01954, Q15840	Gene names	BNC1, BNC
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-1.

CJ118_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.011344 (rank : 117)
Query Neighborhood Hits	114	Target Neighborhood Hits	1132	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CSF1_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.010039 (rank : 126)
Query Neighborhood Hits	114	Target Neighborhood Hits	258	Shared Neighborhood Hits	7
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

MINT_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.021903 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	1514	Shared Neighborhood Hits	31
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PLAL1_HUMAN
θ value	6.88961 (rank : 99)	NC score	-0.001920 (rank : 142)
Query Neighborhood Hits	114	Target Neighborhood Hits	728	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UM63	Gene names	PLAGL1
Domain Architecture	No domain graphic available
Description	Zinc finger protein PLAGL1 (Pleiomorphic adenoma-like protein 1).

ZDHC8_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.003996 (rank : 137)
Query Neighborhood Hits	114	Target Neighborhood Hits	243	Shared Neighborhood Hits	3
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

A4_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.010721 (rank : 121)
Query Neighborhood Hits	114	Target Neighborhood Hits	275	Shared Neighborhood Hits	6
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

AFF1_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.010757 (rank : 120)
Query Neighborhood Hits	114	Target Neighborhood Hits	506	Shared Neighborhood Hits	13
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ANKS6_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.002667 (rank : 139)
Query Neighborhood Hits	114	Target Neighborhood Hits	411	Shared Neighborhood Hits	5
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

CCD21_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.010096 (rank : 125)
Query Neighborhood Hits	114	Target Neighborhood Hits	1135	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CF146_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.010296 (rank : 124)
Query Neighborhood Hits	114	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9W6	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf146 homolog.

CYTSA_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.005553 (rank : 133)
Query Neighborhood Hits	114	Target Neighborhood Hits	1104	Shared Neighborhood Hits	22
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

ETFD_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.021930 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q921G7, Q3U7K2, Q8BK82, Q9DCT9	Gene names	Etfdh
Domain Architecture	No domain graphic available
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

FA21C_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.010763 (rank : 119)
Query Neighborhood Hits	114	Target Neighborhood Hits	194	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

FBX46_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.006803 (rank : 131)
Query Neighborhood Hits	114	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PJ61	Gene names	FBXO46, FBX46, FBXO34L
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

KI18A_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.002262 (rank : 140)
Query Neighborhood Hits	114	Target Neighborhood Hits	212	Shared Neighborhood Hits	10
SwissProt Accessions	Q91WD7, Q3TP77, Q8BLL1	Gene names	Kif18a
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

PP2CG_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.005433 (rank : 135)
Query Neighborhood Hits	114	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

RHG06_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.003540 (rank : 138)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

SMG7_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.015202 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q92540, Q5T1Q0, Q6PIE0, Q7Z7H9, Q8IXC1, Q8IXC2	Gene names	SMG7, C1orf16, EST1C, KIAA0250
Domain Architecture
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

TCF8_HUMAN
θ value	8.99809 (rank : 114)	NC score	-0.001934 (rank : 143)
Query Neighborhood Hits	114	Target Neighborhood Hits	1057	Shared Neighborhood Hits	14
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.052566 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	701	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.050446 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	394	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

CENPC_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.053204 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

CXXC6_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.053214 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	180	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

DNMT1_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.109064 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	401	Shared Neighborhood Hits	23
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

DNMT1_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.114921 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	8
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

FBX37_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.059111 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBXL2_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.080910 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

FBXL2_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.083801 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FBXL7_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.099679 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	91	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

FXL12_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.062786 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FXL12_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.069462 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FXL13_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.078006 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEE6, Q6UVW7, Q6UVW8, Q75MN5, Q86UJ5, Q8N7Y4, Q8TCL2, Q8WUF9, Q8WUG0	Gene names	FBXL13, FBL13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL13_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.088377 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL14_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.077572 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.077792 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL16_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.089816 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

FXL19_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.285503 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.280534 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL20_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.090381 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.089740 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

HRX_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.098830 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	825	Shared Neighborhood Hits	40
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ING5_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.056632 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING5_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.055706 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	76	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

INGX_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.054249 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P0U5	Gene names	INGX, ING2
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein, X-linked (Inhibitor of growth protein 2) (ING1-like tumor suppressor protein).

LRC29_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.084186 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

MBD1_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.118306 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

MBD1_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.112765 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	72	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

SKP2_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.099270 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

SKP2_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.088526 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

Hits sorted by NC score

K1718_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

K1718_MOUSE
NC score	0.991569 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	98	Shared Neighborhood Hits	57
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PHF8_MOUSE
NC score	0.969096 (rank : 3)	θ value	2.48782e-175 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	96	Shared Neighborhood Hits	45
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF8_HUMAN
NC score	0.966548 (rank : 4)	θ value	2.32852e-173 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF2_HUMAN
NC score	0.947579 (rank : 5)	θ value	2.85304e-163 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	208	Shared Neighborhood Hits	48
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_MOUSE
NC score	0.945595 (rank : 6)	θ value	4.11978e-162 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	241	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

JHD1A_MOUSE
NC score	0.773515 (rank : 7)	θ value	4.23606e-66 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	134	Shared Neighborhood Hits	23
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

JHD1A_HUMAN
NC score	0.772707 (rank : 8)	θ value	1.90147e-66 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	133	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

JHD1B_HUMAN
NC score	0.763773 (rank : 9)	θ value	1.60597e-73 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	178	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1B_MOUSE
NC score	0.763494 (rank : 10)	θ value	2.73936e-73 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	214	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

CXCC1_MOUSE
NC score	0.495770 (rank : 11)	θ value	9.59137e-10 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	124	Shared Neighborhood Hits	44
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_HUMAN
NC score	0.495115 (rank : 12)	θ value	4.30538e-10 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	143	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

DIDO1_HUMAN
NC score	0.297907 (rank : 13)	θ value	2.43908e-13 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	960	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

CN130_MOUSE
NC score	0.295896 (rank : 14)	θ value	0.00020696 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BU04, Q80UT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130 homolog.

CN130_HUMAN
NC score	0.293970 (rank : 15)	θ value	0.00035302 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N806, Q86U21, Q86UA9, Q96BY0, Q9NVV6	Gene names	C14orf130
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130.

FXL19_HUMAN
NC score	0.285503 (rank : 16)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	114	Target Neighborhood Hits	147	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_MOUSE
NC score	0.280534 (rank : 17)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	114	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

PTDSR_MOUSE
NC score	0.275465 (rank : 18)	θ value	0.00175202 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERI5, Q80TX1	Gene names	Ptdsr, Kiaa0585
Domain Architecture	No domain graphic available
Description	Protein PTDSR (Phosphatidylserine receptor) (Apoptotic cell clearance receptor PtdSerR).

BPTF_HUMAN
NC score	0.273164 (rank : 19)	θ value	5.08577e-11 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	786	Shared Neighborhood Hits	51
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

PTDSR_HUMAN
NC score	0.268190 (rank : 20)	θ value	0.00298849 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NYC1, Q86VY0, Q8IUM5, Q9Y4E2	Gene names	PTDSR, KIAA0585
Domain Architecture	No domain graphic available
Description	Protein PTDSR (Phosphatidylserine receptor).

TCF19_HUMAN
NC score	0.244325 (rank : 21)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	124	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

PHF3_HUMAN
NC score	0.239056 (rank : 22)	θ value	0.000602161 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	419	Shared Neighborhood Hits	35
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PHF13_MOUSE
NC score	0.217087 (rank : 23)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K2W6	Gene names	Phf13
Domain Architecture
Description	PHD finger protein 13.

PHF13_HUMAN
NC score	0.216418 (rank : 24)	θ value	0.0736092 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	41	Shared Neighborhood Hits	22
SwissProt Accessions	Q86YI8, Q8N551, Q9UJP2	Gene names	PHF13
Domain Architecture
Description	PHD finger protein 13.

TAF3_MOUSE
NC score	0.201609 (rank : 25)	θ value	0.00665767 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	463	Shared Neighborhood Hits	46
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_HUMAN
NC score	0.193980 (rank : 26)	θ value	0.00298849 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	568	Shared Neighborhood Hits	40
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

PHF20_HUMAN
NC score	0.181324 (rank : 27)	θ value	0.0193708 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	394	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
NC score	0.174246 (rank : 28)	θ value	0.0193708 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	513	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

JAD1A_HUMAN
NC score	0.172414 (rank : 29)	θ value	0.00020696 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	328	Shared Neighborhood Hits	53
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

ING1_HUMAN
NC score	0.158661 (rank : 30)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING1_MOUSE
NC score	0.156406 (rank : 31)	θ value	0.125558 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	71	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

MTF2_HUMAN
NC score	0.148187 (rank : 32)	θ value	0.0431538 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	119	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
NC score	0.147281 (rank : 33)	θ value	0.0431538 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	126	Shared Neighborhood Hits	27
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

ING3_HUMAN
NC score	0.146231 (rank : 34)	θ value	0.0736092 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	178	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

JAD1D_HUMAN
NC score	0.146006 (rank : 35)	θ value	0.00390308 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	147	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1C_MOUSE
NC score	0.135272 (rank : 36)	θ value	0.0148317 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	164	Shared Neighborhood Hits	32
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1C_HUMAN
NC score	0.134528 (rank : 37)	θ value	0.0148317 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	187	Shared Neighborhood Hits	32
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

ING3_MOUSE
NC score	0.134206 (rank : 38)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	177	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

MLL4_HUMAN
NC score	0.129289 (rank : 39)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	722	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

JAD1D_MOUSE
NC score	0.123206 (rank : 40)	θ value	0.0961366 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	228	Shared Neighborhood Hits	35
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

ING2_MOUSE
NC score	0.119471 (rank : 41)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

ING2_HUMAN
NC score	0.119166 (rank : 42)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	101	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

MBD1_HUMAN
NC score	0.118306 (rank : 43)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	114	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

DNMT1_MOUSE
NC score	0.114921 (rank : 44)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	8
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

PHF1_HUMAN
NC score	0.113646 (rank : 45)	θ value	0.125558 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	117	Shared Neighborhood Hits	21
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
NC score	0.113478 (rank : 46)	θ value	0.125558 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	116	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

MBD1_MOUSE
NC score	0.112765 (rank : 47)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	114	Target Neighborhood Hits	72	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

DNMT1_HUMAN
NC score	0.109064 (rank : 48)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	114	Target Neighborhood Hits	401	Shared Neighborhood Hits	23
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

ING4_HUMAN
NC score	0.099962 (rank : 49)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

FBXL7_HUMAN
NC score	0.099679 (rank : 50)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	114	Target Neighborhood Hits	91	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

SKP2_HUMAN
NC score	0.099270 (rank : 51)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	114	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

ING4_MOUSE
NC score	0.099049 (rank : 52)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	93	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

HRX_HUMAN
NC score	0.098830 (rank : 53)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	114	Target Neighborhood Hits	825	Shared Neighborhood Hits	40
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

FXL20_HUMAN
NC score	0.090381 (rank : 54)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	114	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL16_HUMAN
NC score	0.089816 (rank : 55)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	114	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

FXL20_MOUSE
NC score	0.089740 (rank : 56)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	114	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

SKP2_MOUSE
NC score	0.088526 (rank : 57)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

FXL13_MOUSE
NC score	0.088377 (rank : 58)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	114	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

LRC29_HUMAN
NC score	0.084186 (rank : 59)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

FBXL2_MOUSE
NC score	0.083801 (rank : 60)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	114	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FBXL2_HUMAN
NC score	0.080910 (rank : 61)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	114	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

FXL13_HUMAN
NC score	0.078006 (rank : 62)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	114	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEE6, Q6UVW7, Q6UVW8, Q75MN5, Q86UJ5, Q8N7Y4, Q8TCL2, Q8WUF9, Q8WUG0	Gene names	FBXL13, FBL13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL14_MOUSE
NC score	0.077792 (rank : 63)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	114	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_HUMAN
NC score	0.077572 (rank : 64)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	114	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL12_MOUSE
NC score	0.069462 (rank : 65)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	114	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPX5, Q3UVH7, Q8CDX0, Q9CY04, Q9QZN5	Gene names	Fbxl12, Fbl12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

FXL12_HUMAN
NC score	0.062786 (rank : 66)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	114	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NXK8, Q9H5K4	Gene names	FBXL12, FBL12
Domain Architecture
Description	F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12).

MLL2_HUMAN
NC score	0.061473 (rank : 67)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	1788	Shared Neighborhood Hits	47
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

FBX37_HUMAN
NC score	0.059111 (rank : 68)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	114	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

ING5_HUMAN
NC score	0.056632 (rank : 69)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	114	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING5_MOUSE
NC score	0.055706 (rank : 70)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	114	Target Neighborhood Hits	76	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

ZRAB2_HUMAN
NC score	0.054409 (rank : 71)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

INGX_HUMAN
NC score	0.054249 (rank : 72)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P0U5	Gene names	INGX, ING2
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein, X-linked (Inhibitor of growth protein 2) (ING1-like tumor suppressor protein).

CXXC6_HUMAN
NC score	0.053214 (rank : 73)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	114	Target Neighborhood Hits	180	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

CENPC_MOUSE
NC score	0.053204 (rank : 74)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	114	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

BAZ1B_HUMAN
NC score	0.052566 (rank : 75)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	114	Target Neighborhood Hits	701	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
NC score	0.050446 (rank : 76)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	114	Target Neighborhood Hits	394	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

MYST3_HUMAN
NC score	0.050043 (rank : 77)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	772	Shared Neighborhood Hits	36
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

DSPP_HUMAN
NC score	0.036070 (rank : 78)	θ value	0.0193708 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	645	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SFRS4_HUMAN
NC score	0.031168 (rank : 79)	θ value	0.00509761 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	384	Shared Neighborhood Hits	11
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

PKP4_MOUSE
NC score	0.030796 (rank : 80)	θ value	0.0113563 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

K1383_HUMAN
NC score	0.028502 (rank : 81)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2G4, Q58EZ9, Q5VV83	Gene names	KIAA1383
Domain Architecture	No domain graphic available
Description	Protein KIAA1383.

ETFD_HUMAN
NC score	0.027774 (rank : 82)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q16134, Q7Z347	Gene names	ETFDH
Domain Architecture
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

BRWD1_HUMAN
NC score	0.024142 (rank : 83)	θ value	0.0252991 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	448	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

LMO7_HUMAN
NC score	0.024029 (rank : 84)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	507	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

ZF106_HUMAN
NC score	0.022618 (rank : 85)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	470	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

ETFD_MOUSE
NC score	0.021930 (rank : 86)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q921G7, Q3U7K2, Q8BK82, Q9DCT9	Gene names	Etfdh
Domain Architecture	No domain graphic available
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

MINT_MOUSE
NC score	0.021903 (rank : 87)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	1514	Shared Neighborhood Hits	31
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NOP14_MOUSE
NC score	0.021875 (rank : 88)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	324	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

HPS5_MOUSE
NC score	0.020993 (rank : 89)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	P59438	Gene names	Hps5, Ru2
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 5 protein homolog (Ruby-eye protein 2) (Ru2).

PKP4_HUMAN
NC score	0.019856 (rank : 90)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

SMG7_MOUSE
NC score	0.019557 (rank : 91)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q5RJH6, Q63ZW5, Q6ZQF3	Gene names	Smg7, Est1c, Kiaa0250
Domain Architecture	No domain graphic available
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

RXINP_MOUSE
NC score	0.017941 (rank : 92)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q5U5Q9, Q60811	Gene names	Rxrip110, Rip110
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110.

MPP8_HUMAN
NC score	0.017737 (rank : 93)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	948	Shared Neighborhood Hits	28
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

EYA4_HUMAN
NC score	0.016475 (rank : 94)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA4_MOUSE
NC score	0.016418 (rank : 95)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

CA103_MOUSE
NC score	0.016125 (rank : 96)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CDD9, Q8C893	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf103 homolog.

SMG7_HUMAN
NC score	0.015202 (rank : 97)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q92540, Q5T1Q0, Q6PIE0, Q7Z7H9, Q8IXC1, Q8IXC2	Gene names	SMG7, C1orf16, EST1C, KIAA0250
Domain Architecture
Description	Protein SMG7 (SMG-7 homolog) (EST1-like protein C).

PININ_HUMAN
NC score	0.014997 (rank : 98)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	753	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

APLP1_MOUSE
NC score	0.014860 (rank : 99)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	130	Shared Neighborhood Hits	10
SwissProt Accessions	Q03157, Q8VC38	Gene names	Aplp1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

GOGA5_MOUSE
NC score	0.014805 (rank : 100)	θ value	0.0431538 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	1434	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

ANR12_HUMAN
NC score	0.014647 (rank : 101)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	1081	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

EDEM1_HUMAN
NC score	0.014039 (rank : 102)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q92611	Gene names	EDEM1, EDEM, KIAA0212
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 1.

PDYN_HUMAN
NC score	0.013773 (rank : 103)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P01213	Gene names	PDYN
Domain Architecture
Description	Beta-neoendorphin-dynorphin precursor (Proenkephalin B) (Preprodynorphin) [Contains: Beta-neoendorphin; Dynorphin; Leu- enkephalin; Rimorphin; Leumorphin].

HTSF1_MOUSE
NC score	0.013772 (rank : 104)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	425	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

CASC5_HUMAN
NC score	0.013669 (rank : 105)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	376	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

EXOSX_HUMAN
NC score	0.013626 (rank : 106)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q01780, Q15158	Gene names	EXOSC10, PMSCL, PMSCL2
Domain Architecture
Description	Exosome component 10 (Polymyositis/scleroderma autoantigen 2) (Autoantigen PM/Scl 2) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (P100 polymyositis-scleroderma overlap syndrome- associated autoantigen).

DC12_HUMAN
NC score	0.013352 (rank : 107)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q96FZ2, Q96G34, Q9NRP3	Gene names	C3orf37
Domain Architecture	No domain graphic available
Description	UPF0361 protein DC12.

GP158_HUMAN
NC score	0.013146 (rank : 108)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	221	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

WDR22_MOUSE
NC score	0.013101 (rank : 109)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	302	Shared Neighborhood Hits	5
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

DPOLZ_HUMAN
NC score	0.012848 (rank : 110)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

A4_HUMAN
NC score	0.012690 (rank : 111)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	274	Shared Neighborhood Hits	6
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

CEP55_MOUSE
NC score	0.012308 (rank : 112)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	693	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

FANCM_MOUSE
NC score	0.012302 (rank : 113)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

EDEM1_MOUSE
NC score	0.011723 (rank : 114)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q925U4	Gene names	Edem1, Edem
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 1.

OSBL8_HUMAN
NC score	0.011529 (rank : 115)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

UTRO_HUMAN
NC score	0.011372 (rank : 116)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	960	Shared Neighborhood Hits	19
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

CJ118_MOUSE
NC score	0.011344 (rank : 117)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	1132	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

R3HD1_HUMAN
NC score	0.011057 (rank : 118)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

FA21C_HUMAN
NC score	0.010763 (rank : 119)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	194	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

AFF1_HUMAN
NC score	0.010757 (rank : 120)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	506	Shared Neighborhood Hits	13
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

A4_MOUSE
NC score	0.010721 (rank : 121)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	275	Shared Neighborhood Hits	6
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

CJ118_HUMAN
NC score	0.010560 (rank : 122)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	937	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

LAP2_HUMAN
NC score	0.010558 (rank : 123)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	499	Shared Neighborhood Hits	12
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

CF146_MOUSE
NC score	0.010296 (rank : 124)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9W6	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf146 homolog.

CCD21_MOUSE
NC score	0.010096 (rank : 125)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	1135	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CSF1_HUMAN
NC score	0.010039 (rank : 126)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	258	Shared Neighborhood Hits	7
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

RAD50_MOUSE
NC score	0.010010 (rank : 127)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	1366	Shared Neighborhood Hits	27
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

DDX46_MOUSE
NC score	0.009936 (rank : 128)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	358	Shared Neighborhood Hits	14
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

LAP2_MOUSE
NC score	0.009059 (rank : 129)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	482	Shared Neighborhood Hits	11
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

DDX46_HUMAN
NC score	0.007897 (rank : 130)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	357	Shared Neighborhood Hits	11
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

FBX46_HUMAN
NC score	0.006803 (rank : 131)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PJ61	Gene names	FBXO46, FBX46, FBXO34L
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

BNC1_HUMAN
NC score	0.005648 (rank : 132)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	460	Shared Neighborhood Hits	4
SwissProt Accessions	Q01954, Q15840	Gene names	BNC1, BNC
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-1.

CYTSA_MOUSE
NC score	0.005553 (rank : 133)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	1104	Shared Neighborhood Hits	22
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

MYH9_HUMAN
NC score	0.005485 (rank : 134)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	1762	Shared Neighborhood Hits	35
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PP2CG_MOUSE
NC score	0.005433 (rank : 135)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

RAI14_MOUSE
NC score	0.005231 (rank : 136)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	1505	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ZDHC8_MOUSE
NC score	0.003996 (rank : 137)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	243	Shared Neighborhood Hits	3
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

RHG06_HUMAN
NC score	0.003540 (rank : 138)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

ANKS6_HUMAN
NC score	0.002667 (rank : 139)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	411	Shared Neighborhood Hits	5
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

KI18A_MOUSE
NC score	0.002262 (rank : 140)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	212	Shared Neighborhood Hits	10
SwissProt Accessions	Q91WD7, Q3TP77, Q8BLL1	Gene names	Kif18a
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

BORIS_HUMAN
NC score	-0.001354 (rank : 141)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	743	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NI51, Q5JUG4, Q9BZ30, Q9NQJ3	Gene names	CTCFL, BORIS
Domain Architecture	No domain graphic available
Description	Transcriptional repressor CTCFL (CCCTC-binding factor) (Brother of the regulator of imprinted sites) (Zinc finger protein CTCF-T) (CTCF paralog).

PLAL1_HUMAN
NC score	-0.001920 (rank : 142)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	728	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UM63	Gene names	PLAGL1
Domain Architecture	No domain graphic available
Description	Zinc finger protein PLAGL1 (Pleiomorphic adenoma-like protein 1).

TCF8_HUMAN
NC score	-0.001934 (rank : 143)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	1057	Shared Neighborhood Hits	14
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

NEK11_HUMAN
NC score	-0.003086 (rank : 144)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	1043	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).