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Network neighborhood for query Sequence : ETFD_HUMAN

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ETFD_HUMAN
SwissProt Accessions	Q16134, Q7Z347	Gene names	ETFDH
Domain Architecture
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ETFD_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q16134, Q7Z347	Gene names	ETFDH
Domain Architecture
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

ETFD_MOUSE
θ value	0 (rank : 2)	NC score	0.998245 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q921G7, Q3U7K2, Q8BK82, Q9DCT9	Gene names	Etfdh
Domain Architecture	No domain graphic available
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

DLDH_MOUSE
θ value	0.279714 (rank : 3)	NC score	0.087165 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	O08749	Gene names	Dld
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase).

M4K1_HUMAN
θ value	0.365318 (rank : 4)	NC score	0.013291 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	884	Shared Neighborhood Hits	4
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

DLDH_HUMAN
θ value	0.47712 (rank : 5)	NC score	0.082785 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	P09622, Q14131, Q14167	Gene names	DLD, GCSL, LAD, PHE3
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein).

MICA1_MOUSE
θ value	0.62314 (rank : 6)	NC score	0.047387 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	400	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

AOF1_HUMAN
θ value	1.06291 (rank : 7)	NC score	0.059880 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

MICA1_HUMAN
θ value	1.06291 (rank : 8)	NC score	0.044806 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	279	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

K1718_MOUSE
θ value	1.81305 (rank : 9)	NC score	0.033249 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PAOX_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.039651 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

DYXC1_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.034802 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

AOF1_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.044283 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

K1718_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.027774 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

NNTM_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.035496 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q61941, Q9JK70	Gene names	Nnt
Domain Architecture
Description	NAD(P) transhydrogenase, mitochondrial precursor (EC 1.6.1.2) (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase).

AOFB_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.020963 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	38	Shared Neighborhood Hits	6
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

GSHR_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.029980 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P00390, Q7Z5C9, Q9NP63	Gene names	GSR, GLUR, GRD1
Domain Architecture
Description	Glutathione reductase, mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).

NNTM_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.033954 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q13423, Q16796, Q8N3V4	Gene names	NNT
Domain Architecture
Description	NAD(P) transhydrogenase, mitochondrial precursor (EC 1.6.1.2) (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase).

PAOX_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.032602 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

SDHL_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.030668 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBT2	Gene names	Sds
Domain Architecture	No domain graphic available
Description	L-serine dehydratase (EC 4.3.1.17) (L-serine deaminase).

Hits sorted by NC score

ETFD_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q16134, Q7Z347	Gene names	ETFDH
Domain Architecture
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

ETFD_MOUSE
NC score	0.998245 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	Q921G7, Q3U7K2, Q8BK82, Q9DCT9	Gene names	Etfdh
Domain Architecture	No domain graphic available
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

DLDH_MOUSE
NC score	0.087165 (rank : 3)	θ value	0.279714 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	O08749	Gene names	Dld
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase).

DLDH_HUMAN
NC score	0.082785 (rank : 4)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	P09622, Q14131, Q14167	Gene names	DLD, GCSL, LAD, PHE3
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein).

AOF1_HUMAN
NC score	0.059880 (rank : 5)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

MICA1_MOUSE
NC score	0.047387 (rank : 6)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	400	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MICA1_HUMAN
NC score	0.044806 (rank : 7)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	279	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

AOF1_MOUSE
NC score	0.044283 (rank : 8)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

PAOX_MOUSE
NC score	0.039651 (rank : 9)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

NNTM_MOUSE
NC score	0.035496 (rank : 10)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q61941, Q9JK70	Gene names	Nnt
Domain Architecture
Description	NAD(P) transhydrogenase, mitochondrial precursor (EC 1.6.1.2) (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase).

DYXC1_HUMAN
NC score	0.034802 (rank : 11)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

NNTM_HUMAN
NC score	0.033954 (rank : 12)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q13423, Q16796, Q8N3V4	Gene names	NNT
Domain Architecture
Description	NAD(P) transhydrogenase, mitochondrial precursor (EC 1.6.1.2) (Pyridine nucleotide transhydrogenase) (Nicotinamide nucleotide transhydrogenase).

K1718_MOUSE
NC score	0.033249 (rank : 13)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PAOX_HUMAN
NC score	0.032602 (rank : 14)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

SDHL_MOUSE
NC score	0.030668 (rank : 15)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBT2	Gene names	Sds
Domain Architecture	No domain graphic available
Description	L-serine dehydratase (EC 4.3.1.17) (L-serine deaminase).

GSHR_HUMAN
NC score	0.029980 (rank : 16)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P00390, Q7Z5C9, Q9NP63	Gene names	GSR, GLUR, GRD1
Domain Architecture
Description	Glutathione reductase, mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).

K1718_HUMAN
NC score	0.027774 (rank : 17)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

AOFB_HUMAN
NC score	0.020963 (rank : 18)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	38	Shared Neighborhood Hits	6
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

M4K1_HUMAN
NC score	0.013291 (rank : 19)	θ value	0.365318 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	884	Shared Neighborhood Hits	4
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).