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Network neighborhood for query Sequence : PAOX_HUMAN

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PAOX_HUMAN
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PAOX_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

PAOX_MOUSE
θ value	0 (rank : 2)	NC score	0.992487 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

SMOX_MOUSE
θ value	4.80189e-94 (rank : 3)	NC score	0.942853 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

SMOX_HUMAN
θ value	1.39714e-93 (rank : 4)	NC score	0.943060 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

LSD1_HUMAN
θ value	6.18819e-25 (rank : 5)	NC score	0.676472 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	455	Shared Neighborhood Hits	15
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_MOUSE
θ value	6.18819e-25 (rank : 6)	NC score	0.707791 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	224	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

AOF1_HUMAN
θ value	3.07116e-24 (rank : 7)	NC score	0.720134 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOF1_MOUSE
θ value	3.07116e-24 (rank : 8)	NC score	0.721091 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOFB_HUMAN
θ value	4.45536e-07 (rank : 9)	NC score	0.397604 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFB_MOUSE
θ value	0.00134147 (rank : 10)	NC score	0.351921 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BW75, Q8C0B2	Gene names	Maob
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

PPOX_HUMAN
θ value	0.00509761 (rank : 11)	NC score	0.221378 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

OXLA_HUMAN
θ value	0.00665767 (rank : 12)	NC score	0.275961 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

AOFA_HUMAN
θ value	0.0113563 (rank : 13)	NC score	0.317089 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	P21397, Q16426	Gene names	MAOA
Domain Architecture
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

PPOX_MOUSE
θ value	0.0113563 (rank : 14)	NC score	0.192091 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	P51175, P97344, Q99M34	Gene names	Ppox
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

AOFA_MOUSE
θ value	0.0148317 (rank : 15)	NC score	0.333806 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

OXLA_MOUSE
θ value	0.0252991 (rank : 16)	NC score	0.289788 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

LRC50_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.009218 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	275	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

ADRO_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.025334 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q61578	Gene names	Fdxr
Domain Architecture
Description	NADPH:adrenodoxin oxidoreductase, mitochondrial precursor (EC 1.18.1.2) (Adrenodoxin reductase) (AR) (Ferredoxin reductase) (Ferredoxin--NADP(+) reductase).

ETFD_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.032602 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q16134, Q7Z347	Gene names	ETFDH
Domain Architecture
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

NRK_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.000608 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	931	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

UCP1_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.004589 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	P25874, Q13218, Q4KMZ3, Q68G66	Gene names	UCP1, SLC25A7, UCP
Domain Architecture
Description	Mitochondrial brown fat uncoupling protein 1 (UCP 1) (Thermogenin).

Hits sorted by NC score

PAOX_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

PAOX_MOUSE
NC score	0.992487 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

SMOX_HUMAN
NC score	0.943060 (rank : 3)	θ value	1.39714e-93 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

SMOX_MOUSE
NC score	0.942853 (rank : 4)	θ value	4.80189e-94 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

AOF1_MOUSE
NC score	0.721091 (rank : 5)	θ value	3.07116e-24 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOF1_HUMAN
NC score	0.720134 (rank : 6)	θ value	3.07116e-24 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

LSD1_MOUSE
NC score	0.707791 (rank : 7)	θ value	6.18819e-25 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	224	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_HUMAN
NC score	0.676472 (rank : 8)	θ value	6.18819e-25 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	455	Shared Neighborhood Hits	15
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

AOFB_HUMAN
NC score	0.397604 (rank : 9)	θ value	4.45536e-07 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFB_MOUSE
NC score	0.351921 (rank : 10)	θ value	0.00134147 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BW75, Q8C0B2	Gene names	Maob
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFA_MOUSE
NC score	0.333806 (rank : 11)	θ value	0.0148317 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFA_HUMAN
NC score	0.317089 (rank : 12)	θ value	0.0113563 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	P21397, Q16426	Gene names	MAOA
Domain Architecture
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

OXLA_MOUSE
NC score	0.289788 (rank : 13)	θ value	0.0252991 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

OXLA_HUMAN
NC score	0.275961 (rank : 14)	θ value	0.00665767 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

PPOX_HUMAN
NC score	0.221378 (rank : 15)	θ value	0.00509761 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

PPOX_MOUSE
NC score	0.192091 (rank : 16)	θ value	0.0113563 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	P51175, P97344, Q99M34	Gene names	Ppox
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

ETFD_HUMAN
NC score	0.032602 (rank : 17)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q16134, Q7Z347	Gene names	ETFDH
Domain Architecture
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

ADRO_MOUSE
NC score	0.025334 (rank : 18)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q61578	Gene names	Fdxr
Domain Architecture
Description	NADPH:adrenodoxin oxidoreductase, mitochondrial precursor (EC 1.18.1.2) (Adrenodoxin reductase) (AR) (Ferredoxin reductase) (Ferredoxin--NADP(+) reductase).

LRC50_HUMAN
NC score	0.009218 (rank : 19)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	275	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

UCP1_HUMAN
NC score	0.004589 (rank : 20)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	P25874, Q13218, Q4KMZ3, Q68G66	Gene names	UCP1, SLC25A7, UCP
Domain Architecture
Description	Mitochondrial brown fat uncoupling protein 1 (UCP 1) (Thermogenin).

NRK_HUMAN
NC score	0.000608 (rank : 21)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	931	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).