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Network neighborhood for query Sequence : SMOX_HUMAN

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SMOX_HUMAN
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMOX_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

SMOX_MOUSE
θ value	0 (rank : 2)	NC score	0.998287 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	34	Shared Neighborhood Hits	29
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

PAOX_MOUSE
θ value	4.95767e-99 (rank : 3)	NC score	0.944908 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

PAOX_HUMAN
θ value	1.39714e-93 (rank : 4)	NC score	0.943060 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

LSD1_HUMAN
θ value	1.85889e-29 (rank : 5)	NC score	0.691559 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	455	Shared Neighborhood Hits	23
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_MOUSE
θ value	1.85889e-29 (rank : 6)	NC score	0.723499 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	224	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

AOF1_HUMAN
θ value	1.02001e-27 (rank : 7)	NC score	0.729835 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOF1_MOUSE
θ value	5.06226e-27 (rank : 8)	NC score	0.727882 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOFB_HUMAN
θ value	9.29e-05 (rank : 9)	NC score	0.379903 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFA_MOUSE
θ value	0.00020696 (rank : 10)	NC score	0.330025 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFA_HUMAN
θ value	0.00390308 (rank : 11)	NC score	0.308823 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	21
SwissProt Accessions	P21397, Q16426	Gene names	MAOA
Domain Architecture
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFB_MOUSE
θ value	0.00869519 (rank : 12)	NC score	0.332578 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BW75, Q8C0B2	Gene names	Maob
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

OXLA_HUMAN
θ value	0.0330416 (rank : 13)	NC score	0.257739 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

FMO1_MOUSE
θ value	0.0431538 (rank : 14)	NC score	0.107094 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	18	Shared Neighborhood Hits	17
SwissProt Accessions	P50285	Gene names	Fmo1, Fmo-1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO1_HUMAN
θ value	0.125558 (rank : 15)	NC score	0.110776 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	21
SwissProt Accessions	Q01740, Q5QPT2, Q9UJC2	Gene names	FMO1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Fetal hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO3_MOUSE
θ value	0.125558 (rank : 16)	NC score	0.127948 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	P97501	Gene names	Fmo3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3).

FMO3_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.116121 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	P31513, Q14854, Q8N5N5	Gene names	FMO3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3) (FMO form 2) (FMO II).

DPYD_HUMAN
θ value	0.365318 (rank : 18)	NC score	0.072267 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q12882, Q16694, Q16761, Q96TH1	Gene names	DPYD
Domain Architecture
Description	Dihydropyrimidine dehydrogenase [NADP+] precursor (EC 1.3.1.2) (DPD) (DHPDHase) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase).

PCYOX_MOUSE
θ value	0.47712 (rank : 19)	NC score	0.072428 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CQF9, Q3UHV6, Q69ZW0, Q8BZX1	Gene names	Pcyox1, Kiaa0908
Domain Architecture	No domain graphic available
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5).

FMO6_HUMAN
θ value	0.62314 (rank : 20)	NC score	0.101988 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	O60774	Gene names	FMO6
Domain Architecture
Description	Putative dimethylaniline monooxygenase [N-oxide-forming] 6 (EC 1.14.13.8) (Flavin-containing monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6).

OXLA_MOUSE
θ value	0.62314 (rank : 21)	NC score	0.268956 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

PPOX_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.174476 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

PPOX_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.145703 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	P51175, P97344, Q99M34	Gene names	Ppox
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

FMO5_MOUSE
θ value	0.813845 (rank : 24)	NC score	0.087985 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P97872	Gene names	Fmo5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

FMO2_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.097374 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K2I3, Q9QZF7	Gene names	Fmo2
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2).

M2GD_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.032289 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI17	Gene names	DMGDH
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

LPIN3_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.014818 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PI4, Q3TQ75, Q8C7R9	Gene names	Lpin3
Domain Architecture
Description	Lipin-3.

PRD15_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.001259 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	805	Shared Neighborhood Hits	3
SwissProt Accessions	P57071, Q8N0X3, Q8NEX0, Q9NQV3	Gene names	PRDM15, C21orf83, ZNF298
Domain Architecture
Description	PR domain zinc finger protein 15 (PR domain-containing protein 15) (Zinc finger protein 298).

PTN22_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.006627 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

FMO2_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.089740 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	21	Shared Neighborhood Hits	19
SwissProt Accessions	Q99518, Q5EBX4, Q9BRX1	Gene names	FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1).

SIM2_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.008335 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

FMO4_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.078241 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHG0	Gene names	Fmo4
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

FMO4_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.086990 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	P31512	Gene names	FMO4, FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

TNK1_MOUSE
θ value	6.88961 (rank : 34)	NC score	-0.000539 (rank : 36)
Query Neighborhood Hits	35	Target Neighborhood Hits	806	Shared Neighborhood Hits	2
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

RUFY1_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.003603 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	765	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

FMO5_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.075201 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	P49326	Gene names	FMO5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

Hits sorted by NC score

SMOX_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

SMOX_MOUSE
NC score	0.998287 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	34	Shared Neighborhood Hits	29
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

PAOX_MOUSE
NC score	0.944908 (rank : 3)	θ value	4.95767e-99 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C0L6, Q8K254	Gene names	Paox, Pao
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

PAOX_HUMAN
NC score	0.943060 (rank : 4)	θ value	1.39714e-93 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q6QHF9, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0, Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, Q6QHG5, Q6QHG6, Q86WP9, Q8N555, Q8NCX3	Gene names	PAOX, PAO
Domain Architecture	No domain graphic available
Description	Peroxisomal N1-acetyl-spermine/spermidine oxidase (EC 1.5.3.11) (Polyamine oxidase).

AOF1_HUMAN
NC score	0.729835 (rank : 5)	θ value	1.02001e-27 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOF1_MOUSE
NC score	0.727882 (rank : 6)	θ value	5.06226e-27 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

LSD1_MOUSE
NC score	0.723499 (rank : 7)	θ value	1.85889e-29 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	224	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_HUMAN
NC score	0.691559 (rank : 8)	θ value	1.85889e-29 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	455	Shared Neighborhood Hits	23
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

AOFB_HUMAN
NC score	0.379903 (rank : 9)	θ value	9.29e-05 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	P27338, Q7Z6S2	Gene names	MAOB
Domain Architecture
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFB_MOUSE
NC score	0.332578 (rank : 10)	θ value	0.00869519 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BW75, Q8C0B2	Gene names	Maob
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B).

AOFA_MOUSE
NC score	0.330025 (rank : 11)	θ value	0.00020696 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	Q64133, Q8K0Z8	Gene names	Maoa
Domain Architecture	No domain graphic available
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

AOFA_HUMAN
NC score	0.308823 (rank : 12)	θ value	0.00390308 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	21
SwissProt Accessions	P21397, Q16426	Gene names	MAOA
Domain Architecture
Description	Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A).

OXLA_MOUSE
NC score	0.268956 (rank : 13)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

OXLA_HUMAN
NC score	0.257739 (rank : 14)	θ value	0.0330416 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

PPOX_HUMAN
NC score	0.174476 (rank : 15)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P50336	Gene names	PPOX
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

PPOX_MOUSE
NC score	0.145703 (rank : 16)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	P51175, P97344, Q99M34	Gene names	Ppox
Domain Architecture
Description	Protoporphyrinogen oxidase (EC 1.3.3.4) (PPO).

FMO3_MOUSE
NC score	0.127948 (rank : 17)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	P97501	Gene names	Fmo3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3).

FMO3_HUMAN
NC score	0.116121 (rank : 18)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	P31513, Q14854, Q8N5N5	Gene names	FMO3
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Dimethylaniline oxidase 3) (FMO form 2) (FMO II).

FMO1_HUMAN
NC score	0.110776 (rank : 19)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	21
SwissProt Accessions	Q01740, Q5QPT2, Q9UJC2	Gene names	FMO1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Fetal hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO1_MOUSE
NC score	0.107094 (rank : 20)	θ value	0.0431538 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	18	Shared Neighborhood Hits	17
SwissProt Accessions	P50285	Gene names	Fmo1, Fmo-1
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1).

FMO6_HUMAN
NC score	0.101988 (rank : 21)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	O60774	Gene names	FMO6
Domain Architecture
Description	Putative dimethylaniline monooxygenase [N-oxide-forming] 6 (EC 1.14.13.8) (Flavin-containing monooxygenase 6) (FMO 6) (Dimethylaniline oxidase 6).

FMO2_MOUSE
NC score	0.097374 (rank : 22)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K2I3, Q9QZF7	Gene names	Fmo2
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2).

FMO2_HUMAN
NC score	0.089740 (rank : 23)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	21	Shared Neighborhood Hits	19
SwissProt Accessions	Q99518, Q5EBX4, Q9BRX1	Gene names	FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1).

FMO5_MOUSE
NC score	0.087985 (rank : 24)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P97872	Gene names	Fmo5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

FMO4_HUMAN
NC score	0.086990 (rank : 25)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	P31512	Gene names	FMO4, FMO2
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

FMO4_MOUSE
NC score	0.078241 (rank : 26)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHG0	Gene names	Fmo4
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (Dimethylaniline oxidase 4).

FMO5_HUMAN
NC score	0.075201 (rank : 27)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	35	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	P49326	Gene names	FMO5
Domain Architecture
Description	Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC 1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5).

PCYOX_MOUSE
NC score	0.072428 (rank : 28)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CQF9, Q3UHV6, Q69ZW0, Q8BZX1	Gene names	Pcyox1, Kiaa0908
Domain Architecture	No domain graphic available
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5).

DPYD_HUMAN
NC score	0.072267 (rank : 29)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q12882, Q16694, Q16761, Q96TH1	Gene names	DPYD
Domain Architecture
Description	Dihydropyrimidine dehydrogenase [NADP+] precursor (EC 1.3.1.2) (DPD) (DHPDHase) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase).

M2GD_HUMAN
NC score	0.032289 (rank : 30)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI17	Gene names	DMGDH
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

LPIN3_MOUSE
NC score	0.014818 (rank : 31)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PI4, Q3TQ75, Q8C7R9	Gene names	Lpin3
Domain Architecture
Description	Lipin-3.

SIM2_HUMAN
NC score	0.008335 (rank : 32)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

PTN22_HUMAN
NC score	0.006627 (rank : 33)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

RUFY1_MOUSE
NC score	0.003603 (rank : 34)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	765	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

PRD15_HUMAN
NC score	0.001259 (rank : 35)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	805	Shared Neighborhood Hits	3
SwissProt Accessions	P57071, Q8N0X3, Q8NEX0, Q9NQV3	Gene names	PRDM15, C21orf83, ZNF298
Domain Architecture
Description	PR domain zinc finger protein 15 (PR domain-containing protein 15) (Zinc finger protein 298).

TNK1_MOUSE
NC score	-0.000539 (rank : 36)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	806	Shared Neighborhood Hits	2
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).