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Network neighborhood for query Sequence : DPYD_HUMAN

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DPYD_HUMAN
SwissProt Accessions	Q12882, Q16694, Q16761, Q96TH1	Gene names	DPYD
Domain Architecture
Description	Dihydropyrimidine dehydrogenase [NADP+] precursor (EC 1.3.1.2) (DPD) (DHPDHase) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DPYD_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q12882, Q16694, Q16761, Q96TH1	Gene names	DPYD
Domain Architecture
Description	Dihydropyrimidine dehydrogenase [NADP+] precursor (EC 1.3.1.2) (DPD) (DHPDHase) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase).

PYRD_MOUSE
θ value	2.36244e-08 (rank : 2)	NC score	0.375166 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	O35435	Gene names	Dhodh
Domain Architecture
Description	Dihydroorotate dehydrogenase, mitochondrial precursor (EC 1.3.3.1) (Dihydroorotate oxidase) (DHOdehase).

PYRD_HUMAN
θ value	6.87365e-08 (rank : 3)	NC score	0.367397 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q02127, Q6P176	Gene names	DHODH
Domain Architecture	No domain graphic available
Description	Dihydroorotate dehydrogenase, mitochondrial precursor (EC 1.3.3.1) (Dihydroorotate oxidase) (DHOdehase).

DUS1L_HUMAN
θ value	0.21417 (rank : 4)	NC score	0.109237 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P1R4, Q96AI3	Gene names	DUS1L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 1-like (EC 1.-.-.-).

MYOG_HUMAN
θ value	0.21417 (rank : 5)	NC score	0.106837 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYOG_MOUSE
θ value	0.21417 (rank : 6)	NC score	0.106299 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

FIGLA_MOUSE
θ value	0.279714 (rank : 7)	NC score	0.088590 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

SMOX_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.072267 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

SMOX_MOUSE
θ value	0.47712 (rank : 9)	NC score	0.070925 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

DUS1L_MOUSE
θ value	0.62314 (rank : 10)	NC score	0.102291 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C2P3, Q8VCN7, Q9D124	Gene names	Dus1l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 1-like (EC 1.-.-.-).

DUS4L_MOUSE
θ value	0.62314 (rank : 11)	NC score	0.101191 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q32M08, Q9D6P4	Gene names	Dus4l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 4-like (EC 1.-.-.-).

FIGLA_HUMAN
θ value	0.62314 (rank : 12)	NC score	0.080126 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

DUS4L_HUMAN
θ value	0.813845 (rank : 13)	NC score	0.098716 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O95620, Q2NKK1	Gene names	DUS4L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 4-like (EC 1.-.-.-) (PP35).

MYF5_MOUSE
θ value	0.813845 (rank : 14)	NC score	0.076939 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

ST18_MOUSE
θ value	0.813845 (rank : 15)	NC score	0.033761 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TY4, Q3UH00, Q3URH9, Q3UVB9, Q3UZN9, Q811B4, Q8K098	Gene names	St18, Kiaa0535
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18.

ABCE1_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.056485 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	P61221, O88793, Q13181, Q13864, Q6NR76, Q96AL0, Q96B10, Q99K66	Gene names	ABCE1, RLI
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) (2'-5' oligoadenylate-binding protein) (HuHP68).

ABCE1_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.056485 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	P61222, O88793, Q13181, Q13864, Q96AL0, Q96B10, Q99K66	Gene names	Abce1, Rli
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I).

MTO1_HUMAN
θ value	2.36792 (rank : 18)	NC score	0.040910 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2Z2, Q5SWL2, Q5SWL3, Q5SWL4, Q8NDN7, Q8WZ57, Q96FE6, Q9BS06	Gene names	MTO1
Domain Architecture
Description	Protein MTO1 homolog, mitochondrial precursor.

SIA1B_MOUSE
θ value	2.36792 (rank : 19)	NC score	0.028244 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

CSK21_MOUSE
θ value	4.03905 (rank : 20)	NC score	0.004330 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	770	Shared Neighborhood Hits	2
SwissProt Accessions	Q60737	Gene names	Csnk2a1, Ckiia
Domain Architecture
Description	Casein kinase II subunit alpha (EC 2.7.11.1) (CK II).

HAP1_MOUSE
θ value	4.03905 (rank : 21)	NC score	0.025529 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	388	Shared Neighborhood Hits	4
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

HOOK2_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.012924 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	714	Shared Neighborhood Hits	4
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

MCR_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.011341 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	162	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

P3C2A_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.018725 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

CJ033_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.040634 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N2H3, Q5TAA9, Q9BRQ1	Gene names	C10orf33
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 (EC 1.-.-.-).

CJ033_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.039889 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q3U4I7, Q8CAN2, Q9D630	Gene names
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 homolog (EC 1.-.-.-).

SYNE1_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.008392 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	1484	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ZN100_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.001955 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	734	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYN0	Gene names	ZNF100
Domain Architecture	No domain graphic available
Description	Zinc finger protein 100.

BMPER_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.012864 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CCD1A_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.022225 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1A6, Q2MJB5, Q8R3Z4	Gene names	Cc2d1a
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1).

P3C2A_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.016965 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

PACE1_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.020073 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZE3, Q5THA6, Q5THA8, Q8IZN9, Q96C56, Q9UBK6	Gene names	SCYL3, PACE1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

PLXD1_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.009804 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

ZN11B_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.001720 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	802	Shared Neighborhood Hits	4
SwissProt Accessions	Q06732, Q86XY8, Q8NDW3	Gene names	ZNF11B
Domain Architecture	No domain graphic available
Description	Zinc finger protein 11B.

CUTC_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.022041 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NTM9, Q9Y321	Gene names	CUTC
Domain Architecture	No domain graphic available
Description	Copper homeostasis protein cutC homolog.

MYF5_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.059374 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

ZN473_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.001744 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	824	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BI67, Q8BI98, Q8BIB7	Gene names	Znf473, Zfp100, Zfp473
Domain Architecture	No domain graphic available
Description	Zinc finger protein 473 homolog (Zinc finger protein 100) (Zfp-100).

Hits sorted by NC score

DPYD_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q12882, Q16694, Q16761, Q96TH1	Gene names	DPYD
Domain Architecture
Description	Dihydropyrimidine dehydrogenase [NADP+] precursor (EC 1.3.1.2) (DPD) (DHPDHase) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase).

PYRD_MOUSE
NC score	0.375166 (rank : 2)	θ value	2.36244e-08 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	O35435	Gene names	Dhodh
Domain Architecture
Description	Dihydroorotate dehydrogenase, mitochondrial precursor (EC 1.3.3.1) (Dihydroorotate oxidase) (DHOdehase).

PYRD_HUMAN
NC score	0.367397 (rank : 3)	θ value	6.87365e-08 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q02127, Q6P176	Gene names	DHODH
Domain Architecture	No domain graphic available
Description	Dihydroorotate dehydrogenase, mitochondrial precursor (EC 1.3.3.1) (Dihydroorotate oxidase) (DHOdehase).

DUS1L_HUMAN
NC score	0.109237 (rank : 4)	θ value	0.21417 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P1R4, Q96AI3	Gene names	DUS1L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 1-like (EC 1.-.-.-).

MYOG_HUMAN
NC score	0.106837 (rank : 5)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYOG_MOUSE
NC score	0.106299 (rank : 6)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

DUS1L_MOUSE
NC score	0.102291 (rank : 7)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C2P3, Q8VCN7, Q9D124	Gene names	Dus1l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 1-like (EC 1.-.-.-).

DUS4L_MOUSE
NC score	0.101191 (rank : 8)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q32M08, Q9D6P4	Gene names	Dus4l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 4-like (EC 1.-.-.-).

DUS4L_HUMAN
NC score	0.098716 (rank : 9)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O95620, Q2NKK1	Gene names	DUS4L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 4-like (EC 1.-.-.-) (PP35).

FIGLA_MOUSE
NC score	0.088590 (rank : 10)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

FIGLA_HUMAN
NC score	0.080126 (rank : 11)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

MYF5_MOUSE
NC score	0.076939 (rank : 12)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

SMOX_HUMAN
NC score	0.072267 (rank : 13)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWM0, Q5TE26, Q5TE27, Q6UY28, Q8IX00, Q96LC3, Q96LC4, Q96QT3, Q9BW38, Q9H6H1, Q9NP51, Q9NPY1, Q9NPY2	Gene names	SMOX, C20orf16, SMO
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

SMOX_MOUSE
NC score	0.070925 (rank : 14)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q99K82, Q70LA3, Q70LA4, Q70LA5, Q70LA7, Q70LA8, Q70LA9, Q70LB0, Q8CJ56, Q8CJ57	Gene names	Smox, Smo
Domain Architecture	No domain graphic available
Description	Spermine oxidase (EC 1.5.3.-) (Polyamine oxidase 1) (PAO-1) (PAOh1).

MYF5_HUMAN
NC score	0.059374 (rank : 15)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

ABCE1_HUMAN
NC score	0.056485 (rank : 16)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	P61221, O88793, Q13181, Q13864, Q6NR76, Q96AL0, Q96B10, Q99K66	Gene names	ABCE1, RLI
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) (2'-5' oligoadenylate-binding protein) (HuHP68).

ABCE1_MOUSE
NC score	0.056485 (rank : 17)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	P61222, O88793, Q13181, Q13864, Q96AL0, Q96B10, Q99K66	Gene names	Abce1, Rli
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I).

MTO1_HUMAN
NC score	0.040910 (rank : 18)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2Z2, Q5SWL2, Q5SWL3, Q5SWL4, Q8NDN7, Q8WZ57, Q96FE6, Q9BS06	Gene names	MTO1
Domain Architecture
Description	Protein MTO1 homolog, mitochondrial precursor.

CJ033_HUMAN
NC score	0.040634 (rank : 19)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N2H3, Q5TAA9, Q9BRQ1	Gene names	C10orf33
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 (EC 1.-.-.-).

CJ033_MOUSE
NC score	0.039889 (rank : 20)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q3U4I7, Q8CAN2, Q9D630	Gene names
Domain Architecture	No domain graphic available
Description	Probable oxidoreductase C10orf33 homolog (EC 1.-.-.-).

ST18_MOUSE
NC score	0.033761 (rank : 21)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TY4, Q3UH00, Q3URH9, Q3UVB9, Q3UZN9, Q811B4, Q8K098	Gene names	St18, Kiaa0535
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18.

SIA1B_MOUSE
NC score	0.028244 (rank : 22)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

HAP1_MOUSE
NC score	0.025529 (rank : 23)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	388	Shared Neighborhood Hits	4
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

CCD1A_MOUSE
NC score	0.022225 (rank : 24)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1A6, Q2MJB5, Q8R3Z4	Gene names	Cc2d1a
Domain Architecture	No domain graphic available
Description	Coiled-coil and C2 domain-containing protein 1A (Five repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1).

CUTC_HUMAN
NC score	0.022041 (rank : 25)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NTM9, Q9Y321	Gene names	CUTC
Domain Architecture	No domain graphic available
Description	Copper homeostasis protein cutC homolog.

PACE1_HUMAN
NC score	0.020073 (rank : 26)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZE3, Q5THA6, Q5THA8, Q8IZN9, Q96C56, Q9UBK6	Gene names	SCYL3, PACE1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

P3C2A_HUMAN
NC score	0.018725 (rank : 27)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
NC score	0.016965 (rank : 28)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

HOOK2_HUMAN
NC score	0.012924 (rank : 29)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	714	Shared Neighborhood Hits	4
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

BMPER_HUMAN
NC score	0.012864 (rank : 30)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

MCR_MOUSE
NC score	0.011341 (rank : 31)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	162	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PLXD1_HUMAN
NC score	0.009804 (rank : 32)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

SYNE1_HUMAN
NC score	0.008392 (rank : 33)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	1484	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

CSK21_MOUSE
NC score	0.004330 (rank : 34)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	770	Shared Neighborhood Hits	2
SwissProt Accessions	Q60737	Gene names	Csnk2a1, Ckiia
Domain Architecture
Description	Casein kinase II subunit alpha (EC 2.7.11.1) (CK II).

ZN100_HUMAN
NC score	0.001955 (rank : 35)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	734	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYN0	Gene names	ZNF100
Domain Architecture	No domain graphic available
Description	Zinc finger protein 100.

ZN473_MOUSE
NC score	0.001744 (rank : 36)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	824	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BI67, Q8BI98, Q8BIB7	Gene names	Znf473, Zfp100, Zfp473
Domain Architecture	No domain graphic available
Description	Zinc finger protein 473 homolog (Zinc finger protein 100) (Zfp-100).

ZN11B_HUMAN
NC score	0.001720 (rank : 37)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	802	Shared Neighborhood Hits	4
SwissProt Accessions	Q06732, Q86XY8, Q8NDW3	Gene names	ZNF11B
Domain Architecture	No domain graphic available
Description	Zinc finger protein 11B.