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Network neighborhood for query Sequence : PLXD1_HUMAN

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PLXD1_HUMAN
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PLXA1_HUMAN
θ value	0 (rank : 1)	NC score	0.974030 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	108	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

PLXA1_MOUSE
θ value	0 (rank : 2)	NC score	0.973570 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	107	Shared Neighborhood Hits	61
SwissProt Accessions	P70206, Q5DTR0	Gene names	Plxna1, KIAA4053
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Plexin-1) (Plex 1).

PLXA2_HUMAN
θ value	0 (rank : 3)	NC score	0.974011 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	100	Shared Neighborhood Hits	61
SwissProt Accessions	O75051, Q6UX61, Q96GN9, Q9BRL1, Q9UIW1	Gene names	PLXNA2, KIAA0463, OCT
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Semaphorin receptor OCT).

PLXA2_MOUSE
θ value	0 (rank : 4)	NC score	0.974014 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	97	Shared Neighborhood Hits	61
SwissProt Accessions	P70207, Q6NVE6, Q6PHN4, Q80TZ7, Q8R1I4	Gene names	Plxna2, Kiaa0463
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Plexin-2) (Plex 2).

PLXA3_HUMAN
θ value	0 (rank : 5)	NC score	0.974430 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	P51805	Gene names	PLXNA3, PLXN4, SEX
Domain Architecture
Description	Plexin-A3 precursor (Plexin-4) (Semaphorin receptor SEX).

PLXA4_HUMAN
θ value	0 (rank : 6)	NC score	0.972516 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	106	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA4_MOUSE
θ value	0 (rank : 7)	NC score	0.972445 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	109	Shared Neighborhood Hits	63
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXB1_HUMAN
θ value	0 (rank : 8)	NC score	0.948625 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	360	Shared Neighborhood Hits	60
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PLXB1_MOUSE
θ value	0 (rank : 9)	NC score	0.959422 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	259	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PLXB3_HUMAN
θ value	0 (rank : 10)	NC score	0.978318 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	106	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

PLXB3_MOUSE
θ value	0 (rank : 11)	NC score	0.977744 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	94	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

PLXD1_HUMAN
θ value	0 (rank : 12)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

PLXB2_HUMAN
θ value	9.49765e-159 (rank : 13)	NC score	0.966745 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	94	Shared Neighborhood Hits	61
SwissProt Accessions	O15031, Q7KZU3, Q9BSU7	Gene names	PLXNB2, KIAA0315
Domain Architecture	No domain graphic available
Description	Plexin-B2 precursor (MM1).

PLXC1_HUMAN
θ value	8.0589e-150 (rank : 14)	NC score	0.943883 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	94	Shared Neighborhood Hits	58
SwissProt Accessions	O60486, Q59H25	Gene names	PLXNC1, VESPR
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PLXC1_MOUSE
θ value	1.79534e-149 (rank : 15)	NC score	0.945648 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	84	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QZC2, Q8CGW1	Gene names	Plxnc1, Vespr
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

MET_MOUSE
θ value	5.42112e-21 (rank : 16)	NC score	0.202263 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	844	Shared Neighborhood Hits	29
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

RON_HUMAN
θ value	1.2077e-20 (rank : 17)	NC score	0.180713 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	842	Shared Neighborhood Hits	23
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

MET_HUMAN
θ value	7.82807e-20 (rank : 18)	NC score	0.202638 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	831	Shared Neighborhood Hits	23
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

RON_MOUSE
θ value	8.65492e-19 (rank : 19)	NC score	0.178070 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	836	Shared Neighborhood Hits	22
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

SEM4B_MOUSE
θ value	2.52405e-10 (rank : 20)	NC score	0.377976 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	67	Shared Neighborhood Hits	51
SwissProt Accessions	Q62179, Q4PKI6, Q69ZB7	Gene names	Sema4b, Kiaa1745, Semac, SemC
Domain Architecture	No domain graphic available
Description	Semaphorin-4B precursor (Semaphorin C) (Sema C).

SEM5B_HUMAN
θ value	1.80886e-08 (rank : 21)	NC score	0.300670 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	178	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SEM4B_HUMAN
θ value	4.0297e-08 (rank : 22)	NC score	0.365284 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	67	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NPR2, Q6UXE3, Q8WVP9, Q96FK5, Q9C0B8, Q9H691, Q9NPM8, Q9NPN0	Gene names	SEMA4B, KIAA1745
Domain Architecture
Description	Semaphorin-4B precursor.

SEM5B_MOUSE
θ value	1.99992e-07 (rank : 23)	NC score	0.298640 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	190	Shared Neighborhood Hits	52
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5A_MOUSE
θ value	1.29631e-06 (rank : 24)	NC score	0.294764 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

PKHD1_HUMAN
θ value	2.21117e-06 (rank : 25)	NC score	0.215182 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TCZ9	Gene names	PKHD1, FCYT, TIGM1
Domain Architecture
Description	Polycystic kidney and hepatic disease 1 precursor (Fibrocystin) (Polyductin) (Tigmin).

SEM5A_HUMAN
θ value	2.88788e-06 (rank : 26)	NC score	0.284410 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	177	Shared Neighborhood Hits	51
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM4C_HUMAN
θ value	6.43352e-06 (rank : 27)	NC score	0.342346 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	84	Shared Neighborhood Hits	52
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

SEM4C_MOUSE
θ value	8.40245e-06 (rank : 28)	NC score	0.310758 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	77	Shared Neighborhood Hits	52
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

SEM4D_HUMAN
θ value	1.09739e-05 (rank : 29)	NC score	0.280331 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	139	Shared Neighborhood Hits	55
SwissProt Accessions	Q92854, Q7Z5S4	Gene names	SEMA4D, CD100
Domain Architecture
Description	Semaphorin-4D precursor (Leukocyte activation antigen CD100) (BB18) (A8) (GR3).

SEM4A_MOUSE
θ value	1.87187e-05 (rank : 30)	NC score	0.360666 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	65	Shared Neighborhood Hits	51
SwissProt Accessions	Q62178	Gene names	Sema4a, Semab, SemB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM3C_MOUSE
θ value	9.29e-05 (rank : 31)	NC score	0.271242 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3C_HUMAN
θ value	0.000158464 (rank : 32)	NC score	0.269302 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3E_HUMAN
θ value	0.00020696 (rank : 33)	NC score	0.251411 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

SEM4D_MOUSE
θ value	0.00020696 (rank : 34)	NC score	0.291901 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	143	Shared Neighborhood Hits	53
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SEM4A_HUMAN
θ value	0.000602161 (rank : 35)	NC score	0.364564 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	61	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3S1, Q8WUA9	Gene names	SEMA4A, SEMB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM6D_HUMAN
θ value	0.000602161 (rank : 36)	NC score	0.307362 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	169	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM4F_MOUSE
θ value	0.00102713 (rank : 37)	NC score	0.288407 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	59	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z123, Q9R1Y1	Gene names	Sema4f, Semaw
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W).

SEM4G_MOUSE
θ value	0.00134147 (rank : 38)	NC score	0.328462 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	99	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

SEM6D_MOUSE
θ value	0.00134147 (rank : 39)	NC score	0.308316 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	161	Shared Neighborhood Hits	51
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6A_HUMAN
θ value	0.00298849 (rank : 40)	NC score	0.291247 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	96	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

SEM4G_HUMAN
θ value	0.00665767 (rank : 41)	NC score	0.326668 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	88	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NTN9, Q9HCF3	Gene names	SEMA4G, KIAA1619
Domain Architecture
Description	Semaphorin-4G precursor.

SEM3E_MOUSE
θ value	0.0113563 (rank : 42)	NC score	0.246470 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	76	Shared Neighborhood Hits	51
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

SEM3F_MOUSE
θ value	0.0113563 (rank : 43)	NC score	0.281933 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

SEM6B_HUMAN
θ value	0.0193708 (rank : 44)	NC score	0.292465 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	187	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SEM3F_HUMAN
θ value	0.0252991 (rank : 45)	NC score	0.281686 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	100	Shared Neighborhood Hits	51
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

SEM6A_MOUSE
θ value	0.0252991 (rank : 46)	NC score	0.287732 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	96	Shared Neighborhood Hits	51
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

SEM7A_MOUSE
θ value	0.0330416 (rank : 47)	NC score	0.307172 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	64	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QUR8, O88371	Gene names	Sema7a, Cd108, Semal, Semk1
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (CD108 antigen) (CDw108).

SEM3D_HUMAN
θ value	0.0431538 (rank : 48)	NC score	0.244336 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	104	Shared Neighborhood Hits	49
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

SEM6B_MOUSE
θ value	0.0431538 (rank : 49)	NC score	0.275349 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	200	Shared Neighborhood Hits	51
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SEM4F_HUMAN
θ value	0.0563607 (rank : 50)	NC score	0.286263 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	57	Shared Neighborhood Hits	53
SwissProt Accessions	O95754, Q9NS35	Gene names	SEMA4F, SEMAM, SEMAW
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W) (Semaphorin M) (Sema M).

SEM3D_MOUSE
θ value	0.0736092 (rank : 51)	NC score	0.235954 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	97	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BH34	Gene names	Sema3d
Domain Architecture	No domain graphic available
Description	Semaphorin-3D precursor.

AKAP4_MOUSE
θ value	0.365318 (rank : 52)	NC score	0.029606 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q60662, Q60630, Q8R2G7	Gene names	Akap4, Akap82, Fsc1
Domain Architecture
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (mAKAP82) (Major sperm fibrous sheath protein) (FSC1) (p82).

SEM3B_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.267611 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	76	Shared Neighborhood Hits	51
SwissProt Accessions	Q13214, Q8TB71, Q8TDV7, Q93018, Q96GX0	Gene names	SEMA3B, SEMA5
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin V) (Sema V) (Sema A(V)).

ATRN_MOUSE
θ value	0.813845 (rank : 54)	NC score	0.060675 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	519	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

SEM3A_MOUSE
θ value	0.813845 (rank : 55)	NC score	0.246477 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	92	Shared Neighborhood Hits	50
SwissProt Accessions	O08665, Q5BL08, Q62180, Q62215	Gene names	Sema3a, Semad, SemD
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III) (Semaphorin D) (Sema D).

ATRN_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.068652 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	525	Shared Neighborhood Hits	20
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

MEGF8_MOUSE
θ value	1.06291 (rank : 57)	NC score	0.049128 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	520	Shared Neighborhood Hits	26
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SEM3B_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.271582 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	Q62177	Gene names	Sema3b, Sema, Semaa
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin A) (Sema A).

WEE1_MOUSE
θ value	1.06291 (rank : 59)	NC score	0.003713 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	794	Shared Neighborhood Hits	5
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

BST1_MOUSE
θ value	1.38821 (rank : 60)	NC score	0.016508 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q64277, Q8BRY3	Gene names	Bst1, Bp-3, Bp3, Ly65
Domain Architecture
Description	ADP-ribosyl cyclase 2 precursor (EC 3.2.2.5) (Cyclic ADP-ribose hydrolase 2) (cADPr hydrolase 2) (Bone marrow stromal antigen 1) (BST- 1) (BP-3 alloantigen) (Antigen BP3) (CD157 antigen).

LYAM1_MOUSE
θ value	1.38821 (rank : 61)	NC score	0.006712 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MEGF8_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.055079 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	528	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SEM3A_HUMAN
θ value	1.38821 (rank : 63)	NC score	0.242265 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	78	Shared Neighborhood Hits	50
SwissProt Accessions	Q14563	Gene names	SEMA3A
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III).

TISD_HUMAN
θ value	1.38821 (rank : 64)	NC score	0.014202 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	P47974, Q9BSJ3	Gene names	ZFP36L2, BRF2, ERF2, TIS11D
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein) (EGF-response factor 2) (ERF-2).

ANGL7_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.006108 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	O43827, Q4ZGK4	Gene names	ANGPTL7, CDT6
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7) (Angiopoietin-like factor) (Cornea-derived transcript 6 protein).

CXX1_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.029755 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	O15255	Gene names	CXX1
Domain Architecture	No domain graphic available
Description	CAAX box protein 1 (Cerebral protein 5).

MLX_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.018846 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.018641 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

RASA3_HUMAN
θ value	1.81305 (rank : 69)	NC score	0.065106 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

AIM2_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.017852 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	O14862	Gene names	AIM2
Domain Architecture
Description	Interferon-inducible protein AIM2 (Absent in melanoma 2).

CKAP5_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.016010 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

GBP1_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.005143 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	339	Shared Neighborhood Hits	3
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

DTBP1_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.009333 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

SEM7A_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.292852 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	67	Shared Neighborhood Hits	51
SwissProt Accessions	O75326	Gene names	SEMA7A, CD108, SEMAL
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (John-Milton-Hargen human blood group Ag) (JMH blood group antigen) (CD108 antigen) (CDw108).

CAD23_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.000101 (rank : 94)
Query Neighborhood Hits	89	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

KCNE3_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.013477 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTW2	Gene names	Kcne3
Domain Architecture
Description	Potassium voltage-gated channel subfamily E member 3 (Minimum potassium ion channel-related peptide 2) (Potassium channel subunit beta MiRP2) (MinK-related peptide 2).

AIM1_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.008754 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	247	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

ANGL7_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.004257 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1Q3	Gene names	Angptl7
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7).

DAP1_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.011798 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q91XC8	Gene names	Dap
Domain Architecture	No domain graphic available
Description	Death-associated protein 1 (DAP-1).

DPYD_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.009804 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q12882, Q16694, Q16761, Q96TH1	Gene names	DPYD
Domain Architecture
Description	Dihydropyrimidine dehydrogenase [NADP+] precursor (EC 1.3.1.2) (DPD) (DHPDHase) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase).

MAP1B_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.003139 (rank : 92)
Query Neighborhood Hits	89	Target Neighborhood Hits	903	Shared Neighborhood Hits	3
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAP1B_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.002603 (rank : 93)
Query Neighborhood Hits	89	Target Neighborhood Hits	977	Shared Neighborhood Hits	4
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

EXOC2_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.086791 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D4H1	Gene names	Exoc2, Sec5, Sec5l1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

HEM1_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.003648 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P13196	Gene names	ALAS1, ALASH
Domain Architecture
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

HS90B_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.003262 (rank : 91)
Query Neighborhood Hits	89	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

LMX1A_HUMAN
θ value	8.99809 (rank : 86)	NC score	-0.000838 (rank : 95)
Query Neighborhood Hits	89	Target Neighborhood Hits	406	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TE12, Q8TE11	Gene names	LMX1A
Domain Architecture
Description	LIM homeobox transcription factor 1 alpha (LIM/homeobox protein LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1).

ROM1_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.005657 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q03395	Gene names	ROM1, TSPAN23
Domain Architecture
Description	Rod outer segment membrane protein 1 (ROSP1) (Tetraspanin-23) (Tspan- 23).

SHC1_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.003597 (rank : 90)
Query Neighborhood Hits	89	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

SHC1_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.003731 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

EXOC2_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.091020 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

PXDC1_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.080605 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IUK5, Q5QCZ7, Q5QCZ8, Q5QCZ9, Q9HCT9	Gene names	PLXDC1, TEM3, TEM7
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 1 precursor (Tumor endothelial marker 7) (Tumor endothelial marker 3).

PXDC1_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.083792 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	14
SwissProt Accessions	Q91ZV7, Q8BM20, Q9CWV5	Gene names	Plxdc1, Tem7
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 1 precursor (Tumor endothelial marker 7).

PXDC2_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.052608 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UX71, Q96E59, Q96PD9, Q96SU9	Gene names	PLXDC2, TEM7R
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 2 precursor (Tumor endothelial marker 7-related protein).

SEM6C_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.273397 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM6C_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.246550 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	352	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

Hits sorted by NC score

PLXD1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

PLXB3_HUMAN
NC score	0.978318 (rank : 2)	θ value	0 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	106	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

PLXB3_MOUSE
NC score	0.977744 (rank : 3)	θ value	0 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	94	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

PLXA3_HUMAN
NC score	0.974430 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	P51805	Gene names	PLXNA3, PLXN4, SEX
Domain Architecture
Description	Plexin-A3 precursor (Plexin-4) (Semaphorin receptor SEX).

PLXA1_HUMAN
NC score	0.974030 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	108	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

PLXA2_MOUSE
NC score	0.974014 (rank : 6)	θ value	0 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	97	Shared Neighborhood Hits	61
SwissProt Accessions	P70207, Q6NVE6, Q6PHN4, Q80TZ7, Q8R1I4	Gene names	Plxna2, Kiaa0463
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Plexin-2) (Plex 2).

PLXA2_HUMAN
NC score	0.974011 (rank : 7)	θ value	0 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	100	Shared Neighborhood Hits	61
SwissProt Accessions	O75051, Q6UX61, Q96GN9, Q9BRL1, Q9UIW1	Gene names	PLXNA2, KIAA0463, OCT
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Semaphorin receptor OCT).

PLXA1_MOUSE
NC score	0.973570 (rank : 8)	θ value	0 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	107	Shared Neighborhood Hits	61
SwissProt Accessions	P70206, Q5DTR0	Gene names	Plxna1, KIAA4053
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Plexin-1) (Plex 1).

PLXA4_HUMAN
NC score	0.972516 (rank : 9)	θ value	0 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	106	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA4_MOUSE
NC score	0.972445 (rank : 10)	θ value	0 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	109	Shared Neighborhood Hits	63
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXB2_HUMAN
NC score	0.966745 (rank : 11)	θ value	9.49765e-159 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	94	Shared Neighborhood Hits	61
SwissProt Accessions	O15031, Q7KZU3, Q9BSU7	Gene names	PLXNB2, KIAA0315
Domain Architecture	No domain graphic available
Description	Plexin-B2 precursor (MM1).

PLXB1_MOUSE
NC score	0.959422 (rank : 12)	θ value	0 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	259	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PLXB1_HUMAN
NC score	0.948625 (rank : 13)	θ value	0 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	360	Shared Neighborhood Hits	60
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PLXC1_MOUSE
NC score	0.945648 (rank : 14)	θ value	1.79534e-149 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	84	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QZC2, Q8CGW1	Gene names	Plxnc1, Vespr
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PLXC1_HUMAN
NC score	0.943883 (rank : 15)	θ value	8.0589e-150 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	94	Shared Neighborhood Hits	58
SwissProt Accessions	O60486, Q59H25	Gene names	PLXNC1, VESPR
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

SEM4B_MOUSE
NC score	0.377976 (rank : 16)	θ value	2.52405e-10 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	67	Shared Neighborhood Hits	51
SwissProt Accessions	Q62179, Q4PKI6, Q69ZB7	Gene names	Sema4b, Kiaa1745, Semac, SemC
Domain Architecture	No domain graphic available
Description	Semaphorin-4B precursor (Semaphorin C) (Sema C).

SEM4B_HUMAN
NC score	0.365284 (rank : 17)	θ value	4.0297e-08 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	67	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NPR2, Q6UXE3, Q8WVP9, Q96FK5, Q9C0B8, Q9H691, Q9NPM8, Q9NPN0	Gene names	SEMA4B, KIAA1745
Domain Architecture
Description	Semaphorin-4B precursor.

SEM4A_HUMAN
NC score	0.364564 (rank : 18)	θ value	0.000602161 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	61	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3S1, Q8WUA9	Gene names	SEMA4A, SEMB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4A_MOUSE
NC score	0.360666 (rank : 19)	θ value	1.87187e-05 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	65	Shared Neighborhood Hits	51
SwissProt Accessions	Q62178	Gene names	Sema4a, Semab, SemB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4C_HUMAN
NC score	0.342346 (rank : 20)	θ value	6.43352e-06 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	84	Shared Neighborhood Hits	52
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

SEM4G_MOUSE
NC score	0.328462 (rank : 21)	θ value	0.00134147 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	99	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

SEM4G_HUMAN
NC score	0.326668 (rank : 22)	θ value	0.00665767 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	88	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NTN9, Q9HCF3	Gene names	SEMA4G, KIAA1619
Domain Architecture
Description	Semaphorin-4G precursor.

SEM4C_MOUSE
NC score	0.310758 (rank : 23)	θ value	8.40245e-06 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	77	Shared Neighborhood Hits	52
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

SEM6D_MOUSE
NC score	0.308316 (rank : 24)	θ value	0.00134147 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	161	Shared Neighborhood Hits	51
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6D_HUMAN
NC score	0.307362 (rank : 25)	θ value	0.000602161 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	169	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM7A_MOUSE
NC score	0.307172 (rank : 26)	θ value	0.0330416 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	64	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QUR8, O88371	Gene names	Sema7a, Cd108, Semal, Semk1
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (CD108 antigen) (CDw108).

SEM5B_HUMAN
NC score	0.300670 (rank : 27)	θ value	1.80886e-08 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	178	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SEM5B_MOUSE
NC score	0.298640 (rank : 28)	θ value	1.99992e-07 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	190	Shared Neighborhood Hits	52
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5A_MOUSE
NC score	0.294764 (rank : 29)	θ value	1.29631e-06 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM7A_HUMAN
NC score	0.292852 (rank : 30)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	67	Shared Neighborhood Hits	51
SwissProt Accessions	O75326	Gene names	SEMA7A, CD108, SEMAL
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (John-Milton-Hargen human blood group Ag) (JMH blood group antigen) (CD108 antigen) (CDw108).

SEM6B_HUMAN
NC score	0.292465 (rank : 31)	θ value	0.0193708 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	187	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SEM4D_MOUSE
NC score	0.291901 (rank : 32)	θ value	0.00020696 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	143	Shared Neighborhood Hits	53
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SEM6A_HUMAN
NC score	0.291247 (rank : 33)	θ value	0.00298849 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	96	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

SEM4F_MOUSE
NC score	0.288407 (rank : 34)	θ value	0.00102713 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	59	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z123, Q9R1Y1	Gene names	Sema4f, Semaw
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W).

SEM6A_MOUSE
NC score	0.287732 (rank : 35)	θ value	0.0252991 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	96	Shared Neighborhood Hits	51
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

SEM4F_HUMAN
NC score	0.286263 (rank : 36)	θ value	0.0563607 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	57	Shared Neighborhood Hits	53
SwissProt Accessions	O95754, Q9NS35	Gene names	SEMA4F, SEMAM, SEMAW
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W) (Semaphorin M) (Sema M).

SEM5A_HUMAN
NC score	0.284410 (rank : 37)	θ value	2.88788e-06 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	177	Shared Neighborhood Hits	51
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM3F_MOUSE
NC score	0.281933 (rank : 38)	θ value	0.0113563 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

SEM3F_HUMAN
NC score	0.281686 (rank : 39)	θ value	0.0252991 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	100	Shared Neighborhood Hits	51
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

SEM4D_HUMAN
NC score	0.280331 (rank : 40)	θ value	1.09739e-05 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	139	Shared Neighborhood Hits	55
SwissProt Accessions	Q92854, Q7Z5S4	Gene names	SEMA4D, CD100
Domain Architecture
Description	Semaphorin-4D precursor (Leukocyte activation antigen CD100) (BB18) (A8) (GR3).

SEM6B_MOUSE
NC score	0.275349 (rank : 41)	θ value	0.0431538 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	200	Shared Neighborhood Hits	51
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SEM6C_HUMAN
NC score	0.273397 (rank : 42)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	89	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM3B_MOUSE
NC score	0.271582 (rank : 43)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	Q62177	Gene names	Sema3b, Sema, Semaa
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin A) (Sema A).

SEM3C_MOUSE
NC score	0.271242 (rank : 44)	θ value	9.29e-05 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3C_HUMAN
NC score	0.269302 (rank : 45)	θ value	0.000158464 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3B_HUMAN
NC score	0.267611 (rank : 46)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	76	Shared Neighborhood Hits	51
SwissProt Accessions	Q13214, Q8TB71, Q8TDV7, Q93018, Q96GX0	Gene names	SEMA3B, SEMA5
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin V) (Sema V) (Sema A(V)).

SEM3E_HUMAN
NC score	0.251411 (rank : 47)	θ value	0.00020696 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

SEM6C_MOUSE
NC score	0.246550 (rank : 48)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	89	Target Neighborhood Hits	352	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM3A_MOUSE
NC score	0.246477 (rank : 49)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	92	Shared Neighborhood Hits	50
SwissProt Accessions	O08665, Q5BL08, Q62180, Q62215	Gene names	Sema3a, Semad, SemD
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III) (Semaphorin D) (Sema D).

SEM3E_MOUSE
NC score	0.246470 (rank : 50)	θ value	0.0113563 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	76	Shared Neighborhood Hits	51
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

SEM3D_HUMAN
NC score	0.244336 (rank : 51)	θ value	0.0431538 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	104	Shared Neighborhood Hits	49
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

SEM3A_HUMAN
NC score	0.242265 (rank : 52)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	78	Shared Neighborhood Hits	50
SwissProt Accessions	Q14563	Gene names	SEMA3A
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III).

SEM3D_MOUSE
NC score	0.235954 (rank : 53)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	97	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BH34	Gene names	Sema3d
Domain Architecture	No domain graphic available
Description	Semaphorin-3D precursor.

PKHD1_HUMAN
NC score	0.215182 (rank : 54)	θ value	2.21117e-06 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TCZ9	Gene names	PKHD1, FCYT, TIGM1
Domain Architecture
Description	Polycystic kidney and hepatic disease 1 precursor (Fibrocystin) (Polyductin) (Tigmin).

MET_HUMAN
NC score	0.202638 (rank : 55)	θ value	7.82807e-20 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	831	Shared Neighborhood Hits	23
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
NC score	0.202263 (rank : 56)	θ value	5.42112e-21 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	844	Shared Neighborhood Hits	29
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

RON_HUMAN
NC score	0.180713 (rank : 57)	θ value	1.2077e-20 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	842	Shared Neighborhood Hits	23
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
NC score	0.178070 (rank : 58)	θ value	8.65492e-19 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	836	Shared Neighborhood Hits	22
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

EXOC2_HUMAN
NC score	0.091020 (rank : 59)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

EXOC2_MOUSE
NC score	0.086791 (rank : 60)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D4H1	Gene names	Exoc2, Sec5, Sec5l1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

PXDC1_MOUSE
NC score	0.083792 (rank : 61)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	14
SwissProt Accessions	Q91ZV7, Q8BM20, Q9CWV5	Gene names	Plxdc1, Tem7
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 1 precursor (Tumor endothelial marker 7).

PXDC1_HUMAN
NC score	0.080605 (rank : 62)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	89	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IUK5, Q5QCZ7, Q5QCZ8, Q5QCZ9, Q9HCT9	Gene names	PLXDC1, TEM3, TEM7
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 1 precursor (Tumor endothelial marker 7) (Tumor endothelial marker 3).

ATRN_HUMAN
NC score	0.068652 (rank : 63)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	525	Shared Neighborhood Hits	20
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

RASA3_HUMAN
NC score	0.065106 (rank : 64)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

ATRN_MOUSE
NC score	0.060675 (rank : 65)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	519	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

MEGF8_HUMAN
NC score	0.055079 (rank : 66)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	528	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

PXDC2_HUMAN
NC score	0.052608 (rank : 67)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	89	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UX71, Q96E59, Q96PD9, Q96SU9	Gene names	PLXDC2, TEM7R
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 2 precursor (Tumor endothelial marker 7-related protein).

MEGF8_MOUSE
NC score	0.049128 (rank : 68)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	520	Shared Neighborhood Hits	26
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

CXX1_HUMAN
NC score	0.029755 (rank : 69)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	O15255	Gene names	CXX1
Domain Architecture	No domain graphic available
Description	CAAX box protein 1 (Cerebral protein 5).

AKAP4_MOUSE
NC score	0.029606 (rank : 70)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q60662, Q60630, Q8R2G7	Gene names	Akap4, Akap82, Fsc1
Domain Architecture
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (mAKAP82) (Major sperm fibrous sheath protein) (FSC1) (p82).

MLX_HUMAN
NC score	0.018846 (rank : 71)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
NC score	0.018641 (rank : 72)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

AIM2_HUMAN
NC score	0.017852 (rank : 73)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	O14862	Gene names	AIM2
Domain Architecture
Description	Interferon-inducible protein AIM2 (Absent in melanoma 2).

BST1_MOUSE
NC score	0.016508 (rank : 74)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q64277, Q8BRY3	Gene names	Bst1, Bp-3, Bp3, Ly65
Domain Architecture
Description	ADP-ribosyl cyclase 2 precursor (EC 3.2.2.5) (Cyclic ADP-ribose hydrolase 2) (cADPr hydrolase 2) (Bone marrow stromal antigen 1) (BST- 1) (BP-3 alloantigen) (Antigen BP3) (CD157 antigen).

CKAP5_HUMAN
NC score	0.016010 (rank : 75)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

TISD_HUMAN
NC score	0.014202 (rank : 76)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	P47974, Q9BSJ3	Gene names	ZFP36L2, BRF2, ERF2, TIS11D
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein) (EGF-response factor 2) (ERF-2).

KCNE3_MOUSE
NC score	0.013477 (rank : 77)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTW2	Gene names	Kcne3
Domain Architecture
Description	Potassium voltage-gated channel subfamily E member 3 (Minimum potassium ion channel-related peptide 2) (Potassium channel subunit beta MiRP2) (MinK-related peptide 2).

DAP1_MOUSE
NC score	0.011798 (rank : 78)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q91XC8	Gene names	Dap
Domain Architecture	No domain graphic available
Description	Death-associated protein 1 (DAP-1).

DPYD_HUMAN
NC score	0.009804 (rank : 79)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q12882, Q16694, Q16761, Q96TH1	Gene names	DPYD
Domain Architecture
Description	Dihydropyrimidine dehydrogenase [NADP+] precursor (EC 1.3.1.2) (DPD) (DHPDHase) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase).

DTBP1_MOUSE
NC score	0.009333 (rank : 80)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

AIM1_HUMAN
NC score	0.008754 (rank : 81)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	247	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

LYAM1_MOUSE
NC score	0.006712 (rank : 82)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

ANGL7_HUMAN
NC score	0.006108 (rank : 83)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	O43827, Q4ZGK4	Gene names	ANGPTL7, CDT6
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7) (Angiopoietin-like factor) (Cornea-derived transcript 6 protein).

ROM1_HUMAN
NC score	0.005657 (rank : 84)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q03395	Gene names	ROM1, TSPAN23
Domain Architecture
Description	Rod outer segment membrane protein 1 (ROSP1) (Tetraspanin-23) (Tspan- 23).

GBP1_HUMAN
NC score	0.005143 (rank : 85)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	339	Shared Neighborhood Hits	3
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

ANGL7_MOUSE
NC score	0.004257 (rank : 86)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1Q3	Gene names	Angptl7
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7).

SHC1_MOUSE
NC score	0.003731 (rank : 87)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	P98083, Q3U2Q7, Q8BFY3, Q8K4C6, Q8K4C7	Gene names	Shc1, Shc, ShcA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

WEE1_MOUSE
NC score	0.003713 (rank : 88)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	794	Shared Neighborhood Hits	5
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

HEM1_HUMAN
NC score	0.003648 (rank : 89)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P13196	Gene names	ALAS1, ALASH
Domain Architecture
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

SHC1_HUMAN
NC score	0.003597 (rank : 90)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	P29353, O15290, Q8N4K5, Q96CL1	Gene names	SHC1, SHC, SHCA
Domain Architecture
Description	SHC-transforming protein 1 (SH2 domain protein C1) (Src homology 2 domain-containing-transforming protein C1).

HS90B_MOUSE
NC score	0.003262 (rank : 91)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

MAP1B_HUMAN
NC score	0.003139 (rank : 92)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	903	Shared Neighborhood Hits	3
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAP1B_MOUSE
NC score	0.002603 (rank : 93)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	977	Shared Neighborhood Hits	4
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

CAD23_HUMAN
NC score	0.000101 (rank : 94)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

LMX1A_HUMAN
NC score	-0.000838 (rank : 95)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	406	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TE12, Q8TE11	Gene names	LMX1A
Domain Architecture
Description	LIM homeobox transcription factor 1 alpha (LIM/homeobox protein LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1).