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Network neighborhood for query Sequence : EXOC2_HUMAN

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EXOC2_HUMAN
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EXOC2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

EXOC2_MOUSE
θ value	0 (rank : 2)	NC score	0.997014 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D4H1	Gene names	Exoc2, Sec5, Sec5l1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

PLXB1_HUMAN
θ value	0.000786445 (rank : 3)	NC score	0.137184 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	360	Shared Neighborhood Hits	8
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PLXB2_HUMAN
θ value	0.00175202 (rank : 4)	NC score	0.133850 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	O15031, Q7KZU3, Q9BSU7	Gene names	PLXNB2, KIAA0315
Domain Architecture	No domain graphic available
Description	Plexin-B2 precursor (MM1).

PLXB1_MOUSE
θ value	0.00509761 (rank : 5)	NC score	0.127547 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	259	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PLXA4_HUMAN
θ value	0.0113563 (rank : 6)	NC score	0.120950 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA4_MOUSE
θ value	0.0113563 (rank : 7)	NC score	0.121189 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA3_HUMAN
θ value	0.0193708 (rank : 8)	NC score	0.119999 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	P51805	Gene names	PLXNA3, PLXN4, SEX
Domain Architecture
Description	Plexin-A3 precursor (Plexin-4) (Semaphorin receptor SEX).

F262_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.038615 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	O60825, O60824, Q9H3P1	Gene names	PFKFB2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

CP135_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.014144 (rank : 38)
Query Neighborhood Hits	34	Target Neighborhood Hits	1278	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

INOC1_MOUSE
θ value	1.81305 (rank : 11)	NC score	0.019180 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

LAMA3_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.017595 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	760	Shared Neighborhood Hits	9
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

F262_MOUSE
θ value	2.36792 (rank : 13)	NC score	0.034195 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P70265, Q8VEI9	Gene names	Pfkfb2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

PRC1_MOUSE
θ value	2.36792 (rank : 14)	NC score	0.039603 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	382	Shared Neighborhood Hits	8
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

VDP_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.017892 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	645	Shared Neighborhood Hits	9
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

BBX_MOUSE
θ value	3.0926 (rank : 16)	NC score	0.023523 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

CB004_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.059642 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y316	Gene names	C2orf4
Domain Architecture
Description	UPF0103 protein C2orf4 (C21orf19-like protein).

CB004_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.059649 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q91VH6	Gene names
Domain Architecture	No domain graphic available
Description	UPF0103 protein C2orf4 homolog.

CK002_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.047456 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UID3, Q6PJV5, Q7L8A6, Q8WZ35, Q96DF4, Q96GR3	Gene names	C11orf2, ANG2
Domain Architecture	No domain graphic available
Description	Protein C11orf2 (Another new gene 2 protein).

DYHC_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.022871 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	733	Shared Neighborhood Hits	8
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	4.03905 (rank : 21)	NC score	0.022875 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	729	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

RIOK2_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.040932 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

IMA2_MOUSE
θ value	5.27518 (rank : 23)	NC score	0.010326 (rank : 40)
Query Neighborhood Hits	34	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

UTP20_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.017562 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

BUD31_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.031862 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	P41223, Q6IB53, Q9UDV1	Gene names	BUD31, EDG2
Domain Architecture
Description	Protein BUD31 homolog (Protein G10 homolog) (EDG-2).

BUD31_MOUSE
θ value	6.88961 (rank : 26)	NC score	0.033210 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PGH1	Gene names	Bud31
Domain Architecture	No domain graphic available
Description	Protein BUD31 homolog (Protein G10 homolog).

NRAP_HUMAN
θ value	6.88961 (rank : 27)	NC score	0.016443 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	Q86VF7, O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059, Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, Q86TE6, Q86VF6, Q8N3R6, Q8N8F9, Q8TCH0, Q96MG4	Gene names	NRAP
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

OLR1_MOUSE
θ value	6.88961 (rank : 28)	NC score	0.013962 (rank : 39)
Query Neighborhood Hits	34	Target Neighborhood Hits	596	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

PSME1_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.027417 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q06323, Q9UEF4	Gene names	PSME1, IFI5111
Domain Architecture
Description	Proteasome activator complex subunit 1 (Proteasome activator 28-alpha subunit) (PA28alpha) (PA28a) (Activator of multicatalytic protease subunit 1) (11S regulator complex subunit alpha) (REG-alpha) (Interferon gamma up-regulated I-5111 protein) (IGUP I-5111).

EPHA2_MOUSE
θ value	8.99809 (rank : 30)	NC score	0.001456 (rank : 43)
Query Neighborhood Hits	34	Target Neighborhood Hits	1020	Shared Neighborhood Hits	3
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

JARD2_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.009488 (rank : 41)
Query Neighborhood Hits	34	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

NRAP_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.015314 (rank : 37)
Query Neighborhood Hits	34	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

PSME1_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.024146 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	P97371, O35561, Q9D841	Gene names	Psme1
Domain Architecture
Description	Proteasome activator complex subunit 1 (Proteasome activator 28-alpha subunit) (PA28alpha) (PA28a) (Activator of multicatalytic protease subunit 1) (11S regulator complex subunit alpha) (REG-alpha).

SYNE2_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.007601 (rank : 42)
Query Neighborhood Hits	34	Target Neighborhood Hits	1323	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

PLXA1_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.090048 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

PLXA1_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.089885 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	P70206, Q5DTR0	Gene names	Plxna1, KIAA4053
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Plexin-1) (Plex 1).

PLXA2_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.089529 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	O75051, Q6UX61, Q96GN9, Q9BRL1, Q9UIW1	Gene names	PLXNA2, KIAA0463, OCT
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Semaphorin receptor OCT).

PLXA2_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.089654 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	P70207, Q6NVE6, Q6PHN4, Q80TZ7, Q8R1I4	Gene names	Plxna2, Kiaa0463
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Plexin-2) (Plex 2).

PLXB3_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.091567 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

PLXB3_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.091728 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	94	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

PLXC1_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.081196 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	O60486, Q59H25	Gene names	PLXNC1, VESPR
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PLXC1_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.081242 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZC2, Q8CGW1	Gene names	Plxnc1, Vespr
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PLXD1_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.091020 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

Hits sorted by NC score

EXOC2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

EXOC2_MOUSE
NC score	0.997014 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D4H1	Gene names	Exoc2, Sec5, Sec5l1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

PLXB1_HUMAN
NC score	0.137184 (rank : 3)	θ value	0.000786445 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	360	Shared Neighborhood Hits	8
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PLXB2_HUMAN
NC score	0.133850 (rank : 4)	θ value	0.00175202 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	O15031, Q7KZU3, Q9BSU7	Gene names	PLXNB2, KIAA0315
Domain Architecture	No domain graphic available
Description	Plexin-B2 precursor (MM1).

PLXB1_MOUSE
NC score	0.127547 (rank : 5)	θ value	0.00509761 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	259	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PLXA4_MOUSE
NC score	0.121189 (rank : 6)	θ value	0.0113563 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA4_HUMAN
NC score	0.120950 (rank : 7)	θ value	0.0113563 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA3_HUMAN
NC score	0.119999 (rank : 8)	θ value	0.0193708 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	P51805	Gene names	PLXNA3, PLXN4, SEX
Domain Architecture
Description	Plexin-A3 precursor (Plexin-4) (Semaphorin receptor SEX).

PLXB3_MOUSE
NC score	0.091728 (rank : 9)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	34	Target Neighborhood Hits	94	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

PLXB3_HUMAN
NC score	0.091567 (rank : 10)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	34	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

PLXD1_HUMAN
NC score	0.091020 (rank : 11)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	34	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

PLXA1_HUMAN
NC score	0.090048 (rank : 12)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

PLXA1_MOUSE
NC score	0.089885 (rank : 13)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	P70206, Q5DTR0	Gene names	Plxna1, KIAA4053
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Plexin-1) (Plex 1).

PLXA2_MOUSE
NC score	0.089654 (rank : 14)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	34	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	P70207, Q6NVE6, Q6PHN4, Q80TZ7, Q8R1I4	Gene names	Plxna2, Kiaa0463
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Plexin-2) (Plex 2).

PLXA2_HUMAN
NC score	0.089529 (rank : 15)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	34	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	O75051, Q6UX61, Q96GN9, Q9BRL1, Q9UIW1	Gene names	PLXNA2, KIAA0463, OCT
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Semaphorin receptor OCT).

PLXC1_MOUSE
NC score	0.081242 (rank : 16)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	34	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZC2, Q8CGW1	Gene names	Plxnc1, Vespr
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PLXC1_HUMAN
NC score	0.081196 (rank : 17)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	34	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	O60486, Q59H25	Gene names	PLXNC1, VESPR
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

CB004_MOUSE
NC score	0.059649 (rank : 18)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q91VH6	Gene names
Domain Architecture	No domain graphic available
Description	UPF0103 protein C2orf4 homolog.

CB004_HUMAN
NC score	0.059642 (rank : 19)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y316	Gene names	C2orf4
Domain Architecture
Description	UPF0103 protein C2orf4 (C21orf19-like protein).

CK002_HUMAN
NC score	0.047456 (rank : 20)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UID3, Q6PJV5, Q7L8A6, Q8WZ35, Q96DF4, Q96GR3	Gene names	C11orf2, ANG2
Domain Architecture	No domain graphic available
Description	Protein C11orf2 (Another new gene 2 protein).

RIOK2_HUMAN
NC score	0.040932 (rank : 21)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

PRC1_MOUSE
NC score	0.039603 (rank : 22)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	382	Shared Neighborhood Hits	8
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

F262_HUMAN
NC score	0.038615 (rank : 23)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	O60825, O60824, Q9H3P1	Gene names	PFKFB2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

F262_MOUSE
NC score	0.034195 (rank : 24)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P70265, Q8VEI9	Gene names	Pfkfb2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

BUD31_MOUSE
NC score	0.033210 (rank : 25)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PGH1	Gene names	Bud31
Domain Architecture	No domain graphic available
Description	Protein BUD31 homolog (Protein G10 homolog).

BUD31_HUMAN
NC score	0.031862 (rank : 26)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	P41223, Q6IB53, Q9UDV1	Gene names	BUD31, EDG2
Domain Architecture
Description	Protein BUD31 homolog (Protein G10 homolog) (EDG-2).

PSME1_HUMAN
NC score	0.027417 (rank : 27)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q06323, Q9UEF4	Gene names	PSME1, IFI5111
Domain Architecture
Description	Proteasome activator complex subunit 1 (Proteasome activator 28-alpha subunit) (PA28alpha) (PA28a) (Activator of multicatalytic protease subunit 1) (11S regulator complex subunit alpha) (REG-alpha) (Interferon gamma up-regulated I-5111 protein) (IGUP I-5111).

PSME1_MOUSE
NC score	0.024146 (rank : 28)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	P97371, O35561, Q9D841	Gene names	Psme1
Domain Architecture
Description	Proteasome activator complex subunit 1 (Proteasome activator 28-alpha subunit) (PA28alpha) (PA28a) (Activator of multicatalytic protease subunit 1) (11S regulator complex subunit alpha) (REG-alpha).

BBX_MOUSE
NC score	0.023523 (rank : 29)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

DYHC_MOUSE
NC score	0.022875 (rank : 30)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	729	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.022871 (rank : 31)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	733	Shared Neighborhood Hits	8
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

INOC1_MOUSE
NC score	0.019180 (rank : 32)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

VDP_HUMAN
NC score	0.017892 (rank : 33)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	645	Shared Neighborhood Hits	9
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

LAMA3_HUMAN
NC score	0.017595 (rank : 34)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	760	Shared Neighborhood Hits	9
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

UTP20_HUMAN
NC score	0.017562 (rank : 35)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

NRAP_HUMAN
NC score	0.016443 (rank : 36)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	Q86VF7, O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059, Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, Q86TE6, Q86VF6, Q8N3R6, Q8N8F9, Q8TCH0, Q96MG4	Gene names	NRAP
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

NRAP_MOUSE
NC score	0.015314 (rank : 37)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

CP135_MOUSE
NC score	0.014144 (rank : 38)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	1278	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

OLR1_MOUSE
NC score	0.013962 (rank : 39)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	596	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

IMA2_MOUSE
NC score	0.010326 (rank : 40)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

JARD2_MOUSE
NC score	0.009488 (rank : 41)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

SYNE2_HUMAN
NC score	0.007601 (rank : 42)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	1323	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

EPHA2_MOUSE
NC score	0.001456 (rank : 43)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	1020	Shared Neighborhood Hits	3
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).