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Network neighborhood for query Sequence : F262_MOUSE

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F262_MOUSE
SwissProt Accessions	P70265, Q8VEI9	Gene names	Pfkfb2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

F262_HUMAN
θ value	0 (rank : 1)	NC score	0.999054 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	O60825, O60824, Q9H3P1	Gene names	PFKFB2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

F262_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	P70265, Q8VEI9	Gene names	Pfkfb2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

F263_HUMAN
θ value	0 (rank : 3)	NC score	0.992989 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q16875, O43622, O75902	Gene names	PFKFB3
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (6PF-2-K/Fru- 2,6-P2ASE brain/placenta-type isozyme) (iPFK-2) (NY-REN-56 antigen) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6- bisphosphatase (EC 3.1.3.46)].

F261_HUMAN
θ value	5.00115e-184 (rank : 4)	NC score	0.992175 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	P16118, Q99951	Gene names	PFKFB1, F6PK, PFRX
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (6PF-2-K/Fru- 2,6-P2ASE liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

F264_HUMAN
θ value	1.11414e-183 (rank : 5)	NC score	0.990585 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q16877	Gene names	PFKFB4
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (6PF-2-K/Fru- 2,6-P2ASE testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

CN37_HUMAN
θ value	0.21417 (rank : 6)	NC score	0.101216 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	P09543	Gene names	CNP
Domain Architecture
Description	2',3'-cyclic-nucleotide 3'-phosphodiesterase (EC 3.1.4.37) (CNP) (CNPase).

CN37_MOUSE
θ value	1.06291 (rank : 7)	NC score	0.083863 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	P16330, Q61424, Q8C7C9, Q91V42, Q923F3	Gene names	Cnp, Cnp1
Domain Architecture
Description	2',3'-cyclic-nucleotide 3'-phosphodiesterase (EC 3.1.4.37) (CNP) (CNPase).

PGAM2_MOUSE
θ value	1.06291 (rank : 8)	NC score	0.077446 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O70250	Gene names	Pgam2
Domain Architecture
Description	Phosphoglycerate mutase 2 (EC 5.4.2.1) (EC 5.4.2.4) (EC 3.1.3.13) (Phosphoglycerate mutase isozyme M) (PGAM-M) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase).

PGAM2_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.075238 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	P15259	Gene names	PGAM2, PGAMM
Domain Architecture
Description	Phosphoglycerate mutase 2 (EC 5.4.2.1) (EC 5.4.2.4) (EC 3.1.3.13) (Phosphoglycerate mutase isozyme M) (PGAM-M) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase).

EXOC2_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.034195 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

ARF6_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.019548 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	255	Shared Neighborhood Hits	5
SwissProt Accessions	P62330, P26438	Gene names	ARF6
Domain Architecture
Description	ADP-ribosylation factor 6.

ARF6_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.019548 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	255	Shared Neighborhood Hits	5
SwissProt Accessions	P62331, P26438	Gene names	Arf6
Domain Architecture
Description	ADP-ribosylation factor 6.

PGAM1_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.078551 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	P18669, Q9BWC0	Gene names	PGAM1
Domain Architecture
Description	Phosphoglycerate mutase 1 (EC 5.4.2.1) (EC 5.4.2.4) (EC 3.1.3.13) (Phosphoglycerate mutase isozyme B) (PGAM-B) (BPG-dependent PGAM 1).

PGAM1_MOUSE
θ value	3.0926 (rank : 14)	NC score	0.078538 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DBJ1, Q9D6W0, Q9ERT3	Gene names	Pgam1
Domain Architecture
Description	Phosphoglycerate mutase 1 (EC 5.4.2.1) (EC 5.4.2.4) (EC 3.1.3.13) (Phosphoglycerate mutase isozyme B) (PGAM-B) (BPG-dependent PGAM 1).

DCTN4_MOUSE
θ value	4.03905 (rank : 15)	NC score	0.018055 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CBY8, Q923A0, Q9D4X0	Gene names	Dctn4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

SPT16_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.024588 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5B9, Q6GMT8, Q6P2F1, Q6PJM1, Q9NRX0	Gene names	SUPT16H, FACT140, FACTP140
Domain Architecture	No domain graphic available
Description	FACT complex subunit SPT16 (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) (FACT 140 kDa subunit) (FACTp140) (Chromatin-specific transcription elongation factor 140 kDa subunit).

SPT16_MOUSE
θ value	4.03905 (rank : 17)	NC score	0.024714 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q920B9, Q3TZ48, Q3UFH0, Q921H4	Gene names	Supt16h, Fact140, Factp140
Domain Architecture	No domain graphic available
Description	FACT complex subunit SPT16 (Facilitates chromatin transcription complex subunit SPT16) (FACT 140 kDa subunit) (FACTp140) (Chromatin- specific transcription elongation factor 140 kDa subunit).

YLPM1_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.023844 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	670	Shared Neighborhood Hits	6
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YLPM1_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.024406 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	505	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

CENA2_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.006314 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

ORCT4_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.010422 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y267, Q6DJT3	Gene names	SLC22A14, ORCTL4
Domain Architecture	No domain graphic available
Description	Organic-cation transporter-like 4 (Solute carrier family 22 member 14).

RRFM_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.026144 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q96E11, Q5RKT1, Q5T7T0, Q5T7T1, Q5T7T2, Q5T7T3, Q5T7T4, Q5T7T5	Gene names	MRRF
Domain Architecture	No domain graphic available
Description	Ribosome recycling factor, mitochondrial precursor.

XAB1_MOUSE
θ value	8.99809 (rank : 23)	NC score	0.024902 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCE2	Gene names	Xab1, Mbdin
Domain Architecture
Description	XPA-binding protein 1.

Hits sorted by NC score

F262_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	P70265, Q8VEI9	Gene names	Pfkfb2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

F262_HUMAN
NC score	0.999054 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	O60825, O60824, Q9H3P1	Gene names	PFKFB2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

F263_HUMAN
NC score	0.992989 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q16875, O43622, O75902	Gene names	PFKFB3
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (6PF-2-K/Fru- 2,6-P2ASE brain/placenta-type isozyme) (iPFK-2) (NY-REN-56 antigen) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6- bisphosphatase (EC 3.1.3.46)].

F261_HUMAN
NC score	0.992175 (rank : 4)	θ value	5.00115e-184 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	P16118, Q99951	Gene names	PFKFB1, F6PK, PFRX
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (6PF-2-K/Fru- 2,6-P2ASE liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

F264_HUMAN
NC score	0.990585 (rank : 5)	θ value	1.11414e-183 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q16877	Gene names	PFKFB4
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (6PF-2-K/Fru- 2,6-P2ASE testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

CN37_HUMAN
NC score	0.101216 (rank : 6)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	P09543	Gene names	CNP
Domain Architecture
Description	2',3'-cyclic-nucleotide 3'-phosphodiesterase (EC 3.1.4.37) (CNP) (CNPase).

CN37_MOUSE
NC score	0.083863 (rank : 7)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	P16330, Q61424, Q8C7C9, Q91V42, Q923F3	Gene names	Cnp, Cnp1
Domain Architecture
Description	2',3'-cyclic-nucleotide 3'-phosphodiesterase (EC 3.1.4.37) (CNP) (CNPase).

PGAM1_HUMAN
NC score	0.078551 (rank : 8)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	P18669, Q9BWC0	Gene names	PGAM1
Domain Architecture
Description	Phosphoglycerate mutase 1 (EC 5.4.2.1) (EC 5.4.2.4) (EC 3.1.3.13) (Phosphoglycerate mutase isozyme B) (PGAM-B) (BPG-dependent PGAM 1).

PGAM1_MOUSE
NC score	0.078538 (rank : 9)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DBJ1, Q9D6W0, Q9ERT3	Gene names	Pgam1
Domain Architecture
Description	Phosphoglycerate mutase 1 (EC 5.4.2.1) (EC 5.4.2.4) (EC 3.1.3.13) (Phosphoglycerate mutase isozyme B) (PGAM-B) (BPG-dependent PGAM 1).

PGAM2_MOUSE
NC score	0.077446 (rank : 10)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O70250	Gene names	Pgam2
Domain Architecture
Description	Phosphoglycerate mutase 2 (EC 5.4.2.1) (EC 5.4.2.4) (EC 3.1.3.13) (Phosphoglycerate mutase isozyme M) (PGAM-M) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase).

PGAM2_HUMAN
NC score	0.075238 (rank : 11)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	P15259	Gene names	PGAM2, PGAMM
Domain Architecture
Description	Phosphoglycerate mutase 2 (EC 5.4.2.1) (EC 5.4.2.4) (EC 3.1.3.13) (Phosphoglycerate mutase isozyme M) (PGAM-M) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase).

EXOC2_HUMAN
NC score	0.034195 (rank : 12)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

RRFM_HUMAN
NC score	0.026144 (rank : 13)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q96E11, Q5RKT1, Q5T7T0, Q5T7T1, Q5T7T2, Q5T7T3, Q5T7T4, Q5T7T5	Gene names	MRRF
Domain Architecture	No domain graphic available
Description	Ribosome recycling factor, mitochondrial precursor.

XAB1_MOUSE
NC score	0.024902 (rank : 14)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCE2	Gene names	Xab1, Mbdin
Domain Architecture
Description	XPA-binding protein 1.

SPT16_MOUSE
NC score	0.024714 (rank : 15)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q920B9, Q3TZ48, Q3UFH0, Q921H4	Gene names	Supt16h, Fact140, Factp140
Domain Architecture	No domain graphic available
Description	FACT complex subunit SPT16 (Facilitates chromatin transcription complex subunit SPT16) (FACT 140 kDa subunit) (FACTp140) (Chromatin- specific transcription elongation factor 140 kDa subunit).

SPT16_HUMAN
NC score	0.024588 (rank : 16)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5B9, Q6GMT8, Q6P2F1, Q6PJM1, Q9NRX0	Gene names	SUPT16H, FACT140, FACTP140
Domain Architecture	No domain graphic available
Description	FACT complex subunit SPT16 (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) (FACT 140 kDa subunit) (FACTp140) (Chromatin-specific transcription elongation factor 140 kDa subunit).

YLPM1_MOUSE
NC score	0.024406 (rank : 17)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	505	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

YLPM1_HUMAN
NC score	0.023844 (rank : 18)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	670	Shared Neighborhood Hits	6
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ARF6_HUMAN
NC score	0.019548 (rank : 19)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	255	Shared Neighborhood Hits	5
SwissProt Accessions	P62330, P26438	Gene names	ARF6
Domain Architecture
Description	ADP-ribosylation factor 6.

ARF6_MOUSE
NC score	0.019548 (rank : 20)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	255	Shared Neighborhood Hits	5
SwissProt Accessions	P62331, P26438	Gene names	Arf6
Domain Architecture
Description	ADP-ribosylation factor 6.

DCTN4_MOUSE
NC score	0.018055 (rank : 21)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CBY8, Q923A0, Q9D4X0	Gene names	Dctn4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

ORCT4_HUMAN
NC score	0.010422 (rank : 22)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y267, Q6DJT3	Gene names	SLC22A14, ORCTL4
Domain Architecture	No domain graphic available
Description	Organic-cation transporter-like 4 (Solute carrier family 22 member 14).

CENA2_MOUSE
NC score	0.006314 (rank : 23)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.