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Network neighborhood for query Sequence : CN37_HUMAN

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CN37_HUMAN
SwissProt Accessions	P09543	Gene names	CNP
Domain Architecture
Description	2',3'-cyclic-nucleotide 3'-phosphodiesterase (EC 3.1.4.37) (CNP) (CNPase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CN37_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P09543	Gene names	CNP
Domain Architecture
Description	2',3'-cyclic-nucleotide 3'-phosphodiesterase (EC 3.1.4.37) (CNP) (CNPase).

CN37_MOUSE
θ value	0 (rank : 2)	NC score	0.996777 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	P16330, Q61424, Q8C7C9, Q91V42, Q923F3	Gene names	Cnp, Cnp1
Domain Architecture
Description	2',3'-cyclic-nucleotide 3'-phosphodiesterase (EC 3.1.4.37) (CNP) (CNPase).

N4BP2_HUMAN
θ value	9.29e-05 (rank : 3)	NC score	0.261259 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

F262_HUMAN
θ value	0.0431538 (rank : 4)	NC score	0.112620 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	O60825, O60824, Q9H3P1	Gene names	PFKFB2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

F262_MOUSE
θ value	0.21417 (rank : 5)	NC score	0.101216 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	P70265, Q8VEI9	Gene names	Pfkfb2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

YLPM1_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.061759 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	670	Shared Neighborhood Hits	7
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

F264_HUMAN
θ value	1.06291 (rank : 7)	NC score	0.089180 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q16877	Gene names	PFKFB4
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (6PF-2-K/Fru- 2,6-P2ASE testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

TBE_HUMAN
θ value	1.38821 (rank : 8)	NC score	0.034607 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJT0, Q8NEG3	Gene names	TUBE1, TUBE
Domain Architecture
Description	Tubulin epsilon chain (Epsilon tubulin).

KAD5_HUMAN
θ value	1.81305 (rank : 9)	NC score	0.051583 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6K8, Q96EC9	Gene names	AK5
Domain Architecture
Description	Adenylate kinase isoenzyme 5 (EC 2.7.4.3) (ATP-AMP transphosphorylase).

TBE_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.031730 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D6T1	Gene names	Tube1
Domain Architecture	No domain graphic available
Description	Tubulin epsilon chain (Epsilon tubulin).

YLPM1_MOUSE
θ value	3.0926 (rank : 11)	NC score	0.065643 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	505	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

M3K9_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.001958 (rank : 17)
Query Neighborhood Hits	15	Target Neighborhood Hits	1123	Shared Neighborhood Hits	2
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

TM16B_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.013316 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQ90	Gene names	TMEM16B, C12orf3
Domain Architecture
Description	Transmembrane protein 16B.

KAD5_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.036338 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q920P5	Gene names	Ak5
Domain Architecture
Description	Adenylate kinase isoenzyme 5 (EC 2.7.4.3) (ATP-AMP transphosphorylase).

VP33A_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.012933 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q96AX1, Q9H5Q0	Gene names	VPS33A
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A (hVPS33A).

F261_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.060766 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P16118, Q99951	Gene names	PFKFB1, F6PK, PFRX
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (6PF-2-K/Fru- 2,6-P2ASE liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

F263_HUMAN
θ value	θ > 10 (rank : 17)	NC score	0.060833 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q16875, O43622, O75902	Gene names	PFKFB3
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (6PF-2-K/Fru- 2,6-P2ASE brain/placenta-type isozyme) (iPFK-2) (NY-REN-56 antigen) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6- bisphosphatase (EC 3.1.3.46)].

Hits sorted by NC score

CN37_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P09543	Gene names	CNP
Domain Architecture
Description	2',3'-cyclic-nucleotide 3'-phosphodiesterase (EC 3.1.4.37) (CNP) (CNPase).

CN37_MOUSE
NC score	0.996777 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	P16330, Q61424, Q8C7C9, Q91V42, Q923F3	Gene names	Cnp, Cnp1
Domain Architecture
Description	2',3'-cyclic-nucleotide 3'-phosphodiesterase (EC 3.1.4.37) (CNP) (CNPase).

N4BP2_HUMAN
NC score	0.261259 (rank : 3)	θ value	9.29e-05 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

F262_HUMAN
NC score	0.112620 (rank : 4)	θ value	0.0431538 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	22	Shared Neighborhood Hits	7
SwissProt Accessions	O60825, O60824, Q9H3P1	Gene names	PFKFB2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

F262_MOUSE
NC score	0.101216 (rank : 5)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	P70265, Q8VEI9	Gene names	Pfkfb2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

F264_HUMAN
NC score	0.089180 (rank : 6)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q16877	Gene names	PFKFB4
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (6PF-2-K/Fru- 2,6-P2ASE testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

YLPM1_MOUSE
NC score	0.065643 (rank : 7)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	505	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

YLPM1_HUMAN
NC score	0.061759 (rank : 8)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	670	Shared Neighborhood Hits	7
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

F263_HUMAN
NC score	0.060833 (rank : 9)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q16875, O43622, O75902	Gene names	PFKFB3
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (6PF-2-K/Fru- 2,6-P2ASE brain/placenta-type isozyme) (iPFK-2) (NY-REN-56 antigen) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6- bisphosphatase (EC 3.1.3.46)].

F261_HUMAN
NC score	0.060766 (rank : 10)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P16118, Q99951	Gene names	PFKFB1, F6PK, PFRX
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (6PF-2-K/Fru- 2,6-P2ASE liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

KAD5_HUMAN
NC score	0.051583 (rank : 11)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6K8, Q96EC9	Gene names	AK5
Domain Architecture
Description	Adenylate kinase isoenzyme 5 (EC 2.7.4.3) (ATP-AMP transphosphorylase).

KAD5_MOUSE
NC score	0.036338 (rank : 12)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q920P5	Gene names	Ak5
Domain Architecture
Description	Adenylate kinase isoenzyme 5 (EC 2.7.4.3) (ATP-AMP transphosphorylase).

TBE_HUMAN
NC score	0.034607 (rank : 13)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJT0, Q8NEG3	Gene names	TUBE1, TUBE
Domain Architecture
Description	Tubulin epsilon chain (Epsilon tubulin).

TBE_MOUSE
NC score	0.031730 (rank : 14)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D6T1	Gene names	Tube1
Domain Architecture	No domain graphic available
Description	Tubulin epsilon chain (Epsilon tubulin).

TM16B_HUMAN
NC score	0.013316 (rank : 15)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQ90	Gene names	TMEM16B, C12orf3
Domain Architecture
Description	Transmembrane protein 16B.

VP33A_HUMAN
NC score	0.012933 (rank : 16)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q96AX1, Q9H5Q0	Gene names	VPS33A
Domain Architecture
Description	Vacuolar protein sorting-associated protein 33A (hVPS33A).

M3K9_HUMAN
NC score	0.001958 (rank : 17)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	1123	Shared Neighborhood Hits	2
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).