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Network neighborhood for query Sequence : DCTN4_MOUSE

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DCTN4_MOUSE
SwissProt Accessions	Q8CBY8, Q923A0, Q9D4X0	Gene names	Dctn4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DCTN4_HUMAN
θ value	0 (rank : 1)	NC score	0.998323 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UJW0, Q8TAN8	Gene names	DCTN4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

DCTN4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CBY8, Q923A0, Q9D4X0	Gene names	Dctn4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

STIP1_MOUSE
θ value	0.163984 (rank : 3)	NC score	0.073897 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

STIP1_HUMAN
θ value	0.813845 (rank : 4)	NC score	0.063672 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	P31948	Gene names	STIP1
Domain Architecture
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY- REN-11 antigen).

TF2H2_MOUSE
θ value	0.813845 (rank : 5)	NC score	0.089788 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIB4	Gene names	Gtf2h2, Btf2p44
Domain Architecture
Description	TFIIH basal transcription factor complex p44 subunit (Basic transcription factor 2 44 kDa subunit) (BTF2-p44) (General transcription factor IIH polypeptide 2).

TF2H2_HUMAN
θ value	1.06291 (rank : 6)	NC score	0.086122 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q13888, Q15570, Q15571, Q9BS41	Gene names	GTF2H2, BTF2P44
Domain Architecture
Description	TFIIH basal transcription factor complex p44 subunit (Basic transcription factor 2 44 kDa subunit) (BTF2-p44) (General transcription factor IIH polypeptide 2).

UHRF2_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.039219 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	269	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

ICAM2_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.037857 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P13598, Q14600	Gene names	ICAM2
Domain Architecture
Description	Intercellular adhesion molecule 2 precursor (ICAM-2) (CD102 antigen).

NID1_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.010554 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	329	Shared Neighborhood Hits	3
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

S3TC1_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.037915 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

F262_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.018055 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P70265, Q8VEI9	Gene names	Pfkfb2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

FYV1_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.016964 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	217	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

ARBK1_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.004095 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	859	Shared Neighborhood Hits	3
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

UHRF2_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.029014 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	275	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

PCSK5_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.009535 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	613	Shared Neighborhood Hits	4
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

AKAP3_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.018580 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	O88987	Gene names	Akap3, Akap110
Domain Architecture
Description	A-kinase anchor protein 3 (Protein kinase A-anchoring protein 3) (PRKA3) (A-kinase anchor protein 110 kDa) (AKAP 110).

EXT1_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.019414 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q16394, Q9BVI9	Gene names	EXT1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1).

EXT1_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.019408 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P97464, Q61546	Gene names	Ext1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog).

K0586_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.014985 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	311	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

ZN408_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.001096 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	775	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).

Hits sorted by NC score

DCTN4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CBY8, Q923A0, Q9D4X0	Gene names	Dctn4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

DCTN4_HUMAN
NC score	0.998323 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UJW0, Q8TAN8	Gene names	DCTN4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

TF2H2_MOUSE
NC score	0.089788 (rank : 3)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIB4	Gene names	Gtf2h2, Btf2p44
Domain Architecture
Description	TFIIH basal transcription factor complex p44 subunit (Basic transcription factor 2 44 kDa subunit) (BTF2-p44) (General transcription factor IIH polypeptide 2).

TF2H2_HUMAN
NC score	0.086122 (rank : 4)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q13888, Q15570, Q15571, Q9BS41	Gene names	GTF2H2, BTF2P44
Domain Architecture
Description	TFIIH basal transcription factor complex p44 subunit (Basic transcription factor 2 44 kDa subunit) (BTF2-p44) (General transcription factor IIH polypeptide 2).

STIP1_MOUSE
NC score	0.073897 (rank : 5)	θ value	0.163984 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

STIP1_HUMAN
NC score	0.063672 (rank : 6)	θ value	0.813845 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	P31948	Gene names	STIP1
Domain Architecture
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY- REN-11 antigen).

UHRF2_HUMAN
NC score	0.039219 (rank : 7)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	269	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

S3TC1_HUMAN
NC score	0.037915 (rank : 8)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

ICAM2_HUMAN
NC score	0.037857 (rank : 9)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P13598, Q14600	Gene names	ICAM2
Domain Architecture
Description	Intercellular adhesion molecule 2 precursor (ICAM-2) (CD102 antigen).

UHRF2_MOUSE
NC score	0.029014 (rank : 10)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	275	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

EXT1_HUMAN
NC score	0.019414 (rank : 11)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q16394, Q9BVI9	Gene names	EXT1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1).

EXT1_MOUSE
NC score	0.019408 (rank : 12)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P97464, Q61546	Gene names	Ext1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog).

AKAP3_MOUSE
NC score	0.018580 (rank : 13)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	O88987	Gene names	Akap3, Akap110
Domain Architecture
Description	A-kinase anchor protein 3 (Protein kinase A-anchoring protein 3) (PRKA3) (A-kinase anchor protein 110 kDa) (AKAP 110).

F262_MOUSE
NC score	0.018055 (rank : 14)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P70265, Q8VEI9	Gene names	Pfkfb2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

FYV1_HUMAN
NC score	0.016964 (rank : 15)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	217	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

K0586_HUMAN
NC score	0.014985 (rank : 16)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	311	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

NID1_HUMAN
NC score	0.010554 (rank : 17)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	329	Shared Neighborhood Hits	3
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

PCSK5_MOUSE
NC score	0.009535 (rank : 18)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	613	Shared Neighborhood Hits	4
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

ARBK1_HUMAN
NC score	0.004095 (rank : 19)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	859	Shared Neighborhood Hits	3
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

ZN408_HUMAN
NC score	0.001096 (rank : 20)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	775	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H9D4	Gene names	ZNF408, PFM14, PRDM17
Domain Architecture	No domain graphic available
Description	Zinc finger protein 408 (PR-domain zinc finger protein 17).