Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : PCSK5_MOUSE

For an explanation of this page, click here

PCSK5_MOUSE
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FURIN_HUMAN
θ value	0 (rank : 1)	NC score	0.743338 (rank : 5)
Query Neighborhood Hits	613	Target Neighborhood Hits	52	Shared Neighborhood Hits	43
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

FURIN_MOUSE
θ value	0 (rank : 2)	NC score	0.745217 (rank : 4)
Query Neighborhood Hits	613	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

PCSK5_HUMAN
θ value	0 (rank : 3)	NC score	0.907094 (rank : 2)
Query Neighborhood Hits	613	Target Neighborhood Hits	291	Shared Neighborhood Hits	270
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK5_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	613	Target Neighborhood Hits	613	Shared Neighborhood Hits	613
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK6_HUMAN
θ value	0 (rank : 5)	NC score	0.883122 (rank : 3)
Query Neighborhood Hits	613	Target Neighborhood Hits	298	Shared Neighborhood Hits	217
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PCSK4_HUMAN
θ value	2.17943e-171 (rank : 6)	NC score	0.731285 (rank : 6)
Query Neighborhood Hits	613	Target Neighborhood Hits	32	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

NEC1_HUMAN
θ value	1.79118e-157 (rank : 7)	NC score	0.711155 (rank : 9)
Query Neighborhood Hits	613	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P29120, P78478, Q92532	Gene names	PCSK1, NEC1
Domain Architecture
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1).

PCSK4_MOUSE
θ value	5.21151e-157 (rank : 8)	NC score	0.714243 (rank : 7)
Query Neighborhood Hits	613	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

NEC1_MOUSE
θ value	9.82853e-156 (rank : 9)	NC score	0.711170 (rank : 8)
Query Neighborhood Hits	613	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	P63239, P21662, P22546	Gene names	Pcsk1, Att-1, Nec-1, Nec1
Domain Architecture	No domain graphic available
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1) (PC3) (Furin homolog) (Propeptide-processing protease).

NEC2_MOUSE
θ value	2.51683e-135 (rank : 10)	NC score	0.708210 (rank : 10)
Query Neighborhood Hits	613	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	P21661, Q80WU1	Gene names	Pcsk2, Nec-2, Nec2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

NEC2_HUMAN
θ value	1.24909e-134 (rank : 11)	NC score	0.707977 (rank : 11)
Query Neighborhood Hits	613	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	P16519, Q14927, Q9NQG3, Q9NUG1, Q9UJC6	Gene names	PCSK2, NEC2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

PCSK7_MOUSE
θ value	5.8157e-124 (rank : 12)	NC score	0.702832 (rank : 12)
Query Neighborhood Hits	613	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

PCSK7_HUMAN
θ value	8.39787e-123 (rank : 13)	NC score	0.702830 (rank : 13)
Query Neighborhood Hits	613	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

FRAS1_MOUSE
θ value	2.08291e-97 (rank : 14)	NC score	0.561484 (rank : 16)
Query Neighborhood Hits	613	Target Neighborhood Hits	747	Shared Neighborhood Hits	411
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_HUMAN
θ value	7.66637e-92 (rank : 15)	NC score	0.569425 (rank : 14)
Query Neighborhood Hits	613	Target Neighborhood Hits	759	Shared Neighborhood Hits	415
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MEGF6_HUMAN
θ value	1.33217e-27 (rank : 16)	NC score	0.566816 (rank : 15)
Query Neighborhood Hits	613	Target Neighborhood Hits	671	Shared Neighborhood Hits	402
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

ZAN_MOUSE
θ value	4.28545e-26 (rank : 17)	NC score	0.491622 (rank : 30)
Query Neighborhood Hits	613	Target Neighborhood Hits	808	Shared Neighborhood Hits	388
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

NOTC1_MOUSE
θ value	5.07402e-19 (rank : 18)	NC score	0.470368 (rank : 44)
Query Neighborhood Hits	613	Target Neighborhood Hits	916	Shared Neighborhood Hits	344
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LTBP2_MOUSE
θ value	9.56915e-18 (rank : 19)	NC score	0.485409 (rank : 33)
Query Neighborhood Hits	613	Target Neighborhood Hits	617	Shared Neighborhood Hits	312
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBN1_HUMAN
θ value	1.63225e-17 (rank : 20)	NC score	0.495134 (rank : 25)
Query Neighborhood Hits	613	Target Neighborhood Hits	557	Shared Neighborhood Hits	353
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

NOTC1_HUMAN
θ value	1.38178e-16 (rank : 21)	NC score	0.457080 (rank : 52)
Query Neighborhood Hits	613	Target Neighborhood Hits	906	Shared Neighborhood Hits	346
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SREC_HUMAN
θ value	4.02038e-16 (rank : 22)	NC score	0.558397 (rank : 17)
Query Neighborhood Hits	613	Target Neighborhood Hits	645	Shared Neighborhood Hits	364
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

FBN1_MOUSE
θ value	1.52774e-15 (rank : 23)	NC score	0.493866 (rank : 27)
Query Neighborhood Hits	613	Target Neighborhood Hits	563	Shared Neighborhood Hits	352
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

NOTC3_HUMAN
θ value	1.52774e-15 (rank : 24)	NC score	0.452026 (rank : 59)
Query Neighborhood Hits	613	Target Neighborhood Hits	1062	Shared Neighborhood Hits	345
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FBN2_MOUSE
θ value	2.60593e-15 (rank : 25)	NC score	0.490365 (rank : 31)
Query Neighborhood Hits	613	Target Neighborhood Hits	549	Shared Neighborhood Hits	357
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LTBP2_HUMAN
θ value	4.44505e-15 (rank : 26)	NC score	0.479997 (rank : 36)
Query Neighborhood Hits	613	Target Neighborhood Hits	552	Shared Neighborhood Hits	317
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBN2_HUMAN
θ value	1.29331e-14 (rank : 27)	NC score	0.494051 (rank : 26)
Query Neighborhood Hits	613	Target Neighborhood Hits	560	Shared Neighborhood Hits	349
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

SREC2_HUMAN
θ value	2.88119e-14 (rank : 28)	NC score	0.546023 (rank : 19)
Query Neighborhood Hits	613	Target Neighborhood Hits	645	Shared Neighborhood Hits	347
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LAMA1_MOUSE
θ value	3.76295e-14 (rank : 29)	NC score	0.445897 (rank : 69)
Query Neighborhood Hits	613	Target Neighborhood Hits	838	Shared Neighborhood Hits	347
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NOTC3_MOUSE
θ value	4.91457e-14 (rank : 30)	NC score	0.449894 (rank : 65)
Query Neighborhood Hits	613	Target Neighborhood Hits	975	Shared Neighborhood Hits	347
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_MOUSE
θ value	6.41864e-14 (rank : 31)	NC score	0.443727 (rank : 72)
Query Neighborhood Hits	613	Target Neighborhood Hits	1069	Shared Neighborhood Hits	340
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

FBN3_HUMAN
θ value	1.09485e-13 (rank : 32)	NC score	0.493541 (rank : 28)
Query Neighborhood Hits	613	Target Neighborhood Hits	543	Shared Neighborhood Hits	343
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LAMA1_HUMAN
θ value	1.09485e-13 (rank : 33)	NC score	0.443816 (rank : 71)
Query Neighborhood Hits	613	Target Neighborhood Hits	804	Shared Neighborhood Hits	351
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC3_HUMAN
θ value	1.42992e-13 (rank : 34)	NC score	0.441985 (rank : 77)
Query Neighborhood Hits	613	Target Neighborhood Hits	588	Shared Neighborhood Hits	325
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

NOTC2_HUMAN
θ value	1.42992e-13 (rank : 35)	NC score	0.442145 (rank : 76)
Query Neighborhood Hits	613	Target Neighborhood Hits	1113	Shared Neighborhood Hits	352
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

LAMA5_HUMAN
θ value	2.43908e-13 (rank : 36)	NC score	0.457014 (rank : 53)
Query Neighborhood Hits	613	Target Neighborhood Hits	976	Shared Neighborhood Hits	366
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

SREC2_MOUSE
θ value	3.18553e-13 (rank : 37)	NC score	0.552298 (rank : 18)
Query Neighborhood Hits	613	Target Neighborhood Hits	605	Shared Neighborhood Hits	348
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

MEGF9_MOUSE
θ value	7.09661e-13 (rank : 38)	NC score	0.477842 (rank : 37)
Query Neighborhood Hits	613	Target Neighborhood Hits	896	Shared Neighborhood Hits	295
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NOTC4_HUMAN
θ value	1.2105e-12 (rank : 39)	NC score	0.441606 (rank : 79)
Query Neighborhood Hits	613	Target Neighborhood Hits	905	Shared Neighborhood Hits	347
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TENX_HUMAN
θ value	1.58096e-12 (rank : 40)	NC score	0.406180 (rank : 114)
Query Neighborhood Hits	613	Target Neighborhood Hits	789	Shared Neighborhood Hits	333
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

USH2A_MOUSE
θ value	2.69671e-12 (rank : 41)	NC score	0.412504 (rank : 106)
Query Neighborhood Hits	613	Target Neighborhood Hits	626	Shared Neighborhood Hits	317
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

ERBB4_HUMAN
θ value	3.52202e-12 (rank : 42)	NC score	0.105745 (rank : 476)
Query Neighborhood Hits	613	Target Neighborhood Hits	910	Shared Neighborhood Hits	103
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

MEGF9_HUMAN
θ value	6.00763e-12 (rank : 43)	NC score	0.495187 (rank : 24)
Query Neighborhood Hits	613	Target Neighborhood Hits	557	Shared Neighborhood Hits	298
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MATN2_HUMAN
θ value	1.02475e-11 (rank : 44)	NC score	0.411164 (rank : 107)
Query Neighborhood Hits	613	Target Neighborhood Hits	365	Shared Neighborhood Hits	232
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

RSPO1_HUMAN
θ value	1.33837e-11 (rank : 45)	NC score	0.303110 (rank : 219)
Query Neighborhood Hits	613	Target Neighborhood Hits	101	Shared Neighborhood Hits	76
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

ERBB3_HUMAN
θ value	1.74796e-11 (rank : 46)	NC score	0.119184 (rank : 445)
Query Neighborhood Hits	613	Target Neighborhood Hits	918	Shared Neighborhood Hits	124
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

MATN2_MOUSE
θ value	3.89403e-11 (rank : 47)	NC score	0.404835 (rank : 116)
Query Neighborhood Hits	613	Target Neighborhood Hits	356	Shared Neighborhood Hits	226
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

NOTC4_MOUSE
θ value	3.89403e-11 (rank : 48)	NC score	0.436191 (rank : 85)
Query Neighborhood Hits	613	Target Neighborhood Hits	872	Shared Neighborhood Hits	338
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

LAMB2_MOUSE
θ value	5.08577e-11 (rank : 49)	NC score	0.441845 (rank : 78)
Query Neighborhood Hits	613	Target Neighborhood Hits	722	Shared Neighborhood Hits	311
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

FBLN2_HUMAN
θ value	6.64225e-11 (rank : 50)	NC score	0.445634 (rank : 70)
Query Neighborhood Hits	613	Target Neighborhood Hits	392	Shared Neighborhood Hits	253
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LAMA2_MOUSE
θ value	6.64225e-11 (rank : 51)	NC score	0.389678 (rank : 129)
Query Neighborhood Hits	613	Target Neighborhood Hits	1198	Shared Neighborhood Hits	339
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA5_MOUSE
θ value	6.64225e-11 (rank : 52)	NC score	0.465297 (rank : 48)
Query Neighborhood Hits	613	Target Neighborhood Hits	828	Shared Neighborhood Hits	369
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LRP1_HUMAN
θ value	6.64225e-11 (rank : 53)	NC score	0.400591 (rank : 120)
Query Neighborhood Hits	613	Target Neighborhood Hits	617	Shared Neighborhood Hits	353
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

RSPO1_MOUSE
θ value	8.67504e-11 (rank : 54)	NC score	0.282752 (rank : 244)
Query Neighborhood Hits	613	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

LAMB2_HUMAN
θ value	1.133e-10 (rank : 55)	NC score	0.448994 (rank : 66)
Query Neighborhood Hits	613	Target Neighborhood Hits	692	Shared Neighborhood Hits	317
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

TENA_HUMAN
θ value	1.133e-10 (rank : 56)	NC score	0.407312 (rank : 113)
Query Neighborhood Hits	613	Target Neighborhood Hits	631	Shared Neighborhood Hits	312
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

ERBB2_MOUSE
θ value	1.47974e-10 (rank : 57)	NC score	0.100063 (rank : 496)
Query Neighborhood Hits	613	Target Neighborhood Hits	918	Shared Neighborhood Hits	91
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_MOUSE
θ value	1.9326e-10 (rank : 58)	NC score	0.115391 (rank : 455)
Query Neighborhood Hits	613	Target Neighborhood Hits	898	Shared Neighborhood Hits	108
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

CREL1_MOUSE
θ value	2.52405e-10 (rank : 59)	NC score	0.525336 (rank : 21)
Query Neighborhood Hits	613	Target Neighborhood Hits	524	Shared Neighborhood Hits	311
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LTB1L_HUMAN
θ value	2.52405e-10 (rank : 60)	NC score	0.455896 (rank : 54)
Query Neighborhood Hits	613	Target Neighborhood Hits	553	Shared Neighborhood Hits	301
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	2.52405e-10 (rank : 61)	NC score	0.455113 (rank : 55)
Query Neighborhood Hits	613	Target Neighborhood Hits	502	Shared Neighborhood Hits	287
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CREL1_HUMAN
θ value	3.29651e-10 (rank : 62)	NC score	0.530160 (rank : 20)
Query Neighborhood Hits	613	Target Neighborhood Hits	441	Shared Neighborhood Hits	284
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

RSPO3_MOUSE
θ value	3.29651e-10 (rank : 63)	NC score	0.340799 (rank : 171)
Query Neighborhood Hits	613	Target Neighborhood Hits	120	Shared Neighborhood Hits	89
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

TENA_MOUSE
θ value	3.29651e-10 (rank : 64)	NC score	0.397252 (rank : 122)
Query Neighborhood Hits	613	Target Neighborhood Hits	596	Shared Neighborhood Hits	308
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

RSPO4_HUMAN
θ value	4.30538e-10 (rank : 65)	NC score	0.337642 (rank : 177)
Query Neighborhood Hits	613	Target Neighborhood Hits	110	Shared Neighborhood Hits	91
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

MEGF8_HUMAN
θ value	7.34386e-10 (rank : 66)	NC score	0.493405 (rank : 29)
Query Neighborhood Hits	613	Target Neighborhood Hits	528	Shared Neighborhood Hits	324
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	7.34386e-10 (rank : 67)	NC score	0.486188 (rank : 32)
Query Neighborhood Hits	613	Target Neighborhood Hits	520	Shared Neighborhood Hits	311
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

RSPO3_HUMAN
θ value	9.59137e-10 (rank : 68)	NC score	0.351851 (rank : 161)
Query Neighborhood Hits	613	Target Neighborhood Hits	128	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

LAMC3_MOUSE
θ value	1.25267e-09 (rank : 69)	NC score	0.437580 (rank : 82)
Query Neighborhood Hits	613	Target Neighborhood Hits	624	Shared Neighborhood Hits	313
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

EGFR_HUMAN
θ value	2.13673e-09 (rank : 70)	NC score	0.099564 (rank : 498)
Query Neighborhood Hits	613	Target Neighborhood Hits	939	Shared Neighborhood Hits	116
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

LAMB1_HUMAN
θ value	2.13673e-09 (rank : 71)	NC score	0.397187 (rank : 124)
Query Neighborhood Hits	613	Target Neighborhood Hits	1018	Shared Neighborhood Hits	300
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

CRIM1_HUMAN
θ value	3.64472e-09 (rank : 72)	NC score	0.436515 (rank : 84)
Query Neighborhood Hits	613	Target Neighborhood Hits	362	Shared Neighborhood Hits	244
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

RSPO4_MOUSE
θ value	4.76016e-09 (rank : 73)	NC score	0.328735 (rank : 186)
Query Neighborhood Hits	613	Target Neighborhood Hits	110	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

NELL2_MOUSE
θ value	6.21693e-09 (rank : 74)	NC score	0.467197 (rank : 47)
Query Neighborhood Hits	613	Target Neighborhood Hits	436	Shared Neighborhood Hits	290
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

SCUB3_HUMAN
θ value	6.21693e-09 (rank : 75)	NC score	0.457480 (rank : 51)
Query Neighborhood Hits	613	Target Neighborhood Hits	428	Shared Neighborhood Hits	293
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ERBB2_HUMAN
θ value	8.11959e-09 (rank : 76)	NC score	0.100612 (rank : 494)
Query Neighborhood Hits	613	Target Neighborhood Hits	1073	Shared Neighborhood Hits	104
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

LRP2_HUMAN
θ value	8.11959e-09 (rank : 77)	NC score	0.379265 (rank : 138)
Query Neighborhood Hits	613	Target Neighborhood Hits	573	Shared Neighborhood Hits	335
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LAMA2_HUMAN
θ value	1.06045e-08 (rank : 78)	NC score	0.410497 (rank : 110)
Query Neighborhood Hits	613	Target Neighborhood Hits	1092	Shared Neighborhood Hits	351
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

SSPO_MOUSE
θ value	1.06045e-08 (rank : 79)	NC score	0.365113 (rank : 152)
Query Neighborhood Hits	613	Target Neighborhood Hits	800	Shared Neighborhood Hits	372
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

RSPO2_HUMAN
θ value	1.38499e-08 (rank : 80)	NC score	0.312636 (rank : 209)
Query Neighborhood Hits	613	Target Neighborhood Hits	90	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

USH2A_HUMAN
θ value	1.38499e-08 (rank : 81)	NC score	0.380372 (rank : 136)
Query Neighborhood Hits	613	Target Neighborhood Hits	600	Shared Neighborhood Hits	290
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

IGF1R_MOUSE
θ value	2.36244e-08 (rank : 82)	NC score	0.101754 (rank : 489)
Query Neighborhood Hits	613	Target Neighborhood Hits	973	Shared Neighborhood Hits	145
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

RSPO2_MOUSE
θ value	2.36244e-08 (rank : 83)	NC score	0.313401 (rank : 207)
Query Neighborhood Hits	613	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

KRA54_HUMAN
θ value	3.08544e-08 (rank : 84)	NC score	0.472112 (rank : 41)
Query Neighborhood Hits	613	Target Neighborhood Hits	270	Shared Neighborhood Hits	191
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LAMB1_MOUSE
θ value	3.08544e-08 (rank : 85)	NC score	0.414048 (rank : 104)
Query Neighborhood Hits	613	Target Neighborhood Hits	919	Shared Neighborhood Hits	291
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

NELL2_HUMAN
θ value	4.0297e-08 (rank : 86)	NC score	0.468495 (rank : 45)
Query Neighborhood Hits	613	Target Neighborhood Hits	449	Shared Neighborhood Hits	293
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

LAMB3_MOUSE
θ value	5.26297e-08 (rank : 87)	NC score	0.404175 (rank : 118)
Query Neighborhood Hits	613	Target Neighborhood Hits	444	Shared Neighborhood Hits	230
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LTBP4_MOUSE
θ value	8.97725e-08 (rank : 88)	NC score	0.481257 (rank : 35)
Query Neighborhood Hits	613	Target Neighborhood Hits	607	Shared Neighborhood Hits	316
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FBLN1_HUMAN
θ value	1.17247e-07 (rank : 89)	NC score	0.427126 (rank : 94)
Query Neighborhood Hits	613	Target Neighborhood Hits	324	Shared Neighborhood Hits	240
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

LTBP3_MOUSE
θ value	1.17247e-07 (rank : 90)	NC score	0.453932 (rank : 56)
Query Neighborhood Hits	613	Target Neighborhood Hits	475	Shared Neighborhood Hits	300
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBLN5_MOUSE
θ value	1.53129e-07 (rank : 91)	NC score	0.410532 (rank : 109)
Query Neighborhood Hits	613	Target Neighborhood Hits	317	Shared Neighborhood Hits	240
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

IGF1R_HUMAN
θ value	1.53129e-07 (rank : 92)	NC score	0.098759 (rank : 502)
Query Neighborhood Hits	613	Target Neighborhood Hits	977	Shared Neighborhood Hits	147
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

JAG2_MOUSE
θ value	1.53129e-07 (rank : 93)	NC score	0.464529 (rank : 49)
Query Neighborhood Hits	613	Target Neighborhood Hits	504	Shared Neighborhood Hits	310
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

FBLN2_MOUSE
θ value	1.99992e-07 (rank : 94)	NC score	0.442639 (rank : 73)
Query Neighborhood Hits	613	Target Neighborhood Hits	505	Shared Neighborhood Hits	263
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

JAG2_HUMAN
θ value	1.99992e-07 (rank : 95)	NC score	0.467891 (rank : 46)
Query Neighborhood Hits	613	Target Neighborhood Hits	491	Shared Neighborhood Hits	302
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

KRA58_HUMAN
θ value	2.61198e-07 (rank : 96)	NC score	0.474179 (rank : 40)
Query Neighborhood Hits	613	Target Neighborhood Hits	324	Shared Neighborhood Hits	229
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LDLR_MOUSE
θ value	2.61198e-07 (rank : 97)	NC score	0.345989 (rank : 166)
Query Neighborhood Hits	613	Target Neighborhood Hits	382	Shared Neighborhood Hits	256
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

FBLN5_HUMAN
θ value	3.41135e-07 (rank : 98)	NC score	0.409023 (rank : 112)
Query Neighborhood Hits	613	Target Neighborhood Hits	329	Shared Neighborhood Hits	247
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

KRA51_HUMAN
θ value	3.41135e-07 (rank : 99)	NC score	0.512057 (rank : 22)
Query Neighborhood Hits	613	Target Neighborhood Hits	288	Shared Neighborhood Hits	207
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

SCUB3_MOUSE
θ value	3.41135e-07 (rank : 100)	NC score	0.461335 (rank : 50)
Query Neighborhood Hits	613	Target Neighborhood Hits	442	Shared Neighborhood Hits	301
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

EGFR_MOUSE
θ value	4.45536e-07 (rank : 101)	NC score	0.098889 (rank : 501)
Query Neighborhood Hits	613	Target Neighborhood Hits	927	Shared Neighborhood Hits	112
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

INSR_MOUSE
θ value	4.45536e-07 (rank : 102)	NC score	0.095443 (rank : 512)
Query Neighborhood Hits	613	Target Neighborhood Hits	968	Shared Neighborhood Hits	122
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

LAMC1_HUMAN
θ value	4.45536e-07 (rank : 103)	NC score	0.388716 (rank : 131)
Query Neighborhood Hits	613	Target Neighborhood Hits	922	Shared Neighborhood Hits	304
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

FBLN1_MOUSE
θ value	5.81887e-07 (rank : 104)	NC score	0.433102 (rank : 88)
Query Neighborhood Hits	613	Target Neighborhood Hits	329	Shared Neighborhood Hits	251
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

LRP1B_MOUSE
θ value	5.81887e-07 (rank : 105)	NC score	0.388738 (rank : 130)
Query Neighborhood Hits	613	Target Neighborhood Hits	606	Shared Neighborhood Hits	338
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

ZNFX1_HUMAN
θ value	5.81887e-07 (rank : 106)	NC score	0.200218 (rank : 306)
Query Neighborhood Hits	613	Target Neighborhood Hits	308	Shared Neighborhood Hits	132
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

LRP1B_HUMAN
θ value	7.59969e-07 (rank : 107)	NC score	0.391518 (rank : 127)
Query Neighborhood Hits	613	Target Neighborhood Hits	602	Shared Neighborhood Hits	338
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LTBP3_HUMAN
θ value	7.59969e-07 (rank : 108)	NC score	0.451978 (rank : 60)
Query Neighborhood Hits	613	Target Neighborhood Hits	502	Shared Neighborhood Hits	300
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LAMC2_MOUSE
θ value	9.92553e-07 (rank : 109)	NC score	0.405718 (rank : 115)
Query Neighborhood Hits	613	Target Neighborhood Hits	614	Shared Neighborhood Hits	303
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

HMCN1_HUMAN
θ value	1.29631e-06 (rank : 110)	NC score	0.268326 (rank : 260)
Query Neighborhood Hits	613	Target Neighborhood Hits	983	Shared Neighborhood Hits	284
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

JAG1_HUMAN
θ value	1.29631e-06 (rank : 111)	NC score	0.474256 (rank : 39)
Query Neighborhood Hits	613	Target Neighborhood Hits	514	Shared Neighborhood Hits	314
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

LAMA4_HUMAN
θ value	1.29631e-06 (rank : 112)	NC score	0.323681 (rank : 192)
Query Neighborhood Hits	613	Target Neighborhood Hits	708	Shared Neighborhood Hits	201
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

KRA59_HUMAN
θ value	1.69304e-06 (rank : 113)	NC score	0.484602 (rank : 34)
Query Neighborhood Hits	613	Target Neighborhood Hits	310	Shared Neighborhood Hits	213
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

TIE1_MOUSE
θ value	1.69304e-06 (rank : 114)	NC score	0.163636 (rank : 350)
Query Neighborhood Hits	613	Target Neighborhood Hits	1266	Shared Neighborhood Hits	252
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

INSRR_HUMAN
θ value	2.21117e-06 (rank : 115)	NC score	0.106949 (rank : 473)
Query Neighborhood Hits	613	Target Neighborhood Hits	950	Shared Neighborhood Hits	133
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

LAMA4_MOUSE
θ value	2.21117e-06 (rank : 116)	NC score	0.343470 (rank : 169)
Query Neighborhood Hits	613	Target Neighborhood Hits	584	Shared Neighborhood Hits	207
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

INSRR_MOUSE
θ value	2.88788e-06 (rank : 117)	NC score	0.107542 (rank : 471)
Query Neighborhood Hits	613	Target Neighborhood Hits	961	Shared Neighborhood Hits	147
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

KR107_HUMAN
θ value	2.88788e-06 (rank : 118)	NC score	0.442440 (rank : 75)
Query Neighborhood Hits	613	Target Neighborhood Hits	330	Shared Neighborhood Hits	238
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

LTB1L_MOUSE
θ value	2.88788e-06 (rank : 119)	NC score	0.450567 (rank : 64)
Query Neighborhood Hits	613	Target Neighborhood Hits	514	Shared Neighborhood Hits	299
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	2.88788e-06 (rank : 120)	NC score	0.451239 (rank : 61)
Query Neighborhood Hits	613	Target Neighborhood Hits	479	Shared Neighborhood Hits	284
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

INSR_HUMAN
θ value	3.77169e-06 (rank : 121)	NC score	0.096566 (rank : 508)
Query Neighborhood Hits	613	Target Neighborhood Hits	963	Shared Neighborhood Hits	129
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

PGBM_HUMAN
θ value	3.77169e-06 (rank : 122)	NC score	0.290158 (rank : 237)
Query Neighborhood Hits	613	Target Neighborhood Hits	1113	Shared Neighborhood Hits	323
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

STAB1_MOUSE
θ value	3.77169e-06 (rank : 123)	NC score	0.453182 (rank : 58)
Query Neighborhood Hits	613	Target Neighborhood Hits	566	Shared Neighborhood Hits	341
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TIE1_HUMAN
θ value	3.77169e-06 (rank : 124)	NC score	0.168821 (rank : 341)
Query Neighborhood Hits	613	Target Neighborhood Hits	1241	Shared Neighborhood Hits	250
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

VWF_HUMAN
θ value	3.77169e-06 (rank : 125)	NC score	0.302913 (rank : 220)
Query Neighborhood Hits	613	Target Neighborhood Hits	396	Shared Neighborhood Hits	242
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

LAMC1_MOUSE
θ value	6.43352e-06 (rank : 126)	NC score	0.397213 (rank : 123)
Query Neighborhood Hits	613	Target Neighborhood Hits	856	Shared Neighborhood Hits	301
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LDLR_HUMAN
θ value	6.43352e-06 (rank : 127)	NC score	0.354900 (rank : 159)
Query Neighborhood Hits	613	Target Neighborhood Hits	375	Shared Neighborhood Hits	260
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

KR106_HUMAN
θ value	1.09739e-05 (rank : 128)	NC score	0.442464 (rank : 74)
Query Neighborhood Hits	613	Target Neighborhood Hits	347	Shared Neighborhood Hits	257
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KRA55_HUMAN
θ value	1.43324e-05 (rank : 129)	NC score	0.471409 (rank : 43)
Query Neighborhood Hits	613	Target Neighborhood Hits	257	Shared Neighborhood Hits	182
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LAMA3_MOUSE
θ value	1.43324e-05 (rank : 130)	NC score	0.383316 (rank : 135)
Query Neighborhood Hits	613	Target Neighborhood Hits	859	Shared Neighborhood Hits	322
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMB3_HUMAN
θ value	1.43324e-05 (rank : 131)	NC score	0.384006 (rank : 134)
Query Neighborhood Hits	613	Target Neighborhood Hits	461	Shared Neighborhood Hits	203
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

ITB1_MOUSE
θ value	1.87187e-05 (rank : 132)	NC score	0.309646 (rank : 213)
Query Neighborhood Hits	613	Target Neighborhood Hits	283	Shared Neighborhood Hits	224
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB5_HUMAN
θ value	1.87187e-05 (rank : 133)	NC score	0.337258 (rank : 178)
Query Neighborhood Hits	613	Target Neighborhood Hits	310	Shared Neighborhood Hits	247
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

KRA53_HUMAN
θ value	1.87187e-05 (rank : 134)	NC score	0.508859 (rank : 23)
Query Neighborhood Hits	613	Target Neighborhood Hits	331	Shared Neighborhood Hits	246
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

LRP4_HUMAN
θ value	1.87187e-05 (rank : 135)	NC score	0.315795 (rank : 203)
Query Neighborhood Hits	613	Target Neighborhood Hits	355	Shared Neighborhood Hits	232
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

MATN4_MOUSE
θ value	1.87187e-05 (rank : 136)	NC score	0.320347 (rank : 199)
Query Neighborhood Hits	613	Target Neighborhood Hits	277	Shared Neighborhood Hits	183
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

PGBM_MOUSE
θ value	1.87187e-05 (rank : 137)	NC score	0.301058 (rank : 225)
Query Neighborhood Hits	613	Target Neighborhood Hits	1073	Shared Neighborhood Hits	336
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

JAG1_MOUSE
θ value	2.44474e-05 (rank : 138)	NC score	0.472033 (rank : 42)
Query Neighborhood Hits	613	Target Neighborhood Hits	518	Shared Neighborhood Hits	316
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

KRA45_HUMAN
θ value	2.44474e-05 (rank : 139)	NC score	0.323108 (rank : 195)
Query Neighborhood Hits	613	Target Neighborhood Hits	194	Shared Neighborhood Hits	148
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

ITB5_MOUSE
θ value	4.1701e-05 (rank : 140)	NC score	0.347702 (rank : 164)
Query Neighborhood Hits	613	Target Neighborhood Hits	329	Shared Neighborhood Hits	267
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

MATN3_HUMAN
θ value	4.1701e-05 (rank : 141)	NC score	0.330952 (rank : 184)
Query Neighborhood Hits	613	Target Neighborhood Hits	268	Shared Neighborhood Hits	177
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

TNR25_HUMAN
θ value	4.1701e-05 (rank : 142)	NC score	0.253054 (rank : 271)
Query Neighborhood Hits	613	Target Neighborhood Hits	172	Shared Neighborhood Hits	121
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

VWF_MOUSE
θ value	4.1701e-05 (rank : 143)	NC score	0.291728 (rank : 235)
Query Neighborhood Hits	613	Target Neighborhood Hits	381	Shared Neighborhood Hits	238
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CUBN_HUMAN
θ value	5.44631e-05 (rank : 144)	NC score	0.372166 (rank : 142)
Query Neighborhood Hits	613	Target Neighborhood Hits	482	Shared Neighborhood Hits	277
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

DLL4_MOUSE
θ value	5.44631e-05 (rank : 145)	NC score	0.446295 (rank : 67)
Query Neighborhood Hits	613	Target Neighborhood Hits	440	Shared Neighborhood Hits	294
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

TECTA_MOUSE
θ value	5.44631e-05 (rank : 146)	NC score	0.226567 (rank : 287)
Query Neighborhood Hits	613	Target Neighborhood Hits	244	Shared Neighborhood Hits	187
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TIE2_MOUSE
θ value	5.44631e-05 (rank : 147)	NC score	0.154744 (rank : 365)
Query Neighborhood Hits	613	Target Neighborhood Hits	1204	Shared Neighborhood Hits	247
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

NSD1_MOUSE
θ value	7.1131e-05 (rank : 148)	NC score	0.056552 (rank : 659)
Query Neighborhood Hits	613	Target Neighborhood Hits	472	Shared Neighborhood Hits	33
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

C1QR1_HUMAN
θ value	9.29e-05 (rank : 149)	NC score	0.404570 (rank : 117)
Query Neighborhood Hits	613	Target Neighborhood Hits	493	Shared Neighborhood Hits	252
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

ITB2_MOUSE
θ value	9.29e-05 (rank : 150)	NC score	0.334906 (rank : 182)
Query Neighborhood Hits	613	Target Neighborhood Hits	326	Shared Neighborhood Hits	263
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_MOUSE
θ value	9.29e-05 (rank : 151)	NC score	0.328257 (rank : 187)
Query Neighborhood Hits	613	Target Neighborhood Hits	319	Shared Neighborhood Hits	253
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB8_HUMAN
θ value	9.29e-05 (rank : 152)	NC score	0.284215 (rank : 243)
Query Neighborhood Hits	613	Target Neighborhood Hits	280	Shared Neighborhood Hits	222
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KR104_HUMAN
θ value	9.29e-05 (rank : 153)	NC score	0.437359 (rank : 83)
Query Neighborhood Hits	613	Target Neighborhood Hits	313	Shared Neighborhood Hits	222
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

NELL1_HUMAN
θ value	9.29e-05 (rank : 154)	NC score	0.476746 (rank : 38)
Query Neighborhood Hits	613	Target Neighborhood Hits	451	Shared Neighborhood Hits	307
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

CRUM1_HUMAN
θ value	0.000121331 (rank : 155)	NC score	0.432547 (rank : 89)
Query Neighborhood Hits	613	Target Neighborhood Hits	457	Shared Neighborhood Hits	284
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

MATN4_HUMAN
θ value	0.000121331 (rank : 156)	NC score	0.321958 (rank : 197)
Query Neighborhood Hits	613	Target Neighborhood Hits	287	Shared Neighborhood Hits	194
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

STAB2_HUMAN
θ value	0.000121331 (rank : 157)	NC score	0.450927 (rank : 63)
Query Neighborhood Hits	613	Target Neighborhood Hits	534	Shared Neighborhood Hits	336
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

UROM_MOUSE
θ value	0.000158464 (rank : 158)	NC score	0.369128 (rank : 147)
Query Neighborhood Hits	613	Target Neighborhood Hits	276	Shared Neighborhood Hits	212
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ATRN_MOUSE
θ value	0.00020696 (rank : 159)	NC score	0.318512 (rank : 201)
Query Neighborhood Hits	613	Target Neighborhood Hits	519	Shared Neighborhood Hits	246
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

LYAM2_HUMAN
θ value	0.00020696 (rank : 160)	NC score	0.209377 (rank : 298)
Query Neighborhood Hits	613	Target Neighborhood Hits	394	Shared Neighborhood Hits	208
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

TNR16_HUMAN
θ value	0.00020696 (rank : 161)	NC score	0.262865 (rank : 266)
Query Neighborhood Hits	613	Target Neighborhood Hits	183	Shared Neighborhood Hits	142
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	0.00020696 (rank : 162)	NC score	0.254332 (rank : 270)
Query Neighborhood Hits	613	Target Neighborhood Hits	178	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

ZN441_HUMAN
θ value	0.00020696 (rank : 163)	NC score	0.026605 (rank : 731)
Query Neighborhood Hits	613	Target Neighborhood Hits	754	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N8Z8	Gene names	ZNF441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 441.

DLL1_MOUSE
θ value	0.000270298 (rank : 164)	NC score	0.446263 (rank : 68)
Query Neighborhood Hits	613	Target Neighborhood Hits	456	Shared Neighborhood Hits	306
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

ITB3_HUMAN
θ value	0.000270298 (rank : 165)	NC score	0.340281 (rank : 173)
Query Neighborhood Hits	613	Target Neighborhood Hits	325	Shared Neighborhood Hits	266
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

SORL_HUMAN
θ value	0.000270298 (rank : 166)	NC score	0.274258 (rank : 255)
Query Neighborhood Hits	613	Target Neighborhood Hits	440	Shared Neighborhood Hits	224
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

STAB1_HUMAN
θ value	0.000270298 (rank : 167)	NC score	0.453783 (rank : 57)
Query Neighborhood Hits	613	Target Neighborhood Hits	546	Shared Neighborhood Hits	334
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB2_MOUSE
θ value	0.000270298 (rank : 168)	NC score	0.451059 (rank : 62)
Query Neighborhood Hits	613	Target Neighborhood Hits	528	Shared Neighborhood Hits	337
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TECTA_HUMAN
θ value	0.000270298 (rank : 169)	NC score	0.211778 (rank : 297)
Query Neighborhood Hits	613	Target Neighborhood Hits	239	Shared Neighborhood Hits	176
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

ZN611_HUMAN
θ value	0.000270298 (rank : 170)	NC score	0.025450 (rank : 734)
Query Neighborhood Hits	613	Target Neighborhood Hits	769	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N823, Q69YG9	Gene names	ZNF611
Domain Architecture	No domain graphic available
Description	Zinc finger protein 611.

ZNFX1_MOUSE
θ value	0.000270298 (rank : 171)	NC score	0.190925 (rank : 314)
Query Neighborhood Hits	613	Target Neighborhood Hits	407	Shared Neighborhood Hits	140
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

AGRIN_HUMAN
θ value	0.00035302 (rank : 172)	NC score	0.416422 (rank : 100)
Query Neighborhood Hits	613	Target Neighborhood Hits	582	Shared Neighborhood Hits	298
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

DNER_HUMAN
θ value	0.00035302 (rank : 173)	NC score	0.435265 (rank : 86)
Query Neighborhood Hits	613	Target Neighborhood Hits	460	Shared Neighborhood Hits	276
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

FBLN4_MOUSE
θ value	0.00035302 (rank : 174)	NC score	0.394571 (rank : 126)
Query Neighborhood Hits	613	Target Neighborhood Hits	270	Shared Neighborhood Hits	206
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

KR510_HUMAN
θ value	0.00035302 (rank : 175)	NC score	0.411056 (rank : 108)
Query Neighborhood Hits	613	Target Neighborhood Hits	217	Shared Neighborhood Hits	153
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

LYAM2_MOUSE
θ value	0.00035302 (rank : 176)	NC score	0.215185 (rank : 294)
Query Neighborhood Hits	613	Target Neighborhood Hits	420	Shared Neighborhood Hits	229
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

ZN286_HUMAN
θ value	0.00035302 (rank : 177)	NC score	0.023016 (rank : 755)
Query Neighborhood Hits	613	Target Neighborhood Hits	775	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HBT8, Q96JF3	Gene names	ZNF286, KIAA1874
Domain Architecture
Description	Zinc finger protein 286.

SORL_MOUSE
θ value	0.000461057 (rank : 178)	NC score	0.282000 (rank : 246)
Query Neighborhood Hits	613	Target Neighborhood Hits	439	Shared Neighborhood Hits	231
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TRBM_MOUSE
θ value	0.000461057 (rank : 179)	NC score	0.415802 (rank : 101)
Query Neighborhood Hits	613	Target Neighborhood Hits	361	Shared Neighborhood Hits	246
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

CRUM1_MOUSE
θ value	0.000602161 (rank : 180)	NC score	0.432274 (rank : 90)
Query Neighborhood Hits	613	Target Neighborhood Hits	444	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CUBN_MOUSE
θ value	0.000602161 (rank : 181)	NC score	0.370156 (rank : 143)
Query Neighborhood Hits	613	Target Neighborhood Hits	477	Shared Neighborhood Hits	273
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

LAMA3_HUMAN
θ value	0.000602161 (rank : 182)	NC score	0.336738 (rank : 180)
Query Neighborhood Hits	613	Target Neighborhood Hits	760	Shared Neighborhood Hits	245
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

TSP1_HUMAN
θ value	0.000602161 (rank : 183)	NC score	0.281521 (rank : 247)
Query Neighborhood Hits	613	Target Neighborhood Hits	389	Shared Neighborhood Hits	246
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

ATS9_HUMAN
θ value	0.000786445 (rank : 184)	NC score	0.074826 (rank : 572)
Query Neighborhood Hits	613	Target Neighborhood Hits	219	Shared Neighborhood Hits	113
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

KR108_HUMAN
θ value	0.000786445 (rank : 185)	NC score	0.336990 (rank : 179)
Query Neighborhood Hits	613	Target Neighborhood Hits	226	Shared Neighborhood Hits	163
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

NFX1_HUMAN
θ value	0.000786445 (rank : 186)	NC score	0.315834 (rank : 202)
Query Neighborhood Hits	613	Target Neighborhood Hits	405	Shared Neighborhood Hits	209
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

TNR1A_HUMAN
θ value	0.000786445 (rank : 187)	NC score	0.165577 (rank : 348)
Query Neighborhood Hits	613	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

ADA19_MOUSE
θ value	0.00102713 (rank : 188)	NC score	0.128852 (rank : 420)
Query Neighborhood Hits	613	Target Neighborhood Hits	315	Shared Neighborhood Hits	184
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

GRN_HUMAN
θ value	0.00102713 (rank : 189)	NC score	0.373714 (rank : 140)
Query Neighborhood Hits	613	Target Neighborhood Hits	268	Shared Neighborhood Hits	204
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KRA52_HUMAN
θ value	0.00102713 (rank : 190)	NC score	0.429840 (rank : 92)
Query Neighborhood Hits	613	Target Neighborhood Hits	236	Shared Neighborhood Hits	170
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LRP8_MOUSE
θ value	0.00102713 (rank : 191)	NC score	0.338237 (rank : 176)
Query Neighborhood Hits	613	Target Neighborhood Hits	385	Shared Neighborhood Hits	246
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

NID2_HUMAN
θ value	0.00102713 (rank : 192)	NC score	0.380338 (rank : 137)
Query Neighborhood Hits	613	Target Neighborhood Hits	456	Shared Neighborhood Hits	241
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

DNER_MOUSE
θ value	0.00134147 (rank : 193)	NC score	0.427111 (rank : 95)
Query Neighborhood Hits	613	Target Neighborhood Hits	413	Shared Neighborhood Hits	268
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

ITB2_HUMAN
θ value	0.00134147 (rank : 194)	NC score	0.313314 (rank : 208)
Query Neighborhood Hits	613	Target Neighborhood Hits	282	Shared Neighborhood Hits	236
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB7_HUMAN
θ value	0.00134147 (rank : 195)	NC score	0.330007 (rank : 185)
Query Neighborhood Hits	613	Target Neighborhood Hits	290	Shared Neighborhood Hits	234
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

TNR23_MOUSE
θ value	0.00134147 (rank : 196)	NC score	0.207410 (rank : 299)
Query Neighborhood Hits	613	Target Neighborhood Hits	114	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TR11B_HUMAN
θ value	0.00134147 (rank : 197)	NC score	0.140978 (rank : 392)
Query Neighborhood Hits	613	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

CORIN_MOUSE
θ value	0.00175202 (rank : 198)	NC score	0.116063 (rank : 453)
Query Neighborhood Hits	613	Target Neighborhood Hits	451	Shared Neighborhood Hits	185
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

DLL1_HUMAN
θ value	0.00175202 (rank : 199)	NC score	0.439617 (rank : 81)
Query Neighborhood Hits	613	Target Neighborhood Hits	455	Shared Neighborhood Hits	303
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

ITB7_MOUSE
θ value	0.00175202 (rank : 200)	NC score	0.326051 (rank : 189)
Query Neighborhood Hits	613	Target Neighborhood Hits	277	Shared Neighborhood Hits	219
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

LAMC2_HUMAN
θ value	0.00175202 (rank : 201)	NC score	0.384119 (rank : 133)
Query Neighborhood Hits	613	Target Neighborhood Hits	715	Shared Neighborhood Hits	290
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LRP4_MOUSE
θ value	0.00175202 (rank : 202)	NC score	0.315051 (rank : 205)
Query Neighborhood Hits	613	Target Neighborhood Hits	351	Shared Neighborhood Hits	226
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

MLL3_HUMAN
θ value	0.00175202 (rank : 203)	NC score	0.059253 (rank : 644)
Query Neighborhood Hits	613	Target Neighborhood Hits	1644	Shared Neighborhood Hits	115
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

DLL4_HUMAN
θ value	0.00228821 (rank : 204)	NC score	0.439908 (rank : 80)
Query Neighborhood Hits	613	Target Neighborhood Hits	435	Shared Neighborhood Hits	286
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

FBLN4_HUMAN
θ value	0.00228821 (rank : 205)	NC score	0.396042 (rank : 125)
Query Neighborhood Hits	613	Target Neighborhood Hits	278	Shared Neighborhood Hits	210
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

MATN3_MOUSE
θ value	0.00228821 (rank : 206)	NC score	0.322810 (rank : 196)
Query Neighborhood Hits	613	Target Neighborhood Hits	261	Shared Neighborhood Hits	180
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

NSD1_HUMAN
θ value	0.00228821 (rank : 207)	NC score	0.050472 (rank : 693)
Query Neighborhood Hits	613	Target Neighborhood Hits	427	Shared Neighborhood Hits	28
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

TNR7_HUMAN
θ value	0.00228821 (rank : 208)	NC score	0.189631 (rank : 315)
Query Neighborhood Hits	613	Target Neighborhood Hits	120	Shared Neighborhood Hits	106
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

C1QR1_MOUSE
θ value	0.00298849 (rank : 209)	NC score	0.390673 (rank : 128)
Query Neighborhood Hits	613	Target Neighborhood Hits	342	Shared Neighborhood Hits	230
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

FHL3_MOUSE
θ value	0.00298849 (rank : 210)	NC score	0.075378 (rank : 568)
Query Neighborhood Hits	613	Target Neighborhood Hits	424	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R059, Q9JLP5, Q9WUH3	Gene names	Fhl3
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

ITB6_MOUSE
θ value	0.00298849 (rank : 211)	NC score	0.338829 (rank : 175)
Query Neighborhood Hits	613	Target Neighborhood Hits	341	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

KR105_HUMAN
θ value	0.00298849 (rank : 212)	NC score	0.354656 (rank : 160)
Query Neighborhood Hits	613	Target Neighborhood Hits	271	Shared Neighborhood Hits	198
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

NTNG2_HUMAN
θ value	0.00298849 (rank : 213)	NC score	0.351126 (rank : 162)
Query Neighborhood Hits	613	Target Neighborhood Hits	276	Shared Neighborhood Hits	197
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

TRBM_HUMAN
θ value	0.00298849 (rank : 214)	NC score	0.414143 (rank : 103)
Query Neighborhood Hits	613	Target Neighborhood Hits	339	Shared Neighborhood Hits	236
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ZN613_HUMAN
θ value	0.00298849 (rank : 215)	NC score	0.023755 (rank : 749)
Query Neighborhood Hits	613	Target Neighborhood Hits	746	Shared Neighborhood Hits	80
SwissProt Accessions	Q6PF04, Q96SS9	Gene names	ZNF613
Domain Architecture	No domain graphic available
Description	Zinc finger protein 613.

FHL2_HUMAN
θ value	0.00390308 (rank : 216)	NC score	0.058835 (rank : 648)
Query Neighborhood Hits	613	Target Neighborhood Hits	533	Shared Neighborhood Hits	103
SwissProt Accessions	Q14192, Q13229, Q13644, Q9P294	Gene names	FHL2, DRAL, SLIM3
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3) (LIM-domain protein DRAL).

MUC5B_HUMAN
θ value	0.00390308 (rank : 217)	NC score	0.274716 (rank : 253)
Query Neighborhood Hits	613	Target Neighborhood Hits	1020	Shared Neighborhood Hits	272
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

ZN709_HUMAN
θ value	0.00390308 (rank : 218)	NC score	0.024633 (rank : 738)
Query Neighborhood Hits	613	Target Neighborhood Hits	746	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N972	Gene names	ZNF709
Domain Architecture	No domain graphic available
Description	Zinc finger protein 709.

EPHB2_HUMAN
θ value	0.00509761 (rank : 219)	NC score	0.055429 (rank : 665)
Query Neighborhood Hits	613	Target Neighborhood Hits	983	Shared Neighborhood Hits	89
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	0.00509761 (rank : 220)	NC score	0.055434 (rank : 664)
Query Neighborhood Hits	613	Target Neighborhood Hits	982	Shared Neighborhood Hits	89
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

TR10D_HUMAN
θ value	0.00509761 (rank : 221)	NC score	0.110908 (rank : 466)
Query Neighborhood Hits	613	Target Neighborhood Hits	62	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

ZNF28_HUMAN
θ value	0.00509761 (rank : 222)	NC score	0.023357 (rank : 754)
Query Neighborhood Hits	613	Target Neighborhood Hits	760	Shared Neighborhood Hits	81
SwissProt Accessions	P17035, Q5HYM9, Q6ZML9, Q6ZN56	Gene names	ZNF28, KOX24
Domain Architecture	No domain graphic available
Description	Zinc finger protein 28 (Zinc finger protein KOX24).

ZNF77_HUMAN
θ value	0.00509761 (rank : 223)	NC score	0.025448 (rank : 735)
Query Neighborhood Hits	613	Target Neighborhood Hits	759	Shared Neighborhood Hits	84
SwissProt Accessions	Q15935, Q86XJ3, Q9NPP0	Gene names	ZNF77
Domain Architecture	No domain graphic available
Description	Zinc finger protein 77 (ZNFpT1).

CORIN_HUMAN
θ value	0.00665767 (rank : 224)	NC score	0.128088 (rank : 423)
Query Neighborhood Hits	613	Target Neighborhood Hits	453	Shared Neighborhood Hits	189
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

MLL3_MOUSE
θ value	0.00665767 (rank : 225)	NC score	0.067192 (rank : 601)
Query Neighborhood Hits	613	Target Neighborhood Hits	1399	Shared Neighborhood Hits	111
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NID1_MOUSE
θ value	0.00665767 (rank : 226)	NC score	0.363236 (rank : 155)
Query Neighborhood Hits	613	Target Neighborhood Hits	335	Shared Neighborhood Hits	227
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

PRDM1_MOUSE
θ value	0.00665767 (rank : 227)	NC score	0.021071 (rank : 785)
Query Neighborhood Hits	613	Target Neighborhood Hits	766	Shared Neighborhood Hits	67
SwissProt Accessions	Q60636	Gene names	Prdm1, Blimp1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1).

PROS_HUMAN
θ value	0.00665767 (rank : 228)	NC score	0.367403 (rank : 148)
Query Neighborhood Hits	613	Target Neighborhood Hits	340	Shared Neighborhood Hits	239
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

TNR22_MOUSE
θ value	0.00665767 (rank : 229)	NC score	0.178621 (rank : 325)
Query Neighborhood Hits	613	Target Neighborhood Hits	97	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

WIF1_MOUSE
θ value	0.00665767 (rank : 230)	NC score	0.430220 (rank : 91)
Query Neighborhood Hits	613	Target Neighborhood Hits	393	Shared Neighborhood Hits	284
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

GRN_MOUSE
θ value	0.00869519 (rank : 231)	NC score	0.369197 (rank : 146)
Query Neighborhood Hits	613	Target Neighborhood Hits	248	Shared Neighborhood Hits	197
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

LRP8_HUMAN
θ value	0.00869519 (rank : 232)	NC score	0.320552 (rank : 198)
Query Neighborhood Hits	613	Target Neighborhood Hits	346	Shared Neighborhood Hits	223
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MUC2_HUMAN
θ value	0.00869519 (rank : 233)	NC score	0.189525 (rank : 316)
Query Neighborhood Hits	613	Target Neighborhood Hits	906	Shared Neighborhood Hits	183
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

TSP1_MOUSE
θ value	0.00869519 (rank : 234)	NC score	0.280236 (rank : 248)
Query Neighborhood Hits	613	Target Neighborhood Hits	396	Shared Neighborhood Hits	247
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

CELR2_HUMAN
θ value	0.0113563 (rank : 235)	NC score	0.194042 (rank : 312)
Query Neighborhood Hits	613	Target Neighborhood Hits	657	Shared Neighborhood Hits	273
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

EGFL9_MOUSE
θ value	0.0113563 (rank : 236)	NC score	0.413178 (rank : 105)
Query Neighborhood Hits	613	Target Neighborhood Hits	379	Shared Neighborhood Hits	264
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

PROS_MOUSE
θ value	0.0113563 (rank : 237)	NC score	0.366977 (rank : 149)
Query Neighborhood Hits	613	Target Neighborhood Hits	330	Shared Neighborhood Hits	233
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

TIE2_HUMAN
θ value	0.0113563 (rank : 238)	NC score	0.146724 (rank : 376)
Query Neighborhood Hits	613	Target Neighborhood Hits	1192	Shared Neighborhood Hits	237
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TNR1B_MOUSE
θ value	0.0113563 (rank : 239)	NC score	0.153583 (rank : 367)
Query Neighborhood Hits	613	Target Neighborhood Hits	123	Shared Neighborhood Hits	82
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR9_MOUSE
θ value	0.0113563 (rank : 240)	NC score	0.200539 (rank : 305)
Query Neighborhood Hits	613	Target Neighborhood Hits	137	Shared Neighborhood Hits	116
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

BAI2_HUMAN
θ value	0.0148317 (rank : 241)	NC score	0.067508 (rank : 600)
Query Neighborhood Hits	613	Target Neighborhood Hits	332	Shared Neighborhood Hits	62
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	0.0148317 (rank : 242)	NC score	0.067962 (rank : 598)
Query Neighborhood Hits	613	Target Neighborhood Hits	323	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

EGFL9_HUMAN
θ value	0.0148317 (rank : 243)	NC score	0.415766 (rank : 102)
Query Neighborhood Hits	613	Target Neighborhood Hits	365	Shared Neighborhood Hits	261
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGF_HUMAN
θ value	0.0148317 (rank : 244)	NC score	0.358695 (rank : 158)
Query Neighborhood Hits	613	Target Neighborhood Hits	343	Shared Neighborhood Hits	231
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

FST_MOUSE
θ value	0.0148317 (rank : 245)	NC score	0.142561 (rank : 386)
Query Neighborhood Hits	613	Target Neighborhood Hits	146	Shared Neighborhood Hits	85
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

KR101_HUMAN
θ value	0.0148317 (rank : 246)	NC score	0.372550 (rank : 141)
Query Neighborhood Hits	613	Target Neighborhood Hits	261	Shared Neighborhood Hits	191
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KRA57_HUMAN
θ value	0.0148317 (rank : 247)	NC score	0.434351 (rank : 87)
Query Neighborhood Hits	613	Target Neighborhood Hits	269	Shared Neighborhood Hits	194
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

NET2_HUMAN
θ value	0.0148317 (rank : 248)	NC score	0.301332 (rank : 224)
Query Neighborhood Hits	613	Target Neighborhood Hits	194	Shared Neighborhood Hits	148
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

TNR1B_HUMAN
θ value	0.0148317 (rank : 249)	NC score	0.157803 (rank : 360)
Query Neighborhood Hits	613	Target Neighborhood Hits	127	Shared Neighborhood Hits	92
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR21_HUMAN
θ value	0.0148317 (rank : 250)	NC score	0.126813 (rank : 427)
Query Neighborhood Hits	613	Target Neighborhood Hits	90	Shared Neighborhood Hits	74
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

ADA22_HUMAN
θ value	0.0193708 (rank : 251)	NC score	0.108314 (rank : 468)
Query Neighborhood Hits	613	Target Neighborhood Hits	211	Shared Neighborhood Hits	145
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA29_HUMAN
θ value	0.0193708 (rank : 252)	NC score	0.086631 (rank : 538)
Query Neighborhood Hits	613	Target Neighborhood Hits	247	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

KR10B_HUMAN
θ value	0.0193708 (rank : 253)	NC score	0.349331 (rank : 163)
Query Neighborhood Hits	613	Target Neighborhood Hits	269	Shared Neighborhood Hits	189
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

TENN_MOUSE
θ value	0.0193708 (rank : 254)	NC score	0.225132 (rank : 289)
Query Neighborhood Hits	613	Target Neighborhood Hits	484	Shared Neighborhood Hits	252
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TNR9_HUMAN
θ value	0.0193708 (rank : 255)	NC score	0.197932 (rank : 308)
Query Neighborhood Hits	613	Target Neighborhood Hits	166	Shared Neighborhood Hits	136
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

UROM_HUMAN
θ value	0.0193708 (rank : 256)	NC score	0.370102 (rank : 144)
Query Neighborhood Hits	613	Target Neighborhood Hits	284	Shared Neighborhood Hits	211
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

WIF1_HUMAN
θ value	0.0193708 (rank : 257)	NC score	0.424427 (rank : 96)
Query Neighborhood Hits	613	Target Neighborhood Hits	392	Shared Neighborhood Hits	281
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ZN224_HUMAN
θ value	0.0193708 (rank : 258)	NC score	0.026723 (rank : 730)
Query Neighborhood Hits	613	Target Neighborhood Hits	808	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NZL3, Q86V10, Q8IZC8, Q9UID9, Q9Y2P6	Gene names	ZNF224, BMZF2, ZNF255
Domain Architecture
Description	Zinc finger protein 224 (Zinc finger protein 255) (Bone marrow zinc finger 2) (BMZF-2).

ZN334_HUMAN
θ value	0.0193708 (rank : 259)	NC score	0.023869 (rank : 747)
Query Neighborhood Hits	613	Target Neighborhood Hits	778	Shared Neighborhood Hits	84
SwissProt Accessions	Q9HCZ1, Q5T6U2, Q9NVW4	Gene names	ZNF334
Domain Architecture
Description	Zinc finger protein 334.

ZNF44_HUMAN
θ value	0.0193708 (rank : 260)	NC score	0.025293 (rank : 736)
Query Neighborhood Hits	613	Target Neighborhood Hits	757	Shared Neighborhood Hits	83
SwissProt Accessions	P15621, P17018, Q9ULZ7	Gene names	ZNF44, KOX7
Domain Architecture
Description	Zinc finger protein 44 (Zinc finger protein KOX7) (Gonadotropin- inducible transcription repressor 2) (GIOT-2).

CRUM2_HUMAN
θ value	0.0252991 (rank : 261)	NC score	0.428799 (rank : 93)
Query Neighborhood Hits	613	Target Neighborhood Hits	453	Shared Neighborhood Hits	289
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

EGF_MOUSE
θ value	0.0252991 (rank : 262)	NC score	0.369676 (rank : 145)
Query Neighborhood Hits	613	Target Neighborhood Hits	358	Shared Neighborhood Hits	242
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

FA76B_MOUSE
θ value	0.0252991 (rank : 263)	NC score	0.043552 (rank : 707)
Query Neighborhood Hits	613	Target Neighborhood Hits	181	Shared Neighborhood Hits	16
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

FHL1_HUMAN
θ value	0.0252991 (rank : 264)	NC score	0.051497 (rank : 685)
Query Neighborhood Hits	613	Target Neighborhood Hits	436	Shared Neighborhood Hits	76
SwissProt Accessions	Q13642, O95212, Q13230, Q13645, Q5M7Y6, Q9NZ40, Q9UKZ8, Q9Y630	Gene names	FHL1, SLIM1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM).

MT1L_HUMAN
θ value	0.0252991 (rank : 265)	NC score	0.160479 (rank : 356)
Query Neighborhood Hits	613	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT3_HUMAN
θ value	0.0252991 (rank : 266)	NC score	0.225354 (rank : 288)
Query Neighborhood Hits	613	Target Neighborhood Hits	82	Shared Neighborhood Hits	69
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

PRDM1_HUMAN
θ value	0.0252991 (rank : 267)	NC score	0.020705 (rank : 791)
Query Neighborhood Hits	613	Target Neighborhood Hits	734	Shared Neighborhood Hits	67
SwissProt Accessions	O75626	Gene names	PRDM1, BLIMP1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1) (Positive regulatory domain I-binding factor 1) (PRDI- binding factor 1) (PRDI-BF1).

TNR3_HUMAN
θ value	0.0252991 (rank : 268)	NC score	0.157251 (rank : 361)
Query Neighborhood Hits	613	Target Neighborhood Hits	145	Shared Neighborhood Hits	87
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TR10B_HUMAN
θ value	0.0252991 (rank : 269)	NC score	0.116054 (rank : 454)
Query Neighborhood Hits	613	Target Neighborhood Hits	71	Shared Neighborhood Hits	60
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

ADA22_MOUSE
θ value	0.0330416 (rank : 270)	NC score	0.114061 (rank : 458)
Query Neighborhood Hits	613	Target Neighborhood Hits	225	Shared Neighborhood Hits	152
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ATRN_HUMAN
θ value	0.0330416 (rank : 271)	NC score	0.309001 (rank : 214)
Query Neighborhood Hits	613	Target Neighborhood Hits	525	Shared Neighborhood Hits	246
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

FST_HUMAN
θ value	0.0330416 (rank : 272)	NC score	0.127759 (rank : 424)
Query Neighborhood Hits	613	Target Neighborhood Hits	129	Shared Neighborhood Hits	68
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

MT1_MOUSE
θ value	0.0330416 (rank : 273)	NC score	0.167188 (rank : 346)
Query Neighborhood Hits	613	Target Neighborhood Hits	72	Shared Neighborhood Hits	58
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT4_HUMAN
θ value	0.0330416 (rank : 274)	NC score	0.195536 (rank : 311)
Query Neighborhood Hits	613	Target Neighborhood Hits	83	Shared Neighborhood Hits	69
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

TR11B_MOUSE
θ value	0.0330416 (rank : 275)	NC score	0.127509 (rank : 425)
Query Neighborhood Hits	613	Target Neighborhood Hits	95	Shared Neighborhood Hits	76
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

ZN350_HUMAN
θ value	0.0330416 (rank : 276)	NC score	0.021214 (rank : 781)
Query Neighborhood Hits	613	Target Neighborhood Hits	738	Shared Neighborhood Hits	74
SwissProt Accessions	Q9GZX5, Q9HAQ4	Gene names	ZNF350, ZBRK1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 350 (Zinc-finger protein ZBRK1) (Zinc finger and BRCA1-interacting protein with a KRAB domain 1) (KRAB zinc finger protein ZFQR).

ZN600_HUMAN
θ value	0.0330416 (rank : 277)	NC score	0.023433 (rank : 752)
Query Neighborhood Hits	613	Target Neighborhood Hits	774	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZNG1, Q6MZR0	Gene names	ZNF600
Domain Architecture	No domain graphic available
Description	Zinc finger protein 600.

ADA15_HUMAN
θ value	0.0431538 (rank : 278)	NC score	0.128673 (rank : 421)
Query Neighborhood Hits	613	Target Neighborhood Hits	288	Shared Neighborhood Hits	186
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ATS17_HUMAN
θ value	0.0431538 (rank : 279)	NC score	0.067166 (rank : 602)
Query Neighborhood Hits	613	Target Neighborhood Hits	194	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

EMR1_HUMAN
θ value	0.0431538 (rank : 280)	NC score	0.323330 (rank : 194)
Query Neighborhood Hits	613	Target Neighborhood Hits	382	Shared Neighborhood Hits	220
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

FHL5_HUMAN
θ value	0.0431538 (rank : 281)	NC score	0.060278 (rank : 638)
Query Neighborhood Hits	613	Target Neighborhood Hits	523	Shared Neighborhood Hits	96
SwissProt Accessions	Q5TD97, Q5TD98, Q8WW21, Q9NQU2	Gene names	FHL5, ACT
Domain Architecture	No domain graphic available
Description	Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP- responsive element modulator in testis) (Activator of CREM in testis).

ITB1_HUMAN
θ value	0.0431538 (rank : 282)	NC score	0.314379 (rank : 206)
Query Neighborhood Hits	613	Target Neighborhood Hits	298	Shared Neighborhood Hits	235
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KRA93_HUMAN
θ value	0.0431538 (rank : 283)	NC score	0.310695 (rank : 212)
Query Neighborhood Hits	613	Target Neighborhood Hits	203	Shared Neighborhood Hits	152
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

MT4_MOUSE
θ value	0.0431538 (rank : 284)	NC score	0.221285 (rank : 292)
Query Neighborhood Hits	613	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

TNR19_HUMAN
θ value	0.0431538 (rank : 285)	NC score	0.121970 (rank : 440)
Query Neighborhood Hits	613	Target Neighborhood Hits	89	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR4_MOUSE
θ value	0.0431538 (rank : 286)	NC score	0.199630 (rank : 307)
Query Neighborhood Hits	613	Target Neighborhood Hits	137	Shared Neighborhood Hits	115
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

DLL3_HUMAN
θ value	0.0563607 (rank : 287)	NC score	0.419481 (rank : 98)
Query Neighborhood Hits	613	Target Neighborhood Hits	419	Shared Neighborhood Hits	265
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

FBLN3_HUMAN
θ value	0.0563607 (rank : 288)	NC score	0.385477 (rank : 132)
Query Neighborhood Hits	613	Target Neighborhood Hits	293	Shared Neighborhood Hits	219
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FHL2_MOUSE
θ value	0.0563607 (rank : 289)	NC score	0.060231 (rank : 639)
Query Neighborhood Hits	613	Target Neighborhood Hits	539	Shared Neighborhood Hits	111
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

FHL5_MOUSE
θ value	0.0563607 (rank : 290)	NC score	0.057566 (rank : 655)
Query Neighborhood Hits	613	Target Neighborhood Hits	463	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WTX7	Gene names	Fhl5, Act
Domain Architecture	No domain graphic available
Description	Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP- responsive element modulator in testis) (Activator of CREM in testis).

KRA47_HUMAN
θ value	0.0563607 (rank : 291)	NC score	0.312306 (rank : 210)
Query Neighborhood Hits	613	Target Neighborhood Hits	204	Shared Neighborhood Hits	143
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA56_HUMAN
θ value	0.0563607 (rank : 292)	NC score	0.403356 (rank : 119)
Query Neighborhood Hits	613	Target Neighborhood Hits	207	Shared Neighborhood Hits	155
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

MT3_MOUSE
θ value	0.0563607 (rank : 293)	NC score	0.237646 (rank : 281)
Query Neighborhood Hits	613	Target Neighborhood Hits	68	Shared Neighborhood Hits	58
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

NET2_MOUSE
θ value	0.0563607 (rank : 294)	NC score	0.299009 (rank : 229)
Query Neighborhood Hits	613	Target Neighborhood Hits	193	Shared Neighborhood Hits	151
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

TNR7_MOUSE
θ value	0.0563607 (rank : 295)	NC score	0.150554 (rank : 370)
Query Neighborhood Hits	613	Target Neighborhood Hits	112	Shared Neighborhood Hits	88
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

VEGFC_HUMAN
θ value	0.0563607 (rank : 296)	NC score	0.137936 (rank : 399)
Query Neighborhood Hits	613	Target Neighborhood Hits	128	Shared Neighborhood Hits	98
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

FHL1_MOUSE
θ value	0.0736092 (rank : 297)	NC score	0.052834 (rank : 683)
Query Neighborhood Hits	613	Target Neighborhood Hits	462	Shared Neighborhood Hits	84
SwissProt Accessions	P97447, O55181, Q8K318	Gene names	Fhl1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM) (KyoT) (RBP-associated molecule 14-1) (RAM14-1).

FHL3_HUMAN
θ value	0.0736092 (rank : 298)	NC score	0.062795 (rank : 623)
Query Neighborhood Hits	613	Target Neighborhood Hits	354	Shared Neighborhood Hits	77
SwissProt Accessions	Q13643	Gene names	FHL3, SLIM2
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

PAP2_HUMAN
θ value	0.0736092 (rank : 299)	NC score	0.075479 (rank : 566)
Query Neighborhood Hits	613	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PAPPA_HUMAN
θ value	0.0736092 (rank : 300)	NC score	0.100352 (rank : 495)
Query Neighborhood Hits	613	Target Neighborhood Hits	161	Shared Neighborhood Hits	81
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

TNR1A_MOUSE
θ value	0.0736092 (rank : 301)	NC score	0.174865 (rank : 330)
Query Neighborhood Hits	613	Target Neighborhood Hits	131	Shared Neighborhood Hits	93
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TR10C_HUMAN
θ value	0.0736092 (rank : 302)	NC score	0.128573 (rank : 422)
Query Neighborhood Hits	613	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

EPHA1_HUMAN
θ value	0.0961366 (rank : 303)	NC score	0.063782 (rank : 620)
Query Neighborhood Hits	613	Target Neighborhood Hits	997	Shared Neighborhood Hits	121
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

KR10A_HUMAN
θ value	0.0961366 (rank : 304)	NC score	0.279667 (rank : 249)
Query Neighborhood Hits	613	Target Neighborhood Hits	232	Shared Neighborhood Hits	179
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

NID2_MOUSE
θ value	0.0961366 (rank : 305)	NC score	0.363665 (rank : 154)
Query Neighborhood Hits	613	Target Neighborhood Hits	338	Shared Neighborhood Hits	226
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

ADA18_HUMAN
θ value	0.125558 (rank : 306)	NC score	0.101953 (rank : 486)
Query Neighborhood Hits	613	Target Neighborhood Hits	184	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

EPHA2_HUMAN
θ value	0.125558 (rank : 307)	NC score	0.058646 (rank : 651)
Query Neighborhood Hits	613	Target Neighborhood Hits	1021	Shared Neighborhood Hits	100
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

FBLN3_MOUSE
θ value	0.125558 (rank : 308)	NC score	0.376114 (rank : 139)
Query Neighborhood Hits	613	Target Neighborhood Hits	279	Shared Neighborhood Hits	205
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBX5_HUMAN
θ value	0.125558 (rank : 309)	NC score	0.029883 (rank : 725)
Query Neighborhood Hits	613	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKT4, Q8WV29, Q9UGC8	Gene names	FBXO5, EMI1, FBX5
Domain Architecture	No domain graphic available
Description	F-box only protein 5 (Early mitotic inhibitor 1).

KR412_HUMAN
θ value	0.125558 (rank : 310)	NC score	0.286480 (rank : 241)
Query Neighborhood Hits	613	Target Neighborhood Hits	178	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

MT1E_HUMAN
θ value	0.125558 (rank : 311)	NC score	0.143032 (rank : 384)
Query Neighborhood Hits	613	Target Neighborhood Hits	75	Shared Neighborhood Hits	66
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT2_HUMAN
θ value	0.125558 (rank : 312)	NC score	0.138728 (rank : 398)
Query Neighborhood Hits	613	Target Neighborhood Hits	69	Shared Neighborhood Hits	63
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

MYST4_HUMAN
θ value	0.125558 (rank : 313)	NC score	0.026529 (rank : 732)
Query Neighborhood Hits	613	Target Neighborhood Hits	671	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	0.125558 (rank : 314)	NC score	0.029194 (rank : 727)
Query Neighborhood Hits	613	Target Neighborhood Hits	416	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

SRCH_HUMAN
θ value	0.125558 (rank : 315)	NC score	0.069746 (rank : 593)
Query Neighborhood Hits	613	Target Neighborhood Hits	225	Shared Neighborhood Hits	37
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TNR19_MOUSE
θ value	0.125558 (rank : 316)	NC score	0.128925 (rank : 419)
Query Neighborhood Hits	613	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR26_MOUSE
θ value	0.125558 (rank : 317)	NC score	0.185788 (rank : 321)
Query Neighborhood Hits	613	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TRAF2_HUMAN
θ value	0.125558 (rank : 318)	NC score	0.025777 (rank : 733)
Query Neighborhood Hits	613	Target Neighborhood Hits	402	Shared Neighborhood Hits	48
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

VEGFC_MOUSE
θ value	0.125558 (rank : 319)	NC score	0.116354 (rank : 452)
Query Neighborhood Hits	613	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

COMP_HUMAN
θ value	0.163984 (rank : 320)	NC score	0.311731 (rank : 211)
Query Neighborhood Hits	613	Target Neighborhood Hits	258	Shared Neighborhood Hits	206
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CSMD1_HUMAN
θ value	0.163984 (rank : 321)	NC score	0.054265 (rank : 673)
Query Neighborhood Hits	613	Target Neighborhood Hits	176	Shared Neighborhood Hits	57
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

DLL3_MOUSE
θ value	0.163984 (rank : 322)	NC score	0.410207 (rank : 111)
Query Neighborhood Hits	613	Target Neighborhood Hits	399	Shared Neighborhood Hits	256
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

KRA98_HUMAN
θ value	0.163984 (rank : 323)	NC score	0.301615 (rank : 222)
Query Neighborhood Hits	613	Target Neighborhood Hits	185	Shared Neighborhood Hits	142
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

MT1G_HUMAN
θ value	0.163984 (rank : 324)	NC score	0.144376 (rank : 383)
Query Neighborhood Hits	613	Target Neighborhood Hits	63	Shared Neighborhood Hits	54
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

MT2_MOUSE
θ value	0.163984 (rank : 325)	NC score	0.188037 (rank : 319)
Query Neighborhood Hits	613	Target Neighborhood Hits	81	Shared Neighborhood Hits	66
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

PROP_MOUSE
θ value	0.163984 (rank : 326)	NC score	0.094093 (rank : 517)
Query Neighborhood Hits	613	Target Neighborhood Hits	165	Shared Neighborhood Hits	65
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

SLIT1_HUMAN
θ value	0.163984 (rank : 327)	NC score	0.287923 (rank : 238)
Query Neighborhood Hits	613	Target Neighborhood Hits	700	Shared Neighborhood Hits	272
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

TENR_HUMAN
θ value	0.163984 (rank : 328)	NC score	0.265286 (rank : 265)
Query Neighborhood Hits	613	Target Neighborhood Hits	526	Shared Neighborhood Hits	265
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TNR21_MOUSE
θ value	0.163984 (rank : 329)	NC score	0.122298 (rank : 438)
Query Neighborhood Hits	613	Target Neighborhood Hits	108	Shared Neighborhood Hits	75
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR27_MOUSE
θ value	0.163984 (rank : 330)	NC score	0.081757 (rank : 551)
Query Neighborhood Hits	613	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TR13B_HUMAN
θ value	0.163984 (rank : 331)	NC score	0.059181 (rank : 646)
Query Neighborhood Hits	613	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	O14836, Q7Z6F5	Gene names	TNFRSF13B, TACI
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor) (CD267 antigen).

ADA11_MOUSE
θ value	0.21417 (rank : 332)	NC score	0.136163 (rank : 404)
Query Neighborhood Hits	613	Target Neighborhood Hits	263	Shared Neighborhood Hits	184
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA12_HUMAN
θ value	0.21417 (rank : 333)	NC score	0.107767 (rank : 470)
Query Neighborhood Hits	613	Target Neighborhood Hits	224	Shared Neighborhood Hits	140
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA20_HUMAN
θ value	0.21417 (rank : 334)	NC score	0.072076 (rank : 584)
Query Neighborhood Hits	613	Target Neighborhood Hits	143	Shared Neighborhood Hits	92
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ATS14_HUMAN
θ value	0.21417 (rank : 335)	NC score	0.049325 (rank : 699)
Query Neighborhood Hits	613	Target Neighborhood Hits	382	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

BMPER_MOUSE
θ value	0.21417 (rank : 336)	NC score	0.261261 (rank : 268)
Query Neighborhood Hits	613	Target Neighborhood Hits	194	Shared Neighborhood Hits	144
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

DLK_HUMAN
θ value	0.21417 (rank : 337)	NC score	0.424198 (rank : 97)
Query Neighborhood Hits	613	Target Neighborhood Hits	401	Shared Neighborhood Hits	279
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

KRA92_HUMAN
θ value	0.21417 (rank : 338)	NC score	0.298689 (rank : 230)
Query Neighborhood Hits	613	Target Neighborhood Hits	198	Shared Neighborhood Hits	152
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LRP3_HUMAN
θ value	0.21417 (rank : 339)	NC score	0.141002 (rank : 391)
Query Neighborhood Hits	613	Target Neighborhood Hits	280	Shared Neighborhood Hits	121
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

TR10B_MOUSE
θ value	0.21417 (rank : 340)	NC score	0.117621 (rank : 449)
Query Neighborhood Hits	613	Target Neighborhood Hits	76	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TRI42_HUMAN
θ value	0.21417 (rank : 341)	NC score	0.047665 (rank : 701)
Query Neighborhood Hits	613	Target Neighborhood Hits	283	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ZFP28_MOUSE
θ value	0.21417 (rank : 342)	NC score	0.024336 (rank : 742)
Query Neighborhood Hits	613	Target Neighborhood Hits	782	Shared Neighborhood Hits	83
SwissProt Accessions	P10078, Q61776, Q8BT11, Q8C836	Gene names	Zfp28, Mkr5, Zfp-28
Domain Architecture
Description	Zinc finger protein 28 (Zfp-28) (Protein mKR5).

ZN670_HUMAN
θ value	0.21417 (rank : 343)	NC score	0.021719 (rank : 773)
Query Neighborhood Hits	613	Target Neighborhood Hits	736	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BS34	Gene names	ZNF670
Domain Architecture	No domain graphic available
Description	Zinc finger protein 670.

ZNF7_HUMAN
θ value	0.21417 (rank : 344)	NC score	0.021893 (rank : 772)
Query Neighborhood Hits	613	Target Neighborhood Hits	770	Shared Neighborhood Hits	86
SwissProt Accessions	P17097, P17015	Gene names	ZNF7, KOX4
Domain Architecture
Description	Zinc finger protein 7 (Zinc finger protein KOX4) (Zinc finger protein HF.16).

ADA11_HUMAN
θ value	0.279714 (rank : 345)	NC score	0.135204 (rank : 406)
Query Neighborhood Hits	613	Target Neighborhood Hits	259	Shared Neighborhood Hits	184
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADAM2_MOUSE
θ value	0.279714 (rank : 346)	NC score	0.101945 (rank : 487)
Query Neighborhood Hits	613	Target Neighborhood Hits	209	Shared Neighborhood Hits	135
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

CSMD1_MOUSE
θ value	0.279714 (rank : 347)	NC score	0.058028 (rank : 654)
Query Neighborhood Hits	613	Target Neighborhood Hits	193	Shared Neighborhood Hits	68
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CT127_HUMAN
θ value	0.279714 (rank : 348)	NC score	0.161286 (rank : 355)
Query Neighborhood Hits	613	Target Neighborhood Hits	67	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

EPHA2_MOUSE
θ value	0.279714 (rank : 349)	NC score	0.063569 (rank : 621)
Query Neighborhood Hits	613	Target Neighborhood Hits	1020	Shared Neighborhood Hits	121
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

ITB4_HUMAN
θ value	0.279714 (rank : 350)	NC score	0.290198 (rank : 236)
Query Neighborhood Hits	613	Target Neighborhood Hits	458	Shared Neighborhood Hits	236
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KR109_HUMAN
θ value	0.279714 (rank : 351)	NC score	0.323582 (rank : 193)
Query Neighborhood Hits	613	Target Neighborhood Hits	226	Shared Neighborhood Hits	171
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR131_HUMAN
θ value	0.279714 (rank : 352)	NC score	0.089565 (rank : 529)
Query Neighborhood Hits	613	Target Neighborhood Hits	123	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

LYAM3_MOUSE
θ value	0.279714 (rank : 353)	NC score	0.228907 (rank : 285)
Query Neighborhood Hits	613	Target Neighborhood Hits	390	Shared Neighborhood Hits	207
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MLL2_HUMAN
θ value	0.279714 (rank : 354)	NC score	0.046463 (rank : 702)
Query Neighborhood Hits	613	Target Neighborhood Hits	1788	Shared Neighborhood Hits	91
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MT1A_HUMAN
θ value	0.279714 (rank : 355)	NC score	0.172076 (rank : 337)
Query Neighborhood Hits	613	Target Neighborhood Hits	74	Shared Neighborhood Hits	61
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1F_HUMAN
θ value	0.279714 (rank : 356)	NC score	0.140886 (rank : 393)
Query Neighborhood Hits	613	Target Neighborhood Hits	73	Shared Neighborhood Hits	64
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1X_HUMAN
θ value	0.279714 (rank : 357)	NC score	0.173146 (rank : 334)
Query Neighborhood Hits	613	Target Neighborhood Hits	76	Shared Neighborhood Hits	68
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MYCB2_HUMAN
θ value	0.279714 (rank : 358)	NC score	0.029961 (rank : 724)
Query Neighborhood Hits	613	Target Neighborhood Hits	390	Shared Neighborhood Hits	32
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NID1_HUMAN
θ value	0.279714 (rank : 359)	NC score	0.362152 (rank : 156)
Query Neighborhood Hits	613	Target Neighborhood Hits	329	Shared Neighborhood Hits	228
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

THYG_HUMAN
θ value	0.279714 (rank : 360)	NC score	0.054885 (rank : 671)
Query Neighborhood Hits	613	Target Neighborhood Hits	154	Shared Neighborhood Hits	70
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

TNR14_HUMAN
θ value	0.279714 (rank : 361)	NC score	0.212307 (rank : 296)
Query Neighborhood Hits	613	Target Neighborhood Hits	149	Shared Neighborhood Hits	127
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TSP2_MOUSE
θ value	0.279714 (rank : 362)	NC score	0.244846 (rank : 276)
Query Neighborhood Hits	613	Target Neighborhood Hits	352	Shared Neighborhood Hits	225
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ZN429_HUMAN
θ value	0.279714 (rank : 363)	NC score	0.022125 (rank : 763)
Query Neighborhood Hits	613	Target Neighborhood Hits	766	Shared Neighborhood Hits	82
SwissProt Accessions	Q86V71	Gene names	ZNF429
Domain Architecture
Description	Zinc finger protein 429.

ADM1B_MOUSE
θ value	0.365318 (rank : 364)	NC score	0.099143 (rank : 499)
Query Neighborhood Hits	613	Target Neighborhood Hits	236	Shared Neighborhood Hits	144
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

BMPER_HUMAN
θ value	0.365318 (rank : 365)	NC score	0.243714 (rank : 278)
Query Neighborhood Hits	613	Target Neighborhood Hits	175	Shared Neighborhood Hits	128
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

DLK_MOUSE
θ value	0.365318 (rank : 366)	NC score	0.418973 (rank : 99)
Query Neighborhood Hits	613	Target Neighborhood Hits	374	Shared Neighborhood Hits	258
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

EPHB3_MOUSE
θ value	0.365318 (rank : 367)	NC score	0.051230 (rank : 687)
Query Neighborhood Hits	613	Target Neighborhood Hits	996	Shared Neighborhood Hits	79
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

LRP10_HUMAN
θ value	0.365318 (rank : 368)	NC score	0.132608 (rank : 413)
Query Neighborhood Hits	613	Target Neighborhood Hits	197	Shared Neighborhood Hits	93
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	0.365318 (rank : 369)	NC score	0.134065 (rank : 409)
Query Neighborhood Hits	613	Target Neighborhood Hits	169	Shared Neighborhood Hits	90
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

MT1B_HUMAN
θ value	0.365318 (rank : 370)	NC score	0.158149 (rank : 359)
Query Neighborhood Hits	613	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MYST3_HUMAN
θ value	0.365318 (rank : 371)	NC score	0.022210 (rank : 762)
Query Neighborhood Hits	613	Target Neighborhood Hits	772	Shared Neighborhood Hits	26
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	0.365318 (rank : 372)	NC score	0.024122 (rank : 745)
Query Neighborhood Hits	613	Target Neighborhood Hits	688	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NTNG2_MOUSE
θ value	0.365318 (rank : 373)	NC score	0.346512 (rank : 165)
Query Neighborhood Hits	613	Target Neighborhood Hits	276	Shared Neighborhood Hits	207
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

TNR17_MOUSE
θ value	0.365318 (rank : 374)	NC score	0.031027 (rank : 722)
Query Neighborhood Hits	613	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	O88472	Gene names	Tnfrsf17, Bcm, Bcma
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein).

TR10A_HUMAN
θ value	0.365318 (rank : 375)	NC score	0.121861 (rank : 441)
Query Neighborhood Hits	613	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TSP2_HUMAN
θ value	0.365318 (rank : 376)	NC score	0.241785 (rank : 279)
Query Neighborhood Hits	613	Target Neighborhood Hits	359	Shared Neighborhood Hits	229
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

VLDLR_HUMAN
θ value	0.365318 (rank : 377)	NC score	0.343891 (rank : 168)
Query Neighborhood Hits	613	Target Neighborhood Hits	383	Shared Neighborhood Hits	253
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ZN189_HUMAN
θ value	0.365318 (rank : 378)	NC score	0.024591 (rank : 740)
Query Neighborhood Hits	613	Target Neighborhood Hits	754	Shared Neighborhood Hits	79
SwissProt Accessions	O75820, O75802, Q5T7D9, Q9UBL4, Q9UPE9, Q9UPF0, Q9UPF1	Gene names	ZNF189
Domain Architecture
Description	Zinc finger protein 189.

ZN682_HUMAN
θ value	0.365318 (rank : 379)	NC score	0.021983 (rank : 767)
Query Neighborhood Hits	613	Target Neighborhood Hits	779	Shared Neighborhood Hits	81
SwissProt Accessions	O95780, Q96JV9	Gene names	ZNF682
Domain Architecture	No domain graphic available
Description	Zinc finger protein 682.

ADA19_HUMAN
θ value	0.47712 (rank : 380)	NC score	0.117760 (rank : 448)
Query Neighborhood Hits	613	Target Neighborhood Hits	381	Shared Neighborhood Hits	167
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA33_MOUSE
θ value	0.47712 (rank : 381)	NC score	0.112260 (rank : 464)
Query Neighborhood Hits	613	Target Neighborhood Hits	231	Shared Neighborhood Hits	160
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CELR1_MOUSE
θ value	0.47712 (rank : 382)	NC score	0.183395 (rank : 323)
Query Neighborhood Hits	613	Target Neighborhood Hits	617	Shared Neighborhood Hits	245
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR3_MOUSE
θ value	0.47712 (rank : 383)	NC score	0.189108 (rank : 317)
Query Neighborhood Hits	613	Target Neighborhood Hits	687	Shared Neighborhood Hits	268
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

EMR1_MOUSE
θ value	0.47712 (rank : 384)	NC score	0.298254 (rank : 231)
Query Neighborhood Hits	613	Target Neighborhood Hits	349	Shared Neighborhood Hits	199
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

KRA15_HUMAN
θ value	0.47712 (rank : 385)	NC score	0.237068 (rank : 282)
Query Neighborhood Hits	613	Target Neighborhood Hits	126	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

MT1H_HUMAN
θ value	0.47712 (rank : 386)	NC score	0.160267 (rank : 357)
Query Neighborhood Hits	613	Target Neighborhood Hits	78	Shared Neighborhood Hits	67
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT1I_HUMAN
θ value	0.47712 (rank : 387)	NC score	0.125530 (rank : 430)
Query Neighborhood Hits	613	Target Neighborhood Hits	64	Shared Neighborhood Hits	56
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

NAGPA_HUMAN
θ value	0.47712 (rank : 388)	NC score	0.366323 (rank : 151)
Query Neighborhood Hits	613	Target Neighborhood Hits	282	Shared Neighborhood Hits	223
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NET1_MOUSE
θ value	0.47712 (rank : 389)	NC score	0.265474 (rank : 264)
Query Neighborhood Hits	613	Target Neighborhood Hits	151	Shared Neighborhood Hits	125
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET4_MOUSE
θ value	0.47712 (rank : 390)	NC score	0.299934 (rank : 228)
Query Neighborhood Hits	613	Target Neighborhood Hits	180	Shared Neighborhood Hits	153
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

SLIT2_MOUSE
θ value	0.47712 (rank : 391)	NC score	0.271354 (rank : 258)
Query Neighborhood Hits	613	Target Neighborhood Hits	684	Shared Neighborhood Hits	261
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TSP4_MOUSE
θ value	0.47712 (rank : 392)	NC score	0.315560 (rank : 204)
Query Neighborhood Hits	613	Target Neighborhood Hits	276	Shared Neighborhood Hits	215
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

WFDC3_HUMAN
θ value	0.47712 (rank : 393)	NC score	0.162929 (rank : 353)
Query Neighborhood Hits	613	Target Neighborhood Hits	138	Shared Neighborhood Hits	92
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

ZAN_HUMAN
θ value	0.47712 (rank : 394)	NC score	0.250295 (rank : 273)
Query Neighborhood Hits	613	Target Neighborhood Hits	679	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZN283_HUMAN
θ value	0.47712 (rank : 395)	NC score	0.022854 (rank : 759)
Query Neighborhood Hits	613	Target Neighborhood Hits	760	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N7M2	Gene names	ZNF283
Domain Architecture	No domain graphic available
Description	Zinc finger protein 283.

ZN620_HUMAN
θ value	0.47712 (rank : 396)	NC score	0.020808 (rank : 789)
Query Neighborhood Hits	613	Target Neighborhood Hits	744	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZNG0, Q8N223	Gene names	ZNF620
Domain Architecture	No domain graphic available
Description	Zinc finger protein 620.

ZN678_HUMAN
θ value	0.47712 (rank : 397)	NC score	0.023447 (rank : 751)
Query Neighborhood Hits	613	Target Neighborhood Hits	761	Shared Neighborhood Hits	87
SwissProt Accessions	Q5SXM1, Q8IVQ9	Gene names	ZNF678
Domain Architecture	No domain graphic available
Description	Zinc finger protein 678.

ADAM8_MOUSE
θ value	0.62314 (rank : 398)	NC score	0.132233 (rank : 414)
Query Neighborhood Hits	613	Target Neighborhood Hits	326	Shared Neighborhood Hits	190
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ATS3_HUMAN
θ value	0.62314 (rank : 399)	NC score	0.050034 (rank : 697)
Query Neighborhood Hits	613	Target Neighborhood Hits	179	Shared Neighborhood Hits	69
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

BAI3_HUMAN
θ value	0.62314 (rank : 400)	NC score	0.068171 (rank : 597)
Query Neighborhood Hits	613	Target Neighborhood Hits	246	Shared Neighborhood Hits	70
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

EPHB3_HUMAN
θ value	0.62314 (rank : 401)	NC score	0.053275 (rank : 680)
Query Neighborhood Hits	613	Target Neighborhood Hits	996	Shared Neighborhood Hits	83
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

GP179_HUMAN
θ value	0.62314 (rank : 402)	NC score	0.045310 (rank : 703)
Query Neighborhood Hits	613	Target Neighborhood Hits	372	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

KR103_HUMAN
θ value	0.62314 (rank : 403)	NC score	0.271723 (rank : 257)
Query Neighborhood Hits	613	Target Neighborhood Hits	212	Shared Neighborhood Hits	154
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR511_HUMAN
θ value	0.62314 (rank : 404)	NC score	0.399368 (rank : 121)
Query Neighborhood Hits	613	Target Neighborhood Hits	231	Shared Neighborhood Hits	160
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

NET4_HUMAN
θ value	0.62314 (rank : 405)	NC score	0.301504 (rank : 223)
Query Neighborhood Hits	613	Target Neighborhood Hits	191	Shared Neighborhood Hits	162
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

SLIT2_HUMAN
θ value	0.62314 (rank : 406)	NC score	0.275899 (rank : 252)
Query Neighborhood Hits	613	Target Neighborhood Hits	708	Shared Neighborhood Hits	274
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TNR3_MOUSE
θ value	0.62314 (rank : 407)	NC score	0.147505 (rank : 374)
Query Neighborhood Hits	613	Target Neighborhood Hits	113	Shared Neighborhood Hits	93
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR5_HUMAN
θ value	0.62314 (rank : 408)	NC score	0.136217 (rank : 403)
Query Neighborhood Hits	613	Target Neighborhood Hits	102	Shared Neighborhood Hits	92
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR8_HUMAN
θ value	0.62314 (rank : 409)	NC score	0.157067 (rank : 362)
Query Neighborhood Hits	613	Target Neighborhood Hits	198	Shared Neighborhood Hits	114
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

ZN101_HUMAN
θ value	0.62314 (rank : 410)	NC score	0.021064 (rank : 786)
Query Neighborhood Hits	613	Target Neighborhood Hits	731	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IZC7	Gene names	ZNF101
Domain Architecture	No domain graphic available
Description	Zinc finger protein 101 (Zinc finger protein HZF12).

ZN330_MOUSE
θ value	0.62314 (rank : 411)	NC score	0.062613 (rank : 625)
Query Neighborhood Hits	613	Target Neighborhood Hits	86	Shared Neighborhood Hits	35
SwissProt Accessions	Q922H9, Q8C389, Q8K2M4	Gene names	Znf330, Noa36, Zfp330
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

ZN669_HUMAN
θ value	0.62314 (rank : 412)	NC score	0.021444 (rank : 776)
Query Neighborhood Hits	613	Target Neighborhood Hits	746	Shared Neighborhood Hits	77
SwissProt Accessions	Q96BR6, Q5VT39, Q9H9Q6	Gene names	ZNF669
Domain Architecture	No domain graphic available
Description	Zinc finger protein 669.

ADA12_MOUSE
θ value	0.813845 (rank : 413)	NC score	0.100707 (rank : 493)
Query Neighborhood Hits	613	Target Neighborhood Hits	474	Shared Neighborhood Hits	128
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_MOUSE
θ value	0.813845 (rank : 414)	NC score	0.129573 (rank : 418)
Query Neighborhood Hits	613	Target Neighborhood Hits	324	Shared Neighborhood Hits	196
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

BAI3_MOUSE
θ value	0.813845 (rank : 415)	NC score	0.071002 (rank : 586)
Query Neighborhood Hits	613	Target Neighborhood Hits	250	Shared Neighborhood Hits	73
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

C4BP_HUMAN
θ value	0.813845 (rank : 416)	NC score	0.030604 (rank : 723)
Query Neighborhood Hits	613	Target Neighborhood Hits	92	Shared Neighborhood Hits	27
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

CELR2_MOUSE
θ value	0.813845 (rank : 417)	NC score	0.174996 (rank : 329)
Query Neighborhood Hits	613	Target Neighborhood Hits	584	Shared Neighborhood Hits	240
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

EPHA1_MOUSE
θ value	0.813845 (rank : 418)	NC score	0.061529 (rank : 634)
Query Neighborhood Hits	613	Target Neighborhood Hits	958	Shared Neighborhood Hits	109
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHAA_HUMAN
θ value	0.813845 (rank : 419)	NC score	0.062584 (rank : 626)
Query Neighborhood Hits	613	Target Neighborhood Hits	960	Shared Neighborhood Hits	87
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

MASP1_MOUSE
θ value	0.813845 (rank : 420)	NC score	0.059573 (rank : 643)
Query Neighborhood Hits	613	Target Neighborhood Hits	364	Shared Neighborhood Hits	121
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_MOUSE
θ value	0.813845 (rank : 421)	NC score	0.064718 (rank : 616)
Query Neighborhood Hits	613	Target Neighborhood Hits	382	Shared Neighborhood Hits	128
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MBTP1_HUMAN
θ value	0.813845 (rank : 422)	NC score	0.070379 (rank : 591)
Query Neighborhood Hits	613	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

MBTP1_MOUSE
θ value	0.813845 (rank : 423)	NC score	0.065682 (rank : 610)
Query Neighborhood Hits	613	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTZ2, Q6PG67	Gene names	Mbtps1, S1p, Ski1
Domain Architecture
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin isozyme 1) (SKI-1) (Sterol-regulated luminal protease).

SEM5B_HUMAN
θ value	0.813845 (rank : 424)	NC score	0.042744 (rank : 708)
Query Neighborhood Hits	613	Target Neighborhood Hits	178	Shared Neighborhood Hits	60
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

TNR5_MOUSE
θ value	0.813845 (rank : 425)	NC score	0.168609 (rank : 344)
Query Neighborhood Hits	613	Target Neighborhood Hits	131	Shared Neighborhood Hits	106
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TRI42_MOUSE
θ value	0.813845 (rank : 426)	NC score	0.057217 (rank : 656)
Query Neighborhood Hits	613	Target Neighborhood Hits	316	Shared Neighborhood Hits	82
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ZCHC4_HUMAN
θ value	0.813845 (rank : 427)	NC score	0.034140 (rank : 718)
Query Neighborhood Hits	613	Target Neighborhood Hits	76	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H5U6, Q5IW78, Q96AN7	Gene names	ZCCHC4
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 4.

ZN227_HUMAN
θ value	0.813845 (rank : 428)	NC score	0.024466 (rank : 741)
Query Neighborhood Hits	613	Target Neighborhood Hits	781	Shared Neighborhood Hits	89
SwissProt Accessions	Q86WZ6	Gene names	ZNF227
Domain Architecture	No domain graphic available
Description	Zinc finger protein 227.

ZN439_HUMAN
θ value	0.813845 (rank : 429)	NC score	0.022100 (rank : 764)
Query Neighborhood Hits	613	Target Neighborhood Hits	763	Shared Neighborhood Hits	81
SwissProt Accessions	Q8NDP4, Q8IYZ7, Q96SU1	Gene names	ZNF439
Domain Architecture
Description	Zinc finger protein 439.

ADAM7_HUMAN
θ value	1.06291 (rank : 430)	NC score	0.110346 (rank : 467)
Query Neighborhood Hits	613	Target Neighborhood Hits	221	Shared Neighborhood Hits	165
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ATS12_HUMAN
θ value	1.06291 (rank : 431)	NC score	0.049740 (rank : 698)
Query Neighborhood Hits	613	Target Neighborhood Hits	251	Shared Neighborhood Hits	79
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

CD97_HUMAN
θ value	1.06291 (rank : 432)	NC score	0.298004 (rank : 232)
Query Neighborhood Hits	613	Target Neighborhood Hits	353	Shared Neighborhood Hits	210
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CNBP_HUMAN
θ value	1.06291 (rank : 433)	NC score	0.040706 (rank : 713)
Query Neighborhood Hits	613	Target Neighborhood Hits	196	Shared Neighborhood Hits	46
SwissProt Accessions	P62633, P20694, Q5QJR0, Q6PJI7, Q96NV3	Gene names	CNBP, ZNF9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

EPHB1_HUMAN
θ value	1.06291 (rank : 434)	NC score	0.053587 (rank : 678)
Query Neighborhood Hits	613	Target Neighborhood Hits	988	Shared Neighborhood Hits	100
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

LCE2A_HUMAN
θ value	1.06291 (rank : 435)	NC score	0.174405 (rank : 331)
Query Neighborhood Hits	613	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LYAM3_HUMAN
θ value	1.06291 (rank : 436)	NC score	0.201129 (rank : 303)
Query Neighborhood Hits	613	Target Neighborhood Hits	378	Shared Neighborhood Hits	205
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

NET1_HUMAN
θ value	1.06291 (rank : 437)	NC score	0.267229 (rank : 262)
Query Neighborhood Hits	613	Target Neighborhood Hits	149	Shared Neighborhood Hits	123
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

TMPS7_HUMAN
θ value	1.06291 (rank : 438)	NC score	0.039823 (rank : 715)
Query Neighborhood Hits	613	Target Neighborhood Hits	275	Shared Neighborhood Hits	65
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	1.06291 (rank : 439)	NC score	0.041276 (rank : 712)
Query Neighborhood Hits	613	Target Neighborhood Hits	275	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TNR6B_HUMAN
θ value	1.06291 (rank : 440)	NC score	0.153094 (rank : 368)
Query Neighborhood Hits	613	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

ZFP60_MOUSE
θ value	1.06291 (rank : 441)	NC score	0.022035 (rank : 765)
Query Neighborhood Hits	613	Target Neighborhood Hits	754	Shared Neighborhood Hits	79
SwissProt Accessions	P16374, Q61135	Gene names	Zfp60, Mfg3
Domain Architecture
Description	Zinc finger protein 60 (Zfp-60) (Zinc finger protein Mfg-3).

ZN330_HUMAN
θ value	1.06291 (rank : 442)	NC score	0.072372 (rank : 583)
Query Neighborhood Hits	613	Target Neighborhood Hits	83	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

ZN605_HUMAN
θ value	1.06291 (rank : 443)	NC score	0.021520 (rank : 775)
Query Neighborhood Hits	613	Target Neighborhood Hits	753	Shared Neighborhood Hits	77
SwissProt Accessions	Q86T29, Q86T91	Gene names	ZNF605
Domain Architecture	No domain graphic available
Description	Zinc finger protein 605.

ADA21_HUMAN
θ value	1.38821 (rank : 444)	NC score	0.088776 (rank : 534)
Query Neighborhood Hits	613	Target Neighborhood Hits	181	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA33_HUMAN
θ value	1.38821 (rank : 445)	NC score	0.114616 (rank : 456)
Query Neighborhood Hits	613	Target Neighborhood Hits	264	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CD248_HUMAN
θ value	1.38821 (rank : 446)	NC score	0.304369 (rank : 218)
Query Neighborhood Hits	613	Target Neighborhood Hits	679	Shared Neighborhood Hits	211
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CELR1_HUMAN
θ value	1.38821 (rank : 447)	NC score	0.182970 (rank : 324)
Query Neighborhood Hits	613	Target Neighborhood Hits	613	Shared Neighborhood Hits	240
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR3_HUMAN
θ value	1.38821 (rank : 448)	NC score	0.188500 (rank : 318)
Query Neighborhood Hits	613	Target Neighborhood Hits	680	Shared Neighborhood Hits	261
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

EMR2_HUMAN
θ value	1.38821 (rank : 449)	NC score	0.300321 (rank : 227)
Query Neighborhood Hits	613	Target Neighborhood Hits	345	Shared Neighborhood Hits	206
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FAM5C_HUMAN
θ value	1.38821 (rank : 450)	NC score	0.023858 (rank : 748)
Query Neighborhood Hits	613	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q76B58, O95726	Gene names	FAM5C, DBCCR1L, DBCCR1L1
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor (DBCCR1-like protein 1).

FAM5C_MOUSE
θ value	1.38821 (rank : 451)	NC score	0.023897 (rank : 746)
Query Neighborhood Hits	613	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q499E0, Q8K0R9	Gene names	Fam5c
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor.

FHR4_HUMAN
θ value	1.38821 (rank : 452)	NC score	0.022017 (rank : 766)
Query Neighborhood Hits	613	Target Neighborhood Hits	75	Shared Neighborhood Hits	25
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

ITB6_HUMAN
θ value	1.38821 (rank : 453)	NC score	0.324264 (rank : 191)
Query Neighborhood Hits	613	Target Neighborhood Hits	318	Shared Neighborhood Hits	249
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

MKS3_MOUSE
θ value	1.38821 (rank : 454)	NC score	0.133590 (rank : 410)
Query Neighborhood Hits	613	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

SLIT3_HUMAN
θ value	1.38821 (rank : 455)	NC score	0.265886 (rank : 263)
Query Neighborhood Hits	613	Target Neighborhood Hits	682	Shared Neighborhood Hits	261
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
θ value	1.38821 (rank : 456)	NC score	0.273247 (rank : 256)
Query Neighborhood Hits	613	Target Neighborhood Hits	700	Shared Neighborhood Hits	274
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TR13B_MOUSE
θ value	1.38821 (rank : 457)	NC score	0.058738 (rank : 650)
Query Neighborhood Hits	613	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ET35, Q9DBZ3	Gene names	Tnfrsf13b, Taci
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor).

VLDLR_MOUSE
θ value	1.38821 (rank : 458)	NC score	0.339468 (rank : 174)
Query Neighborhood Hits	613	Target Neighborhood Hits	360	Shared Neighborhood Hits	239
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

BMP1_HUMAN
θ value	1.81305 (rank : 459)	NC score	0.148686 (rank : 373)
Query Neighborhood Hits	613	Target Neighborhood Hits	233	Shared Neighborhood Hits	140
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	1.81305 (rank : 460)	NC score	0.149565 (rank : 372)
Query Neighborhood Hits	613	Target Neighborhood Hits	236	Shared Neighborhood Hits	141
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

KR132_HUMAN
θ value	1.81305 (rank : 461)	NC score	0.070728 (rank : 588)
Query Neighborhood Hits	613	Target Neighborhood Hits	69	Shared Neighborhood Hits	47
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

KRA42_HUMAN
θ value	1.81305 (rank : 462)	NC score	0.222308 (rank : 291)
Query Neighborhood Hits	613	Target Neighborhood Hits	149	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

TEFF2_HUMAN
θ value	1.81305 (rank : 463)	NC score	0.162944 (rank : 352)
Query Neighborhood Hits	613	Target Neighborhood Hits	211	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	1.81305 (rank : 464)	NC score	0.164755 (rank : 349)
Query Neighborhood Hits	613	Target Neighborhood Hits	214	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TLL2_MOUSE
θ value	1.81305 (rank : 465)	NC score	0.139379 (rank : 395)
Query Neighborhood Hits	613	Target Neighborhood Hits	240	Shared Neighborhood Hits	139
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TNR6_HUMAN
θ value	1.81305 (rank : 466)	NC score	0.133426 (rank : 411)
Query Neighborhood Hits	613	Target Neighborhood Hits	95	Shared Neighborhood Hits	78
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
θ value	1.81305 (rank : 467)	NC score	0.152163 (rank : 369)
Query Neighborhood Hits	613	Target Neighborhood Hits	99	Shared Neighborhood Hits	88
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TS1R2_MOUSE
θ value	1.81305 (rank : 468)	NC score	0.007073 (rank : 834)
Query Neighborhood Hits	613	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TYRP1_HUMAN
θ value	1.81305 (rank : 469)	NC score	0.033845 (rank : 719)
Query Neighborhood Hits	613	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P17643, P78468, P78469, Q13721, Q15679	Gene names	TYRP1, CAS2, TYRP, TYRRP
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75).

ZFN2B_HUMAN
θ value	1.81305 (rank : 470)	NC score	0.018318 (rank : 809)
Query Neighborhood Hits	613	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WV99, Q8NB98	Gene names	ZFAND2B
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 2B.

ZMYM6_HUMAN
θ value	1.81305 (rank : 471)	NC score	0.019118 (rank : 804)
Query Neighborhood Hits	613	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	O95789, Q96IY0	Gene names	ZMYM6, ZNF258
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 6 (Zinc finger protein 258).

ZN418_HUMAN
θ value	1.81305 (rank : 472)	NC score	0.022887 (rank : 758)
Query Neighborhood Hits	613	Target Neighborhood Hits	776	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TF45, Q670L5, Q96N18	Gene names	ZNF418, KIAA1956
Domain Architecture
Description	Zinc finger protein 418.

ZN432_HUMAN
θ value	1.81305 (rank : 473)	NC score	0.021595 (rank : 774)
Query Neighborhood Hits	613	Target Neighborhood Hits	764	Shared Neighborhood Hits	77
SwissProt Accessions	O94892	Gene names	ZNF432, KIAA0798
Domain Architecture
Description	Zinc finger protein 432.

ZNF14_HUMAN
θ value	1.81305 (rank : 474)	NC score	0.021923 (rank : 770)
Query Neighborhood Hits	613	Target Neighborhood Hits	760	Shared Neighborhood Hits	78
SwissProt Accessions	P17017, Q9ULZ5	Gene names	ZNF14, GIOT4, KOX6
Domain Architecture
Description	Zinc finger protein 14 (Zinc finger protein KOX6) (Gonadotropin- inducible transcription repressor 4) (GIOT-4).

AIRE_MOUSE
θ value	2.36792 (rank : 475)	NC score	0.024195 (rank : 744)
Query Neighborhood Hits	613	Target Neighborhood Hits	196	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

ARI2_HUMAN
θ value	2.36792 (rank : 476)	NC score	0.011353 (rank : 818)
Query Neighborhood Hits	613	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ATS20_HUMAN
θ value	2.36792 (rank : 477)	NC score	0.062065 (rank : 628)
Query Neighborhood Hits	613	Target Neighborhood Hits	192	Shared Neighborhood Hits	89
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

CRIS1_MOUSE
θ value	2.36792 (rank : 478)	NC score	0.008783 (rank : 825)
Query Neighborhood Hits	613	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q03401	Gene names	Crisp1, Aeg-1, Aeg1
Domain Architecture
Description	Cysteine-rich secretory protein 1 precursor (CRISP-1) (Acidic epididymal glycoprotein 1) (Sperm-coating glycoprotein 1) (SCP 1).

CSPG3_MOUSE
θ value	2.36792 (rank : 479)	NC score	0.201783 (rank : 301)
Query Neighborhood Hits	613	Target Neighborhood Hits	657	Shared Neighborhood Hits	207
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

KRA11_HUMAN
θ value	2.36792 (rank : 480)	NC score	0.268261 (rank : 261)
Query Neighborhood Hits	613	Target Neighborhood Hits	155	Shared Neighborhood Hits	118
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

LCE2D_HUMAN
θ value	2.36792 (rank : 481)	NC score	0.171638 (rank : 338)
Query Neighborhood Hits	613	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

MSRX_MOUSE
θ value	2.36792 (rank : 482)	NC score	0.015748 (rank : 814)
Query Neighborhood Hits	613	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLC3	Gene names	Sepx1, Sepr
Domain Architecture
Description	Methionine-R-sulfoxide reductase (EC 1.8.4.-) (Selenoprotein X 1) (Selenoprotein R).

MT1M_HUMAN
θ value	2.36792 (rank : 483)	NC score	0.112860 (rank : 462)
Query Neighborhood Hits	613	Target Neighborhood Hits	72	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

PAPPA_MOUSE
θ value	2.36792 (rank : 484)	NC score	0.096105 (rank : 511)
Query Neighborhood Hits	613	Target Neighborhood Hits	153	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

RORB_HUMAN
θ value	2.36792 (rank : 485)	NC score	0.003432 (rank : 842)
Query Neighborhood Hits	613	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_MOUSE
θ value	2.36792 (rank : 486)	NC score	0.003453 (rank : 841)
Query Neighborhood Hits	613	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

TENR_MOUSE
θ value	2.36792 (rank : 487)	NC score	0.262251 (rank : 267)
Query Neighborhood Hits	613	Target Neighborhood Hits	531	Shared Neighborhood Hits	267
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TLL1_HUMAN
θ value	2.36792 (rank : 488)	NC score	0.139356 (rank : 396)
Query Neighborhood Hits	613	Target Neighborhood Hits	236	Shared Neighborhood Hits	137
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

WFDC8_HUMAN
θ value	2.36792 (rank : 489)	NC score	0.032372 (rank : 721)
Query Neighborhood Hits	613	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

ZFYV1_HUMAN
θ value	2.36792 (rank : 490)	NC score	0.010857 (rank : 820)
Query Neighborhood Hits	613	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

ZN154_HUMAN
θ value	2.36792 (rank : 491)	NC score	0.020494 (rank : 795)
Query Neighborhood Hits	613	Target Neighborhood Hits	734	Shared Neighborhood Hits	77
SwissProt Accessions	Q13106, Q8IVG7, Q8NAR0	Gene names	ZNF154, KIAA2003
Domain Architecture	No domain graphic available
Description	Zinc finger protein 154.

ZN260_HUMAN
θ value	2.36792 (rank : 492)	NC score	0.020662 (rank : 792)
Query Neighborhood Hits	613	Target Neighborhood Hits	757	Shared Neighborhood Hits	78
SwissProt Accessions	Q3ZCT1	Gene names	ZNF260, ZFP260
Domain Architecture	No domain graphic available
Description	Zinc finger protein 260 (Zfp-260).

ZN419_HUMAN
θ value	2.36792 (rank : 493)	NC score	0.020023 (rank : 800)
Query Neighborhood Hits	613	Target Neighborhood Hits	745	Shared Neighborhood Hits	76
SwissProt Accessions	Q96HQ0, Q9H5P0	Gene names	ZNF419A, ZNF419
Domain Architecture	No domain graphic available
Description	Zinc finger protein 419A.

ZN440_HUMAN
θ value	2.36792 (rank : 494)	NC score	0.020725 (rank : 790)
Query Neighborhood Hits	613	Target Neighborhood Hits	750	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IYI8, Q8N1R9	Gene names	ZNF440
Domain Architecture
Description	Zinc finger protein 440.

ZN490_HUMAN
θ value	2.36792 (rank : 495)	NC score	0.021226 (rank : 780)
Query Neighborhood Hits	613	Target Neighborhood Hits	754	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ULM2	Gene names	ZNF490, KIAA1198
Domain Architecture
Description	Zinc finger protein 490.

ADAM9_HUMAN
θ value	3.0926 (rank : 496)	NC score	0.107987 (rank : 469)
Query Neighborhood Hits	613	Target Neighborhood Hits	243	Shared Neighborhood Hits	171
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

AHI1_HUMAN
θ value	3.0926 (rank : 497)	NC score	-0.004578 (rank : 849)
Query Neighborhood Hits	613	Target Neighborhood Hits	537	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

ARI2_MOUSE
θ value	3.0926 (rank : 498)	NC score	0.010967 (rank : 819)
Query Neighborhood Hits	613	Target Neighborhood Hits	106	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

CHD3_HUMAN
θ value	3.0926 (rank : 499)	NC score	0.007413 (rank : 831)
Query Neighborhood Hits	613	Target Neighborhood Hits	397	Shared Neighborhood Hits	20
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CTCF_HUMAN
θ value	3.0926 (rank : 500)	NC score	0.018655 (rank : 808)
Query Neighborhood Hits	613	Target Neighborhood Hits	764	Shared Neighborhood Hits	68
SwissProt Accessions	P49711	Gene names	CTCF
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

CTCF_MOUSE
θ value	3.0926 (rank : 501)	NC score	0.018785 (rank : 807)
Query Neighborhood Hits	613	Target Neighborhood Hits	796	Shared Neighborhood Hits	71
SwissProt Accessions	Q61164	Gene names	Ctcf
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

KR171_HUMAN
θ value	3.0926 (rank : 502)	NC score	0.344457 (rank : 167)
Query Neighborhood Hits	613	Target Neighborhood Hits	144	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KRA99_HUMAN
θ value	3.0926 (rank : 503)	NC score	0.271155 (rank : 259)
Query Neighborhood Hits	613	Target Neighborhood Hits	173	Shared Neighborhood Hits	134
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LRP6_HUMAN
θ value	3.0926 (rank : 504)	NC score	0.177163 (rank : 326)
Query Neighborhood Hits	613	Target Neighborhood Hits	235	Shared Neighborhood Hits	138
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MDFI_HUMAN
θ value	3.0926 (rank : 505)	NC score	0.024226 (rank : 743)
Query Neighborhood Hits	613	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	Q99750	Gene names	MDFI
Domain Architecture	No domain graphic available
Description	MyoD family inhibitor (Myogenic repressor I-mf).

PHF7_HUMAN
θ value	3.0926 (rank : 506)	NC score	0.036619 (rank : 717)
Query Neighborhood Hits	613	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

RIN1_MOUSE
θ value	3.0926 (rank : 507)	NC score	0.006763 (rank : 835)
Query Neighborhood Hits	613	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).

RORA_HUMAN
θ value	3.0926 (rank : 508)	NC score	0.003180 (rank : 844)
Query Neighborhood Hits	613	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORA_MOUSE
θ value	3.0926 (rank : 509)	NC score	0.003381 (rank : 843)
Query Neighborhood Hits	613	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RSNB_MOUSE
θ value	3.0926 (rank : 510)	NC score	0.013560 (rank : 817)
Query Neighborhood Hits	613	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P86, Q9D286	Gene names	Retnlb, Fizz2
Domain Architecture
Description	Resistin-like beta precursor (RELMbeta) (Cysteine-rich secreted protein FIZZ2) (Cysteine-rich secreted protein A12-beta).

TCF17_HUMAN
θ value	3.0926 (rank : 511)	NC score	0.021927 (rank : 769)
Query Neighborhood Hits	613	Target Neighborhood Hits	797	Shared Neighborhood Hits	88
SwissProt Accessions	O60765, Q9UNJ8	Gene names	ZNF354A, EZNF, HKL1, TCF17
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF).

TES_HUMAN
θ value	3.0926 (rank : 512)	NC score	0.018850 (rank : 805)
Query Neighborhood Hits	613	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UGI8, Q9GZQ1, Q9HAJ9	Gene names	TES
Domain Architecture
Description	Testin (TESS).

THYG_MOUSE
θ value	3.0926 (rank : 513)	NC score	0.050252 (rank : 695)
Query Neighborhood Hits	613	Target Neighborhood Hits	161	Shared Neighborhood Hits	77
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TLL1_MOUSE
θ value	3.0926 (rank : 514)	NC score	0.142375 (rank : 388)
Query Neighborhood Hits	613	Target Neighborhood Hits	237	Shared Neighborhood Hits	140
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TNR27_HUMAN
θ value	3.0926 (rank : 515)	NC score	0.074237 (rank : 575)
Query Neighborhood Hits	613	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TTY6_HUMAN
θ value	3.0926 (rank : 516)	NC score	0.023550 (rank : 750)
Query Neighborhood Hits	613	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXH5	Gene names	TTTY6, TTY6
Domain Architecture	No domain graphic available
Description	Transcript Y 6 protein.

ZN563_HUMAN
θ value	3.0926 (rank : 517)	NC score	0.021437 (rank : 777)
Query Neighborhood Hits	613	Target Neighborhood Hits	754	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TA94, Q8NAT7	Gene names	ZNF563
Domain Architecture	No domain graphic available
Description	Zinc finger protein 563.

ADA24_MOUSE
θ value	4.03905 (rank : 518)	NC score	0.091000 (rank : 525)
Query Neighborhood Hits	613	Target Neighborhood Hits	230	Shared Neighborhood Hits	160
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADAM8_HUMAN
θ value	4.03905 (rank : 519)	NC score	0.129643 (rank : 417)
Query Neighborhood Hits	613	Target Neighborhood Hits	327	Shared Neighborhood Hits	199
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ATL3_HUMAN
θ value	4.03905 (rank : 520)	NC score	0.050989 (rank : 689)
Query Neighborhood Hits	613	Target Neighborhood Hits	414	Shared Neighborhood Hits	64
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATS5_HUMAN
θ value	4.03905 (rank : 521)	NC score	0.041888 (rank : 710)
Query Neighborhood Hits	613	Target Neighborhood Hits	141	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

EDAR_HUMAN
θ value	4.03905 (rank : 522)	NC score	0.052483 (rank : 684)
Query Neighborhood Hits	613	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

ENPP3_HUMAN
θ value	4.03905 (rank : 523)	NC score	0.007086 (rank : 833)
Query Neighborhood Hits	613	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	O14638	Gene names	ENPP3, PDNP3
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP 3) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (Phosphodiesterase I beta) (PD-Ibeta) (CD203c antigen) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ENTK_MOUSE
θ value	4.03905 (rank : 524)	NC score	0.028003 (rank : 729)
Query Neighborhood Hits	613	Target Neighborhood Hits	338	Shared Neighborhood Hits	57
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

EPHA7_HUMAN
θ value	4.03905 (rank : 525)	NC score	0.062567 (rank : 627)
Query Neighborhood Hits	613	Target Neighborhood Hits	1053	Shared Neighborhood Hits	137
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

KR10C_HUMAN
θ value	4.03905 (rank : 526)	NC score	0.306399 (rank : 216)
Query Neighborhood Hits	613	Target Neighborhood Hits	219	Shared Neighborhood Hits	164
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

LCE2C_HUMAN
θ value	4.03905 (rank : 527)	NC score	0.174211 (rank : 332)
Query Neighborhood Hits	613	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

MASP1_HUMAN
θ value	4.03905 (rank : 528)	NC score	0.060483 (rank : 635)
Query Neighborhood Hits	613	Target Neighborhood Hits	369	Shared Neighborhood Hits	121
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

PCSK9_HUMAN
θ value	4.03905 (rank : 529)	NC score	0.048122 (rank : 700)
Query Neighborhood Hits	613	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NBP7, Q5PSM5	Gene names	PCSK9, NARC1
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 9 precursor (EC 3.4.21.-) (Proprotein convertase PC9) (Subtilisin/kexin-like protease PC9) (Neural apoptosis-regulated convertase 1) (NARC-1).

SEM5A_HUMAN
θ value	4.03905 (rank : 530)	NC score	0.041350 (rank : 711)
Query Neighborhood Hits	613	Target Neighborhood Hits	177	Shared Neighborhood Hits	60
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SLIT1_MOUSE
θ value	4.03905 (rank : 531)	NC score	0.286867 (rank : 240)
Query Neighborhood Hits	613	Target Neighborhood Hits	715	Shared Neighborhood Hits	278
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

TCF17_MOUSE
θ value	4.03905 (rank : 532)	NC score	0.020574 (rank : 794)
Query Neighborhood Hits	613	Target Neighborhood Hits	786	Shared Neighborhood Hits	77
SwissProt Accessions	Q61751	Gene names	Znf354a, Kid1, Tcf17, Zfp354a
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Renal transcription factor Kid-1) (Kidney, ischemia, and developmentally- regulated protein 1).

TNR17_HUMAN
θ value	4.03905 (rank : 533)	NC score	0.021935 (rank : 768)
Query Neighborhood Hits	613	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q02223	Gene names	TNFRSF17, BCM, BCMA
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD269 antigen).

UN84A_MOUSE
θ value	4.03905 (rank : 534)	NC score	0.008139 (rank : 829)
Query Neighborhood Hits	613	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D666, Q80SU8, Q8BZ99, Q99P23	Gene names	Unc84a, Sun1
Domain Architecture	No domain graphic available
Description	Sad1/unc-84 protein-like 1 (Unc-84 homolog A).

ZFN2B_MOUSE
θ value	4.03905 (rank : 535)	NC score	0.015436 (rank : 815)
Query Neighborhood Hits	613	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q91X58, Q9D0W4	Gene names	Zfand2b
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 2B.

ZFP59_MOUSE
θ value	4.03905 (rank : 536)	NC score	0.021087 (rank : 784)
Query Neighborhood Hits	613	Target Neighborhood Hits	768	Shared Neighborhood Hits	79
SwissProt Accessions	P16373, Q61849	Gene names	Zfp59, Mfg2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 59 (Zfp-59) (Zinc finger protein Mfg-2).

ZN208_HUMAN
θ value	4.03905 (rank : 537)	NC score	0.022990 (rank : 757)
Query Neighborhood Hits	613	Target Neighborhood Hits	771	Shared Neighborhood Hits	88
SwissProt Accessions	O43345	Gene names	ZNF208, ZNF91L
Domain Architecture
Description	Zinc finger protein 208.

ZN559_HUMAN
θ value	4.03905 (rank : 538)	NC score	0.019606 (rank : 801)
Query Neighborhood Hits	613	Target Neighborhood Hits	746	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BR84	Gene names	ZNF559
Domain Architecture	No domain graphic available
Description	Zinc finger protein 559.

ZN583_MOUSE
θ value	4.03905 (rank : 539)	NC score	0.020187 (rank : 798)
Query Neighborhood Hits	613	Target Neighborhood Hits	774	Shared Neighborhood Hits	79
SwissProt Accessions	Q3V080, Q3V3L4	Gene names	Znf583, Zfp583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583.

ADA17_HUMAN
θ value	5.27518 (rank : 540)	NC score	0.124910 (rank : 432)
Query Neighborhood Hits	613	Target Neighborhood Hits	223	Shared Neighborhood Hits	154
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA23_MOUSE
θ value	5.27518 (rank : 541)	NC score	0.118958 (rank : 447)
Query Neighborhood Hits	613	Target Neighborhood Hits	245	Shared Neighborhood Hits	175
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

AIRE_HUMAN
θ value	5.27518 (rank : 542)	NC score	0.022446 (rank : 761)
Query Neighborhood Hits	613	Target Neighborhood Hits	144	Shared Neighborhood Hits	17
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

CD248_MOUSE
θ value	5.27518 (rank : 543)	NC score	0.301747 (rank : 221)
Query Neighborhood Hits	613	Target Neighborhood Hits	578	Shared Neighborhood Hits	193
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CFAH_HUMAN
θ value	5.27518 (rank : 544)	NC score	0.025125 (rank : 737)
Query Neighborhood Hits	613	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CO6_HUMAN
θ value	5.27518 (rank : 545)	NC score	0.129938 (rank : 416)
Query Neighborhood Hits	613	Target Neighborhood Hits	331	Shared Neighborhood Hits	168
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CSPG3_HUMAN
θ value	5.27518 (rank : 546)	NC score	0.197842 (rank : 309)
Query Neighborhood Hits	613	Target Neighborhood Hits	676	Shared Neighborhood Hits	203
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DGKB_HUMAN
θ value	5.27518 (rank : 547)	NC score	0.005485 (rank : 836)
Query Neighborhood Hits	613	Target Neighborhood Hits	238	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

EGFL8_MOUSE
θ value	5.27518 (rank : 548)	NC score	0.301009 (rank : 226)
Query Neighborhood Hits	613	Target Neighborhood Hits	266	Shared Neighborhood Hits	191
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EPHA7_MOUSE
θ value	5.27518 (rank : 549)	NC score	0.055392 (rank : 667)
Query Neighborhood Hits	613	Target Neighborhood Hits	1025	Shared Neighborhood Hits	113
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

FAM5A_HUMAN
θ value	5.27518 (rank : 550)	NC score	0.015952 (rank : 812)
Query Neighborhood Hits	613	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	O60477, Q6IPV6, Q6P1A0, Q8WU22	Gene names	FAM5A, DBC1, DBCCR1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein).

FAM5A_MOUSE
θ value	5.27518 (rank : 551)	NC score	0.015953 (rank : 811)
Query Neighborhood Hits	613	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q920P3, Q80ZL2, Q812F0, Q8C1C9, Q920P4, Q9QXL0	Gene names	Fam5a, Brinp, Brinp1, Dbccr1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein homolog) (BMP/retinoic acid-inducible neural-specific protein 1).

FAM5B_MOUSE
θ value	5.27518 (rank : 552)	NC score	0.038366 (rank : 716)
Query Neighborhood Hits	613	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

KRA94_HUMAN
θ value	5.27518 (rank : 553)	NC score	0.296035 (rank : 233)
Query Neighborhood Hits	613	Target Neighborhood Hits	204	Shared Neighborhood Hits	167
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

MARH3_HUMAN
θ value	5.27518 (rank : 554)	NC score	0.008451 (rank : 828)
Query Neighborhood Hits	613	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UD3	Gene names	MARCH3, RNF173
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 3 (Membrane-associated RING-CH protein III) (MARCH-III) (RING finger protein 173).

MARH3_MOUSE
θ value	5.27518 (rank : 555)	NC score	0.008702 (rank : 826)
Query Neighborhood Hits	613	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BRX9	Gene names	March3
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 3 (Membrane-associated RING-CH protein III) (MARCH-III).

PARC_MOUSE
θ value	5.27518 (rank : 556)	NC score	0.010764 (rank : 821)
Query Neighborhood Hits	613	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

PINC_HUMAN
θ value	5.27518 (rank : 557)	NC score	0.028098 (rank : 728)
Query Neighborhood Hits	613	Target Neighborhood Hits	231	Shared Neighborhood Hits	29
SwissProt Accessions	P48059, Q53TE0, Q9BS44	Gene names	LIMS1
Domain Architecture
Description	Protein PINCH (Particularly interesting new Cys-His protein) (LIM and senescent cell antigen-like domains 1) (NY-REN-48 antigen).

TR19L_MOUSE
θ value	5.27518 (rank : 558)	NC score	0.075195 (rank : 570)
Query Neighborhood Hits	613	Target Neighborhood Hits	85	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

UPAR_HUMAN
θ value	5.27518 (rank : 559)	NC score	0.009337 (rank : 824)
Query Neighborhood Hits	613	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q03405, Q12876, Q15845, Q16887, Q9NYC8, Q9UD69, Q9UEA6, Q9UM92, Q9UMV0	Gene names	PLAUR, MO3, UPAR
Domain Architecture
Description	Urokinase plasminogen activator surface receptor precursor (uPAR) (U- PAR) (Monocyte activation antigen Mo3) (CD87 antigen).

V2R1B_MOUSE
θ value	5.27518 (rank : 560)	NC score	0.005460 (rank : 837)
Query Neighborhood Hits	613	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

ZMY10_HUMAN
θ value	5.27518 (rank : 561)	NC score	0.007167 (rank : 832)
Query Neighborhood Hits	613	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	O75800, O14570, O75801, Q8N4R6, Q8NDN6	Gene names	ZMYND10, BLU
Domain Architecture
Description	Zinc finger MYND domain-containing protein 10 (BLu protein).

ZN318_MOUSE
θ value	5.27518 (rank : 562)	NC score	-0.000584 (rank : 848)
Query Neighborhood Hits	613	Target Neighborhood Hits	642	Shared Neighborhood Hits	9
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ZN394_HUMAN
θ value	5.27518 (rank : 563)	NC score	0.017201 (rank : 810)
Query Neighborhood Hits	613	Target Neighborhood Hits	752	Shared Neighborhood Hits	69
SwissProt Accessions	Q53GI3, Q6P5X9, Q8TB27, Q9HA37	Gene names	ZNF394
Domain Architecture	No domain graphic available
Description	Zinc finger protein 394.

ZN561_HUMAN
θ value	5.27518 (rank : 564)	NC score	0.019598 (rank : 802)
Query Neighborhood Hits	613	Target Neighborhood Hits	734	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N587, Q6PJS0	Gene names	ZNF561
Domain Architecture	No domain graphic available
Description	Zinc finger protein 561.

ZN581_HUMAN
θ value	5.27518 (rank : 565)	NC score	0.015758 (rank : 813)
Query Neighborhood Hits	613	Target Neighborhood Hits	699	Shared Neighborhood Hits	65
SwissProt Accessions	Q9P0T4	Gene names	ZNF581
Domain Architecture	No domain graphic available
Description	Zinc finger protein 581.

ZSCA2_HUMAN
θ value	5.27518 (rank : 566)	NC score	0.021209 (rank : 782)
Query Neighborhood Hits	613	Target Neighborhood Hits	803	Shared Neighborhood Hits	86
SwissProt Accessions	Q7Z7L9, Q6ZQY9, Q9NWU4	Gene names	ZSCAN2, ZFP29
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29 homolog) (Zfp-29).

CDCA7_HUMAN
θ value	6.88961 (rank : 567)	NC score	0.008454 (rank : 827)
Query Neighborhood Hits	613	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWT1, Q53EW5, Q580W9, Q658K4, Q658N4, Q8NBY9, Q96BV8, Q96SP5	Gene names	CDCA7, JPO1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated protein 7 (Protein JPO1).

CNBP_MOUSE
θ value	6.88961 (rank : 568)	NC score	0.029879 (rank : 726)
Query Neighborhood Hits	613	Target Neighborhood Hits	215	Shared Neighborhood Hits	42
SwissProt Accessions	P53996, Q80Y06, Q8BP23	Gene names	Cnbp, Cnbp1, Znf9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

CSMD2_HUMAN
θ value	6.88961 (rank : 569)	NC score	0.044657 (rank : 704)
Query Neighborhood Hits	613	Target Neighborhood Hits	188	Shared Neighborhood Hits	56
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSPG2_MOUSE
θ value	6.88961 (rank : 570)	NC score	0.206153 (rank : 300)
Query Neighborhood Hits	613	Target Neighborhood Hits	711	Shared Neighborhood Hits	209
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

DCTN4_HUMAN
θ value	6.88961 (rank : 571)	NC score	0.009878 (rank : 822)
Query Neighborhood Hits	613	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJW0, Q8TAN8	Gene names	DCTN4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

DCTN4_MOUSE
θ value	6.88961 (rank : 572)	NC score	0.009535 (rank : 823)
Query Neighborhood Hits	613	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CBY8, Q923A0, Q9D4X0	Gene names	Dctn4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

DGKQ_HUMAN
θ value	6.88961 (rank : 573)	NC score	0.004326 (rank : 839)
Query Neighborhood Hits	613	Target Neighborhood Hits	131	Shared Neighborhood Hits	12
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

ESM1_MOUSE
θ value	6.88961 (rank : 574)	NC score	0.134687 (rank : 407)
Query Neighborhood Hits	613	Target Neighborhood Hits	107	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA10_MOUSE
θ value	6.88961 (rank : 575)	NC score	0.124301 (rank : 433)
Query Neighborhood Hits	613	Target Neighborhood Hits	435	Shared Neighborhood Hits	194
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

KRA33_HUMAN
θ value	6.88961 (rank : 576)	NC score	0.040412 (rank : 714)
Query Neighborhood Hits	613	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYR6, Q52LP0	Gene names	KRTAP3-3, KAP3.3, KRTAP3.3
Domain Architecture
Description	Keratin-associated protein 3-3 (Keratin-associated protein 3.3) (High sulfur keratin-associated protein 3.3).

LCE2B_HUMAN
θ value	6.88961 (rank : 577)	NC score	0.163242 (rank : 351)
Query Neighborhood Hits	613	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

PGCA_HUMAN
θ value	6.88961 (rank : 578)	NC score	0.083459 (rank : 541)
Query Neighborhood Hits	613	Target Neighborhood Hits	821	Shared Neighborhood Hits	148
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PROC_MOUSE
θ value	6.88961 (rank : 579)	NC score	0.123181 (rank : 434)
Query Neighborhood Hits	613	Target Neighborhood Hits	426	Shared Neighborhood Hits	202
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

TNR11_HUMAN
θ value	6.88961 (rank : 580)	NC score	0.147148 (rank : 375)
Query Neighborhood Hits	613	Target Neighborhood Hits	135	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TRI36_MOUSE
θ value	6.88961 (rank : 581)	NC score	0.002092 (rank : 846)
Query Neighborhood Hits	613	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

UB7I4_MOUSE
θ value	6.88961 (rank : 582)	NC score	0.004993 (rank : 838)
Query Neighborhood Hits	613	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

ZN211_HUMAN
θ value	6.88961 (rank : 583)	NC score	0.020822 (rank : 788)
Query Neighborhood Hits	613	Target Neighborhood Hits	733	Shared Neighborhood Hits	77
SwissProt Accessions	Q13398	Gene names	ZNF211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 211 (Zinc finger protein C2H2-25).

ZN319_HUMAN
θ value	6.88961 (rank : 584)	NC score	0.021909 (rank : 771)
Query Neighborhood Hits	613	Target Neighborhood Hits	772	Shared Neighborhood Hits	78
SwissProt Accessions	Q9P2F9	Gene names	ZNF319, KIAA1388
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

ZN337_HUMAN
θ value	6.88961 (rank : 585)	NC score	0.021234 (rank : 779)
Query Neighborhood Hits	613	Target Neighborhood Hits	781	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y3M9, Q9Y3Y5	Gene names	ZNF337
Domain Architecture
Description	Zinc finger protein 337.

ZN493_HUMAN
θ value	6.88961 (rank : 586)	NC score	0.020249 (rank : 796)
Query Neighborhood Hits	613	Target Neighborhood Hits	754	Shared Neighborhood Hits	75
SwissProt Accessions	Q6ZR52, Q59GM3, Q6ZSF6, Q8N1Z6, Q8N965	Gene names	ZNF493
Domain Architecture	No domain graphic available
Description	Zinc finger protein 493.

ZN564_HUMAN
θ value	6.88961 (rank : 587)	NC score	0.022999 (rank : 756)
Query Neighborhood Hits	613	Target Neighborhood Hits	746	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TBZ8	Gene names	ZNF564
Domain Architecture	No domain graphic available
Description	Zinc finger protein 564.

ZN595_HUMAN
θ value	6.88961 (rank : 588)	NC score	0.022684 (rank : 760)
Query Neighborhood Hits	613	Target Neighborhood Hits	798	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IYB9	Gene names	ZNF595
Domain Architecture	No domain graphic available
Description	Zinc finger protein 595.

ANR10_MOUSE
θ value	8.99809 (rank : 589)	NC score	0.015079 (rank : 816)
Query Neighborhood Hits	613	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ATS2_HUMAN
θ value	8.99809 (rank : 590)	NC score	0.044415 (rank : 706)
Query Neighborhood Hits	613	Target Neighborhood Hits	179	Shared Neighborhood Hits	65
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

C1R_HUMAN
θ value	8.99809 (rank : 591)	NC score	0.069638 (rank : 595)
Query Neighborhood Hits	613	Target Neighborhood Hits	364	Shared Neighborhood Hits	128
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

CILP1_HUMAN
θ value	8.99809 (rank : 592)	NC score	0.041989 (rank : 709)
Query Neighborhood Hits	613	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CRIS3_HUMAN
θ value	8.99809 (rank : 593)	NC score	0.007501 (rank : 830)
Query Neighborhood Hits	613	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	P54108, Q15512, Q5JW83, Q9H108	Gene names	CRISP3
Domain Architecture
Description	Cysteine-rich secretory protein 3 precursor (CRISP-3) (SGP28 protein).

CTRO_MOUSE
θ value	8.99809 (rank : 594)	NC score	0.003858 (rank : 840)
Query Neighborhood Hits	613	Target Neighborhood Hits	2344	Shared Neighborhood Hits	64
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

EPHA4_MOUSE
θ value	8.99809 (rank : 595)	NC score	0.050901 (rank : 690)
Query Neighborhood Hits	613	Target Neighborhood Hits	982	Shared Neighborhood Hits	83
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EZH1_MOUSE
θ value	8.99809 (rank : 596)	NC score	0.032967 (rank : 720)
Query Neighborhood Hits	613	Target Neighborhood Hits	126	Shared Neighborhood Hits	48
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

GAS6_MOUSE
θ value	8.99809 (rank : 597)	NC score	0.364506 (rank : 153)
Query Neighborhood Hits	613	Target Neighborhood Hits	343	Shared Neighborhood Hits	236
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GP158_HUMAN
θ value	8.99809 (rank : 598)	NC score	0.019247 (rank : 803)
Query Neighborhood Hits	613	Target Neighborhood Hits	221	Shared Neighborhood Hits	19
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

KR102_HUMAN
θ value	8.99809 (rank : 599)	NC score	0.340505 (rank : 172)
Query Neighborhood Hits	613	Target Neighborhood Hits	264	Shared Neighborhood Hits	195
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KRHB1_HUMAN
θ value	8.99809 (rank : 600)	NC score	0.002717 (rank : 845)
Query Neighborhood Hits	613	Target Neighborhood Hits	461	Shared Neighborhood Hits	27
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

LRP6_MOUSE
θ value	8.99809 (rank : 601)	NC score	0.174163 (rank : 333)
Query Neighborhood Hits	613	Target Neighborhood Hits	232	Shared Neighborhood Hits	135
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MYCB2_MOUSE
θ value	8.99809 (rank : 602)	NC score	0.024623 (rank : 739)
Query Neighborhood Hits	613	Target Neighborhood Hits	307	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

SEM5B_MOUSE
θ value	8.99809 (rank : 603)	NC score	0.044541 (rank : 705)
Query Neighborhood Hits	613	Target Neighborhood Hits	190	Shared Neighborhood Hits	67
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

TNR11_MOUSE
θ value	8.99809 (rank : 604)	NC score	0.136301 (rank : 402)
Query Neighborhood Hits	613	Target Neighborhood Hits	121	Shared Neighborhood Hits	95
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

WNT9B_MOUSE
θ value	8.99809 (rank : 605)	NC score	0.001739 (rank : 847)
Query Neighborhood Hits	613	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	O35468, Q8VI90	Gene names	Wnt9b, Wnt14b, Wnt15
Domain Architecture
Description	Protein Wnt-9b precursor (Wnt-15) (Wnt-14b).

ZN195_HUMAN
θ value	8.99809 (rank : 606)	NC score	0.020596 (rank : 793)
Query Neighborhood Hits	613	Target Neighborhood Hits	760	Shared Neighborhood Hits	83
SwissProt Accessions	O14628	Gene names	ZNF195, ZNFP104
Domain Architecture
Description	Zinc finger protein 195.

ZN266_HUMAN
θ value	8.99809 (rank : 607)	NC score	0.021062 (rank : 787)
Query Neighborhood Hits	613	Target Neighborhood Hits	750	Shared Neighborhood Hits	77
SwissProt Accessions	Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9	Gene names	ZNF266, KIAA2007
Domain Architecture	No domain graphic available
Description	Zinc finger protein 266 (Zinc finger protein HZF1).

ZN271_HUMAN
θ value	8.99809 (rank : 608)	NC score	0.021110 (rank : 783)
Query Neighborhood Hits	613	Target Neighborhood Hits	769	Shared Neighborhood Hits	80
SwissProt Accessions	Q14591, Q96T29, Q9BSX2, Q9UN33, Q9Y5B7	Gene names	ZNF271, ZNFEB
Domain Architecture	No domain graphic available
Description	Zinc finger protein 271 (Zinc finger protein HZF7) (Zinc finger protein ZNFphex133) (Epstein-Barr virus-induced zinc finger protein) (ZNF-EB) (CT-ZFP48) (Zinc finger protein dp) (ZNF-dp).

ZN304_HUMAN
θ value	8.99809 (rank : 609)	NC score	0.020248 (rank : 797)
Query Neighborhood Hits	613	Target Neighborhood Hits	756	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HCX3	Gene names	ZNF304
Domain Architecture
Description	Zinc finger protein 304.

ZN383_HUMAN
θ value	8.99809 (rank : 610)	NC score	0.021426 (rank : 778)
Query Neighborhood Hits	613	Target Neighborhood Hits	758	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NA42, Q6X2C7	Gene names	ZNF383
Domain Architecture	No domain graphic available
Description	Zinc finger protein 383.

ZN615_HUMAN
θ value	8.99809 (rank : 611)	NC score	0.023375 (rank : 753)
Query Neighborhood Hits	613	Target Neighborhood Hits	775	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N8J6	Gene names	ZNF615
Domain Architecture	No domain graphic available
Description	Zinc finger protein 615.

ZN679_HUMAN
θ value	8.99809 (rank : 612)	NC score	0.020166 (rank : 799)
Query Neighborhood Hits	613	Target Neighborhood Hits	746	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IYX0	Gene names	ZNF679
Domain Architecture	No domain graphic available
Description	Zinc finger protein 679.

ZN684_HUMAN
θ value	8.99809 (rank : 613)	NC score	0.018802 (rank : 806)
Query Neighborhood Hits	613	Target Neighborhood Hits	731	Shared Neighborhood Hits	73
SwissProt Accessions	Q5T5D7, Q2NKY4	Gene names	ZNF684
Domain Architecture	No domain graphic available
Description	Zinc finger protein 684.

AD26A_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.075281 (rank : 569)
Query Neighborhood Hits	613	Target Neighborhood Hits	165	Shared Neighborhood Hits	114
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA10_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.107478 (rank : 472)
Query Neighborhood Hits	613	Target Neighborhood Hits	189	Shared Neighborhood Hits	132
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.105159 (rank : 479)
Query Neighborhood Hits	613	Target Neighborhood Hits	194	Shared Neighborhood Hits	128
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA17_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.097667 (rank : 506)
Query Neighborhood Hits	613	Target Neighborhood Hits	201	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA18_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.112177 (rank : 465)
Query Neighborhood Hits	613	Target Neighborhood Hits	227	Shared Neighborhood Hits	170
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA21_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.089047 (rank : 531)
Query Neighborhood Hits	613	Target Neighborhood Hits	172	Shared Neighborhood Hits	119
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA23_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.119558 (rank : 444)
Query Neighborhood Hits	613	Target Neighborhood Hits	235	Shared Neighborhood Hits	162
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA25_MOUSE
θ value	θ > 10 (rank : 621)	NC score	0.091645 (rank : 523)
Query Neighborhood Hits	613	Target Neighborhood Hits	213	Shared Neighborhood Hits	146
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA28_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.103297 (rank : 481)
Query Neighborhood Hits	613	Target Neighborhood Hits	244	Shared Neighborhood Hits	172
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA28_MOUSE
θ value	θ > 10 (rank : 623)	NC score	0.099074 (rank : 500)
Query Neighborhood Hits	613	Target Neighborhood Hits	241	Shared Neighborhood Hits	162
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA30_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.092287 (rank : 521)
Query Neighborhood Hits	613	Target Neighborhood Hits	391	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA32_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.095204 (rank : 514)
Query Neighborhood Hits	613	Target Neighborhood Hits	216	Shared Neighborhood Hits	145
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.088086 (rank : 535)
Query Neighborhood Hits	613	Target Neighborhood Hits	219	Shared Neighborhood Hits	149
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADAM2_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.089307 (rank : 530)
Query Neighborhood Hits	613	Target Neighborhood Hits	175	Shared Neighborhood Hits	121
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM7_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.092518 (rank : 520)
Query Neighborhood Hits	613	Target Neighborhood Hits	200	Shared Neighborhood Hits	144
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM9_MOUSE
θ value	θ > 10 (rank : 629)	NC score	0.113325 (rank : 461)
Query Neighborhood Hits	613	Target Neighborhood Hits	325	Shared Neighborhood Hits	193
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADM1A_MOUSE
θ value	θ > 10 (rank : 630)	NC score	0.105175 (rank : 477)
Query Neighborhood Hits	613	Target Neighborhood Hits	230	Shared Neighborhood Hits	167
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

APR3_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.072985 (rank : 579)
Query Neighborhood Hits	613	Target Neighborhood Hits	50	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

APR3_MOUSE
θ value	θ > 10 (rank : 632)	NC score	0.076349 (rank : 561)
Query Neighborhood Hits	613	Target Neighborhood Hits	61	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ASTN_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.097328 (rank : 507)
Query Neighborhood Hits	613	Target Neighborhood Hits	105	Shared Neighborhood Hits	76
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 634)	NC score	0.096444 (rank : 509)
Query Neighborhood Hits	613	Target Neighborhood Hits	98	Shared Neighborhood Hits	73
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATS12_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.051023 (rank : 688)
Query Neighborhood Hits	613	Target Neighborhood Hits	220	Shared Neighborhood Hits	86
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS16_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.053931 (rank : 675)
Query Neighborhood Hits	613	Target Neighborhood Hits	208	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.054069 (rank : 674)
Query Neighborhood Hits	613	Target Neighborhood Hits	179	Shared Neighborhood Hits	82
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS19_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.052855 (rank : 682)
Query Neighborhood Hits	613	Target Neighborhood Hits	188	Shared Neighborhood Hits	61
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS20_MOUSE
θ value	θ > 10 (rank : 639)	NC score	0.063491 (rank : 622)
Query Neighborhood Hits	613	Target Neighborhood Hits	225	Shared Neighborhood Hits	107
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS7_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.050423 (rank : 694)
Query Neighborhood Hits	613	Target Neighborhood Hits	169	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

BAI1_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.064172 (rank : 618)
Query Neighborhood Hits	613	Target Neighborhood Hits	375	Shared Neighborhood Hits	69
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	θ > 10 (rank : 642)	NC score	0.060086 (rank : 640)
Query Neighborhood Hits	613	Target Neighborhood Hits	340	Shared Neighborhood Hits	63
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

C1RA_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.075461 (rank : 567)
Query Neighborhood Hits	613	Target Neighborhood Hits	379	Shared Neighborhood Hits	134
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.074728 (rank : 573)
Query Neighborhood Hits	613	Target Neighborhood Hits	380	Shared Neighborhood Hits	134
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.056739 (rank : 658)
Query Neighborhood Hits	613	Target Neighborhood Hits	359	Shared Neighborhood Hits	123
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CD320_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.121227 (rank : 442)
Query Neighborhood Hits	613	Target Neighborhood Hits	103	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD97_MOUSE
θ value	θ > 10 (rank : 647)	NC score	0.248456 (rank : 274)
Query Neighborhood Hits	613	Target Neighborhood Hits	295	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CFC1_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.191850 (rank : 313)
Query Neighborhood Hits	613	Target Neighborhood Hits	148	Shared Neighborhood Hits	105
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 649)	NC score	0.168650 (rank : 343)
Query Neighborhood Hits	613	Target Neighborhood Hits	125	Shared Neighborhood Hits	92
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CHRD_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.126240 (rank : 429)
Query Neighborhood Hits	613	Target Neighborhood Hits	102	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 651)	NC score	0.122627 (rank : 436)
Query Neighborhood Hits	613	Target Neighborhood Hits	102	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CLC14_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.127333 (rank : 426)
Query Neighborhood Hits	613	Target Neighborhood Hits	143	Shared Neighborhood Hits	95
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 653)	NC score	0.137325 (rank : 401)
Query Neighborhood Hits	613	Target Neighborhood Hits	120	Shared Neighborhood Hits	89
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CNTP1_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.078163 (rank : 557)
Query Neighborhood Hits	613	Target Neighborhood Hits	196	Shared Neighborhood Hits	89
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.075579 (rank : 565)
Query Neighborhood Hits	613	Target Neighborhood Hits	183	Shared Neighborhood Hits	81
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP2_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.095214 (rank : 513)
Query Neighborhood Hits	613	Target Neighborhood Hits	199	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 657)	NC score	0.096391 (rank : 510)
Query Neighborhood Hits	613	Target Neighborhood Hits	194	Shared Neighborhood Hits	100
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.082126 (rank : 548)
Query Neighborhood Hits	613	Target Neighborhood Hits	195	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP4_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.088884 (rank : 532)
Query Neighborhood Hits	613	Target Neighborhood Hits	187	Shared Neighborhood Hits	89
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.090413 (rank : 527)
Query Neighborhood Hits	613	Target Neighborhood Hits	193	Shared Neighborhood Hits	99
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CO7_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.113514 (rank : 460)
Query Neighborhood Hits	613	Target Neighborhood Hits	278	Shared Neighborhood Hits	146
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.082210 (rank : 546)
Query Neighborhood Hits	613	Target Neighborhood Hits	200	Shared Neighborhood Hits	113
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
θ value	θ > 10 (rank : 663)	NC score	0.077563 (rank : 560)
Query Neighborhood Hits	613	Target Neighborhood Hits	182	Shared Neighborhood Hits	93
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.081790 (rank : 550)
Query Neighborhood Hits	613	Target Neighborhood Hits	199	Shared Neighborhood Hits	102
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 665)	NC score	0.101780 (rank : 488)
Query Neighborhood Hits	613	Target Neighborhood Hits	224	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO9_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.074370 (rank : 574)
Query Neighborhood Hits	613	Target Neighborhood Hits	147	Shared Neighborhood Hits	71
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 667)	NC score	0.075801 (rank : 564)
Query Neighborhood Hits	613	Target Neighborhood Hits	153	Shared Neighborhood Hits	79
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

COCA1_HUMAN
θ value	θ > 10 (rank : 668)	NC score	0.055220 (rank : 668)
Query Neighborhood Hits	613	Target Neighborhood Hits	458	Shared Neighborhood Hits	42
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 669)	NC score	0.056743 (rank : 657)
Query Neighborhood Hits	613	Target Neighborhood Hits	467	Shared Neighborhood Hits	41
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COKA1_HUMAN
θ value	θ > 10 (rank : 670)	NC score	0.055882 (rank : 662)
Query Neighborhood Hits	613	Target Neighborhood Hits	403	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

COMP_MOUSE
θ value	θ > 10 (rank : 671)	NC score	0.320053 (rank : 200)
Query Neighborhood Hits	613	Target Neighborhood Hits	290	Shared Neighborhood Hits	222
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CRAC1_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.170149 (rank : 340)
Query Neighborhood Hits	613	Target Neighborhood Hits	111	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 673)	NC score	0.172402 (rank : 335)
Query Neighborhood Hits	613	Target Neighborhood Hits	112	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRDL1_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.087936 (rank : 536)
Query Neighborhood Hits	613	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_MOUSE
θ value	θ > 10 (rank : 675)	NC score	0.087882 (rank : 537)
Query Neighborhood Hits	613	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
θ value	θ > 10 (rank : 676)	NC score	0.097961 (rank : 504)
Query Neighborhood Hits	613	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 677)	NC score	0.101588 (rank : 491)
Query Neighborhood Hits	613	Target Neighborhood Hits	81	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CS1A_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.059225 (rank : 645)
Query Neighborhood Hits	613	Target Neighborhood Hits	360	Shared Neighborhood Hits	121
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 679)	NC score	0.058781 (rank : 649)
Query Neighborhood Hits	613	Target Neighborhood Hits	361	Shared Neighborhood Hits	120
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CSPG2_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.201034 (rank : 304)
Query Neighborhood Hits	613	Target Neighborhood Hits	681	Shared Neighborhood Hits	201
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG4_HUMAN
θ value	θ > 10 (rank : 681)	NC score	0.085015 (rank : 540)
Query Neighborhood Hits	613	Target Neighborhood Hits	112	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 682)	NC score	0.081926 (rank : 549)
Query Neighborhood Hits	613	Target Neighborhood Hits	105	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CTGF_HUMAN
θ value	θ > 10 (rank : 683)	NC score	0.064878 (rank : 614)
Query Neighborhood Hits	613	Target Neighborhood Hits	128	Shared Neighborhood Hits	68
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CTGF_MOUSE
θ value	θ > 10 (rank : 684)	NC score	0.061774 (rank : 631)
Query Neighborhood Hits	613	Target Neighborhood Hits	124	Shared Neighborhood Hits	65
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

CYR61_HUMAN
θ value	θ > 10 (rank : 685)	NC score	0.071205 (rank : 585)
Query Neighborhood Hits	613	Target Neighborhood Hits	159	Shared Neighborhood Hits	84
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 686)	NC score	0.070498 (rank : 590)
Query Neighborhood Hits	613	Target Neighborhood Hits	156	Shared Neighborhood Hits	81
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DKK3_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.060355 (rank : 637)
Query Neighborhood Hits	613	Target Neighborhood Hits	74	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
θ value	θ > 10 (rank : 688)	NC score	0.065390 (rank : 611)
Query Neighborhood Hits	613	Target Neighborhood Hits	83	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

EDIL3_HUMAN
θ value	θ > 10 (rank : 689)	NC score	0.250534 (rank : 272)
Query Neighborhood Hits	613	Target Neighborhood Hits	292	Shared Neighborhood Hits	183
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 690)	NC score	0.258948 (rank : 269)
Query Neighborhood Hits	613	Target Neighborhood Hits	317	Shared Neighborhood Hits	202
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.341973 (rank : 170)
Query Neighborhood Hits	613	Target Neighborhood Hits	325	Shared Neighborhood Hits	230
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 692)	NC score	0.326948 (rank : 188)
Query Neighborhood Hits	613	Target Neighborhood Hits	287	Shared Neighborhood Hits	212
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 693)	NC score	0.304980 (rank : 217)
Query Neighborhood Hits	613	Target Neighborhood Hits	270	Shared Neighborhood Hits	186
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

ELTD1_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.168343 (rank : 345)
Query Neighborhood Hits	613	Target Neighborhood Hits	269	Shared Neighborhood Hits	156
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 695)	NC score	0.238964 (rank : 280)
Query Neighborhood Hits	613	Target Neighborhood Hits	288	Shared Neighborhood Hits	169
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR3_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.131997 (rank : 415)
Query Neighborhood Hits	613	Target Neighborhood Hits	245	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 697)	NC score	0.094735 (rank : 515)
Query Neighborhood Hits	613	Target Neighborhood Hits	191	Shared Neighborhood Hits	102
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

EPHA3_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.055159 (rank : 669)
Query Neighborhood Hits	613	Target Neighborhood Hits	1005	Shared Neighborhood Hits	97
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHA3_MOUSE
θ value	θ > 10 (rank : 699)	NC score	0.055410 (rank : 666)
Query Neighborhood Hits	613	Target Neighborhood Hits	1009	Shared Neighborhood Hits	97
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHA5_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.050694 (rank : 691)
Query Neighborhood Hits	613	Target Neighborhood Hits	1009	Shared Neighborhood Hits	75
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHA6_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.054898 (rank : 670)
Query Neighborhood Hits	613	Target Neighborhood Hits	959	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA6_MOUSE
θ value	θ > 10 (rank : 702)	NC score	0.052918 (rank : 681)
Query Neighborhood Hits	613	Target Neighborhood Hits	946	Shared Neighborhood Hits	78
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB4_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.073228 (rank : 578)
Query Neighborhood Hits	613	Target Neighborhood Hits	1056	Shared Neighborhood Hits	158
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHB4_MOUSE
θ value	θ > 10 (rank : 704)	NC score	0.062032 (rank : 629)
Query Neighborhood Hits	613	Target Neighborhood Hits	1013	Shared Neighborhood Hits	123
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHB6_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.066072 (rank : 609)
Query Neighborhood Hits	613	Target Neighborhood Hits	912	Shared Neighborhood Hits	105
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHB6_MOUSE
θ value	θ > 10 (rank : 706)	NC score	0.061557 (rank : 633)
Query Neighborhood Hits	613	Target Neighborhood Hits	906	Shared Neighborhood Hits	88
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EREG_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.067547 (rank : 599)
Query Neighborhood Hits	613	Target Neighborhood Hits	73	Shared Neighborhood Hits	47
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ESM1_HUMAN
θ value	θ > 10 (rank : 708)	NC score	0.155022 (rank : 364)
Query Neighborhood Hits	613	Target Neighborhood Hits	110	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA10_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.122307 (rank : 437)
Query Neighborhood Hits	613	Target Neighborhood Hits	431	Shared Neighborhood Hits	195
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA12_HUMAN
θ value	θ > 10 (rank : 710)	NC score	0.093355 (rank : 518)
Query Neighborhood Hits	613	Target Neighborhood Hits	425	Shared Neighborhood Hits	164
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.105160 (rank : 478)
Query Neighborhood Hits	613	Target Neighborhood Hits	404	Shared Neighborhood Hits	179
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 712)	NC score	0.082133 (rank : 547)
Query Neighborhood Hits	613	Target Neighborhood Hits	374	Shared Neighborhood Hits	155
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.114094 (rank : 457)
Query Neighborhood Hits	613	Target Neighborhood Hits	421	Shared Neighborhood Hits	181
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FAT2_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.102263 (rank : 485)
Query Neighborhood Hits	613	Target Neighborhood Hits	507	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FATH_HUMAN
θ value	θ > 10 (rank : 715)	NC score	0.187563 (rank : 320)
Query Neighborhood Hits	613	Target Neighborhood Hits	570	Shared Neighborhood Hits	237
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FINC_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.062775 (rank : 624)
Query Neighborhood Hits	613	Target Neighborhood Hits	302	Shared Neighborhood Hits	61
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 717)	NC score	0.066666 (rank : 605)
Query Neighborhood Hits	613	Target Neighborhood Hits	309	Shared Neighborhood Hits	66
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FREM1_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.072850 (rank : 580)
Query Neighborhood Hits	613	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM1_MOUSE
θ value	θ > 10 (rank : 719)	NC score	0.070526 (rank : 589)
Query Neighborhood Hits	613	Target Neighborhood Hits	163	Shared Neighborhood Hits	11
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM2_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.090632 (rank : 526)
Query Neighborhood Hits	613	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FREM2_MOUSE
θ value	θ > 10 (rank : 721)	NC score	0.091732 (rank : 522)
Query Neighborhood Hits	613	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

FREM3_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.079634 (rank : 553)
Query Neighborhood Hits	613	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

FREM3_MOUSE
θ value	θ > 10 (rank : 723)	NC score	0.079506 (rank : 554)
Query Neighborhood Hits	613	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

FSTL3_HUMAN
θ value	θ > 10 (rank : 724)	NC score	0.125200 (rank : 431)
Query Neighborhood Hits	613	Target Neighborhood Hits	162	Shared Neighborhood Hits	102
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 725)	NC score	0.119588 (rank : 443)
Query Neighborhood Hits	613	Target Neighborhood Hits	152	Shared Neighborhood Hits	98
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

GAS6_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.366883 (rank : 150)
Query Neighborhood Hits	613	Target Neighborhood Hits	348	Shared Neighborhood Hits	241
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

HABP2_HUMAN
θ value	θ > 10 (rank : 727)	NC score	0.139295 (rank : 397)
Query Neighborhood Hits	613	Target Neighborhood Hits	431	Shared Neighborhood Hits	194
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 728)	NC score	0.135893 (rank : 405)
Query Neighborhood Hits	613	Target Neighborhood Hits	445	Shared Neighborhood Hits	197
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HGFA_HUMAN
θ value	θ > 10 (rank : 729)	NC score	0.103197 (rank : 483)
Query Neighborhood Hits	613	Target Neighborhood Hits	436	Shared Neighborhood Hits	170
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
θ value	θ > 10 (rank : 730)	NC score	0.103232 (rank : 482)
Query Neighborhood Hits	613	Target Neighborhood Hits	419	Shared Neighborhood Hits	172
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HHIP_HUMAN
θ value	θ > 10 (rank : 731)	NC score	0.295543 (rank : 234)
Query Neighborhood Hits	613	Target Neighborhood Hits	249	Shared Neighborhood Hits	202
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 732)	NC score	0.278283 (rank : 250)
Query Neighborhood Hits	613	Target Neighborhood Hits	219	Shared Neighborhood Hits	170
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

IDD_HUMAN
θ value	θ > 10 (rank : 733)	NC score	0.060047 (rank : 641)
Query Neighborhood Hits	613	Target Neighborhood Hits	127	Shared Neighborhood Hits	45
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

IDD_MOUSE
θ value	θ > 10 (rank : 734)	NC score	0.055516 (rank : 663)
Query Neighborhood Hits	613	Target Neighborhood Hits	151	Shared Neighborhood Hits	45
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

KR111_HUMAN
θ value	θ > 10 (rank : 735)	NC score	0.099750 (rank : 497)
Query Neighborhood Hits	613	Target Neighborhood Hits	90	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

KR122_HUMAN
θ value	θ > 10 (rank : 736)	NC score	0.122012 (rank : 439)
Query Neighborhood Hits	613	Target Neighborhood Hits	97	Shared Neighborhood Hits	66
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KR123_HUMAN
θ value	θ > 10 (rank : 737)	NC score	0.098210 (rank : 503)
Query Neighborhood Hits	613	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

KR124_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.126541 (rank : 428)
Query Neighborhood Hits	613	Target Neighborhood Hits	124	Shared Neighborhood Hits	89
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR133_HUMAN
θ value	θ > 10 (rank : 739)	NC score	0.063912 (rank : 619)
Query Neighborhood Hits	613	Target Neighborhood Hits	66	Shared Neighborhood Hits	48
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

KR134_HUMAN
θ value	θ > 10 (rank : 740)	NC score	0.066778 (rank : 604)
Query Neighborhood Hits	613	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

KR241_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.081321 (rank : 552)
Query Neighborhood Hits	613	Target Neighborhood Hits	71	Shared Neighborhood Hits	52
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

KR261_HUMAN
θ value	θ > 10 (rank : 742)	NC score	0.076045 (rank : 562)
Query Neighborhood Hits	613	Target Neighborhood Hits	65	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

KR410_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.234413 (rank : 283)
Query Neighborhood Hits	613	Target Neighborhood Hits	156	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR413_HUMAN
θ value	θ > 10 (rank : 744)	NC score	0.159813 (rank : 358)
Query Neighborhood Hits	613	Target Neighborhood Hits	112	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR414_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.274590 (rank : 254)
Query Neighborhood Hits	613	Target Neighborhood Hits	199	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA13_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.286030 (rank : 242)
Query Neighborhood Hits	613	Target Neighborhood Hits	144	Shared Neighborhood Hits	115
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA24_HUMAN
θ value	θ > 10 (rank : 747)	NC score	0.176805 (rank : 328)
Query Neighborhood Hits	613	Target Neighborhood Hits	192	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA44_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.275917 (rank : 251)
Query Neighborhood Hits	613	Target Neighborhood Hits	162	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA63_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.056232 (rank : 661)
Query Neighborhood Hits	613	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q3LI67	Gene names	KRTAP6-3, KAP6.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 6-3.

LCE1A_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.196053 (rank : 310)
Query Neighborhood Hits	613	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.244546 (rank : 277)
Query Neighborhood Hits	613	Target Neighborhood Hits	58	Shared Neighborhood Hits	45
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 752)	NC score	0.245497 (rank : 275)
Query Neighborhood Hits	613	Target Neighborhood Hits	65	Shared Neighborhood Hits	50
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.201258 (rank : 302)
Query Neighborhood Hits	613	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.219719 (rank : 293)
Query Neighborhood Hits	613	Target Neighborhood Hits	53	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 755)	NC score	0.223467 (rank : 290)
Query Neighborhood Hits	613	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE3A_HUMAN
θ value	θ > 10 (rank : 756)	NC score	0.183606 (rank : 322)
Query Neighborhood Hits	613	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 757)	NC score	0.082734 (rank : 542)
Query Neighborhood Hits	613	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE3C_HUMAN
θ value	θ > 10 (rank : 758)	NC score	0.058046 (rank : 653)
Query Neighborhood Hits	613	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

LCE4A_HUMAN
θ value	θ > 10 (rank : 759)	NC score	0.141821 (rank : 389)
Query Neighborhood Hits	613	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 760)	NC score	0.149628 (rank : 371)
Query Neighborhood Hits	613	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LORI_MOUSE
θ value	θ > 10 (rank : 761)	NC score	0.100755 (rank : 492)
Query Neighborhood Hits	613	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRP12_HUMAN
θ value	θ > 10 (rank : 762)	NC score	0.104043 (rank : 480)
Query Neighborhood Hits	613	Target Neighborhood Hits	205	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 763)	NC score	0.102582 (rank : 484)
Query Neighborhood Hits	613	Target Neighborhood Hits	180	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP5_HUMAN
θ value	θ > 10 (rank : 764)	NC score	0.166481 (rank : 347)
Query Neighborhood Hits	613	Target Neighborhood Hits	224	Shared Neighborhood Hits	132
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 765)	NC score	0.171218 (rank : 339)
Query Neighborhood Hits	613	Target Neighborhood Hits	236	Shared Neighborhood Hits	138
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LYAM1_HUMAN
θ value	θ > 10 (rank : 766)	NC score	0.146609 (rank : 377)
Query Neighborhood Hits	613	Target Neighborhood Hits	315	Shared Neighborhood Hits	162
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 767)	NC score	0.155067 (rank : 363)
Query Neighborhood Hits	613	Target Neighborhood Hits	332	Shared Neighborhood Hits	165
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MASP2_HUMAN
θ value	θ > 10 (rank : 768)	NC score	0.064742 (rank : 615)
Query Neighborhood Hits	613	Target Neighborhood Hits	364	Shared Neighborhood Hits	122
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MATN1_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.142376 (rank : 387)
Query Neighborhood Hits	613	Target Neighborhood Hits	191	Shared Neighborhood Hits	113
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 770)	NC score	0.142620 (rank : 385)
Query Neighborhood Hits	613	Target Neighborhood Hits	186	Shared Neighborhood Hits	111
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MCSP_MOUSE
θ value	θ > 10 (rank : 771)	NC score	0.133242 (rank : 412)
Query Neighborhood Hits	613	Target Neighborhood Hits	108	Shared Neighborhood Hits	56
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEP1A_HUMAN
θ value	θ > 10 (rank : 772)	NC score	0.075976 (rank : 563)
Query Neighborhood Hits	613	Target Neighborhood Hits	162	Shared Neighborhood Hits	100
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 773)	NC score	0.077808 (rank : 558)
Query Neighborhood Hits	613	Target Neighborhood Hits	166	Shared Neighborhood Hits	99
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MFGM_HUMAN
θ value	θ > 10 (rank : 774)	NC score	0.065044 (rank : 612)
Query Neighborhood Hits	613	Target Neighborhood Hits	150	Shared Neighborhood Hits	82
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
θ value	θ > 10 (rank : 775)	NC score	0.168668 (rank : 342)
Query Neighborhood Hits	613	Target Neighborhood Hits	233	Shared Neighborhood Hits	140
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MFRP_HUMAN
θ value	θ > 10 (rank : 776)	NC score	0.058351 (rank : 652)
Query Neighborhood Hits	613	Target Neighborhood Hits	165	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MKS3_HUMAN
θ value	θ > 10 (rank : 777)	NC score	0.117284 (rank : 450)
Query Neighborhood Hits	613	Target Neighborhood Hits	79	Shared Neighborhood Hits	71
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

MMRN1_HUMAN
θ value	θ > 10 (rank : 778)	NC score	0.082390 (rank : 543)
Query Neighborhood Hits	613	Target Neighborhood Hits	636	Shared Neighborhood Hits	108
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MUC13_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.086105 (rank : 539)
Query Neighborhood Hits	613	Target Neighborhood Hits	164	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MUC13_MOUSE
θ value	θ > 10 (rank : 780)	NC score	0.141696 (rank : 390)
Query Neighborhood Hits	613	Target Neighborhood Hits	447	Shared Neighborhood Hits	148
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

NAGPA_MOUSE
θ value	θ > 10 (rank : 781)	NC score	0.358982 (rank : 157)
Query Neighborhood Hits	613	Target Neighborhood Hits	308	Shared Neighborhood Hits	239
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NOV_HUMAN
θ value	θ > 10 (rank : 782)	NC score	0.068594 (rank : 596)
Query Neighborhood Hits	613	Target Neighborhood Hits	128	Shared Neighborhood Hits	69
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOV_MOUSE
θ value	θ > 10 (rank : 783)	NC score	0.053847 (rank : 677)
Query Neighborhood Hits	613	Target Neighborhood Hits	130	Shared Neighborhood Hits	66
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NRG1_HUMAN
θ value	θ > 10 (rank : 784)	NC score	0.077707 (rank : 559)
Query Neighborhood Hits	613	Target Neighborhood Hits	285	Shared Neighborhood Hits	73
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG2_HUMAN
θ value	θ > 10 (rank : 785)	NC score	0.061588 (rank : 632)
Query Neighborhood Hits	613	Target Neighborhood Hits	419	Shared Neighborhood Hits	75
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 786)	NC score	0.074104 (rank : 576)
Query Neighborhood Hits	613	Target Neighborhood Hits	392	Shared Neighborhood Hits	89
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG4_HUMAN
θ value	θ > 10 (rank : 787)	NC score	0.082322 (rank : 545)
Query Neighborhood Hits	613	Target Neighborhood Hits	85	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 788)	NC score	0.072682 (rank : 581)
Query Neighborhood Hits	613	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRX1A_HUMAN
θ value	θ > 10 (rank : 789)	NC score	0.113637 (rank : 459)
Query Neighborhood Hits	613	Target Neighborhood Hits	170	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 790)	NC score	0.112563 (rank : 463)
Query Neighborhood Hits	613	Target Neighborhood Hits	164	Shared Neighborhood Hits	92
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX2A_HUMAN
θ value	θ > 10 (rank : 791)	NC score	0.101691 (rank : 490)
Query Neighborhood Hits	613	Target Neighborhood Hits	614	Shared Neighborhood Hits	100
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 792)	NC score	0.106576 (rank : 474)
Query Neighborhood Hits	613	Target Neighborhood Hits	164	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

NTNG1_HUMAN
θ value	θ > 10 (rank : 793)	NC score	0.336314 (rank : 181)
Query Neighborhood Hits	613	Target Neighborhood Hits	247	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 794)	NC score	0.332252 (rank : 183)
Query Neighborhood Hits	613	Target Neighborhood Hits	246	Shared Neighborhood Hits	186
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

ODFP_MOUSE
θ value	θ > 10 (rank : 795)	NC score	0.060012 (rank : 642)
Query Neighborhood Hits	613	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PERT_HUMAN
θ value	θ > 10 (rank : 796)	NC score	0.154258 (rank : 366)
Query Neighborhood Hits	613	Target Neighborhood Hits	221	Shared Neighborhood Hits	139
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 797)	NC score	0.144790 (rank : 382)
Query Neighborhood Hits	613	Target Neighborhood Hits	221	Shared Neighborhood Hits	132
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGCB_HUMAN
θ value	θ > 10 (rank : 798)	NC score	0.091186 (rank : 524)
Query Neighborhood Hits	613	Target Neighborhood Hits	478	Shared Neighborhood Hits	137
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 799)	NC score	0.097732 (rank : 505)
Query Neighborhood Hits	613	Target Neighborhood Hits	459	Shared Neighborhood Hits	140
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PGH1_MOUSE
θ value	θ > 10 (rank : 800)	NC score	0.056288 (rank : 660)
Query Neighborhood Hits	613	Target Neighborhood Hits	100	Shared Neighborhood Hits	56
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_HUMAN
θ value	θ > 10 (rank : 801)	NC score	0.060421 (rank : 636)
Query Neighborhood Hits	613	Target Neighborhood Hits	103	Shared Neighborhood Hits	59
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
θ value	θ > 10 (rank : 802)	NC score	0.064515 (rank : 617)
Query Neighborhood Hits	613	Target Neighborhood Hits	113	Shared Neighborhood Hits	67
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PHXR5_MOUSE
θ value	θ > 10 (rank : 803)	NC score	0.117122 (rank : 451)
Query Neighborhood Hits	613	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PROC_HUMAN
θ value	θ > 10 (rank : 804)	NC score	0.106553 (rank : 475)
Query Neighborhood Hits	613	Target Neighborhood Hits	406	Shared Neighborhood Hits	192
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROP_HUMAN
θ value	θ > 10 (rank : 805)	NC score	0.078597 (rank : 555)
Query Neighborhood Hits	613	Target Neighborhood Hits	126	Shared Neighborhood Hits	56
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROZ_HUMAN
θ value	θ > 10 (rank : 806)	NC score	0.228889 (rank : 286)
Query Neighborhood Hits	613	Target Neighborhood Hits	422	Shared Neighborhood Hits	199
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 807)	NC score	0.231853 (rank : 284)
Query Neighborhood Hits	613	Target Neighborhood Hits	410	Shared Neighborhood Hits	191
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

RECK_HUMAN
θ value	θ > 10 (rank : 808)	NC score	0.162621 (rank : 354)
Query Neighborhood Hits	613	Target Neighborhood Hits	189	Shared Neighborhood Hits	114
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 809)	NC score	0.146014 (rank : 379)
Query Neighborhood Hits	613	Target Neighborhood Hits	158	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RELN_HUMAN
θ value	θ > 10 (rank : 810)	NC score	0.119077 (rank : 446)
Query Neighborhood Hits	613	Target Neighborhood Hits	233	Shared Neighborhood Hits	148
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	θ > 10 (rank : 811)	NC score	0.122977 (rank : 435)
Query Neighborhood Hits	613	Target Neighborhood Hits	235	Shared Neighborhood Hits	149
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

SHBG_HUMAN
θ value	θ > 10 (rank : 812)	NC score	0.066623 (rank : 607)
Query Neighborhood Hits	613	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SHBG_MOUSE
θ value	θ > 10 (rank : 813)	NC score	0.061866 (rank : 630)
Query Neighborhood Hits	613	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SMDF_HUMAN
θ value	θ > 10 (rank : 814)	NC score	0.078409 (rank : 556)
Query Neighborhood Hits	613	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SPIT1_HUMAN
θ value	θ > 10 (rank : 815)	NC score	0.050087 (rank : 696)
Query Neighborhood Hits	613	Target Neighborhood Hits	100	Shared Neighborhood Hits	42
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPON1_HUMAN
θ value	θ > 10 (rank : 816)	NC score	0.069950 (rank : 592)
Query Neighborhood Hits	613	Target Neighborhood Hits	117	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	θ > 10 (rank : 817)	NC score	0.072532 (rank : 582)
Query Neighborhood Hits	613	Target Neighborhood Hits	123	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPR2B_MOUSE
θ value	θ > 10 (rank : 818)	NC score	0.070760 (rank : 587)
Query Neighborhood Hits	613	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2D_MOUSE
θ value	θ > 10 (rank : 819)	NC score	0.094170 (rank : 516)
Query Neighborhood Hits	613	Target Neighborhood Hits	61	Shared Neighborhood Hits	23
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_HUMAN
θ value	θ > 10 (rank : 820)	NC score	0.054695 (rank : 672)
Query Neighborhood Hits	613	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2E_MOUSE
θ value	θ > 10 (rank : 821)	NC score	0.066572 (rank : 608)
Query Neighborhood Hits	613	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2F_HUMAN
θ value	θ > 10 (rank : 822)	NC score	0.075055 (rank : 571)
Query Neighborhood Hits	613	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2F_MOUSE
θ value	θ > 10 (rank : 823)	NC score	0.051371 (rank : 686)
Query Neighborhood Hits	613	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SPR2G_MOUSE
θ value	θ > 10 (rank : 824)	NC score	0.092684 (rank : 519)
Query Neighborhood Hits	613	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 825)	NC score	0.082337 (rank : 544)
Query Neighborhood Hits	613	Target Neighborhood Hits	82	Shared Neighborhood Hits	28
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2I_MOUSE
θ value	θ > 10 (rank : 826)	NC score	0.066661 (rank : 606)
Query Neighborhood Hits	613	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

ST14_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.089768 (rank : 528)
Query Neighborhood Hits	613	Target Neighborhood Hits	409	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 828)	NC score	0.088868 (rank : 533)
Query Neighborhood Hits	613	Target Neighborhood Hits	419	Shared Neighborhood Hits	171
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

SUSD1_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.325618 (rank : 190)
Query Neighborhood Hits	613	Target Neighborhood Hits	285	Shared Neighborhood Hits	182
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_HUMAN
θ value	θ > 10 (rank : 830)	NC score	0.145722 (rank : 380)
Query Neighborhood Hits	613	Target Neighborhood Hits	132	Shared Neighborhood Hits	91
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 831)	NC score	0.177059 (rank : 327)
Query Neighborhood Hits	613	Target Neighborhood Hits	146	Shared Neighborhood Hits	104
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 832)	NC score	0.145537 (rank : 381)
Query Neighborhood Hits	613	Target Neighborhood Hits	131	Shared Neighborhood Hits	88
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TENN_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.212694 (rank : 295)
Query Neighborhood Hits	613	Target Neighborhood Hits	453	Shared Neighborhood Hits	235
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TLL2_HUMAN
θ value	θ > 10 (rank : 834)	NC score	0.137520 (rank : 400)
Query Neighborhood Hits	613	Target Neighborhood Hits	241	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TMPS6_HUMAN
θ value	θ > 10 (rank : 835)	NC score	0.058896 (rank : 647)
Query Neighborhood Hits	613	Target Neighborhood Hits	338	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 836)	NC score	0.053908 (rank : 676)
Query Neighborhood Hits	613	Target Neighborhood Hits	341	Shared Neighborhood Hits	115
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TNR18_HUMAN
θ value	θ > 10 (rank : 837)	NC score	0.073494 (rank : 577)
Query Neighborhood Hits	613	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR4_HUMAN
θ value	θ > 10 (rank : 838)	NC score	0.172128 (rank : 336)
Query Neighborhood Hits	613	Target Neighborhood Hits	152	Shared Neighborhood Hits	106
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR8_MOUSE
θ value	θ > 10 (rank : 839)	NC score	0.134648 (rank : 408)
Query Neighborhood Hits	613	Target Neighborhood Hits	208	Shared Neighborhood Hits	109
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TR19L_HUMAN
θ value	θ > 10 (rank : 840)	NC score	0.065036 (rank : 613)
Query Neighborhood Hits	613	Target Neighborhood Hits	99	Shared Neighborhood Hits	56
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TSP3_HUMAN
θ value	θ > 10 (rank : 841)	NC score	0.282674 (rank : 245)
Query Neighborhood Hits	613	Target Neighborhood Hits	250	Shared Neighborhood Hits	180
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 842)	NC score	0.287154 (rank : 239)
Query Neighborhood Hits	613	Target Neighborhood Hits	247	Shared Neighborhood Hits	189
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 843)	NC score	0.308581 (rank : 215)
Query Neighborhood Hits	613	Target Neighborhood Hits	277	Shared Neighborhood Hits	204
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROL1_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.139590 (rank : 394)
Query Neighborhood Hits	613	Target Neighborhood Hits	213	Shared Neighborhood Hits	116
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 845)	NC score	0.146604 (rank : 378)
Query Neighborhood Hits	613	Target Neighborhood Hits	235	Shared Neighborhood Hits	122
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

WFDC2_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.053344 (rank : 679)
Query Neighborhood Hits	613	Target Neighborhood Hits	73	Shared Neighborhood Hits	47
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

WISP1_MOUSE
θ value	θ > 10 (rank : 847)	NC score	0.050588 (rank : 692)
Query Neighborhood Hits	613	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WISP2_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.069736 (rank : 594)
Query Neighborhood Hits	613	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
θ value	θ > 10 (rank : 849)	NC score	0.066914 (rank : 603)
Query Neighborhood Hits	613	Target Neighborhood Hits	129	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

Hits sorted by NC score

PCSK5_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	613	Target Neighborhood Hits	613	Shared Neighborhood Hits	613
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK5_HUMAN
NC score	0.907094 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	613	Target Neighborhood Hits	291	Shared Neighborhood Hits	270
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK6_HUMAN
NC score	0.883122 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	613	Target Neighborhood Hits	298	Shared Neighborhood Hits	217
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

FURIN_MOUSE
NC score	0.745217 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	613	Target Neighborhood Hits	49	Shared Neighborhood Hits	42
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

FURIN_HUMAN
NC score	0.743338 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	613	Target Neighborhood Hits	52	Shared Neighborhood Hits	43
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

PCSK4_HUMAN
NC score	0.731285 (rank : 6)	θ value	2.17943e-171 (rank : 6)
Query Neighborhood Hits	613	Target Neighborhood Hits	32	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

PCSK4_MOUSE
NC score	0.714243 (rank : 7)	θ value	5.21151e-157 (rank : 8)
Query Neighborhood Hits	613	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

NEC1_MOUSE
NC score	0.711170 (rank : 8)	θ value	9.82853e-156 (rank : 9)
Query Neighborhood Hits	613	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	P63239, P21662, P22546	Gene names	Pcsk1, Att-1, Nec-1, Nec1
Domain Architecture	No domain graphic available
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1) (PC3) (Furin homolog) (Propeptide-processing protease).

NEC1_HUMAN
NC score	0.711155 (rank : 9)	θ value	1.79118e-157 (rank : 7)
Query Neighborhood Hits	613	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P29120, P78478, Q92532	Gene names	PCSK1, NEC1
Domain Architecture
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1).

NEC2_MOUSE
NC score	0.708210 (rank : 10)	θ value	2.51683e-135 (rank : 10)
Query Neighborhood Hits	613	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	P21661, Q80WU1	Gene names	Pcsk2, Nec-2, Nec2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

NEC2_HUMAN
NC score	0.707977 (rank : 11)	θ value	1.24909e-134 (rank : 11)
Query Neighborhood Hits	613	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	P16519, Q14927, Q9NQG3, Q9NUG1, Q9UJC6	Gene names	PCSK2, NEC2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

PCSK7_MOUSE
NC score	0.702832 (rank : 12)	θ value	5.8157e-124 (rank : 12)
Query Neighborhood Hits	613	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

PCSK7_HUMAN
NC score	0.702830 (rank : 13)	θ value	8.39787e-123 (rank : 13)
Query Neighborhood Hits	613	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

FRAS1_HUMAN
NC score	0.569425 (rank : 14)	θ value	7.66637e-92 (rank : 15)
Query Neighborhood Hits	613	Target Neighborhood Hits	759	Shared Neighborhood Hits	415
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MEGF6_HUMAN
NC score	0.566816 (rank : 15)	θ value	1.33217e-27 (rank : 16)
Query Neighborhood Hits	613	Target Neighborhood Hits	671	Shared Neighborhood Hits	402
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

FRAS1_MOUSE
NC score	0.561484 (rank : 16)	θ value	2.08291e-97 (rank : 14)
Query Neighborhood Hits	613	Target Neighborhood Hits	747	Shared Neighborhood Hits	411
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SREC_HUMAN
NC score	0.558397 (rank : 17)	θ value	4.02038e-16 (rank : 22)
Query Neighborhood Hits	613	Target Neighborhood Hits	645	Shared Neighborhood Hits	364
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

SREC2_MOUSE
NC score	0.552298 (rank : 18)	θ value	3.18553e-13 (rank : 37)
Query Neighborhood Hits	613	Target Neighborhood Hits	605	Shared Neighborhood Hits	348
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC2_HUMAN
NC score	0.546023 (rank : 19)	θ value	2.88119e-14 (rank : 28)
Query Neighborhood Hits	613	Target Neighborhood Hits	645	Shared Neighborhood Hits	347
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

CREL1_HUMAN
NC score	0.530160 (rank : 20)	θ value	3.29651e-10 (rank : 62)
Query Neighborhood Hits	613	Target Neighborhood Hits	441	Shared Neighborhood Hits	284
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
NC score	0.525336 (rank : 21)	θ value	2.52405e-10 (rank : 59)
Query Neighborhood Hits	613	Target Neighborhood Hits	524	Shared Neighborhood Hits	311
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

KRA51_HUMAN
NC score	0.512057 (rank : 22)	θ value	3.41135e-07 (rank : 99)
Query Neighborhood Hits	613	Target Neighborhood Hits	288	Shared Neighborhood Hits	207
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
NC score	0.508859 (rank : 23)	θ value	1.87187e-05 (rank : 134)
Query Neighborhood Hits	613	Target Neighborhood Hits	331	Shared Neighborhood Hits	246
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

MEGF9_HUMAN
NC score	0.495187 (rank : 24)	θ value	6.00763e-12 (rank : 43)
Query Neighborhood Hits	613	Target Neighborhood Hits	557	Shared Neighborhood Hits	298
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

FBN1_HUMAN
NC score	0.495134 (rank : 25)	θ value	1.63225e-17 (rank : 20)
Query Neighborhood Hits	613	Target Neighborhood Hits	557	Shared Neighborhood Hits	353
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
NC score	0.494051 (rank : 26)	θ value	1.29331e-14 (rank : 27)
Query Neighborhood Hits	613	Target Neighborhood Hits	560	Shared Neighborhood Hits	349
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.493866 (rank : 27)	θ value	1.52774e-15 (rank : 23)
Query Neighborhood Hits	613	Target Neighborhood Hits	563	Shared Neighborhood Hits	352
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN3_HUMAN
NC score	0.493541 (rank : 28)	θ value	1.09485e-13 (rank : 32)
Query Neighborhood Hits	613	Target Neighborhood Hits	543	Shared Neighborhood Hits	343
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

MEGF8_HUMAN
NC score	0.493405 (rank : 29)	θ value	7.34386e-10 (rank : 66)
Query Neighborhood Hits	613	Target Neighborhood Hits	528	Shared Neighborhood Hits	324
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

ZAN_MOUSE
NC score	0.491622 (rank : 30)	θ value	4.28545e-26 (rank : 17)
Query Neighborhood Hits	613	Target Neighborhood Hits	808	Shared Neighborhood Hits	388
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

FBN2_MOUSE
NC score	0.490365 (rank : 31)	θ value	2.60593e-15 (rank : 25)
Query Neighborhood Hits	613	Target Neighborhood Hits	549	Shared Neighborhood Hits	357
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

MEGF8_MOUSE
NC score	0.486188 (rank : 32)	θ value	7.34386e-10 (rank : 67)
Query Neighborhood Hits	613	Target Neighborhood Hits	520	Shared Neighborhood Hits	311
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LTBP2_MOUSE
NC score	0.485409 (rank : 33)	θ value	9.56915e-18 (rank : 19)
Query Neighborhood Hits	613	Target Neighborhood Hits	617	Shared Neighborhood Hits	312
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

KRA59_HUMAN
NC score	0.484602 (rank : 34)	θ value	1.69304e-06 (rank : 113)
Query Neighborhood Hits	613	Target Neighborhood Hits	310	Shared Neighborhood Hits	213
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LTBP4_MOUSE
NC score	0.481257 (rank : 35)	θ value	8.97725e-08 (rank : 88)
Query Neighborhood Hits	613	Target Neighborhood Hits	607	Shared Neighborhood Hits	316
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LTBP2_HUMAN
NC score	0.479997 (rank : 36)	θ value	4.44505e-15 (rank : 26)
Query Neighborhood Hits	613	Target Neighborhood Hits	552	Shared Neighborhood Hits	317
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MEGF9_MOUSE
NC score	0.477842 (rank : 37)	θ value	7.09661e-13 (rank : 38)
Query Neighborhood Hits	613	Target Neighborhood Hits	896	Shared Neighborhood Hits	295
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NELL1_HUMAN
NC score	0.476746 (rank : 38)	θ value	9.29e-05 (rank : 154)
Query Neighborhood Hits	613	Target Neighborhood Hits	451	Shared Neighborhood Hits	307
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

JAG1_HUMAN
NC score	0.474256 (rank : 39)	θ value	1.29631e-06 (rank : 111)
Query Neighborhood Hits	613	Target Neighborhood Hits	514	Shared Neighborhood Hits	314
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

KRA58_HUMAN
NC score	0.474179 (rank : 40)	θ value	2.61198e-07 (rank : 96)
Query Neighborhood Hits	613	Target Neighborhood Hits	324	Shared Neighborhood Hits	229
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA54_HUMAN
NC score	0.472112 (rank : 41)	θ value	3.08544e-08 (rank : 84)
Query Neighborhood Hits	613	Target Neighborhood Hits	270	Shared Neighborhood Hits	191
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

JAG1_MOUSE
NC score	0.472033 (rank : 42)	θ value	2.44474e-05 (rank : 138)
Query Neighborhood Hits	613	Target Neighborhood Hits	518	Shared Neighborhood Hits	316
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

KRA55_HUMAN
NC score	0.471409 (rank : 43)	θ value	1.43324e-05 (rank : 129)
Query Neighborhood Hits	613	Target Neighborhood Hits	257	Shared Neighborhood Hits	182
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

NOTC1_MOUSE
NC score	0.470368 (rank : 44)	θ value	5.07402e-19 (rank : 18)
Query Neighborhood Hits	613	Target Neighborhood Hits	916	Shared Neighborhood Hits	344
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NELL2_HUMAN
NC score	0.468495 (rank : 45)	θ value	4.0297e-08 (rank : 86)
Query Neighborhood Hits	613	Target Neighborhood Hits	449	Shared Neighborhood Hits	293
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

JAG2_HUMAN
NC score	0.467891 (rank : 46)	θ value	1.99992e-07 (rank : 95)
Query Neighborhood Hits	613	Target Neighborhood Hits	491	Shared Neighborhood Hits	302
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NELL2_MOUSE
NC score	0.467197 (rank : 47)	θ value	6.21693e-09 (rank : 74)
Query Neighborhood Hits	613	Target Neighborhood Hits	436	Shared Neighborhood Hits	290
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

LAMA5_MOUSE
NC score	0.465297 (rank : 48)	θ value	6.64225e-11 (rank : 52)
Query Neighborhood Hits	613	Target Neighborhood Hits	828	Shared Neighborhood Hits	369
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

JAG2_MOUSE
NC score	0.464529 (rank : 49)	θ value	1.53129e-07 (rank : 93)
Query Neighborhood Hits	613	Target Neighborhood Hits	504	Shared Neighborhood Hits	310
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

SCUB3_MOUSE
NC score	0.461335 (rank : 50)	θ value	3.41135e-07 (rank : 100)
Query Neighborhood Hits	613	Target Neighborhood Hits	442	Shared Neighborhood Hits	301
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.457480 (rank : 51)	θ value	6.21693e-09 (rank : 75)
Query Neighborhood Hits	613	Target Neighborhood Hits	428	Shared Neighborhood Hits	293
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

NOTC1_HUMAN
NC score	0.457080 (rank : 52)	θ value	1.38178e-16 (rank : 21)
Query Neighborhood Hits	613	Target Neighborhood Hits	906	Shared Neighborhood Hits	346
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LAMA5_HUMAN
NC score	0.457014 (rank : 53)	θ value	2.43908e-13 (rank : 36)
Query Neighborhood Hits	613	Target Neighborhood Hits	976	Shared Neighborhood Hits	366
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LTB1L_HUMAN
NC score	0.455896 (rank : 54)	θ value	2.52405e-10 (rank : 60)
Query Neighborhood Hits	613	Target Neighborhood Hits	553	Shared Neighborhood Hits	301
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.455113 (rank : 55)	θ value	2.52405e-10 (rank : 61)
Query Neighborhood Hits	613	Target Neighborhood Hits	502	Shared Neighborhood Hits	287
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_MOUSE
NC score	0.453932 (rank : 56)	θ value	1.17247e-07 (rank : 90)
Query Neighborhood Hits	613	Target Neighborhood Hits	475	Shared Neighborhood Hits	300
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

STAB1_HUMAN
NC score	0.453783 (rank : 57)	θ value	0.000270298 (rank : 167)
Query Neighborhood Hits	613	Target Neighborhood Hits	546	Shared Neighborhood Hits	334
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
NC score	0.453182 (rank : 58)	θ value	3.77169e-06 (rank : 123)
Query Neighborhood Hits	613	Target Neighborhood Hits	566	Shared Neighborhood Hits	341
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

NOTC3_HUMAN
NC score	0.452026 (rank : 59)	θ value	1.52774e-15 (rank : 24)
Query Neighborhood Hits	613	Target Neighborhood Hits	1062	Shared Neighborhood Hits	345
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LTBP3_HUMAN
NC score	0.451978 (rank : 60)	θ value	7.59969e-07 (rank : 108)
Query Neighborhood Hits	613	Target Neighborhood Hits	502	Shared Neighborhood Hits	300
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTB1S_MOUSE
NC score	0.451239 (rank : 61)	θ value	2.88788e-06 (rank : 120)
Query Neighborhood Hits	613	Target Neighborhood Hits	479	Shared Neighborhood Hits	284
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

STAB2_MOUSE
NC score	0.451059 (rank : 62)	θ value	0.000270298 (rank : 168)
Query Neighborhood Hits	613	Target Neighborhood Hits	528	Shared Neighborhood Hits	337
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

STAB2_HUMAN
NC score	0.450927 (rank : 63)	θ value	0.000121331 (rank : 157)
Query Neighborhood Hits	613	Target Neighborhood Hits	534	Shared Neighborhood Hits	336
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

LTB1L_MOUSE
NC score	0.450567 (rank : 64)	θ value	2.88788e-06 (rank : 119)
Query Neighborhood Hits	613	Target Neighborhood Hits	514	Shared Neighborhood Hits	299
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NOTC3_MOUSE
NC score	0.449894 (rank : 65)	θ value	4.91457e-14 (rank : 30)
Query Neighborhood Hits	613	Target Neighborhood Hits	975	Shared Neighborhood Hits	347
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LAMB2_HUMAN
NC score	0.448994 (rank : 66)	θ value	1.133e-10 (rank : 55)
Query Neighborhood Hits	613	Target Neighborhood Hits	692	Shared Neighborhood Hits	317
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

DLL4_MOUSE
NC score	0.446295 (rank : 67)	θ value	5.44631e-05 (rank : 145)
Query Neighborhood Hits	613	Target Neighborhood Hits	440	Shared Neighborhood Hits	294
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL1_MOUSE
NC score	0.446263 (rank : 68)	θ value	0.000270298 (rank : 164)
Query Neighborhood Hits	613	Target Neighborhood Hits	456	Shared Neighborhood Hits	306
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

LAMA1_MOUSE
NC score	0.445897 (rank : 69)	θ value	3.76295e-14 (rank : 29)
Query Neighborhood Hits	613	Target Neighborhood Hits	838	Shared Neighborhood Hits	347
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

FBLN2_HUMAN
NC score	0.445634 (rank : 70)	θ value	6.64225e-11 (rank : 50)
Query Neighborhood Hits	613	Target Neighborhood Hits	392	Shared Neighborhood Hits	253
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LAMA1_HUMAN
NC score	0.443816 (rank : 71)	θ value	1.09485e-13 (rank : 33)
Query Neighborhood Hits	613	Target Neighborhood Hits	804	Shared Neighborhood Hits	351
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NOTC2_MOUSE
NC score	0.443727 (rank : 72)	θ value	6.41864e-14 (rank : 31)
Query Neighborhood Hits	613	Target Neighborhood Hits	1069	Shared Neighborhood Hits	340
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

FBLN2_MOUSE
NC score	0.442639 (rank : 73)	θ value	1.99992e-07 (rank : 94)
Query Neighborhood Hits	613	Target Neighborhood Hits	505	Shared Neighborhood Hits	263
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

KR106_HUMAN
NC score	0.442464 (rank : 74)	θ value	1.09739e-05 (rank : 128)
Query Neighborhood Hits	613	Target Neighborhood Hits	347	Shared Neighborhood Hits	257
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
NC score	0.442440 (rank : 75)	θ value	2.88788e-06 (rank : 118)
Query Neighborhood Hits	613	Target Neighborhood Hits	330	Shared Neighborhood Hits	238
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

NOTC2_HUMAN
NC score	0.442145 (rank : 76)	θ value	1.42992e-13 (rank : 35)
Query Neighborhood Hits	613	Target Neighborhood Hits	1113	Shared Neighborhood Hits	352
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

LAMC3_HUMAN
NC score	0.441985 (rank : 77)	θ value	1.42992e-13 (rank : 34)
Query Neighborhood Hits	613	Target Neighborhood Hits	588	Shared Neighborhood Hits	325
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMB2_MOUSE
NC score	0.441845 (rank : 78)	θ value	5.08577e-11 (rank : 49)
Query Neighborhood Hits	613	Target Neighborhood Hits	722	Shared Neighborhood Hits	311
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

NOTC4_HUMAN
NC score	0.441606 (rank : 79)	θ value	1.2105e-12 (rank : 39)
Query Neighborhood Hits	613	Target Neighborhood Hits	905	Shared Neighborhood Hits	347
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

DLL4_HUMAN
NC score	0.439908 (rank : 80)	θ value	0.00228821 (rank : 204)
Query Neighborhood Hits	613	Target Neighborhood Hits	435	Shared Neighborhood Hits	286
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL1_HUMAN
NC score	0.439617 (rank : 81)	θ value	0.00175202 (rank : 199)
Query Neighborhood Hits	613	Target Neighborhood Hits	455	Shared Neighborhood Hits	303
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

LAMC3_MOUSE
NC score	0.437580 (rank : 82)	θ value	1.25267e-09 (rank : 69)
Query Neighborhood Hits	613	Target Neighborhood Hits	624	Shared Neighborhood Hits	313
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

KR104_HUMAN
NC score	0.437359 (rank : 83)	θ value	9.29e-05 (rank : 153)
Query Neighborhood Hits	613	Target Neighborhood Hits	313	Shared Neighborhood Hits	222
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

CRIM1_HUMAN
NC score	0.436515 (rank : 84)	θ value	3.64472e-09 (rank : 72)
Query Neighborhood Hits	613	Target Neighborhood Hits	362	Shared Neighborhood Hits	244
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

NOTC4_MOUSE
NC score	0.436191 (rank : 85)	θ value	3.89403e-11 (rank : 48)
Query Neighborhood Hits	613	Target Neighborhood Hits	872	Shared Neighborhood Hits	338
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

DNER_HUMAN
NC score	0.435265 (rank : 86)	θ value	0.00035302 (rank : 173)
Query Neighborhood Hits	613	Target Neighborhood Hits	460	Shared Neighborhood Hits	276
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

KRA57_HUMAN
NC score	0.434351 (rank : 87)	θ value	0.0148317 (rank : 247)
Query Neighborhood Hits	613	Target Neighborhood Hits	269	Shared Neighborhood Hits	194
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

FBLN1_MOUSE
NC score	0.433102 (rank : 88)	θ value	5.81887e-07 (rank : 104)
Query Neighborhood Hits	613	Target Neighborhood Hits	329	Shared Neighborhood Hits	251
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

CRUM1_HUMAN
NC score	0.432547 (rank : 89)	θ value	0.000121331 (rank : 155)
Query Neighborhood Hits	613	Target Neighborhood Hits	457	Shared Neighborhood Hits	284
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
NC score	0.432274 (rank : 90)	θ value	0.000602161 (rank : 180)
Query Neighborhood Hits	613	Target Neighborhood Hits	444	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

WIF1_MOUSE
NC score	0.430220 (rank : 91)	θ value	0.00665767 (rank : 230)
Query Neighborhood Hits	613	Target Neighborhood Hits	393	Shared Neighborhood Hits	284
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

KRA52_HUMAN
NC score	0.429840 (rank : 92)	θ value	0.00102713 (rank : 190)
Query Neighborhood Hits	613	Target Neighborhood Hits	236	Shared Neighborhood Hits	170
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

CRUM2_HUMAN
NC score	0.428799 (rank : 93)	θ value	0.0252991 (rank : 261)
Query Neighborhood Hits	613	Target Neighborhood Hits	453	Shared Neighborhood Hits	289
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

FBLN1_HUMAN
NC score	0.427126 (rank : 94)	θ value	1.17247e-07 (rank : 89)
Query Neighborhood Hits	613	Target Neighborhood Hits	324	Shared Neighborhood Hits	240
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

DNER_MOUSE
NC score	0.427111 (rank : 95)	θ value	0.00134147 (rank : 193)
Query Neighborhood Hits	613	Target Neighborhood Hits	413	Shared Neighborhood Hits	268
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

WIF1_HUMAN
NC score	0.424427 (rank : 96)	θ value	0.0193708 (rank : 257)
Query Neighborhood Hits	613	Target Neighborhood Hits	392	Shared Neighborhood Hits	281
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

DLK_HUMAN
NC score	0.424198 (rank : 97)	θ value	0.21417 (rank : 337)
Query Neighborhood Hits	613	Target Neighborhood Hits	401	Shared Neighborhood Hits	279
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL3_HUMAN
NC score	0.419481 (rank : 98)	θ value	0.0563607 (rank : 287)
Query Neighborhood Hits	613	Target Neighborhood Hits	419	Shared Neighborhood Hits	265
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLK_MOUSE
NC score	0.418973 (rank : 99)	θ value	0.365318 (rank : 366)
Query Neighborhood Hits	613	Target Neighborhood Hits	374	Shared Neighborhood Hits	258
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

AGRIN_HUMAN
NC score	0.416422 (rank : 100)	θ value	0.00035302 (rank : 172)
Query Neighborhood Hits	613	Target Neighborhood Hits	582	Shared Neighborhood Hits	298
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

TRBM_MOUSE
NC score	0.415802 (rank : 101)	θ value	0.000461057 (rank : 179)
Query Neighborhood Hits	613	Target Neighborhood Hits	361	Shared Neighborhood Hits	246
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

EGFL9_HUMAN
NC score	0.415766 (rank : 102)	θ value	0.0148317 (rank : 243)
Query Neighborhood Hits	613	Target Neighborhood Hits	365	Shared Neighborhood Hits	261
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

TRBM_HUMAN
NC score	0.414143 (rank : 103)	θ value	0.00298849 (rank : 214)
Query Neighborhood Hits	613	Target Neighborhood Hits	339	Shared Neighborhood Hits	236
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LAMB1_MOUSE
NC score	0.414048 (rank : 104)	θ value	3.08544e-08 (rank : 85)
Query Neighborhood Hits	613	Target Neighborhood Hits	919	Shared Neighborhood Hits	291
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

EGFL9_MOUSE
NC score	0.413178 (rank : 105)	θ value	0.0113563 (rank : 236)
Query Neighborhood Hits	613	Target Neighborhood Hits	379	Shared Neighborhood Hits	264
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

USH2A_MOUSE
NC score	0.412504 (rank : 106)	θ value	2.69671e-12 (rank : 41)
Query Neighborhood Hits	613	Target Neighborhood Hits	626	Shared Neighborhood Hits	317
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

MATN2_HUMAN
NC score	0.411164 (rank : 107)	θ value	1.02475e-11 (rank : 44)
Query Neighborhood Hits	613	Target Neighborhood Hits	365	Shared Neighborhood Hits	232
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

KR510_HUMAN
NC score	0.411056 (rank : 108)	θ value	0.00035302 (rank : 175)
Query Neighborhood Hits	613	Target Neighborhood Hits	217	Shared Neighborhood Hits	153
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

FBLN5_MOUSE
NC score	0.410532 (rank : 109)	θ value	1.53129e-07 (rank : 91)
Query Neighborhood Hits	613	Target Neighborhood Hits	317	Shared Neighborhood Hits	240
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

LAMA2_HUMAN
NC score	0.410497 (rank : 110)	θ value	1.06045e-08 (rank : 78)
Query Neighborhood Hits	613	Target Neighborhood Hits	1092	Shared Neighborhood Hits	351
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

DLL3_MOUSE
NC score	0.410207 (rank : 111)	θ value	0.163984 (rank : 322)
Query Neighborhood Hits	613	Target Neighborhood Hits	399	Shared Neighborhood Hits	256
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

FBLN5_HUMAN
NC score	0.409023 (rank : 112)	θ value	3.41135e-07 (rank : 98)
Query Neighborhood Hits	613	Target Neighborhood Hits	329	Shared Neighborhood Hits	247
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

TENA_HUMAN
NC score	0.407312 (rank : 113)	θ value	1.133e-10 (rank : 56)
Query Neighborhood Hits	613	Target Neighborhood Hits	631	Shared Neighborhood Hits	312
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENX_HUMAN
NC score	0.406180 (rank : 114)	θ value	1.58096e-12 (rank : 40)
Query Neighborhood Hits	613	Target Neighborhood Hits	789	Shared Neighborhood Hits	333
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LAMC2_MOUSE
NC score	0.405718 (rank : 115)	θ value	9.92553e-07 (rank : 109)
Query Neighborhood Hits	613	Target Neighborhood Hits	614	Shared Neighborhood Hits	303
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

MATN2_MOUSE
NC score	0.404835 (rank : 116)	θ value	3.89403e-11 (rank : 47)
Query Neighborhood Hits	613	Target Neighborhood Hits	356	Shared Neighborhood Hits	226
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

C1QR1_HUMAN
NC score	0.404570 (rank : 117)	θ value	9.29e-05 (rank : 149)
Query Neighborhood Hits	613	Target Neighborhood Hits	493	Shared Neighborhood Hits	252
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

LAMB3_MOUSE
NC score	0.404175 (rank : 118)	θ value	5.26297e-08 (rank : 87)
Query Neighborhood Hits	613	Target Neighborhood Hits	444	Shared Neighborhood Hits	230
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

KRA56_HUMAN
NC score	0.403356 (rank : 119)	θ value	0.0563607 (rank : 292)
Query Neighborhood Hits	613	Target Neighborhood Hits	207	Shared Neighborhood Hits	155
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LRP1_HUMAN
NC score	0.400591 (rank : 120)	θ value	6.64225e-11 (rank : 53)
Query Neighborhood Hits	613	Target Neighborhood Hits	617	Shared Neighborhood Hits	353
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

KR511_HUMAN
NC score	0.399368 (rank : 121)	θ value	0.62314 (rank : 404)
Query Neighborhood Hits	613	Target Neighborhood Hits	231	Shared Neighborhood Hits	160
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

TENA_MOUSE
NC score	0.397252 (rank : 122)	θ value	3.29651e-10 (rank : 64)
Query Neighborhood Hits	613	Target Neighborhood Hits	596	Shared Neighborhood Hits	308
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

LAMC1_MOUSE
NC score	0.397213 (rank : 123)	θ value	6.43352e-06 (rank : 126)
Query Neighborhood Hits	613	Target Neighborhood Hits	856	Shared Neighborhood Hits	301
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMB1_HUMAN
NC score	0.397187 (rank : 124)	θ value	2.13673e-09 (rank : 71)
Query Neighborhood Hits	613	Target Neighborhood Hits	1018	Shared Neighborhood Hits	300
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

FBLN4_HUMAN
NC score	0.396042 (rank : 125)	θ value	0.00228821 (rank : 205)
Query Neighborhood Hits	613	Target Neighborhood Hits	278	Shared Neighborhood Hits	210
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
NC score	0.394571 (rank : 126)	θ value	0.00035302 (rank : 174)
Query Neighborhood Hits	613	Target Neighborhood Hits	270	Shared Neighborhood Hits	206
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

LRP1B_HUMAN
NC score	0.391518 (rank : 127)	θ value	7.59969e-07 (rank : 107)
Query Neighborhood Hits	613	Target Neighborhood Hits	602	Shared Neighborhood Hits	338
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

C1QR1_MOUSE
NC score	0.390673 (rank : 128)	θ value	0.00298849 (rank : 209)
Query Neighborhood Hits	613	Target Neighborhood Hits	342	Shared Neighborhood Hits	230
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

LAMA2_MOUSE
NC score	0.389678 (rank : 129)	θ value	6.64225e-11 (rank : 51)
Query Neighborhood Hits	613	Target Neighborhood Hits	1198	Shared Neighborhood Hits	339
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LRP1B_MOUSE
NC score	0.388738 (rank : 130)	θ value	5.81887e-07 (rank : 105)
Query Neighborhood Hits	613	Target Neighborhood Hits	606	Shared Neighborhood Hits	338
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LAMC1_HUMAN
NC score	0.388716 (rank : 131)	θ value	4.45536e-07 (rank : 103)
Query Neighborhood Hits	613	Target Neighborhood Hits	922	Shared Neighborhood Hits	304
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

FBLN3_HUMAN
NC score	0.385477 (rank : 132)	θ value	0.0563607 (rank : 288)
Query Neighborhood Hits	613	Target Neighborhood Hits	293	Shared Neighborhood Hits	219
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

LAMC2_HUMAN
NC score	0.384119 (rank : 133)	θ value	0.00175202 (rank : 201)
Query Neighborhood Hits	613	Target Neighborhood Hits	715	Shared Neighborhood Hits	290
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMB3_HUMAN
NC score	0.384006 (rank : 134)	θ value	1.43324e-05 (rank : 131)
Query Neighborhood Hits	613	Target Neighborhood Hits	461	Shared Neighborhood Hits	203
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMA3_MOUSE
NC score	0.383316 (rank : 135)	θ value	1.43324e-05 (rank : 130)
Query Neighborhood Hits	613	Target Neighborhood Hits	859	Shared Neighborhood Hits	322
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

USH2A_HUMAN
NC score	0.380372 (rank : 136)	θ value	1.38499e-08 (rank : 81)
Query Neighborhood Hits	613	Target Neighborhood Hits	600	Shared Neighborhood Hits	290
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

NID2_HUMAN
NC score	0.380338 (rank : 137)	θ value	0.00102713 (rank : 192)
Query Neighborhood Hits	613	Target Neighborhood Hits	456	Shared Neighborhood Hits	241
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

LRP2_HUMAN
NC score	0.379265 (rank : 138)	θ value	8.11959e-09 (rank : 77)
Query Neighborhood Hits	613	Target Neighborhood Hits	573	Shared Neighborhood Hits	335
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

FBLN3_MOUSE
NC score	0.376114 (rank : 139)	θ value	0.125558 (rank : 308)
Query Neighborhood Hits	613	Target Neighborhood Hits	279	Shared Neighborhood Hits	205
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

GRN_HUMAN
NC score	0.373714 (rank : 140)	θ value	0.00102713 (rank : 189)
Query Neighborhood Hits	613	Target Neighborhood Hits	268	Shared Neighborhood Hits	204
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KR101_HUMAN
NC score	0.372550 (rank : 141)	θ value	0.0148317 (rank : 246)
Query Neighborhood Hits	613	Target Neighborhood Hits	261	Shared Neighborhood Hits	191
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

CUBN_HUMAN
NC score	0.372166 (rank : 142)	θ value	5.44631e-05 (rank : 144)
Query Neighborhood Hits	613	Target Neighborhood Hits	482	Shared Neighborhood Hits	277
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
NC score	0.370156 (rank : 143)	θ value	0.000602161 (rank : 181)
Query Neighborhood Hits	613	Target Neighborhood Hits	477	Shared Neighborhood Hits	273
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

UROM_HUMAN
NC score	0.370102 (rank : 144)	θ value	0.0193708 (rank : 256)
Query Neighborhood Hits	613	Target Neighborhood Hits	284	Shared Neighborhood Hits	211
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

EGF_MOUSE
NC score	0.369676 (rank : 145)	θ value	0.0252991 (rank : 262)
Query Neighborhood Hits	613	Target Neighborhood Hits	358	Shared Neighborhood Hits	242
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

GRN_MOUSE
NC score	0.369197 (rank : 146)	θ value	0.00869519 (rank : 231)
Query Neighborhood Hits	613	Target Neighborhood Hits	248	Shared Neighborhood Hits	197
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

UROM_MOUSE
NC score	0.369128 (rank : 147)	θ value	0.000158464 (rank : 158)
Query Neighborhood Hits	613	Target Neighborhood Hits	276	Shared Neighborhood Hits	212
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

PROS_HUMAN
NC score	0.367403 (rank : 148)	θ value	0.00665767 (rank : 228)
Query Neighborhood Hits	613	Target Neighborhood Hits	340	Shared Neighborhood Hits	239
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
NC score	0.366977 (rank : 149)	θ value	0.0113563 (rank : 237)
Query Neighborhood Hits	613	Target Neighborhood Hits	330	Shared Neighborhood Hits	233
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

GAS6_HUMAN
NC score	0.366883 (rank : 150)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	613	Target Neighborhood Hits	348	Shared Neighborhood Hits	241
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

NAGPA_HUMAN
NC score	0.366323 (rank : 151)	θ value	0.47712 (rank : 388)
Query Neighborhood Hits	613	Target Neighborhood Hits	282	Shared Neighborhood Hits	223
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

SSPO_MOUSE
NC score	0.365113 (rank : 152)	θ value	1.06045e-08 (rank : 79)
Query Neighborhood Hits	613	Target Neighborhood Hits	800	Shared Neighborhood Hits	372
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

GAS6_MOUSE
NC score	0.364506 (rank : 153)	θ value	8.99809 (rank : 597)
Query Neighborhood Hits	613	Target Neighborhood Hits	343	Shared Neighborhood Hits	236
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

NID2_MOUSE
NC score	0.363665 (rank : 154)	θ value	0.0961366 (rank : 305)
Query Neighborhood Hits	613	Target Neighborhood Hits	338	Shared Neighborhood Hits	226
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NID1_MOUSE
NC score	0.363236 (rank : 155)	θ value	0.00665767 (rank : 226)
Query Neighborhood Hits	613	Target Neighborhood Hits	335	Shared Neighborhood Hits	227
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_HUMAN
NC score	0.362152 (rank : 156)	θ value	0.279714 (rank : 359)
Query Neighborhood Hits	613	Target Neighborhood Hits	329	Shared Neighborhood Hits	228
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NAGPA_MOUSE
NC score	0.358982 (rank : 157)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	613	Target Neighborhood Hits	308	Shared Neighborhood Hits	239
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

EGF_HUMAN
NC score	0.358695 (rank : 158)	θ value	0.0148317 (rank : 244)
Query Neighborhood Hits	613	Target Neighborhood Hits	343	Shared Neighborhood Hits	231
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

LDLR_HUMAN
NC score	0.354900 (rank : 159)	θ value	6.43352e-06 (rank : 127)
Query Neighborhood Hits	613	Target Neighborhood Hits	375	Shared Neighborhood Hits	260
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

KR105_HUMAN
NC score	0.354656 (rank : 160)	θ value	0.00298849 (rank : 212)
Query Neighborhood Hits	613	Target Neighborhood Hits	271	Shared Neighborhood Hits	198
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

RSPO3_HUMAN
NC score	0.351851 (rank : 161)	θ value	9.59137e-10 (rank : 68)
Query Neighborhood Hits	613	Target Neighborhood Hits	128	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

NTNG2_HUMAN
NC score	0.351126 (rank : 162)	θ value	0.00298849 (rank : 213)
Query Neighborhood Hits	613	Target Neighborhood Hits	276	Shared Neighborhood Hits	197
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

KR10B_HUMAN
NC score	0.349331 (rank : 163)	θ value	0.0193708 (rank : 253)
Query Neighborhood Hits	613	Target Neighborhood Hits	269	Shared Neighborhood Hits	189
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

ITB5_MOUSE
NC score	0.347702 (rank : 164)	θ value	4.1701e-05 (rank : 140)
Query Neighborhood Hits	613	Target Neighborhood Hits	329	Shared Neighborhood Hits	267
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

NTNG2_MOUSE
NC score	0.346512 (rank : 165)	θ value	0.365318 (rank : 373)
Query Neighborhood Hits	613	Target Neighborhood Hits	276	Shared Neighborhood Hits	207
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LDLR_MOUSE
NC score	0.345989 (rank : 166)	θ value	2.61198e-07 (rank : 97)
Query Neighborhood Hits	613	Target Neighborhood Hits	382	Shared Neighborhood Hits	256
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

KR171_HUMAN
NC score	0.344457 (rank : 167)	θ value	3.0926 (rank : 502)
Query Neighborhood Hits	613	Target Neighborhood Hits	144	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

VLDLR_HUMAN
NC score	0.343891 (rank : 168)	θ value	0.365318 (rank : 377)
Query Neighborhood Hits	613	Target Neighborhood Hits	383	Shared Neighborhood Hits	253
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LAMA4_MOUSE
NC score	0.343470 (rank : 169)	θ value	2.21117e-06 (rank : 116)
Query Neighborhood Hits	613	Target Neighborhood Hits	584	Shared Neighborhood Hits	207
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

EGFL7_HUMAN
NC score	0.341973 (rank : 170)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	613	Target Neighborhood Hits	325	Shared Neighborhood Hits	230
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

RSPO3_MOUSE
NC score	0.340799 (rank : 171)	θ value	3.29651e-10 (rank : 63)
Query Neighborhood Hits	613	Target Neighborhood Hits	120	Shared Neighborhood Hits	89
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

KR102_HUMAN
NC score	0.340505 (rank : 172)	θ value	8.99809 (rank : 599)
Query Neighborhood Hits	613	Target Neighborhood Hits	264	Shared Neighborhood Hits	195
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

ITB3_HUMAN
NC score	0.340281 (rank : 173)	θ value	0.000270298 (rank : 165)
Query Neighborhood Hits	613	Target Neighborhood Hits	325	Shared Neighborhood Hits	266
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

VLDLR_MOUSE
NC score	0.339468 (rank : 174)	θ value	1.38821 (rank : 458)
Query Neighborhood Hits	613	Target Neighborhood Hits	360	Shared Neighborhood Hits	239
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ITB6_MOUSE
NC score	0.338829 (rank : 175)	θ value	0.00298849 (rank : 211)
Query Neighborhood Hits	613	Target Neighborhood Hits	341	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

LRP8_MOUSE
NC score	0.338237 (rank : 176)	θ value	0.00102713 (rank : 191)
Query Neighborhood Hits	613	Target Neighborhood Hits	385	Shared Neighborhood Hits	246
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

RSPO4_HUMAN
NC score	0.337642 (rank : 177)	θ value	4.30538e-10 (rank : 65)
Query Neighborhood Hits	613	Target Neighborhood Hits	110	Shared Neighborhood Hits	91
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

ITB5_HUMAN
NC score	0.337258 (rank : 178)	θ value	1.87187e-05 (rank : 133)
Query Neighborhood Hits	613	Target Neighborhood Hits	310	Shared Neighborhood Hits	247
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

KR108_HUMAN
NC score	0.336990 (rank : 179)	θ value	0.000786445 (rank : 185)
Query Neighborhood Hits	613	Target Neighborhood Hits	226	Shared Neighborhood Hits	163
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

LAMA3_HUMAN
NC score	0.336738 (rank : 180)	θ value	0.000602161 (rank : 182)
Query Neighborhood Hits	613	Target Neighborhood Hits	760	Shared Neighborhood Hits	245
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

NTNG1_HUMAN
NC score	0.336314 (rank : 181)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	613	Target Neighborhood Hits	247	Shared Neighborhood Hits	188
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

ITB2_MOUSE
NC score	0.334906 (rank : 182)	θ value	9.29e-05 (rank : 150)
Query Neighborhood Hits	613	Target Neighborhood Hits	326	Shared Neighborhood Hits	263
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

NTNG1_MOUSE
NC score	0.332252 (rank : 183)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	613	Target Neighborhood Hits	246	Shared Neighborhood Hits	186
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

MATN3_HUMAN
NC score	0.330952 (rank : 184)	θ value	4.1701e-05 (rank : 141)
Query Neighborhood Hits	613	Target Neighborhood Hits	268	Shared Neighborhood Hits	177
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

ITB7_HUMAN
NC score	0.330007 (rank : 185)	θ value	0.00134147 (rank : 195)
Query Neighborhood Hits	613	Target Neighborhood Hits	290	Shared Neighborhood Hits	234
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

RSPO4_MOUSE
NC score	0.328735 (rank : 186)	θ value	4.76016e-09 (rank : 73)
Query Neighborhood Hits	613	Target Neighborhood Hits	110	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

ITB3_MOUSE
NC score	0.328257 (rank : 187)	θ value	9.29e-05 (rank : 151)
Query Neighborhood Hits	613	Target Neighborhood Hits	319	Shared Neighborhood Hits	253
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

EGFL7_MOUSE
NC score	0.326948 (rank : 188)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	613	Target Neighborhood Hits	287	Shared Neighborhood Hits	212
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

ITB7_MOUSE
NC score	0.326051 (rank : 189)	θ value	0.00175202 (rank : 200)
Query Neighborhood Hits	613	Target Neighborhood Hits	277	Shared Neighborhood Hits	219
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

SUSD1_HUMAN
NC score	0.325618 (rank : 190)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	613	Target Neighborhood Hits	285	Shared Neighborhood Hits	182
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

ITB6_HUMAN
NC score	0.324264 (rank : 191)	θ value	1.38821 (rank : 453)
Query Neighborhood Hits	613	Target Neighborhood Hits	318	Shared Neighborhood Hits	249
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

LAMA4_HUMAN
NC score	0.323681 (rank : 192)	θ value	1.29631e-06 (rank : 112)
Query Neighborhood Hits	613	Target Neighborhood Hits	708	Shared Neighborhood Hits	201
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

KR109_HUMAN
NC score	0.323582 (rank : 193)	θ value	0.279714 (rank : 351)
Query Neighborhood Hits	613	Target Neighborhood Hits	226	Shared Neighborhood Hits	171
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

EMR1_HUMAN
NC score	0.323330 (rank : 194)	θ value	0.0431538 (rank : 280)
Query Neighborhood Hits	613	Target Neighborhood Hits	382	Shared Neighborhood Hits	220
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

KRA45_HUMAN
NC score	0.323108 (rank : 195)	θ value	2.44474e-05 (rank : 139)
Query Neighborhood Hits	613	Target Neighborhood Hits	194	Shared Neighborhood Hits	148
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

MATN3_MOUSE
NC score	0.322810 (rank : 196)	θ value	0.00228821 (rank : 206)
Query Neighborhood Hits	613	Target Neighborhood Hits	261	Shared Neighborhood Hits	180
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
NC score	0.321958 (rank : 197)	θ value	0.000121331 (rank : 156)
Query Neighborhood Hits	613	Target Neighborhood Hits	287	Shared Neighborhood Hits	194
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

LRP8_HUMAN
NC score	0.320552 (rank : 198)	θ value	0.00869519 (rank : 232)
Query Neighborhood Hits	613	Target Neighborhood Hits	346	Shared Neighborhood Hits	223
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MATN4_MOUSE
NC score	0.320347 (rank : 199)	θ value	1.87187e-05 (rank : 136)
Query Neighborhood Hits	613	Target Neighborhood Hits	277	Shared Neighborhood Hits	183
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

COMP_MOUSE
NC score	0.320053 (rank : 200)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	613	Target Neighborhood Hits	290	Shared Neighborhood Hits	222
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

ATRN_MOUSE
NC score	0.318512 (rank : 201)	θ value	0.00020696 (rank : 159)
Query Neighborhood Hits	613	Target Neighborhood Hits	519	Shared Neighborhood Hits	246
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

NFX1_HUMAN
NC score	0.315834 (rank : 202)	θ value	0.000786445 (rank : 186)
Query Neighborhood Hits	613	Target Neighborhood Hits	405	Shared Neighborhood Hits	209
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

LRP4_HUMAN
NC score	0.315795 (rank : 203)	θ value	1.87187e-05 (rank : 135)
Query Neighborhood Hits	613	Target Neighborhood Hits	355	Shared Neighborhood Hits	232
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

TSP4_MOUSE
NC score	0.315560 (rank : 204)	θ value	0.47712 (rank : 392)
Query Neighborhood Hits	613	Target Neighborhood Hits	276	Shared Neighborhood Hits	215
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

LRP4_MOUSE
NC score	0.315051 (rank : 205)	θ value	0.00175202 (rank : 202)
Query Neighborhood Hits	613	Target Neighborhood Hits	351	Shared Neighborhood Hits	226
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

ITB1_HUMAN
NC score	0.314379 (rank : 206)	θ value	0.0431538 (rank : 282)
Query Neighborhood Hits	613	Target Neighborhood Hits	298	Shared Neighborhood Hits	235
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

RSPO2_MOUSE
NC score	0.313401 (rank : 207)	θ value	2.36244e-08 (rank : 83)
Query Neighborhood Hits	613	Target Neighborhood Hits	88	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

ITB2_HUMAN
NC score	0.313314 (rank : 208)	θ value	0.00134147 (rank : 194)
Query Neighborhood Hits	613	Target Neighborhood Hits	282	Shared Neighborhood Hits	236
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

RSPO2_HUMAN
NC score	0.312636 (rank : 209)	θ value	1.38499e-08 (rank : 80)
Query Neighborhood Hits	613	Target Neighborhood Hits	90	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

KRA47_HUMAN
NC score	0.312306 (rank : 210)	θ value	0.0563607 (rank : 291)
Query Neighborhood Hits	613	Target Neighborhood Hits	204	Shared Neighborhood Hits	143
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

COMP_HUMAN
NC score	0.311731 (rank : 211)	θ value	0.163984 (rank : 320)
Query Neighborhood Hits	613	Target Neighborhood Hits	258	Shared Neighborhood Hits	206
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

KRA93_HUMAN
NC score	0.310695 (rank : 212)	θ value	0.0431538 (rank : 283)
Query Neighborhood Hits	613	Target Neighborhood Hits	203	Shared Neighborhood Hits	152
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

ITB1_MOUSE
NC score	0.309646 (rank : 213)	θ value	1.87187e-05 (rank : 132)
Query Neighborhood Hits	613	Target Neighborhood Hits	283	Shared Neighborhood Hits	224
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ATRN_HUMAN
NC score	0.309001 (rank : 214)	θ value	0.0330416 (rank : 271)
Query Neighborhood Hits	613	Target Neighborhood Hits	525	Shared Neighborhood Hits	246
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

TSP4_HUMAN
NC score	0.308581 (rank : 215)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	613	Target Neighborhood Hits	277	Shared Neighborhood Hits	204
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

KR10C_HUMAN
NC score	0.306399 (rank : 216)	θ value	4.03905 (rank : 526)
Query Neighborhood Hits	613	Target Neighborhood Hits	219	Shared Neighborhood Hits	164
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

EGFL8_HUMAN
NC score	0.304980 (rank : 217)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	613	Target Neighborhood Hits	270	Shared Neighborhood Hits	186
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

CD248_HUMAN
NC score	0.304369 (rank : 218)	θ value	1.38821 (rank : 446)
Query Neighborhood Hits	613	Target Neighborhood Hits	679	Shared Neighborhood Hits	211
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

RSPO1_HUMAN
NC score	0.303110 (rank : 219)	θ value	1.33837e-11 (rank : 45)
Query Neighborhood Hits	613	Target Neighborhood Hits	101	Shared Neighborhood Hits	76
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

VWF_HUMAN
NC score	0.302913 (rank : 220)	θ value	3.77169e-06 (rank : 125)
Query Neighborhood Hits	613	Target Neighborhood Hits	396	Shared Neighborhood Hits	242
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CD248_MOUSE
NC score	0.301747 (rank : 221)	θ value	5.27518 (rank : 543)
Query Neighborhood Hits	613	Target Neighborhood Hits	578	Shared Neighborhood Hits	193
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

KRA98_HUMAN
NC score	0.301615 (rank : 222)	θ value	0.163984 (rank : 323)
Query Neighborhood Hits	613	Target Neighborhood Hits	185	Shared Neighborhood Hits	142
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

NET4_HUMAN
NC score	0.301504 (rank : 223)	θ value	0.62314 (rank : 405)
Query Neighborhood Hits	613	Target Neighborhood Hits	191	Shared Neighborhood Hits	162
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET2_HUMAN
NC score	0.301332 (rank : 224)	θ value	0.0148317 (rank : 248)
Query Neighborhood Hits	613	Target Neighborhood Hits	194	Shared Neighborhood Hits	148
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

PGBM_MOUSE
NC score	0.301058 (rank : 225)	θ value	1.87187e-05 (rank : 137)
Query Neighborhood Hits	613	Target Neighborhood Hits	1073	Shared Neighborhood Hits	336
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

EGFL8_MOUSE
NC score	0.301009 (rank : 226)	θ value	5.27518 (rank : 548)
Query Neighborhood Hits	613	Target Neighborhood Hits	266	Shared Neighborhood Hits	191
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EMR2_HUMAN
NC score	0.300321 (rank : 227)	θ value	1.38821 (rank : 449)
Query Neighborhood Hits	613	Target Neighborhood Hits	345	Shared Neighborhood Hits	206
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

NET4_MOUSE
NC score	0.299934 (rank : 228)	θ value	0.47712 (rank : 390)
Query Neighborhood Hits	613	Target Neighborhood Hits	180	Shared Neighborhood Hits	153
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NET2_MOUSE
NC score	0.299009 (rank : 229)	θ value	0.0563607 (rank : 294)
Query Neighborhood Hits	613	Target Neighborhood Hits	193	Shared Neighborhood Hits	151
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

KRA92_HUMAN
NC score	0.298689 (rank : 230)	θ value	0.21417 (rank : 338)
Query Neighborhood Hits	613	Target Neighborhood Hits	198	Shared Neighborhood Hits	152
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

EMR1_MOUSE
NC score	0.298254 (rank : 231)	θ value	0.47712 (rank : 384)
Query Neighborhood Hits	613	Target Neighborhood Hits	349	Shared Neighborhood Hits	199
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

CD97_HUMAN
NC score	0.298004 (rank : 232)	θ value	1.06291 (rank : 432)
Query Neighborhood Hits	613	Target Neighborhood Hits	353	Shared Neighborhood Hits	210
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

KRA94_HUMAN
NC score	0.296035 (rank : 233)	θ value	5.27518 (rank : 553)
Query Neighborhood Hits	613	Target Neighborhood Hits	204	Shared Neighborhood Hits	167
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

HHIP_HUMAN
NC score	0.295543 (rank : 234)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	613	Target Neighborhood Hits	249	Shared Neighborhood Hits	202
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

VWF_MOUSE
NC score	0.291728 (rank : 235)	θ value	4.1701e-05 (rank : 143)
Query Neighborhood Hits	613	Target Neighborhood Hits	381	Shared Neighborhood Hits	238
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ITB4_HUMAN
NC score	0.290198 (rank : 236)	θ value	0.279714 (rank : 350)
Query Neighborhood Hits	613	Target Neighborhood Hits	458	Shared Neighborhood Hits	236
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

PGBM_HUMAN
NC score	0.290158 (rank : 237)	θ value	3.77169e-06 (rank : 122)
Query Neighborhood Hits	613	Target Neighborhood Hits	1113	Shared Neighborhood Hits	323
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SLIT1_HUMAN
NC score	0.287923 (rank : 238)	θ value	0.163984 (rank : 327)
Query Neighborhood Hits	613	Target Neighborhood Hits	700	Shared Neighborhood Hits	272
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

TSP3_MOUSE
NC score	0.287154 (rank : 239)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	613	Target Neighborhood Hits	247	Shared Neighborhood Hits	189
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

SLIT1_MOUSE
NC score	0.286867 (rank : 240)	θ value	4.03905 (rank : 531)
Query Neighborhood Hits	613	Target Neighborhood Hits	715	Shared Neighborhood Hits	278
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

KR412_HUMAN
NC score	0.286480 (rank : 241)	θ value	0.125558 (rank : 310)
Query Neighborhood Hits	613	Target Neighborhood Hits	178	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA13_HUMAN
NC score	0.286030 (rank : 242)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	613	Target Neighborhood Hits	144	Shared Neighborhood Hits	115
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

ITB8_HUMAN
NC score	0.284215 (rank : 243)	θ value	9.29e-05 (rank : 152)
Query Neighborhood Hits	613	Target Neighborhood Hits	280	Shared Neighborhood Hits	222
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

RSPO1_MOUSE
NC score	0.282752 (rank : 244)	θ value	8.67504e-11 (rank : 54)
Query Neighborhood Hits	613	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

TSP3_HUMAN
NC score	0.282674 (rank : 245)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	613	Target Neighborhood Hits	250	Shared Neighborhood Hits	180
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

SORL_MOUSE
NC score	0.282000 (rank : 246)	θ value	0.000461057 (rank : 178)
Query Neighborhood Hits	613	Target Neighborhood Hits	439	Shared Neighborhood Hits	231
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TSP1_HUMAN
NC score	0.281521 (rank : 247)	θ value	0.000602161 (rank : 183)
Query Neighborhood Hits	613	Target Neighborhood Hits	389	Shared Neighborhood Hits	246
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
NC score	0.280236 (rank : 248)	θ value	0.00869519 (rank : 234)
Query Neighborhood Hits	613	Target Neighborhood Hits	396	Shared Neighborhood Hits	247
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

KR10A_HUMAN
NC score	0.279667 (rank : 249)	θ value	0.0961366 (rank : 304)
Query Neighborhood Hits	613	Target Neighborhood Hits	232	Shared Neighborhood Hits	179
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

HHIP_MOUSE
NC score	0.278283 (rank : 250)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	613	Target Neighborhood Hits	219	Shared Neighborhood Hits	170
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KRA44_HUMAN
NC score	0.275917 (rank : 251)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	613	Target Neighborhood Hits	162	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

SLIT2_HUMAN
NC score	0.275899 (rank : 252)	θ value	0.62314 (rank : 406)
Query Neighborhood Hits	613	Target Neighborhood Hits	708	Shared Neighborhood Hits	274
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

MUC5B_HUMAN
NC score	0.274716 (rank : 253)	θ value	0.00390308 (rank : 217)
Query Neighborhood Hits	613	Target Neighborhood Hits	1020	Shared Neighborhood Hits	272
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

KR414_HUMAN
NC score	0.274590 (rank : 254)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	613	Target Neighborhood Hits	199	Shared Neighborhood Hits	144
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

SORL_HUMAN
NC score	0.274258 (rank : 255)	θ value	0.000270298 (rank : 166)
Query Neighborhood Hits	613	Target Neighborhood Hits	440	Shared Neighborhood Hits	224
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SLIT3_MOUSE
NC score	0.273247 (rank : 256)	θ value	1.38821 (rank : 456)
Query Neighborhood Hits	613	Target Neighborhood Hits	700	Shared Neighborhood Hits	274
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

KR103_HUMAN
NC score	0.271723 (rank : 257)	θ value	0.62314 (rank : 403)
Query Neighborhood Hits	613	Target Neighborhood Hits	212	Shared Neighborhood Hits	154
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

SLIT2_MOUSE
NC score	0.271354 (rank : 258)	θ value	0.47712 (rank : 391)
Query Neighborhood Hits	613	Target Neighborhood Hits	684	Shared Neighborhood Hits	261
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

KRA99_HUMAN
NC score	0.271155 (rank : 259)	θ value	3.0926 (rank : 503)
Query Neighborhood Hits	613	Target Neighborhood Hits	173	Shared Neighborhood Hits	134
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

HMCN1_HUMAN
NC score	0.268326 (rank : 260)	θ value	1.29631e-06 (rank : 110)
Query Neighborhood Hits	613	Target Neighborhood Hits	983	Shared Neighborhood Hits	284
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KRA11_HUMAN
NC score	0.268261 (rank : 261)	θ value	2.36792 (rank : 480)
Query Neighborhood Hits	613	Target Neighborhood Hits	155	Shared Neighborhood Hits	118
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

NET1_HUMAN
NC score	0.267229 (rank : 262)	θ value	1.06291 (rank : 437)
Query Neighborhood Hits	613	Target Neighborhood Hits	149	Shared Neighborhood Hits	123
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

SLIT3_HUMAN
NC score	0.265886 (rank : 263)	θ value	1.38821 (rank : 455)
Query Neighborhood Hits	613	Target Neighborhood Hits	682	Shared Neighborhood Hits	261
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

NET1_MOUSE
NC score	0.265474 (rank : 264)	θ value	0.47712 (rank : 389)
Query Neighborhood Hits	613	Target Neighborhood Hits	151	Shared Neighborhood Hits	125
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

TENR_HUMAN
NC score	0.265286 (rank : 265)	θ value	0.163984 (rank : 328)
Query Neighborhood Hits	613	Target Neighborhood Hits	526	Shared Neighborhood Hits	265
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TNR16_HUMAN
NC score	0.262865 (rank : 266)	θ value	0.00020696 (rank : 161)
Query Neighborhood Hits	613	Target Neighborhood Hits	183	Shared Neighborhood Hits	142
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TENR_MOUSE
NC score	0.262251 (rank : 267)	θ value	2.36792 (rank : 487)
Query Neighborhood Hits	613	Target Neighborhood Hits	531	Shared Neighborhood Hits	267
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

BMPER_MOUSE
NC score	0.261261 (rank : 268)	θ value	0.21417 (rank : 336)
Query Neighborhood Hits	613	Target Neighborhood Hits	194	Shared Neighborhood Hits	144
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

EDIL3_MOUSE
NC score	0.258948 (rank : 269)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	613	Target Neighborhood Hits	317	Shared Neighborhood Hits	202
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

TNR16_MOUSE
NC score	0.254332 (rank : 270)	θ value	0.00020696 (rank : 162)
Query Neighborhood Hits	613	Target Neighborhood Hits	178	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR25_HUMAN
NC score	0.253054 (rank : 271)	θ value	4.1701e-05 (rank : 142)
Query Neighborhood Hits	613	Target Neighborhood Hits	172	Shared Neighborhood Hits	121
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

EDIL3_HUMAN
NC score	0.250534 (rank : 272)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	613	Target Neighborhood Hits	292	Shared Neighborhood Hits	183
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

ZAN_HUMAN
NC score	0.250295 (rank : 273)	θ value	0.47712 (rank : 394)
Query Neighborhood Hits	613	Target Neighborhood Hits	679	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CD97_MOUSE
NC score	0.248456 (rank : 274)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	613	Target Neighborhood Hits	295	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

LCE1C_HUMAN
NC score	0.245497 (rank : 275)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	613	Target Neighborhood Hits	65	Shared Neighborhood Hits	50
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

TSP2_MOUSE
NC score	0.244846 (rank : 276)	θ value	0.279714 (rank : 362)
Query Neighborhood Hits	613	Target Neighborhood Hits	352	Shared Neighborhood Hits	225
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

LCE1B_HUMAN
NC score	0.244546 (rank : 277)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	613	Target Neighborhood Hits	58	Shared Neighborhood Hits	45
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

BMPER_HUMAN
NC score	0.243714 (rank : 278)	θ value	0.365318 (rank : 365)
Query Neighborhood Hits	613	Target Neighborhood Hits	175	Shared Neighborhood Hits	128
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

TSP2_HUMAN
NC score	0.241785 (rank : 279)	θ value	0.365318 (rank : 376)
Query Neighborhood Hits	613	Target Neighborhood Hits	359	Shared Neighborhood Hits	229
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ELTD1_MOUSE
NC score	0.238964 (rank : 280)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	613	Target Neighborhood Hits	288	Shared Neighborhood Hits	169
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

MT3_MOUSE
NC score	0.237646 (rank : 281)	θ value	0.0563607 (rank : 293)
Query Neighborhood Hits	613	Target Neighborhood Hits	68	Shared Neighborhood Hits	58
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

KRA15_HUMAN
NC score	0.237068 (rank : 282)	θ value	0.47712 (rank : 385)
Query Neighborhood Hits	613	Target Neighborhood Hits	126	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KR410_HUMAN
NC score	0.234413 (rank : 283)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	613	Target Neighborhood Hits	156	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

PROZ_MOUSE
NC score	0.231853 (rank : 284)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	613	Target Neighborhood Hits	410	Shared Neighborhood Hits	191
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

LYAM3_MOUSE
NC score	0.228907 (rank : 285)	θ value	0.279714 (rank : 353)
Query Neighborhood Hits	613	Target Neighborhood Hits	390	Shared Neighborhood Hits	207
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

PROZ_HUMAN
NC score	0.228889 (rank : 286)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	613	Target Neighborhood Hits	422	Shared Neighborhood Hits	199
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

TECTA_MOUSE
NC score	0.226567 (rank : 287)	θ value	5.44631e-05 (rank : 146)
Query Neighborhood Hits	613	Target Neighborhood Hits	244	Shared Neighborhood Hits	187
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

MT3_HUMAN
NC score	0.225354 (rank : 288)	θ value	0.0252991 (rank : 266)
Query Neighborhood Hits	613	Target Neighborhood Hits	82	Shared Neighborhood Hits	69
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

TENN_MOUSE
NC score	0.225132 (rank : 289)	θ value	0.0193708 (rank : 254)
Query Neighborhood Hits	613	Target Neighborhood Hits	484	Shared Neighborhood Hits	252
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

LCE1F_HUMAN
NC score	0.223467 (rank : 290)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	613	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

KRA42_HUMAN
NC score	0.222308 (rank : 291)	θ value	1.81305 (rank : 462)
Query Neighborhood Hits	613	Target Neighborhood Hits	149	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

MT4_MOUSE
NC score	0.221285 (rank : 292)	θ value	0.0431538 (rank : 284)
Query Neighborhood Hits	613	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

LCE1E_HUMAN
NC score	0.219719 (rank : 293)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	613	Target Neighborhood Hits	53	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LYAM2_MOUSE
NC score	0.215185 (rank : 294)	θ value	0.00035302 (rank : 176)
Query Neighborhood Hits	613	Target Neighborhood Hits	420	Shared Neighborhood Hits	229
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

TENN_HUMAN
NC score	0.212694 (rank : 295)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	613	Target Neighborhood Hits	453	Shared Neighborhood Hits	235
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TNR14_HUMAN
NC score	0.212307 (rank : 296)	θ value	0.279714 (rank : 361)
Query Neighborhood Hits	613	Target Neighborhood Hits	149	Shared Neighborhood Hits	127
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TECTA_HUMAN
NC score	0.211778 (rank : 297)	θ value	0.000270298 (rank : 169)
Query Neighborhood Hits	613	Target Neighborhood Hits	239	Shared Neighborhood Hits	176
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

LYAM2_HUMAN
NC score	0.209377 (rank : 298)	θ value	0.00020696 (rank : 160)
Query Neighborhood Hits	613	Target Neighborhood Hits	394	Shared Neighborhood Hits	208
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

TNR23_MOUSE
NC score	0.207410 (rank : 299)	θ value	0.00134147 (rank : 196)
Query Neighborhood Hits	613	Target Neighborhood Hits	114	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

CSPG2_MOUSE
NC score	0.206153 (rank : 300)	θ value	6.88961 (rank : 570)
Query Neighborhood Hits	613	Target Neighborhood Hits	711	Shared Neighborhood Hits	209
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_MOUSE
NC score	0.201783 (rank : 301)	θ value	2.36792 (rank : 479)
Query Neighborhood Hits	613	Target Neighborhood Hits	657	Shared Neighborhood Hits	207
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LCE1D_HUMAN
NC score	0.201258 (rank : 302)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	613	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LYAM3_HUMAN
NC score	0.201129 (rank : 303)	θ value	1.06291 (rank : 436)
Query Neighborhood Hits	613	Target Neighborhood Hits	378	Shared Neighborhood Hits	205
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CSPG2_HUMAN
NC score	0.201034 (rank : 304)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	613	Target Neighborhood Hits	681	Shared Neighborhood Hits	201
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

TNR9_MOUSE
NC score	0.200539 (rank : 305)	θ value	0.0113563 (rank : 240)
Query Neighborhood Hits	613	Target Neighborhood Hits	137	Shared Neighborhood Hits	116
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

ZNFX1_HUMAN
NC score	0.200218 (rank : 306)	θ value	5.81887e-07 (rank : 106)
Query Neighborhood Hits	613	Target Neighborhood Hits	308	Shared Neighborhood Hits	132
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

TNR4_MOUSE
NC score	0.199630 (rank : 307)	θ value	0.0431538 (rank : 286)
Query Neighborhood Hits	613	Target Neighborhood Hits	137	Shared Neighborhood Hits	115
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR9_HUMAN
NC score	0.197932 (rank : 308)	θ value	0.0193708 (rank : 255)
Query Neighborhood Hits	613	Target Neighborhood Hits	166	Shared Neighborhood Hits	136
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

CSPG3_HUMAN
NC score	0.197842 (rank : 309)	θ value	5.27518 (rank : 546)
Query Neighborhood Hits	613	Target Neighborhood Hits	676	Shared Neighborhood Hits	203
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LCE1A_HUMAN
NC score	0.196053 (rank : 310)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	613	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

MT4_HUMAN
NC score	0.195536 (rank : 311)	θ value	0.0330416 (rank : 274)
Query Neighborhood Hits	613	Target Neighborhood Hits	83	Shared Neighborhood Hits	69
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

CELR2_HUMAN
NC score	0.194042 (rank : 312)	θ value	0.0113563 (rank : 235)
Query Neighborhood Hits	613	Target Neighborhood Hits	657	Shared Neighborhood Hits	273
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CFC1_HUMAN
NC score	0.191850 (rank : 313)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	613	Target Neighborhood Hits	148	Shared Neighborhood Hits	105
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

ZNFX1_MOUSE
NC score	0.190925 (rank : 314)	θ value	0.000270298 (rank : 171)
Query Neighborhood Hits	613	Target Neighborhood Hits	407	Shared Neighborhood Hits	140
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

TNR7_HUMAN
NC score	0.189631 (rank : 315)	θ value	0.00228821 (rank : 208)
Query Neighborhood Hits	613	Target Neighborhood Hits	120	Shared Neighborhood Hits	106
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

MUC2_HUMAN
NC score	0.189525 (rank : 316)	θ value	0.00869519 (rank : 233)
Query Neighborhood Hits	613	Target Neighborhood Hits	906	Shared Neighborhood Hits	183
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CELR3_MOUSE
NC score	0.189108 (rank : 317)	θ value	0.47712 (rank : 383)
Query Neighborhood Hits	613	Target Neighborhood Hits	687	Shared Neighborhood Hits	268
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CELR3_HUMAN
NC score	0.188500 (rank : 318)	θ value	1.38821 (rank : 448)
Query Neighborhood Hits	613	Target Neighborhood Hits	680	Shared Neighborhood Hits	261
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

MT2_MOUSE
NC score	0.188037 (rank : 319)	θ value	0.163984 (rank : 325)
Query Neighborhood Hits	613	Target Neighborhood Hits	81	Shared Neighborhood Hits	66
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

FATH_HUMAN
NC score	0.187563 (rank : 320)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	613	Target Neighborhood Hits	570	Shared Neighborhood Hits	237
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TNR26_MOUSE
NC score	0.185788 (rank : 321)	θ value	0.125558 (rank : 317)
Query Neighborhood Hits	613	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

LCE3A_HUMAN
NC score	0.183606 (rank : 322)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	613	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

CELR1_MOUSE
NC score	0.183395 (rank : 323)	θ value	0.47712 (rank : 382)
Query Neighborhood Hits	613	Target Neighborhood Hits	617	Shared Neighborhood Hits	245
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR1_HUMAN
NC score	0.182970 (rank : 324)	θ value	1.38821 (rank : 447)
Query Neighborhood Hits	613	Target Neighborhood Hits	613	Shared Neighborhood Hits	240
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

TNR22_MOUSE
NC score	0.178621 (rank : 325)	θ value	0.00665767 (rank : 229)
Query Neighborhood Hits	613	Target Neighborhood Hits	97	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

LRP6_HUMAN
NC score	0.177163 (rank : 326)	θ value	3.0926 (rank : 504)
Query Neighborhood Hits	613	Target Neighborhood Hits	235	Shared Neighborhood Hits	138
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

TDGF1_MOUSE
NC score	0.177059 (rank : 327)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	613	Target Neighborhood Hits	146	Shared Neighborhood Hits	104
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

KRA24_HUMAN
NC score	0.176805 (rank : 328)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	613	Target Neighborhood Hits	192	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

CELR2_MOUSE
NC score	0.174996 (rank : 329)	θ value	0.813845 (rank : 417)
Query Neighborhood Hits	613	Target Neighborhood Hits	584	Shared Neighborhood Hits	240
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

TNR1A_MOUSE
NC score	0.174865 (rank : 330)	θ value	0.0736092 (rank : 301)
Query Neighborhood Hits	613	Target Neighborhood Hits	131	Shared Neighborhood Hits	93
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

LCE2A_HUMAN
NC score	0.174405 (rank : 331)	θ value	1.06291 (rank : 435)
Query Neighborhood Hits	613	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2C_HUMAN
NC score	0.174211 (rank : 332)	θ value	4.03905 (rank : 527)
Query Neighborhood Hits	613	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LRP6_MOUSE
NC score	0.174163 (rank : 333)	θ value	8.99809 (rank : 601)
Query Neighborhood Hits	613	Target Neighborhood Hits	232	Shared Neighborhood Hits	135
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MT1X_HUMAN
NC score	0.173146 (rank : 334)	θ value	0.279714 (rank : 357)
Query Neighborhood Hits	613	Target Neighborhood Hits	76	Shared Neighborhood Hits	68
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

CRAC1_MOUSE
NC score	0.172402 (rank : 335)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	613	Target Neighborhood Hits	112	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

TNR4_HUMAN
NC score	0.172128 (rank : 336)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	613	Target Neighborhood Hits	152	Shared Neighborhood Hits	106
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

MT1A_HUMAN
NC score	0.172076 (rank : 337)	θ value	0.279714 (rank : 355)
Query Neighborhood Hits	613	Target Neighborhood Hits	74	Shared Neighborhood Hits	61
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

LCE2D_HUMAN
NC score	0.171638 (rank : 338)	θ value	2.36792 (rank : 481)
Query Neighborhood Hits	613	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LRP5_MOUSE
NC score	0.171218 (rank : 339)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	613	Target Neighborhood Hits	236	Shared Neighborhood Hits	138
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

CRAC1_HUMAN
NC score	0.170149 (rank : 340)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	613	Target Neighborhood Hits	111	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

TIE1_HUMAN
NC score	0.168821 (rank : 341)	θ value	3.77169e-06 (rank : 124)
Query Neighborhood Hits	613	Target Neighborhood Hits	1241	Shared Neighborhood Hits	250
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

MFGM_MOUSE
NC score	0.168668 (rank : 342)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	613	Target Neighborhood Hits	233	Shared Neighborhood Hits	140
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

CFC1_MOUSE
NC score	0.168650 (rank : 343)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	613	Target Neighborhood Hits	125	Shared Neighborhood Hits	92
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

TNR5_MOUSE
NC score	0.168609 (rank : 344)	θ value	0.813845 (rank : 425)
Query Neighborhood Hits	613	Target Neighborhood Hits	131	Shared Neighborhood Hits	106
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

ELTD1_HUMAN
NC score	0.168343 (rank : 345)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	613	Target Neighborhood Hits	269	Shared Neighborhood Hits	156
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

MT1_MOUSE
NC score	0.167188 (rank : 346)	θ value	0.0330416 (rank : 273)
Query Neighborhood Hits	613	Target Neighborhood Hits	72	Shared Neighborhood Hits	58
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

LRP5_HUMAN
NC score	0.166481 (rank : 347)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	613	Target Neighborhood Hits	224	Shared Neighborhood Hits	132
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

TNR1A_HUMAN
NC score	0.165577 (rank : 348)	θ value	0.000786445 (rank : 187)
Query Neighborhood Hits	613	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TEFF2_MOUSE
NC score	0.164755 (rank : 349)	θ value	1.81305 (rank : 464)
Query Neighborhood Hits	613	Target Neighborhood Hits	214	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TIE1_MOUSE
NC score	0.163636 (rank : 350)	θ value	1.69304e-06 (rank : 114)
Query Neighborhood Hits	613	Target Neighborhood Hits	1266	Shared Neighborhood Hits	252
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

LCE2B_HUMAN
NC score	0.163242 (rank : 351)	θ value	6.88961 (rank : 577)
Query Neighborhood Hits	613	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

TEFF2_HUMAN
NC score	0.162944 (rank : 352)	θ value	1.81305 (rank : 463)
Query Neighborhood Hits	613	Target Neighborhood Hits	211	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

WFDC3_HUMAN
NC score	0.162929 (rank : 353)	θ value	0.47712 (rank : 393)
Query Neighborhood Hits	613	Target Neighborhood Hits	138	Shared Neighborhood Hits	92
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

RECK_HUMAN
NC score	0.162621 (rank : 354)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	613	Target Neighborhood Hits	189	Shared Neighborhood Hits	114
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

CT127_HUMAN
NC score	0.161286 (rank : 355)	θ value	0.279714 (rank : 348)
Query Neighborhood Hits	613	Target Neighborhood Hits	67	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

MT1L_HUMAN
NC score	0.160479 (rank : 356)	θ value	0.0252991 (rank : 265)
Query Neighborhood Hits	613	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT1H_HUMAN
NC score	0.160267 (rank : 357)	θ value	0.47712 (rank : 386)
Query Neighborhood Hits	613	Target Neighborhood Hits	78	Shared Neighborhood Hits	67
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

KR413_HUMAN
NC score	0.159813 (rank : 358)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	613	Target Neighborhood Hits	112	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

MT1B_HUMAN
NC score	0.158149 (rank : 359)	θ value	0.365318 (rank : 370)
Query Neighborhood Hits	613	Target Neighborhood Hits	87	Shared Neighborhood Hits	71
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

TNR1B_HUMAN
NC score	0.157803 (rank : 360)	θ value	0.0148317 (rank : 249)
Query Neighborhood Hits	613	Target Neighborhood Hits	127	Shared Neighborhood Hits	92
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR3_HUMAN
NC score	0.157251 (rank : 361)	θ value	0.0252991 (rank : 268)
Query Neighborhood Hits	613	Target Neighborhood Hits	145	Shared Neighborhood Hits	87
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR8_HUMAN
NC score	0.157067 (rank : 362)	θ value	0.62314 (rank : 409)
Query Neighborhood Hits	613	Target Neighborhood Hits	198	Shared Neighborhood Hits	114
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

LYAM1_MOUSE
NC score	0.155067 (rank : 363)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	613	Target Neighborhood Hits	332	Shared Neighborhood Hits	165
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

ESM1_HUMAN
NC score	0.155022 (rank : 364)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	613	Target Neighborhood Hits	110	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

TIE2_MOUSE
NC score	0.154744 (rank : 365)	θ value	5.44631e-05 (rank : 147)
Query Neighborhood Hits	613	Target Neighborhood Hits	1204	Shared Neighborhood Hits	247
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

PERT_HUMAN
NC score	0.154258 (rank : 366)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	613	Target Neighborhood Hits	221	Shared Neighborhood Hits	139
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

TNR1B_MOUSE
NC score	0.153583 (rank : 367)	θ value	0.0113563 (rank : 239)
Query Neighborhood Hits	613	Target Neighborhood Hits	123	Shared Neighborhood Hits	82
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR6B_HUMAN
NC score	0.153094 (rank : 368)	θ value	1.06291 (rank : 440)
Query Neighborhood Hits	613	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR6_MOUSE
NC score	0.152163 (rank : 369)	θ value	1.81305 (rank : 467)
Query Neighborhood Hits	613	Target Neighborhood Hits	99	Shared Neighborhood Hits	88
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_MOUSE
NC score	0.150554 (rank : 370)	θ value	0.0563607 (rank : 295)
Query Neighborhood Hits	613	Target Neighborhood Hits	112	Shared Neighborhood Hits	88
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

LCE5A_HUMAN
NC score	0.149628 (rank : 371)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	613	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

BMP1_MOUSE
NC score	0.149565 (rank : 372)	θ value	1.81305 (rank : 460)
Query Neighborhood Hits	613	Target Neighborhood Hits	236	Shared Neighborhood Hits	141
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_HUMAN
NC score	0.148686 (rank : 373)	θ value	1.81305 (rank : 459)
Query Neighborhood Hits	613	Target Neighborhood Hits	233	Shared Neighborhood Hits	140
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TNR3_MOUSE
NC score	0.147505 (rank : 374)	θ value	0.62314 (rank : 407)
Query Neighborhood Hits	613	Target Neighborhood Hits	113	Shared Neighborhood Hits	93
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR11_HUMAN
NC score	0.147148 (rank : 375)	θ value	6.88961 (rank : 580)
Query Neighborhood Hits	613	Target Neighborhood Hits	135	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TIE2_HUMAN
NC score	0.146724 (rank : 376)	θ value	0.0113563 (rank : 238)
Query Neighborhood Hits	613	Target Neighborhood Hits	1192	Shared Neighborhood Hits	237
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

LYAM1_HUMAN
NC score	0.146609 (rank : 377)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	613	Target Neighborhood Hits	315	Shared Neighborhood Hits	162
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

UROL1_MOUSE
NC score	0.146604 (rank : 378)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	613	Target Neighborhood Hits	235	Shared Neighborhood Hits	122
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

RECK_MOUSE
NC score	0.146014 (rank : 379)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	613	Target Neighborhood Hits	158	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TDGF1_HUMAN
NC score	0.145722 (rank : 380)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	613	Target Neighborhood Hits	132	Shared Neighborhood Hits	91
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF2_HUMAN
NC score	0.145537 (rank : 381)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	613	Target Neighborhood Hits	131	Shared Neighborhood Hits	88
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

PERT_MOUSE
NC score	0.144790 (rank : 382)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	613	Target Neighborhood Hits	221	Shared Neighborhood Hits	132
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MT1G_HUMAN
NC score	0.144376 (rank : 383)	θ value	0.163984 (rank : 324)
Query Neighborhood Hits	613	Target Neighborhood Hits	63	Shared Neighborhood Hits	54
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

MT1E_HUMAN
NC score	0.143032 (rank : 384)	θ value	0.125558 (rank : 311)
Query Neighborhood Hits	613	Target Neighborhood Hits	75	Shared Neighborhood Hits	66
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MATN1_MOUSE
NC score	0.142620 (rank : 385)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	613	Target Neighborhood Hits	186	Shared Neighborhood Hits	111
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

FST_MOUSE
NC score	0.142561 (rank : 386)	θ value	0.0148317 (rank : 245)
Query Neighborhood Hits	613	Target Neighborhood Hits	146	Shared Neighborhood Hits	85
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

MATN1_HUMAN
NC score	0.142376 (rank : 387)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	613	Target Neighborhood Hits	191	Shared Neighborhood Hits	113
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

TLL1_MOUSE
NC score	0.142375 (rank : 388)	θ value	3.0926 (rank : 514)
Query Neighborhood Hits	613	Target Neighborhood Hits	237	Shared Neighborhood Hits	140
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

LCE4A_HUMAN
NC score	0.141821 (rank : 389)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	613	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

MUC13_MOUSE
NC score	0.141696 (rank : 390)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	613	Target Neighborhood Hits	447	Shared Neighborhood Hits	148
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

LRP3_HUMAN
NC score	0.141002 (rank : 391)	θ value	0.21417 (rank : 339)
Query Neighborhood Hits	613	Target Neighborhood Hits	280	Shared Neighborhood Hits	121
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

TR11B_HUMAN
NC score	0.140978 (rank : 392)	θ value	0.00134147 (rank : 197)
Query Neighborhood Hits	613	Target Neighborhood Hits	92	Shared Neighborhood Hits	73
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

MT1F_HUMAN
NC score	0.140886 (rank : 393)	θ value	0.279714 (rank : 356)
Query Neighborhood Hits	613	Target Neighborhood Hits	73	Shared Neighborhood Hits	64
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

UROL1_HUMAN
NC score	0.139590 (rank : 394)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	613	Target Neighborhood Hits	213	Shared Neighborhood Hits	116
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

TLL2_MOUSE
NC score	0.139379 (rank : 395)	θ value	1.81305 (rank : 465)
Query Neighborhood Hits	613	Target Neighborhood Hits	240	Shared Neighborhood Hits	139
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_HUMAN
NC score	0.139356 (rank : 396)	θ value	2.36792 (rank : 488)
Query Neighborhood Hits	613	Target Neighborhood Hits	236	Shared Neighborhood Hits	137
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

HABP2_HUMAN
NC score	0.139295 (rank : 397)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	613	Target Neighborhood Hits	431	Shared Neighborhood Hits	194
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

MT2_HUMAN
NC score	0.138728 (rank : 398)	θ value	0.125558 (rank : 312)
Query Neighborhood Hits	613	Target Neighborhood Hits	69	Shared Neighborhood Hits	63
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

VEGFC_HUMAN
NC score	0.137936 (rank : 399)	θ value	0.0563607 (rank : 296)
Query Neighborhood Hits	613	Target Neighborhood Hits	128	Shared Neighborhood Hits	98
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

TLL2_HUMAN
NC score	0.137520 (rank : 400)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	613	Target Neighborhood Hits	241	Shared Neighborhood Hits	143
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CLC14_MOUSE
NC score	0.137325 (rank : 401)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	613	Target Neighborhood Hits	120	Shared Neighborhood Hits	89
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

TNR11_MOUSE
NC score	0.136301 (rank : 402)	θ value	8.99809 (rank : 604)
Query Neighborhood Hits	613	Target Neighborhood Hits	121	Shared Neighborhood Hits	95
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR5_HUMAN
NC score	0.136217 (rank : 403)	θ value	0.62314 (rank : 408)
Query Neighborhood Hits	613	Target Neighborhood Hits	102	Shared Neighborhood Hits	92
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

ADA11_MOUSE
NC score	0.136163 (rank : 404)	θ value	0.21417 (rank : 332)
Query Neighborhood Hits	613	Target Neighborhood Hits	263	Shared Neighborhood Hits	184
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

HABP2_MOUSE
NC score	0.135893 (rank : 405)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	613	Target Neighborhood Hits	445	Shared Neighborhood Hits	197
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

ADA11_HUMAN
NC score	0.135204 (rank : 406)	θ value	0.279714 (rank : 345)
Query Neighborhood Hits	613	Target Neighborhood Hits	259	Shared Neighborhood Hits	184
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ESM1_MOUSE
NC score	0.134687 (rank : 407)	θ value	6.88961 (rank : 574)
Query Neighborhood Hits	613	Target Neighborhood Hits	107	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

TNR8_MOUSE
NC score	0.134648 (rank : 408)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	613	Target Neighborhood Hits	208	Shared Neighborhood Hits	109
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

LRP10_MOUSE
NC score	0.134065 (rank : 409)	θ value	0.365318 (rank : 369)
Query Neighborhood Hits	613	Target Neighborhood Hits	169	Shared Neighborhood Hits	90
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

MKS3_MOUSE
NC score	0.133590 (rank : 410)	θ value	1.38821 (rank : 454)
Query Neighborhood Hits	613	Target Neighborhood Hits	89	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

TNR6_HUMAN
NC score	0.133426 (rank : 411)	θ value	1.81305 (rank : 466)
Query Neighborhood Hits	613	Target Neighborhood Hits	95	Shared Neighborhood Hits	78
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

MCSP_MOUSE
NC score	0.133242 (rank : 412)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	613	Target Neighborhood Hits	108	Shared Neighborhood Hits	56
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

LRP10_HUMAN
NC score	0.132608 (rank : 413)	θ value	0.365318 (rank : 368)
Query Neighborhood Hits	613	Target Neighborhood Hits	197	Shared Neighborhood Hits	93
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

ADAM8_MOUSE
NC score	0.132233 (rank : 414)	θ value	0.62314 (rank : 398)
Query Neighborhood Hits	613	Target Neighborhood Hits	326	Shared Neighborhood Hits	190
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

EMR3_HUMAN
NC score	0.131997 (rank : 415)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	613	Target Neighborhood Hits	245	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

CO6_HUMAN
NC score	0.129938 (rank : 416)	θ value	5.27518 (rank : 545)
Query Neighborhood Hits	613	Target Neighborhood Hits	331	Shared Neighborhood Hits	168
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

ADAM8_HUMAN
NC score	0.129643 (rank : 417)	θ value	4.03905 (rank : 519)
Query Neighborhood Hits	613	Target Neighborhood Hits	327	Shared Neighborhood Hits	199
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADA15_MOUSE
NC score	0.129573 (rank : 418)	θ value	0.813845 (rank : 414)
Query Neighborhood Hits	613	Target Neighborhood Hits	324	Shared Neighborhood Hits	196
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

TNR19_MOUSE
NC score	0.128925 (rank : 419)	θ value	0.125558 (rank : 316)
Query Neighborhood Hits	613	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

ADA19_MOUSE
NC score	0.128852 (rank : 420)	θ value	0.00102713 (rank : 188)
Query Neighborhood Hits	613	Target Neighborhood Hits	315	Shared Neighborhood Hits	184
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA15_HUMAN
NC score	0.128673 (rank : 421)	θ value	0.0431538 (rank : 278)
Query Neighborhood Hits	613	Target Neighborhood Hits	288	Shared Neighborhood Hits	186
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

TR10C_HUMAN
NC score	0.128573 (rank : 422)	θ value	0.0736092 (rank : 302)
Query Neighborhood Hits	613	Target Neighborhood Hits	105	Shared Neighborhood Hits	60
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

CORIN_HUMAN
NC score	0.128088 (rank : 423)	θ value	0.00665767 (rank : 224)
Query Neighborhood Hits	613	Target Neighborhood Hits	453	Shared Neighborhood Hits	189
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

FST_HUMAN
NC score	0.127759 (rank : 424)	θ value	0.0330416 (rank : 272)
Query Neighborhood Hits	613	Target Neighborhood Hits	129	Shared Neighborhood Hits	68
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

TR11B_MOUSE
NC score	0.127509 (rank : 425)	θ value	0.0330416 (rank : 275)
Query Neighborhood Hits	613	Target Neighborhood Hits	95	Shared Neighborhood Hits	76
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

CLC14_HUMAN
NC score	0.127333 (rank : 426)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	613	Target Neighborhood Hits	143	Shared Neighborhood Hits	95
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

TNR21_HUMAN
NC score	0.126813 (rank : 427)	θ value	0.0148317 (rank : 250)
Query Neighborhood Hits	613	Target Neighborhood Hits	90	Shared Neighborhood Hits	74
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

KR124_HUMAN
NC score	0.126541 (rank : 428)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	613	Target Neighborhood Hits	124	Shared Neighborhood Hits	89
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

CHRD_HUMAN
NC score	0.126240 (rank : 429)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	613	Target Neighborhood Hits	102	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

MT1I_HUMAN
NC score	0.125530 (rank : 430)	θ value	0.47712 (rank : 387)
Query Neighborhood Hits	613	Target Neighborhood Hits	64	Shared Neighborhood Hits	56
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

FSTL3_HUMAN
NC score	0.125200 (rank : 431)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	613	Target Neighborhood Hits	162	Shared Neighborhood Hits	102
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

ADA17_HUMAN
NC score	0.124910 (rank : 432)	θ value	5.27518 (rank : 540)
Query Neighborhood Hits	613	Target Neighborhood Hits	223	Shared Neighborhood Hits	154
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

FA10_MOUSE
NC score	0.124301 (rank : 433)	θ value	6.88961 (rank : 575)
Query Neighborhood Hits	613	Target Neighborhood Hits	435	Shared Neighborhood Hits	194
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

PROC_MOUSE
NC score	0.123181 (rank : 434)	θ value	6.88961 (rank : 579)
Query Neighborhood Hits	613	Target Neighborhood Hits	426	Shared Neighborhood Hits	202
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

RELN_MOUSE
NC score	0.122977 (rank : 435)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	613	Target Neighborhood Hits	235	Shared Neighborhood Hits	149
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

CHRD_MOUSE
NC score	0.122627 (rank : 436)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	613	Target Neighborhood Hits	102	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

FA10_HUMAN
NC score	0.122307 (rank : 437)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	613	Target Neighborhood Hits	431	Shared Neighborhood Hits	195
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

TNR21_MOUSE
NC score	0.122298 (rank : 438)	θ value	0.163984 (rank : 329)
Query Neighborhood Hits	613	Target Neighborhood Hits	108	Shared Neighborhood Hits	75
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

KR122_HUMAN
NC score	0.122012 (rank : 439)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	613	Target Neighborhood Hits	97	Shared Neighborhood Hits	66
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

TNR19_HUMAN
NC score	0.121970 (rank : 440)	θ value	0.0431538 (rank : 285)
Query Neighborhood Hits	613	Target Neighborhood Hits	89	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TR10A_HUMAN
NC score	0.121861 (rank : 441)	θ value	0.365318 (rank : 375)
Query Neighborhood Hits	613	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

CD320_HUMAN
NC score	0.121227 (rank : 442)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	613	Target Neighborhood Hits	103	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

FSTL3_MOUSE
NC score	0.119588 (rank : 443)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	613	Target Neighborhood Hits	152	Shared Neighborhood Hits	98
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

ADA23_HUMAN
NC score	0.119558 (rank : 444)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	613	Target Neighborhood Hits	235	Shared Neighborhood Hits	162
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ERBB3_HUMAN
NC score	0.119184 (rank : 445)	θ value	1.74796e-11 (rank : 46)
Query Neighborhood Hits	613	Target Neighborhood Hits	918	Shared Neighborhood Hits	124
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

RELN_HUMAN
NC score	0.119077 (rank : 446)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	613	Target Neighborhood Hits	233	Shared Neighborhood Hits	148
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

ADA23_MOUSE
NC score	0.118958 (rank : 447)	θ value	5.27518 (rank : 541)
Query Neighborhood Hits	613	Target Neighborhood Hits	245	Shared Neighborhood Hits	175
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA19_HUMAN
NC score	0.117760 (rank : 448)	θ value	0.47712 (rank : 380)
Query Neighborhood Hits	613	Target Neighborhood Hits	381	Shared Neighborhood Hits	167
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

TR10B_MOUSE
NC score	0.117621 (rank : 449)	θ value	0.21417 (rank : 340)
Query Neighborhood Hits	613	Target Neighborhood Hits	76	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

MKS3_HUMAN
NC score	0.117284 (rank : 450)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	613	Target Neighborhood Hits	79	Shared Neighborhood Hits	71
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

PHXR5_MOUSE
NC score	0.117122 (rank : 451)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	613	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

VEGFC_MOUSE
NC score	0.116354 (rank : 452)	θ value	0.125558 (rank : 319)
Query Neighborhood Hits	613	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CORIN_MOUSE
NC score	0.116063 (rank : 453)	θ value	0.00175202 (rank : 198)
Query Neighborhood Hits	613	Target Neighborhood Hits	451	Shared Neighborhood Hits	185
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

TR10B_HUMAN
NC score	0.116054 (rank : 454)	θ value	0.0252991 (rank : 269)
Query Neighborhood Hits	613	Target Neighborhood Hits	71	Shared Neighborhood Hits	60
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

ERBB3_MOUSE
NC score	0.115391 (rank : 455)	θ value	1.9326e-10 (rank : 58)
Query Neighborhood Hits	613	Target Neighborhood Hits	898	Shared Neighborhood Hits	108
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ADA33_HUMAN
NC score	0.114616 (rank : 456)	θ value	1.38821 (rank : 445)
Query Neighborhood Hits	613	Target Neighborhood Hits	264	Shared Neighborhood Hits	159
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

FA9_HUMAN
NC score	0.114094 (rank : 457)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	613	Target Neighborhood Hits	421	Shared Neighborhood Hits	181
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

ADA22_MOUSE
NC score	0.114061 (rank : 458)	θ value	0.0330416 (rank : 270)
Query Neighborhood Hits	613	Target Neighborhood Hits	225	Shared Neighborhood Hits	152
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

NRX1A_HUMAN
NC score	0.113637 (rank : 459)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	613	Target Neighborhood Hits	170	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

CO7_HUMAN
NC score	0.113514 (rank : 460)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	613	Target Neighborhood Hits	278	Shared Neighborhood Hits	146
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

ADAM9_MOUSE
NC score	0.113325 (rank : 461)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	613	Target Neighborhood Hits	325	Shared Neighborhood Hits	193
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

MT1M_HUMAN
NC score	0.112860 (rank : 462)	θ value	2.36792 (rank : 483)
Query Neighborhood Hits	613	Target Neighborhood Hits	72	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

NRX1A_MOUSE
NC score	0.112563 (rank : 463)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	613	Target Neighborhood Hits	164	Shared Neighborhood Hits	92
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

ADA33_MOUSE
NC score	0.112260 (rank : 464)	θ value	0.47712 (rank : 381)
Query Neighborhood Hits	613	Target Neighborhood Hits	231	Shared Neighborhood Hits	160
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA18_MOUSE
NC score	0.112177 (rank : 465)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	613	Target Neighborhood Hits	227	Shared Neighborhood Hits	170
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

TR10D_HUMAN
NC score	0.110908 (rank : 466)	θ value	0.00509761 (rank : 221)
Query Neighborhood Hits	613	Target Neighborhood Hits	62	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

ADAM7_HUMAN
NC score	0.110346 (rank : 467)	θ value	1.06291 (rank : 430)
Query Neighborhood Hits	613	Target Neighborhood Hits	221	Shared Neighborhood Hits	165
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADA22_HUMAN
NC score	0.108314 (rank : 468)	θ value	0.0193708 (rank : 251)
Query Neighborhood Hits	613	Target Neighborhood Hits	211	Shared Neighborhood Hits	145
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADAM9_HUMAN
NC score	0.107987 (rank : 469)	θ value	3.0926 (rank : 496)
Query Neighborhood Hits	613	Target Neighborhood Hits	243	Shared Neighborhood Hits	171
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADA12_HUMAN
NC score	0.107767 (rank : 470)	θ value	0.21417 (rank : 333)
Query Neighborhood Hits	613	Target Neighborhood Hits	224	Shared Neighborhood Hits	140
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

INSRR_MOUSE
NC score	0.107542 (rank : 471)	θ value	2.88788e-06 (rank : 117)
Query Neighborhood Hits	613	Target Neighborhood Hits	961	Shared Neighborhood Hits	147
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

ADA10_HUMAN
NC score	0.107478 (rank : 472)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	613	Target Neighborhood Hits	189	Shared Neighborhood Hits	132
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

INSRR_HUMAN
NC score	0.106949 (rank : 473)	θ value	2.21117e-06 (rank : 115)
Query Neighborhood Hits	613	Target Neighborhood Hits	950	Shared Neighborhood Hits	133
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

NRX3A_HUMAN
NC score	0.106576 (rank : 474)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	613	Target Neighborhood Hits	164	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PROC_HUMAN
NC score	0.106553 (rank : 475)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	613	Target Neighborhood Hits	406	Shared Neighborhood Hits	192
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

ERBB4_HUMAN
NC score	0.105745 (rank : 476)	θ value	3.52202e-12 (rank : 42)
Query Neighborhood Hits	613	Target Neighborhood Hits	910	Shared Neighborhood Hits	103
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

ADM1A_MOUSE
NC score	0.105175 (rank : 477)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	613	Target Neighborhood Hits	230	Shared Neighborhood Hits	167
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

FA7_HUMAN
NC score	0.105160 (rank : 478)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	613	Target Neighborhood Hits	404	Shared Neighborhood Hits	179
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

ADA10_MOUSE
NC score	0.105159 (rank : 479)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	613	Target Neighborhood Hits	194	Shared Neighborhood Hits	128
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

LRP12_HUMAN
NC score	0.104043 (rank : 480)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	613	Target Neighborhood Hits	205	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

ADA28_HUMAN
NC score	0.103297 (rank : 481)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	613	Target Neighborhood Hits	244	Shared Neighborhood Hits	172
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

HGFA_MOUSE
NC score	0.103232 (rank : 482)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	613	Target Neighborhood Hits	419	Shared Neighborhood Hits	172
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_HUMAN
NC score	0.103197 (rank : 483)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	613	Target Neighborhood Hits	436	Shared Neighborhood Hits	170
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LRP12_MOUSE
NC score	0.102582 (rank : 484)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	613	Target Neighborhood Hits	180	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

FAT2_HUMAN
NC score	0.102263 (rank : 485)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	613	Target Neighborhood Hits	507	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

ADA18_HUMAN
NC score	0.101953 (rank : 486)	θ value	0.125558 (rank : 306)
Query Neighborhood Hits	613	Target Neighborhood Hits	184	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADAM2_MOUSE
NC score	0.101945 (rank : 487)	θ value	0.279714 (rank : 346)
Query Neighborhood Hits	613	Target Neighborhood Hits	209	Shared Neighborhood Hits	135
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

CO8B_MOUSE
NC score	0.101780 (rank : 488)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	613	Target Neighborhood Hits	224	Shared Neighborhood Hits	122
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

IGF1R_MOUSE
NC score	0.101754 (rank : 489)	θ value	2.36244e-08 (rank : 82)
Query Neighborhood Hits	613	Target Neighborhood Hits	973	Shared Neighborhood Hits	145
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

NRX2A_HUMAN
NC score	0.101691 (rank : 490)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	613	Target Neighborhood Hits	614	Shared Neighborhood Hits	100
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

CRDL2_MOUSE
NC score	0.101588 (rank : 491)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	613	Target Neighborhood Hits	81	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

LORI_MOUSE
NC score	0.100755 (rank : 492)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	613	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

ADA12_MOUSE
NC score	0.100707 (rank : 493)	θ value	0.813845 (rank : 413)
Query Neighborhood Hits	613	Target Neighborhood Hits	474	Shared Neighborhood Hits	128
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ERBB2_HUMAN
NC score	0.100612 (rank : 494)	θ value	8.11959e-09 (rank : 76)
Query Neighborhood Hits	613	Target Neighborhood Hits	1073	Shared Neighborhood Hits	104
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

PAPPA_HUMAN
NC score	0.100352 (rank : 495)	θ value	0.0736092 (rank : 300)
Query Neighborhood Hits	613	Target Neighborhood Hits	161	Shared Neighborhood Hits	81
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

ERBB2_MOUSE
NC score	0.100063 (rank : 496)	θ value	1.47974e-10 (rank : 57)
Query Neighborhood Hits	613	Target Neighborhood Hits	918	Shared Neighborhood Hits	91
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

KR111_HUMAN
NC score	0.099750 (rank : 497)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	613	Target Neighborhood Hits	90	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

EGFR_HUMAN
NC score	0.099564 (rank : 498)	θ value	2.13673e-09 (rank : 70)
Query Neighborhood Hits	613	Target Neighborhood Hits	939	Shared Neighborhood Hits	116
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

ADM1B_MOUSE
NC score	0.099143 (rank : 499)	θ value	0.365318 (rank : 364)
Query Neighborhood Hits	613	Target Neighborhood Hits	236	Shared Neighborhood Hits	144
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA28_MOUSE
NC score	0.099074 (rank : 500)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	613	Target Neighborhood Hits	241	Shared Neighborhood Hits	162
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

EGFR_MOUSE
NC score	0.098889 (rank : 501)	θ value	4.45536e-07 (rank : 101)
Query Neighborhood Hits	613	Target Neighborhood Hits	927	Shared Neighborhood Hits	112
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

IGF1R_HUMAN
NC score	0.098759 (rank : 502)	θ value	1.53129e-07 (rank : 92)
Query Neighborhood Hits	613	Target Neighborhood Hits	977	Shared Neighborhood Hits	147
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KR123_HUMAN
NC score	0.098210 (rank : 503)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	613	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

CRDL2_HUMAN
NC score	0.097961 (rank : 504)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	613	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

PGCB_MOUSE
NC score	0.097732 (rank : 505)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	613	Target Neighborhood Hits	459	Shared Neighborhood Hits	140
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

ADA17_MOUSE
NC score	0.097667 (rank : 506)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	613	Target Neighborhood Hits	201	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ASTN_HUMAN
NC score	0.097328 (rank : 507)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	613	Target Neighborhood Hits	105	Shared Neighborhood Hits	76
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

INSR_HUMAN
NC score	0.096566 (rank : 508)	θ value	3.77169e-06 (rank : 121)
Query Neighborhood Hits	613	Target Neighborhood Hits	963	Shared Neighborhood Hits	129
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

ASTN_MOUSE
NC score	0.096444 (rank : 509)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	613	Target Neighborhood Hits	98	Shared Neighborhood Hits	73
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

CNTP2_MOUSE
NC score	0.096391 (rank : 510)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	613	Target Neighborhood Hits	194	Shared Neighborhood Hits	100
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

PAPPA_MOUSE
NC score	0.096105 (rank : 511)	θ value	2.36792 (rank : 484)
Query Neighborhood Hits	613	Target Neighborhood Hits	153	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

INSR_MOUSE
NC score	0.095443 (rank : 512)	θ value	4.45536e-07 (rank : 102)
Query Neighborhood Hits	613	Target Neighborhood Hits	968	Shared Neighborhood Hits	122
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

CNTP2_HUMAN
NC score	0.095214 (rank : 513)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	613	Target Neighborhood Hits	199	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

ADA32_HUMAN
NC score	0.095204 (rank : 514)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	613	Target Neighborhood Hits	216	Shared Neighborhood Hits	145
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

EMR4_MOUSE
NC score	0.094735 (rank : 515)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	613	Target Neighborhood Hits	191	Shared Neighborhood Hits	102
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

SPR2D_MOUSE
NC score	0.094170 (rank : 516)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	613	Target Neighborhood Hits	61	Shared Neighborhood Hits	23
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

PROP_MOUSE
NC score	0.094093 (rank : 517)	θ value	0.163984 (rank : 326)
Query Neighborhood Hits	613	Target Neighborhood Hits	165	Shared Neighborhood Hits	65
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

FA12_HUMAN
NC score	0.093355 (rank : 518)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	613	Target Neighborhood Hits	425	Shared Neighborhood Hits	164
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

SPR2G_MOUSE
NC score	0.092684 (rank : 519)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	613	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

ADAM7_MOUSE
NC score	0.092518 (rank : 520)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	613	Target Neighborhood Hits	200	Shared Neighborhood Hits	144
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADA30_HUMAN
NC score	0.092287 (rank : 521)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	613	Target Neighborhood Hits	391	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

FREM2_MOUSE
NC score	0.091732 (rank : 522)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	613	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

ADA25_MOUSE
NC score	0.091645 (rank : 523)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	613	Target Neighborhood Hits	213	Shared Neighborhood Hits	146
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

PGCB_HUMAN
NC score	0.091186 (rank : 524)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	613	Target Neighborhood Hits	478	Shared Neighborhood Hits	137
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

ADA24_MOUSE
NC score	0.091000 (rank : 525)	θ value	4.03905 (rank : 518)
Query Neighborhood Hits	613	Target Neighborhood Hits	230	Shared Neighborhood Hits	160
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

FREM2_HUMAN
NC score	0.090632 (rank : 526)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	613	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

CNTP4_MOUSE
NC score	0.090413 (rank : 527)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	613	Target Neighborhood Hits	193	Shared Neighborhood Hits	99
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

ST14_HUMAN
NC score	0.089768 (rank : 528)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	613	Target Neighborhood Hits	409	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

KR131_HUMAN
NC score	0.089565 (rank : 529)	θ value	0.279714 (rank : 352)
Query Neighborhood Hits	613	Target Neighborhood Hits	123	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

ADAM2_HUMAN
NC score	0.089307 (rank : 530)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	613	Target Neighborhood Hits	175	Shared Neighborhood Hits	121
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADA21_MOUSE
NC score	0.089047 (rank : 531)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	613	Target Neighborhood Hits	172	Shared Neighborhood Hits	119
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

CNTP4_HUMAN
NC score	0.088884 (rank : 532)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	613	Target Neighborhood Hits	187	Shared Neighborhood Hits	89
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

ST14_MOUSE
NC score	0.088868 (rank : 533)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	613	Target Neighborhood Hits	419	Shared Neighborhood Hits	171
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ADA21_HUMAN
NC score	0.088776 (rank : 534)	θ value	1.38821 (rank : 444)
Query Neighborhood Hits	613	Target Neighborhood Hits	181	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA32_MOUSE
NC score	0.088086 (rank : 535)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	613	Target Neighborhood Hits	219	Shared Neighborhood Hits	149
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

CRDL1_HUMAN
NC score	0.087936 (rank : 536)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	613	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_MOUSE
NC score	0.087882 (rank : 537)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	613	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

ADA29_HUMAN
NC score	0.086631 (rank : 538)	θ value	0.0193708 (rank : 252)
Query Neighborhood Hits	613	Target Neighborhood Hits	247	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

MUC13_HUMAN
NC score	0.086105 (rank : 539)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	613	Target Neighborhood Hits	164	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

CSPG4_HUMAN
NC score	0.085015 (rank : 540)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	613	Target Neighborhood Hits	112	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

PGCA_HUMAN
NC score	0.083459 (rank : 541)	θ value	6.88961 (rank : 578)
Query Neighborhood Hits	613	Target Neighborhood Hits	821	Shared Neighborhood Hits	148
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

LCE3B_HUMAN
NC score	0.082734 (rank : 542)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	613	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

MMRN1_HUMAN
NC score	0.082390 (rank : 543)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	613	Target Neighborhood Hits	636	Shared Neighborhood Hits	108
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

SPR2H_MOUSE
NC score	0.082337 (rank : 544)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	613	Target Neighborhood Hits	82	Shared Neighborhood Hits	28
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

NRG4_HUMAN
NC score	0.082322 (rank : 545)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	613	Target Neighborhood Hits	85	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

CO8A_HUMAN
NC score	0.082210 (rank : 546)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	613	Target Neighborhood Hits	200	Shared Neighborhood Hits	113
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

FA7_MOUSE
NC score	0.082133 (rank : 547)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	613	Target Neighborhood Hits	374	Shared Neighborhood Hits	155
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

CNTP3_HUMAN
NC score	0.082126 (rank : 548)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	613	Target Neighborhood Hits	195	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CSPG4_MOUSE
NC score	0.081926 (rank : 549)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	613	Target Neighborhood Hits	105	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CO8B_HUMAN
NC score	0.081790 (rank : 550)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	613	Target Neighborhood Hits	199	Shared Neighborhood Hits	102
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

TNR27_MOUSE
NC score	0.081757 (rank : 551)	θ value	0.163984 (rank : 330)
Query Neighborhood Hits	613	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

KR241_HUMAN
NC score	0.081321 (rank : 552)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	613	Target Neighborhood Hits	71	Shared Neighborhood Hits	52
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

FREM3_HUMAN
NC score	0.079634 (rank : 553)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	613	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

FREM3_MOUSE
NC score	0.079506 (rank : 554)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	613	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

PROP_HUMAN
NC score	0.078597 (rank : 555)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	613	Target Neighborhood Hits	126	Shared Neighborhood Hits	56
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

SMDF_HUMAN
NC score	0.078409 (rank : 556)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	613	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

CNTP1_HUMAN
NC score	0.078163 (rank : 557)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	613	Target Neighborhood Hits	196	Shared Neighborhood Hits	89
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

MEP1A_MOUSE
NC score	0.077808 (rank : 558)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	613	Target Neighborhood Hits	166	Shared Neighborhood Hits	99
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

NRG1_HUMAN
NC score	0.077707 (rank : 559)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	613	Target Neighborhood Hits	285	Shared Neighborhood Hits	73
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

CO8A_MOUSE
NC score	0.077563 (rank : 560)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	613	Target Neighborhood Hits	182	Shared Neighborhood Hits	93
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

APR3_MOUSE
NC score	0.076349 (rank : 561)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	613	Target Neighborhood Hits	61	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

KR261_HUMAN
NC score	0.076045 (rank : 562)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	613	Target Neighborhood Hits	65	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

MEP1A_HUMAN
NC score	0.075976 (rank : 563)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	613	Target Neighborhood Hits	162	Shared Neighborhood Hits	100
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

CO9_MOUSE
NC score	0.075801 (rank : 564)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	613	Target Neighborhood Hits	153	Shared Neighborhood Hits	79
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CNTP1_MOUSE
NC score	0.075579 (rank : 565)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	613	Target Neighborhood Hits	183	Shared Neighborhood Hits	81
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

PAP2_HUMAN
NC score	0.075479 (rank : 566)	θ value	0.0736092 (rank : 299)
Query Neighborhood Hits	613	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

C1RA_MOUSE
NC score	0.075461 (rank : 567)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	613	Target Neighborhood Hits	379	Shared Neighborhood Hits	134
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

FHL3_MOUSE
NC score	0.075378 (rank : 568)	θ value	0.00298849 (rank : 210)
Query Neighborhood Hits	613	Target Neighborhood Hits	424	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R059, Q9JLP5, Q9WUH3	Gene names	Fhl3
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

AD26A_MOUSE
NC score	0.075281 (rank : 569)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	613	Target Neighborhood Hits	165	Shared Neighborhood Hits	114
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

TR19L_MOUSE
NC score	0.075195 (rank : 570)	θ value	5.27518 (rank : 558)
Query Neighborhood Hits	613	Target Neighborhood Hits	85	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

SPR2F_HUMAN
NC score	0.075055 (rank : 571)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	613	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

ATS9_HUMAN
NC score	0.074826 (rank : 572)	θ value	0.000786445 (rank : 184)
Query Neighborhood Hits	613	Target Neighborhood Hits	219	Shared Neighborhood Hits	113
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

C1RB_MOUSE
NC score	0.074728 (rank : 573)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	613	Target Neighborhood Hits	380	Shared Neighborhood Hits	134
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

CO9_HUMAN
NC score	0.074370 (rank : 574)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	613	Target Neighborhood Hits	147	Shared Neighborhood Hits	71
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

TNR27_HUMAN
NC score	0.074237 (rank : 575)	θ value	3.0926 (rank : 515)
Query Neighborhood Hits	613	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

NRG2_MOUSE
NC score	0.074104 (rank : 576)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	613	Target Neighborhood Hits	392	Shared Neighborhood Hits	89
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

TNR18_HUMAN
NC score	0.073494 (rank : 577)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	613	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

EPHB4_HUMAN
NC score	0.073228 (rank : 578)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	613	Target Neighborhood Hits	1056	Shared Neighborhood Hits	158
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

APR3_HUMAN
NC score	0.072985 (rank : 579)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	613	Target Neighborhood Hits	50	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

FREM1_HUMAN
NC score	0.072850 (rank : 580)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	613	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

NRG4_MOUSE
NC score	0.072682 (rank : 581)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	613	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

SPON1_MOUSE
NC score	0.072532 (rank : 582)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	613	Target Neighborhood Hits	123	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

ZN330_HUMAN
NC score	0.072372 (rank : 583)	θ value	1.06291 (rank : 442)
Query Neighborhood Hits	613	Target Neighborhood Hits	83	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

ADA20_HUMAN
NC score	0.072076 (rank : 584)	θ value	0.21417 (rank : 334)
Query Neighborhood Hits	613	Target Neighborhood Hits	143	Shared Neighborhood Hits	92
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

CYR61_HUMAN
NC score	0.071205 (rank : 585)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	613	Target Neighborhood Hits	159	Shared Neighborhood Hits	84
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

BAI3_MOUSE
NC score	0.071002 (rank : 586)	θ value	0.813845 (rank : 415)
Query Neighborhood Hits	613	Target Neighborhood Hits	250	Shared Neighborhood Hits	73
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

SPR2B_MOUSE
NC score	0.070760 (rank : 587)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	613	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

KR132_HUMAN
NC score	0.070728 (rank : 588)	θ value	1.81305 (rank : 461)
Query Neighborhood Hits	613	Target Neighborhood Hits	69	Shared Neighborhood Hits	47
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

FREM1_MOUSE
NC score	0.070526 (rank : 589)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	613	Target Neighborhood Hits	163	Shared Neighborhood Hits	11
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

CYR61_MOUSE
NC score	0.070498 (rank : 590)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	613	Target Neighborhood Hits	156	Shared Neighborhood Hits	81
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

MBTP1_HUMAN
NC score	0.070379 (rank : 591)	θ value	0.813845 (rank : 422)
Query Neighborhood Hits	613	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

SPON1_HUMAN
NC score	0.069950 (rank : 592)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	613	Target Neighborhood Hits	117	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SRCH_HUMAN
NC score	0.069746 (rank : 593)	θ value	0.125558 (rank : 315)
Query Neighborhood Hits	613	Target Neighborhood Hits	225	Shared Neighborhood Hits	37
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

WISP2_HUMAN
NC score	0.069736 (rank : 594)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	613	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

C1R_HUMAN
NC score	0.069638 (rank : 595)	θ value	8.99809 (rank : 591)
Query Neighborhood Hits	613	Target Neighborhood Hits	364	Shared Neighborhood Hits	128
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

NOV_HUMAN
NC score	0.068594 (rank : 596)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	613	Target Neighborhood Hits	128	Shared Neighborhood Hits	69
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

BAI3_HUMAN
NC score	0.068171 (rank : 597)	θ value	0.62314 (rank : 400)
Query Neighborhood Hits	613	Target Neighborhood Hits	246	Shared Neighborhood Hits	70
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI2_MOUSE
NC score	0.067962 (rank : 598)	θ value	0.0148317 (rank : 242)
Query Neighborhood Hits	613	Target Neighborhood Hits	323	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

EREG_HUMAN
NC score	0.067547 (rank : 599)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	613	Target Neighborhood Hits	73	Shared Neighborhood Hits	47
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

BAI2_HUMAN
NC score	0.067508 (rank : 600)	θ value	0.0148317 (rank : 241)
Query Neighborhood Hits	613	Target Neighborhood Hits	332	Shared Neighborhood Hits	62
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

MLL3_MOUSE
NC score	0.067192 (rank : 601)	θ value	0.00665767 (rank : 225)
Query Neighborhood Hits	613	Target Neighborhood Hits	1399	Shared Neighborhood Hits	111
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ATS17_HUMAN
NC score	0.067166 (rank : 602)	θ value	0.0431538 (rank : 279)
Query Neighborhood Hits	613	Target Neighborhood Hits	194	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

WISP2_MOUSE
NC score	0.066914 (rank : 603)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	613	Target Neighborhood Hits	129	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

KR134_HUMAN
NC score	0.066778 (rank : 604)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	613	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

FINC_MOUSE
NC score	0.066666 (rank : 605)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	613	Target Neighborhood Hits	309	Shared Neighborhood Hits	66
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

SPR2I_MOUSE
NC score	0.066661 (rank : 606)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	613	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

SHBG_HUMAN
NC score	0.066623 (rank : 607)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	613	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SPR2E_MOUSE
NC score	0.066572 (rank : 608)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	613	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

EPHB6_HUMAN
NC score	0.066072 (rank : 609)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	613	Target Neighborhood Hits	912	Shared Neighborhood Hits	105
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

MBTP1_MOUSE
NC score	0.065682 (rank : 610)	θ value	0.813845 (rank : 423)
Query Neighborhood Hits	613	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTZ2, Q6PG67	Gene names	Mbtps1, S1p, Ski1
Domain Architecture
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin isozyme 1) (SKI-1) (Sterol-regulated luminal protease).

DKK3_MOUSE
NC score	0.065390 (rank : 611)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	613	Target Neighborhood Hits	83	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

MFGM_HUMAN
NC score	0.065044 (rank : 612)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	613	Target Neighborhood Hits	150	Shared Neighborhood Hits	82
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

TR19L_HUMAN
NC score	0.065036 (rank : 613)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	613	Target Neighborhood Hits	99	Shared Neighborhood Hits	56
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

CTGF_HUMAN
NC score	0.064878 (rank : 614)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	613	Target Neighborhood Hits	128	Shared Neighborhood Hits	68
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

MASP2_HUMAN
NC score	0.064742 (rank : 615)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	613	Target Neighborhood Hits	364	Shared Neighborhood Hits	122
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
NC score	0.064718 (rank : 616)	θ value	0.813845 (rank : 421)
Query Neighborhood Hits	613	Target Neighborhood Hits	382	Shared Neighborhood Hits	128
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

PGH2_MOUSE
NC score	0.064515 (rank : 617)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	613	Target Neighborhood Hits	113	Shared Neighborhood Hits	67
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

BAI1_HUMAN
NC score	0.064172 (rank : 618)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	613	Target Neighborhood Hits	375	Shared Neighborhood Hits	69
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

KR133_HUMAN
NC score	0.063912 (rank : 619)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	613	Target Neighborhood Hits	66	Shared Neighborhood Hits	48
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

EPHA1_HUMAN
NC score	0.063782 (rank : 620)	θ value	0.0961366 (rank : 303)
Query Neighborhood Hits	613	Target Neighborhood Hits	997	Shared Neighborhood Hits	121
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA2_MOUSE
NC score	0.063569 (rank : 621)	θ value	0.279714 (rank : 349)
Query Neighborhood Hits	613	Target Neighborhood Hits	1020	Shared Neighborhood Hits	121
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

ATS20_MOUSE
NC score	0.063491 (rank : 622)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	613	Target Neighborhood Hits	225	Shared Neighborhood Hits	107
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

FHL3_HUMAN
NC score	0.062795 (rank : 623)	θ value	0.0736092 (rank : 298)
Query Neighborhood Hits	613	Target Neighborhood Hits	354	Shared Neighborhood Hits	77
SwissProt Accessions	Q13643	Gene names	FHL3, SLIM2
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

FINC_HUMAN
NC score	0.062775 (rank : 624)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	613	Target Neighborhood Hits	302	Shared Neighborhood Hits	61
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

ZN330_MOUSE
NC score	0.062613 (rank : 625)	θ value	0.62314 (rank : 411)
Query Neighborhood Hits	613	Target Neighborhood Hits	86	Shared Neighborhood Hits	35
SwissProt Accessions	Q922H9, Q8C389, Q8K2M4	Gene names	Znf330, Noa36, Zfp330
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

EPHAA_HUMAN
NC score	0.062584 (rank : 626)	θ value	0.813845 (rank : 419)
Query Neighborhood Hits	613	Target Neighborhood Hits	960	Shared Neighborhood Hits	87
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHA7_HUMAN
NC score	0.062567 (rank : 627)	θ value	4.03905 (rank : 525)
Query Neighborhood Hits	613	Target Neighborhood Hits	1053	Shared Neighborhood Hits	137
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

ATS20_HUMAN
NC score	0.062065 (rank : 628)	θ value	2.36792 (rank : 477)
Query Neighborhood Hits	613	Target Neighborhood Hits	192	Shared Neighborhood Hits	89
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

EPHB4_MOUSE
NC score	0.062032 (rank : 629)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	613	Target Neighborhood Hits	1013	Shared Neighborhood Hits	123
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

SHBG_MOUSE
NC score	0.061866 (rank : 630)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	613	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

CTGF_MOUSE
NC score	0.061774 (rank : 631)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	613	Target Neighborhood Hits	124	Shared Neighborhood Hits	65
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

NRG2_HUMAN
NC score	0.061588 (rank : 632)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	613	Target Neighborhood Hits	419	Shared Neighborhood Hits	75
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

EPHB6_MOUSE
NC score	0.061557 (rank : 633)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	613	Target Neighborhood Hits	906	Shared Neighborhood Hits	88
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPHA1_MOUSE
NC score	0.061529 (rank : 634)	θ value	0.813845 (rank : 418)
Query Neighborhood Hits	613	Target Neighborhood Hits	958	Shared Neighborhood Hits	109
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

MASP1_HUMAN
NC score	0.060483 (rank : 635)	θ value	4.03905 (rank : 528)
Query Neighborhood Hits	613	Target Neighborhood Hits	369	Shared Neighborhood Hits	121
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

PGH2_HUMAN
NC score	0.060421 (rank : 636)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	613	Target Neighborhood Hits	103	Shared Neighborhood Hits	59
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

DKK3_HUMAN
NC score	0.060355 (rank : 637)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	613	Target Neighborhood Hits	74	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

FHL5_HUMAN
NC score	0.060278 (rank : 638)	θ value	0.0431538 (rank : 281)
Query Neighborhood Hits	613	Target Neighborhood Hits	523	Shared Neighborhood Hits	96
SwissProt Accessions	Q5TD97, Q5TD98, Q8WW21, Q9NQU2	Gene names	FHL5, ACT
Domain Architecture	No domain graphic available
Description	Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP- responsive element modulator in testis) (Activator of CREM in testis).

FHL2_MOUSE
NC score	0.060231 (rank : 639)	θ value	0.0563607 (rank : 289)
Query Neighborhood Hits	613	Target Neighborhood Hits	539	Shared Neighborhood Hits	111
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

BAI1_MOUSE
NC score	0.060086 (rank : 640)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	613	Target Neighborhood Hits	340	Shared Neighborhood Hits	63
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

IDD_HUMAN
NC score	0.060047 (rank : 641)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	613	Target Neighborhood Hits	127	Shared Neighborhood Hits	45
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

ODFP_MOUSE
NC score	0.060012 (rank : 642)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	613	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

MASP1_MOUSE
NC score	0.059573 (rank : 643)	θ value	0.813845 (rank : 420)
Query Neighborhood Hits	613	Target Neighborhood Hits	364	Shared Neighborhood Hits	121
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MLL3_HUMAN
NC score	0.059253 (rank : 644)	θ value	0.00175202 (rank : 203)
Query Neighborhood Hits	613	Target Neighborhood Hits	1644	Shared Neighborhood Hits	115
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CS1A_MOUSE
NC score	0.059225 (rank : 645)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	613	Target Neighborhood Hits	360	Shared Neighborhood Hits	121
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

TR13B_HUMAN
NC score	0.059181 (rank : 646)	θ value	0.163984 (rank : 331)
Query Neighborhood Hits	613	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	O14836, Q7Z6F5	Gene names	TNFRSF13B, TACI
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor) (CD267 antigen).

TMPS6_HUMAN
NC score	0.058896 (rank : 647)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	613	Target Neighborhood Hits	338	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

FHL2_HUMAN
NC score	0.058835 (rank : 648)	θ value	0.00390308 (rank : 216)
Query Neighborhood Hits	613	Target Neighborhood Hits	533	Shared Neighborhood Hits	103
SwissProt Accessions	Q14192, Q13229, Q13644, Q9P294	Gene names	FHL2, DRAL, SLIM3
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3) (LIM-domain protein DRAL).

CS1B_MOUSE
NC score	0.058781 (rank : 649)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	613	Target Neighborhood Hits	361	Shared Neighborhood Hits	120
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

TR13B_MOUSE
NC score	0.058738 (rank : 650)	θ value	1.38821 (rank : 457)
Query Neighborhood Hits	613	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ET35, Q9DBZ3	Gene names	Tnfrsf13b, Taci
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor).

EPHA2_HUMAN
NC score	0.058646 (rank : 651)	θ value	0.125558 (rank : 307)
Query Neighborhood Hits	613	Target Neighborhood Hits	1021	Shared Neighborhood Hits	100
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

MFRP_HUMAN
NC score	0.058351 (rank : 652)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	613	Target Neighborhood Hits	165	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

LCE3C_HUMAN
NC score	0.058046 (rank : 653)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	613	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

CSMD1_MOUSE
NC score	0.058028 (rank : 654)	θ value	0.279714 (rank : 347)
Query Neighborhood Hits	613	Target Neighborhood Hits	193	Shared Neighborhood Hits	68
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

FHL5_MOUSE
NC score	0.057566 (rank : 655)	θ value	0.0563607 (rank : 290)
Query Neighborhood Hits	613	Target Neighborhood Hits	463	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WTX7	Gene names	Fhl5, Act
Domain Architecture	No domain graphic available
Description	Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP- responsive element modulator in testis) (Activator of CREM in testis).

TRI42_MOUSE
NC score	0.057217 (rank : 656)	θ value	0.813845 (rank : 426)
Query Neighborhood Hits	613	Target Neighborhood Hits	316	Shared Neighborhood Hits	82
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

COCA1_MOUSE
NC score	0.056743 (rank : 657)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	613	Target Neighborhood Hits	467	Shared Neighborhood Hits	41
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

C1S_HUMAN
NC score	0.056739 (rank : 658)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	613	Target Neighborhood Hits	359	Shared Neighborhood Hits	123
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

NSD1_MOUSE
NC score	0.056552 (rank : 659)	θ value	7.1131e-05 (rank : 148)
Query Neighborhood Hits	613	Target Neighborhood Hits	472	Shared Neighborhood Hits	33
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PGH1_MOUSE
NC score	0.056288 (rank : 660)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	613	Target Neighborhood Hits	100	Shared Neighborhood Hits	56
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

KRA63_HUMAN
NC score	0.056232 (rank : 661)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	613	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q3LI67	Gene names	KRTAP6-3, KAP6.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 6-3.

COKA1_HUMAN
NC score	0.055882 (rank : 662)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	613	Target Neighborhood Hits	403	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

IDD_MOUSE
NC score	0.055516 (rank : 663)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	613	Target Neighborhood Hits	151	Shared Neighborhood Hits	45
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

EPHB2_MOUSE
NC score	0.055434 (rank : 664)	θ value	0.00509761 (rank : 220)
Query Neighborhood Hits	613	Target Neighborhood Hits	982	Shared Neighborhood Hits	89
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB2_HUMAN
NC score	0.055429 (rank : 665)	θ value	0.00509761 (rank : 219)
Query Neighborhood Hits	613	Target Neighborhood Hits	983	Shared Neighborhood Hits	89
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHA3_MOUSE
NC score	0.055410 (rank : 666)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	613	Target Neighborhood Hits	1009	Shared Neighborhood Hits	97
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHA7_MOUSE
NC score	0.055392 (rank : 667)	θ value	5.27518 (rank : 549)
Query Neighborhood Hits	613	Target Neighborhood Hits	1025	Shared Neighborhood Hits	113
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

COCA1_HUMAN
NC score	0.055220 (rank : 668)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	613	Target Neighborhood Hits	458	Shared Neighborhood Hits	42
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

EPHA3_HUMAN
NC score	0.055159 (rank : 669)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	613	Target Neighborhood Hits	1005	Shared Neighborhood Hits	97
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHA6_HUMAN
NC score	0.054898 (rank : 670)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	613	Target Neighborhood Hits	959	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

THYG_HUMAN
NC score	0.054885 (rank : 671)	θ value	0.279714 (rank : 360)
Query Neighborhood Hits	613	Target Neighborhood Hits	154	Shared Neighborhood Hits	70
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

SPR2E_HUMAN
NC score	0.054695 (rank : 672)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	613	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

CSMD1_HUMAN
NC score	0.054265 (rank : 673)	θ value	0.163984 (rank : 321)
Query Neighborhood Hits	613	Target Neighborhood Hits	176	Shared Neighborhood Hits	57
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

ATS16_MOUSE
NC score	0.054069 (rank : 674)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	613	Target Neighborhood Hits	179	Shared Neighborhood Hits	82
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_HUMAN
NC score	0.053931 (rank : 675)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	613	Target Neighborhood Hits	208	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

TMPS6_MOUSE
NC score	0.053908 (rank : 676)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	613	Target Neighborhood Hits	341	Shared Neighborhood Hits	115
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

NOV_MOUSE
NC score	0.053847 (rank : 677)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	613	Target Neighborhood Hits	130	Shared Neighborhood Hits	66
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

EPHB1_HUMAN
NC score	0.053587 (rank : 678)	θ value	1.06291 (rank : 434)
Query Neighborhood Hits	613	Target Neighborhood Hits	988	Shared Neighborhood Hits	100
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

WFDC2_HUMAN
NC score	0.053344 (rank : 679)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	613	Target Neighborhood Hits	73	Shared Neighborhood Hits	47
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

EPHB3_HUMAN
NC score	0.053275 (rank : 680)	θ value	0.62314 (rank : 401)
Query Neighborhood Hits	613	Target Neighborhood Hits	996	Shared Neighborhood Hits	83
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

EPHA6_MOUSE
NC score	0.052918 (rank : 681)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	613	Target Neighborhood Hits	946	Shared Neighborhood Hits	78
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

ATS19_MOUSE
NC score	0.052855 (rank : 682)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	613	Target Neighborhood Hits	188	Shared Neighborhood Hits	61
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

FHL1_MOUSE
NC score	0.052834 (rank : 683)	θ value	0.0736092 (rank : 297)
Query Neighborhood Hits	613	Target Neighborhood Hits	462	Shared Neighborhood Hits	84
SwissProt Accessions	P97447, O55181, Q8K318	Gene names	Fhl1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM) (KyoT) (RBP-associated molecule 14-1) (RAM14-1).

EDAR_HUMAN
NC score	0.052483 (rank : 684)	θ value	4.03905 (rank : 522)
Query Neighborhood Hits	613	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

FHL1_HUMAN
NC score	0.051497 (rank : 685)	θ value	0.0252991 (rank : 264)
Query Neighborhood Hits	613	Target Neighborhood Hits	436	Shared Neighborhood Hits	76
SwissProt Accessions	Q13642, O95212, Q13230, Q13645, Q5M7Y6, Q9NZ40, Q9UKZ8, Q9Y630	Gene names	FHL1, SLIM1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM).

SPR2F_MOUSE
NC score	0.051371 (rank : 686)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	613	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

EPHB3_MOUSE
NC score	0.051230 (rank : 687)	θ value	0.365318 (rank : 367)
Query Neighborhood Hits	613	Target Neighborhood Hits	996	Shared Neighborhood Hits	79
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

ATS12_MOUSE
NC score	0.051023 (rank : 688)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	613	Target Neighborhood Hits	220	Shared Neighborhood Hits	86
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATL3_HUMAN
NC score	0.050989 (rank : 689)	θ value	4.03905 (rank : 520)
Query Neighborhood Hits	613	Target Neighborhood Hits	414	Shared Neighborhood Hits	64
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

EPHA4_MOUSE
NC score	0.050901 (rank : 690)	θ value	8.99809 (rank : 595)
Query Neighborhood Hits	613	Target Neighborhood Hits	982	Shared Neighborhood Hits	83
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA5_HUMAN
NC score	0.050694 (rank : 691)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	613	Target Neighborhood Hits	1009	Shared Neighborhood Hits	75
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

WISP1_MOUSE
NC score	0.050588 (rank : 692)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	613	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

NSD1_HUMAN
NC score	0.050472 (rank : 693)	θ value	0.00228821 (rank : 207)
Query Neighborhood Hits	613	Target Neighborhood Hits	427	Shared Neighborhood Hits	28
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

ATS7_HUMAN
NC score	0.050423 (rank : 694)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	613	Target Neighborhood Hits	169	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

THYG_MOUSE
NC score	0.050252 (rank : 695)	θ value	3.0926 (rank : 513)
Query Neighborhood Hits	613	Target Neighborhood Hits	161	Shared Neighborhood Hits	77
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

SPIT1_HUMAN
NC score	0.050087 (rank : 696)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	613	Target Neighborhood Hits	100	Shared Neighborhood Hits	42
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

ATS3_HUMAN
NC score	0.050034 (rank : 697)	θ value	0.62314 (rank : 399)
Query Neighborhood Hits	613	Target Neighborhood Hits	179	Shared Neighborhood Hits	69
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS12_HUMAN
NC score	0.049740 (rank : 698)	θ value	1.06291 (rank : 431)
Query Neighborhood Hits	613	Target Neighborhood Hits	251	Shared Neighborhood Hits	79
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS14_HUMAN
NC score	0.049325 (rank : 699)	θ value	0.21417 (rank : 335)
Query Neighborhood Hits	613	Target Neighborhood Hits	382	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

PCSK9_HUMAN
NC score	0.048122 (rank : 700)	θ value	4.03905 (rank : 529)
Query Neighborhood Hits	613	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NBP7, Q5PSM5	Gene names	PCSK9, NARC1
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 9 precursor (EC 3.4.21.-) (Proprotein convertase PC9) (Subtilisin/kexin-like protease PC9) (Neural apoptosis-regulated convertase 1) (NARC-1).

TRI42_HUMAN
NC score	0.047665 (rank : 701)	θ value	0.21417 (rank : 341)
Query Neighborhood Hits	613	Target Neighborhood Hits	283	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

MLL2_HUMAN
NC score	0.046463 (rank : 702)	θ value	0.279714 (rank : 354)
Query Neighborhood Hits	613	Target Neighborhood Hits	1788	Shared Neighborhood Hits	91
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

GP179_HUMAN
NC score	0.045310 (rank : 703)	θ value	0.62314 (rank : 402)
Query Neighborhood Hits	613	Target Neighborhood Hits	372	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

CSMD2_HUMAN
NC score	0.044657 (rank : 704)	θ value	6.88961 (rank : 569)
Query Neighborhood Hits	613	Target Neighborhood Hits	188	Shared Neighborhood Hits	56
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

SEM5B_MOUSE
NC score	0.044541 (rank : 705)	θ value	8.99809 (rank : 603)
Query Neighborhood Hits	613	Target Neighborhood Hits	190	Shared Neighborhood Hits	67
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

ATS2_HUMAN
NC score	0.044415 (rank : 706)	θ value	8.99809 (rank : 590)
Query Neighborhood Hits	613	Target Neighborhood Hits	179	Shared Neighborhood Hits	65
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

FA76B_MOUSE
NC score	0.043552 (rank : 707)	θ value	0.0252991 (rank : 263)
Query Neighborhood Hits	613	Target Neighborhood Hits	181	Shared Neighborhood Hits	16
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

SEM5B_HUMAN
NC score	0.042744 (rank : 708)	θ value	0.813845 (rank : 424)
Query Neighborhood Hits	613	Target Neighborhood Hits	178	Shared Neighborhood Hits	60
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

CILP1_HUMAN
NC score	0.041989 (rank : 709)	θ value	8.99809 (rank : 592)
Query Neighborhood Hits	613	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

ATS5_HUMAN
NC score	0.041888 (rank : 710)	θ value	4.03905 (rank : 521)
Query Neighborhood Hits	613	Target Neighborhood Hits	141	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

SEM5A_HUMAN
NC score	0.041350 (rank : 711)	θ value	4.03905 (rank : 530)
Query Neighborhood Hits	613	Target Neighborhood Hits	177	Shared Neighborhood Hits	60
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

TMPS7_MOUSE
NC score	0.041276 (rank : 712)	θ value	1.06291 (rank : 439)
Query Neighborhood Hits	613	Target Neighborhood Hits	275	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

CNBP_HUMAN
NC score	0.040706 (rank : 713)	θ value	1.06291 (rank : 433)
Query Neighborhood Hits	613	Target Neighborhood Hits	196	Shared Neighborhood Hits	46
SwissProt Accessions	P62633, P20694, Q5QJR0, Q6PJI7, Q96NV3	Gene names	CNBP, ZNF9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

KRA33_HUMAN
NC score	0.040412 (rank : 714)	θ value	6.88961 (rank : 576)
Query Neighborhood Hits	613	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYR6, Q52LP0	Gene names	KRTAP3-3, KAP3.3, KRTAP3.3
Domain Architecture
Description	Keratin-associated protein 3-3 (Keratin-associated protein 3.3) (High sulfur keratin-associated protein 3.3).

TMPS7_HUMAN
NC score	0.039823 (rank : 715)	θ value	1.06291 (rank : 438)
Query Neighborhood Hits	613	Target Neighborhood Hits	275	Shared Neighborhood Hits	65
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

FAM5B_MOUSE
NC score	0.038366 (rank : 716)	θ value	5.27518 (rank : 552)
Query Neighborhood Hits	613	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

PHF7_HUMAN
NC score	0.036619 (rank : 717)	θ value	3.0926 (rank : 506)
Query Neighborhood Hits	613	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

ZCHC4_HUMAN
NC score	0.034140 (rank : 718)	θ value	0.813845 (rank : 427)
Query Neighborhood Hits	613	Target Neighborhood Hits	76	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H5U6, Q5IW78, Q96AN7	Gene names	ZCCHC4
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 4.

TYRP1_HUMAN
NC score	0.033845 (rank : 719)	θ value	1.81305 (rank : 469)
Query Neighborhood Hits	613	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P17643, P78468, P78469, Q13721, Q15679	Gene names	TYRP1, CAS2, TYRP, TYRRP
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75).

EZH1_MOUSE
NC score	0.032967 (rank : 720)	θ value	8.99809 (rank : 596)
Query Neighborhood Hits	613	Target Neighborhood Hits	126	Shared Neighborhood Hits	48
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

WFDC8_HUMAN
NC score	0.032372 (rank : 721)	θ value	2.36792 (rank : 489)
Query Neighborhood Hits	613	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

TNR17_MOUSE
NC score	0.031027 (rank : 722)	θ value	0.365318 (rank : 374)
Query Neighborhood Hits	613	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	O88472	Gene names	Tnfrsf17, Bcm, Bcma
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein).

C4BP_HUMAN
NC score	0.030604 (rank : 723)	θ value	0.813845 (rank : 416)
Query Neighborhood Hits	613	Target Neighborhood Hits	92	Shared Neighborhood Hits	27
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

MYCB2_HUMAN
NC score	0.029961 (rank : 724)	θ value	0.279714 (rank : 358)
Query Neighborhood Hits	613	Target Neighborhood Hits	390	Shared Neighborhood Hits	32
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

FBX5_HUMAN
NC score	0.029883 (rank : 725)	θ value	0.125558 (rank : 309)
Query Neighborhood Hits	613	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKT4, Q8WV29, Q9UGC8	Gene names	FBXO5, EMI1, FBX5
Domain Architecture	No domain graphic available
Description	F-box only protein 5 (Early mitotic inhibitor 1).

CNBP_MOUSE
NC score	0.029879 (rank : 726)	θ value	6.88961 (rank : 568)
Query Neighborhood Hits	613	Target Neighborhood Hits	215	Shared Neighborhood Hits	42
SwissProt Accessions	P53996, Q80Y06, Q8BP23	Gene names	Cnbp, Cnbp1, Znf9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

MYST4_MOUSE
NC score	0.029194 (rank : 727)	θ value	0.125558 (rank : 314)
Query Neighborhood Hits	613	Target Neighborhood Hits	416	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PINC_HUMAN
NC score	0.028098 (rank : 728)	θ value	5.27518 (rank : 557)
Query Neighborhood Hits	613	Target Neighborhood Hits	231	Shared Neighborhood Hits	29
SwissProt Accessions	P48059, Q53TE0, Q9BS44	Gene names	LIMS1
Domain Architecture
Description	Protein PINCH (Particularly interesting new Cys-His protein) (LIM and senescent cell antigen-like domains 1) (NY-REN-48 antigen).

ENTK_MOUSE
NC score	0.028003 (rank : 729)	θ value	4.03905 (rank : 524)
Query Neighborhood Hits	613	Target Neighborhood Hits	338	Shared Neighborhood Hits	57
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ZN224_HUMAN
NC score	0.026723 (rank : 730)	θ value	0.0193708 (rank : 258)
Query Neighborhood Hits	613	Target Neighborhood Hits	808	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NZL3, Q86V10, Q8IZC8, Q9UID9, Q9Y2P6	Gene names	ZNF224, BMZF2, ZNF255
Domain Architecture
Description	Zinc finger protein 224 (Zinc finger protein 255) (Bone marrow zinc finger 2) (BMZF-2).

ZN441_HUMAN
NC score	0.026605 (rank : 731)	θ value	0.00020696 (rank : 163)
Query Neighborhood Hits	613	Target Neighborhood Hits	754	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N8Z8	Gene names	ZNF441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 441.

MYST4_HUMAN
NC score	0.026529 (rank : 732)	θ value	0.125558 (rank : 313)
Query Neighborhood Hits	613	Target Neighborhood Hits	671	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

TRAF2_HUMAN
NC score	0.025777 (rank : 733)	θ value	0.125558 (rank : 318)
Query Neighborhood Hits	613	Target Neighborhood Hits	402	Shared Neighborhood Hits	48
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

ZN611_HUMAN
NC score	0.025450 (rank : 734)	θ value	0.000270298 (rank : 170)
Query Neighborhood Hits	613	Target Neighborhood Hits	769	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N823, Q69YG9	Gene names	ZNF611
Domain Architecture	No domain graphic available
Description	Zinc finger protein 611.

ZNF77_HUMAN
NC score	0.025448 (rank : 735)	θ value	0.00509761 (rank : 223)
Query Neighborhood Hits	613	Target Neighborhood Hits	759	Shared Neighborhood Hits	84
SwissProt Accessions	Q15935, Q86XJ3, Q9NPP0	Gene names	ZNF77
Domain Architecture	No domain graphic available
Description	Zinc finger protein 77 (ZNFpT1).

ZNF44_HUMAN
NC score	0.025293 (rank : 736)	θ value	0.0193708 (rank : 260)
Query Neighborhood Hits	613	Target Neighborhood Hits	757	Shared Neighborhood Hits	83
SwissProt Accessions	P15621, P17018, Q9ULZ7	Gene names	ZNF44, KOX7
Domain Architecture
Description	Zinc finger protein 44 (Zinc finger protein KOX7) (Gonadotropin- inducible transcription repressor 2) (GIOT-2).

CFAH_HUMAN
NC score	0.025125 (rank : 737)	θ value	5.27518 (rank : 544)
Query Neighborhood Hits	613	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

ZN709_HUMAN
NC score	0.024633 (rank : 738)	θ value	0.00390308 (rank : 218)
Query Neighborhood Hits	613	Target Neighborhood Hits	746	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N972	Gene names	ZNF709
Domain Architecture	No domain graphic available
Description	Zinc finger protein 709.

MYCB2_MOUSE
NC score	0.024623 (rank : 739)	θ value	8.99809 (rank : 602)
Query Neighborhood Hits	613	Target Neighborhood Hits	307	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

ZN189_HUMAN
NC score	0.024591 (rank : 740)	θ value	0.365318 (rank : 378)
Query Neighborhood Hits	613	Target Neighborhood Hits	754	Shared Neighborhood Hits	79
SwissProt Accessions	O75820, O75802, Q5T7D9, Q9UBL4, Q9UPE9, Q9UPF0, Q9UPF1	Gene names	ZNF189
Domain Architecture
Description	Zinc finger protein 189.

ZN227_HUMAN
NC score	0.024466 (rank : 741)	θ value	0.813845 (rank : 428)
Query Neighborhood Hits	613	Target Neighborhood Hits	781	Shared Neighborhood Hits	89
SwissProt Accessions	Q86WZ6	Gene names	ZNF227
Domain Architecture	No domain graphic available
Description	Zinc finger protein 227.

ZFP28_MOUSE
NC score	0.024336 (rank : 742)	θ value	0.21417 (rank : 342)
Query Neighborhood Hits	613	Target Neighborhood Hits	782	Shared Neighborhood Hits	83
SwissProt Accessions	P10078, Q61776, Q8BT11, Q8C836	Gene names	Zfp28, Mkr5, Zfp-28
Domain Architecture
Description	Zinc finger protein 28 (Zfp-28) (Protein mKR5).

MDFI_HUMAN
NC score	0.024226 (rank : 743)	θ value	3.0926 (rank : 505)
Query Neighborhood Hits	613	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	Q99750	Gene names	MDFI
Domain Architecture	No domain graphic available
Description	MyoD family inhibitor (Myogenic repressor I-mf).

AIRE_MOUSE
NC score	0.024195 (rank : 744)	θ value	2.36792 (rank : 475)
Query Neighborhood Hits	613	Target Neighborhood Hits	196	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

MYST3_MOUSE
NC score	0.024122 (rank : 745)	θ value	0.365318 (rank : 372)
Query Neighborhood Hits	613	Target Neighborhood Hits	688	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

FAM5C_MOUSE
NC score	0.023897 (rank : 746)	θ value	1.38821 (rank : 451)
Query Neighborhood Hits	613	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q499E0, Q8K0R9	Gene names	Fam5c
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor.

ZN334_HUMAN
NC score	0.023869 (rank : 747)	θ value	0.0193708 (rank : 259)
Query Neighborhood Hits	613	Target Neighborhood Hits	778	Shared Neighborhood Hits	84
SwissProt Accessions	Q9HCZ1, Q5T6U2, Q9NVW4	Gene names	ZNF334
Domain Architecture
Description	Zinc finger protein 334.

FAM5C_HUMAN
NC score	0.023858 (rank : 748)	θ value	1.38821 (rank : 450)
Query Neighborhood Hits	613	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q76B58, O95726	Gene names	FAM5C, DBCCR1L, DBCCR1L1
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor (DBCCR1-like protein 1).

ZN613_HUMAN
NC score	0.023755 (rank : 749)	θ value	0.00298849 (rank : 215)
Query Neighborhood Hits	613	Target Neighborhood Hits	746	Shared Neighborhood Hits	80
SwissProt Accessions	Q6PF04, Q96SS9	Gene names	ZNF613
Domain Architecture	No domain graphic available
Description	Zinc finger protein 613.

TTY6_HUMAN
NC score	0.023550 (rank : 750)	θ value	3.0926 (rank : 516)
Query Neighborhood Hits	613	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXH5	Gene names	TTTY6, TTY6
Domain Architecture	No domain graphic available
Description	Transcript Y 6 protein.

ZN678_HUMAN
NC score	0.023447 (rank : 751)	θ value	0.47712 (rank : 397)
Query Neighborhood Hits	613	Target Neighborhood Hits	761	Shared Neighborhood Hits	87
SwissProt Accessions	Q5SXM1, Q8IVQ9	Gene names	ZNF678
Domain Architecture	No domain graphic available
Description	Zinc finger protein 678.

ZN600_HUMAN
NC score	0.023433 (rank : 752)	θ value	0.0330416 (rank : 277)
Query Neighborhood Hits	613	Target Neighborhood Hits	774	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZNG1, Q6MZR0	Gene names	ZNF600
Domain Architecture	No domain graphic available
Description	Zinc finger protein 600.

ZN615_HUMAN
NC score	0.023375 (rank : 753)	θ value	8.99809 (rank : 611)
Query Neighborhood Hits	613	Target Neighborhood Hits	775	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N8J6	Gene names	ZNF615
Domain Architecture	No domain graphic available
Description	Zinc finger protein 615.

ZNF28_HUMAN
NC score	0.023357 (rank : 754)	θ value	0.00509761 (rank : 222)
Query Neighborhood Hits	613	Target Neighborhood Hits	760	Shared Neighborhood Hits	81
SwissProt Accessions	P17035, Q5HYM9, Q6ZML9, Q6ZN56	Gene names	ZNF28, KOX24
Domain Architecture	No domain graphic available
Description	Zinc finger protein 28 (Zinc finger protein KOX24).

ZN286_HUMAN
NC score	0.023016 (rank : 755)	θ value	0.00035302 (rank : 177)
Query Neighborhood Hits	613	Target Neighborhood Hits	775	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HBT8, Q96JF3	Gene names	ZNF286, KIAA1874
Domain Architecture
Description	Zinc finger protein 286.

ZN564_HUMAN
NC score	0.022999 (rank : 756)	θ value	6.88961 (rank : 587)
Query Neighborhood Hits	613	Target Neighborhood Hits	746	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TBZ8	Gene names	ZNF564
Domain Architecture	No domain graphic available
Description	Zinc finger protein 564.

ZN208_HUMAN
NC score	0.022990 (rank : 757)	θ value	4.03905 (rank : 537)
Query Neighborhood Hits	613	Target Neighborhood Hits	771	Shared Neighborhood Hits	88
SwissProt Accessions	O43345	Gene names	ZNF208, ZNF91L
Domain Architecture
Description	Zinc finger protein 208.

ZN418_HUMAN
NC score	0.022887 (rank : 758)	θ value	1.81305 (rank : 472)
Query Neighborhood Hits	613	Target Neighborhood Hits	776	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TF45, Q670L5, Q96N18	Gene names	ZNF418, KIAA1956
Domain Architecture
Description	Zinc finger protein 418.

ZN283_HUMAN
NC score	0.022854 (rank : 759)	θ value	0.47712 (rank : 395)
Query Neighborhood Hits	613	Target Neighborhood Hits	760	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N7M2	Gene names	ZNF283
Domain Architecture	No domain graphic available
Description	Zinc finger protein 283.

ZN595_HUMAN
NC score	0.022684 (rank : 760)	θ value	6.88961 (rank : 588)
Query Neighborhood Hits	613	Target Neighborhood Hits	798	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IYB9	Gene names	ZNF595
Domain Architecture	No domain graphic available
Description	Zinc finger protein 595.

AIRE_HUMAN
NC score	0.022446 (rank : 761)	θ value	5.27518 (rank : 542)
Query Neighborhood Hits	613	Target Neighborhood Hits	144	Shared Neighborhood Hits	17
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

MYST3_HUMAN
NC score	0.022210 (rank : 762)	θ value	0.365318 (rank : 371)
Query Neighborhood Hits	613	Target Neighborhood Hits	772	Shared Neighborhood Hits	26
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

ZN429_HUMAN
NC score	0.022125 (rank : 763)	θ value	0.279714 (rank : 363)
Query Neighborhood Hits	613	Target Neighborhood Hits	766	Shared Neighborhood Hits	82
SwissProt Accessions	Q86V71	Gene names	ZNF429
Domain Architecture
Description	Zinc finger protein 429.

ZN439_HUMAN
NC score	0.022100 (rank : 764)	θ value	0.813845 (rank : 429)
Query Neighborhood Hits	613	Target Neighborhood Hits	763	Shared Neighborhood Hits	81
SwissProt Accessions	Q8NDP4, Q8IYZ7, Q96SU1	Gene names	ZNF439
Domain Architecture
Description	Zinc finger protein 439.

ZFP60_MOUSE
NC score	0.022035 (rank : 765)	θ value	1.06291 (rank : 441)
Query Neighborhood Hits	613	Target Neighborhood Hits	754	Shared Neighborhood Hits	79
SwissProt Accessions	P16374, Q61135	Gene names	Zfp60, Mfg3
Domain Architecture
Description	Zinc finger protein 60 (Zfp-60) (Zinc finger protein Mfg-3).

FHR4_HUMAN
NC score	0.022017 (rank : 766)	θ value	1.38821 (rank : 452)
Query Neighborhood Hits	613	Target Neighborhood Hits	75	Shared Neighborhood Hits	25
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

ZN682_HUMAN
NC score	0.021983 (rank : 767)	θ value	0.365318 (rank : 379)
Query Neighborhood Hits	613	Target Neighborhood Hits	779	Shared Neighborhood Hits	81
SwissProt Accessions	O95780, Q96JV9	Gene names	ZNF682
Domain Architecture	No domain graphic available
Description	Zinc finger protein 682.

TNR17_HUMAN
NC score	0.021935 (rank : 768)	θ value	4.03905 (rank : 533)
Query Neighborhood Hits	613	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q02223	Gene names	TNFRSF17, BCM, BCMA
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD269 antigen).

TCF17_HUMAN
NC score	0.021927 (rank : 769)	θ value	3.0926 (rank : 511)
Query Neighborhood Hits	613	Target Neighborhood Hits	797	Shared Neighborhood Hits	88
SwissProt Accessions	O60765, Q9UNJ8	Gene names	ZNF354A, EZNF, HKL1, TCF17
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF).

ZNF14_HUMAN
NC score	0.021923 (rank : 770)	θ value	1.81305 (rank : 474)
Query Neighborhood Hits	613	Target Neighborhood Hits	760	Shared Neighborhood Hits	78
SwissProt Accessions	P17017, Q9ULZ5	Gene names	ZNF14, GIOT4, KOX6
Domain Architecture
Description	Zinc finger protein 14 (Zinc finger protein KOX6) (Gonadotropin- inducible transcription repressor 4) (GIOT-4).

ZN319_HUMAN
NC score	0.021909 (rank : 771)	θ value	6.88961 (rank : 584)
Query Neighborhood Hits	613	Target Neighborhood Hits	772	Shared Neighborhood Hits	78
SwissProt Accessions	Q9P2F9	Gene names	ZNF319, KIAA1388
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

ZNF7_HUMAN
NC score	0.021893 (rank : 772)	θ value	0.21417 (rank : 344)
Query Neighborhood Hits	613	Target Neighborhood Hits	770	Shared Neighborhood Hits	86
SwissProt Accessions	P17097, P17015	Gene names	ZNF7, KOX4
Domain Architecture
Description	Zinc finger protein 7 (Zinc finger protein KOX4) (Zinc finger protein HF.16).

ZN670_HUMAN
NC score	0.021719 (rank : 773)	θ value	0.21417 (rank : 343)
Query Neighborhood Hits	613	Target Neighborhood Hits	736	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BS34	Gene names	ZNF670
Domain Architecture	No domain graphic available
Description	Zinc finger protein 670.

ZN432_HUMAN
NC score	0.021595 (rank : 774)	θ value	1.81305 (rank : 473)
Query Neighborhood Hits	613	Target Neighborhood Hits	764	Shared Neighborhood Hits	77
SwissProt Accessions	O94892	Gene names	ZNF432, KIAA0798
Domain Architecture
Description	Zinc finger protein 432.

ZN605_HUMAN
NC score	0.021520 (rank : 775)	θ value	1.06291 (rank : 443)
Query Neighborhood Hits	613	Target Neighborhood Hits	753	Shared Neighborhood Hits	77
SwissProt Accessions	Q86T29, Q86T91	Gene names	ZNF605
Domain Architecture	No domain graphic available
Description	Zinc finger protein 605.

ZN669_HUMAN
NC score	0.021444 (rank : 776)	θ value	0.62314 (rank : 412)
Query Neighborhood Hits	613	Target Neighborhood Hits	746	Shared Neighborhood Hits	77
SwissProt Accessions	Q96BR6, Q5VT39, Q9H9Q6	Gene names	ZNF669
Domain Architecture	No domain graphic available
Description	Zinc finger protein 669.

ZN563_HUMAN
NC score	0.021437 (rank : 777)	θ value	3.0926 (rank : 517)
Query Neighborhood Hits	613	Target Neighborhood Hits	754	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TA94, Q8NAT7	Gene names	ZNF563
Domain Architecture	No domain graphic available
Description	Zinc finger protein 563.

ZN383_HUMAN
NC score	0.021426 (rank : 778)	θ value	8.99809 (rank : 610)
Query Neighborhood Hits	613	Target Neighborhood Hits	758	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NA42, Q6X2C7	Gene names	ZNF383
Domain Architecture	No domain graphic available
Description	Zinc finger protein 383.

ZN337_HUMAN
NC score	0.021234 (rank : 779)	θ value	6.88961 (rank : 585)
Query Neighborhood Hits	613	Target Neighborhood Hits	781	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y3M9, Q9Y3Y5	Gene names	ZNF337
Domain Architecture
Description	Zinc finger protein 337.

ZN490_HUMAN
NC score	0.021226 (rank : 780)	θ value	2.36792 (rank : 495)
Query Neighborhood Hits	613	Target Neighborhood Hits	754	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ULM2	Gene names	ZNF490, KIAA1198
Domain Architecture
Description	Zinc finger protein 490.

ZN350_HUMAN
NC score	0.021214 (rank : 781)	θ value	0.0330416 (rank : 276)
Query Neighborhood Hits	613	Target Neighborhood Hits	738	Shared Neighborhood Hits	74
SwissProt Accessions	Q9GZX5, Q9HAQ4	Gene names	ZNF350, ZBRK1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 350 (Zinc-finger protein ZBRK1) (Zinc finger and BRCA1-interacting protein with a KRAB domain 1) (KRAB zinc finger protein ZFQR).

ZSCA2_HUMAN
NC score	0.021209 (rank : 782)	θ value	5.27518 (rank : 566)
Query Neighborhood Hits	613	Target Neighborhood Hits	803	Shared Neighborhood Hits	86
SwissProt Accessions	Q7Z7L9, Q6ZQY9, Q9NWU4	Gene names	ZSCAN2, ZFP29
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29 homolog) (Zfp-29).

ZN271_HUMAN
NC score	0.021110 (rank : 783)	θ value	8.99809 (rank : 608)
Query Neighborhood Hits	613	Target Neighborhood Hits	769	Shared Neighborhood Hits	80
SwissProt Accessions	Q14591, Q96T29, Q9BSX2, Q9UN33, Q9Y5B7	Gene names	ZNF271, ZNFEB
Domain Architecture	No domain graphic available
Description	Zinc finger protein 271 (Zinc finger protein HZF7) (Zinc finger protein ZNFphex133) (Epstein-Barr virus-induced zinc finger protein) (ZNF-EB) (CT-ZFP48) (Zinc finger protein dp) (ZNF-dp).

ZFP59_MOUSE
NC score	0.021087 (rank : 784)	θ value	4.03905 (rank : 536)
Query Neighborhood Hits	613	Target Neighborhood Hits	768	Shared Neighborhood Hits	79
SwissProt Accessions	P16373, Q61849	Gene names	Zfp59, Mfg2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 59 (Zfp-59) (Zinc finger protein Mfg-2).

PRDM1_MOUSE
NC score	0.021071 (rank : 785)	θ value	0.00665767 (rank : 227)
Query Neighborhood Hits	613	Target Neighborhood Hits	766	Shared Neighborhood Hits	67
SwissProt Accessions	Q60636	Gene names	Prdm1, Blimp1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1).

ZN101_HUMAN
NC score	0.021064 (rank : 786)	θ value	0.62314 (rank : 410)
Query Neighborhood Hits	613	Target Neighborhood Hits	731	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IZC7	Gene names	ZNF101
Domain Architecture	No domain graphic available
Description	Zinc finger protein 101 (Zinc finger protein HZF12).

ZN266_HUMAN
NC score	0.021062 (rank : 787)	θ value	8.99809 (rank : 607)
Query Neighborhood Hits	613	Target Neighborhood Hits	750	Shared Neighborhood Hits	77
SwissProt Accessions	Q14584, Q6IQ07, Q6U8A5, Q8IVG3, Q8WVX1, Q96SX9	Gene names	ZNF266, KIAA2007
Domain Architecture	No domain graphic available
Description	Zinc finger protein 266 (Zinc finger protein HZF1).

ZN211_HUMAN
NC score	0.020822 (rank : 788)	θ value	6.88961 (rank : 583)
Query Neighborhood Hits	613	Target Neighborhood Hits	733	Shared Neighborhood Hits	77
SwissProt Accessions	Q13398	Gene names	ZNF211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 211 (Zinc finger protein C2H2-25).

ZN620_HUMAN
NC score	0.020808 (rank : 789)	θ value	0.47712 (rank : 396)
Query Neighborhood Hits	613	Target Neighborhood Hits	744	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZNG0, Q8N223	Gene names	ZNF620
Domain Architecture	No domain graphic available
Description	Zinc finger protein 620.

ZN440_HUMAN
NC score	0.020725 (rank : 790)	θ value	2.36792 (rank : 494)
Query Neighborhood Hits	613	Target Neighborhood Hits	750	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IYI8, Q8N1R9	Gene names	ZNF440
Domain Architecture
Description	Zinc finger protein 440.

PRDM1_HUMAN
NC score	0.020705 (rank : 791)	θ value	0.0252991 (rank : 267)
Query Neighborhood Hits	613	Target Neighborhood Hits	734	Shared Neighborhood Hits	67
SwissProt Accessions	O75626	Gene names	PRDM1, BLIMP1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1) (Positive regulatory domain I-binding factor 1) (PRDI- binding factor 1) (PRDI-BF1).

ZN260_HUMAN
NC score	0.020662 (rank : 792)	θ value	2.36792 (rank : 492)
Query Neighborhood Hits	613	Target Neighborhood Hits	757	Shared Neighborhood Hits	78
SwissProt Accessions	Q3ZCT1	Gene names	ZNF260, ZFP260
Domain Architecture	No domain graphic available
Description	Zinc finger protein 260 (Zfp-260).

ZN195_HUMAN
NC score	0.020596 (rank : 793)	θ value	8.99809 (rank : 606)
Query Neighborhood Hits	613	Target Neighborhood Hits	760	Shared Neighborhood Hits	83
SwissProt Accessions	O14628	Gene names	ZNF195, ZNFP104
Domain Architecture
Description	Zinc finger protein 195.

TCF17_MOUSE
NC score	0.020574 (rank : 794)	θ value	4.03905 (rank : 532)
Query Neighborhood Hits	613	Target Neighborhood Hits	786	Shared Neighborhood Hits	77
SwissProt Accessions	Q61751	Gene names	Znf354a, Kid1, Tcf17, Zfp354a
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Renal transcription factor Kid-1) (Kidney, ischemia, and developmentally- regulated protein 1).

ZN154_HUMAN
NC score	0.020494 (rank : 795)	θ value	2.36792 (rank : 491)
Query Neighborhood Hits	613	Target Neighborhood Hits	734	Shared Neighborhood Hits	77
SwissProt Accessions	Q13106, Q8IVG7, Q8NAR0	Gene names	ZNF154, KIAA2003
Domain Architecture	No domain graphic available
Description	Zinc finger protein 154.

ZN493_HUMAN
NC score	0.020249 (rank : 796)	θ value	6.88961 (rank : 586)
Query Neighborhood Hits	613	Target Neighborhood Hits	754	Shared Neighborhood Hits	75
SwissProt Accessions	Q6ZR52, Q59GM3, Q6ZSF6, Q8N1Z6, Q8N965	Gene names	ZNF493
Domain Architecture	No domain graphic available
Description	Zinc finger protein 493.

ZN304_HUMAN
NC score	0.020248 (rank : 797)	θ value	8.99809 (rank : 609)
Query Neighborhood Hits	613	Target Neighborhood Hits	756	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HCX3	Gene names	ZNF304
Domain Architecture
Description	Zinc finger protein 304.

ZN583_MOUSE
NC score	0.020187 (rank : 798)	θ value	4.03905 (rank : 539)
Query Neighborhood Hits	613	Target Neighborhood Hits	774	Shared Neighborhood Hits	79
SwissProt Accessions	Q3V080, Q3V3L4	Gene names	Znf583, Zfp583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583.

ZN679_HUMAN
NC score	0.020166 (rank : 799)	θ value	8.99809 (rank : 612)
Query Neighborhood Hits	613	Target Neighborhood Hits	746	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IYX0	Gene names	ZNF679
Domain Architecture	No domain graphic available
Description	Zinc finger protein 679.

ZN419_HUMAN
NC score	0.020023 (rank : 800)	θ value	2.36792 (rank : 493)
Query Neighborhood Hits	613	Target Neighborhood Hits	745	Shared Neighborhood Hits	76
SwissProt Accessions	Q96HQ0, Q9H5P0	Gene names	ZNF419A, ZNF419
Domain Architecture	No domain graphic available
Description	Zinc finger protein 419A.

ZN559_HUMAN
NC score	0.019606 (rank : 801)	θ value	4.03905 (rank : 538)
Query Neighborhood Hits	613	Target Neighborhood Hits	746	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BR84	Gene names	ZNF559
Domain Architecture	No domain graphic available
Description	Zinc finger protein 559.

ZN561_HUMAN
NC score	0.019598 (rank : 802)	θ value	5.27518 (rank : 564)
Query Neighborhood Hits	613	Target Neighborhood Hits	734	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N587, Q6PJS0	Gene names	ZNF561
Domain Architecture	No domain graphic available
Description	Zinc finger protein 561.

GP158_HUMAN
NC score	0.019247 (rank : 803)	θ value	8.99809 (rank : 598)
Query Neighborhood Hits	613	Target Neighborhood Hits	221	Shared Neighborhood Hits	19
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

ZMYM6_HUMAN
NC score	0.019118 (rank : 804)	θ value	1.81305 (rank : 471)
Query Neighborhood Hits	613	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	O95789, Q96IY0	Gene names	ZMYM6, ZNF258
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 6 (Zinc finger protein 258).

TES_HUMAN
NC score	0.018850 (rank : 805)	θ value	3.0926 (rank : 512)
Query Neighborhood Hits	613	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UGI8, Q9GZQ1, Q9HAJ9	Gene names	TES
Domain Architecture
Description	Testin (TESS).

ZN684_HUMAN
NC score	0.018802 (rank : 806)	θ value	8.99809 (rank : 613)
Query Neighborhood Hits	613	Target Neighborhood Hits	731	Shared Neighborhood Hits	73
SwissProt Accessions	Q5T5D7, Q2NKY4	Gene names	ZNF684
Domain Architecture	No domain graphic available
Description	Zinc finger protein 684.

CTCF_MOUSE
NC score	0.018785 (rank : 807)	θ value	3.0926 (rank : 501)
Query Neighborhood Hits	613	Target Neighborhood Hits	796	Shared Neighborhood Hits	71
SwissProt Accessions	Q61164	Gene names	Ctcf
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

CTCF_HUMAN
NC score	0.018655 (rank : 808)	θ value	3.0926 (rank : 500)
Query Neighborhood Hits	613	Target Neighborhood Hits	764	Shared Neighborhood Hits	68
SwissProt Accessions	P49711	Gene names	CTCF
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

ZFN2B_HUMAN
NC score	0.018318 (rank : 809)	θ value	1.81305 (rank : 470)
Query Neighborhood Hits	613	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WV99, Q8NB98	Gene names	ZFAND2B
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 2B.

ZN394_HUMAN
NC score	0.017201 (rank : 810)	θ value	5.27518 (rank : 563)
Query Neighborhood Hits	613	Target Neighborhood Hits	752	Shared Neighborhood Hits	69
SwissProt Accessions	Q53GI3, Q6P5X9, Q8TB27, Q9HA37	Gene names	ZNF394
Domain Architecture	No domain graphic available
Description	Zinc finger protein 394.

FAM5A_MOUSE
NC score	0.015953 (rank : 811)	θ value	5.27518 (rank : 551)
Query Neighborhood Hits	613	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q920P3, Q80ZL2, Q812F0, Q8C1C9, Q920P4, Q9QXL0	Gene names	Fam5a, Brinp, Brinp1, Dbccr1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein homolog) (BMP/retinoic acid-inducible neural-specific protein 1).

FAM5A_HUMAN
NC score	0.015952 (rank : 812)	θ value	5.27518 (rank : 550)
Query Neighborhood Hits	613	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	O60477, Q6IPV6, Q6P1A0, Q8WU22	Gene names	FAM5A, DBC1, DBCCR1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein).

ZN581_HUMAN
NC score	0.015758 (rank : 813)	θ value	5.27518 (rank : 565)
Query Neighborhood Hits	613	Target Neighborhood Hits	699	Shared Neighborhood Hits	65
SwissProt Accessions	Q9P0T4	Gene names	ZNF581
Domain Architecture	No domain graphic available
Description	Zinc finger protein 581.

MSRX_MOUSE
NC score	0.015748 (rank : 814)	θ value	2.36792 (rank : 482)
Query Neighborhood Hits	613	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLC3	Gene names	Sepx1, Sepr
Domain Architecture
Description	Methionine-R-sulfoxide reductase (EC 1.8.4.-) (Selenoprotein X 1) (Selenoprotein R).

ZFN2B_MOUSE
NC score	0.015436 (rank : 815)	θ value	4.03905 (rank : 535)
Query Neighborhood Hits	613	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q91X58, Q9D0W4	Gene names	Zfand2b
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 2B.

ANR10_MOUSE
NC score	0.015079 (rank : 816)	θ value	8.99809 (rank : 589)
Query Neighborhood Hits	613	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

RSNB_MOUSE
NC score	0.013560 (rank : 817)	θ value	3.0926 (rank : 510)
Query Neighborhood Hits	613	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P86, Q9D286	Gene names	Retnlb, Fizz2
Domain Architecture
Description	Resistin-like beta precursor (RELMbeta) (Cysteine-rich secreted protein FIZZ2) (Cysteine-rich secreted protein A12-beta).

ARI2_HUMAN
NC score	0.011353 (rank : 818)	θ value	2.36792 (rank : 476)
Query Neighborhood Hits	613	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
NC score	0.010967 (rank : 819)	θ value	3.0926 (rank : 498)
Query Neighborhood Hits	613	Target Neighborhood Hits	106	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

ZFYV1_HUMAN
NC score	0.010857 (rank : 820)	θ value	2.36792 (rank : 490)
Query Neighborhood Hits	613	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HBF4, Q8WYX7, Q96K57, Q9BXP9, Q9HCI3	Gene names	ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (Tandem FYVE fingers-1) (SR3).

PARC_MOUSE
NC score	0.010764 (rank : 821)	θ value	5.27518 (rank : 556)
Query Neighborhood Hits	613	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

DCTN4_HUMAN
NC score	0.009878 (rank : 822)	θ value	6.88961 (rank : 571)
Query Neighborhood Hits	613	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJW0, Q8TAN8	Gene names	DCTN4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

DCTN4_MOUSE
NC score	0.009535 (rank : 823)	θ value	6.88961 (rank : 572)
Query Neighborhood Hits	613	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CBY8, Q923A0, Q9D4X0	Gene names	Dctn4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

UPAR_HUMAN
NC score	0.009337 (rank : 824)	θ value	5.27518 (rank : 559)
Query Neighborhood Hits	613	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q03405, Q12876, Q15845, Q16887, Q9NYC8, Q9UD69, Q9UEA6, Q9UM92, Q9UMV0	Gene names	PLAUR, MO3, UPAR
Domain Architecture
Description	Urokinase plasminogen activator surface receptor precursor (uPAR) (U- PAR) (Monocyte activation antigen Mo3) (CD87 antigen).

CRIS1_MOUSE
NC score	0.008783 (rank : 825)	θ value	2.36792 (rank : 478)
Query Neighborhood Hits	613	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q03401	Gene names	Crisp1, Aeg-1, Aeg1
Domain Architecture
Description	Cysteine-rich secretory protein 1 precursor (CRISP-1) (Acidic epididymal glycoprotein 1) (Sperm-coating glycoprotein 1) (SCP 1).

MARH3_MOUSE
NC score	0.008702 (rank : 826)	θ value	5.27518 (rank : 555)
Query Neighborhood Hits	613	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BRX9	Gene names	March3
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 3 (Membrane-associated RING-CH protein III) (MARCH-III).

CDCA7_HUMAN
NC score	0.008454 (rank : 827)	θ value	6.88961 (rank : 567)
Query Neighborhood Hits	613	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWT1, Q53EW5, Q580W9, Q658K4, Q658N4, Q8NBY9, Q96BV8, Q96SP5	Gene names	CDCA7, JPO1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated protein 7 (Protein JPO1).

MARH3_HUMAN
NC score	0.008451 (rank : 828)	θ value	5.27518 (rank : 554)
Query Neighborhood Hits	613	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UD3	Gene names	MARCH3, RNF173
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 3 (Membrane-associated RING-CH protein III) (MARCH-III) (RING finger protein 173).

UN84A_MOUSE
NC score	0.008139 (rank : 829)	θ value	4.03905 (rank : 534)
Query Neighborhood Hits	613	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D666, Q80SU8, Q8BZ99, Q99P23	Gene names	Unc84a, Sun1
Domain Architecture	No domain graphic available
Description	Sad1/unc-84 protein-like 1 (Unc-84 homolog A).

CRIS3_HUMAN
NC score	0.007501 (rank : 830)	θ value	8.99809 (rank : 593)
Query Neighborhood Hits	613	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	P54108, Q15512, Q5JW83, Q9H108	Gene names	CRISP3
Domain Architecture
Description	Cysteine-rich secretory protein 3 precursor (CRISP-3) (SGP28 protein).

CHD3_HUMAN
NC score	0.007413 (rank : 831)	θ value	3.0926 (rank : 499)
Query Neighborhood Hits	613	Target Neighborhood Hits	397	Shared Neighborhood Hits	20
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ZMY10_HUMAN
NC score	0.007167 (rank : 832)	θ value	5.27518 (rank : 561)
Query Neighborhood Hits	613	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	O75800, O14570, O75801, Q8N4R6, Q8NDN6	Gene names	ZMYND10, BLU
Domain Architecture
Description	Zinc finger MYND domain-containing protein 10 (BLu protein).

ENPP3_HUMAN
NC score	0.007086 (rank : 833)	θ value	4.03905 (rank : 523)
Query Neighborhood Hits	613	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	O14638	Gene names	ENPP3, PDNP3
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP 3) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (Phosphodiesterase I beta) (PD-Ibeta) (CD203c antigen) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

TS1R2_MOUSE
NC score	0.007073 (rank : 834)	θ value	1.81305 (rank : 468)
Query Neighborhood Hits	613	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

RIN1_MOUSE
NC score	0.006763 (rank : 835)	θ value	3.0926 (rank : 507)
Query Neighborhood Hits	613	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).

DGKB_HUMAN
NC score	0.005485 (rank : 836)	θ value	5.27518 (rank : 547)
Query Neighborhood Hits	613	Target Neighborhood Hits	238	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

V2R1B_MOUSE
NC score	0.005460 (rank : 837)	θ value	5.27518 (rank : 560)
Query Neighborhood Hits	613	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

UB7I4_MOUSE
NC score	0.004993 (rank : 838)	θ value	6.88961 (rank : 582)
Query Neighborhood Hits	613	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

DGKQ_HUMAN
NC score	0.004326 (rank : 839)	θ value	6.88961 (rank : 573)
Query Neighborhood Hits	613	Target Neighborhood Hits	131	Shared Neighborhood Hits	12
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

CTRO_MOUSE
NC score	0.003858 (rank : 840)	θ value	8.99809 (rank : 594)
Query Neighborhood Hits	613	Target Neighborhood Hits	2344	Shared Neighborhood Hits	64
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

RORB_MOUSE
NC score	0.003453 (rank : 841)	θ value	2.36792 (rank : 486)
Query Neighborhood Hits	613	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_HUMAN
NC score	0.003432 (rank : 842)	θ value	2.36792 (rank : 485)
Query Neighborhood Hits	613	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORA_MOUSE
NC score	0.003381 (rank : 843)	θ value	3.0926 (rank : 509)
Query Neighborhood Hits	613	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORA_HUMAN
NC score	0.003180 (rank : 844)	θ value	3.0926 (rank : 508)
Query Neighborhood Hits	613	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

KRHB1_HUMAN
NC score	0.002717 (rank : 845)	θ value	8.99809 (rank : 600)
Query Neighborhood Hits	613	Target Neighborhood Hits	461	Shared Neighborhood Hits	27
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

TRI36_MOUSE
NC score	0.002092 (rank : 846)	θ value	6.88961 (rank : 581)
Query Neighborhood Hits	613	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

WNT9B_MOUSE
NC score	0.001739 (rank : 847)	θ value	8.99809 (rank : 605)
Query Neighborhood Hits	613	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	O35468, Q8VI90	Gene names	Wnt9b, Wnt14b, Wnt15
Domain Architecture
Description	Protein Wnt-9b precursor (Wnt-15) (Wnt-14b).

ZN318_MOUSE
NC score	-0.000584 (rank : 848)	θ value	5.27518 (rank : 562)
Query Neighborhood Hits	613	Target Neighborhood Hits	642	Shared Neighborhood Hits	9
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

AHI1_HUMAN
NC score	-0.004578 (rank : 849)	θ value	3.0926 (rank : 497)
Query Neighborhood Hits	613	Target Neighborhood Hits	537	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).