Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : RIN1_MOUSE

For an explanation of this page, click here

RIN1_MOUSE
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RIN1_HUMAN
θ value	0 (rank : 1)	NC score	0.988784 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	52	Shared Neighborhood Hits	16
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

RIN1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).

RIN2_MOUSE
θ value	2.10232e-65 (rank : 3)	NC score	0.858053 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

RIN2_HUMAN
θ value	2.56992e-63 (rank : 4)	NC score	0.858584 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	50	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

RIN3_MOUSE
θ value	1.05066e-40 (rank : 5)	NC score	0.745800 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	239	Shared Neighborhood Hits	12
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIN3_HUMAN
θ value	3.4976e-36 (rank : 6)	NC score	0.753417 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RABX5_HUMAN
θ value	8.97725e-08 (rank : 7)	NC score	0.402122 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

RABX5_MOUSE
θ value	5.81887e-07 (rank : 8)	NC score	0.439083 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JM13, Q3UIW0	Gene names	Rabgef1, Rabex5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5).

CP007_MOUSE
θ value	8.40245e-06 (rank : 9)	NC score	0.290239 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	231	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

SOCS1_HUMAN
θ value	0.00134147 (rank : 10)	NC score	0.158736 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	O15524, O15097, Q9NSA7	Gene names	SOCS1, SSI1, TIP3
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3).

SOCS1_MOUSE
θ value	0.00134147 (rank : 11)	NC score	0.155605 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	O35716, O35960, Q3U3L0	Gene names	Socs1, Cish1, Ssi1
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1).

TENS4_HUMAN
θ value	0.0252991 (rank : 12)	NC score	0.143893 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	214	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

TENS4_MOUSE
θ value	0.0252991 (rank : 13)	NC score	0.134012 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	225	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

ANKS6_MOUSE
θ value	0.0736092 (rank : 14)	NC score	0.024550 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	435	Shared Neighborhood Hits	5
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ALEX_HUMAN
θ value	0.125558 (rank : 15)	NC score	0.049344 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	361	Shared Neighborhood Hits	8
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

TSC1_HUMAN
θ value	0.62314 (rank : 16)	NC score	0.020956 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	765	Shared Neighborhood Hits	6
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

RAI1_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.024390 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	360	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SLAP2_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.034142 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

MINT_MOUSE
θ value	2.36792 (rank : 19)	NC score	0.038707 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	1514	Shared Neighborhood Hits	20
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MUTYH_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.026463 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UIF7, Q15830, Q9UBP2, Q9UBS7, Q9UIF4, Q9UIF5, Q9UIF6	Gene names	MUTYH, MYH
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (hMYH).

TP53B_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.020377 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	413	Shared Neighborhood Hits	5
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ZN598_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.021814 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	339	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ANKS6_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.018526 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	411	Shared Neighborhood Hits	6
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

BSN_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.018678 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	2057	Shared Neighborhood Hits	19
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MYO15_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.009093 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	467	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOA6_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.019820 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	1076	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PCSK5_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.006763 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	613	Shared Neighborhood Hits	2
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

DOT1L_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.020127 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	660	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

RRBP1_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.005652 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	1306	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

L2GL2_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.010293 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P1M3, Q14521, Q9BR62	Gene names	LLGL2
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 2 (HGL).

TRIM8_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.006062 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	674	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

CADH2_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.002211 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	P15116, Q64260	Gene names	Cdh2
Domain Architecture
Description	Cadherin-2 precursor (Neural-cadherin) (N-cadherin) (CDw325 antigen).

EDG4_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.004480 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	461	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JL06	Gene names	Edg4, Lpa2
Domain Architecture
Description	Lysophosphatidic acid receptor Edg-4 (LPA receptor 2) (LPA-2).

HSH2D_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.042086 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

MYBB_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.010477 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

SYNJ1_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.008467 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	516	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TRPM6_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.007586 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TSHR_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.006491 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	554	Shared Neighborhood Hits	3
SwissProt Accessions	P47750, Q9D697	Gene names	Tshr
Domain Architecture
Description	Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormone receptor).

ZN683_HUMAN
θ value	6.88961 (rank : 39)	NC score	-0.000665 (rank : 48)
Query Neighborhood Hits	45	Target Neighborhood Hits	750	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZ20, Q5T141, Q5T146, Q5T147, Q5T149, Q8NEN4	Gene names	ZNF683
Domain Architecture	No domain graphic available
Description	Zinc finger protein 683.

CAC1B_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.003853 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	351	Shared Neighborhood Hits	5
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

EPC1_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.008780 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C9X6, Q9Z299	Gene names	Epc1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

NFM_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.001451 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	1159	Shared Neighborhood Hits	6
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

TCAL4_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.010425 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EI5, Q8WY12, Q9H2H1, Q9H775	Gene names	TCEAL4
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 4 (TCEA-like protein 4) (Transcription elongation factor S-II protein-like 4).

TSHR_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.005491 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	596	Shared Neighborhood Hits	4
SwissProt Accessions	P16473	Gene names	TSHR, LGR3
Domain Architecture
Description	Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormone receptor).

TULP4_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.009126 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

ALS2_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.060753 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

ALS2_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.059971 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	111	Shared Neighborhood Hits	7
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

CP007_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.055948 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	85	Shared Neighborhood Hits	1
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).

Hits sorted by NC score

RIN1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).

RIN1_HUMAN
NC score	0.988784 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	52	Shared Neighborhood Hits	16
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

RIN2_HUMAN
NC score	0.858584 (rank : 3)	θ value	2.56992e-63 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	50	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

RIN2_MOUSE
NC score	0.858053 (rank : 4)	θ value	2.10232e-65 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D684, Q99K06	Gene names	Rin2
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2).

RIN3_HUMAN
NC score	0.753417 (rank : 5)	θ value	3.4976e-36 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	227	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RIN3_MOUSE
NC score	0.745800 (rank : 6)	θ value	1.05066e-40 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	239	Shared Neighborhood Hits	12
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

RABX5_MOUSE
NC score	0.439083 (rank : 7)	θ value	5.81887e-07 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JM13, Q3UIW0	Gene names	Rabgef1, Rabex5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5).

RABX5_HUMAN
NC score	0.402122 (rank : 8)	θ value	8.97725e-08 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

CP007_MOUSE
NC score	0.290239 (rank : 9)	θ value	8.40245e-06 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	231	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

SOCS1_HUMAN
NC score	0.158736 (rank : 10)	θ value	0.00134147 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	O15524, O15097, Q9NSA7	Gene names	SOCS1, SSI1, TIP3
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3).

SOCS1_MOUSE
NC score	0.155605 (rank : 11)	θ value	0.00134147 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	82	Shared Neighborhood Hits	8
SwissProt Accessions	O35716, O35960, Q3U3L0	Gene names	Socs1, Cish1, Ssi1
Domain Architecture
Description	Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1).

TENS4_HUMAN
NC score	0.143893 (rank : 12)	θ value	0.0252991 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	214	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

TENS4_MOUSE
NC score	0.134012 (rank : 13)	θ value	0.0252991 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	225	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

ALS2_HUMAN
NC score	0.060753 (rank : 14)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

ALS2_MOUSE
NC score	0.059971 (rank : 15)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	111	Shared Neighborhood Hits	7
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

CP007_HUMAN
NC score	0.055948 (rank : 16)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	45	Target Neighborhood Hits	85	Shared Neighborhood Hits	1
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).

ALEX_HUMAN
NC score	0.049344 (rank : 17)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	361	Shared Neighborhood Hits	8
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

HSH2D_MOUSE
NC score	0.042086 (rank : 18)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

MINT_MOUSE
NC score	0.038707 (rank : 19)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	1514	Shared Neighborhood Hits	20
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SLAP2_MOUSE
NC score	0.034142 (rank : 20)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4L0, Q3UU74, Q8C0K2, Q8VI42, Q9D1Z9	Gene names	Sla2
Domain Architecture
Description	Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2).

MUTYH_HUMAN
NC score	0.026463 (rank : 21)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UIF7, Q15830, Q9UBP2, Q9UBS7, Q9UIF4, Q9UIF5, Q9UIF6	Gene names	MUTYH, MYH
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (hMYH).

ANKS6_MOUSE
NC score	0.024550 (rank : 22)	θ value	0.0736092 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	435	Shared Neighborhood Hits	5
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

RAI1_HUMAN
NC score	0.024390 (rank : 23)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	360	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ZN598_HUMAN
NC score	0.021814 (rank : 24)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	339	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

TSC1_HUMAN
NC score	0.020956 (rank : 25)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	765	Shared Neighborhood Hits	6
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TP53B_HUMAN
NC score	0.020377 (rank : 26)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	413	Shared Neighborhood Hits	5
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

DOT1L_HUMAN
NC score	0.020127 (rank : 27)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	660	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

NCOA6_MOUSE
NC score	0.019820 (rank : 28)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	1076	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

BSN_MOUSE
NC score	0.018678 (rank : 29)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	2057	Shared Neighborhood Hits	19
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ANKS6_HUMAN
NC score	0.018526 (rank : 30)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	411	Shared Neighborhood Hits	6
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

MYBB_HUMAN
NC score	0.010477 (rank : 31)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

TCAL4_HUMAN
NC score	0.010425 (rank : 32)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EI5, Q8WY12, Q9H2H1, Q9H775	Gene names	TCEAL4
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 4 (TCEA-like protein 4) (Transcription elongation factor S-II protein-like 4).

L2GL2_HUMAN
NC score	0.010293 (rank : 33)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P1M3, Q14521, Q9BR62	Gene names	LLGL2
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 2 (HGL).

TULP4_MOUSE
NC score	0.009126 (rank : 34)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

MYO15_MOUSE
NC score	0.009093 (rank : 35)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	467	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

EPC1_MOUSE
NC score	0.008780 (rank : 36)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C9X6, Q9Z299	Gene names	Epc1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

SYNJ1_MOUSE
NC score	0.008467 (rank : 37)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	516	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TRPM6_HUMAN
NC score	0.007586 (rank : 38)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

PCSK5_MOUSE
NC score	0.006763 (rank : 39)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	613	Shared Neighborhood Hits	2
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TSHR_MOUSE
NC score	0.006491 (rank : 40)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	554	Shared Neighborhood Hits	3
SwissProt Accessions	P47750, Q9D697	Gene names	Tshr
Domain Architecture
Description	Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormone receptor).

TRIM8_MOUSE
NC score	0.006062 (rank : 41)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	674	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

RRBP1_HUMAN
NC score	0.005652 (rank : 42)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	1306	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

TSHR_HUMAN
NC score	0.005491 (rank : 43)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	596	Shared Neighborhood Hits	4
SwissProt Accessions	P16473	Gene names	TSHR, LGR3
Domain Architecture
Description	Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormone receptor).

EDG4_MOUSE
NC score	0.004480 (rank : 44)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	461	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JL06	Gene names	Edg4, Lpa2
Domain Architecture
Description	Lysophosphatidic acid receptor Edg-4 (LPA receptor 2) (LPA-2).

CAC1B_MOUSE
NC score	0.003853 (rank : 45)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	351	Shared Neighborhood Hits	5
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CADH2_MOUSE
NC score	0.002211 (rank : 46)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	P15116, Q64260	Gene names	Cdh2
Domain Architecture
Description	Cadherin-2 precursor (Neural-cadherin) (N-cadherin) (CDw325 antigen).

NFM_MOUSE
NC score	0.001451 (rank : 47)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	1159	Shared Neighborhood Hits	6
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

ZN683_HUMAN
NC score	-0.000665 (rank : 48)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	750	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZ20, Q5T141, Q5T146, Q5T147, Q5T149, Q8NEN4	Gene names	ZNF683
Domain Architecture	No domain graphic available
Description	Zinc finger protein 683.