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Network neighborhood for query Sequence : ANKS6_MOUSE

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ANKS6_MOUSE
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ANKS6_HUMAN
θ value	0 (rank : 1)	NC score	0.989279 (rank : 2)
Query Neighborhood Hits	435	Target Neighborhood Hits	411	Shared Neighborhood Hits	347
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANKS6_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	435	Target Neighborhood Hits	435	Shared Neighborhood Hits	435
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR50_HUMAN
θ value	1.3722e-40 (rank : 3)	NC score	0.928363 (rank : 3)
Query Neighborhood Hits	435	Target Neighborhood Hits	361	Shared Neighborhood Hits	302
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANK1_MOUSE
θ value	4.00176e-32 (rank : 4)	NC score	0.897453 (rank : 12)
Query Neighborhood Hits	435	Target Neighborhood Hits	430	Shared Neighborhood Hits	298
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK1_HUMAN
θ value	6.82597e-32 (rank : 5)	NC score	0.899453 (rank : 10)
Query Neighborhood Hits	435	Target Neighborhood Hits	416	Shared Neighborhood Hits	298
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK3_HUMAN
θ value	4.89182e-30 (rank : 6)	NC score	0.886865 (rank : 23)
Query Neighborhood Hits	435	Target Neighborhood Hits	853	Shared Neighborhood Hits	318
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANKK1_HUMAN
θ value	1.57365e-28 (rank : 7)	NC score	0.584208 (rank : 212)
Query Neighborhood Hits	435	Target Neighborhood Hits	1075	Shared Neighborhood Hits	295
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANK2_HUMAN
θ value	7.80994e-28 (rank : 8)	NC score	0.834888 (rank : 89)
Query Neighborhood Hits	435	Target Neighborhood Hits	1615	Shared Neighborhood Hits	352
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANKK1_MOUSE
θ value	6.84181e-24 (rank : 9)	NC score	0.566865 (rank : 216)
Query Neighborhood Hits	435	Target Neighborhood Hits	1072	Shared Neighborhood Hits	291
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANR44_HUMAN
θ value	1.16704e-23 (rank : 10)	NC score	0.897688 (rank : 11)
Query Neighborhood Hits	435	Target Neighborhood Hits	318	Shared Neighborhood Hits	297
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

DAPK1_MOUSE
θ value	3.39556e-23 (rank : 11)	NC score	0.410723 (rank : 260)
Query Neighborhood Hits	435	Target Neighborhood Hits	1138	Shared Neighborhood Hits	295
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

ANR29_HUMAN
θ value	1.42661e-21 (rank : 12)	NC score	0.928194 (rank : 4)
Query Neighborhood Hits	435	Target Neighborhood Hits	294	Shared Neighborhood Hits	289
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANR28_MOUSE
θ value	1.86321e-21 (rank : 13)	NC score	0.894993 (rank : 14)
Query Neighborhood Hits	435	Target Neighborhood Hits	314	Shared Neighborhood Hits	294
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

DAPK1_HUMAN
θ value	4.15078e-21 (rank : 14)	NC score	0.401130 (rank : 261)
Query Neighborhood Hits	435	Target Neighborhood Hits	1130	Shared Neighborhood Hits	291
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

TNI3K_HUMAN
θ value	1.5773e-20 (rank : 15)	NC score	0.457273 (rank : 247)
Query Neighborhood Hits	435	Target Neighborhood Hits	1084	Shared Neighborhood Hits	297
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANR28_HUMAN
θ value	2.06002e-20 (rank : 16)	NC score	0.893964 (rank : 16)
Query Neighborhood Hits	435	Target Neighborhood Hits	314	Shared Neighborhood Hits	294
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR52_MOUSE
θ value	2.06002e-20 (rank : 17)	NC score	0.889324 (rank : 20)
Query Neighborhood Hits	435	Target Neighborhood Hits	318	Shared Neighborhood Hits	296
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
θ value	1.33526e-19 (rank : 18)	NC score	0.888567 (rank : 21)
Query Neighborhood Hits	435	Target Neighborhood Hits	322	Shared Neighborhood Hits	296
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

TNI3K_MOUSE
θ value	8.65492e-19 (rank : 19)	NC score	0.451844 (rank : 250)
Query Neighborhood Hits	435	Target Neighborhood Hits	1079	Shared Neighborhood Hits	296
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNKS1_HUMAN
θ value	8.65492e-19 (rank : 20)	NC score	0.891614 (rank : 18)
Query Neighborhood Hits	435	Target Neighborhood Hits	477	Shared Neighborhood Hits	322
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

RIPK4_HUMAN
θ value	1.13037e-18 (rank : 21)	NC score	0.568506 (rank : 215)
Query Neighborhood Hits	435	Target Neighborhood Hits	1094	Shared Neighborhood Hits	301
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ASB2_MOUSE
θ value	1.92812e-18 (rank : 22)	NC score	0.884863 (rank : 26)
Query Neighborhood Hits	435	Target Neighborhood Hits	321	Shared Neighborhood Hits	290
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

TNKS2_HUMAN
θ value	7.32683e-18 (rank : 23)	NC score	0.891487 (rank : 19)
Query Neighborhood Hits	435	Target Neighborhood Hits	361	Shared Neighborhood Hits	304
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

FANK1_HUMAN
θ value	1.63225e-17 (rank : 24)	NC score	0.901928 (rank : 8)
Query Neighborhood Hits	435	Target Neighborhood Hits	326	Shared Neighborhood Hits	284
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

RN5A_MOUSE
θ value	2.7842e-17 (rank : 25)	NC score	0.795765 (rank : 127)
Query Neighborhood Hits	435	Target Neighborhood Hits	899	Shared Neighborhood Hits	297
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

FANK1_MOUSE
θ value	3.63628e-17 (rank : 26)	NC score	0.900927 (rank : 9)
Query Neighborhood Hits	435	Target Neighborhood Hits	325	Shared Neighborhood Hits	280
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANKS3_MOUSE
θ value	1.058e-16 (rank : 27)	NC score	0.886714 (rank : 24)
Query Neighborhood Hits	435	Target Neighborhood Hits	355	Shared Neighborhood Hits	287
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB2_HUMAN
θ value	1.80466e-16 (rank : 28)	NC score	0.886518 (rank : 25)
Query Neighborhood Hits	435	Target Neighborhood Hits	309	Shared Neighborhood Hits	287
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB14_MOUSE
θ value	2.35696e-16 (rank : 29)	NC score	0.855768 (rank : 56)
Query Neighborhood Hits	435	Target Neighborhood Hits	293	Shared Neighborhood Hits	277
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB3_HUMAN
θ value	4.02038e-16 (rank : 30)	NC score	0.895099 (rank : 13)
Query Neighborhood Hits	435	Target Neighborhood Hits	316	Shared Neighborhood Hits	291
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANKS3_HUMAN
θ value	5.25075e-16 (rank : 31)	NC score	0.882511 (rank : 29)
Query Neighborhood Hits	435	Target Neighborhood Hits	355	Shared Neighborhood Hits	288
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

CSKI1_HUMAN
θ value	5.25075e-16 (rank : 32)	NC score	0.826338 (rank : 103)
Query Neighborhood Hits	435	Target Neighborhood Hits	997	Shared Neighborhood Hits	341
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MYPT1_MOUSE
θ value	5.25075e-16 (rank : 33)	NC score	0.857217 (rank : 54)
Query Neighborhood Hits	435	Target Neighborhood Hits	539	Shared Neighborhood Hits	295
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

CSKI1_MOUSE
θ value	6.85773e-16 (rank : 34)	NC score	0.825115 (rank : 104)
Query Neighborhood Hits	435	Target Neighborhood Hits	1031	Shared Neighborhood Hits	345
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MYPT1_HUMAN
θ value	8.95645e-16 (rank : 35)	NC score	0.837201 (rank : 85)
Query Neighborhood Hits	435	Target Neighborhood Hits	723	Shared Neighborhood Hits	292
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

TRPA1_MOUSE
θ value	8.95645e-16 (rank : 36)	NC score	0.870100 (rank : 42)
Query Neighborhood Hits	435	Target Neighborhood Hits	343	Shared Neighborhood Hits	291
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

MIB1_HUMAN
θ value	1.52774e-15 (rank : 37)	NC score	0.845862 (rank : 76)
Query Neighborhood Hits	435	Target Neighborhood Hits	470	Shared Neighborhood Hits	292
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	1.52774e-15 (rank : 38)	NC score	0.845226 (rank : 78)
Query Neighborhood Hits	435	Target Neighborhood Hits	471	Shared Neighborhood Hits	292
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

INVS_HUMAN
θ value	5.8054e-15 (rank : 39)	NC score	0.884400 (rank : 28)
Query Neighborhood Hits	435	Target Neighborhood Hits	455	Shared Neighborhood Hits	300
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ANKR6_HUMAN
θ value	7.58209e-15 (rank : 40)	NC score	0.892547 (rank : 17)
Query Neighborhood Hits	435	Target Neighborhood Hits	439	Shared Neighborhood Hits	288
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANKS1_HUMAN
θ value	7.58209e-15 (rank : 41)	NC score	0.854610 (rank : 60)
Query Neighborhood Hits	435	Target Neighborhood Hits	438	Shared Neighborhood Hits	310
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANR16_HUMAN
θ value	9.90251e-15 (rank : 42)	NC score	0.906991 (rank : 5)
Query Neighborhood Hits	435	Target Neighborhood Hits	286	Shared Neighborhood Hits	278
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ASB3_MOUSE
θ value	9.90251e-15 (rank : 43)	NC score	0.893992 (rank : 15)
Query Neighborhood Hits	435	Target Neighborhood Hits	316	Shared Neighborhood Hits	291
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

INVS_MOUSE
θ value	9.90251e-15 (rank : 44)	NC score	0.876498 (rank : 34)
Query Neighborhood Hits	435	Target Neighborhood Hits	609	Shared Neighborhood Hits	307
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANR23_MOUSE
θ value	1.29331e-14 (rank : 45)	NC score	0.880256 (rank : 31)
Query Neighborhood Hits	435	Target Neighborhood Hits	296	Shared Neighborhood Hits	283
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

RAI14_HUMAN
θ value	1.29331e-14 (rank : 46)	NC score	0.657671 (rank : 188)
Query Neighborhood Hits	435	Target Neighborhood Hits	1367	Shared Neighborhood Hits	312
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

TRPA1_HUMAN
θ value	2.20605e-14 (rank : 47)	NC score	0.869241 (rank : 43)
Query Neighborhood Hits	435	Target Neighborhood Hits	339	Shared Neighborhood Hits	294
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

RAI14_MOUSE
θ value	2.88119e-14 (rank : 48)	NC score	0.623737 (rank : 198)
Query Neighborhood Hits	435	Target Neighborhood Hits	1505	Shared Neighborhood Hits	313
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

PSD10_HUMAN
θ value	4.91457e-14 (rank : 49)	NC score	0.903016 (rank : 6)
Query Neighborhood Hits	435	Target Neighborhood Hits	301	Shared Neighborhood Hits	287
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

MYPT2_HUMAN
θ value	6.41864e-14 (rank : 50)	NC score	0.835433 (rank : 87)
Query Neighborhood Hits	435	Target Neighborhood Hits	707	Shared Neighborhood Hits	295
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

CSKI2_MOUSE
θ value	1.09485e-13 (rank : 51)	NC score	0.833672 (rank : 91)
Query Neighborhood Hits	435	Target Neighborhood Hits	812	Shared Neighborhood Hits	333
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANKS1_MOUSE
θ value	1.42992e-13 (rank : 52)	NC score	0.843609 (rank : 79)
Query Neighborhood Hits	435	Target Neighborhood Hits	453	Shared Neighborhood Hits	306
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

PSD10_MOUSE
θ value	1.42992e-13 (rank : 53)	NC score	0.902266 (rank : 7)
Query Neighborhood Hits	435	Target Neighborhood Hits	293	Shared Neighborhood Hits	287
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

RN5A_HUMAN
θ value	1.42992e-13 (rank : 54)	NC score	0.841652 (rank : 81)
Query Neighborhood Hits	435	Target Neighborhood Hits	608	Shared Neighborhood Hits	284
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASB10_MOUSE
θ value	2.43908e-13 (rank : 55)	NC score	0.874271 (rank : 37)
Query Neighborhood Hits	435	Target Neighborhood Hits	301	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

CSKI2_HUMAN
θ value	4.16044e-13 (rank : 56)	NC score	0.831910 (rank : 93)
Query Neighborhood Hits	435	Target Neighborhood Hits	747	Shared Neighborhood Hits	331
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANR23_HUMAN
θ value	1.2105e-12 (rank : 57)	NC score	0.874781 (rank : 35)
Query Neighborhood Hits	435	Target Neighborhood Hits	291	Shared Neighborhood Hits	282
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

MPP8_HUMAN
θ value	1.58096e-12 (rank : 58)	NC score	0.708421 (rank : 173)
Query Neighborhood Hits	435	Target Neighborhood Hits	948	Shared Neighborhood Hits	268
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CTTB2_HUMAN
θ value	2.0648e-12 (rank : 59)	NC score	0.761092 (rank : 145)
Query Neighborhood Hits	435	Target Neighborhood Hits	1061	Shared Neighborhood Hits	310
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

PP16A_MOUSE
θ value	2.0648e-12 (rank : 60)	NC score	0.858427 (rank : 52)
Query Neighborhood Hits	435	Target Neighborhood Hits	318	Shared Neighborhood Hits	282
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ASB7_MOUSE
θ value	3.52202e-12 (rank : 61)	NC score	0.881062 (rank : 30)
Query Neighborhood Hits	435	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

BARD1_HUMAN
θ value	4.59992e-12 (rank : 62)	NC score	0.822945 (rank : 106)
Query Neighborhood Hits	435	Target Neighborhood Hits	427	Shared Neighborhood Hits	289
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

GABP2_HUMAN
θ value	7.84624e-12 (rank : 63)	NC score	0.871807 (rank : 40)
Query Neighborhood Hits	435	Target Neighborhood Hits	454	Shared Neighborhood Hits	293
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

PP16B_HUMAN
θ value	1.02475e-11 (rank : 64)	NC score	0.847231 (rank : 74)
Query Neighborhood Hits	435	Target Neighborhood Hits	307	Shared Neighborhood Hits	282
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

ASB10_HUMAN
θ value	1.33837e-11 (rank : 65)	NC score	0.873625 (rank : 39)
Query Neighborhood Hits	435	Target Neighborhood Hits	291	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ANKR2_MOUSE
θ value	1.74796e-11 (rank : 66)	NC score	0.876801 (rank : 33)
Query Neighborhood Hits	435	Target Neighborhood Hits	312	Shared Neighborhood Hits	285
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ASZ1_HUMAN
θ value	1.74796e-11 (rank : 67)	NC score	0.862787 (rank : 51)
Query Neighborhood Hits	435	Target Neighborhood Hits	341	Shared Neighborhood Hits	274
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

BARD1_MOUSE
θ value	1.74796e-11 (rank : 68)	NC score	0.821476 (rank : 108)
Query Neighborhood Hits	435	Target Neighborhood Hits	411	Shared Neighborhood Hits	285
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ASB7_HUMAN
θ value	2.28291e-11 (rank : 69)	NC score	0.879672 (rank : 32)
Query Neighborhood Hits	435	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASZ1_MOUSE
θ value	2.28291e-11 (rank : 70)	NC score	0.865459 (rank : 47)
Query Neighborhood Hits	435	Target Neighborhood Hits	319	Shared Neighborhood Hits	276
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

GABP2_MOUSE
θ value	2.28291e-11 (rank : 71)	NC score	0.873696 (rank : 38)
Query Neighborhood Hits	435	Target Neighborhood Hits	429	Shared Neighborhood Hits	294
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

POT15_HUMAN
θ value	2.28291e-11 (rank : 72)	NC score	0.744036 (rank : 156)
Query Neighborhood Hits	435	Target Neighborhood Hits	893	Shared Neighborhood Hits	294
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

PP16B_MOUSE
θ value	2.28291e-11 (rank : 73)	NC score	0.845785 (rank : 77)
Query Neighborhood Hits	435	Target Neighborhood Hits	302	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANKR2_HUMAN
θ value	3.89403e-11 (rank : 74)	NC score	0.874764 (rank : 36)
Query Neighborhood Hits	435	Target Neighborhood Hits	321	Shared Neighborhood Hits	285
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR39_HUMAN
θ value	3.89403e-11 (rank : 75)	NC score	0.887349 (rank : 22)
Query Neighborhood Hits	435	Target Neighborhood Hits	285	Shared Neighborhood Hits	277
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB12_MOUSE
θ value	5.08577e-11 (rank : 76)	NC score	0.831037 (rank : 95)
Query Neighborhood Hits	435	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

PP16A_HUMAN
θ value	5.08577e-11 (rank : 77)	NC score	0.847816 (rank : 72)
Query Neighborhood Hits	435	Target Neighborhood Hits	340	Shared Neighborhood Hits	280
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ANR11_HUMAN
θ value	6.64225e-11 (rank : 78)	NC score	0.763858 (rank : 143)
Query Neighborhood Hits	435	Target Neighborhood Hits	1289	Shared Neighborhood Hits	318
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR12_HUMAN
θ value	6.64225e-11 (rank : 79)	NC score	0.733674 (rank : 161)
Query Neighborhood Hits	435	Target Neighborhood Hits	1081	Shared Neighborhood Hits	293
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR39_MOUSE
θ value	6.64225e-11 (rank : 80)	NC score	0.884765 (rank : 27)
Query Neighborhood Hits	435	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB16_MOUSE
θ value	6.64225e-11 (rank : 81)	NC score	0.842537 (rank : 80)
Query Neighborhood Hits	435	Target Neighborhood Hits	306	Shared Neighborhood Hits	275
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

CLPB_MOUSE
θ value	6.64225e-11 (rank : 82)	NC score	0.740884 (rank : 158)
Query Neighborhood Hits	435	Target Neighborhood Hits	289	Shared Neighborhood Hits	250
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

GABP3_MOUSE
θ value	8.67504e-11 (rank : 83)	NC score	0.870484 (rank : 41)
Query Neighborhood Hits	435	Target Neighborhood Hits	330	Shared Neighborhood Hits	279
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

RFXK_HUMAN
θ value	1.133e-10 (rank : 84)	NC score	0.849657 (rank : 69)
Query Neighborhood Hits	435	Target Neighborhood Hits	282	Shared Neighborhood Hits	264
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

UACA_MOUSE
θ value	1.47974e-10 (rank : 85)	NC score	0.494407 (rank : 237)
Query Neighborhood Hits	435	Target Neighborhood Hits	1620	Shared Neighborhood Hits	303
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ANR21_HUMAN
θ value	1.9326e-10 (rank : 86)	NC score	0.742361 (rank : 157)
Query Neighborhood Hits	435	Target Neighborhood Hits	864	Shared Neighborhood Hits	295
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANR35_HUMAN
θ value	1.9326e-10 (rank : 87)	NC score	0.803181 (rank : 120)
Query Neighborhood Hits	435	Target Neighborhood Hits	784	Shared Neighborhood Hits	297
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASB11_MOUSE
θ value	2.52405e-10 (rank : 88)	NC score	0.821344 (rank : 109)
Query Neighborhood Hits	435	Target Neighborhood Hits	271	Shared Neighborhood Hits	257
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB15_HUMAN
θ value	2.52405e-10 (rank : 89)	NC score	0.854146 (rank : 62)
Query Neighborhood Hits	435	Target Neighborhood Hits	305	Shared Neighborhood Hits	276
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB1_MOUSE
θ value	2.52405e-10 (rank : 90)	NC score	0.831771 (rank : 94)
Query Neighborhood Hits	435	Target Neighborhood Hits	292	Shared Neighborhood Hits	278
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANKR5_MOUSE
θ value	3.29651e-10 (rank : 91)	NC score	0.855072 (rank : 58)
Query Neighborhood Hits	435	Target Neighborhood Hits	298	Shared Neighborhood Hits	281
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANRA2_HUMAN
θ value	3.29651e-10 (rank : 92)	NC score	0.853152 (rank : 64)
Query Neighborhood Hits	435	Target Neighborhood Hits	288	Shared Neighborhood Hits	281
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANRA2_MOUSE
θ value	3.29651e-10 (rank : 93)	NC score	0.851514 (rank : 66)
Query Neighborhood Hits	435	Target Neighborhood Hits	287	Shared Neighborhood Hits	280
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB1_HUMAN
θ value	3.29651e-10 (rank : 94)	NC score	0.834500 (rank : 90)
Query Neighborhood Hits	435	Target Neighborhood Hits	291	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR47_HUMAN
θ value	4.30538e-10 (rank : 95)	NC score	0.753302 (rank : 152)
Query Neighborhood Hits	435	Target Neighborhood Hits	369	Shared Neighborhood Hits	261
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

UACA_HUMAN
θ value	4.30538e-10 (rank : 96)	NC score	0.519839 (rank : 227)
Query Neighborhood Hits	435	Target Neighborhood Hits	1622	Shared Neighborhood Hits	304
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

EHMT1_HUMAN
θ value	5.62301e-10 (rank : 97)	NC score	0.813399 (rank : 113)
Query Neighborhood Hits	435	Target Neighborhood Hits	417	Shared Neighborhood Hits	299
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

IKBB_HUMAN
θ value	5.62301e-10 (rank : 98)	NC score	0.799133 (rank : 125)
Query Neighborhood Hits	435	Target Neighborhood Hits	284	Shared Neighborhood Hits	268
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

MIB2_HUMAN
θ value	5.62301e-10 (rank : 99)	NC score	0.829420 (rank : 98)
Query Neighborhood Hits	435	Target Neighborhood Hits	438	Shared Neighborhood Hits	287
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

AN30A_HUMAN
θ value	7.34386e-10 (rank : 100)	NC score	0.595455 (rank : 207)
Query Neighborhood Hits	435	Target Neighborhood Hits	1119	Shared Neighborhood Hits	288
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANKR5_HUMAN
θ value	7.34386e-10 (rank : 101)	NC score	0.854859 (rank : 59)
Query Neighborhood Hits	435	Target Neighborhood Hits	297	Shared Neighborhood Hits	280
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ASB11_HUMAN
θ value	7.34386e-10 (rank : 102)	NC score	0.819768 (rank : 110)
Query Neighborhood Hits	435	Target Neighborhood Hits	271	Shared Neighborhood Hits	259
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANKR1_HUMAN
θ value	9.59137e-10 (rank : 103)	NC score	0.866384 (rank : 45)
Query Neighborhood Hits	435	Target Neighborhood Hits	308	Shared Neighborhood Hits	279
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

MIB2_MOUSE
θ value	9.59137e-10 (rank : 104)	NC score	0.828382 (rank : 100)
Query Neighborhood Hits	435	Target Neighborhood Hits	409	Shared Neighborhood Hits	280
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

NFKB1_MOUSE
θ value	9.59137e-10 (rank : 105)	NC score	0.727378 (rank : 164)
Query Neighborhood Hits	435	Target Neighborhood Hits	300	Shared Neighborhood Hits	265
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

ANFY1_HUMAN
θ value	1.25267e-09 (rank : 106)	NC score	0.780207 (rank : 134)
Query Neighborhood Hits	435	Target Neighborhood Hits	480	Shared Neighborhood Hits	286
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANKR1_MOUSE
θ value	1.25267e-09 (rank : 107)	NC score	0.863891 (rank : 50)
Query Neighborhood Hits	435	Target Neighborhood Hits	316	Shared Neighborhood Hits	285
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANKY2_MOUSE
θ value	1.25267e-09 (rank : 108)	NC score	0.771693 (rank : 137)
Query Neighborhood Hits	435	Target Neighborhood Hits	316	Shared Neighborhood Hits	261
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR47_MOUSE
θ value	1.25267e-09 (rank : 109)	NC score	0.773805 (rank : 136)
Query Neighborhood Hits	435	Target Neighborhood Hits	350	Shared Neighborhood Hits	263
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ABTB2_HUMAN
θ value	1.63604e-09 (rank : 110)	NC score	0.628194 (rank : 197)
Query Neighborhood Hits	435	Target Neighborhood Hits	391	Shared Neighborhood Hits	240
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

EHMT2_MOUSE
θ value	1.63604e-09 (rank : 111)	NC score	0.788285 (rank : 131)
Query Neighborhood Hits	435	Target Neighborhood Hits	750	Shared Neighborhood Hits	314
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

NOTC2_MOUSE
θ value	2.13673e-09 (rank : 112)	NC score	0.413429 (rank : 258)
Query Neighborhood Hits	435	Target Neighborhood Hits	1069	Shared Neighborhood Hits	298
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ANKR7_HUMAN
θ value	2.79066e-09 (rank : 113)	NC score	0.839707 (rank : 84)
Query Neighborhood Hits	435	Target Neighborhood Hits	286	Shared Neighborhood Hits	278
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

NFKB1_HUMAN
θ value	3.64472e-09 (rank : 114)	NC score	0.730545 (rank : 163)
Query Neighborhood Hits	435	Target Neighborhood Hits	306	Shared Neighborhood Hits	271
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ANFY1_MOUSE
θ value	4.76016e-09 (rank : 115)	NC score	0.780699 (rank : 133)
Query Neighborhood Hits	435	Target Neighborhood Hits	480	Shared Neighborhood Hits	293
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR42_HUMAN
θ value	4.76016e-09 (rank : 116)	NC score	0.867835 (rank : 44)
Query Neighborhood Hits	435	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB9_HUMAN
θ value	4.76016e-09 (rank : 117)	NC score	0.822030 (rank : 107)
Query Neighborhood Hits	435	Target Neighborhood Hits	267	Shared Neighborhood Hits	259
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

NOTC2_HUMAN
θ value	4.76016e-09 (rank : 118)	NC score	0.415921 (rank : 257)
Query Neighborhood Hits	435	Target Neighborhood Hits	1113	Shared Neighborhood Hits	302
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ANKY2_HUMAN
θ value	6.21693e-09 (rank : 119)	NC score	0.793027 (rank : 129)
Query Neighborhood Hits	435	Target Neighborhood Hits	306	Shared Neighborhood Hits	264
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

IKBB_MOUSE
θ value	6.21693e-09 (rank : 120)	NC score	0.800789 (rank : 123)
Query Neighborhood Hits	435	Target Neighborhood Hits	284	Shared Neighborhood Hits	273
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ZDH17_HUMAN
θ value	6.21693e-09 (rank : 121)	NC score	0.756946 (rank : 148)
Query Neighborhood Hits	435	Target Neighborhood Hits	334	Shared Neighborhood Hits	279
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

EHMT2_HUMAN
θ value	8.11959e-09 (rank : 122)	NC score	0.800730 (rank : 124)
Query Neighborhood Hits	435	Target Neighborhood Hits	498	Shared Neighborhood Hits	302
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

TEX14_MOUSE
θ value	1.06045e-08 (rank : 123)	NC score	0.419351 (rank : 254)
Query Neighborhood Hits	435	Target Neighborhood Hits	1333	Shared Neighborhood Hits	265
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

BCL3_HUMAN
θ value	1.38499e-08 (rank : 124)	NC score	0.853993 (rank : 63)
Query Neighborhood Hits	435	Target Neighborhood Hits	324	Shared Neighborhood Hits	285
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

BCL3_MOUSE
θ value	1.38499e-08 (rank : 125)	NC score	0.848940 (rank : 70)
Query Neighborhood Hits	435	Target Neighborhood Hits	388	Shared Neighborhood Hits	282
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

MTPN_HUMAN
θ value	1.38499e-08 (rank : 126)	NC score	0.864470 (rank : 49)
Query Neighborhood Hits	435	Target Neighborhood Hits	269	Shared Neighborhood Hits	268
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ZDH17_MOUSE
θ value	1.38499e-08 (rank : 127)	NC score	0.750778 (rank : 153)
Query Neighborhood Hits	435	Target Neighborhood Hits	328	Shared Neighborhood Hits	273
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANR49_HUMAN
θ value	1.80886e-08 (rank : 128)	NC score	0.855424 (rank : 57)
Query Neighborhood Hits	435	Target Neighborhood Hits	282	Shared Neighborhood Hits	276
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ASB15_MOUSE
θ value	1.80886e-08 (rank : 129)	NC score	0.840026 (rank : 83)
Query Neighborhood Hits	435	Target Neighborhood Hits	292	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

BCOR_MOUSE
θ value	1.80886e-08 (rank : 130)	NC score	0.746294 (rank : 154)
Query Neighborhood Hits	435	Target Neighborhood Hits	521	Shared Neighborhood Hits	290
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ABTB2_MOUSE
θ value	2.36244e-08 (rank : 131)	NC score	0.616584 (rank : 200)
Query Neighborhood Hits	435	Target Neighborhood Hits	414	Shared Neighborhood Hits	241
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

BCOR_HUMAN
θ value	2.36244e-08 (rank : 132)	NC score	0.736938 (rank : 160)
Query Neighborhood Hits	435	Target Neighborhood Hits	609	Shared Neighborhood Hits	289
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CDN2C_MOUSE
θ value	2.36244e-08 (rank : 133)	NC score	0.857251 (rank : 53)
Query Neighborhood Hits	435	Target Neighborhood Hits	270	Shared Neighborhood Hits	267
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

IKBE_MOUSE
θ value	2.36244e-08 (rank : 134)	NC score	0.823049 (rank : 105)
Query Neighborhood Hits	435	Target Neighborhood Hits	308	Shared Neighborhood Hits	272
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ANR15_HUMAN
θ value	3.08544e-08 (rank : 135)	NC score	0.770909 (rank : 138)
Query Neighborhood Hits	435	Target Neighborhood Hits	478	Shared Neighborhood Hits	277
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

CDN2C_HUMAN
θ value	3.08544e-08 (rank : 136)	NC score	0.854306 (rank : 61)
Query Neighborhood Hits	435	Target Neighborhood Hits	262	Shared Neighborhood Hits	261
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CDN2D_MOUSE
θ value	3.08544e-08 (rank : 137)	NC score	0.846330 (rank : 75)
Query Neighborhood Hits	435	Target Neighborhood Hits	267	Shared Neighborhood Hits	263
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

RFXK_MOUSE
θ value	3.08544e-08 (rank : 138)	NC score	0.840233 (rank : 82)
Query Neighborhood Hits	435	Target Neighborhood Hits	273	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

NOTC3_HUMAN
θ value	4.0297e-08 (rank : 139)	NC score	0.419105 (rank : 255)
Query Neighborhood Hits	435	Target Neighborhood Hits	1062	Shared Neighborhood Hits	298
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
θ value	4.0297e-08 (rank : 140)	NC score	0.455594 (rank : 248)
Query Neighborhood Hits	435	Target Neighborhood Hits	905	Shared Neighborhood Hits	289
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

POTE8_HUMAN
θ value	4.0297e-08 (rank : 141)	NC score	0.787807 (rank : 132)
Query Neighborhood Hits	435	Target Neighborhood Hits	337	Shared Neighborhood Hits	286
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

NOTC3_MOUSE
θ value	5.26297e-08 (rank : 142)	NC score	0.421490 (rank : 253)
Query Neighborhood Hits	435	Target Neighborhood Hits	975	Shared Neighborhood Hits	300
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ANR42_MOUSE
θ value	6.87365e-08 (rank : 143)	NC score	0.865848 (rank : 46)
Query Neighborhood Hits	435	Target Neighborhood Hits	334	Shared Neighborhood Hits	277
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR46_HUMAN
θ value	6.87365e-08 (rank : 144)	NC score	0.835989 (rank : 86)
Query Neighborhood Hits	435	Target Neighborhood Hits	281	Shared Neighborhood Hits	270
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

MTPN_MOUSE
θ value	6.87365e-08 (rank : 145)	NC score	0.865157 (rank : 48)
Query Neighborhood Hits	435	Target Neighborhood Hits	269	Shared Neighborhood Hits	268
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

CDN2D_HUMAN
θ value	8.97725e-08 (rank : 146)	NC score	0.851614 (rank : 65)
Query Neighborhood Hits	435	Target Neighborhood Hits	268	Shared Neighborhood Hits	267
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

NOTC4_MOUSE
θ value	8.97725e-08 (rank : 147)	NC score	0.461207 (rank : 245)
Query Neighborhood Hits	435	Target Neighborhood Hits	872	Shared Neighborhood Hits	286
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ASB12_HUMAN
θ value	1.17247e-07 (rank : 148)	NC score	0.829642 (rank : 97)
Query Neighborhood Hits	435	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

SHAN1_HUMAN
θ value	1.17247e-07 (rank : 149)	NC score	0.720099 (rank : 169)
Query Neighborhood Hits	435	Target Neighborhood Hits	1041	Shared Neighborhood Hits	320
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ZDH13_HUMAN
θ value	1.53129e-07 (rank : 150)	NC score	0.745144 (rank : 155)
Query Neighborhood Hits	435	Target Neighborhood Hits	322	Shared Neighborhood Hits	272
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ANR26_MOUSE
θ value	1.99992e-07 (rank : 151)	NC score	0.468907 (rank : 242)
Query Neighborhood Hits	435	Target Neighborhood Hits	1554	Shared Neighborhood Hits	300
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR46_MOUSE
θ value	2.61198e-07 (rank : 152)	NC score	0.828624 (rank : 99)
Query Neighborhood Hits	435	Target Neighborhood Hits	274	Shared Neighborhood Hits	263
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

NOTC1_HUMAN
θ value	2.61198e-07 (rank : 153)	NC score	0.416371 (rank : 256)
Query Neighborhood Hits	435	Target Neighborhood Hits	906	Shared Neighborhood Hits	288
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANR33_HUMAN
θ value	5.81887e-07 (rank : 154)	NC score	0.724478 (rank : 166)
Query Neighborhood Hits	435	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR49_MOUSE
θ value	7.59969e-07 (rank : 155)	NC score	0.856853 (rank : 55)
Query Neighborhood Hits	435	Target Neighborhood Hits	285	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ASB13_MOUSE
θ value	7.59969e-07 (rank : 156)	NC score	0.851082 (rank : 68)
Query Neighborhood Hits	435	Target Neighborhood Hits	293	Shared Neighborhood Hits	277
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

TRPV5_HUMAN
θ value	7.59969e-07 (rank : 157)	NC score	0.514002 (rank : 228)
Query Neighborhood Hits	435	Target Neighborhood Hits	261	Shared Neighborhood Hits	226
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ANR33_MOUSE
θ value	9.92553e-07 (rank : 158)	NC score	0.731184 (rank : 162)
Query Neighborhood Hits	435	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ASB13_HUMAN
θ value	9.92553e-07 (rank : 159)	NC score	0.851144 (rank : 67)
Query Neighborhood Hits	435	Target Neighborhood Hits	293	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

HECD1_HUMAN
θ value	9.92553e-07 (rank : 160)	NC score	0.621138 (rank : 199)
Query Neighborhood Hits	435	Target Neighborhood Hits	371	Shared Neighborhood Hits	268
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

IASPP_MOUSE
θ value	9.92553e-07 (rank : 161)	NC score	0.531951 (rank : 224)
Query Neighborhood Hits	435	Target Neighborhood Hits	1024	Shared Neighborhood Hits	280
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ASB16_HUMAN
θ value	1.29631e-06 (rank : 162)	NC score	0.834925 (rank : 88)
Query Neighborhood Hits	435	Target Neighborhood Hits	286	Shared Neighborhood Hits	266
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

IKBA_HUMAN
θ value	1.29631e-06 (rank : 163)	NC score	0.827721 (rank : 101)
Query Neighborhood Hits	435	Target Neighborhood Hits	280	Shared Neighborhood Hits	269
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

TRPV5_MOUSE
θ value	1.29631e-06 (rank : 164)	NC score	0.546547 (rank : 221)
Query Neighborhood Hits	435	Target Neighborhood Hits	278	Shared Neighborhood Hits	247
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

A20A2_HUMAN
θ value	1.69304e-06 (rank : 165)	NC score	0.669329 (rank : 182)
Query Neighborhood Hits	435	Target Neighborhood Hits	716	Shared Neighborhood Hits	285
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A3_HUMAN
θ value	1.69304e-06 (rank : 166)	NC score	0.670076 (rank : 181)
Query Neighborhood Hits	435	Target Neighborhood Hits	692	Shared Neighborhood Hits	282
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	1.69304e-06 (rank : 167)	NC score	0.665289 (rank : 186)
Query Neighborhood Hits	435	Target Neighborhood Hits	710	Shared Neighborhood Hits	282
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR19_HUMAN
θ value	1.69304e-06 (rank : 168)	NC score	0.774913 (rank : 135)
Query Neighborhood Hits	435	Target Neighborhood Hits	276	Shared Neighborhood Hits	266
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

TRPV6_MOUSE
θ value	1.69304e-06 (rank : 169)	NC score	0.596372 (rank : 206)
Query Neighborhood Hits	435	Target Neighborhood Hits	284	Shared Neighborhood Hits	255
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANR26_HUMAN
θ value	2.21117e-06 (rank : 170)	NC score	0.446880 (rank : 252)
Query Neighborhood Hits	435	Target Neighborhood Hits	1614	Shared Neighborhood Hits	304
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB5_HUMAN
θ value	2.21117e-06 (rank : 171)	NC score	0.813815 (rank : 112)
Query Neighborhood Hits	435	Target Neighborhood Hits	283	Shared Neighborhood Hits	269
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

CD2A1_MOUSE
θ value	2.21117e-06 (rank : 172)	NC score	0.720976 (rank : 168)
Query Neighborhood Hits	435	Target Neighborhood Hits	206	Shared Neighborhood Hits	203
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

ILK1_HUMAN
θ value	2.21117e-06 (rank : 173)	NC score	0.506349 (rank : 232)
Query Neighborhood Hits	435	Target Neighborhood Hits	857	Shared Neighborhood Hits	283
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	2.21117e-06 (rank : 174)	NC score	0.523976 (rank : 226)
Query Neighborhood Hits	435	Target Neighborhood Hits	848	Shared Neighborhood Hits	283
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

IKBA_MOUSE
θ value	2.88788e-06 (rank : 175)	NC score	0.815204 (rank : 111)
Query Neighborhood Hits	435	Target Neighborhood Hits	283	Shared Neighborhood Hits	270
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

PA2G6_HUMAN
θ value	2.88788e-06 (rank : 176)	NC score	0.827661 (rank : 102)
Query Neighborhood Hits	435	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ACBD6_MOUSE
θ value	3.77169e-06 (rank : 177)	NC score	0.812771 (rank : 114)
Query Neighborhood Hits	435	Target Neighborhood Hits	305	Shared Neighborhood Hits	283
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR25_HUMAN
θ value	3.77169e-06 (rank : 178)	NC score	0.721591 (rank : 167)
Query Neighborhood Hits	435	Target Neighborhood Hits	350	Shared Neighborhood Hits	269
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ZDH13_MOUSE
θ value	3.77169e-06 (rank : 179)	NC score	0.740047 (rank : 159)
Query Neighborhood Hits	435	Target Neighborhood Hits	329	Shared Neighborhood Hits	275
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

A20A1_HUMAN
θ value	4.92598e-06 (rank : 180)	NC score	0.667405 (rank : 185)
Query Neighborhood Hits	435	Target Neighborhood Hits	698	Shared Neighborhood Hits	279
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

ILK_MOUSE
θ value	4.92598e-06 (rank : 181)	NC score	0.503876 (rank : 235)
Query Neighborhood Hits	435	Target Neighborhood Hits	858	Shared Neighborhood Hits	283
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ACBD6_HUMAN
θ value	6.43352e-06 (rank : 182)	NC score	0.810944 (rank : 115)
Query Neighborhood Hits	435	Target Neighborhood Hits	304	Shared Neighborhood Hits	281
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR25_MOUSE
θ value	6.43352e-06 (rank : 183)	NC score	0.707289 (rank : 174)
Query Neighborhood Hits	435	Target Neighborhood Hits	398	Shared Neighborhood Hits	269
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

CENB1_HUMAN
θ value	6.43352e-06 (rank : 184)	NC score	0.554524 (rank : 218)
Query Neighborhood Hits	435	Target Neighborhood Hits	383	Shared Neighborhood Hits	258
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

ASPP2_HUMAN
θ value	8.40245e-06 (rank : 185)	NC score	0.585545 (rank : 211)
Query Neighborhood Hits	435	Target Neighborhood Hits	1156	Shared Neighborhood Hits	298
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CENB2_HUMAN
θ value	1.09739e-05 (rank : 186)	NC score	0.545738 (rank : 222)
Query Neighborhood Hits	435	Target Neighborhood Hits	425	Shared Neighborhood Hits	255
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

POT14_HUMAN
θ value	1.09739e-05 (rank : 187)	NC score	0.725041 (rank : 165)
Query Neighborhood Hits	435	Target Neighborhood Hits	403	Shared Neighborhood Hits	272
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ASB5_MOUSE
θ value	1.43324e-05 (rank : 188)	NC score	0.808596 (rank : 116)
Query Neighborhood Hits	435	Target Neighborhood Hits	266	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

OSBL1_HUMAN
θ value	1.43324e-05 (rank : 189)	NC score	0.668227 (rank : 183)
Query Neighborhood Hits	435	Target Neighborhood Hits	368	Shared Neighborhood Hits	278
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_MOUSE
θ value	1.43324e-05 (rank : 190)	NC score	0.655466 (rank : 189)
Query Neighborhood Hits	435	Target Neighborhood Hits	336	Shared Neighborhood Hits	279
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

AN36B_HUMAN
θ value	1.87187e-05 (rank : 191)	NC score	0.801375 (rank : 122)
Query Neighborhood Hits	435	Target Neighborhood Hits	294	Shared Neighborhood Hits	280
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANR38_HUMAN
θ value	1.87187e-05 (rank : 192)	NC score	0.698440 (rank : 175)
Query Neighborhood Hits	435	Target Neighborhood Hits	443	Shared Neighborhood Hits	248
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CLPB_HUMAN
θ value	1.87187e-05 (rank : 193)	NC score	0.648229 (rank : 191)
Query Neighborhood Hits	435	Target Neighborhood Hits	265	Shared Neighborhood Hits	236
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

IASPP_HUMAN
θ value	1.87187e-05 (rank : 194)	NC score	0.586655 (rank : 210)
Query Neighborhood Hits	435	Target Neighborhood Hits	688	Shared Neighborhood Hits	277
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NUD12_MOUSE
θ value	1.87187e-05 (rank : 195)	NC score	0.614094 (rank : 204)
Query Neighborhood Hits	435	Target Neighborhood Hits	243	Shared Neighborhood Hits	222
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ANS4B_MOUSE
θ value	2.44474e-05 (rank : 196)	NC score	0.757982 (rank : 146)
Query Neighborhood Hits	435	Target Neighborhood Hits	294	Shared Neighborhood Hits	256
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

PA2G6_MOUSE
θ value	2.44474e-05 (rank : 197)	NC score	0.830459 (rank : 96)
Query Neighborhood Hits	435	Target Neighborhood Hits	293	Shared Neighborhood Hits	281
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

CT086_HUMAN
θ value	3.19293e-05 (rank : 198)	NC score	0.833352 (rank : 92)
Query Neighborhood Hits	435	Target Neighborhood Hits	277	Shared Neighborhood Hits	269
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

TEX14_HUMAN
θ value	3.19293e-05 (rank : 199)	NC score	0.410965 (rank : 259)
Query Neighborhood Hits	435	Target Neighborhood Hits	1103	Shared Neighborhood Hits	255
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

IKBE_HUMAN
θ value	4.1701e-05 (rank : 200)	NC score	0.796479 (rank : 126)
Query Neighborhood Hits	435	Target Neighborhood Hits	288	Shared Neighborhood Hits	263
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ANR10_HUMAN
θ value	5.44631e-05 (rank : 201)	NC score	0.806738 (rank : 117)
Query Neighborhood Hits	435	Target Neighborhood Hits	289	Shared Neighborhood Hits	265
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR18_HUMAN
θ value	5.44631e-05 (rank : 202)	NC score	0.616217 (rank : 201)
Query Neighborhood Hits	435	Target Neighborhood Hits	1106	Shared Neighborhood Hits	280
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR40_HUMAN
θ value	5.44631e-05 (rank : 203)	NC score	0.638024 (rank : 194)
Query Neighborhood Hits	435	Target Neighborhood Hits	224	Shared Neighborhood Hits	202
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
θ value	7.1131e-05 (rank : 204)	NC score	0.635116 (rank : 195)
Query Neighborhood Hits	435	Target Neighborhood Hits	228	Shared Neighborhood Hits	206
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANS4B_HUMAN
θ value	7.1131e-05 (rank : 205)	NC score	0.767912 (rank : 141)
Query Neighborhood Hits	435	Target Neighborhood Hits	289	Shared Neighborhood Hits	260
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ASB6_MOUSE
θ value	7.1131e-05 (rank : 206)	NC score	0.753685 (rank : 151)
Query Neighborhood Hits	435	Target Neighborhood Hits	264	Shared Neighborhood Hits	246
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASB9_MOUSE
θ value	7.1131e-05 (rank : 207)	NC score	0.802909 (rank : 121)
Query Neighborhood Hits	435	Target Neighborhood Hits	257	Shared Neighborhood Hits	252
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ASPP1_HUMAN
θ value	7.1131e-05 (rank : 208)	NC score	0.568516 (rank : 214)
Query Neighborhood Hits	435	Target Neighborhood Hits	956	Shared Neighborhood Hits	283
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	7.1131e-05 (rank : 209)	NC score	0.551534 (rank : 220)
Query Neighborhood Hits	435	Target Neighborhood Hits	1244	Shared Neighborhood Hits	297
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CT012_MOUSE
θ value	7.1131e-05 (rank : 210)	NC score	0.505108 (rank : 234)
Query Neighborhood Hits	435	Target Neighborhood Hits	229	Shared Neighborhood Hits	182
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

USH1G_HUMAN
θ value	7.1131e-05 (rank : 211)	NC score	0.769450 (rank : 139)
Query Neighborhood Hits	435	Target Neighborhood Hits	267	Shared Neighborhood Hits	263
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	7.1131e-05 (rank : 212)	NC score	0.769362 (rank : 140)
Query Neighborhood Hits	435	Target Neighborhood Hits	271	Shared Neighborhood Hits	263
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ASB8_MOUSE
θ value	9.29e-05 (rank : 213)	NC score	0.847726 (rank : 73)
Query Neighborhood Hits	435	Target Neighborhood Hits	293	Shared Neighborhood Hits	275
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

POT22_HUMAN
θ value	9.29e-05 (rank : 214)	NC score	0.681717 (rank : 178)
Query Neighborhood Hits	435	Target Neighborhood Hits	266	Shared Neighborhood Hits	254
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

NUD12_HUMAN
θ value	0.000121331 (rank : 215)	NC score	0.582532 (rank : 213)
Query Neighborhood Hits	435	Target Neighborhood Hits	222	Shared Neighborhood Hits	202
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

TRPV6_HUMAN
θ value	0.000121331 (rank : 216)	NC score	0.505651 (rank : 233)
Query Neighborhood Hits	435	Target Neighborhood Hits	262	Shared Neighborhood Hits	228
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

OSTF1_HUMAN
θ value	0.000158464 (rank : 217)	NC score	0.639025 (rank : 193)
Query Neighborhood Hits	435	Target Neighborhood Hits	466	Shared Neighborhood Hits	257
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

OSTF1_MOUSE
θ value	0.000158464 (rank : 218)	NC score	0.655234 (rank : 190)
Query Neighborhood Hits	435	Target Neighborhood Hits	467	Shared Neighborhood Hits	258
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ASB8_HUMAN
θ value	0.00020696 (rank : 219)	NC score	0.848099 (rank : 71)
Query Neighborhood Hits	435	Target Neighborhood Hits	294	Shared Neighborhood Hits	277
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

CENB5_HUMAN
θ value	0.00020696 (rank : 220)	NC score	0.554396 (rank : 219)
Query Neighborhood Hits	435	Target Neighborhood Hits	395	Shared Neighborhood Hits	262
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CT012_HUMAN
θ value	0.00020696 (rank : 221)	NC score	0.463970 (rank : 244)
Query Neighborhood Hits	435	Target Neighborhood Hits	205	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

ANR38_MOUSE
θ value	0.000270298 (rank : 222)	NC score	0.667957 (rank : 184)
Query Neighborhood Hits	435	Target Neighborhood Hits	512	Shared Neighborhood Hits	239
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

NFKB2_HUMAN
θ value	0.000270298 (rank : 223)	NC score	0.714542 (rank : 171)
Query Neighborhood Hits	435	Target Neighborhood Hits	325	Shared Neighborhood Hits	277
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

FBX41_HUMAN
θ value	0.000461057 (rank : 224)	NC score	0.042128 (rank : 351)
Query Neighborhood Hits	435	Target Neighborhood Hits	475	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

KRIT1_MOUSE
θ value	0.000461057 (rank : 225)	NC score	0.674731 (rank : 179)
Query Neighborhood Hits	435	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

S23IP_MOUSE
θ value	0.000461057 (rank : 226)	NC score	0.102135 (rank : 303)
Query Neighborhood Hits	435	Target Neighborhood Hits	363	Shared Neighborhood Hits	48
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

AN13A_HUMAN
θ value	0.000602161 (rank : 227)	NC score	0.476058 (rank : 241)
Query Neighborhood Hits	435	Target Neighborhood Hits	243	Shared Neighborhood Hits	224
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ANR22_HUMAN
θ value	0.000602161 (rank : 228)	NC score	0.805642 (rank : 118)
Query Neighborhood Hits	435	Target Neighborhood Hits	243	Shared Neighborhood Hits	239
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ASB6_HUMAN
θ value	0.000602161 (rank : 229)	NC score	0.753942 (rank : 150)
Query Neighborhood Hits	435	Target Neighborhood Hits	256	Shared Neighborhood Hits	246
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CD2A1_HUMAN
θ value	0.000602161 (rank : 230)	NC score	0.647946 (rank : 192)
Query Neighborhood Hits	435	Target Neighborhood Hits	196	Shared Neighborhood Hits	194
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

ANR10_MOUSE
θ value	0.000786445 (rank : 231)	NC score	0.803493 (rank : 119)
Query Neighborhood Hits	435	Target Neighborhood Hits	273	Shared Neighborhood Hits	265
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR41_HUMAN
θ value	0.000786445 (rank : 232)	NC score	0.763005 (rank : 144)
Query Neighborhood Hits	435	Target Neighborhood Hits	332	Shared Neighborhood Hits	252
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

LRSM1_HUMAN
θ value	0.000786445 (rank : 233)	NC score	0.062190 (rank : 322)
Query Neighborhood Hits	435	Target Neighborhood Hits	1078	Shared Neighborhood Hits	46
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

NOTC1_MOUSE
θ value	0.000786445 (rank : 234)	NC score	0.353098 (rank : 269)
Query Neighborhood Hits	435	Target Neighborhood Hits	916	Shared Neighborhood Hits	265
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANKY1_HUMAN
θ value	0.00134147 (rank : 235)	NC score	0.591886 (rank : 208)
Query Neighborhood Hits	435	Target Neighborhood Hits	248	Shared Neighborhood Hits	203
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ANR32_HUMAN
θ value	0.00134147 (rank : 236)	NC score	0.766672 (rank : 142)
Query Neighborhood Hits	435	Target Neighborhood Hits	270	Shared Neighborhood Hits	259
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR45_HUMAN
θ value	0.00134147 (rank : 237)	NC score	0.590814 (rank : 209)
Query Neighborhood Hits	435	Target Neighborhood Hits	201	Shared Neighborhood Hits	183
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

OGFR_HUMAN
θ value	0.00175202 (rank : 238)	NC score	0.058740 (rank : 325)
Query Neighborhood Hits	435	Target Neighborhood Hits	1582	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ASB4_HUMAN
θ value	0.00228821 (rank : 239)	NC score	0.795763 (rank : 128)
Query Neighborhood Hits	435	Target Neighborhood Hits	264	Shared Neighborhood Hits	255
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

AN13A_MOUSE
θ value	0.00298849 (rank : 240)	NC score	0.449534 (rank : 251)
Query Neighborhood Hits	435	Target Neighborhood Hits	226	Shared Neighborhood Hits	214
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

NFKB2_MOUSE
θ value	0.00390308 (rank : 241)	NC score	0.696289 (rank : 176)
Query Neighborhood Hits	435	Target Neighborhood Hits	326	Shared Neighborhood Hits	270
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANKZ1_HUMAN
θ value	0.00509761 (rank : 242)	NC score	0.358555 (rank : 266)
Query Neighborhood Hits	435	Target Neighborhood Hits	236	Shared Neighborhood Hits	157
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ANR32_MOUSE
θ value	0.00509761 (rank : 243)	NC score	0.756430 (rank : 149)
Query Neighborhood Hits	435	Target Neighborhood Hits	285	Shared Neighborhood Hits	258
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

AN13B_HUMAN
θ value	0.00665767 (rank : 244)	NC score	0.531541 (rank : 225)
Query Neighborhood Hits	435	Target Neighborhood Hits	265	Shared Neighborhood Hits	252
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	0.00665767 (rank : 245)	NC score	0.532328 (rank : 223)
Query Neighborhood Hits	435	Target Neighborhood Hits	276	Shared Neighborhood Hits	253
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

SNCAP_HUMAN
θ value	0.00869519 (rank : 246)	NC score	0.709647 (rank : 172)
Query Neighborhood Hits	435	Target Neighborhood Hits	313	Shared Neighborhood Hits	240
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ZCH14_HUMAN
θ value	0.00869519 (rank : 247)	NC score	0.071120 (rank : 319)
Query Neighborhood Hits	435	Target Neighborhood Hits	117	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

DDFL1_MOUSE
θ value	0.0113563 (rank : 248)	NC score	0.453688 (rank : 249)
Query Neighborhood Hits	435	Target Neighborhood Hits	324	Shared Neighborhood Hits	249
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DGKI_HUMAN
θ value	0.0113563 (rank : 249)	NC score	0.352518 (rank : 270)
Query Neighborhood Hits	435	Target Neighborhood Hits	609	Shared Neighborhood Hits	218
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

LRRK1_MOUSE
θ value	0.0113563 (rank : 250)	NC score	0.101703 (rank : 304)
Query Neighborhood Hits	435	Target Neighborhood Hits	1267	Shared Neighborhood Hits	128
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

ANR37_HUMAN
θ value	0.0148317 (rank : 251)	NC score	0.716578 (rank : 170)
Query Neighborhood Hits	435	Target Neighborhood Hits	247	Shared Neighborhood Hits	243
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

CENG2_MOUSE
θ value	0.0148317 (rank : 252)	NC score	0.351373 (rank : 271)
Query Neighborhood Hits	435	Target Neighborhood Hits	463	Shared Neighborhood Hits	249
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

LRRK1_HUMAN
θ value	0.0148317 (rank : 253)	NC score	0.079323 (rank : 315)
Query Neighborhood Hits	435	Target Neighborhood Hits	1237	Shared Neighborhood Hits	102
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

LRSM1_MOUSE
θ value	0.0148317 (rank : 254)	NC score	0.057628 (rank : 327)
Query Neighborhood Hits	435	Target Neighborhood Hits	874	Shared Neighborhood Hits	37
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

AN36A_HUMAN
θ value	0.0193708 (rank : 255)	NC score	0.757564 (rank : 147)
Query Neighborhood Hits	435	Target Neighborhood Hits	271	Shared Neighborhood Hits	263
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR43_HUMAN
θ value	0.0193708 (rank : 256)	NC score	0.614799 (rank : 203)
Query Neighborhood Hits	435	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ASB4_MOUSE
θ value	0.0193708 (rank : 257)	NC score	0.788512 (rank : 130)
Query Neighborhood Hits	435	Target Neighborhood Hits	265	Shared Neighborhood Hits	255
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

CENG2_HUMAN
θ value	0.0193708 (rank : 258)	NC score	0.354160 (rank : 268)
Query Neighborhood Hits	435	Target Neighborhood Hits	471	Shared Neighborhood Hits	252
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

KRIT1_HUMAN
θ value	0.0193708 (rank : 259)	NC score	0.659703 (rank : 187)
Query Neighborhood Hits	435	Target Neighborhood Hits	258	Shared Neighborhood Hits	223
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

S23IP_HUMAN
θ value	0.0193708 (rank : 260)	NC score	0.087583 (rank : 310)
Query Neighborhood Hits	435	Target Neighborhood Hits	134	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

ASB14_HUMAN
θ value	0.0252991 (rank : 261)	NC score	0.556247 (rank : 217)
Query Neighborhood Hits	435	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CDN2B_MOUSE
θ value	0.0252991 (rank : 262)	NC score	0.674054 (rank : 180)
Query Neighborhood Hits	435	Target Neighborhood Hits	201	Shared Neighborhood Hits	200
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

EVL_HUMAN
θ value	0.0252991 (rank : 263)	NC score	0.054720 (rank : 331)
Query Neighborhood Hits	435	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

ZCH14_MOUSE
θ value	0.0252991 (rank : 264)	NC score	0.068011 (rank : 321)
Query Neighborhood Hits	435	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ANKZ1_MOUSE
θ value	0.0330416 (rank : 265)	NC score	0.363837 (rank : 265)
Query Neighborhood Hits	435	Target Neighborhood Hits	208	Shared Neighborhood Hits	151
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

EVL_MOUSE
θ value	0.0330416 (rank : 266)	NC score	0.045559 (rank : 348)
Query Neighborhood Hits	435	Target Neighborhood Hits	203	Shared Neighborhood Hits	25
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

KIFC1_HUMAN
θ value	0.0330416 (rank : 267)	NC score	0.015317 (rank : 405)
Query Neighborhood Hits	435	Target Neighborhood Hits	545	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

SARM1_HUMAN
θ value	0.0330416 (rank : 268)	NC score	0.081895 (rank : 313)
Query Neighborhood Hits	435	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

SARM1_MOUSE
θ value	0.0330416 (rank : 269)	NC score	0.085703 (rank : 311)
Query Neighborhood Hits	435	Target Neighborhood Hits	54	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

TRPV4_HUMAN
θ value	0.0330416 (rank : 270)	NC score	0.167911 (rank : 297)
Query Neighborhood Hits	435	Target Neighborhood Hits	150	Shared Neighborhood Hits	86
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

ANR43_MOUSE
θ value	0.0431538 (rank : 271)	NC score	0.608824 (rank : 205)
Query Neighborhood Hits	435	Target Neighborhood Hits	214	Shared Neighborhood Hits	206
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

GIT2_MOUSE
θ value	0.0431538 (rank : 272)	NC score	0.507741 (rank : 230)
Query Neighborhood Hits	435	Target Neighborhood Hits	323	Shared Neighborhood Hits	251
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

TRPV3_MOUSE
θ value	0.0431538 (rank : 273)	NC score	0.275909 (rank : 283)
Query Neighborhood Hits	435	Target Neighborhood Hits	188	Shared Neighborhood Hits	135
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_MOUSE
θ value	0.0431538 (rank : 274)	NC score	0.157426 (rank : 299)
Query Neighborhood Hits	435	Target Neighborhood Hits	117	Shared Neighborhood Hits	81
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

AKA10_MOUSE
θ value	0.0563607 (rank : 275)	NC score	0.025355 (rank : 382)
Query Neighborhood Hits	435	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

BRD8_MOUSE
θ value	0.0563607 (rank : 276)	NC score	0.025254 (rank : 384)
Query Neighborhood Hits	435	Target Neighborhood Hits	422	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BAT4_HUMAN
θ value	0.0736092 (rank : 277)	NC score	0.289531 (rank : 281)
Query Neighborhood Hits	435	Target Neighborhood Hits	157	Shared Neighborhood Hits	110
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

DGKD_HUMAN
θ value	0.0736092 (rank : 278)	NC score	0.058813 (rank : 324)
Query Neighborhood Hits	435	Target Neighborhood Hits	231	Shared Neighborhood Hits	35
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

GON4L_MOUSE
θ value	0.0736092 (rank : 279)	NC score	0.045655 (rank : 347)
Query Neighborhood Hits	435	Target Neighborhood Hits	455	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

NFH_MOUSE
θ value	0.0736092 (rank : 280)	NC score	0.036537 (rank : 357)
Query Neighborhood Hits	435	Target Neighborhood Hits	2247	Shared Neighborhood Hits	113
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RIN1_MOUSE
θ value	0.0736092 (rank : 281)	NC score	0.024550 (rank : 385)
Query Neighborhood Hits	435	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).

CENG1_HUMAN
θ value	0.125558 (rank : 282)	NC score	0.347842 (rank : 273)
Query Neighborhood Hits	435	Target Neighborhood Hits	544	Shared Neighborhood Hits	254
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	0.125558 (rank : 283)	NC score	0.350724 (rank : 272)
Query Neighborhood Hits	435	Target Neighborhood Hits	531	Shared Neighborhood Hits	253
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

GIT1_HUMAN
θ value	0.125558 (rank : 284)	NC score	0.488137 (rank : 240)
Query Neighborhood Hits	435	Target Neighborhood Hits	336	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	0.125558 (rank : 285)	NC score	0.489357 (rank : 239)
Query Neighborhood Hits	435	Target Neighborhood Hits	341	Shared Neighborhood Hits	248
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

TRPV3_HUMAN
θ value	0.125558 (rank : 286)	NC score	0.275731 (rank : 284)
Query Neighborhood Hits	435	Target Neighborhood Hits	198	Shared Neighborhood Hits	146
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

AN13C_HUMAN
θ value	0.163984 (rank : 287)	NC score	0.511790 (rank : 229)
Query Neighborhood Hits	435	Target Neighborhood Hits	241	Shared Neighborhood Hits	233
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ANR45_MOUSE
θ value	0.163984 (rank : 288)	NC score	0.615305 (rank : 202)
Query Neighborhood Hits	435	Target Neighborhood Hits	204	Shared Neighborhood Hits	188
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

BAT4_MOUSE
θ value	0.163984 (rank : 289)	NC score	0.313457 (rank : 277)
Query Neighborhood Hits	435	Target Neighborhood Hits	171	Shared Neighborhood Hits	123
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CENG3_HUMAN
θ value	0.163984 (rank : 290)	NC score	0.316706 (rank : 276)
Query Neighborhood Hits	435	Target Neighborhood Hits	455	Shared Neighborhood Hits	228
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	0.163984 (rank : 291)	NC score	0.317310 (rank : 275)
Query Neighborhood Hits	435	Target Neighborhood Hits	467	Shared Neighborhood Hits	230
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

DUS16_HUMAN
θ value	0.163984 (rank : 292)	NC score	0.009377 (rank : 428)
Query Neighborhood Hits	435	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

GIT2_HUMAN
θ value	0.163984 (rank : 293)	NC score	0.467102 (rank : 243)
Query Neighborhood Hits	435	Target Neighborhood Hits	381	Shared Neighborhood Hits	245
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

SAM14_MOUSE
θ value	0.163984 (rank : 294)	NC score	0.077506 (rank : 316)
Query Neighborhood Hits	435	Target Neighborhood Hits	91	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

TGON2_HUMAN
θ value	0.163984 (rank : 295)	NC score	0.045898 (rank : 346)
Query Neighborhood Hits	435	Target Neighborhood Hits	1037	Shared Neighborhood Hits	75
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TRPV1_MOUSE
θ value	0.163984 (rank : 296)	NC score	0.274847 (rank : 285)
Query Neighborhood Hits	435	Target Neighborhood Hits	189	Shared Neighborhood Hits	157
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

CBX2_MOUSE
θ value	0.21417 (rank : 297)	NC score	0.026721 (rank : 379)
Query Neighborhood Hits	435	Target Neighborhood Hits	119	Shared Neighborhood Hits	15
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CD2_HUMAN
θ value	0.21417 (rank : 298)	NC score	0.029589 (rank : 367)
Query Neighborhood Hits	435	Target Neighborhood Hits	504	Shared Neighborhood Hits	33
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

IRX5_MOUSE
θ value	0.21417 (rank : 299)	NC score	0.014746 (rank : 408)
Query Neighborhood Hits	435	Target Neighborhood Hits	324	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

MYO9B_HUMAN
θ value	0.21417 (rank : 300)	NC score	0.007908 (rank : 431)
Query Neighborhood Hits	435	Target Neighborhood Hits	641	Shared Neighborhood Hits	47
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

AN13C_MOUSE
θ value	0.279714 (rank : 301)	NC score	0.500144 (rank : 236)
Query Neighborhood Hits	435	Target Neighborhood Hits	242	Shared Neighborhood Hits	229
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

BI2L1_HUMAN
θ value	0.279714 (rank : 302)	NC score	0.025282 (rank : 383)
Query Neighborhood Hits	435	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

CNKR2_HUMAN
θ value	0.279714 (rank : 303)	NC score	0.054786 (rank : 330)
Query Neighborhood Hits	435	Target Neighborhood Hits	197	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	0.279714 (rank : 304)	NC score	0.054664 (rank : 332)
Query Neighborhood Hits	435	Target Neighborhood Hits	197	Shared Neighborhood Hits	25
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PGCA_MOUSE
θ value	0.279714 (rank : 305)	NC score	0.006668 (rank : 442)
Query Neighborhood Hits	435	Target Neighborhood Hits	643	Shared Neighborhood Hits	33
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

WASIP_MOUSE
θ value	0.279714 (rank : 306)	NC score	0.055111 (rank : 328)
Query Neighborhood Hits	435	Target Neighborhood Hits	392	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

CMTA2_HUMAN
θ value	0.365318 (rank : 307)	NC score	0.174168 (rank : 296)
Query Neighborhood Hits	435	Target Neighborhood Hits	199	Shared Neighborhood Hits	98
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
θ value	0.365318 (rank : 308)	NC score	0.161866 (rank : 298)
Query Neighborhood Hits	435	Target Neighborhood Hits	216	Shared Neighborhood Hits	87
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TPR_HUMAN
θ value	0.365318 (rank : 309)	NC score	0.040238 (rank : 354)
Query Neighborhood Hits	435	Target Neighborhood Hits	1921	Shared Neighborhood Hits	77
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRPC6_HUMAN
θ value	0.365318 (rank : 310)	NC score	0.126465 (rank : 301)
Query Neighborhood Hits	435	Target Neighborhood Hits	171	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

DDFL1_HUMAN
θ value	0.47712 (rank : 311)	NC score	0.354891 (rank : 267)
Query Neighborhood Hits	435	Target Neighborhood Hits	353	Shared Neighborhood Hits	232
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

RGS3_MOUSE
θ value	0.47712 (rank : 312)	NC score	0.030844 (rank : 366)
Query Neighborhood Hits	435	Target Neighborhood Hits	1621	Shared Neighborhood Hits	91
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TRPC3_HUMAN
θ value	0.47712 (rank : 313)	NC score	0.104052 (rank : 302)
Query Neighborhood Hits	435	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC6_MOUSE
θ value	0.47712 (rank : 314)	NC score	0.098588 (rank : 305)
Query Neighborhood Hits	435	Target Neighborhood Hits	171	Shared Neighborhood Hits	94
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPV1_HUMAN
θ value	0.47712 (rank : 315)	NC score	0.257594 (rank : 289)
Query Neighborhood Hits	435	Target Neighborhood Hits	184	Shared Neighborhood Hits	149
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

BSN_MOUSE
θ value	0.62314 (rank : 316)	NC score	0.049734 (rank : 341)
Query Neighborhood Hits	435	Target Neighborhood Hits	2057	Shared Neighborhood Hits	133
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

LIPB2_HUMAN
θ value	0.62314 (rank : 317)	NC score	0.038908 (rank : 356)
Query Neighborhood Hits	435	Target Neighborhood Hits	599	Shared Neighborhood Hits	38
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

PI5PA_HUMAN
θ value	0.62314 (rank : 318)	NC score	0.040603 (rank : 353)
Query Neighborhood Hits	435	Target Neighborhood Hits	749	Shared Neighborhood Hits	60
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RANB3_MOUSE
θ value	0.62314 (rank : 319)	NC score	0.023216 (rank : 387)
Query Neighborhood Hits	435	Target Neighborhood Hits	123	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

SAM14_HUMAN
θ value	0.62314 (rank : 320)	NC score	0.070999 (rank : 320)
Query Neighborhood Hits	435	Target Neighborhood Hits	81	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

X3CL1_HUMAN
θ value	0.62314 (rank : 321)	NC score	0.031020 (rank : 365)
Query Neighborhood Hits	435	Target Neighborhood Hits	152	Shared Neighborhood Hits	13
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

APLP1_MOUSE
θ value	0.813845 (rank : 322)	NC score	0.010458 (rank : 423)
Query Neighborhood Hits	435	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	Q03157, Q8VC38	Gene names	Aplp1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

GRIN1_MOUSE
θ value	0.813845 (rank : 323)	NC score	0.034436 (rank : 360)
Query Neighborhood Hits	435	Target Neighborhood Hits	337	Shared Neighborhood Hits	40
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

IF16_HUMAN
θ value	0.813845 (rank : 324)	NC score	0.022509 (rank : 390)
Query Neighborhood Hits	435	Target Neighborhood Hits	182	Shared Neighborhood Hits	20
SwissProt Accessions	Q16666, Q9UH78	Gene names	IFI16, IFNGIP1
Domain Architecture
Description	Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16).

JHD2B_HUMAN
θ value	0.813845 (rank : 325)	NC score	0.016295 (rank : 404)
Query Neighborhood Hits	435	Target Neighborhood Hits	171	Shared Neighborhood Hits	16
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

ANR37_MOUSE
θ value	1.06291 (rank : 326)	NC score	0.681781 (rank : 177)
Query Neighborhood Hits	435	Target Neighborhood Hits	237	Shared Neighborhood Hits	234
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

BPA1_MOUSE
θ value	1.06291 (rank : 327)	NC score	0.017605 (rank : 401)
Query Neighborhood Hits	435	Target Neighborhood Hits	1477	Shared Neighborhood Hits	53
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DGKH_HUMAN
θ value	1.06291 (rank : 328)	NC score	0.044413 (rank : 350)
Query Neighborhood Hits	435	Target Neighborhood Hits	255	Shared Neighborhood Hits	33
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

EMSY_HUMAN
θ value	1.06291 (rank : 329)	NC score	0.019980 (rank : 395)
Query Neighborhood Hits	435	Target Neighborhood Hits	296	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

GON4L_HUMAN
θ value	1.06291 (rank : 330)	NC score	0.035465 (rank : 358)
Query Neighborhood Hits	435	Target Neighborhood Hits	555	Shared Neighborhood Hits	40
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

MAK_MOUSE
θ value	1.06291 (rank : 331)	NC score	0.005444 (rank : 445)
Query Neighborhood Hits	435	Target Neighborhood Hits	873	Shared Neighborhood Hits	25
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

MUCDL_HUMAN
θ value	1.06291 (rank : 332)	NC score	0.042074 (rank : 352)
Query Neighborhood Hits	435	Target Neighborhood Hits	777	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

CDN2B_HUMAN
θ value	1.38821 (rank : 333)	NC score	0.629124 (rank : 196)
Query Neighborhood Hits	435	Target Neighborhood Hits	196	Shared Neighborhood Hits	194
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CLR59_HUMAN
θ value	1.38821 (rank : 334)	NC score	0.282080 (rank : 282)
Query Neighborhood Hits	435	Target Neighborhood Hits	163	Shared Neighborhood Hits	140
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

GLSL_HUMAN
θ value	1.38821 (rank : 335)	NC score	0.506436 (rank : 231)
Query Neighborhood Hits	435	Target Neighborhood Hits	211	Shared Neighborhood Hits	201
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

JHD2B_MOUSE
θ value	1.38821 (rank : 336)	NC score	0.012299 (rank : 417)
Query Neighborhood Hits	435	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

NACAM_MOUSE
θ value	1.38821 (rank : 337)	NC score	0.047488 (rank : 345)
Query Neighborhood Hits	435	Target Neighborhood Hits	1866	Shared Neighborhood Hits	111
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TACT_HUMAN
θ value	1.38821 (rank : 338)	NC score	0.025814 (rank : 381)
Query Neighborhood Hits	435	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	P40200	Gene names	CD96
Domain Architecture	No domain graphic available
Description	T-cell surface protein tactile precursor (T cell-activated increased late expression protein) (CD96 antigen).

US6NL_HUMAN
θ value	1.38821 (rank : 339)	NC score	0.009595 (rank : 427)
Query Neighborhood Hits	435	Target Neighborhood Hits	201	Shared Neighborhood Hits	18
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

CTND2_HUMAN
θ value	1.81305 (rank : 340)	NC score	0.019164 (rank : 398)
Query Neighborhood Hits	435	Target Neighborhood Hits	333	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

EFNB2_HUMAN
θ value	1.81305 (rank : 341)	NC score	0.010272 (rank : 424)
Query Neighborhood Hits	435	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P52799	Gene names	EFNB2, EPLG5, HTKL, LERK5
Domain Architecture
Description	Ephrin-B2 precursor (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L).

MAML2_HUMAN
θ value	1.81305 (rank : 342)	NC score	0.027908 (rank : 372)
Query Neighborhood Hits	435	Target Neighborhood Hits	360	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

PUNC_MOUSE
θ value	1.81305 (rank : 343)	NC score	-0.002058 (rank : 456)
Query Neighborhood Hits	435	Target Neighborhood Hits	501	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

RASF2_MOUSE
θ value	1.81305 (rank : 344)	NC score	0.007677 (rank : 433)
Query Neighborhood Hits	435	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BMS9, Q6A0B2	Gene names	Rassf2, Kiaa0168
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 2.

SRRM2_HUMAN
θ value	1.81305 (rank : 345)	NC score	0.061756 (rank : 323)
Query Neighborhood Hits	435	Target Neighborhood Hits	1296	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRPC3_MOUSE
θ value	1.81305 (rank : 346)	NC score	0.096823 (rank : 306)
Query Neighborhood Hits	435	Target Neighborhood Hits	131	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

APBB2_MOUSE
θ value	2.36792 (rank : 347)	NC score	0.007169 (rank : 437)
Query Neighborhood Hits	435	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

BRD4_MOUSE
θ value	2.36792 (rank : 348)	NC score	0.027837 (rank : 373)
Query Neighborhood Hits	435	Target Neighborhood Hits	845	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

FRM4A_MOUSE
θ value	2.36792 (rank : 349)	NC score	0.002236 (rank : 453)
Query Neighborhood Hits	435	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

GLIS1_HUMAN
θ value	2.36792 (rank : 350)	NC score	-0.011663 (rank : 458)
Query Neighborhood Hits	435	Target Neighborhood Hits	748	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

HRBL_MOUSE
θ value	2.36792 (rank : 351)	NC score	0.039267 (rank : 355)
Query Neighborhood Hits	435	Target Neighborhood Hits	269	Shared Neighborhood Hits	33
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

JIP1_HUMAN
θ value	2.36792 (rank : 352)	NC score	0.022511 (rank : 389)
Query Neighborhood Hits	435	Target Neighborhood Hits	271	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

LMBL3_HUMAN
θ value	2.36792 (rank : 353)	NC score	0.013198 (rank : 412)
Query Neighborhood Hits	435	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q96JM7, Q5VUM9, Q6P9B5	Gene names	L3MBTL3, KIAA1798
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein) (H-l(3)mbt-like protein).

PHF12_HUMAN
θ value	2.36792 (rank : 354)	NC score	0.008057 (rank : 430)
Query Neighborhood Hits	435	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

SAPS1_HUMAN
θ value	2.36792 (rank : 355)	NC score	0.020256 (rank : 394)
Query Neighborhood Hits	435	Target Neighborhood Hits	704	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SRBS1_MOUSE
θ value	2.36792 (rank : 356)	NC score	0.021768 (rank : 391)
Query Neighborhood Hits	435	Target Neighborhood Hits	409	Shared Neighborhood Hits	29
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRPK2_HUMAN
θ value	2.36792 (rank : 357)	NC score	0.006721 (rank : 440)
Query Neighborhood Hits	435	Target Neighborhood Hits	664	Shared Neighborhood Hits	18
SwissProt Accessions	P78362, O75220, O75221, Q6NUL0, Q6V1X2, Q8IYQ3	Gene names	SRPK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

SSBP4_HUMAN
θ value	2.36792 (rank : 358)	NC score	0.011454 (rank : 420)
Query Neighborhood Hits	435	Target Neighborhood Hits	753	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TRPC7_HUMAN
θ value	2.36792 (rank : 359)	NC score	0.090242 (rank : 309)
Query Neighborhood Hits	435	Target Neighborhood Hits	123	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

WDR20_HUMAN
θ value	2.36792 (rank : 360)	NC score	0.006408 (rank : 443)
Query Neighborhood Hits	435	Target Neighborhood Hits	249	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

ABTB1_MOUSE
θ value	3.0926 (rank : 361)	NC score	0.307742 (rank : 278)
Query Neighborhood Hits	435	Target Neighborhood Hits	349	Shared Neighborhood Hits	176
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

AFF1_MOUSE
θ value	3.0926 (rank : 362)	NC score	0.027242 (rank : 377)
Query Neighborhood Hits	435	Target Neighborhood Hits	351	Shared Neighborhood Hits	43
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

CTND2_MOUSE
θ value	3.0926 (rank : 363)	NC score	0.014878 (rank : 407)
Query Neighborhood Hits	435	Target Neighborhood Hits	227	Shared Neighborhood Hits	20
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

EMSY_MOUSE
θ value	3.0926 (rank : 364)	NC score	0.019724 (rank : 396)
Query Neighborhood Hits	435	Target Neighborhood Hits	294	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

GA2L3_HUMAN
θ value	3.0926 (rank : 365)	NC score	0.016912 (rank : 403)
Query Neighborhood Hits	435	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

GLSL_MOUSE
θ value	3.0926 (rank : 366)	NC score	0.493695 (rank : 238)
Query Neighborhood Hits	435	Target Neighborhood Hits	212	Shared Neighborhood Hits	202
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ITIH3_MOUSE
θ value	3.0926 (rank : 367)	NC score	0.010181 (rank : 425)
Query Neighborhood Hits	435	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q61704	Gene names	Itih3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3).

RANB3_HUMAN
θ value	3.0926 (rank : 368)	NC score	0.027291 (rank : 376)
Query Neighborhood Hits	435	Target Neighborhood Hits	117	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

RTP3_MOUSE
θ value	3.0926 (rank : 369)	NC score	0.031987 (rank : 363)
Query Neighborhood Hits	435	Target Neighborhood Hits	374	Shared Neighborhood Hits	36
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

TM108_MOUSE
θ value	3.0926 (rank : 370)	NC score	0.028250 (rank : 369)
Query Neighborhood Hits	435	Target Neighborhood Hits	336	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TRPC7_MOUSE
θ value	3.0926 (rank : 371)	NC score	0.090512 (rank : 308)
Query Neighborhood Hits	435	Target Neighborhood Hits	114	Shared Neighborhood Hits	77
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

ASXL1_MOUSE
θ value	4.03905 (rank : 372)	NC score	0.012784 (rank : 415)
Query Neighborhood Hits	435	Target Neighborhood Hits	182	Shared Neighborhood Hits	22
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

BRD8_HUMAN
θ value	4.03905 (rank : 373)	NC score	0.019354 (rank : 397)
Query Neighborhood Hits	435	Target Neighborhood Hits	292	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

CD320_HUMAN
θ value	4.03905 (rank : 374)	NC score	0.007738 (rank : 432)
Query Neighborhood Hits	435	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

DCJ14_HUMAN
θ value	4.03905 (rank : 375)	NC score	0.002813 (rank : 451)
Query Neighborhood Hits	435	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q6Y2X3, Q66K17, Q96N59, Q96T63	Gene names	DNAJC14, DRIP78
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 14 (Dopamine receptor-interacting protein of 78 kDa) (DRiP78).

DGKZ_HUMAN
θ value	4.03905 (rank : 376)	NC score	0.369025 (rank : 262)
Query Neighborhood Hits	435	Target Neighborhood Hits	551	Shared Neighborhood Hits	219
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

FLVC2_MOUSE
θ value	4.03905 (rank : 377)	NC score	0.007347 (rank : 436)
Query Neighborhood Hits	435	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q91X85	Gene names	Flvcr2
Domain Architecture	No domain graphic available
Description	Feline leukemia virus subgroup C receptor-related protein 2 (Calcium- chelate transporter) (CCT).

GRIN1_HUMAN
θ value	4.03905 (rank : 378)	NC score	0.044745 (rank : 349)
Query Neighborhood Hits	435	Target Neighborhood Hits	681	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MEGF9_MOUSE
θ value	4.03905 (rank : 379)	NC score	0.027975 (rank : 371)
Query Neighborhood Hits	435	Target Neighborhood Hits	896	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NCOA6_HUMAN
θ value	4.03905 (rank : 380)	NC score	0.035313 (rank : 359)
Query Neighborhood Hits	435	Target Neighborhood Hits	1202	Shared Neighborhood Hits	82
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TGON2_MOUSE
θ value	4.03905 (rank : 381)	NC score	0.023811 (rank : 386)
Query Neighborhood Hits	435	Target Neighborhood Hits	277	Shared Neighborhood Hits	19
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TTLL5_MOUSE
θ value	4.03905 (rank : 382)	NC score	0.007388 (rank : 435)
Query Neighborhood Hits	435	Target Neighborhood Hits	150	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

WDR46_MOUSE
θ value	4.03905 (rank : 383)	NC score	0.014199 (rank : 409)
Query Neighborhood Hits	435	Target Neighborhood Hits	243	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

ZN142_HUMAN
θ value	4.03905 (rank : 384)	NC score	-0.011816 (rank : 459)
Query Neighborhood Hits	435	Target Neighborhood Hits	1007	Shared Neighborhood Hits	26
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

ZRF1_HUMAN
θ value	4.03905 (rank : 385)	NC score	0.010679 (rank : 422)
Query Neighborhood Hits	435	Target Neighborhood Hits	457	Shared Neighborhood Hits	15
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

EFNB2_MOUSE
θ value	5.27518 (rank : 386)	NC score	0.008235 (rank : 429)
Query Neighborhood Hits	435	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	P52800	Gene names	Efnb2, Elf2, Epl5, Eplg5, Htkl, Lerk5
Domain Architecture
Description	Ephrin-B2 precursor (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L) (ELF-2).

GA2L2_HUMAN
θ value	5.27518 (rank : 387)	NC score	0.012018 (rank : 418)
Query Neighborhood Hits	435	Target Neighborhood Hits	175	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

LCP2_HUMAN
θ value	5.27518 (rank : 388)	NC score	0.027982 (rank : 370)
Query Neighborhood Hits	435	Target Neighborhood Hits	531	Shared Neighborhood Hits	37
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MRCKB_HUMAN
θ value	5.27518 (rank : 389)	NC score	0.020298 (rank : 393)
Query Neighborhood Hits	435	Target Neighborhood Hits	2239	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PCLO_MOUSE
θ value	5.27518 (rank : 390)	NC score	0.032772 (rank : 361)
Query Neighborhood Hits	435	Target Neighborhood Hits	2275	Shared Neighborhood Hits	113
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDXL2_MOUSE
θ value	5.27518 (rank : 391)	NC score	0.014112 (rank : 410)
Query Neighborhood Hits	435	Target Neighborhood Hits	213	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

PUR2_MOUSE
θ value	5.27518 (rank : 392)	NC score	0.006698 (rank : 441)
Query Neighborhood Hits	435	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q64737, Q6NS48	Gene names	Gart
Domain Architecture
Description	Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIRS) (Phosphoribosyl-aminoimidazole synthetase) (AIR synthase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (GART) (GAR transformylase) (5'-phosphoribosylglycinamide transformylase)].

SI1L3_HUMAN
θ value	5.27518 (rank : 393)	NC score	0.007090 (rank : 439)
Query Neighborhood Hits	435	Target Neighborhood Hits	305	Shared Neighborhood Hits	28
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SPEG_MOUSE
θ value	5.27518 (rank : 394)	NC score	0.010763 (rank : 421)
Query Neighborhood Hits	435	Target Neighborhood Hits	1959	Shared Neighborhood Hits	81
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRRM2_MOUSE
θ value	5.27518 (rank : 395)	NC score	0.048757 (rank : 342)
Query Neighborhood Hits	435	Target Neighborhood Hits	1470	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TENS1_HUMAN
θ value	5.27518 (rank : 396)	NC score	0.011734 (rank : 419)
Query Neighborhood Hits	435	Target Neighborhood Hits	400	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

THSD1_MOUSE
θ value	5.27518 (rank : 397)	NC score	0.003214 (rank : 450)
Query Neighborhood Hits	435	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

AMOL1_MOUSE
θ value	6.88961 (rank : 398)	NC score	0.023110 (rank : 388)
Query Neighborhood Hits	435	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

DDEF2_HUMAN
θ value	6.88961 (rank : 399)	NC score	0.366176 (rank : 263)
Query Neighborhood Hits	435	Target Neighborhood Hits	599	Shared Neighborhood Hits	245
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	6.88961 (rank : 400)	NC score	0.365439 (rank : 264)
Query Neighborhood Hits	435	Target Neighborhood Hits	625	Shared Neighborhood Hits	254
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DLG5_HUMAN
θ value	6.88961 (rank : 401)	NC score	0.018798 (rank : 399)
Query Neighborhood Hits	435	Target Neighborhood Hits	1088	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

FGD1_MOUSE
θ value	6.88961 (rank : 402)	NC score	0.009700 (rank : 426)
Query Neighborhood Hits	435	Target Neighborhood Hits	387	Shared Neighborhood Hits	32
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FILA_HUMAN
θ value	6.88961 (rank : 403)	NC score	0.017928 (rank : 400)
Query Neighborhood Hits	435	Target Neighborhood Hits	685	Shared Neighborhood Hits	32
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GLSK_HUMAN
θ value	6.88961 (rank : 404)	NC score	0.459448 (rank : 246)
Query Neighborhood Hits	435	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

IL3B2_MOUSE
θ value	6.88961 (rank : 405)	NC score	0.004138 (rank : 447)
Query Neighborhood Hits	435	Target Neighborhood Hits	372	Shared Neighborhood Hits	18
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IQEC3_MOUSE
θ value	6.88961 (rank : 406)	NC score	0.012741 (rank : 416)
Query Neighborhood Hits	435	Target Neighborhood Hits	274	Shared Neighborhood Hits	29
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

MACOI_MOUSE
θ value	6.88961 (rank : 407)	NC score	0.032658 (rank : 362)
Query Neighborhood Hits	435	Target Neighborhood Hits	620	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MCPH1_MOUSE
θ value	6.88961 (rank : 408)	NC score	0.026913 (rank : 378)
Query Neighborhood Hits	435	Target Neighborhood Hits	116	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

PRR8_HUMAN
θ value	6.88961 (rank : 409)	NC score	0.031394 (rank : 364)
Query Neighborhood Hits	435	Target Neighborhood Hits	217	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

PTPRV_MOUSE
θ value	6.88961 (rank : 410)	NC score	-0.001651 (rank : 455)
Query Neighborhood Hits	435	Target Neighborhood Hits	179	Shared Neighborhood Hits	5
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

RNF31_HUMAN
θ value	6.88961 (rank : 411)	NC score	0.003300 (rank : 449)
Query Neighborhood Hits	435	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

TRPC5_HUMAN
θ value	6.88961 (rank : 412)	NC score	0.081743 (rank : 314)
Query Neighborhood Hits	435	Target Neighborhood Hits	122	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	6.88961 (rank : 413)	NC score	0.083089 (rank : 312)
Query Neighborhood Hits	435	Target Neighborhood Hits	124	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

ABTB1_HUMAN
θ value	8.99809 (rank : 414)	NC score	0.264616 (rank : 287)
Query Neighborhood Hits	435	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

C1QR1_HUMAN
θ value	8.99809 (rank : 415)	NC score	0.026390 (rank : 380)
Query Neighborhood Hits	435	Target Neighborhood Hits	493	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CAC1B_MOUSE
θ value	8.99809 (rank : 416)	NC score	0.002235 (rank : 454)
Query Neighborhood Hits	435	Target Neighborhood Hits	351	Shared Neighborhood Hits	29
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CDKL5_HUMAN
θ value	8.99809 (rank : 417)	NC score	0.004973 (rank : 446)
Query Neighborhood Hits	435	Target Neighborhood Hits	967	Shared Neighborhood Hits	29
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

CJ012_HUMAN
θ value	8.99809 (rank : 418)	NC score	0.015159 (rank : 406)
Query Neighborhood Hits	435	Target Neighborhood Hits	467	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

FRS3_MOUSE
θ value	8.99809 (rank : 419)	NC score	0.005748 (rank : 444)
Query Neighborhood Hits	435	Target Neighborhood Hits	168	Shared Neighborhood Hits	13
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

GP112_HUMAN
θ value	8.99809 (rank : 420)	NC score	0.002321 (rank : 452)
Query Neighborhood Hits	435	Target Neighborhood Hits	441	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

ITIH3_HUMAN
θ value	8.99809 (rank : 421)	NC score	0.007097 (rank : 438)
Query Neighborhood Hits	435	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).

K1802_MOUSE
θ value	8.99809 (rank : 422)	NC score	0.020529 (rank : 392)
Query Neighborhood Hits	435	Target Neighborhood Hits	1596	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LAD1_HUMAN
θ value	8.99809 (rank : 423)	NC score	0.028515 (rank : 368)
Query Neighborhood Hits	435	Target Neighborhood Hits	441	Shared Neighborhood Hits	38
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LCP2_MOUSE
θ value	8.99809 (rank : 424)	NC score	0.013178 (rank : 413)
Query Neighborhood Hits	435	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LIPA3_MOUSE
θ value	8.99809 (rank : 425)	NC score	0.027384 (rank : 375)
Query Neighborhood Hits	435	Target Neighborhood Hits	636	Shared Neighborhood Hits	46
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MYLK_MOUSE
θ value	8.99809 (rank : 426)	NC score	0.013979 (rank : 411)
Query Neighborhood Hits	435	Target Neighborhood Hits	1489	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NFAC1_HUMAN
θ value	8.99809 (rank : 427)	NC score	0.012974 (rank : 414)
Query Neighborhood Hits	435	Target Neighborhood Hits	312	Shared Neighborhood Hits	34
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NRX2B_HUMAN
θ value	8.99809 (rank : 428)	NC score	0.007389 (rank : 434)
Query Neighborhood Hits	435	Target Neighborhood Hits	481	Shared Neighborhood Hits	30
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PALM_MOUSE
θ value	8.99809 (rank : 429)	NC score	0.004065 (rank : 448)
Query Neighborhood Hits	435	Target Neighborhood Hits	228	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

PCD12_HUMAN
θ value	8.99809 (rank : 430)	NC score	-0.004240 (rank : 457)
Query Neighborhood Hits	435	Target Neighborhood Hits	203	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NPG4, Q6UXB6, Q96KB8, Q9H7Y6, Q9H8E0	Gene names	PCDH12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

PGCA_HUMAN
θ value	8.99809 (rank : 431)	NC score	0.017139 (rank : 402)
Query Neighborhood Hits	435	Target Neighborhood Hits	821	Shared Neighborhood Hits	50
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PI5PA_MOUSE
θ value	8.99809 (rank : 432)	NC score	0.027542 (rank : 374)
Query Neighborhood Hits	435	Target Neighborhood Hits	331	Shared Neighborhood Hits	42
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SHAN2_HUMAN
θ value	8.99809 (rank : 433)	NC score	0.048253 (rank : 343)
Query Neighborhood Hits	435	Target Neighborhood Hits	346	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	8.99809 (rank : 434)	NC score	0.047811 (rank : 344)
Query Neighborhood Hits	435	Target Neighborhood Hits	446	Shared Neighborhood Hits	48
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

ZN324_HUMAN
θ value	8.99809 (rank : 435)	NC score	-0.013943 (rank : 460)
Query Neighborhood Hits	435	Target Neighborhood Hits	765	Shared Neighborhood Hits	9
SwissProt Accessions	O75467	Gene names	ZNF324
Domain Architecture
Description	Zinc finger protein 324 (Zinc finger protein ZF5128).

ANKF1_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.136257 (rank : 300)
Query Neighborhood Hits	435	Target Neighborhood Hits	126	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKR9_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.211942 (rank : 292)
Query Neighborhood Hits	435	Target Neighborhood Hits	99	Shared Neighborhood Hits	96
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKR9_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.260045 (rank : 288)
Query Neighborhood Hits	435	Target Neighborhood Hits	120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

BASP_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.051119 (rank : 339)
Query Neighborhood Hits	435	Target Neighborhood Hits	260	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CMTA1_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.197494 (rank : 293)
Query Neighborhood Hits	435	Target Neighborhood Hits	217	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CU081_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.092290 (rank : 307)
Query Neighborhood Hits	435	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

DDEF1_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.269623 (rank : 286)
Query Neighborhood Hits	435	Target Neighborhood Hits	592	Shared Neighborhood Hits	204
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DGKZ_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.343437 (rank : 274)
Query Neighborhood Hits	435	Target Neighborhood Hits	542	Shared Neighborhood Hits	205
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

FADD_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.053604 (rank : 334)
Query Neighborhood Hits	435	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q13158, Q14866	Gene names	FADD, MORT1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

FADD_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.058662 (rank : 326)
Query Neighborhood Hits	435	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

IKBL_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.304794 (rank : 279)
Query Neighborhood Hits	435	Target Neighborhood Hits	168	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.297659 (rank : 280)
Query Neighborhood Hits	435	Target Neighborhood Hits	196	Shared Neighborhood Hits	138
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

RSNL2_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.217698 (rank : 291)
Query Neighborhood Hits	435	Target Neighborhood Hits	136	Shared Neighborhood Hits	112
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSNL2_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.183300 (rank : 295)
Query Neighborhood Hits	435	Target Neighborhood Hits	129	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

SPSB2_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.051042 (rank : 340)
Query Neighborhood Hits	435	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	O88838, Q8CBA5, Q91Z15	Gene names	Spsb2, Grcc9, Ssb2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

SRRM1_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.052416 (rank : 336)
Query Neighborhood Hits	435	Target Neighborhood Hits	690	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.054852 (rank : 329)
Query Neighborhood Hits	435	Target Neighborhood Hits	966	Shared Neighborhood Hits	80
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SSB4_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.052697 (rank : 335)
Query Neighborhood Hits	435	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

TRDN_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.051311 (rank : 338)
Query Neighborhood Hits	435	Target Neighborhood Hits	542	Shared Neighborhood Hits	32
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRPC1_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.054487 (rank : 333)
Query Neighborhood Hits	435	Target Neighborhood Hits	91	Shared Neighborhood Hits	55
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC4_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.072913 (rank : 318)
Query Neighborhood Hits	435	Target Neighborhood Hits	140	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.073007 (rank : 317)
Query Neighborhood Hits	435	Target Neighborhood Hits	141	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPV2_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.227402 (rank : 290)
Query Neighborhood Hits	435	Target Neighborhood Hits	130	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TRPV2_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.183988 (rank : 294)
Query Neighborhood Hits	435	Target Neighborhood Hits	111	Shared Neighborhood Hits	93
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

WASIP_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.052339 (rank : 337)
Query Neighborhood Hits	435	Target Neighborhood Hits	458	Shared Neighborhood Hits	57
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

Hits sorted by NC score

ANKS6_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	435	Target Neighborhood Hits	435	Shared Neighborhood Hits	435
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANKS6_HUMAN
NC score	0.989279 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	435	Target Neighborhood Hits	411	Shared Neighborhood Hits	347
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR50_HUMAN
NC score	0.928363 (rank : 3)	θ value	1.3722e-40 (rank : 3)
Query Neighborhood Hits	435	Target Neighborhood Hits	361	Shared Neighborhood Hits	302
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR29_HUMAN
NC score	0.928194 (rank : 4)	θ value	1.42661e-21 (rank : 12)
Query Neighborhood Hits	435	Target Neighborhood Hits	294	Shared Neighborhood Hits	289
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANR16_HUMAN
NC score	0.906991 (rank : 5)	θ value	9.90251e-15 (rank : 42)
Query Neighborhood Hits	435	Target Neighborhood Hits	286	Shared Neighborhood Hits	278
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

PSD10_HUMAN
NC score	0.903016 (rank : 6)	θ value	4.91457e-14 (rank : 49)
Query Neighborhood Hits	435	Target Neighborhood Hits	301	Shared Neighborhood Hits	287
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
NC score	0.902266 (rank : 7)	θ value	1.42992e-13 (rank : 53)
Query Neighborhood Hits	435	Target Neighborhood Hits	293	Shared Neighborhood Hits	287
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

FANK1_HUMAN
NC score	0.901928 (rank : 8)	θ value	1.63225e-17 (rank : 24)
Query Neighborhood Hits	435	Target Neighborhood Hits	326	Shared Neighborhood Hits	284
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

FANK1_MOUSE
NC score	0.900927 (rank : 9)	θ value	3.63628e-17 (rank : 26)
Query Neighborhood Hits	435	Target Neighborhood Hits	325	Shared Neighborhood Hits	280
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANK1_HUMAN
NC score	0.899453 (rank : 10)	θ value	6.82597e-32 (rank : 5)
Query Neighborhood Hits	435	Target Neighborhood Hits	416	Shared Neighborhood Hits	298
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANR44_HUMAN
NC score	0.897688 (rank : 11)	θ value	1.16704e-23 (rank : 10)
Query Neighborhood Hits	435	Target Neighborhood Hits	318	Shared Neighborhood Hits	297
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANK1_MOUSE
NC score	0.897453 (rank : 12)	θ value	4.00176e-32 (rank : 4)
Query Neighborhood Hits	435	Target Neighborhood Hits	430	Shared Neighborhood Hits	298
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ASB3_HUMAN
NC score	0.895099 (rank : 13)	θ value	4.02038e-16 (rank : 30)
Query Neighborhood Hits	435	Target Neighborhood Hits	316	Shared Neighborhood Hits	291
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANR28_MOUSE
NC score	0.894993 (rank : 14)	θ value	1.86321e-21 (rank : 13)
Query Neighborhood Hits	435	Target Neighborhood Hits	314	Shared Neighborhood Hits	294
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ASB3_MOUSE
NC score	0.893992 (rank : 15)	θ value	9.90251e-15 (rank : 43)
Query Neighborhood Hits	435	Target Neighborhood Hits	316	Shared Neighborhood Hits	291
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANR28_HUMAN
NC score	0.893964 (rank : 16)	θ value	2.06002e-20 (rank : 16)
Query Neighborhood Hits	435	Target Neighborhood Hits	314	Shared Neighborhood Hits	294
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANKR6_HUMAN
NC score	0.892547 (rank : 17)	θ value	7.58209e-15 (rank : 40)
Query Neighborhood Hits	435	Target Neighborhood Hits	439	Shared Neighborhood Hits	288
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

TNKS1_HUMAN
NC score	0.891614 (rank : 18)	θ value	8.65492e-19 (rank : 20)
Query Neighborhood Hits	435	Target Neighborhood Hits	477	Shared Neighborhood Hits	322
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TNKS2_HUMAN
NC score	0.891487 (rank : 19)	θ value	7.32683e-18 (rank : 23)
Query Neighborhood Hits	435	Target Neighborhood Hits	361	Shared Neighborhood Hits	304
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR52_MOUSE
NC score	0.889324 (rank : 20)	θ value	2.06002e-20 (rank : 17)
Query Neighborhood Hits	435	Target Neighborhood Hits	318	Shared Neighborhood Hits	296
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
NC score	0.888567 (rank : 21)	θ value	1.33526e-19 (rank : 18)
Query Neighborhood Hits	435	Target Neighborhood Hits	322	Shared Neighborhood Hits	296
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR39_HUMAN
NC score	0.887349 (rank : 22)	θ value	3.89403e-11 (rank : 75)
Query Neighborhood Hits	435	Target Neighborhood Hits	285	Shared Neighborhood Hits	277
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANK3_HUMAN
NC score	0.886865 (rank : 23)	θ value	4.89182e-30 (rank : 6)
Query Neighborhood Hits	435	Target Neighborhood Hits	853	Shared Neighborhood Hits	318
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANKS3_MOUSE
NC score	0.886714 (rank : 24)	θ value	1.058e-16 (rank : 27)
Query Neighborhood Hits	435	Target Neighborhood Hits	355	Shared Neighborhood Hits	287
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB2_HUMAN
NC score	0.886518 (rank : 25)	θ value	1.80466e-16 (rank : 28)
Query Neighborhood Hits	435	Target Neighborhood Hits	309	Shared Neighborhood Hits	287
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB2_MOUSE
NC score	0.884863 (rank : 26)	θ value	1.92812e-18 (rank : 22)
Query Neighborhood Hits	435	Target Neighborhood Hits	321	Shared Neighborhood Hits	290
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR39_MOUSE
NC score	0.884765 (rank : 27)	θ value	6.64225e-11 (rank : 80)
Query Neighborhood Hits	435	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

INVS_HUMAN
NC score	0.884400 (rank : 28)	θ value	5.8054e-15 (rank : 39)
Query Neighborhood Hits	435	Target Neighborhood Hits	455	Shared Neighborhood Hits	300
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ANKS3_HUMAN
NC score	0.882511 (rank : 29)	θ value	5.25075e-16 (rank : 31)
Query Neighborhood Hits	435	Target Neighborhood Hits	355	Shared Neighborhood Hits	288
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB7_MOUSE
NC score	0.881062 (rank : 30)	θ value	3.52202e-12 (rank : 61)
Query Neighborhood Hits	435	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANR23_MOUSE
NC score	0.880256 (rank : 31)	θ value	1.29331e-14 (rank : 45)
Query Neighborhood Hits	435	Target Neighborhood Hits	296	Shared Neighborhood Hits	283
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ASB7_HUMAN
NC score	0.879672 (rank : 32)	θ value	2.28291e-11 (rank : 69)
Query Neighborhood Hits	435	Target Neighborhood Hits	296	Shared Neighborhood Hits	282
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANKR2_MOUSE
NC score	0.876801 (rank : 33)	θ value	1.74796e-11 (rank : 66)
Query Neighborhood Hits	435	Target Neighborhood Hits	312	Shared Neighborhood Hits	285
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

INVS_MOUSE
NC score	0.876498 (rank : 34)	θ value	9.90251e-15 (rank : 44)
Query Neighborhood Hits	435	Target Neighborhood Hits	609	Shared Neighborhood Hits	307
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANR23_HUMAN
NC score	0.874781 (rank : 35)	θ value	1.2105e-12 (rank : 57)
Query Neighborhood Hits	435	Target Neighborhood Hits	291	Shared Neighborhood Hits	282
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANKR2_HUMAN
NC score	0.874764 (rank : 36)	θ value	3.89403e-11 (rank : 74)
Query Neighborhood Hits	435	Target Neighborhood Hits	321	Shared Neighborhood Hits	285
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ASB10_MOUSE
NC score	0.874271 (rank : 37)	θ value	2.43908e-13 (rank : 55)
Query Neighborhood Hits	435	Target Neighborhood Hits	301	Shared Neighborhood Hits	282
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

GABP2_MOUSE
NC score	0.873696 (rank : 38)	θ value	2.28291e-11 (rank : 71)
Query Neighborhood Hits	435	Target Neighborhood Hits	429	Shared Neighborhood Hits	294
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ASB10_HUMAN
NC score	0.873625 (rank : 39)	θ value	1.33837e-11 (rank : 65)
Query Neighborhood Hits	435	Target Neighborhood Hits	291	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

GABP2_HUMAN
NC score	0.871807 (rank : 40)	θ value	7.84624e-12 (rank : 63)
Query Neighborhood Hits	435	Target Neighborhood Hits	454	Shared Neighborhood Hits	293
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP3_MOUSE
NC score	0.870484 (rank : 41)	θ value	8.67504e-11 (rank : 83)
Query Neighborhood Hits	435	Target Neighborhood Hits	330	Shared Neighborhood Hits	279
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

TRPA1_MOUSE
NC score	0.870100 (rank : 42)	θ value	8.95645e-16 (rank : 36)
Query Neighborhood Hits	435	Target Neighborhood Hits	343	Shared Neighborhood Hits	291
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TRPA1_HUMAN
NC score	0.869241 (rank : 43)	θ value	2.20605e-14 (rank : 47)
Query Neighborhood Hits	435	Target Neighborhood Hits	339	Shared Neighborhood Hits	294
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ANR42_HUMAN
NC score	0.867835 (rank : 44)	θ value	4.76016e-09 (rank : 116)
Query Neighborhood Hits	435	Target Neighborhood Hits	284	Shared Neighborhood Hits	277
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANKR1_HUMAN
NC score	0.866384 (rank : 45)	θ value	9.59137e-10 (rank : 103)
Query Neighborhood Hits	435	Target Neighborhood Hits	308	Shared Neighborhood Hits	279
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANR42_MOUSE
NC score	0.865848 (rank : 46)	θ value	6.87365e-08 (rank : 143)
Query Neighborhood Hits	435	Target Neighborhood Hits	334	Shared Neighborhood Hits	277
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASZ1_MOUSE
NC score	0.865459 (rank : 47)	θ value	2.28291e-11 (rank : 70)
Query Neighborhood Hits	435	Target Neighborhood Hits	319	Shared Neighborhood Hits	276
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

MTPN_MOUSE
NC score	0.865157 (rank : 48)	θ value	6.87365e-08 (rank : 145)
Query Neighborhood Hits	435	Target Neighborhood Hits	269	Shared Neighborhood Hits	268
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

MTPN_HUMAN
NC score	0.864470 (rank : 49)	θ value	1.38499e-08 (rank : 126)
Query Neighborhood Hits	435	Target Neighborhood Hits	269	Shared Neighborhood Hits	268
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ANKR1_MOUSE
NC score	0.863891 (rank : 50)	θ value	1.25267e-09 (rank : 107)
Query Neighborhood Hits	435	Target Neighborhood Hits	316	Shared Neighborhood Hits	285
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ASZ1_HUMAN
NC score	0.862787 (rank : 51)	θ value	1.74796e-11 (rank : 67)
Query Neighborhood Hits	435	Target Neighborhood Hits	341	Shared Neighborhood Hits	274
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

PP16A_MOUSE
NC score	0.858427 (rank : 52)	θ value	2.0648e-12 (rank : 60)
Query Neighborhood Hits	435	Target Neighborhood Hits	318	Shared Neighborhood Hits	282
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

CDN2C_MOUSE
NC score	0.857251 (rank : 53)	θ value	2.36244e-08 (rank : 133)
Query Neighborhood Hits	435	Target Neighborhood Hits	270	Shared Neighborhood Hits	267
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

MYPT1_MOUSE
NC score	0.857217 (rank : 54)	θ value	5.25075e-16 (rank : 33)
Query Neighborhood Hits	435	Target Neighborhood Hits	539	Shared Neighborhood Hits	295
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ANR49_MOUSE
NC score	0.856853 (rank : 55)	θ value	7.59969e-07 (rank : 155)
Query Neighborhood Hits	435	Target Neighborhood Hits	285	Shared Neighborhood Hits	279
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ASB14_MOUSE
NC score	0.855768 (rank : 56)	θ value	2.35696e-16 (rank : 29)
Query Neighborhood Hits	435	Target Neighborhood Hits	293	Shared Neighborhood Hits	277
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ANR49_HUMAN
NC score	0.855424 (rank : 57)	θ value	1.80886e-08 (rank : 128)
Query Neighborhood Hits	435	Target Neighborhood Hits	282	Shared Neighborhood Hits	276
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ANKR5_MOUSE
NC score	0.855072 (rank : 58)	θ value	3.29651e-10 (rank : 91)
Query Neighborhood Hits	435	Target Neighborhood Hits	298	Shared Neighborhood Hits	281
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKR5_HUMAN
NC score	0.854859 (rank : 59)	θ value	7.34386e-10 (rank : 101)
Query Neighborhood Hits	435	Target Neighborhood Hits	297	Shared Neighborhood Hits	280
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKS1_HUMAN
NC score	0.854610 (rank : 60)	θ value	7.58209e-15 (rank : 41)
Query Neighborhood Hits	435	Target Neighborhood Hits	438	Shared Neighborhood Hits	310
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

CDN2C_HUMAN
NC score	0.854306 (rank : 61)	θ value	3.08544e-08 (rank : 136)
Query Neighborhood Hits	435	Target Neighborhood Hits	262	Shared Neighborhood Hits	261
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ASB15_HUMAN
NC score	0.854146 (rank : 62)	θ value	2.52405e-10 (rank : 89)
Query Neighborhood Hits	435	Target Neighborhood Hits	305	Shared Neighborhood Hits	276
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

BCL3_HUMAN
NC score	0.853993 (rank : 63)	θ value	1.38499e-08 (rank : 124)
Query Neighborhood Hits	435	Target Neighborhood Hits	324	Shared Neighborhood Hits	285
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ANRA2_HUMAN
NC score	0.853152 (rank : 64)	θ value	3.29651e-10 (rank : 92)
Query Neighborhood Hits	435	Target Neighborhood Hits	288	Shared Neighborhood Hits	281
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

CDN2D_HUMAN
NC score	0.851614 (rank : 65)	θ value	8.97725e-08 (rank : 146)
Query Neighborhood Hits	435	Target Neighborhood Hits	268	Shared Neighborhood Hits	267
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANRA2_MOUSE
NC score	0.851514 (rank : 66)	θ value	3.29651e-10 (rank : 93)
Query Neighborhood Hits	435	Target Neighborhood Hits	287	Shared Neighborhood Hits	280
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB13_HUMAN
NC score	0.851144 (rank : 67)	θ value	9.92553e-07 (rank : 159)
Query Neighborhood Hits	435	Target Neighborhood Hits	293	Shared Neighborhood Hits	279
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_MOUSE
NC score	0.851082 (rank : 68)	θ value	7.59969e-07 (rank : 156)
Query Neighborhood Hits	435	Target Neighborhood Hits	293	Shared Neighborhood Hits	277
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

RFXK_HUMAN
NC score	0.849657 (rank : 69)	θ value	1.133e-10 (rank : 84)
Query Neighborhood Hits	435	Target Neighborhood Hits	282	Shared Neighborhood Hits	264
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

BCL3_MOUSE
NC score	0.848940 (rank : 70)	θ value	1.38499e-08 (rank : 125)
Query Neighborhood Hits	435	Target Neighborhood Hits	388	Shared Neighborhood Hits	282
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ASB8_HUMAN
NC score	0.848099 (rank : 71)	θ value	0.00020696 (rank : 219)
Query Neighborhood Hits	435	Target Neighborhood Hits	294	Shared Neighborhood Hits	277
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

PP16A_HUMAN
NC score	0.847816 (rank : 72)	θ value	5.08577e-11 (rank : 77)
Query Neighborhood Hits	435	Target Neighborhood Hits	340	Shared Neighborhood Hits	280
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ASB8_MOUSE
NC score	0.847726 (rank : 73)	θ value	9.29e-05 (rank : 213)
Query Neighborhood Hits	435	Target Neighborhood Hits	293	Shared Neighborhood Hits	275
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

PP16B_HUMAN
NC score	0.847231 (rank : 74)	θ value	1.02475e-11 (rank : 64)
Query Neighborhood Hits	435	Target Neighborhood Hits	307	Shared Neighborhood Hits	282
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

CDN2D_MOUSE
NC score	0.846330 (rank : 75)	θ value	3.08544e-08 (rank : 137)
Query Neighborhood Hits	435	Target Neighborhood Hits	267	Shared Neighborhood Hits	263
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

MIB1_HUMAN
NC score	0.845862 (rank : 76)	θ value	1.52774e-15 (rank : 37)
Query Neighborhood Hits	435	Target Neighborhood Hits	470	Shared Neighborhood Hits	292
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

PP16B_MOUSE
NC score	0.845785 (rank : 77)	θ value	2.28291e-11 (rank : 73)
Query Neighborhood Hits	435	Target Neighborhood Hits	302	Shared Neighborhood Hits	280
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

MIB1_MOUSE
NC score	0.845226 (rank : 78)	θ value	1.52774e-15 (rank : 38)
Query Neighborhood Hits	435	Target Neighborhood Hits	471	Shared Neighborhood Hits	292
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ANKS1_MOUSE
NC score	0.843609 (rank : 79)	θ value	1.42992e-13 (rank : 52)
Query Neighborhood Hits	435	Target Neighborhood Hits	453	Shared Neighborhood Hits	306
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ASB16_MOUSE
NC score	0.842537 (rank : 80)	θ value	6.64225e-11 (rank : 81)
Query Neighborhood Hits	435	Target Neighborhood Hits	306	Shared Neighborhood Hits	275
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

RN5A_HUMAN
NC score	0.841652 (rank : 81)	θ value	1.42992e-13 (rank : 54)
Query Neighborhood Hits	435	Target Neighborhood Hits	608	Shared Neighborhood Hits	284
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

RFXK_MOUSE
NC score	0.840233 (rank : 82)	θ value	3.08544e-08 (rank : 138)
Query Neighborhood Hits	435	Target Neighborhood Hits	273	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ASB15_MOUSE
NC score	0.840026 (rank : 83)	θ value	1.80886e-08 (rank : 129)
Query Neighborhood Hits	435	Target Neighborhood Hits	292	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANKR7_HUMAN
NC score	0.839707 (rank : 84)	θ value	2.79066e-09 (rank : 113)
Query Neighborhood Hits	435	Target Neighborhood Hits	286	Shared Neighborhood Hits	278
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

MYPT1_HUMAN
NC score	0.837201 (rank : 85)	θ value	8.95645e-16 (rank : 35)
Query Neighborhood Hits	435	Target Neighborhood Hits	723	Shared Neighborhood Hits	292
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ANR46_HUMAN
NC score	0.835989 (rank : 86)	θ value	6.87365e-08 (rank : 144)
Query Neighborhood Hits	435	Target Neighborhood Hits	281	Shared Neighborhood Hits	270
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

MYPT2_HUMAN
NC score	0.835433 (rank : 87)	θ value	6.41864e-14 (rank : 50)
Query Neighborhood Hits	435	Target Neighborhood Hits	707	Shared Neighborhood Hits	295
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ASB16_HUMAN
NC score	0.834925 (rank : 88)	θ value	1.29631e-06 (rank : 162)
Query Neighborhood Hits	435	Target Neighborhood Hits	286	Shared Neighborhood Hits	266
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANK2_HUMAN
NC score	0.834888 (rank : 89)	θ value	7.80994e-28 (rank : 8)
Query Neighborhood Hits	435	Target Neighborhood Hits	1615	Shared Neighborhood Hits	352
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASB1_HUMAN
NC score	0.834500 (rank : 90)	θ value	3.29651e-10 (rank : 94)
Query Neighborhood Hits	435	Target Neighborhood Hits	291	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

CSKI2_MOUSE
NC score	0.833672 (rank : 91)	θ value	1.09485e-13 (rank : 51)
Query Neighborhood Hits	435	Target Neighborhood Hits	812	Shared Neighborhood Hits	333
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CT086_HUMAN
NC score	0.833352 (rank : 92)	θ value	3.19293e-05 (rank : 198)
Query Neighborhood Hits	435	Target Neighborhood Hits	277	Shared Neighborhood Hits	269
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

CSKI2_HUMAN
NC score	0.831910 (rank : 93)	θ value	4.16044e-13 (rank : 56)
Query Neighborhood Hits	435	Target Neighborhood Hits	747	Shared Neighborhood Hits	331
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB1_MOUSE
NC score	0.831771 (rank : 94)	θ value	2.52405e-10 (rank : 90)
Query Neighborhood Hits	435	Target Neighborhood Hits	292	Shared Neighborhood Hits	278
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB12_MOUSE
NC score	0.831037 (rank : 95)	θ value	5.08577e-11 (rank : 76)
Query Neighborhood Hits	435	Target Neighborhood Hits	261	Shared Neighborhood Hits	259
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

PA2G6_MOUSE
NC score	0.830459 (rank : 96)	θ value	2.44474e-05 (rank : 197)
Query Neighborhood Hits	435	Target Neighborhood Hits	293	Shared Neighborhood Hits	281
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB12_HUMAN
NC score	0.829642 (rank : 97)	θ value	1.17247e-07 (rank : 148)
Query Neighborhood Hits	435	Target Neighborhood Hits	263	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

MIB2_HUMAN
NC score	0.829420 (rank : 98)	θ value	5.62301e-10 (rank : 99)
Query Neighborhood Hits	435	Target Neighborhood Hits	438	Shared Neighborhood Hits	287
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ANR46_MOUSE
NC score	0.828624 (rank : 99)	θ value	2.61198e-07 (rank : 152)
Query Neighborhood Hits	435	Target Neighborhood Hits	274	Shared Neighborhood Hits	263
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

MIB2_MOUSE
NC score	0.828382 (rank : 100)	θ value	9.59137e-10 (rank : 104)
Query Neighborhood Hits	435	Target Neighborhood Hits	409	Shared Neighborhood Hits	280
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

IKBA_HUMAN
NC score	0.827721 (rank : 101)	θ value	1.29631e-06 (rank : 163)
Query Neighborhood Hits	435	Target Neighborhood Hits	280	Shared Neighborhood Hits	269
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

PA2G6_HUMAN
NC score	0.827661 (rank : 102)	θ value	2.88788e-06 (rank : 176)
Query Neighborhood Hits	435	Target Neighborhood Hits	284	Shared Neighborhood Hits	275
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

CSKI1_HUMAN
NC score	0.826338 (rank : 103)	θ value	5.25075e-16 (rank : 32)
Query Neighborhood Hits	435	Target Neighborhood Hits	997	Shared Neighborhood Hits	341
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
NC score	0.825115 (rank : 104)	θ value	6.85773e-16 (rank : 34)
Query Neighborhood Hits	435	Target Neighborhood Hits	1031	Shared Neighborhood Hits	345
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

IKBE_MOUSE
NC score	0.823049 (rank : 105)	θ value	2.36244e-08 (rank : 134)
Query Neighborhood Hits	435	Target Neighborhood Hits	308	Shared Neighborhood Hits	272
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

BARD1_HUMAN
NC score	0.822945 (rank : 106)	θ value	4.59992e-12 (rank : 62)
Query Neighborhood Hits	435	Target Neighborhood Hits	427	Shared Neighborhood Hits	289
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ASB9_HUMAN
NC score	0.822030 (rank : 107)	θ value	4.76016e-09 (rank : 117)
Query Neighborhood Hits	435	Target Neighborhood Hits	267	Shared Neighborhood Hits	259
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

BARD1_MOUSE
NC score	0.821476 (rank : 108)	θ value	1.74796e-11 (rank : 68)
Query Neighborhood Hits	435	Target Neighborhood Hits	411	Shared Neighborhood Hits	285
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ASB11_MOUSE
NC score	0.821344 (rank : 109)	θ value	2.52405e-10 (rank : 88)
Query Neighborhood Hits	435	Target Neighborhood Hits	271	Shared Neighborhood Hits	257
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB11_HUMAN
NC score	0.819768 (rank : 110)	θ value	7.34386e-10 (rank : 102)
Query Neighborhood Hits	435	Target Neighborhood Hits	271	Shared Neighborhood Hits	259
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

IKBA_MOUSE
NC score	0.815204 (rank : 111)	θ value	2.88788e-06 (rank : 175)
Query Neighborhood Hits	435	Target Neighborhood Hits	283	Shared Neighborhood Hits	270
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ASB5_HUMAN
NC score	0.813815 (rank : 112)	θ value	2.21117e-06 (rank : 171)
Query Neighborhood Hits	435	Target Neighborhood Hits	283	Shared Neighborhood Hits	269
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

EHMT1_HUMAN
NC score	0.813399 (rank : 113)	θ value	5.62301e-10 (rank : 97)
Query Neighborhood Hits	435	Target Neighborhood Hits	417	Shared Neighborhood Hits	299
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ACBD6_MOUSE
NC score	0.812771 (rank : 114)	θ value	3.77169e-06 (rank : 177)
Query Neighborhood Hits	435	Target Neighborhood Hits	305	Shared Neighborhood Hits	283
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ACBD6_HUMAN
NC score	0.810944 (rank : 115)	θ value	6.43352e-06 (rank : 182)
Query Neighborhood Hits	435	Target Neighborhood Hits	304	Shared Neighborhood Hits	281
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ASB5_MOUSE
NC score	0.808596 (rank : 116)	θ value	1.43324e-05 (rank : 188)
Query Neighborhood Hits	435	Target Neighborhood Hits	266	Shared Neighborhood Hits	257
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANR10_HUMAN
NC score	0.806738 (rank : 117)	θ value	5.44631e-05 (rank : 201)
Query Neighborhood Hits	435	Target Neighborhood Hits	289	Shared Neighborhood Hits	265
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR22_HUMAN
NC score	0.805642 (rank : 118)	θ value	0.000602161 (rank : 228)
Query Neighborhood Hits	435	Target Neighborhood Hits	243	Shared Neighborhood Hits	239
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR10_MOUSE
NC score	0.803493 (rank : 119)	θ value	0.000786445 (rank : 231)
Query Neighborhood Hits	435	Target Neighborhood Hits	273	Shared Neighborhood Hits	265
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR35_HUMAN
NC score	0.803181 (rank : 120)	θ value	1.9326e-10 (rank : 87)
Query Neighborhood Hits	435	Target Neighborhood Hits	784	Shared Neighborhood Hits	297
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASB9_MOUSE
NC score	0.802909 (rank : 121)	θ value	7.1131e-05 (rank : 207)
Query Neighborhood Hits	435	Target Neighborhood Hits	257	Shared Neighborhood Hits	252
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

AN36B_HUMAN
NC score	0.801375 (rank : 122)	θ value	1.87187e-05 (rank : 191)
Query Neighborhood Hits	435	Target Neighborhood Hits	294	Shared Neighborhood Hits	280
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

IKBB_MOUSE
NC score	0.800789 (rank : 123)	θ value	6.21693e-09 (rank : 120)
Query Neighborhood Hits	435	Target Neighborhood Hits	284	Shared Neighborhood Hits	273
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

EHMT2_HUMAN
NC score	0.800730 (rank : 124)	θ value	8.11959e-09 (rank : 122)
Query Neighborhood Hits	435	Target Neighborhood Hits	498	Shared Neighborhood Hits	302
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

IKBB_HUMAN
NC score	0.799133 (rank : 125)	θ value	5.62301e-10 (rank : 98)
Query Neighborhood Hits	435	Target Neighborhood Hits	284	Shared Neighborhood Hits	268
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

IKBE_HUMAN
NC score	0.796479 (rank : 126)	θ value	4.1701e-05 (rank : 200)
Query Neighborhood Hits	435	Target Neighborhood Hits	288	Shared Neighborhood Hits	263
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

RN5A_MOUSE
NC score	0.795765 (rank : 127)	θ value	2.7842e-17 (rank : 25)
Query Neighborhood Hits	435	Target Neighborhood Hits	899	Shared Neighborhood Hits	297
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASB4_HUMAN
NC score	0.795763 (rank : 128)	θ value	0.00228821 (rank : 239)
Query Neighborhood Hits	435	Target Neighborhood Hits	264	Shared Neighborhood Hits	255
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ANKY2_HUMAN
NC score	0.793027 (rank : 129)	θ value	6.21693e-09 (rank : 119)
Query Neighborhood Hits	435	Target Neighborhood Hits	306	Shared Neighborhood Hits	264
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ASB4_MOUSE
NC score	0.788512 (rank : 130)	θ value	0.0193708 (rank : 257)
Query Neighborhood Hits	435	Target Neighborhood Hits	265	Shared Neighborhood Hits	255
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

EHMT2_MOUSE
NC score	0.788285 (rank : 131)	θ value	1.63604e-09 (rank : 111)
Query Neighborhood Hits	435	Target Neighborhood Hits	750	Shared Neighborhood Hits	314
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

POTE8_HUMAN
NC score	0.787807 (rank : 132)	θ value	4.0297e-08 (rank : 141)
Query Neighborhood Hits	435	Target Neighborhood Hits	337	Shared Neighborhood Hits	286
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ANFY1_MOUSE
NC score	0.780699 (rank : 133)	θ value	4.76016e-09 (rank : 115)
Query Neighborhood Hits	435	Target Neighborhood Hits	480	Shared Neighborhood Hits	293
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_HUMAN
NC score	0.780207 (rank : 134)	θ value	1.25267e-09 (rank : 106)
Query Neighborhood Hits	435	Target Neighborhood Hits	480	Shared Neighborhood Hits	286
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR19_HUMAN
NC score	0.774913 (rank : 135)	θ value	1.69304e-06 (rank : 168)
Query Neighborhood Hits	435	Target Neighborhood Hits	276	Shared Neighborhood Hits	266
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANR47_MOUSE
NC score	0.773805 (rank : 136)	θ value	1.25267e-09 (rank : 109)
Query Neighborhood Hits	435	Target Neighborhood Hits	350	Shared Neighborhood Hits	263
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANKY2_MOUSE
NC score	0.771693 (rank : 137)	θ value	1.25267e-09 (rank : 108)
Query Neighborhood Hits	435	Target Neighborhood Hits	316	Shared Neighborhood Hits	261
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR15_HUMAN
NC score	0.770909 (rank : 138)	θ value	3.08544e-08 (rank : 135)
Query Neighborhood Hits	435	Target Neighborhood Hits	478	Shared Neighborhood Hits	277
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

USH1G_HUMAN
NC score	0.769450 (rank : 139)	θ value	7.1131e-05 (rank : 211)
Query Neighborhood Hits	435	Target Neighborhood Hits	267	Shared Neighborhood Hits	263
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
NC score	0.769362 (rank : 140)	θ value	7.1131e-05 (rank : 212)
Query Neighborhood Hits	435	Target Neighborhood Hits	271	Shared Neighborhood Hits	263
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ANS4B_HUMAN
NC score	0.767912 (rank : 141)	θ value	7.1131e-05 (rank : 205)
Query Neighborhood Hits	435	Target Neighborhood Hits	289	Shared Neighborhood Hits	260
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANR32_HUMAN
NC score	0.766672 (rank : 142)	θ value	0.00134147 (rank : 236)
Query Neighborhood Hits	435	Target Neighborhood Hits	270	Shared Neighborhood Hits	259
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR11_HUMAN
NC score	0.763858 (rank : 143)	θ value	6.64225e-11 (rank : 78)
Query Neighborhood Hits	435	Target Neighborhood Hits	1289	Shared Neighborhood Hits	318
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR41_HUMAN
NC score	0.763005 (rank : 144)	θ value	0.000786445 (rank : 232)
Query Neighborhood Hits	435	Target Neighborhood Hits	332	Shared Neighborhood Hits	252
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

CTTB2_HUMAN
NC score	0.761092 (rank : 145)	θ value	2.0648e-12 (rank : 59)
Query Neighborhood Hits	435	Target Neighborhood Hits	1061	Shared Neighborhood Hits	310
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANS4B_MOUSE
NC score	0.757982 (rank : 146)	θ value	2.44474e-05 (rank : 196)
Query Neighborhood Hits	435	Target Neighborhood Hits	294	Shared Neighborhood Hits	256
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

AN36A_HUMAN
NC score	0.757564 (rank : 147)	θ value	0.0193708 (rank : 255)
Query Neighborhood Hits	435	Target Neighborhood Hits	271	Shared Neighborhood Hits	263
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ZDH17_HUMAN
NC score	0.756946 (rank : 148)	θ value	6.21693e-09 (rank : 121)
Query Neighborhood Hits	435	Target Neighborhood Hits	334	Shared Neighborhood Hits	279
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANR32_MOUSE
NC score	0.756430 (rank : 149)	θ value	0.00509761 (rank : 243)
Query Neighborhood Hits	435	Target Neighborhood Hits	285	Shared Neighborhood Hits	258
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ASB6_HUMAN
NC score	0.753942 (rank : 150)	θ value	0.000602161 (rank : 229)
Query Neighborhood Hits	435	Target Neighborhood Hits	256	Shared Neighborhood Hits	246
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASB6_MOUSE
NC score	0.753685 (rank : 151)	θ value	7.1131e-05 (rank : 206)
Query Neighborhood Hits	435	Target Neighborhood Hits	264	Shared Neighborhood Hits	246
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR47_HUMAN
NC score	0.753302 (rank : 152)	θ value	4.30538e-10 (rank : 95)
Query Neighborhood Hits	435	Target Neighborhood Hits	369	Shared Neighborhood Hits	261
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ZDH17_MOUSE
NC score	0.750778 (rank : 153)	θ value	1.38499e-08 (rank : 127)
Query Neighborhood Hits	435	Target Neighborhood Hits	328	Shared Neighborhood Hits	273
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

BCOR_MOUSE
NC score	0.746294 (rank : 154)	θ value	1.80886e-08 (rank : 130)
Query Neighborhood Hits	435	Target Neighborhood Hits	521	Shared Neighborhood Hits	290
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ZDH13_HUMAN
NC score	0.745144 (rank : 155)	θ value	1.53129e-07 (rank : 150)
Query Neighborhood Hits	435	Target Neighborhood Hits	322	Shared Neighborhood Hits	272
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

POT15_HUMAN
NC score	0.744036 (rank : 156)	θ value	2.28291e-11 (rank : 72)
Query Neighborhood Hits	435	Target Neighborhood Hits	893	Shared Neighborhood Hits	294
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ANR21_HUMAN
NC score	0.742361 (rank : 157)	θ value	1.9326e-10 (rank : 86)
Query Neighborhood Hits	435	Target Neighborhood Hits	864	Shared Neighborhood Hits	295
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

CLPB_MOUSE
NC score	0.740884 (rank : 158)	θ value	6.64225e-11 (rank : 82)
Query Neighborhood Hits	435	Target Neighborhood Hits	289	Shared Neighborhood Hits	250
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ZDH13_MOUSE
NC score	0.740047 (rank : 159)	θ value	3.77169e-06 (rank : 179)
Query Neighborhood Hits	435	Target Neighborhood Hits	329	Shared Neighborhood Hits	275
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

BCOR_HUMAN
NC score	0.736938 (rank : 160)	θ value	2.36244e-08 (rank : 132)
Query Neighborhood Hits	435	Target Neighborhood Hits	609	Shared Neighborhood Hits	289
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANR12_HUMAN
NC score	0.733674 (rank : 161)	θ value	6.64225e-11 (rank : 79)
Query Neighborhood Hits	435	Target Neighborhood Hits	1081	Shared Neighborhood Hits	293
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR33_MOUSE
NC score	0.731184 (rank : 162)	θ value	9.92553e-07 (rank : 158)
Query Neighborhood Hits	435	Target Neighborhood Hits	225	Shared Neighborhood Hits	222
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

NFKB1_HUMAN
NC score	0.730545 (rank : 163)	θ value	3.64472e-09 (rank : 114)
Query Neighborhood Hits	435	Target Neighborhood Hits	306	Shared Neighborhood Hits	271
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

NFKB1_MOUSE
NC score	0.727378 (rank : 164)	θ value	9.59137e-10 (rank : 105)
Query Neighborhood Hits	435	Target Neighborhood Hits	300	Shared Neighborhood Hits	265
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

POT14_HUMAN
NC score	0.725041 (rank : 165)	θ value	1.09739e-05 (rank : 187)
Query Neighborhood Hits	435	Target Neighborhood Hits	403	Shared Neighborhood Hits	272
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ANR33_HUMAN
NC score	0.724478 (rank : 166)	θ value	5.81887e-07 (rank : 154)
Query Neighborhood Hits	435	Target Neighborhood Hits	215	Shared Neighborhood Hits	212
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR25_HUMAN
NC score	0.721591 (rank : 167)	θ value	3.77169e-06 (rank : 178)
Query Neighborhood Hits	435	Target Neighborhood Hits	350	Shared Neighborhood Hits	269
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

CD2A1_MOUSE
NC score	0.720976 (rank : 168)	θ value	2.21117e-06 (rank : 172)
Query Neighborhood Hits	435	Target Neighborhood Hits	206	Shared Neighborhood Hits	203
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

SHAN1_HUMAN
NC score	0.720099 (rank : 169)	θ value	1.17247e-07 (rank : 149)
Query Neighborhood Hits	435	Target Neighborhood Hits	1041	Shared Neighborhood Hits	320
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANR37_HUMAN
NC score	0.716578 (rank : 170)	θ value	0.0148317 (rank : 251)
Query Neighborhood Hits	435	Target Neighborhood Hits	247	Shared Neighborhood Hits	243
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

NFKB2_HUMAN
NC score	0.714542 (rank : 171)	θ value	0.000270298 (rank : 223)
Query Neighborhood Hits	435	Target Neighborhood Hits	325	Shared Neighborhood Hits	277
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

SNCAP_HUMAN
NC score	0.709647 (rank : 172)	θ value	0.00869519 (rank : 246)
Query Neighborhood Hits	435	Target Neighborhood Hits	313	Shared Neighborhood Hits	240
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

MPP8_HUMAN
NC score	0.708421 (rank : 173)	θ value	1.58096e-12 (rank : 58)
Query Neighborhood Hits	435	Target Neighborhood Hits	948	Shared Neighborhood Hits	268
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ANR25_MOUSE
NC score	0.707289 (rank : 174)	θ value	6.43352e-06 (rank : 183)
Query Neighborhood Hits	435	Target Neighborhood Hits	398	Shared Neighborhood Hits	269
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR38_HUMAN
NC score	0.698440 (rank : 175)	θ value	1.87187e-05 (rank : 192)
Query Neighborhood Hits	435	Target Neighborhood Hits	443	Shared Neighborhood Hits	248
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

NFKB2_MOUSE
NC score	0.696289 (rank : 176)	θ value	0.00390308 (rank : 241)
Query Neighborhood Hits	435	Target Neighborhood Hits	326	Shared Neighborhood Hits	270
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR37_MOUSE
NC score	0.681781 (rank : 177)	θ value	1.06291 (rank : 326)
Query Neighborhood Hits	435	Target Neighborhood Hits	237	Shared Neighborhood Hits	234
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

POT22_HUMAN
NC score	0.681717 (rank : 178)	θ value	9.29e-05 (rank : 214)
Query Neighborhood Hits	435	Target Neighborhood Hits	266	Shared Neighborhood Hits	254
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

KRIT1_MOUSE
NC score	0.674731 (rank : 179)	θ value	0.000461057 (rank : 225)
Query Neighborhood Hits	435	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

CDN2B_MOUSE
NC score	0.674054 (rank : 180)	θ value	0.0252991 (rank : 262)
Query Neighborhood Hits	435	Target Neighborhood Hits	201	Shared Neighborhood Hits	200
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

A20A3_HUMAN
NC score	0.670076 (rank : 181)	θ value	1.69304e-06 (rank : 166)
Query Neighborhood Hits	435	Target Neighborhood Hits	692	Shared Neighborhood Hits	282
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A2_HUMAN
NC score	0.669329 (rank : 182)	θ value	1.69304e-06 (rank : 165)
Query Neighborhood Hits	435	Target Neighborhood Hits	716	Shared Neighborhood Hits	285
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

OSBL1_HUMAN
NC score	0.668227 (rank : 183)	θ value	1.43324e-05 (rank : 189)
Query Neighborhood Hits	435	Target Neighborhood Hits	368	Shared Neighborhood Hits	278
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

ANR38_MOUSE
NC score	0.667957 (rank : 184)	θ value	0.000270298 (rank : 222)
Query Neighborhood Hits	435	Target Neighborhood Hits	512	Shared Neighborhood Hits	239
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

A20A1_HUMAN
NC score	0.667405 (rank : 185)	θ value	4.92598e-06 (rank : 180)
Query Neighborhood Hits	435	Target Neighborhood Hits	698	Shared Neighborhood Hits	279
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A4_HUMAN
NC score	0.665289 (rank : 186)	θ value	1.69304e-06 (rank : 167)
Query Neighborhood Hits	435	Target Neighborhood Hits	710	Shared Neighborhood Hits	282
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

KRIT1_HUMAN
NC score	0.659703 (rank : 187)	θ value	0.0193708 (rank : 259)
Query Neighborhood Hits	435	Target Neighborhood Hits	258	Shared Neighborhood Hits	223
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

RAI14_HUMAN
NC score	0.657671 (rank : 188)	θ value	1.29331e-14 (rank : 46)
Query Neighborhood Hits	435	Target Neighborhood Hits	1367	Shared Neighborhood Hits	312
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

OSBL1_MOUSE
NC score	0.655466 (rank : 189)	θ value	1.43324e-05 (rank : 190)
Query Neighborhood Hits	435	Target Neighborhood Hits	336	Shared Neighborhood Hits	279
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSTF1_MOUSE
NC score	0.655234 (rank : 190)	θ value	0.000158464 (rank : 218)
Query Neighborhood Hits	435	Target Neighborhood Hits	467	Shared Neighborhood Hits	258
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

CLPB_HUMAN
NC score	0.648229 (rank : 191)	θ value	1.87187e-05 (rank : 193)
Query Neighborhood Hits	435	Target Neighborhood Hits	265	Shared Neighborhood Hits	236
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

CD2A1_HUMAN
NC score	0.647946 (rank : 192)	θ value	0.000602161 (rank : 230)
Query Neighborhood Hits	435	Target Neighborhood Hits	196	Shared Neighborhood Hits	194
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

OSTF1_HUMAN
NC score	0.639025 (rank : 193)	θ value	0.000158464 (rank : 217)
Query Neighborhood Hits	435	Target Neighborhood Hits	466	Shared Neighborhood Hits	257
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ANR40_HUMAN
NC score	0.638024 (rank : 194)	θ value	5.44631e-05 (rank : 203)
Query Neighborhood Hits	435	Target Neighborhood Hits	224	Shared Neighborhood Hits	202
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
NC score	0.635116 (rank : 195)	θ value	7.1131e-05 (rank : 204)
Query Neighborhood Hits	435	Target Neighborhood Hits	228	Shared Neighborhood Hits	206
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

CDN2B_HUMAN
NC score	0.629124 (rank : 196)	θ value	1.38821 (rank : 333)
Query Neighborhood Hits	435	Target Neighborhood Hits	196	Shared Neighborhood Hits	194
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

ABTB2_HUMAN
NC score	0.628194 (rank : 197)	θ value	1.63604e-09 (rank : 110)
Query Neighborhood Hits	435	Target Neighborhood Hits	391	Shared Neighborhood Hits	240
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

RAI14_MOUSE
NC score	0.623737 (rank : 198)	θ value	2.88119e-14 (rank : 48)
Query Neighborhood Hits	435	Target Neighborhood Hits	1505	Shared Neighborhood Hits	313
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

HECD1_HUMAN
NC score	0.621138 (rank : 199)	θ value	9.92553e-07 (rank : 160)
Query Neighborhood Hits	435	Target Neighborhood Hits	371	Shared Neighborhood Hits	268
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ABTB2_MOUSE
NC score	0.616584 (rank : 200)	θ value	2.36244e-08 (rank : 131)
Query Neighborhood Hits	435	Target Neighborhood Hits	414	Shared Neighborhood Hits	241
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR18_HUMAN
NC score	0.616217 (rank : 201)	θ value	5.44631e-05 (rank : 202)
Query Neighborhood Hits	435	Target Neighborhood Hits	1106	Shared Neighborhood Hits	280
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR45_MOUSE
NC score	0.615305 (rank : 202)	θ value	0.163984 (rank : 288)
Query Neighborhood Hits	435	Target Neighborhood Hits	204	Shared Neighborhood Hits	188
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR43_HUMAN
NC score	0.614799 (rank : 203)	θ value	0.0193708 (rank : 256)
Query Neighborhood Hits	435	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

NUD12_MOUSE
NC score	0.614094 (rank : 204)	θ value	1.87187e-05 (rank : 195)
Query Neighborhood Hits	435	Target Neighborhood Hits	243	Shared Neighborhood Hits	222
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ANR43_MOUSE
NC score	0.608824 (rank : 205)	θ value	0.0431538 (rank : 271)
Query Neighborhood Hits	435	Target Neighborhood Hits	214	Shared Neighborhood Hits	206
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

TRPV6_MOUSE
NC score	0.596372 (rank : 206)	θ value	1.69304e-06 (rank : 169)
Query Neighborhood Hits	435	Target Neighborhood Hits	284	Shared Neighborhood Hits	255
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

AN30A_HUMAN
NC score	0.595455 (rank : 207)	θ value	7.34386e-10 (rank : 100)
Query Neighborhood Hits	435	Target Neighborhood Hits	1119	Shared Neighborhood Hits	288
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANKY1_HUMAN
NC score	0.591886 (rank : 208)	θ value	0.00134147 (rank : 235)
Query Neighborhood Hits	435	Target Neighborhood Hits	248	Shared Neighborhood Hits	203
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ANR45_HUMAN
NC score	0.590814 (rank : 209)	θ value	0.00134147 (rank : 237)
Query Neighborhood Hits	435	Target Neighborhood Hits	201	Shared Neighborhood Hits	183
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

IASPP_HUMAN
NC score	0.586655 (rank : 210)	θ value	1.87187e-05 (rank : 194)
Query Neighborhood Hits	435	Target Neighborhood Hits	688	Shared Neighborhood Hits	277
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ASPP2_HUMAN
NC score	0.585545 (rank : 211)	θ value	8.40245e-06 (rank : 185)
Query Neighborhood Hits	435	Target Neighborhood Hits	1156	Shared Neighborhood Hits	298
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ANKK1_HUMAN
NC score	0.584208 (rank : 212)	θ value	1.57365e-28 (rank : 7)
Query Neighborhood Hits	435	Target Neighborhood Hits	1075	Shared Neighborhood Hits	295
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

NUD12_HUMAN
NC score	0.582532 (rank : 213)	θ value	0.000121331 (rank : 215)
Query Neighborhood Hits	435	Target Neighborhood Hits	222	Shared Neighborhood Hits	202
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ASPP1_HUMAN
NC score	0.568516 (rank : 214)	θ value	7.1131e-05 (rank : 208)
Query Neighborhood Hits	435	Target Neighborhood Hits	956	Shared Neighborhood Hits	283
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

RIPK4_HUMAN
NC score	0.568506 (rank : 215)	θ value	1.13037e-18 (rank : 21)
Query Neighborhood Hits	435	Target Neighborhood Hits	1094	Shared Neighborhood Hits	301
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

ANKK1_MOUSE
NC score	0.566865 (rank : 216)	θ value	6.84181e-24 (rank : 9)
Query Neighborhood Hits	435	Target Neighborhood Hits	1072	Shared Neighborhood Hits	291
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ASB14_HUMAN
NC score	0.556247 (rank : 217)	θ value	0.0252991 (rank : 261)
Query Neighborhood Hits	435	Target Neighborhood Hits	187	Shared Neighborhood Hits	175
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CENB1_HUMAN
NC score	0.554524 (rank : 218)	θ value	6.43352e-06 (rank : 184)
Query Neighborhood Hits	435	Target Neighborhood Hits	383	Shared Neighborhood Hits	258
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB5_HUMAN
NC score	0.554396 (rank : 219)	θ value	0.00020696 (rank : 220)
Query Neighborhood Hits	435	Target Neighborhood Hits	395	Shared Neighborhood Hits	262
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

ASPP1_MOUSE
NC score	0.551534 (rank : 220)	θ value	7.1131e-05 (rank : 209)
Query Neighborhood Hits	435	Target Neighborhood Hits	1244	Shared Neighborhood Hits	297
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

TRPV5_MOUSE
NC score	0.546547 (rank : 221)	θ value	1.29631e-06 (rank : 164)
Query Neighborhood Hits	435	Target Neighborhood Hits	278	Shared Neighborhood Hits	247
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

CENB2_HUMAN
NC score	0.545738 (rank : 222)	θ value	1.09739e-05 (rank : 186)
Query Neighborhood Hits	435	Target Neighborhood Hits	425	Shared Neighborhood Hits	255
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

AN13B_MOUSE
NC score	0.532328 (rank : 223)	θ value	0.00665767 (rank : 245)
Query Neighborhood Hits	435	Target Neighborhood Hits	276	Shared Neighborhood Hits	253
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

IASPP_MOUSE
NC score	0.531951 (rank : 224)	θ value	9.92553e-07 (rank : 161)
Query Neighborhood Hits	435	Target Neighborhood Hits	1024	Shared Neighborhood Hits	280
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

AN13B_HUMAN
NC score	0.531541 (rank : 225)	θ value	0.00665767 (rank : 244)
Query Neighborhood Hits	435	Target Neighborhood Hits	265	Shared Neighborhood Hits	252
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ILK2_HUMAN
NC score	0.523976 (rank : 226)	θ value	2.21117e-06 (rank : 174)
Query Neighborhood Hits	435	Target Neighborhood Hits	848	Shared Neighborhood Hits	283
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

UACA_HUMAN
NC score	0.519839 (rank : 227)	θ value	4.30538e-10 (rank : 96)
Query Neighborhood Hits	435	Target Neighborhood Hits	1622	Shared Neighborhood Hits	304
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

TRPV5_HUMAN
NC score	0.514002 (rank : 228)	θ value	7.59969e-07 (rank : 157)
Query Neighborhood Hits	435	Target Neighborhood Hits	261	Shared Neighborhood Hits	226
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

AN13C_HUMAN
NC score	0.511790 (rank : 229)	θ value	0.163984 (rank : 287)
Query Neighborhood Hits	435	Target Neighborhood Hits	241	Shared Neighborhood Hits	233
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

GIT2_MOUSE
NC score	0.507741 (rank : 230)	θ value	0.0431538 (rank : 272)
Query Neighborhood Hits	435	Target Neighborhood Hits	323	Shared Neighborhood Hits	251
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

GLSL_HUMAN
NC score	0.506436 (rank : 231)	θ value	1.38821 (rank : 335)
Query Neighborhood Hits	435	Target Neighborhood Hits	211	Shared Neighborhood Hits	201
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

ILK1_HUMAN
NC score	0.506349 (rank : 232)	θ value	2.21117e-06 (rank : 173)
Query Neighborhood Hits	435	Target Neighborhood Hits	857	Shared Neighborhood Hits	283
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

TRPV6_HUMAN
NC score	0.505651 (rank : 233)	θ value	0.000121331 (rank : 216)
Query Neighborhood Hits	435	Target Neighborhood Hits	262	Shared Neighborhood Hits	228
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

CT012_MOUSE
NC score	0.505108 (rank : 234)	θ value	7.1131e-05 (rank : 210)
Query Neighborhood Hits	435	Target Neighborhood Hits	229	Shared Neighborhood Hits	182
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

ILK_MOUSE
NC score	0.503876 (rank : 235)	θ value	4.92598e-06 (rank : 181)
Query Neighborhood Hits	435	Target Neighborhood Hits	858	Shared Neighborhood Hits	283
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

AN13C_MOUSE
NC score	0.500144 (rank : 236)	θ value	0.279714 (rank : 301)
Query Neighborhood Hits	435	Target Neighborhood Hits	242	Shared Neighborhood Hits	229
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

UACA_MOUSE
NC score	0.494407 (rank : 237)	θ value	1.47974e-10 (rank : 85)
Query Neighborhood Hits	435	Target Neighborhood Hits	1620	Shared Neighborhood Hits	303
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

GLSL_MOUSE
NC score	0.493695 (rank : 238)	θ value	3.0926 (rank : 366)
Query Neighborhood Hits	435	Target Neighborhood Hits	212	Shared Neighborhood Hits	202
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GIT1_MOUSE
NC score	0.489357 (rank : 239)	θ value	0.125558 (rank : 285)
Query Neighborhood Hits	435	Target Neighborhood Hits	341	Shared Neighborhood Hits	248
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT1_HUMAN
NC score	0.488137 (rank : 240)	θ value	0.125558 (rank : 284)
Query Neighborhood Hits	435	Target Neighborhood Hits	336	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

AN13A_HUMAN
NC score	0.476058 (rank : 241)	θ value	0.000602161 (rank : 227)
Query Neighborhood Hits	435	Target Neighborhood Hits	243	Shared Neighborhood Hits	224
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ANR26_MOUSE
NC score	0.468907 (rank : 242)	θ value	1.99992e-07 (rank : 151)
Query Neighborhood Hits	435	Target Neighborhood Hits	1554	Shared Neighborhood Hits	300
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GIT2_HUMAN
NC score	0.467102 (rank : 243)	θ value	0.163984 (rank : 293)
Query Neighborhood Hits	435	Target Neighborhood Hits	381	Shared Neighborhood Hits	245
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

CT012_HUMAN
NC score	0.463970 (rank : 244)	θ value	0.00020696 (rank : 221)
Query Neighborhood Hits	435	Target Neighborhood Hits	205	Shared Neighborhood Hits	167
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

NOTC4_MOUSE
NC score	0.461207 (rank : 245)	θ value	8.97725e-08 (rank : 147)
Query Neighborhood Hits	435	Target Neighborhood Hits	872	Shared Neighborhood Hits	286
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

GLSK_HUMAN
NC score	0.459448 (rank : 246)	θ value	6.88961 (rank : 404)
Query Neighborhood Hits	435	Target Neighborhood Hits	204	Shared Neighborhood Hits	190
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

TNI3K_HUMAN
NC score	0.457273 (rank : 247)	θ value	1.5773e-20 (rank : 15)
Query Neighborhood Hits	435	Target Neighborhood Hits	1084	Shared Neighborhood Hits	297
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

NOTC4_HUMAN
NC score	0.455594 (rank : 248)	θ value	4.0297e-08 (rank : 140)
Query Neighborhood Hits	435	Target Neighborhood Hits	905	Shared Neighborhood Hits	289
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

DDFL1_MOUSE
NC score	0.453688 (rank : 249)	θ value	0.0113563 (rank : 248)
Query Neighborhood Hits	435	Target Neighborhood Hits	324	Shared Neighborhood Hits	249
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

TNI3K_MOUSE
NC score	0.451844 (rank : 250)	θ value	8.65492e-19 (rank : 19)
Query Neighborhood Hits	435	Target Neighborhood Hits	1079	Shared Neighborhood Hits	296
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

AN13A_MOUSE
NC score	0.449534 (rank : 251)	θ value	0.00298849 (rank : 240)
Query Neighborhood Hits	435	Target Neighborhood Hits	226	Shared Neighborhood Hits	214
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

ANR26_HUMAN
NC score	0.446880 (rank : 252)	θ value	2.21117e-06 (rank : 170)
Query Neighborhood Hits	435	Target Neighborhood Hits	1614	Shared Neighborhood Hits	304
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NOTC3_MOUSE
NC score	0.421490 (rank : 253)	θ value	5.26297e-08 (rank : 142)
Query Neighborhood Hits	435	Target Neighborhood Hits	975	Shared Neighborhood Hits	300
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TEX14_MOUSE
NC score	0.419351 (rank : 254)	θ value	1.06045e-08 (rank : 123)
Query Neighborhood Hits	435	Target Neighborhood Hits	1333	Shared Neighborhood Hits	265
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

NOTC3_HUMAN
NC score	0.419105 (rank : 255)	θ value	4.0297e-08 (rank : 139)
Query Neighborhood Hits	435	Target Neighborhood Hits	1062	Shared Neighborhood Hits	298
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_HUMAN
NC score	0.416371 (rank : 256)	θ value	2.61198e-07 (rank : 153)
Query Neighborhood Hits	435	Target Neighborhood Hits	906	Shared Neighborhood Hits	288
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
NC score	0.415921 (rank : 257)	θ value	4.76016e-09 (rank : 118)
Query Neighborhood Hits	435	Target Neighborhood Hits	1113	Shared Neighborhood Hits	302
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
NC score	0.413429 (rank : 258)	θ value	2.13673e-09 (rank : 112)
Query Neighborhood Hits	435	Target Neighborhood Hits	1069	Shared Neighborhood Hits	298
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TEX14_HUMAN
NC score	0.410965 (rank : 259)	θ value	3.19293e-05 (rank : 199)
Query Neighborhood Hits	435	Target Neighborhood Hits	1103	Shared Neighborhood Hits	255
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DAPK1_MOUSE
NC score	0.410723 (rank : 260)	θ value	3.39556e-23 (rank : 11)
Query Neighborhood Hits	435	Target Neighborhood Hits	1138	Shared Neighborhood Hits	295
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK1_HUMAN
NC score	0.401130 (rank : 261)	θ value	4.15078e-21 (rank : 14)
Query Neighborhood Hits	435	Target Neighborhood Hits	1130	Shared Neighborhood Hits	291
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DGKZ_HUMAN
NC score	0.369025 (rank : 262)	θ value	4.03905 (rank : 376)
Query Neighborhood Hits	435	Target Neighborhood Hits	551	Shared Neighborhood Hits	219
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DDEF2_HUMAN
NC score	0.366176 (rank : 263)	θ value	6.88961 (rank : 399)
Query Neighborhood Hits	435	Target Neighborhood Hits	599	Shared Neighborhood Hits	245
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.365439 (rank : 264)	θ value	6.88961 (rank : 400)
Query Neighborhood Hits	435	Target Neighborhood Hits	625	Shared Neighborhood Hits	254
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ANKZ1_MOUSE
NC score	0.363837 (rank : 265)	θ value	0.0330416 (rank : 265)
Query Neighborhood Hits	435	Target Neighborhood Hits	208	Shared Neighborhood Hits	151
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

ANKZ1_HUMAN
NC score	0.358555 (rank : 266)	θ value	0.00509761 (rank : 242)
Query Neighborhood Hits	435	Target Neighborhood Hits	236	Shared Neighborhood Hits	157
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

DDFL1_HUMAN
NC score	0.354891 (rank : 267)	θ value	0.47712 (rank : 311)
Query Neighborhood Hits	435	Target Neighborhood Hits	353	Shared Neighborhood Hits	232
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

CENG2_HUMAN
NC score	0.354160 (rank : 268)	θ value	0.0193708 (rank : 258)
Query Neighborhood Hits	435	Target Neighborhood Hits	471	Shared Neighborhood Hits	252
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

NOTC1_MOUSE
NC score	0.353098 (rank : 269)	θ value	0.000786445 (rank : 234)
Query Neighborhood Hits	435	Target Neighborhood Hits	916	Shared Neighborhood Hits	265
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DGKI_HUMAN
NC score	0.352518 (rank : 270)	θ value	0.0113563 (rank : 249)
Query Neighborhood Hits	435	Target Neighborhood Hits	609	Shared Neighborhood Hits	218
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

CENG2_MOUSE
NC score	0.351373 (rank : 271)	θ value	0.0148317 (rank : 252)
Query Neighborhood Hits	435	Target Neighborhood Hits	463	Shared Neighborhood Hits	249
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENG1_MOUSE
NC score	0.350724 (rank : 272)	θ value	0.125558 (rank : 283)
Query Neighborhood Hits	435	Target Neighborhood Hits	531	Shared Neighborhood Hits	253
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG1_HUMAN
NC score	0.347842 (rank : 273)	θ value	0.125558 (rank : 282)
Query Neighborhood Hits	435	Target Neighborhood Hits	544	Shared Neighborhood Hits	254
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

DGKZ_MOUSE
NC score	0.343437 (rank : 274)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	435	Target Neighborhood Hits	542	Shared Neighborhood Hits	205
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

CENG3_MOUSE
NC score	0.317310 (rank : 275)	θ value	0.163984 (rank : 291)
Query Neighborhood Hits	435	Target Neighborhood Hits	467	Shared Neighborhood Hits	230
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_HUMAN
NC score	0.316706 (rank : 276)	θ value	0.163984 (rank : 290)
Query Neighborhood Hits	435	Target Neighborhood Hits	455	Shared Neighborhood Hits	228
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

BAT4_MOUSE
NC score	0.313457 (rank : 277)	θ value	0.163984 (rank : 289)
Query Neighborhood Hits	435	Target Neighborhood Hits	171	Shared Neighborhood Hits	123
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

ABTB1_MOUSE
NC score	0.307742 (rank : 278)	θ value	3.0926 (rank : 361)
Query Neighborhood Hits	435	Target Neighborhood Hits	349	Shared Neighborhood Hits	176
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

IKBL_HUMAN
NC score	0.304794 (rank : 279)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	435	Target Neighborhood Hits	168	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
NC score	0.297659 (rank : 280)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	435	Target Neighborhood Hits	196	Shared Neighborhood Hits	138
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

BAT4_HUMAN
NC score	0.289531 (rank : 281)	θ value	0.0736092 (rank : 277)
Query Neighborhood Hits	435	Target Neighborhood Hits	157	Shared Neighborhood Hits	110
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CLR59_HUMAN
NC score	0.282080 (rank : 282)	θ value	1.38821 (rank : 334)
Query Neighborhood Hits	435	Target Neighborhood Hits	163	Shared Neighborhood Hits	140
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

TRPV3_MOUSE
NC score	0.275909 (rank : 283)	θ value	0.0431538 (rank : 273)
Query Neighborhood Hits	435	Target Neighborhood Hits	188	Shared Neighborhood Hits	135
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV3_HUMAN
NC score	0.275731 (rank : 284)	θ value	0.125558 (rank : 286)
Query Neighborhood Hits	435	Target Neighborhood Hits	198	Shared Neighborhood Hits	146
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV1_MOUSE
NC score	0.274847 (rank : 285)	θ value	0.163984 (rank : 296)
Query Neighborhood Hits	435	Target Neighborhood Hits	189	Shared Neighborhood Hits	157
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

DDEF1_MOUSE
NC score	0.269623 (rank : 286)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	435	Target Neighborhood Hits	592	Shared Neighborhood Hits	204
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

ABTB1_HUMAN
NC score	0.264616 (rank : 287)	θ value	8.99809 (rank : 414)
Query Neighborhood Hits	435	Target Neighborhood Hits	325	Shared Neighborhood Hits	162
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ANKR9_MOUSE
NC score	0.260045 (rank : 288)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	435	Target Neighborhood Hits	120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

TRPV1_HUMAN
NC score	0.257594 (rank : 289)	θ value	0.47712 (rank : 315)
Query Neighborhood Hits	435	Target Neighborhood Hits	184	Shared Neighborhood Hits	149
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV2_HUMAN
NC score	0.227402 (rank : 290)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	435	Target Neighborhood Hits	130	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

RSNL2_HUMAN
NC score	0.217698 (rank : 291)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	435	Target Neighborhood Hits	136	Shared Neighborhood Hits	112
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

ANKR9_HUMAN
NC score	0.211942 (rank : 292)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	435	Target Neighborhood Hits	99	Shared Neighborhood Hits	96
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

CMTA1_HUMAN
NC score	0.197494 (rank : 293)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	435	Target Neighborhood Hits	217	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

TRPV2_MOUSE
NC score	0.183988 (rank : 294)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	435	Target Neighborhood Hits	111	Shared Neighborhood Hits	93
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

RSNL2_MOUSE
NC score	0.183300 (rank : 295)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	435	Target Neighborhood Hits	129	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

CMTA2_HUMAN
NC score	0.174168 (rank : 296)	θ value	0.365318 (rank : 307)
Query Neighborhood Hits	435	Target Neighborhood Hits	199	Shared Neighborhood Hits	98
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TRPV4_HUMAN
NC score	0.167911 (rank : 297)	θ value	0.0330416 (rank : 270)
Query Neighborhood Hits	435	Target Neighborhood Hits	150	Shared Neighborhood Hits	86
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

CMTA2_MOUSE
NC score	0.161866 (rank : 298)	θ value	0.365318 (rank : 308)
Query Neighborhood Hits	435	Target Neighborhood Hits	216	Shared Neighborhood Hits	87
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TRPV4_MOUSE
NC score	0.157426 (rank : 299)	θ value	0.0431538 (rank : 274)
Query Neighborhood Hits	435	Target Neighborhood Hits	117	Shared Neighborhood Hits	81
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

ANKF1_HUMAN
NC score	0.136257 (rank : 300)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	435	Target Neighborhood Hits	126	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

TRPC6_HUMAN
NC score	0.126465 (rank : 301)	θ value	0.365318 (rank : 310)
Query Neighborhood Hits	435	Target Neighborhood Hits	171	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC3_HUMAN
NC score	0.104052 (rank : 302)	θ value	0.47712 (rank : 313)
Query Neighborhood Hits	435	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

S23IP_MOUSE
NC score	0.102135 (rank : 303)	θ value	0.000461057 (rank : 226)
Query Neighborhood Hits	435	Target Neighborhood Hits	363	Shared Neighborhood Hits	48
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

LRRK1_MOUSE
NC score	0.101703 (rank : 304)	θ value	0.0113563 (rank : 250)
Query Neighborhood Hits	435	Target Neighborhood Hits	1267	Shared Neighborhood Hits	128
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

TRPC6_MOUSE
NC score	0.098588 (rank : 305)	θ value	0.47712 (rank : 314)
Query Neighborhood Hits	435	Target Neighborhood Hits	171	Shared Neighborhood Hits	94
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC3_MOUSE
NC score	0.096823 (rank : 306)	θ value	1.81305 (rank : 346)
Query Neighborhood Hits	435	Target Neighborhood Hits	131	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

CU081_HUMAN
NC score	0.092290 (rank : 307)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	435	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

TRPC7_MOUSE
NC score	0.090512 (rank : 308)	θ value	3.0926 (rank : 371)
Query Neighborhood Hits	435	Target Neighborhood Hits	114	Shared Neighborhood Hits	77
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.090242 (rank : 309)	θ value	2.36792 (rank : 359)
Query Neighborhood Hits	435	Target Neighborhood Hits	123	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

S23IP_HUMAN
NC score	0.087583 (rank : 310)	θ value	0.0193708 (rank : 260)
Query Neighborhood Hits	435	Target Neighborhood Hits	134	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6Y8, Q8IXH5, Q9BUK5	Gene names	SEC23IP
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein (p125).

SARM1_MOUSE
NC score	0.085703 (rank : 311)	θ value	0.0330416 (rank : 269)
Query Neighborhood Hits	435	Target Neighborhood Hits	54	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

TRPC5_MOUSE
NC score	0.083089 (rank : 312)	θ value	6.88961 (rank : 413)
Query Neighborhood Hits	435	Target Neighborhood Hits	124	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

SARM1_HUMAN
NC score	0.081895 (rank : 313)	θ value	0.0330416 (rank : 268)
Query Neighborhood Hits	435	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

TRPC5_HUMAN
NC score	0.081743 (rank : 314)	θ value	6.88961 (rank : 412)
Query Neighborhood Hits	435	Target Neighborhood Hits	122	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

LRRK1_HUMAN
NC score	0.079323 (rank : 315)	θ value	0.0148317 (rank : 253)
Query Neighborhood Hits	435	Target Neighborhood Hits	1237	Shared Neighborhood Hits	102
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

SAM14_MOUSE
NC score	0.077506 (rank : 316)	θ value	0.163984 (rank : 294)
Query Neighborhood Hits	435	Target Neighborhood Hits	91	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K070, Q5SWB7, Q8BHE2, Q8C8N5	Gene names	Samd14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

TRPC4_MOUSE
NC score	0.073007 (rank : 317)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	435	Target Neighborhood Hits	141	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC4_HUMAN
NC score	0.072913 (rank : 318)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	435	Target Neighborhood Hits	140	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

ZCH14_HUMAN
NC score	0.071120 (rank : 319)	θ value	0.00869519 (rank : 247)
Query Neighborhood Hits	435	Target Neighborhood Hits	117	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

SAM14_HUMAN
NC score	0.070999 (rank : 320)	θ value	0.62314 (rank : 320)
Query Neighborhood Hits	435	Target Neighborhood Hits	81	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

ZCH14_MOUSE
NC score	0.068011 (rank : 321)	θ value	0.0252991 (rank : 264)
Query Neighborhood Hits	435	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

LRSM1_HUMAN
NC score	0.062190 (rank : 322)	θ value	0.000786445 (rank : 233)
Query Neighborhood Hits	435	Target Neighborhood Hits	1078	Shared Neighborhood Hits	46
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

SRRM2_HUMAN
NC score	0.061756 (rank : 323)	θ value	1.81305 (rank : 345)
Query Neighborhood Hits	435	Target Neighborhood Hits	1296	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

DGKD_HUMAN
NC score	0.058813 (rank : 324)	θ value	0.0736092 (rank : 278)
Query Neighborhood Hits	435	Target Neighborhood Hits	231	Shared Neighborhood Hits	35
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

OGFR_HUMAN
NC score	0.058740 (rank : 325)	θ value	0.00175202 (rank : 238)
Query Neighborhood Hits	435	Target Neighborhood Hits	1582	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

FADD_MOUSE
NC score	0.058662 (rank : 326)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	435	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

LRSM1_MOUSE
NC score	0.057628 (rank : 327)	θ value	0.0148317 (rank : 254)
Query Neighborhood Hits	435	Target Neighborhood Hits	874	Shared Neighborhood Hits	37
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

WASIP_MOUSE
NC score	0.055111 (rank : 328)	θ value	0.279714 (rank : 306)
Query Neighborhood Hits	435	Target Neighborhood Hits	392	Shared Neighborhood Hits	52
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

SRRM1_MOUSE
NC score	0.054852 (rank : 329)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	435	Target Neighborhood Hits	966	Shared Neighborhood Hits	80
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

CNKR2_HUMAN
NC score	0.054786 (rank : 330)	θ value	0.279714 (rank : 303)
Query Neighborhood Hits	435	Target Neighborhood Hits	197	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

EVL_HUMAN
NC score	0.054720 (rank : 331)	θ value	0.0252991 (rank : 263)
Query Neighborhood Hits	435	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

CNKR2_MOUSE
NC score	0.054664 (rank : 332)	θ value	0.279714 (rank : 304)
Query Neighborhood Hits	435	Target Neighborhood Hits	197	Shared Neighborhood Hits	25
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

TRPC1_HUMAN
NC score	0.054487 (rank : 333)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	435	Target Neighborhood Hits	91	Shared Neighborhood Hits	55
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

FADD_HUMAN
NC score	0.053604 (rank : 334)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	435	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q13158, Q14866	Gene names	FADD, MORT1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

SSB4_HUMAN
NC score	0.052697 (rank : 335)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	435	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

SRRM1_HUMAN
NC score	0.052416 (rank : 336)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	435	Target Neighborhood Hits	690	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

WASIP_HUMAN
NC score	0.052339 (rank : 337)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	435	Target Neighborhood Hits	458	Shared Neighborhood Hits	57
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

TRDN_HUMAN
NC score	0.051311 (rank : 338)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	435	Target Neighborhood Hits	542	Shared Neighborhood Hits	32
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

BASP_MOUSE
NC score	0.051119 (rank : 339)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	435	Target Neighborhood Hits	260	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SPSB2_MOUSE
NC score	0.051042 (rank : 340)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	435	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	O88838, Q8CBA5, Q91Z15	Gene names	Spsb2, Grcc9, Ssb2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

BSN_MOUSE
NC score	0.049734 (rank : 341)	θ value	0.62314 (rank : 316)
Query Neighborhood Hits	435	Target Neighborhood Hits	2057	Shared Neighborhood Hits	133
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SRRM2_MOUSE
NC score	0.048757 (rank : 342)	θ value	5.27518 (rank : 395)
Query Neighborhood Hits	435	Target Neighborhood Hits	1470	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SHAN2_HUMAN
NC score	0.048253 (rank : 343)	θ value	8.99809 (rank : 433)
Query Neighborhood Hits	435	Target Neighborhood Hits	346	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
NC score	0.047811 (rank : 344)	θ value	8.99809 (rank : 434)
Query Neighborhood Hits	435	Target Neighborhood Hits	446	Shared Neighborhood Hits	48
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

NACAM_MOUSE
NC score	0.047488 (rank : 345)	θ value	1.38821 (rank : 337)
Query Neighborhood Hits	435	Target Neighborhood Hits	1866	Shared Neighborhood Hits	111
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TGON2_HUMAN
NC score	0.045898 (rank : 346)	θ value	0.163984 (rank : 295)
Query Neighborhood Hits	435	Target Neighborhood Hits	1037	Shared Neighborhood Hits	75
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

GON4L_MOUSE
NC score	0.045655 (rank : 347)	θ value	0.0736092 (rank : 279)
Query Neighborhood Hits	435	Target Neighborhood Hits	455	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

EVL_MOUSE
NC score	0.045559 (rank : 348)	θ value	0.0330416 (rank : 266)
Query Neighborhood Hits	435	Target Neighborhood Hits	203	Shared Neighborhood Hits	25
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

GRIN1_HUMAN
NC score	0.044745 (rank : 349)	θ value	4.03905 (rank : 378)
Query Neighborhood Hits	435	Target Neighborhood Hits	681	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

DGKH_HUMAN
NC score	0.044413 (rank : 350)	θ value	1.06291 (rank : 328)
Query Neighborhood Hits	435	Target Neighborhood Hits	255	Shared Neighborhood Hits	33
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

FBX41_HUMAN
NC score	0.042128 (rank : 351)	θ value	0.000461057 (rank : 224)
Query Neighborhood Hits	435	Target Neighborhood Hits	475	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

MUCDL_HUMAN
NC score	0.042074 (rank : 352)	θ value	1.06291 (rank : 332)
Query Neighborhood Hits	435	Target Neighborhood Hits	777	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PI5PA_HUMAN
NC score	0.040603 (rank : 353)	θ value	0.62314 (rank : 318)
Query Neighborhood Hits	435	Target Neighborhood Hits	749	Shared Neighborhood Hits	60
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

TPR_HUMAN
NC score	0.040238 (rank : 354)	θ value	0.365318 (rank : 309)
Query Neighborhood Hits	435	Target Neighborhood Hits	1921	Shared Neighborhood Hits	77
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

HRBL_MOUSE
NC score	0.039267 (rank : 355)	θ value	2.36792 (rank : 351)
Query Neighborhood Hits	435	Target Neighborhood Hits	269	Shared Neighborhood Hits	33
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

LIPB2_HUMAN
NC score	0.038908 (rank : 356)	θ value	0.62314 (rank : 317)
Query Neighborhood Hits	435	Target Neighborhood Hits	599	Shared Neighborhood Hits	38
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

NFH_MOUSE
NC score	0.036537 (rank : 357)	θ value	0.0736092 (rank : 280)
Query Neighborhood Hits	435	Target Neighborhood Hits	2247	Shared Neighborhood Hits	113
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

GON4L_HUMAN
NC score	0.035465 (rank : 358)	θ value	1.06291 (rank : 330)
Query Neighborhood Hits	435	Target Neighborhood Hits	555	Shared Neighborhood Hits	40
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

NCOA6_HUMAN
NC score	0.035313 (rank : 359)	θ value	4.03905 (rank : 380)
Query Neighborhood Hits	435	Target Neighborhood Hits	1202	Shared Neighborhood Hits	82
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

GRIN1_MOUSE
NC score	0.034436 (rank : 360)	θ value	0.813845 (rank : 323)
Query Neighborhood Hits	435	Target Neighborhood Hits	337	Shared Neighborhood Hits	40
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

PCLO_MOUSE
NC score	0.032772 (rank : 361)	θ value	5.27518 (rank : 390)
Query Neighborhood Hits	435	Target Neighborhood Hits	2275	Shared Neighborhood Hits	113
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MACOI_MOUSE
NC score	0.032658 (rank : 362)	θ value	6.88961 (rank : 407)
Query Neighborhood Hits	435	Target Neighborhood Hits	620	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

RTP3_MOUSE
NC score	0.031987 (rank : 363)	θ value	3.0926 (rank : 369)
Query Neighborhood Hits	435	Target Neighborhood Hits	374	Shared Neighborhood Hits	36
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

PRR8_HUMAN
NC score	0.031394 (rank : 364)	θ value	6.88961 (rank : 409)
Query Neighborhood Hits	435	Target Neighborhood Hits	217	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

X3CL1_HUMAN
NC score	0.031020 (rank : 365)	θ value	0.62314 (rank : 321)
Query Neighborhood Hits	435	Target Neighborhood Hits	152	Shared Neighborhood Hits	13
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

RGS3_MOUSE
NC score	0.030844 (rank : 366)	θ value	0.47712 (rank : 312)
Query Neighborhood Hits	435	Target Neighborhood Hits	1621	Shared Neighborhood Hits	91
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CD2_HUMAN
NC score	0.029589 (rank : 367)	θ value	0.21417 (rank : 298)
Query Neighborhood Hits	435	Target Neighborhood Hits	504	Shared Neighborhood Hits	33
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

LAD1_HUMAN
NC score	0.028515 (rank : 368)	θ value	8.99809 (rank : 423)
Query Neighborhood Hits	435	Target Neighborhood Hits	441	Shared Neighborhood Hits	38
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

TM108_MOUSE
NC score	0.028250 (rank : 369)	θ value	3.0926 (rank : 370)
Query Neighborhood Hits	435	Target Neighborhood Hits	336	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

LCP2_HUMAN
NC score	0.027982 (rank : 370)	θ value	5.27518 (rank : 388)
Query Neighborhood Hits	435	Target Neighborhood Hits	531	Shared Neighborhood Hits	37
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MEGF9_MOUSE
NC score	0.027975 (rank : 371)	θ value	4.03905 (rank : 379)
Query Neighborhood Hits	435	Target Neighborhood Hits	896	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MAML2_HUMAN
NC score	0.027908 (rank : 372)	θ value	1.81305 (rank : 342)
Query Neighborhood Hits	435	Target Neighborhood Hits	360	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

BRD4_MOUSE
NC score	0.027837 (rank : 373)	θ value	2.36792 (rank : 348)
Query Neighborhood Hits	435	Target Neighborhood Hits	845	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

PI5PA_MOUSE
NC score	0.027542 (rank : 374)	θ value	8.99809 (rank : 432)
Query Neighborhood Hits	435	Target Neighborhood Hits	331	Shared Neighborhood Hits	42
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

LIPA3_MOUSE
NC score	0.027384 (rank : 375)	θ value	8.99809 (rank : 425)
Query Neighborhood Hits	435	Target Neighborhood Hits	636	Shared Neighborhood Hits	46
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

RANB3_HUMAN
NC score	0.027291 (rank : 376)	θ value	3.0926 (rank : 368)
Query Neighborhood Hits	435	Target Neighborhood Hits	117	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

AFF1_MOUSE
NC score	0.027242 (rank : 377)	θ value	3.0926 (rank : 362)
Query Neighborhood Hits	435	Target Neighborhood Hits	351	Shared Neighborhood Hits	43
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

MCPH1_MOUSE
NC score	0.026913 (rank : 378)	θ value	6.88961 (rank : 408)
Query Neighborhood Hits	435	Target Neighborhood Hits	116	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

CBX2_MOUSE
NC score	0.026721 (rank : 379)	θ value	0.21417 (rank : 297)
Query Neighborhood Hits	435	Target Neighborhood Hits	119	Shared Neighborhood Hits	15
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

C1QR1_HUMAN
NC score	0.026390 (rank : 380)	θ value	8.99809 (rank : 415)
Query Neighborhood Hits	435	Target Neighborhood Hits	493	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

TACT_HUMAN
NC score	0.025814 (rank : 381)	θ value	1.38821 (rank : 338)
Query Neighborhood Hits	435	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	P40200	Gene names	CD96
Domain Architecture	No domain graphic available
Description	T-cell surface protein tactile precursor (T cell-activated increased late expression protein) (CD96 antigen).

AKA10_MOUSE
NC score	0.025355 (rank : 382)	θ value	0.0563607 (rank : 275)
Query Neighborhood Hits	435	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	O88845, Q5SUB5, Q5SUB7, Q7TPE7, Q8BQL6	Gene names	Akap10
Domain Architecture	No domain graphic available
Description	A kinase anchor protein 10, mitochondrial precursor (Protein kinase A- anchoring protein 10) (PRKA10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2).

BI2L1_HUMAN
NC score	0.025282 (rank : 383)	θ value	0.279714 (rank : 302)
Query Neighborhood Hits	435	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

BRD8_MOUSE
NC score	0.025254 (rank : 384)	θ value	0.0563607 (rank : 276)
Query Neighborhood Hits	435	Target Neighborhood Hits	422	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

RIN1_MOUSE
NC score	0.024550 (rank : 385)	θ value	0.0736092 (rank : 281)
Query Neighborhood Hits	435	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).

TGON2_MOUSE
NC score	0.023811 (rank : 386)	θ value	4.03905 (rank : 381)
Query Neighborhood Hits	435	Target Neighborhood Hits	277	Shared Neighborhood Hits	19
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

RANB3_MOUSE
NC score	0.023216 (rank : 387)	θ value	0.62314 (rank : 319)
Query Neighborhood Hits	435	Target Neighborhood Hits	123	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

AMOL1_MOUSE
NC score	0.023110 (rank : 388)	θ value	6.88961 (rank : 398)
Query Neighborhood Hits	435	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

JIP1_HUMAN
NC score	0.022511 (rank : 389)	θ value	2.36792 (rank : 352)
Query Neighborhood Hits	435	Target Neighborhood Hits	271	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

IF16_HUMAN
NC score	0.022509 (rank : 390)	θ value	0.813845 (rank : 324)
Query Neighborhood Hits	435	Target Neighborhood Hits	182	Shared Neighborhood Hits	20
SwissProt Accessions	Q16666, Q9UH78	Gene names	IFI16, IFNGIP1
Domain Architecture
Description	Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16).

SRBS1_MOUSE
NC score	0.021768 (rank : 391)	θ value	2.36792 (rank : 356)
Query Neighborhood Hits	435	Target Neighborhood Hits	409	Shared Neighborhood Hits	29
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

K1802_MOUSE
NC score	0.020529 (rank : 392)	θ value	8.99809 (rank : 422)
Query Neighborhood Hits	435	Target Neighborhood Hits	1596	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MRCKB_HUMAN
NC score	0.020298 (rank : 393)	θ value	5.27518 (rank : 389)
Query Neighborhood Hits	435	Target Neighborhood Hits	2239	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SAPS1_HUMAN
NC score	0.020256 (rank : 394)	θ value	2.36792 (rank : 355)
Query Neighborhood Hits	435	Target Neighborhood Hits	704	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

EMSY_HUMAN
NC score	0.019980 (rank : 395)	θ value	1.06291 (rank : 329)
Query Neighborhood Hits	435	Target Neighborhood Hits	296	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

EMSY_MOUSE
NC score	0.019724 (rank : 396)	θ value	3.0926 (rank : 364)
Query Neighborhood Hits	435	Target Neighborhood Hits	294	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

BRD8_HUMAN
NC score	0.019354 (rank : 397)	θ value	4.03905 (rank : 373)
Query Neighborhood Hits	435	Target Neighborhood Hits	292	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

CTND2_HUMAN
NC score	0.019164 (rank : 398)	θ value	1.81305 (rank : 340)
Query Neighborhood Hits	435	Target Neighborhood Hits	333	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

DLG5_HUMAN
NC score	0.018798 (rank : 399)	θ value	6.88961 (rank : 401)
Query Neighborhood Hits	435	Target Neighborhood Hits	1088	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

FILA_HUMAN
NC score	0.017928 (rank : 400)	θ value	6.88961 (rank : 403)
Query Neighborhood Hits	435	Target Neighborhood Hits	685	Shared Neighborhood Hits	32
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

BPA1_MOUSE
NC score	0.017605 (rank : 401)	θ value	1.06291 (rank : 327)
Query Neighborhood Hits	435	Target Neighborhood Hits	1477	Shared Neighborhood Hits	53
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PGCA_HUMAN
NC score	0.017139 (rank : 402)	θ value	8.99809 (rank : 431)
Query Neighborhood Hits	435	Target Neighborhood Hits	821	Shared Neighborhood Hits	50
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

GA2L3_HUMAN
NC score	0.016912 (rank : 403)	θ value	3.0926 (rank : 365)
Query Neighborhood Hits	435	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	Q86XJ1	Gene names	GAS2L3
Domain Architecture	No domain graphic available
Description	GAS2-like protein 3 (Growth arrest-specific 2-like 3).

JHD2B_HUMAN
NC score	0.016295 (rank : 404)	θ value	0.813845 (rank : 325)
Query Neighborhood Hits	435	Target Neighborhood Hits	171	Shared Neighborhood Hits	16
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

KIFC1_HUMAN
NC score	0.015317 (rank : 405)	θ value	0.0330416 (rank : 267)
Query Neighborhood Hits	435	Target Neighborhood Hits	545	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

CJ012_HUMAN
NC score	0.015159 (rank : 406)	θ value	8.99809 (rank : 418)
Query Neighborhood Hits	435	Target Neighborhood Hits	467	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CTND2_MOUSE
NC score	0.014878 (rank : 407)	θ value	3.0926 (rank : 363)
Query Neighborhood Hits	435	Target Neighborhood Hits	227	Shared Neighborhood Hits	20
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

IRX5_MOUSE
NC score	0.014746 (rank : 408)	θ value	0.21417 (rank : 299)
Query Neighborhood Hits	435	Target Neighborhood Hits	324	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

WDR46_MOUSE
NC score	0.014199 (rank : 409)	θ value	4.03905 (rank : 383)
Query Neighborhood Hits	435	Target Neighborhood Hits	243	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

PDXL2_MOUSE
NC score	0.014112 (rank : 410)	θ value	5.27518 (rank : 391)
Query Neighborhood Hits	435	Target Neighborhood Hits	213	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

MYLK_MOUSE
NC score	0.013979 (rank : 411)	θ value	8.99809 (rank : 426)
Query Neighborhood Hits	435	Target Neighborhood Hits	1489	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

LMBL3_HUMAN
NC score	0.013198 (rank : 412)	θ value	2.36792 (rank : 353)
Query Neighborhood Hits	435	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q96JM7, Q5VUM9, Q6P9B5	Gene names	L3MBTL3, KIAA1798
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein) (H-l(3)mbt-like protein).

LCP2_MOUSE
NC score	0.013178 (rank : 413)	θ value	8.99809 (rank : 424)
Query Neighborhood Hits	435	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

NFAC1_HUMAN
NC score	0.012974 (rank : 414)	θ value	8.99809 (rank : 427)
Query Neighborhood Hits	435	Target Neighborhood Hits	312	Shared Neighborhood Hits	34
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

ASXL1_MOUSE
NC score	0.012784 (rank : 415)	θ value	4.03905 (rank : 372)
Query Neighborhood Hits	435	Target Neighborhood Hits	182	Shared Neighborhood Hits	22
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

IQEC3_MOUSE
NC score	0.012741 (rank : 416)	θ value	6.88961 (rank : 406)
Query Neighborhood Hits	435	Target Neighborhood Hits	274	Shared Neighborhood Hits	29
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

JHD2B_MOUSE
NC score	0.012299 (rank : 417)	θ value	1.38821 (rank : 336)
Query Neighborhood Hits	435	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

GA2L2_HUMAN
NC score	0.012018 (rank : 418)	θ value	5.27518 (rank : 387)
Query Neighborhood Hits	435	Target Neighborhood Hits	175	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

TENS1_HUMAN
NC score	0.011734 (rank : 419)	θ value	5.27518 (rank : 396)
Query Neighborhood Hits	435	Target Neighborhood Hits	400	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

SSBP4_HUMAN
NC score	0.011454 (rank : 420)	θ value	2.36792 (rank : 358)
Query Neighborhood Hits	435	Target Neighborhood Hits	753	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SPEG_MOUSE
NC score	0.010763 (rank : 421)	θ value	5.27518 (rank : 394)
Query Neighborhood Hits	435	Target Neighborhood Hits	1959	Shared Neighborhood Hits	81
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZRF1_HUMAN
NC score	0.010679 (rank : 422)	θ value	4.03905 (rank : 385)
Query Neighborhood Hits	435	Target Neighborhood Hits	457	Shared Neighborhood Hits	15
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

APLP1_MOUSE
NC score	0.010458 (rank : 423)	θ value	0.813845 (rank : 322)
Query Neighborhood Hits	435	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	Q03157, Q8VC38	Gene names	Aplp1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

EFNB2_HUMAN
NC score	0.010272 (rank : 424)	θ value	1.81305 (rank : 341)
Query Neighborhood Hits	435	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P52799	Gene names	EFNB2, EPLG5, HTKL, LERK5
Domain Architecture
Description	Ephrin-B2 precursor (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L).

ITIH3_MOUSE
NC score	0.010181 (rank : 425)	θ value	3.0926 (rank : 367)
Query Neighborhood Hits	435	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q61704	Gene names	Itih3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3).

FGD1_MOUSE
NC score	0.009700 (rank : 426)	θ value	6.88961 (rank : 402)
Query Neighborhood Hits	435	Target Neighborhood Hits	387	Shared Neighborhood Hits	32
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

US6NL_HUMAN
NC score	0.009595 (rank : 427)	θ value	1.38821 (rank : 339)
Query Neighborhood Hits	435	Target Neighborhood Hits	201	Shared Neighborhood Hits	18
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

DUS16_HUMAN
NC score	0.009377 (rank : 428)	θ value	0.163984 (rank : 292)
Query Neighborhood Hits	435	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

EFNB2_MOUSE
NC score	0.008235 (rank : 429)	θ value	5.27518 (rank : 386)
Query Neighborhood Hits	435	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	P52800	Gene names	Efnb2, Elf2, Epl5, Eplg5, Htkl, Lerk5
Domain Architecture
Description	Ephrin-B2 precursor (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L) (ELF-2).

PHF12_HUMAN
NC score	0.008057 (rank : 430)	θ value	2.36792 (rank : 354)
Query Neighborhood Hits	435	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

MYO9B_HUMAN
NC score	0.007908 (rank : 431)	θ value	0.21417 (rank : 300)
Query Neighborhood Hits	435	Target Neighborhood Hits	641	Shared Neighborhood Hits	47
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

CD320_HUMAN
NC score	0.007738 (rank : 432)	θ value	4.03905 (rank : 374)
Query Neighborhood Hits	435	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

RASF2_MOUSE
NC score	0.007677 (rank : 433)	θ value	1.81305 (rank : 344)
Query Neighborhood Hits	435	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BMS9, Q6A0B2	Gene names	Rassf2, Kiaa0168
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 2.

NRX2B_HUMAN
NC score	0.007389 (rank : 434)	θ value	8.99809 (rank : 428)
Query Neighborhood Hits	435	Target Neighborhood Hits	481	Shared Neighborhood Hits	30
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

TTLL5_MOUSE
NC score	0.007388 (rank : 435)	θ value	4.03905 (rank : 382)
Query Neighborhood Hits	435	Target Neighborhood Hits	150	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

FLVC2_MOUSE
NC score	0.007347 (rank : 436)	θ value	4.03905 (rank : 377)
Query Neighborhood Hits	435	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q91X85	Gene names	Flvcr2
Domain Architecture	No domain graphic available
Description	Feline leukemia virus subgroup C receptor-related protein 2 (Calcium- chelate transporter) (CCT).

APBB2_MOUSE
NC score	0.007169 (rank : 437)	θ value	2.36792 (rank : 347)
Query Neighborhood Hits	435	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DBR4, Q6DFX8	Gene names	Apbb2
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2.

ITIH3_HUMAN
NC score	0.007097 (rank : 438)	θ value	8.99809 (rank : 421)
Query Neighborhood Hits	435	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).

SI1L3_HUMAN
NC score	0.007090 (rank : 439)	θ value	5.27518 (rank : 393)
Query Neighborhood Hits	435	Target Neighborhood Hits	305	Shared Neighborhood Hits	28
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SRPK2_HUMAN
NC score	0.006721 (rank : 440)	θ value	2.36792 (rank : 357)
Query Neighborhood Hits	435	Target Neighborhood Hits	664	Shared Neighborhood Hits	18
SwissProt Accessions	P78362, O75220, O75221, Q6NUL0, Q6V1X2, Q8IYQ3	Gene names	SRPK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

PUR2_MOUSE
NC score	0.006698 (rank : 441)	θ value	5.27518 (rank : 392)
Query Neighborhood Hits	435	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q64737, Q6NS48	Gene names	Gart
Domain Architecture
Description	Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIRS) (Phosphoribosyl-aminoimidazole synthetase) (AIR synthase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (GART) (GAR transformylase) (5'-phosphoribosylglycinamide transformylase)].

PGCA_MOUSE
NC score	0.006668 (rank : 442)	θ value	0.279714 (rank : 305)
Query Neighborhood Hits	435	Target Neighborhood Hits	643	Shared Neighborhood Hits	33
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

WDR20_HUMAN
NC score	0.006408 (rank : 443)	θ value	2.36792 (rank : 360)
Query Neighborhood Hits	435	Target Neighborhood Hits	249	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TBZ3, Q8WXX2, Q9UF86	Gene names	WDR20
Domain Architecture
Description	WD repeat protein 20 (DMR protein).

FRS3_MOUSE
NC score	0.005748 (rank : 444)	θ value	8.99809 (rank : 419)
Query Neighborhood Hits	435	Target Neighborhood Hits	168	Shared Neighborhood Hits	13
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

MAK_MOUSE
NC score	0.005444 (rank : 445)	θ value	1.06291 (rank : 331)
Query Neighborhood Hits	435	Target Neighborhood Hits	873	Shared Neighborhood Hits	25
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

CDKL5_HUMAN
NC score	0.004973 (rank : 446)	θ value	8.99809 (rank : 417)
Query Neighborhood Hits	435	Target Neighborhood Hits	967	Shared Neighborhood Hits	29
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

IL3B2_MOUSE
NC score	0.004138 (rank : 447)	θ value	6.88961 (rank : 405)
Query Neighborhood Hits	435	Target Neighborhood Hits	372	Shared Neighborhood Hits	18
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

PALM_MOUSE
NC score	0.004065 (rank : 448)	θ value	8.99809 (rank : 429)
Query Neighborhood Hits	435	Target Neighborhood Hits	228	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

RNF31_HUMAN
NC score	0.003300 (rank : 449)	θ value	6.88961 (rank : 411)
Query Neighborhood Hits	435	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

THSD1_MOUSE
NC score	0.003214 (rank : 450)	θ value	5.27518 (rank : 397)
Query Neighborhood Hits	435	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

DCJ14_HUMAN
NC score	0.002813 (rank : 451)	θ value	4.03905 (rank : 375)
Query Neighborhood Hits	435	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q6Y2X3, Q66K17, Q96N59, Q96T63	Gene names	DNAJC14, DRIP78
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 14 (Dopamine receptor-interacting protein of 78 kDa) (DRiP78).

GP112_HUMAN
NC score	0.002321 (rank : 452)	θ value	8.99809 (rank : 420)
Query Neighborhood Hits	435	Target Neighborhood Hits	441	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

FRM4A_MOUSE
NC score	0.002236 (rank : 453)	θ value	2.36792 (rank : 349)
Query Neighborhood Hits	435	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

CAC1B_MOUSE
NC score	0.002235 (rank : 454)	θ value	8.99809 (rank : 416)
Query Neighborhood Hits	435	Target Neighborhood Hits	351	Shared Neighborhood Hits	29
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

PTPRV_MOUSE
NC score	-0.001651 (rank : 455)	θ value	6.88961 (rank : 410)
Query Neighborhood Hits	435	Target Neighborhood Hits	179	Shared Neighborhood Hits	5
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PUNC_MOUSE
NC score	-0.002058 (rank : 456)	θ value	1.81305 (rank : 343)
Query Neighborhood Hits	435	Target Neighborhood Hits	501	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

PCD12_HUMAN
NC score	-0.004240 (rank : 457)	θ value	8.99809 (rank : 430)
Query Neighborhood Hits	435	Target Neighborhood Hits	203	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NPG4, Q6UXB6, Q96KB8, Q9H7Y6, Q9H8E0	Gene names	PCDH12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

GLIS1_HUMAN
NC score	-0.011663 (rank : 458)	θ value	2.36792 (rank : 350)
Query Neighborhood Hits	435	Target Neighborhood Hits	748	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

ZN142_HUMAN
NC score	-0.011816 (rank : 459)	θ value	4.03905 (rank : 384)
Query Neighborhood Hits	435	Target Neighborhood Hits	1007	Shared Neighborhood Hits	26
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

ZN324_HUMAN
NC score	-0.013943 (rank : 460)	θ value	8.99809 (rank : 435)
Query Neighborhood Hits	435	Target Neighborhood Hits	765	Shared Neighborhood Hits	9
SwissProt Accessions	O75467	Gene names	ZNF324
Domain Architecture
Description	Zinc finger protein 324 (Zinc finger protein ZF5128).