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Network neighborhood for query Sequence : JHD2B_HUMAN

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JHD2B_HUMAN
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

JHD2A_HUMAN
θ value	0 (rank : 1)	NC score	0.957381 (rank : 3)
Query Neighborhood Hits	171	Target Neighborhood Hits	118	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2A_MOUSE
θ value	0 (rank : 2)	NC score	0.953443 (rank : 4)
Query Neighborhood Hits	171	Target Neighborhood Hits	123	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2B_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	171	Target Neighborhood Hits	171	Shared Neighborhood Hits	171
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

JHD2B_MOUSE
θ value	0 (rank : 4)	NC score	0.982204 (rank : 2)
Query Neighborhood Hits	171	Target Neighborhood Hits	115	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

JHD2C_HUMAN
θ value	0 (rank : 5)	NC score	0.912984 (rank : 6)
Query Neighborhood Hits	171	Target Neighborhood Hits	279	Shared Neighborhood Hits	18
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

JHD2C_MOUSE
θ value	0 (rank : 6)	NC score	0.921815 (rank : 5)
Query Neighborhood Hits	171	Target Neighborhood Hits	297	Shared Neighborhood Hits	22
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

HAIR_MOUSE
θ value	4.122e-45 (rank : 7)	NC score	0.766659 (rank : 7)
Query Neighborhood Hits	171	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

HAIR_HUMAN
θ value	1.32601e-43 (rank : 8)	NC score	0.760947 (rank : 8)
Query Neighborhood Hits	171	Target Neighborhood Hits	172	Shared Neighborhood Hits	17
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

AFF2_MOUSE
θ value	0.0148317 (rank : 9)	NC score	0.056116 (rank : 12)
Query Neighborhood Hits	171	Target Neighborhood Hits	225	Shared Neighborhood Hits	21
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

COBA1_HUMAN
θ value	0.0193708 (rank : 10)	NC score	0.047455 (rank : 18)
Query Neighborhood Hits	171	Target Neighborhood Hits	491	Shared Neighborhood Hits	32
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	0.0193708 (rank : 11)	NC score	0.046942 (rank : 19)
Query Neighborhood Hits	171	Target Neighborhood Hits	487	Shared Neighborhood Hits	29
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

SRRM1_HUMAN
θ value	0.0193708 (rank : 12)	NC score	0.055929 (rank : 13)
Query Neighborhood Hits	171	Target Neighborhood Hits	690	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

DOCK4_MOUSE
θ value	0.0330416 (rank : 13)	NC score	0.038959 (rank : 32)
Query Neighborhood Hits	171	Target Neighborhood Hits	210	Shared Neighborhood Hits	24
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

IWS1_HUMAN
θ value	0.0330416 (rank : 14)	NC score	0.059585 (rank : 11)
Query Neighborhood Hits	171	Target Neighborhood Hits	1241	Shared Neighborhood Hits	47
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TGON2_HUMAN
θ value	0.0330416 (rank : 15)	NC score	0.047845 (rank : 16)
Query Neighborhood Hits	171	Target Neighborhood Hits	1037	Shared Neighborhood Hits	61
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

EDD1_HUMAN
θ value	0.125558 (rank : 16)	NC score	0.037070 (rank : 40)
Query Neighborhood Hits	171	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

MUC1_MOUSE
θ value	0.125558 (rank : 17)	NC score	0.052541 (rank : 14)
Query Neighborhood Hits	171	Target Neighborhood Hits	388	Shared Neighborhood Hits	32
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

UBP37_HUMAN
θ value	0.125558 (rank : 18)	NC score	0.024300 (rank : 74)
Query Neighborhood Hits	171	Target Neighborhood Hits	208	Shared Neighborhood Hits	7
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

ANK2_HUMAN
θ value	0.163984 (rank : 19)	NC score	0.024325 (rank : 73)
Query Neighborhood Hits	171	Target Neighborhood Hits	1615	Shared Neighborhood Hits	75
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CO6A1_HUMAN
θ value	0.163984 (rank : 20)	NC score	0.034894 (rank : 46)
Query Neighborhood Hits	171	Target Neighborhood Hits	264	Shared Neighborhood Hits	23
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

DMP1_MOUSE
θ value	0.163984 (rank : 21)	NC score	0.045871 (rank : 22)
Query Neighborhood Hits	171	Target Neighborhood Hits	498	Shared Neighborhood Hits	21
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

EDD1_MOUSE
θ value	0.163984 (rank : 22)	NC score	0.036452 (rank : 42)
Query Neighborhood Hits	171	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

INSM1_MOUSE
θ value	0.163984 (rank : 23)	NC score	0.019930 (rank : 79)
Query Neighborhood Hits	171	Target Neighborhood Hits	678	Shared Neighborhood Hits	12
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

SENP1_MOUSE
θ value	0.163984 (rank : 24)	NC score	0.027487 (rank : 66)
Query Neighborhood Hits	171	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

GRIPE_HUMAN
θ value	0.21417 (rank : 25)	NC score	0.041172 (rank : 25)
Query Neighborhood Hits	171	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GRIPE_MOUSE
θ value	0.279714 (rank : 26)	NC score	0.040953 (rank : 27)
Query Neighborhood Hits	171	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GLI3_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.008225 (rank : 140)
Query Neighborhood Hits	171	Target Neighborhood Hits	871	Shared Neighborhood Hits	24
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

FOXP2_HUMAN
θ value	0.47712 (rank : 28)	NC score	0.017716 (rank : 90)
Query Neighborhood Hits	171	Target Neighborhood Hits	366	Shared Neighborhood Hits	12
SwissProt Accessions	O15409, Q6ZND1, Q75MJ3, Q8IZE0, Q8N0W2, Q8N6B7, Q8N6B8, Q8NFQ1, Q8NFQ2, Q8NFQ3, Q8NFQ4, Q8TD74	Gene names	FOXP2, CAGH44, TNRC10
Domain Architecture
Description	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein).

FOXP2_MOUSE
θ value	0.47712 (rank : 29)	NC score	0.017703 (rank : 91)
Query Neighborhood Hits	171	Target Neighborhood Hits	366	Shared Neighborhood Hits	12
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

NU214_HUMAN
θ value	0.47712 (rank : 30)	NC score	0.038586 (rank : 34)
Query Neighborhood Hits	171	Target Neighborhood Hits	657	Shared Neighborhood Hits	36
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PIAS4_HUMAN
θ value	0.47712 (rank : 31)	NC score	0.017729 (rank : 88)
Query Neighborhood Hits	171	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N2W9, O75926, Q96G19, Q9UN16	Gene names	PIAS4, PIASG
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

SEN34_MOUSE
θ value	0.47712 (rank : 32)	NC score	0.033153 (rank : 51)
Query Neighborhood Hits	171	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

ADCY3_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.016923 (rank : 96)
Query Neighborhood Hits	171	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	O60266, Q9UDB1	Gene names	ADCY3, KIAA0511
Domain Architecture
Description	Adenylate cyclase type 3 (EC 4.6.1.1) (Adenylate cyclase type III) (Adenylate cyclase, olfactive type) (ATP pyrophosphate-lyase 3) (Adenylyl cyclase 3) (AC-III) (AC3).

CO5A1_HUMAN
θ value	0.62314 (rank : 34)	NC score	0.047602 (rank : 17)
Query Neighborhood Hits	171	Target Neighborhood Hits	434	Shared Neighborhood Hits	34
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CO5A1_MOUSE
θ value	0.62314 (rank : 35)	NC score	0.046576 (rank : 20)
Query Neighborhood Hits	171	Target Neighborhood Hits	419	Shared Neighborhood Hits	29
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

PCLO_MOUSE
θ value	0.62314 (rank : 36)	NC score	0.039390 (rank : 31)
Query Neighborhood Hits	171	Target Neighborhood Hits	2275	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

REXO1_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.041764 (rank : 24)
Query Neighborhood Hits	171	Target Neighborhood Hits	242	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

ANKS6_MOUSE
θ value	0.813845 (rank : 38)	NC score	0.016295 (rank : 102)
Query Neighborhood Hits	171	Target Neighborhood Hits	435	Shared Neighborhood Hits	16
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ARTN_MOUSE
θ value	0.813845 (rank : 39)	NC score	0.029769 (rank : 61)
Query Neighborhood Hits	171	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0L2, Q3SXF4, Q3SXF5	Gene names	Artn
Domain Architecture	No domain graphic available
Description	Artemin precursor.

HXD9_MOUSE
θ value	0.813845 (rank : 40)	NC score	0.006394 (rank : 155)
Query Neighborhood Hits	171	Target Neighborhood Hits	359	Shared Neighborhood Hits	5
SwissProt Accessions	P28357, Q3UYS2	Gene names	Hoxd9, Hox-4.4, Hoxd-9
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4.4) (Hox-5.2).

LAP2A_HUMAN
θ value	0.813845 (rank : 41)	NC score	0.030757 (rank : 58)
Query Neighborhood Hits	171	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P42166, P08918, P08919, Q14860, Q16295	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

PKHF1_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.040939 (rank : 28)
Query Neighborhood Hits	171	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PGCA_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.017056 (rank : 94)
Query Neighborhood Hits	171	Target Neighborhood Hits	821	Shared Neighborhood Hits	44
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PKHF1_MOUSE
θ value	1.06291 (rank : 44)	NC score	0.039897 (rank : 30)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

RHG06_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.028548 (rank : 64)
Query Neighborhood Hits	171	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

DAB2_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.025586 (rank : 70)
Query Neighborhood Hits	171	Target Neighborhood Hits	197	Shared Neighborhood Hits	13
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

K0460_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.029134 (rank : 62)
Query Neighborhood Hits	171	Target Neighborhood Hits	374	Shared Neighborhood Hits	27
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

KLF14_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.003051 (rank : 166)
Query Neighborhood Hits	171	Target Neighborhood Hits	725	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

MFRP_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.017444 (rank : 93)
Query Neighborhood Hits	171	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

PRG4_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.033097 (rank : 52)
Query Neighborhood Hits	171	Target Neighborhood Hits	764	Shared Neighborhood Hits	41
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RHG06_MOUSE
θ value	1.38821 (rank : 51)	NC score	0.018280 (rank : 84)
Query Neighborhood Hits	171	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

SET1A_HUMAN
θ value	1.38821 (rank : 52)	NC score	0.034966 (rank : 45)
Query Neighborhood Hits	171	Target Neighborhood Hits	690	Shared Neighborhood Hits	39
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SRRM1_MOUSE
θ value	1.38821 (rank : 53)	NC score	0.046156 (rank : 21)
Query Neighborhood Hits	171	Target Neighborhood Hits	966	Shared Neighborhood Hits	51
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TGBR3_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.033759 (rank : 48)
Query Neighborhood Hits	171	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

ACINU_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.035197 (rank : 44)
Query Neighborhood Hits	171	Target Neighborhood Hits	828	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

BSN_MOUSE
θ value	1.81305 (rank : 56)	NC score	0.037119 (rank : 39)
Query Neighborhood Hits	171	Target Neighborhood Hits	2057	Shared Neighborhood Hits	92
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

COBA2_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.040526 (rank : 29)
Query Neighborhood Hits	171	Target Neighborhood Hits	408	Shared Neighborhood Hits	32
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COBA2_MOUSE
θ value	1.81305 (rank : 58)	NC score	0.041111 (rank : 26)
Query Neighborhood Hits	171	Target Neighborhood Hits	501	Shared Neighborhood Hits	35
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

EPC2_MOUSE
θ value	1.81305 (rank : 59)	NC score	0.015343 (rank : 109)
Query Neighborhood Hits	171	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

MYST3_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.017052 (rank : 95)
Query Neighborhood Hits	171	Target Neighborhood Hits	772	Shared Neighborhood Hits	27
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NU153_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.036049 (rank : 43)
Query Neighborhood Hits	171	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

PO121_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.033869 (rank : 47)
Query Neighborhood Hits	171	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PWWP2_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.026361 (rank : 69)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

RBBP6_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.033308 (rank : 50)
Query Neighborhood Hits	171	Target Neighborhood Hits	1014	Shared Neighborhood Hits	40
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RREB1_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.006302 (rank : 157)
Query Neighborhood Hits	171	Target Neighborhood Hits	879	Shared Neighborhood Hits	32
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

SEMG1_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.025274 (rank : 71)
Query Neighborhood Hits	171	Target Neighborhood Hits	200	Shared Neighborhood Hits	14
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

UB2J1_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.031489 (rank : 53)
Query Neighborhood Hits	171	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y385, Q5W0N4, Q9BZ32, Q9NQL3, Q9NY66, Q9P011, Q9P0S0, Q9UF10	Gene names	UBE2J1, NCUBE1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HSUBC6e).

DOCK4_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.024388 (rank : 72)
Query Neighborhood Hits	171	Target Neighborhood Hits	237	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DSCL1_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.005616 (rank : 160)
Query Neighborhood Hits	171	Target Neighborhood Hits	589	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

ENAM_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.031088 (rank : 56)
Query Neighborhood Hits	171	Target Neighborhood Hits	229	Shared Neighborhood Hits	25
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

GLI3_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.006361 (rank : 156)
Query Neighborhood Hits	171	Target Neighborhood Hits	807	Shared Neighborhood Hits	20
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

GP152_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.013086 (rank : 118)
Query Neighborhood Hits	171	Target Neighborhood Hits	607	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

MCPH1_MOUSE
θ value	2.36792 (rank : 73)	NC score	0.038611 (rank : 33)
Query Neighborhood Hits	171	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

MDC1_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.037512 (rank : 37)
Query Neighborhood Hits	171	Target Neighborhood Hits	1446	Shared Neighborhood Hits	68
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NOCT_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.018388 (rank : 83)
Query Neighborhood Hits	171	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UK39, Q9HD93, Q9HD94, Q9HD95	Gene names	CCRN4L, CCR4, NOC
Domain Architecture
Description	Nocturnin (CCR4 protein homolog).

TRIPC_HUMAN
θ value	2.36792 (rank : 76)	NC score	0.023652 (rank : 77)
Query Neighborhood Hits	171	Target Neighborhood Hits	319	Shared Neighborhood Hits	23
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

AFF1_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.052310 (rank : 15)
Query Neighborhood Hits	171	Target Neighborhood Hits	506	Shared Neighborhood Hits	34
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

BRCA2_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.015043 (rank : 111)
Query Neighborhood Hits	171	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

CO2A1_HUMAN
θ value	3.0926 (rank : 79)	NC score	0.038224 (rank : 36)
Query Neighborhood Hits	171	Target Neighborhood Hits	486	Shared Neighborhood Hits	31
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO4A2_MOUSE
θ value	3.0926 (rank : 80)	NC score	0.030517 (rank : 60)
Query Neighborhood Hits	171	Target Neighborhood Hits	492	Shared Neighborhood Hits	29
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CO5A3_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.037467 (rank : 38)
Query Neighborhood Hits	171	Target Neighborhood Hits	433	Shared Neighborhood Hits	27
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

EHMT2_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.015586 (rank : 105)
Query Neighborhood Hits	171	Target Neighborhood Hits	750	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

HORN_MOUSE
θ value	3.0926 (rank : 83)	NC score	0.016803 (rank : 99)
Query Neighborhood Hits	171	Target Neighborhood Hits	218	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

MUC13_MOUSE
θ value	3.0926 (rank : 84)	NC score	0.023800 (rank : 76)
Query Neighborhood Hits	171	Target Neighborhood Hits	447	Shared Neighborhood Hits	24
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PCBP4_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.011871 (rank : 125)
Query Neighborhood Hits	171	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

RRBP1_MOUSE
θ value	3.0926 (rank : 86)	NC score	0.016870 (rank : 97)
Query Neighborhood Hits	171	Target Neighborhood Hits	1650	Shared Neighborhood Hits	45
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

TAB2_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.014991 (rank : 112)
Query Neighborhood Hits	171	Target Neighborhood Hits	169	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYJ8, O94838, Q6I9W8, Q76N06, Q9UFP7	Gene names	MAP3K7IP2, KIAA0733, TAB2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2).

TAF3_MOUSE
θ value	3.0926 (rank : 88)	NC score	0.016453 (rank : 100)
Query Neighborhood Hits	171	Target Neighborhood Hits	463	Shared Neighborhood Hits	21
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

UBP4_MOUSE
θ value	3.0926 (rank : 89)	NC score	0.009037 (rank : 135)
Query Neighborhood Hits	171	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

BTAF1_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.006174 (rank : 158)
Query Neighborhood Hits	171	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

C8AP2_MOUSE
θ value	4.03905 (rank : 91)	NC score	0.014597 (rank : 113)
Query Neighborhood Hits	171	Target Neighborhood Hits	405	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CO2A1_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.036737 (rank : 41)
Query Neighborhood Hits	171	Target Neighborhood Hits	483	Shared Neighborhood Hits	31
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO7A1_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.027915 (rank : 65)
Query Neighborhood Hits	171	Target Neighborhood Hits	807	Shared Neighborhood Hits	38
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

EMIL1_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.024251 (rank : 75)
Query Neighborhood Hits	171	Target Neighborhood Hits	239	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

GOGA3_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.003140 (rank : 165)
Query Neighborhood Hits	171	Target Neighborhood Hits	1437	Shared Neighborhood Hits	18
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

MUC2_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.017526 (rank : 92)
Query Neighborhood Hits	171	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PDXL2_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.038368 (rank : 35)
Query Neighborhood Hits	171	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

PTPRN_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.007424 (rank : 145)
Query Neighborhood Hits	171	Target Neighborhood Hits	156	Shared Neighborhood Hits	11
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PURA_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.016083 (rank : 103)
Query Neighborhood Hits	171	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q00577	Gene names	PURA, PUR1
Domain Architecture
Description	Transcriptional activator protein Pur-alpha (Purine-rich single- stranded DNA-binding protein alpha).

SF3A2_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.019710 (rank : 82)
Query Neighborhood Hits	171	Target Neighborhood Hits	263	Shared Neighborhood Hits	11
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SP6_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.002178 (rank : 167)
Query Neighborhood Hits	171	Target Neighborhood Hits	704	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ESX2, Q6VM22	Gene names	Sp6, Epfn, Klf14
Domain Architecture	No domain graphic available
Description	Transcription factor Sp6 (Krueppel-like factor 14) (Epiprofin).

SRRM2_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.075828 (rank : 9)
Query Neighborhood Hits	171	Target Neighborhood Hits	1470	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SSH1_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.007270 (rank : 148)
Query Neighborhood Hits	171	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

TSH3_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.008339 (rank : 139)
Query Neighborhood Hits	171	Target Neighborhood Hits	590	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

WASIP_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.027411 (rank : 67)
Query Neighborhood Hits	171	Target Neighborhood Hits	458	Shared Neighborhood Hits	29
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BSN_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.031374 (rank : 54)
Query Neighborhood Hits	171	Target Neighborhood Hits	1537	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CD248_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.008405 (rank : 138)
Query Neighborhood Hits	171	Target Neighborhood Hits	679	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CMTA2_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.017793 (rank : 87)
Query Neighborhood Hits	171	Target Neighborhood Hits	216	Shared Neighborhood Hits	13
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CO3A1_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.042843 (rank : 23)
Query Neighborhood Hits	171	Target Neighborhood Hits	466	Shared Neighborhood Hits	33
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CSTF3_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.016328 (rank : 101)
Query Neighborhood Hits	171	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LI7	Gene names	Cstf3
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 77 kDa subunit (CSTF 77 kDa subunit) (CF-1 77 kDa subunit) (CstF-77).

LDB3_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.008515 (rank : 137)
Query Neighborhood Hits	171	Target Neighborhood Hits	497	Shared Neighborhood Hits	26
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

MPP5_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.006902 (rank : 150)
Query Neighborhood Hits	171	Target Neighborhood Hits	231	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MUC5B_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.018033 (rank : 85)
Query Neighborhood Hits	171	Target Neighborhood Hits	1020	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

SETB1_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.013580 (rank : 117)
Query Neighborhood Hits	171	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SP2_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.001628 (rank : 169)
Query Neighborhood Hits	171	Target Neighborhood Hits	747	Shared Neighborhood Hits	13
SwissProt Accessions	Q02086	Gene names	SP2, KIAA0048
Domain Architecture
Description	Transcription factor Sp2.

ST5_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.009236 (rank : 133)
Query Neighborhood Hits	171	Target Neighborhood Hits	126	Shared Neighborhood Hits	15
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

STIM1_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.011964 (rank : 122)
Query Neighborhood Hits	171	Target Neighborhood Hits	665	Shared Neighborhood Hits	13
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

WNK1_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.000044 (rank : 170)
Query Neighborhood Hits	171	Target Neighborhood Hits	1158	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ZBTB4_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.003287 (rank : 164)
Query Neighborhood Hits	171	Target Neighborhood Hits	926	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

ZEP1_MOUSE
θ value	5.27518 (rank : 120)	NC score	0.006765 (rank : 151)
Query Neighborhood Hits	171	Target Neighborhood Hits	1063	Shared Neighborhood Hits	41
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

BI2L1_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.009046 (rank : 134)
Query Neighborhood Hits	171	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

CF010_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.017716 (rank : 89)
Query Neighborhood Hits	171	Target Neighborhood Hits	329	Shared Neighborhood Hits	13
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CO6A2_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.028602 (rank : 63)
Query Neighborhood Hits	171	Target Neighborhood Hits	260	Shared Neighborhood Hits	23
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

CONA1_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.030551 (rank : 59)
Query Neighborhood Hits	171	Target Neighborhood Hits	281	Shared Neighborhood Hits	24
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CONA1_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.030864 (rank : 57)
Query Neighborhood Hits	171	Target Neighborhood Hits	254	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CSTF3_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.015292 (rank : 110)
Query Neighborhood Hits	171	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q12996, Q96FQ8, Q96QD6	Gene names	CSTF3
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 77 kDa subunit (CSTF 77 kDa subunit) (CF-1 77 kDa subunit) (CstF-77).

DTX2_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.009287 (rank : 131)
Query Neighborhood Hits	171	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

E2F1_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.006954 (rank : 149)
Query Neighborhood Hits	171	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

FANCJ_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.016863 (rank : 98)
Query Neighborhood Hits	171	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

FBX42_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.010129 (rank : 129)
Query Neighborhood Hits	171	Target Neighborhood Hits	121	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FOXM1_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.013828 (rank : 115)
Query Neighborhood Hits	171	Target Neighborhood Hits	167	Shared Neighborhood Hits	15
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

IF4B_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.021112 (rank : 78)
Query Neighborhood Hits	171	Target Neighborhood Hits	417	Shared Neighborhood Hits	28
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IF4B_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.019885 (rank : 80)
Query Neighborhood Hits	171	Target Neighborhood Hits	368	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

LARP4_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.015471 (rank : 108)
Query Neighborhood Hits	171	Target Neighborhood Hits	260	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

LDB3_MOUSE
θ value	6.88961 (rank : 135)	NC score	0.007994 (rank : 142)
Query Neighborhood Hits	171	Target Neighborhood Hits	510	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

LPP_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.012496 (rank : 120)
Query Neighborhood Hits	171	Target Neighborhood Hits	775	Shared Neighborhood Hits	39
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MBRL_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.011867 (rank : 126)
Query Neighborhood Hits	171	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIV2, Q68EE1, Q6KAN7, Q7TS84, Q8CIV1, Q99K29	Gene names	ORF61
Domain Architecture	No domain graphic available
Description	Membralin.

MPP5_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.006431 (rank : 153)
Query Neighborhood Hits	171	Target Neighborhood Hits	226	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

NCA11_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.004941 (rank : 161)
Query Neighborhood Hits	171	Target Neighborhood Hits	661	Shared Neighborhood Hits	23
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCOA2_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.015494 (rank : 107)
Query Neighborhood Hits	171	Target Neighborhood Hits	281	Shared Neighborhood Hits	23
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NEBU_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.008183 (rank : 141)
Query Neighborhood Hits	171	Target Neighborhood Hits	420	Shared Neighborhood Hits	8
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

PCBP4_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.009756 (rank : 130)
Query Neighborhood Hits	171	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PCNP_HUMAN
θ value	6.88961 (rank : 143)	NC score	0.015562 (rank : 106)
Query Neighborhood Hits	171	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WW12, Q6AI44, Q96CU3, Q9NS81	Gene names	PCNP
Domain Architecture	No domain graphic available
Description	PEST proteolytic signal-containing nuclear protein (PEST-containing nuclear protein) (PCNP).

PI5PA_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.017832 (rank : 86)
Query Neighborhood Hits	171	Target Neighborhood Hits	749	Shared Neighborhood Hits	53
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PTN23_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.006425 (rank : 154)
Query Neighborhood Hits	171	Target Neighborhood Hits	726	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PURB_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.014036 (rank : 114)
Query Neighborhood Hits	171	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	O35295	Gene names	Purb
Domain Architecture	No domain graphic available
Description	Transcriptional activator protein Pur-beta (Purine-rich element- binding protein B) (Vascular actin single-stranded DNA-binding factor 2 p44 component).

SCEL_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.013668 (rank : 116)
Query Neighborhood Hits	171	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	O95171	Gene names	SCEL
Domain Architecture
Description	Sciellin.

SPN90_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.011957 (rank : 123)
Query Neighborhood Hits	171	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

SRRM2_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.066342 (rank : 10)
Query Neighborhood Hits	171	Target Neighborhood Hits	1296	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ZN142_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.000022 (rank : 171)
Query Neighborhood Hits	171	Target Neighborhood Hits	1007	Shared Neighborhood Hits	30
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

AAKG2_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.006004 (rank : 159)
Query Neighborhood Hits	171	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WG5, Q6V7V5	Gene names	Prkag2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2).

CABYR_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.012235 (rank : 121)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

CACB2_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.007785 (rank : 143)
Query Neighborhood Hits	171	Target Neighborhood Hits	99	Shared Neighborhood Hits	10
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CACB2_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.007605 (rank : 144)
Query Neighborhood Hits	171	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

CO9A1_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.027250 (rank : 68)
Query Neighborhood Hits	171	Target Neighborhood Hits	420	Shared Neighborhood Hits	26
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

FA48A_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.009015 (rank : 136)
Query Neighborhood Hits	171	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

IWS1_MOUSE
θ value	8.99809 (rank : 157)	NC score	0.031236 (rank : 55)
Query Neighborhood Hits	171	Target Neighborhood Hits	1258	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KAISO_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.001909 (rank : 168)
Query Neighborhood Hits	171	Target Neighborhood Hits	840	Shared Neighborhood Hits	22
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

LPP_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.007333 (rank : 147)
Query Neighborhood Hits	171	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

MDC1_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.033315 (rank : 49)
Query Neighborhood Hits	171	Target Neighborhood Hits	998	Shared Neighborhood Hits	62
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MEGF9_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.004132 (rank : 163)
Query Neighborhood Hits	171	Target Neighborhood Hits	557	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MKRN3_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.009267 (rank : 132)
Query Neighborhood Hits	171	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

NSD1_MOUSE
θ value	8.99809 (rank : 163)	NC score	0.011885 (rank : 124)
Query Neighborhood Hits	171	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

OSBP2_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.004524 (rank : 162)
Query Neighborhood Hits	171	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

SMG5_HUMAN
θ value	8.99809 (rank : 165)	NC score	0.010573 (rank : 127)
Query Neighborhood Hits	171	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

STIM1_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.007414 (rank : 146)
Query Neighborhood Hits	171	Target Neighborhood Hits	660	Shared Neighborhood Hits	12
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

SYMPK_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.012626 (rank : 119)
Query Neighborhood Hits	171	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

TCOF_MOUSE
θ value	8.99809 (rank : 168)	NC score	0.019770 (rank : 81)
Query Neighborhood Hits	171	Target Neighborhood Hits	471	Shared Neighborhood Hits	27
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

UB2J1_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.015720 (rank : 104)
Query Neighborhood Hits	171	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJZ4, Q9DC92	Gene names	Ube2j1, Ncube1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1).

UBP18_MOUSE
θ value	8.99809 (rank : 170)	NC score	0.010313 (rank : 128)
Query Neighborhood Hits	171	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP21_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.006594 (rank : 152)
Query Neighborhood Hits	171	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

Hits sorted by NC score

JHD2B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	171	Target Neighborhood Hits	171	Shared Neighborhood Hits	171
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

JHD2B_MOUSE
NC score	0.982204 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	171	Target Neighborhood Hits	115	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

JHD2A_HUMAN
NC score	0.957381 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	171	Target Neighborhood Hits	118	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4C1, Q53S72, Q68D47, Q68UT9, Q6N050, Q8IY08	Gene names	JMJD1A, JHDM2A, JMJD1, KIAA0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2A_MOUSE
NC score	0.953443 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	171	Target Neighborhood Hits	123	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PCM1, Q2MJQ6, Q3TKW8, Q3UML3, Q6ZQ57, Q8K2J6, Q8K2K4, Q8R350	Gene names	Jmjd1a, Jhdm2a, Kiaa0742
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2A (EC 1.14.11.-) (Jumonji domain-containing protein 1A).

JHD2C_MOUSE
NC score	0.921815 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	171	Target Neighborhood Hits	297	Shared Neighborhood Hits	22
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

JHD2C_HUMAN
NC score	0.912984 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	171	Target Neighborhood Hits	279	Shared Neighborhood Hits	18
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

HAIR_MOUSE
NC score	0.766659 (rank : 7)	θ value	4.122e-45 (rank : 7)
Query Neighborhood Hits	171	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	Q61645, Q80Y47	Gene names	Hr
Domain Architecture
Description	Protein hairless.

HAIR_HUMAN
NC score	0.760947 (rank : 8)	θ value	1.32601e-43 (rank : 8)
Query Neighborhood Hits	171	Target Neighborhood Hits	172	Shared Neighborhood Hits	17
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

SRRM2_MOUSE
NC score	0.075828 (rank : 9)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	171	Target Neighborhood Hits	1470	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM2_HUMAN
NC score	0.066342 (rank : 10)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	171	Target Neighborhood Hits	1296	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

IWS1_HUMAN
NC score	0.059585 (rank : 11)	θ value	0.0330416 (rank : 14)
Query Neighborhood Hits	171	Target Neighborhood Hits	1241	Shared Neighborhood Hits	47
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AFF2_MOUSE
NC score	0.056116 (rank : 12)	θ value	0.0148317 (rank : 9)
Query Neighborhood Hits	171	Target Neighborhood Hits	225	Shared Neighborhood Hits	21
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

SRRM1_HUMAN
NC score	0.055929 (rank : 13)	θ value	0.0193708 (rank : 12)
Query Neighborhood Hits	171	Target Neighborhood Hits	690	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MUC1_MOUSE
NC score	0.052541 (rank : 14)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	171	Target Neighborhood Hits	388	Shared Neighborhood Hits	32
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

AFF1_HUMAN
NC score	0.052310 (rank : 15)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	171	Target Neighborhood Hits	506	Shared Neighborhood Hits	34
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

TGON2_HUMAN
NC score	0.047845 (rank : 16)	θ value	0.0330416 (rank : 15)
Query Neighborhood Hits	171	Target Neighborhood Hits	1037	Shared Neighborhood Hits	61
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CO5A1_HUMAN
NC score	0.047602 (rank : 17)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	171	Target Neighborhood Hits	434	Shared Neighborhood Hits	34
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

COBA1_HUMAN
NC score	0.047455 (rank : 18)	θ value	0.0193708 (rank : 10)
Query Neighborhood Hits	171	Target Neighborhood Hits	491	Shared Neighborhood Hits	32
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
NC score	0.046942 (rank : 19)	θ value	0.0193708 (rank : 11)
Query Neighborhood Hits	171	Target Neighborhood Hits	487	Shared Neighborhood Hits	29
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CO5A1_MOUSE
NC score	0.046576 (rank : 20)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	171	Target Neighborhood Hits	419	Shared Neighborhood Hits	29
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

SRRM1_MOUSE
NC score	0.046156 (rank : 21)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	171	Target Neighborhood Hits	966	Shared Neighborhood Hits	51
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

DMP1_MOUSE
NC score	0.045871 (rank : 22)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	171	Target Neighborhood Hits	498	Shared Neighborhood Hits	21
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

CO3A1_MOUSE
NC score	0.042843 (rank : 23)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	171	Target Neighborhood Hits	466	Shared Neighborhood Hits	33
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

REXO1_HUMAN
NC score	0.041764 (rank : 24)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	171	Target Neighborhood Hits	242	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

GRIPE_HUMAN
NC score	0.041172 (rank : 25)	θ value	0.21417 (rank : 25)
Query Neighborhood Hits	171	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

COBA2_MOUSE
NC score	0.041111 (rank : 26)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	171	Target Neighborhood Hits	501	Shared Neighborhood Hits	35
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

GRIPE_MOUSE
NC score	0.040953 (rank : 27)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	171	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

PKHF1_HUMAN
NC score	0.040939 (rank : 28)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	171	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

COBA2_HUMAN
NC score	0.040526 (rank : 29)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	171	Target Neighborhood Hits	408	Shared Neighborhood Hits	32
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

PKHF1_MOUSE
NC score	0.039897 (rank : 30)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PCLO_MOUSE
NC score	0.039390 (rank : 31)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	171	Target Neighborhood Hits	2275	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

DOCK4_MOUSE
NC score	0.038959 (rank : 32)	θ value	0.0330416 (rank : 13)
Query Neighborhood Hits	171	Target Neighborhood Hits	210	Shared Neighborhood Hits	24
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

MCPH1_MOUSE
NC score	0.038611 (rank : 33)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	171	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

NU214_HUMAN
NC score	0.038586 (rank : 34)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	171	Target Neighborhood Hits	657	Shared Neighborhood Hits	36
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PDXL2_HUMAN
NC score	0.038368 (rank : 35)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	171	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

CO2A1_HUMAN
NC score	0.038224 (rank : 36)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	171	Target Neighborhood Hits	486	Shared Neighborhood Hits	31
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

MDC1_HUMAN
NC score	0.037512 (rank : 37)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	171	Target Neighborhood Hits	1446	Shared Neighborhood Hits	68
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CO5A3_HUMAN
NC score	0.037467 (rank : 38)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	171	Target Neighborhood Hits	433	Shared Neighborhood Hits	27
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

BSN_MOUSE
NC score	0.037119 (rank : 39)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	171	Target Neighborhood Hits	2057	Shared Neighborhood Hits	92
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

EDD1_HUMAN
NC score	0.037070 (rank : 40)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	171	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

CO2A1_MOUSE
NC score	0.036737 (rank : 41)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	171	Target Neighborhood Hits	483	Shared Neighborhood Hits	31
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

EDD1_MOUSE
NC score	0.036452 (rank : 42)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	171	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

NU153_HUMAN
NC score	0.036049 (rank : 43)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	171	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

ACINU_HUMAN
NC score	0.035197 (rank : 44)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	171	Target Neighborhood Hits	828	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SET1A_HUMAN
NC score	0.034966 (rank : 45)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	171	Target Neighborhood Hits	690	Shared Neighborhood Hits	39
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

CO6A1_HUMAN
NC score	0.034894 (rank : 46)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	171	Target Neighborhood Hits	264	Shared Neighborhood Hits	23
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

PO121_HUMAN
NC score	0.033869 (rank : 47)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	171	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

TGBR3_HUMAN
NC score	0.033759 (rank : 48)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	171	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

MDC1_MOUSE
NC score	0.033315 (rank : 49)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	171	Target Neighborhood Hits	998	Shared Neighborhood Hits	62
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

RBBP6_MOUSE
NC score	0.033308 (rank : 50)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	171	Target Neighborhood Hits	1014	Shared Neighborhood Hits	40
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SEN34_MOUSE
NC score	0.033153 (rank : 51)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	171	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

PRG4_HUMAN
NC score	0.033097 (rank : 52)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	171	Target Neighborhood Hits	764	Shared Neighborhood Hits	41
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

UB2J1_HUMAN
NC score	0.031489 (rank : 53)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	171	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y385, Q5W0N4, Q9BZ32, Q9NQL3, Q9NY66, Q9P011, Q9P0S0, Q9UF10	Gene names	UBE2J1, NCUBE1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HSUBC6e).

BSN_HUMAN
NC score	0.031374 (rank : 54)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	171	Target Neighborhood Hits	1537	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

IWS1_MOUSE
NC score	0.031236 (rank : 55)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	171	Target Neighborhood Hits	1258	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ENAM_MOUSE
NC score	0.031088 (rank : 56)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	171	Target Neighborhood Hits	229	Shared Neighborhood Hits	25
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

CONA1_MOUSE
NC score	0.030864 (rank : 57)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	171	Target Neighborhood Hits	254	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

LAP2A_HUMAN
NC score	0.030757 (rank : 58)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	171	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P42166, P08918, P08919, Q14860, Q16295	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

CONA1_HUMAN
NC score	0.030551 (rank : 59)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	171	Target Neighborhood Hits	281	Shared Neighborhood Hits	24
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

CO4A2_MOUSE
NC score	0.030517 (rank : 60)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	171	Target Neighborhood Hits	492	Shared Neighborhood Hits	29
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

ARTN_MOUSE
NC score	0.029769 (rank : 61)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	171	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0L2, Q3SXF4, Q3SXF5	Gene names	Artn
Domain Architecture	No domain graphic available
Description	Artemin precursor.

K0460_MOUSE
NC score	0.029134 (rank : 62)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	171	Target Neighborhood Hits	374	Shared Neighborhood Hits	27
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

CO6A2_MOUSE
NC score	0.028602 (rank : 63)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	171	Target Neighborhood Hits	260	Shared Neighborhood Hits	23
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

RHG06_HUMAN
NC score	0.028548 (rank : 64)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	171	Target Neighborhood Hits	114	Shared Neighborhood Hits	12
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CO7A1_HUMAN
NC score	0.027915 (rank : 65)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	171	Target Neighborhood Hits	807	Shared Neighborhood Hits	38
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

SENP1_MOUSE
NC score	0.027487 (rank : 66)	θ value	0.163984 (rank : 24)
Query Neighborhood Hits	171	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

WASIP_HUMAN
NC score	0.027411 (rank : 67)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	171	Target Neighborhood Hits	458	Shared Neighborhood Hits	29
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

CO9A1_HUMAN
NC score	0.027250 (rank : 68)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	171	Target Neighborhood Hits	420	Shared Neighborhood Hits	26
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

PWWP2_HUMAN
NC score	0.026361 (rank : 69)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

DAB2_HUMAN
NC score	0.025586 (rank : 70)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	171	Target Neighborhood Hits	197	Shared Neighborhood Hits	13
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

SEMG1_HUMAN
NC score	0.025274 (rank : 71)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	171	Target Neighborhood Hits	200	Shared Neighborhood Hits	14
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

DOCK4_HUMAN
NC score	0.024388 (rank : 72)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	171	Target Neighborhood Hits	237	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

ANK2_HUMAN
NC score	0.024325 (rank : 73)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	171	Target Neighborhood Hits	1615	Shared Neighborhood Hits	75
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

UBP37_HUMAN
NC score	0.024300 (rank : 74)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	171	Target Neighborhood Hits	208	Shared Neighborhood Hits	7
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

EMIL1_HUMAN
NC score	0.024251 (rank : 75)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	171	Target Neighborhood Hits	239	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

MUC13_MOUSE
NC score	0.023800 (rank : 76)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	171	Target Neighborhood Hits	447	Shared Neighborhood Hits	24
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

TRIPC_HUMAN
NC score	0.023652 (rank : 77)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	171	Target Neighborhood Hits	319	Shared Neighborhood Hits	23
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

IF4B_HUMAN
NC score	0.021112 (rank : 78)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	171	Target Neighborhood Hits	417	Shared Neighborhood Hits	28
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

INSM1_MOUSE
NC score	0.019930 (rank : 79)	θ value	0.163984 (rank : 23)
Query Neighborhood Hits	171	Target Neighborhood Hits	678	Shared Neighborhood Hits	12
SwissProt Accessions	Q63ZV0, Q9Z113	Gene names	Insm1, Ia1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

IF4B_MOUSE
NC score	0.019885 (rank : 80)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	171	Target Neighborhood Hits	368	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

TCOF_MOUSE
NC score	0.019770 (rank : 81)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	171	Target Neighborhood Hits	471	Shared Neighborhood Hits	27
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

SF3A2_HUMAN
NC score	0.019710 (rank : 82)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	171	Target Neighborhood Hits	263	Shared Neighborhood Hits	11
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

NOCT_HUMAN
NC score	0.018388 (rank : 83)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	171	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UK39, Q9HD93, Q9HD94, Q9HD95	Gene names	CCRN4L, CCR4, NOC
Domain Architecture
Description	Nocturnin (CCR4 protein homolog).

RHG06_MOUSE
NC score	0.018280 (rank : 84)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	171	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

MUC5B_HUMAN
NC score	0.018033 (rank : 85)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	171	Target Neighborhood Hits	1020	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PI5PA_HUMAN
NC score	0.017832 (rank : 86)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	171	Target Neighborhood Hits	749	Shared Neighborhood Hits	53
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

CMTA2_MOUSE
NC score	0.017793 (rank : 87)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	171	Target Neighborhood Hits	216	Shared Neighborhood Hits	13
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

PIAS4_HUMAN
NC score	0.017729 (rank : 88)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	171	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N2W9, O75926, Q96G19, Q9UN16	Gene names	PIAS4, PIASG
Domain Architecture
Description	Protein inhibitor of activated STAT protein 4 (Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy).

CF010_HUMAN
NC score	0.017716 (rank : 89)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	171	Target Neighborhood Hits	329	Shared Neighborhood Hits	13
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

FOXP2_HUMAN
NC score	0.017716 (rank : 90)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	171	Target Neighborhood Hits	366	Shared Neighborhood Hits	12
SwissProt Accessions	O15409, Q6ZND1, Q75MJ3, Q8IZE0, Q8N0W2, Q8N6B7, Q8N6B8, Q8NFQ1, Q8NFQ2, Q8NFQ3, Q8NFQ4, Q8TD74	Gene names	FOXP2, CAGH44, TNRC10
Domain Architecture
Description	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein).

FOXP2_MOUSE
NC score	0.017703 (rank : 91)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	171	Target Neighborhood Hits	366	Shared Neighborhood Hits	12
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

MUC2_HUMAN
NC score	0.017526 (rank : 92)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	171	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MFRP_HUMAN
NC score	0.017444 (rank : 93)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	171	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

PGCA_HUMAN
NC score	0.017056 (rank : 94)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	171	Target Neighborhood Hits	821	Shared Neighborhood Hits	44
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

MYST3_HUMAN
NC score	0.017052 (rank : 95)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	171	Target Neighborhood Hits	772	Shared Neighborhood Hits	27
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

ADCY3_HUMAN
NC score	0.016923 (rank : 96)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	171	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	O60266, Q9UDB1	Gene names	ADCY3, KIAA0511
Domain Architecture
Description	Adenylate cyclase type 3 (EC 4.6.1.1) (Adenylate cyclase type III) (Adenylate cyclase, olfactive type) (ATP pyrophosphate-lyase 3) (Adenylyl cyclase 3) (AC-III) (AC3).

RRBP1_MOUSE
NC score	0.016870 (rank : 97)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	171	Target Neighborhood Hits	1650	Shared Neighborhood Hits	45
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

FANCJ_HUMAN
NC score	0.016863 (rank : 98)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	171	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

HORN_MOUSE
NC score	0.016803 (rank : 99)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	171	Target Neighborhood Hits	218	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

TAF3_MOUSE
NC score	0.016453 (rank : 100)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	171	Target Neighborhood Hits	463	Shared Neighborhood Hits	21
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CSTF3_MOUSE
NC score	0.016328 (rank : 101)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	171	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LI7	Gene names	Cstf3
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 77 kDa subunit (CSTF 77 kDa subunit) (CF-1 77 kDa subunit) (CstF-77).

ANKS6_MOUSE
NC score	0.016295 (rank : 102)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	171	Target Neighborhood Hits	435	Shared Neighborhood Hits	16
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

PURA_HUMAN
NC score	0.016083 (rank : 103)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	171	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q00577	Gene names	PURA, PUR1
Domain Architecture
Description	Transcriptional activator protein Pur-alpha (Purine-rich single- stranded DNA-binding protein alpha).

UB2J1_MOUSE
NC score	0.015720 (rank : 104)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	171	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJZ4, Q9DC92	Gene names	Ube2j1, Ncube1
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 J1 (EC 6.3.2.19) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE1).

EHMT2_MOUSE
NC score	0.015586 (rank : 105)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	171	Target Neighborhood Hits	750	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

PCNP_HUMAN
NC score	0.015562 (rank : 106)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	171	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WW12, Q6AI44, Q96CU3, Q9NS81	Gene names	PCNP
Domain Architecture	No domain graphic available
Description	PEST proteolytic signal-containing nuclear protein (PEST-containing nuclear protein) (PCNP).

NCOA2_MOUSE
NC score	0.015494 (rank : 107)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	171	Target Neighborhood Hits	281	Shared Neighborhood Hits	23
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

LARP4_MOUSE
NC score	0.015471 (rank : 108)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	171	Target Neighborhood Hits	260	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

EPC2_MOUSE
NC score	0.015343 (rank : 109)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	171	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

CSTF3_HUMAN
NC score	0.015292 (rank : 110)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	171	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q12996, Q96FQ8, Q96QD6	Gene names	CSTF3
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 77 kDa subunit (CSTF 77 kDa subunit) (CF-1 77 kDa subunit) (CstF-77).

BRCA2_HUMAN
NC score	0.015043 (rank : 111)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	171	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

TAB2_HUMAN
NC score	0.014991 (rank : 112)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	171	Target Neighborhood Hits	169	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYJ8, O94838, Q6I9W8, Q76N06, Q9UFP7	Gene names	MAP3K7IP2, KIAA0733, TAB2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2).

C8AP2_MOUSE
NC score	0.014597 (rank : 113)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	171	Target Neighborhood Hits	405	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

PURB_MOUSE
NC score	0.014036 (rank : 114)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	171	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	O35295	Gene names	Purb
Domain Architecture	No domain graphic available
Description	Transcriptional activator protein Pur-beta (Purine-rich element- binding protein B) (Vascular actin single-stranded DNA-binding factor 2 p44 component).

FOXM1_HUMAN
NC score	0.013828 (rank : 115)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	171	Target Neighborhood Hits	167	Shared Neighborhood Hits	15
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

SCEL_HUMAN
NC score	0.013668 (rank : 116)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	171	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	O95171	Gene names	SCEL
Domain Architecture
Description	Sciellin.

SETB1_MOUSE
NC score	0.013580 (rank : 117)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	171	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

GP152_MOUSE
NC score	0.013086 (rank : 118)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	171	Target Neighborhood Hits	607	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

SYMPK_MOUSE
NC score	0.012626 (rank : 119)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	171	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

LPP_HUMAN
NC score	0.012496 (rank : 120)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	171	Target Neighborhood Hits	775	Shared Neighborhood Hits	39
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

CABYR_MOUSE
NC score	0.012235 (rank : 121)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	171	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

STIM1_HUMAN
NC score	0.011964 (rank : 122)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	171	Target Neighborhood Hits	665	Shared Neighborhood Hits	13
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

SPN90_MOUSE
NC score	0.011957 (rank : 123)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	171	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

NSD1_MOUSE
NC score	0.011885 (rank : 124)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	171	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PCBP4_MOUSE
NC score	0.011871 (rank : 125)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	171	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

MBRL_MOUSE
NC score	0.011867 (rank : 126)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	171	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIV2, Q68EE1, Q6KAN7, Q7TS84, Q8CIV1, Q99K29	Gene names	ORF61
Domain Architecture	No domain graphic available
Description	Membralin.

SMG5_HUMAN
NC score	0.010573 (rank : 127)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	171	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

UBP18_MOUSE
NC score	0.010313 (rank : 128)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	171	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

FBX42_HUMAN
NC score	0.010129 (rank : 129)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	171	Target Neighborhood Hits	121	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

PCBP4_HUMAN
NC score	0.009756 (rank : 130)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	171	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

DTX2_MOUSE
NC score	0.009287 (rank : 131)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	171	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

MKRN3_HUMAN
NC score	0.009267 (rank : 132)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	171	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

ST5_MOUSE
NC score	0.009236 (rank : 133)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	171	Target Neighborhood Hits	126	Shared Neighborhood Hits	15
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

BI2L1_HUMAN
NC score	0.009046 (rank : 134)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	171	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHR4, Q75L21, Q75L22, Q96CV4, Q9Y2M8	Gene names	BAIAP2L1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1).

UBP4_MOUSE
NC score	0.009037 (rank : 135)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	171	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

FA48A_HUMAN
NC score	0.009015 (rank : 136)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	171	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEM7, Q71RF3, Q9Y6A6	Gene names	FAM48A
Domain Architecture	No domain graphic available
Description	Protein FAM48A (p38-interacting protein) (p38IP).

LDB3_HUMAN
NC score	0.008515 (rank : 137)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	171	Target Neighborhood Hits	497	Shared Neighborhood Hits	26
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

CD248_HUMAN
NC score	0.008405 (rank : 138)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	171	Target Neighborhood Hits	679	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TSH3_MOUSE
NC score	0.008339 (rank : 139)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	171	Target Neighborhood Hits	590	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

GLI3_HUMAN
NC score	0.008225 (rank : 140)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	171	Target Neighborhood Hits	871	Shared Neighborhood Hits	24
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

NEBU_HUMAN
NC score	0.008183 (rank : 141)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	171	Target Neighborhood Hits	420	Shared Neighborhood Hits	8
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

LDB3_MOUSE
NC score	0.007994 (rank : 142)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	171	Target Neighborhood Hits	510	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

CACB2_HUMAN
NC score	0.007785 (rank : 143)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	171	Target Neighborhood Hits	99	Shared Neighborhood Hits	10
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CACB2_MOUSE
NC score	0.007605 (rank : 144)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	171	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

PTPRN_HUMAN
NC score	0.007424 (rank : 145)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	171	Target Neighborhood Hits	156	Shared Neighborhood Hits	11
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

STIM1_MOUSE
NC score	0.007414 (rank : 146)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	171	Target Neighborhood Hits	660	Shared Neighborhood Hits	12
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

LPP_MOUSE
NC score	0.007333 (rank : 147)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	171	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BFW7, Q5U407, Q8BHI1, Q8BKI0, Q8BKN2, Q8BLF4, Q8BLG3, Q8C101	Gene names	Lpp
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner homolog.

SSH1_MOUSE
NC score	0.007270 (rank : 148)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	171	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

E2F1_HUMAN
NC score	0.006954 (rank : 149)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	171	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q01094, Q13143, Q92768	Gene names	E2F1, RBBP3
Domain Architecture
Description	Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).

MPP5_HUMAN
NC score	0.006902 (rank : 150)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	171	Target Neighborhood Hits	231	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

ZEP1_MOUSE
NC score	0.006765 (rank : 151)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	171	Target Neighborhood Hits	1063	Shared Neighborhood Hits	41
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

UBP21_MOUSE
NC score	0.006594 (rank : 152)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	171	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

MPP5_MOUSE
NC score	0.006431 (rank : 153)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	171	Target Neighborhood Hits	226	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

PTN23_MOUSE
NC score	0.006425 (rank : 154)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	171	Target Neighborhood Hits	726	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

HXD9_MOUSE
NC score	0.006394 (rank : 155)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	171	Target Neighborhood Hits	359	Shared Neighborhood Hits	5
SwissProt Accessions	P28357, Q3UYS2	Gene names	Hoxd9, Hox-4.4, Hoxd-9
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4.4) (Hox-5.2).

GLI3_MOUSE
NC score	0.006361 (rank : 156)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	171	Target Neighborhood Hits	807	Shared Neighborhood Hits	20
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

RREB1_HUMAN
NC score	0.006302 (rank : 157)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	171	Target Neighborhood Hits	879	Shared Neighborhood Hits	32
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

BTAF1_HUMAN
NC score	0.006174 (rank : 158)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	171	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

AAKG2_MOUSE
NC score	0.006004 (rank : 159)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	171	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WG5, Q6V7V5	Gene names	Prkag2
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2).

DSCL1_HUMAN
NC score	0.005616 (rank : 160)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	171	Target Neighborhood Hits	589	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

NCA11_MOUSE
NC score	0.004941 (rank : 161)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	171	Target Neighborhood Hits	661	Shared Neighborhood Hits	23
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

OSBP2_HUMAN
NC score	0.004524 (rank : 162)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	171	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

MEGF9_HUMAN
NC score	0.004132 (rank : 163)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	171	Target Neighborhood Hits	557	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ZBTB4_HUMAN
NC score	0.003287 (rank : 164)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	171	Target Neighborhood Hits	926	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

GOGA3_MOUSE
NC score	0.003140 (rank : 165)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	171	Target Neighborhood Hits	1437	Shared Neighborhood Hits	18
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

KLF14_HUMAN
NC score	0.003051 (rank : 166)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	171	Target Neighborhood Hits	725	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

SP6_MOUSE
NC score	0.002178 (rank : 167)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	171	Target Neighborhood Hits	704	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ESX2, Q6VM22	Gene names	Sp6, Epfn, Klf14
Domain Architecture	No domain graphic available
Description	Transcription factor Sp6 (Krueppel-like factor 14) (Epiprofin).

KAISO_HUMAN
NC score	0.001909 (rank : 168)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	171	Target Neighborhood Hits	840	Shared Neighborhood Hits	22
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

SP2_HUMAN
NC score	0.001628 (rank : 169)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	171	Target Neighborhood Hits	747	Shared Neighborhood Hits	13
SwissProt Accessions	Q02086	Gene names	SP2, KIAA0048
Domain Architecture
Description	Transcription factor Sp2.

WNK1_HUMAN
NC score	0.000044 (rank : 170)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	171	Target Neighborhood Hits	1158	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ZN142_HUMAN
NC score	0.000022 (rank : 171)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	171	Target Neighborhood Hits	1007	Shared Neighborhood Hits	30
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).