Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : RHG06_MOUSE

For an explanation of this page, click here

RHG06_MOUSE
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RHG06_HUMAN
θ value	0 (rank : 1)	NC score	0.994230 (rank : 2)
Query Neighborhood Hits	105	Target Neighborhood Hits	114	Shared Neighborhood Hits	73
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	105	Target Neighborhood Hits	105	Shared Neighborhood Hits	105
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

SRGP2_HUMAN
θ value	3.51386e-20 (rank : 3)	NC score	0.718445 (rank : 28)
Query Neighborhood Hits	105	Target Neighborhood Hits	331	Shared Neighborhood Hits	64
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RHG01_HUMAN
θ value	7.82807e-20 (rank : 4)	NC score	0.797782 (rank : 4)
Query Neighborhood Hits	105	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

CHIN_HUMAN
θ value	1.33526e-19 (rank : 5)	NC score	0.719910 (rank : 25)
Query Neighborhood Hits	105	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

SRGP2_MOUSE
θ value	3.88503e-19 (rank : 6)	NC score	0.709881 (rank : 34)
Query Neighborhood Hits	105	Target Neighborhood Hits	324	Shared Neighborhood Hits	63
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

CHIN_MOUSE
θ value	8.65492e-19 (rank : 7)	NC score	0.720867 (rank : 24)
Query Neighborhood Hits	105	Target Neighborhood Hits	229	Shared Neighborhood Hits	62
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

3BP1_HUMAN
θ value	1.92812e-18 (rank : 8)	NC score	0.789350 (rank : 5)
Query Neighborhood Hits	105	Target Neighborhood Hits	376	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG07_HUMAN
θ value	3.28887e-18 (rank : 9)	NC score	0.735516 (rank : 21)
Query Neighborhood Hits	105	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_MOUSE
θ value	1.63225e-17 (rank : 10)	NC score	0.738103 (rank : 19)
Query Neighborhood Hits	105	Target Neighborhood Hits	103	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG12_HUMAN
θ value	2.13179e-17 (rank : 11)	NC score	0.783382 (rank : 8)
Query Neighborhood Hits	105	Target Neighborhood Hits	190	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

3BP1_MOUSE
θ value	4.74913e-17 (rank : 12)	NC score	0.809594 (rank : 3)
Query Neighborhood Hits	105	Target Neighborhood Hits	238	Shared Neighborhood Hits	63
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG12_MOUSE
θ value	4.74913e-17 (rank : 13)	NC score	0.781099 (rank : 9)
Query Neighborhood Hits	105	Target Neighborhood Hits	204	Shared Neighborhood Hits	63
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

STAR8_MOUSE
θ value	1.80466e-16 (rank : 14)	NC score	0.704521 (rank : 36)
Query Neighborhood Hits	105	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

GMIP_MOUSE
θ value	4.02038e-16 (rank : 15)	NC score	0.788944 (rank : 6)
Query Neighborhood Hits	105	Target Neighborhood Hits	202	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

ABR_HUMAN
θ value	5.25075e-16 (rank : 16)	NC score	0.709969 (rank : 33)
Query Neighborhood Hits	105	Target Neighborhood Hits	166	Shared Neighborhood Hits	63
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

MYO9B_HUMAN
θ value	5.25075e-16 (rank : 17)	NC score	0.407908 (rank : 58)
Query Neighborhood Hits	105	Target Neighborhood Hits	641	Shared Neighborhood Hits	68
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
θ value	6.85773e-16 (rank : 18)	NC score	0.413391 (rank : 57)
Query Neighborhood Hits	105	Target Neighborhood Hits	311	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

CHIO_MOUSE
θ value	1.16975e-15 (rank : 19)	NC score	0.744307 (rank : 17)
Query Neighborhood Hits	105	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG08_MOUSE
θ value	1.16975e-15 (rank : 20)	NC score	0.771257 (rank : 14)
Query Neighborhood Hits	105	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

CHIO_HUMAN
θ value	1.52774e-15 (rank : 21)	NC score	0.712451 (rank : 32)
Query Neighborhood Hits	105	Target Neighborhood Hits	220	Shared Neighborhood Hits	61
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

FNBP2_HUMAN
θ value	1.99529e-15 (rank : 22)	NC score	0.691896 (rank : 40)
Query Neighborhood Hits	105	Target Neighborhood Hits	432	Shared Neighborhood Hits	62
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

STAR8_HUMAN
θ value	1.99529e-15 (rank : 23)	NC score	0.692564 (rank : 39)
Query Neighborhood Hits	105	Target Neighborhood Hits	216	Shared Neighborhood Hits	60
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RHG08_HUMAN
θ value	3.40345e-15 (rank : 24)	NC score	0.766948 (rank : 16)
Query Neighborhood Hits	105	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG25_MOUSE
θ value	3.40345e-15 (rank : 25)	NC score	0.718816 (rank : 27)
Query Neighborhood Hits	105	Target Neighborhood Hits	492	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
θ value	4.44505e-15 (rank : 26)	NC score	0.696100 (rank : 37)
Query Neighborhood Hits	105	Target Neighborhood Hits	550	Shared Neighborhood Hits	61
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG04_HUMAN
θ value	5.8054e-15 (rank : 27)	NC score	0.719302 (rank : 26)
Query Neighborhood Hits	105	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

STA13_MOUSE
θ value	7.58209e-15 (rank : 28)	NC score	0.686960 (rank : 46)
Query Neighborhood Hits	105	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

RBP1_MOUSE
θ value	9.90251e-15 (rank : 29)	NC score	0.714127 (rank : 31)
Query Neighborhood Hits	105	Target Neighborhood Hits	493	Shared Neighborhood Hits	61
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

TCGAP_HUMAN
θ value	1.68911e-14 (rank : 30)	NC score	0.655044 (rank : 47)
Query Neighborhood Hits	105	Target Neighborhood Hits	872	Shared Neighborhood Hits	66
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

STA13_HUMAN
θ value	4.91457e-14 (rank : 31)	NC score	0.691220 (rank : 42)
Query Neighborhood Hits	105	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

TCGAP_MOUSE
θ value	4.91457e-14 (rank : 32)	NC score	0.737563 (rank : 20)
Query Neighborhood Hits	105	Target Neighborhood Hits	409	Shared Neighborhood Hits	64
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BCR_HUMAN
θ value	6.41864e-14 (rank : 33)	NC score	0.691886 (rank : 41)
Query Neighborhood Hits	105	Target Neighborhood Hits	204	Shared Neighborhood Hits	63
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG26_HUMAN
θ value	8.38298e-14 (rank : 34)	NC score	0.688131 (rank : 44)
Query Neighborhood Hits	105	Target Neighborhood Hits	281	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RGAP1_HUMAN
θ value	1.09485e-13 (rank : 35)	NC score	0.777077 (rank : 11)
Query Neighborhood Hits	105	Target Neighborhood Hits	189	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

GMIP_HUMAN
θ value	1.86753e-13 (rank : 36)	NC score	0.777554 (rank : 10)
Query Neighborhood Hits	105	Target Neighborhood Hits	225	Shared Neighborhood Hits	62
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

SRGP1_HUMAN
θ value	1.86753e-13 (rank : 37)	NC score	0.688093 (rank : 45)
Query Neighborhood Hits	105	Target Neighborhood Hits	390	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

CEND3_MOUSE
θ value	3.18553e-13 (rank : 38)	NC score	0.597523 (rank : 51)
Query Neighborhood Hits	105	Target Neighborhood Hits	228	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CE005_MOUSE
θ value	4.16044e-13 (rank : 39)	NC score	0.641301 (rank : 49)
Query Neighborhood Hits	105	Target Neighborhood Hits	238	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

RBP1_HUMAN
θ value	5.43371e-13 (rank : 40)	NC score	0.690464 (rank : 43)
Query Neighborhood Hits	105	Target Neighborhood Hits	521	Shared Neighborhood Hits	61
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

CE005_HUMAN
θ value	7.09661e-13 (rank : 41)	NC score	0.643456 (rank : 48)
Query Neighborhood Hits	105	Target Neighborhood Hits	213	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CEND3_HUMAN
θ value	1.2105e-12 (rank : 42)	NC score	0.586293 (rank : 52)
Query Neighborhood Hits	105	Target Neighborhood Hits	275	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

TAGAP_HUMAN
θ value	1.2105e-12 (rank : 43)	NC score	0.733118 (rank : 22)
Query Neighborhood Hits	105	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RGAP1_MOUSE
θ value	2.0648e-12 (rank : 44)	NC score	0.768111 (rank : 15)
Query Neighborhood Hits	105	Target Neighborhood Hits	185	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG18_HUMAN
θ value	2.69671e-12 (rank : 45)	NC score	0.776791 (rank : 12)
Query Neighborhood Hits	105	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
θ value	4.59992e-12 (rank : 46)	NC score	0.774371 (rank : 13)
Query Neighborhood Hits	105	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

TAGAP_MOUSE
θ value	7.84624e-12 (rank : 47)	NC score	0.731045 (rank : 23)
Query Neighborhood Hits	105	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

CEND2_HUMAN
θ value	2.28291e-11 (rank : 48)	NC score	0.623310 (rank : 50)
Query Neighborhood Hits	105	Target Neighborhood Hits	166	Shared Neighborhood Hits	61
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

GRLF1_HUMAN
θ value	3.89403e-11 (rank : 49)	NC score	0.743083 (rank : 18)
Query Neighborhood Hits	105	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG09_HUMAN
θ value	5.08577e-11 (rank : 50)	NC score	0.787302 (rank : 7)
Query Neighborhood Hits	105	Target Neighborhood Hits	186	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

CEND1_HUMAN
θ value	6.64225e-11 (rank : 51)	NC score	0.513040 (rank : 56)
Query Neighborhood Hits	105	Target Neighborhood Hits	284	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CEND1_MOUSE
θ value	1.133e-10 (rank : 52)	NC score	0.531863 (rank : 55)
Query Neighborhood Hits	105	Target Neighborhood Hits	260	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

OPHN1_MOUSE
θ value	2.52405e-10 (rank : 53)	NC score	0.716966 (rank : 29)
Query Neighborhood Hits	105	Target Neighborhood Hits	174	Shared Neighborhood Hits	62
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RHG05_MOUSE
θ value	4.30538e-10 (rank : 54)	NC score	0.706365 (rank : 35)
Query Neighborhood Hits	105	Target Neighborhood Hits	165	Shared Neighborhood Hits	62
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

OPHN1_HUMAN
θ value	1.25267e-09 (rank : 55)	NC score	0.715663 (rank : 30)
Query Neighborhood Hits	105	Target Neighborhood Hits	161	Shared Neighborhood Hits	63
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

RHG05_HUMAN
θ value	8.11959e-09 (rank : 56)	NC score	0.692908 (rank : 38)
Query Neighborhood Hits	105	Target Neighborhood Hits	158	Shared Neighborhood Hits	62
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

K1688_HUMAN
θ value	2.88788e-06 (rank : 57)	NC score	0.543760 (rank : 54)
Query Neighborhood Hits	105	Target Neighborhood Hits	217	Shared Neighborhood Hits	59
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

K1688_MOUSE
θ value	2.88788e-06 (rank : 58)	NC score	0.556398 (rank : 53)
Query Neighborhood Hits	105	Target Neighborhood Hits	188	Shared Neighborhood Hits	60
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

OCRL_HUMAN
θ value	1.43324e-05 (rank : 59)	NC score	0.340490 (rank : 60)
Query Neighborhood Hits	105	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

P85A_HUMAN
θ value	0.00175202 (rank : 60)	NC score	0.346551 (rank : 59)
Query Neighborhood Hits	105	Target Neighborhood Hits	479	Shared Neighborhood Hits	59
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
θ value	0.0563607 (rank : 61)	NC score	0.331914 (rank : 62)
Query Neighborhood Hits	105	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

P85A_MOUSE
θ value	0.125558 (rank : 62)	NC score	0.332038 (rank : 61)
Query Neighborhood Hits	105	Target Neighborhood Hits	435	Shared Neighborhood Hits	59
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

DYDC2_HUMAN
θ value	0.163984 (rank : 63)	NC score	0.077198 (rank : 65)
Query Neighborhood Hits	105	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IM9, Q5QP07, Q5QP11	Gene names	DYDC2
Domain Architecture	No domain graphic available
Description	DPY30 domain-containing protein 2.

DCR1A_MOUSE
θ value	0.279714 (rank : 64)	NC score	0.041586 (rank : 100)
Query Neighborhood Hits	105	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

ULK1_HUMAN
θ value	0.365318 (rank : 65)	NC score	0.000427 (rank : 136)
Query Neighborhood Hits	105	Target Neighborhood Hits	1121	Shared Neighborhood Hits	10
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

CD2L7_HUMAN
θ value	0.47712 (rank : 66)	NC score	0.002061 (rank : 131)
Query Neighborhood Hits	105	Target Neighborhood Hits	1275	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

GBP5_MOUSE
θ value	0.47712 (rank : 67)	NC score	0.014992 (rank : 112)
Query Neighborhood Hits	105	Target Neighborhood Hits	254	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFB4, Q8CFA4	Gene names	Gbp5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (MuGBP-5).

KAP1_HUMAN
θ value	0.47712 (rank : 68)	NC score	0.027788 (rank : 103)
Query Neighborhood Hits	105	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

CU030_HUMAN
θ value	0.62314 (rank : 69)	NC score	0.041819 (rank : 99)
Query Neighborhood Hits	105	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UFM2	Gene names	C21orf30
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf30.

DZIP1_HUMAN
θ value	0.62314 (rank : 70)	NC score	0.018067 (rank : 109)
Query Neighborhood Hits	105	Target Neighborhood Hits	675	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

HSP74_MOUSE
θ value	0.62314 (rank : 71)	NC score	0.010397 (rank : 119)
Query Neighborhood Hits	105	Target Neighborhood Hits	257	Shared Neighborhood Hits	4
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

JHD2B_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.018280 (rank : 108)
Query Neighborhood Hits	105	Target Neighborhood Hits	171	Shared Neighborhood Hits	4
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

K1219_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.029635 (rank : 102)
Query Neighborhood Hits	105	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

PMS2_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.022898 (rank : 104)
Query Neighborhood Hits	105	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

ZBTB8_MOUSE
θ value	1.38821 (rank : 75)	NC score	-0.001957 (rank : 140)
Query Neighborhood Hits	105	Target Neighborhood Hits	791	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CII0	Gene names	Zbtb8
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 8.

HNF4A_MOUSE
θ value	1.81305 (rank : 76)	NC score	0.004777 (rank : 128)
Query Neighborhood Hits	105	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

TCOF_MOUSE
θ value	1.81305 (rank : 77)	NC score	0.018350 (rank : 107)
Query Neighborhood Hits	105	Target Neighborhood Hits	471	Shared Neighborhood Hits	11
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

KAP1_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.021262 (rank : 106)
Query Neighborhood Hits	105	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

MGRN1_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.014316 (rank : 113)
Query Neighborhood Hits	105	Target Neighborhood Hits	192	Shared Neighborhood Hits	2
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

NPAS4_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.015819 (rank : 110)
Query Neighborhood Hits	105	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

ZSCA1_HUMAN
θ value	2.36792 (rank : 81)	NC score	-0.000435 (rank : 138)
Query Neighborhood Hits	105	Target Neighborhood Hits	724	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NBB4, Q6WLH8, Q86WS8	Gene names	ZSCAN1
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 1.

TREF1_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.015693 (rank : 111)
Query Neighborhood Hits	105	Target Neighborhood Hits	682	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

ULK1_MOUSE
θ value	3.0926 (rank : 83)	NC score	0.000748 (rank : 135)
Query Neighborhood Hits	105	Target Neighborhood Hits	1214	Shared Neighborhood Hits	9
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

MYST4_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.006713 (rank : 125)
Query Neighborhood Hits	105	Target Neighborhood Hits	671	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

UBP43_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.007928 (rank : 123)
Query Neighborhood Hits	105	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

CCNT1_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.008575 (rank : 121)
Query Neighborhood Hits	105	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	O60563, O60581	Gene names	CCNT1
Domain Architecture
Description	Cyclin-T1 (CycT1) (Cyclin-T).

CHX10_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.000419 (rank : 137)
Query Neighborhood Hits	105	Target Neighborhood Hits	340	Shared Neighborhood Hits	2
SwissProt Accessions	P58304	Gene names	CHX10, VSX2
Domain Architecture
Description	Homeobox protein CHX10 (Ceh-10 homeodomain-containing homolog).

GNRP_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.037431 (rank : 101)
Query Neighborhood Hits	105	Target Neighborhood Hits	239	Shared Neighborhood Hits	9
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

MEFV_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.001430 (rank : 133)
Query Neighborhood Hits	105	Target Neighborhood Hits	431	Shared Neighborhood Hits	4
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

NC6IP_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.010224 (rank : 120)
Query Neighborhood Hits	105	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	Q923W1, Q6DI60, Q6PEA7, Q8R0W9	Gene names	Ncoa6ip, Pimt
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT).

UNG_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.014062 (rank : 114)
Query Neighborhood Hits	105	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P97931, P97285, P97509, Q7TPW8	Gene names	Ung
Domain Architecture
Description	Uracil-DNA glycosylase (UDG).

AMOT_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.001321 (rank : 134)
Query Neighborhood Hits	105	Target Neighborhood Hits	712	Shared Neighborhood Hits	4
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

DACT1_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.010710 (rank : 118)
Query Neighborhood Hits	105	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

DGC14_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.012792 (rank : 116)
Query Neighborhood Hits	105	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DF8, Q9BTZ4	Gene names	DGCR14, DGSI, ES2
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14) (ES2 protein).

ES8L1_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.011750 (rank : 117)
Query Neighborhood Hits	105	Target Neighborhood Hits	143	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

MPP2_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.008226 (rank : 122)
Query Neighborhood Hits	105	Target Neighborhood Hits	173	Shared Neighborhood Hits	6
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

NPAS4_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.013186 (rank : 115)
Query Neighborhood Hits	105	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

RNAS2_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.007514 (rank : 124)
Query Neighborhood Hits	105	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P10153, Q9H2B7, Q9UCG7	Gene names	RNASE2, EDN, RNS2
Domain Architecture
Description	Nonsecretory ribonuclease precursor (EC 3.1.27.5) (Ribonuclease US) (Eosinophil-derived neurotoxin) (RNase UpI-2) (Ribonuclease 2) (RNase 2).

WNK2_HUMAN
θ value	6.88961 (rank : 99)	NC score	-0.000673 (rank : 139)
Query Neighborhood Hits	105	Target Neighborhood Hits	1407	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZO2_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.006529 (rank : 126)
Query Neighborhood Hits	105	Target Neighborhood Hits	289	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

CNTP4_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.001548 (rank : 132)
Query Neighborhood Hits	105	Target Neighborhood Hits	193	Shared Neighborhood Hits	2
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

HNF4A_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.002793 (rank : 129)
Query Neighborhood Hits	105	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

K1543_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.021881 (rank : 105)
Query Neighborhood Hits	105	Target Neighborhood Hits	497	Shared Neighborhood Hits	11
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

RP1L1_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.005741 (rank : 127)
Query Neighborhood Hits	105	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

SFRS7_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.002757 (rank : 130)
Query Neighborhood Hits	105	Target Neighborhood Hits	191	Shared Neighborhood Hits	2
SwissProt Accessions	Q16629	Gene names	SFRS7
Domain Architecture
Description	Splicing factor, arginine/serine-rich 7 (Splicing factor 9G8).

ATCAY_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.060422 (rank : 76)
Query Neighborhood Hits	105	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

ATCAY_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.061189 (rank : 75)
Query Neighborhood Hits	105	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

BNIP2_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.064155 (rank : 73)
Query Neighborhood Hits	105	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.064024 (rank : 74)
Query Neighborhood Hits	105	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIPL_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.059454 (rank : 77)
Query Neighborhood Hits	105	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

BNIPL_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.059262 (rank : 78)
Query Neighborhood Hits	105	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JU7, Q923E3	Gene names	Bnipl
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

CENA1_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.051964 (rank : 92)
Query Neighborhood Hits	105	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.056280 (rank : 83)
Query Neighborhood Hits	105	Target Neighborhood Hits	83	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.068668 (rank : 71)
Query Neighborhood Hits	105	Target Neighborhood Hits	383	Shared Neighborhood Hits	11
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.073613 (rank : 70)
Query Neighborhood Hits	105	Target Neighborhood Hits	425	Shared Neighborhood Hits	13
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.068047 (rank : 72)
Query Neighborhood Hits	105	Target Neighborhood Hits	395	Shared Neighborhood Hits	9
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CIP4_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.056680 (rank : 82)
Query Neighborhood Hits	105	Target Neighborhood Hits	374	Shared Neighborhood Hits	9
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

DDEF2_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.053076 (rank : 88)
Query Neighborhood Hits	105	Target Neighborhood Hits	599	Shared Neighborhood Hits	13
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.052449 (rank : 91)
Query Neighborhood Hits	105	Target Neighborhood Hits	625	Shared Neighborhood Hits	13
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.051669 (rank : 93)
Query Neighborhood Hits	105	Target Neighborhood Hits	353	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

FA13A_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.073933 (rank : 69)
Query Neighborhood Hits	105	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.075376 (rank : 67)
Query Neighborhood Hits	105	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

FA13C_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.058358 (rank : 79)
Query Neighborhood Hits	105	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

FA13C_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.057043 (rank : 81)
Query Neighborhood Hits	105	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GRAP_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.052928 (rank : 90)
Query Neighborhood Hits	105	Target Neighborhood Hits	307	Shared Neighborhood Hits	15
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.050251 (rank : 97)
Query Neighborhood Hits	105	Target Neighborhood Hits	310	Shared Neighborhood Hits	15
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.050248 (rank : 98)
Query Neighborhood Hits	105	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRP3_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.074060 (rank : 68)
Query Neighborhood Hits	105	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

NCK2_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.057998 (rank : 80)
Query Neighborhood Hits	105	Target Neighborhood Hits	310	Shared Neighborhood Hits	16
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

P85B_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.077110 (rank : 66)
Query Neighborhood Hits	105	Target Neighborhood Hits	543	Shared Neighborhood Hits	24
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.051376 (rank : 95)
Query Neighborhood Hits	105	Target Neighborhood Hits	519	Shared Neighborhood Hits	20
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PCTL_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.083454 (rank : 64)
Query Neighborhood Hits	105	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PCTL_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.084402 (rank : 63)
Query Neighborhood Hits	105	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PDZD8_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.051594 (rank : 94)
Query Neighborhood Hits	105	Target Neighborhood Hits	185	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PKHA1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.053820 (rank : 86)
Query Neighborhood Hits	105	Target Neighborhood Hits	127	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

SMAP1_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.053137 (rank : 87)
Query Neighborhood Hits	105	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.052970 (rank : 89)
Query Neighborhood Hits	105	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.054653 (rank : 84)
Query Neighborhood Hits	105	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.054577 (rank : 85)
Query Neighborhood Hits	105	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

VINEX_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.050595 (rank : 96)
Query Neighborhood Hits	105	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

Hits sorted by NC score

RHG06_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	105	Target Neighborhood Hits	105	Shared Neighborhood Hits	105
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_HUMAN
NC score	0.994230 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	105	Target Neighborhood Hits	114	Shared Neighborhood Hits	73
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

3BP1_MOUSE
NC score	0.809594 (rank : 3)	θ value	4.74913e-17 (rank : 12)
Query Neighborhood Hits	105	Target Neighborhood Hits	238	Shared Neighborhood Hits	63
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG01_HUMAN
NC score	0.797782 (rank : 4)	θ value	7.82807e-20 (rank : 4)
Query Neighborhood Hits	105	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

3BP1_HUMAN
NC score	0.789350 (rank : 5)	θ value	1.92812e-18 (rank : 8)
Query Neighborhood Hits	105	Target Neighborhood Hits	376	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

GMIP_MOUSE
NC score	0.788944 (rank : 6)	θ value	4.02038e-16 (rank : 15)
Query Neighborhood Hits	105	Target Neighborhood Hits	202	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG09_HUMAN
NC score	0.787302 (rank : 7)	θ value	5.08577e-11 (rank : 50)
Query Neighborhood Hits	105	Target Neighborhood Hits	186	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG12_HUMAN
NC score	0.783382 (rank : 8)	θ value	2.13179e-17 (rank : 11)
Query Neighborhood Hits	105	Target Neighborhood Hits	190	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
NC score	0.781099 (rank : 9)	θ value	4.74913e-17 (rank : 13)
Query Neighborhood Hits	105	Target Neighborhood Hits	204	Shared Neighborhood Hits	63
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

GMIP_HUMAN
NC score	0.777554 (rank : 10)	θ value	1.86753e-13 (rank : 36)
Query Neighborhood Hits	105	Target Neighborhood Hits	225	Shared Neighborhood Hits	62
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RGAP1_HUMAN
NC score	0.777077 (rank : 11)	θ value	1.09485e-13 (rank : 35)
Query Neighborhood Hits	105	Target Neighborhood Hits	189	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG18_HUMAN
NC score	0.776791 (rank : 12)	θ value	2.69671e-12 (rank : 45)
Query Neighborhood Hits	105	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
NC score	0.774371 (rank : 13)	θ value	4.59992e-12 (rank : 46)
Query Neighborhood Hits	105	Target Neighborhood Hits	110	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG08_MOUSE
NC score	0.771257 (rank : 14)	θ value	1.16975e-15 (rank : 20)
Query Neighborhood Hits	105	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RGAP1_MOUSE
NC score	0.768111 (rank : 15)	θ value	2.0648e-12 (rank : 44)
Query Neighborhood Hits	105	Target Neighborhood Hits	185	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG08_HUMAN
NC score	0.766948 (rank : 16)	θ value	3.40345e-15 (rank : 24)
Query Neighborhood Hits	105	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

CHIO_MOUSE
NC score	0.744307 (rank : 17)	θ value	1.16975e-15 (rank : 19)
Query Neighborhood Hits	105	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

GRLF1_HUMAN
NC score	0.743083 (rank : 18)	θ value	3.89403e-11 (rank : 49)
Query Neighborhood Hits	105	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG07_MOUSE
NC score	0.738103 (rank : 19)	θ value	1.63225e-17 (rank : 10)
Query Neighborhood Hits	105	Target Neighborhood Hits	103	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

TCGAP_MOUSE
NC score	0.737563 (rank : 20)	θ value	4.91457e-14 (rank : 32)
Query Neighborhood Hits	105	Target Neighborhood Hits	409	Shared Neighborhood Hits	64
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG07_HUMAN
NC score	0.735516 (rank : 21)	θ value	3.28887e-18 (rank : 9)
Query Neighborhood Hits	105	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

TAGAP_HUMAN
NC score	0.733118 (rank : 22)	θ value	1.2105e-12 (rank : 43)
Query Neighborhood Hits	105	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_MOUSE
NC score	0.731045 (rank : 23)	θ value	7.84624e-12 (rank : 47)
Query Neighborhood Hits	105	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

CHIN_MOUSE
NC score	0.720867 (rank : 24)	θ value	8.65492e-19 (rank : 7)
Query Neighborhood Hits	105	Target Neighborhood Hits	229	Shared Neighborhood Hits	62
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_HUMAN
NC score	0.719910 (rank : 25)	θ value	1.33526e-19 (rank : 5)
Query Neighborhood Hits	105	Target Neighborhood Hits	227	Shared Neighborhood Hits	61
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG04_HUMAN
NC score	0.719302 (rank : 26)	θ value	5.8054e-15 (rank : 27)
Query Neighborhood Hits	105	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG25_MOUSE
NC score	0.718816 (rank : 27)	θ value	3.40345e-15 (rank : 25)
Query Neighborhood Hits	105	Target Neighborhood Hits	492	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SRGP2_HUMAN
NC score	0.718445 (rank : 28)	θ value	3.51386e-20 (rank : 3)
Query Neighborhood Hits	105	Target Neighborhood Hits	331	Shared Neighborhood Hits	64
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

OPHN1_MOUSE
NC score	0.716966 (rank : 29)	θ value	2.52405e-10 (rank : 53)
Query Neighborhood Hits	105	Target Neighborhood Hits	174	Shared Neighborhood Hits	62
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_HUMAN
NC score	0.715663 (rank : 30)	θ value	1.25267e-09 (rank : 55)
Query Neighborhood Hits	105	Target Neighborhood Hits	161	Shared Neighborhood Hits	63
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

RBP1_MOUSE
NC score	0.714127 (rank : 31)	θ value	9.90251e-15 (rank : 29)
Query Neighborhood Hits	105	Target Neighborhood Hits	493	Shared Neighborhood Hits	61
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

CHIO_HUMAN
NC score	0.712451 (rank : 32)	θ value	1.52774e-15 (rank : 21)
Query Neighborhood Hits	105	Target Neighborhood Hits	220	Shared Neighborhood Hits	61
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

ABR_HUMAN
NC score	0.709969 (rank : 33)	θ value	5.25075e-16 (rank : 16)
Query Neighborhood Hits	105	Target Neighborhood Hits	166	Shared Neighborhood Hits	63
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

SRGP2_MOUSE
NC score	0.709881 (rank : 34)	θ value	3.88503e-19 (rank : 6)
Query Neighborhood Hits	105	Target Neighborhood Hits	324	Shared Neighborhood Hits	63
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG05_MOUSE
NC score	0.706365 (rank : 35)	θ value	4.30538e-10 (rank : 54)
Query Neighborhood Hits	105	Target Neighborhood Hits	165	Shared Neighborhood Hits	62
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

STAR8_MOUSE
NC score	0.704521 (rank : 36)	θ value	1.80466e-16 (rank : 14)
Query Neighborhood Hits	105	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RHG25_HUMAN
NC score	0.696100 (rank : 37)	θ value	4.44505e-15 (rank : 26)
Query Neighborhood Hits	105	Target Neighborhood Hits	550	Shared Neighborhood Hits	61
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG05_HUMAN
NC score	0.692908 (rank : 38)	θ value	8.11959e-09 (rank : 56)
Query Neighborhood Hits	105	Target Neighborhood Hits	158	Shared Neighborhood Hits	62
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

STAR8_HUMAN
NC score	0.692564 (rank : 39)	θ value	1.99529e-15 (rank : 23)
Query Neighborhood Hits	105	Target Neighborhood Hits	216	Shared Neighborhood Hits	60
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

FNBP2_HUMAN
NC score	0.691896 (rank : 40)	θ value	1.99529e-15 (rank : 22)
Query Neighborhood Hits	105	Target Neighborhood Hits	432	Shared Neighborhood Hits	62
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

BCR_HUMAN
NC score	0.691886 (rank : 41)	θ value	6.41864e-14 (rank : 33)
Query Neighborhood Hits	105	Target Neighborhood Hits	204	Shared Neighborhood Hits	63
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

STA13_HUMAN
NC score	0.691220 (rank : 42)	θ value	4.91457e-14 (rank : 31)
Query Neighborhood Hits	105	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

RBP1_HUMAN
NC score	0.690464 (rank : 43)	θ value	5.43371e-13 (rank : 40)
Query Neighborhood Hits	105	Target Neighborhood Hits	521	Shared Neighborhood Hits	61
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG26_HUMAN
NC score	0.688131 (rank : 44)	θ value	8.38298e-14 (rank : 34)
Query Neighborhood Hits	105	Target Neighborhood Hits	281	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

SRGP1_HUMAN
NC score	0.688093 (rank : 45)	θ value	1.86753e-13 (rank : 37)
Query Neighborhood Hits	105	Target Neighborhood Hits	390	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

STA13_MOUSE
NC score	0.686960 (rank : 46)	θ value	7.58209e-15 (rank : 28)
Query Neighborhood Hits	105	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

TCGAP_HUMAN
NC score	0.655044 (rank : 47)	θ value	1.68911e-14 (rank : 30)
Query Neighborhood Hits	105	Target Neighborhood Hits	872	Shared Neighborhood Hits	66
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CE005_HUMAN
NC score	0.643456 (rank : 48)	θ value	7.09661e-13 (rank : 41)
Query Neighborhood Hits	105	Target Neighborhood Hits	213	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
NC score	0.641301 (rank : 49)	θ value	4.16044e-13 (rank : 39)
Query Neighborhood Hits	105	Target Neighborhood Hits	238	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CEND2_HUMAN
NC score	0.623310 (rank : 50)	θ value	2.28291e-11 (rank : 48)
Query Neighborhood Hits	105	Target Neighborhood Hits	166	Shared Neighborhood Hits	61
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CEND3_MOUSE
NC score	0.597523 (rank : 51)	θ value	3.18553e-13 (rank : 38)
Query Neighborhood Hits	105	Target Neighborhood Hits	228	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND3_HUMAN
NC score	0.586293 (rank : 52)	θ value	1.2105e-12 (rank : 42)
Query Neighborhood Hits	105	Target Neighborhood Hits	275	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

K1688_MOUSE
NC score	0.556398 (rank : 53)	θ value	2.88788e-06 (rank : 58)
Query Neighborhood Hits	105	Target Neighborhood Hits	188	Shared Neighborhood Hits	60
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
NC score	0.543760 (rank : 54)	θ value	2.88788e-06 (rank : 57)
Query Neighborhood Hits	105	Target Neighborhood Hits	217	Shared Neighborhood Hits	59
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CEND1_MOUSE
NC score	0.531863 (rank : 55)	θ value	1.133e-10 (rank : 52)
Query Neighborhood Hits	105	Target Neighborhood Hits	260	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.513040 (rank : 56)	θ value	6.64225e-11 (rank : 51)
Query Neighborhood Hits	105	Target Neighborhood Hits	284	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

MYO9B_MOUSE
NC score	0.413391 (rank : 57)	θ value	6.85773e-16 (rank : 18)
Query Neighborhood Hits	105	Target Neighborhood Hits	311	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.407908 (rank : 58)	θ value	5.25075e-16 (rank : 17)
Query Neighborhood Hits	105	Target Neighborhood Hits	641	Shared Neighborhood Hits	68
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_HUMAN
NC score	0.346551 (rank : 59)	θ value	0.00175202 (rank : 60)
Query Neighborhood Hits	105	Target Neighborhood Hits	479	Shared Neighborhood Hits	59
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

OCRL_HUMAN
NC score	0.340490 (rank : 60)	θ value	1.43324e-05 (rank : 59)
Query Neighborhood Hits	105	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

P85A_MOUSE
NC score	0.332038 (rank : 61)	θ value	0.125558 (rank : 62)
Query Neighborhood Hits	105	Target Neighborhood Hits	435	Shared Neighborhood Hits	59
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
NC score	0.331914 (rank : 62)	θ value	0.0563607 (rank : 61)
Query Neighborhood Hits	105	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

PCTL_MOUSE
NC score	0.084402 (rank : 63)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	105	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PCTL_HUMAN
NC score	0.083454 (rank : 64)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	105	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

DYDC2_HUMAN
NC score	0.077198 (rank : 65)	θ value	0.163984 (rank : 63)
Query Neighborhood Hits	105	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IM9, Q5QP07, Q5QP11	Gene names	DYDC2
Domain Architecture	No domain graphic available
Description	DPY30 domain-containing protein 2.

P85B_HUMAN
NC score	0.077110 (rank : 66)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	105	Target Neighborhood Hits	543	Shared Neighborhood Hits	24
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

FA13A_MOUSE
NC score	0.075376 (rank : 67)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	105	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

GRP3_HUMAN
NC score	0.074060 (rank : 68)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	105	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

FA13A_HUMAN
NC score	0.073933 (rank : 69)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	105	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

CENB2_HUMAN
NC score	0.073613 (rank : 70)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	105	Target Neighborhood Hits	425	Shared Neighborhood Hits	13
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB1_HUMAN
NC score	0.068668 (rank : 71)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	105	Target Neighborhood Hits	383	Shared Neighborhood Hits	11
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB5_HUMAN
NC score	0.068047 (rank : 72)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	105	Target Neighborhood Hits	395	Shared Neighborhood Hits	9
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

BNIP2_HUMAN
NC score	0.064155 (rank : 73)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	105	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
NC score	0.064024 (rank : 74)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	105	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

ATCAY_MOUSE
NC score	0.061189 (rank : 75)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	105	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

ATCAY_HUMAN
NC score	0.060422 (rank : 76)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	105	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

BNIPL_HUMAN
NC score	0.059454 (rank : 77)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	105	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

BNIPL_MOUSE
NC score	0.059262 (rank : 78)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	105	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JU7, Q923E3	Gene names	Bnipl
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

FA13C_HUMAN
NC score	0.058358 (rank : 79)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	105	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NE31, Q99787	Gene names	FAM13C1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

NCK2_HUMAN
NC score	0.057998 (rank : 80)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	105	Target Neighborhood Hits	310	Shared Neighborhood Hits	16
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

FA13C_MOUSE
NC score	0.057043 (rank : 81)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	105	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

CIP4_HUMAN
NC score	0.056680 (rank : 82)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	105	Target Neighborhood Hits	374	Shared Neighborhood Hits	9
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CENA2_HUMAN
NC score	0.056280 (rank : 83)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	105	Target Neighborhood Hits	83	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

SMP1L_HUMAN
NC score	0.054653 (rank : 84)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	105	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
NC score	0.054577 (rank : 85)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	105	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

PKHA1_HUMAN
NC score	0.053820 (rank : 86)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	105	Target Neighborhood Hits	127	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

SMAP1_HUMAN
NC score	0.053137 (rank : 87)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	105	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

DDEF2_HUMAN
NC score	0.053076 (rank : 88)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	105	Target Neighborhood Hits	599	Shared Neighborhood Hits	13
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SMAP1_MOUSE
NC score	0.052970 (rank : 89)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	105	Target Neighborhood Hits	120	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

GRAP_HUMAN
NC score	0.052928 (rank : 90)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	105	Target Neighborhood Hits	307	Shared Neighborhood Hits	15
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

DDEF2_MOUSE
NC score	0.052449 (rank : 91)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	105	Target Neighborhood Hits	625	Shared Neighborhood Hits	13
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

CENA1_HUMAN
NC score	0.051964 (rank : 92)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	105	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

DDFL1_HUMAN
NC score	0.051669 (rank : 93)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	105	Target Neighborhood Hits	353	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

PDZD8_HUMAN
NC score	0.051594 (rank : 94)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	105	Target Neighborhood Hits	185	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

P85B_MOUSE
NC score	0.051376 (rank : 95)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	105	Target Neighborhood Hits	519	Shared Neighborhood Hits	20
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

VINEX_MOUSE
NC score	0.050595 (rank : 96)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	105	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

GRB2_HUMAN
NC score	0.050251 (rank : 97)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	105	Target Neighborhood Hits	310	Shared Neighborhood Hits	15
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.050248 (rank : 98)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	105	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

CU030_HUMAN
NC score	0.041819 (rank : 99)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	105	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UFM2	Gene names	C21orf30
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf30.

DCR1A_MOUSE
NC score	0.041586 (rank : 100)	θ value	0.279714 (rank : 64)
Query Neighborhood Hits	105	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

GNRP_HUMAN
NC score	0.037431 (rank : 101)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	105	Target Neighborhood Hits	239	Shared Neighborhood Hits	9
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

K1219_HUMAN
NC score	0.029635 (rank : 102)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	105	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

KAP1_HUMAN
NC score	0.027788 (rank : 103)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	105	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

PMS2_HUMAN
NC score	0.022898 (rank : 104)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	105	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

K1543_MOUSE
NC score	0.021881 (rank : 105)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	105	Target Neighborhood Hits	497	Shared Neighborhood Hits	11
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

KAP1_MOUSE
NC score	0.021262 (rank : 106)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	105	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

TCOF_MOUSE
NC score	0.018350 (rank : 107)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	105	Target Neighborhood Hits	471	Shared Neighborhood Hits	11
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

JHD2B_HUMAN
NC score	0.018280 (rank : 108)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	105	Target Neighborhood Hits	171	Shared Neighborhood Hits	4
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

DZIP1_HUMAN
NC score	0.018067 (rank : 109)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	105	Target Neighborhood Hits	675	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

NPAS4_HUMAN
NC score	0.015819 (rank : 110)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	105	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

TREF1_MOUSE
NC score	0.015693 (rank : 111)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	105	Target Neighborhood Hits	682	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

GBP5_MOUSE
NC score	0.014992 (rank : 112)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	105	Target Neighborhood Hits	254	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFB4, Q8CFA4	Gene names	Gbp5
Domain Architecture
Description	Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-5) (MuGBP-5).

MGRN1_HUMAN
NC score	0.014316 (rank : 113)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	105	Target Neighborhood Hits	192	Shared Neighborhood Hits	2
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

UNG_MOUSE
NC score	0.014062 (rank : 114)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	105	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P97931, P97285, P97509, Q7TPW8	Gene names	Ung
Domain Architecture
Description	Uracil-DNA glycosylase (UDG).

NPAS4_MOUSE
NC score	0.013186 (rank : 115)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	105	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

DGC14_HUMAN
NC score	0.012792 (rank : 116)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	105	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DF8, Q9BTZ4	Gene names	DGCR14, DGSI, ES2
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14) (ES2 protein).

ES8L1_MOUSE
NC score	0.011750 (rank : 117)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	105	Target Neighborhood Hits	143	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

DACT1_HUMAN
NC score	0.010710 (rank : 118)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	105	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

HSP74_MOUSE
NC score	0.010397 (rank : 119)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	105	Target Neighborhood Hits	257	Shared Neighborhood Hits	4
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

NC6IP_MOUSE
NC score	0.010224 (rank : 120)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	105	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	Q923W1, Q6DI60, Q6PEA7, Q8R0W9	Gene names	Ncoa6ip, Pimt
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT).

CCNT1_HUMAN
NC score	0.008575 (rank : 121)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	105	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	O60563, O60581	Gene names	CCNT1
Domain Architecture
Description	Cyclin-T1 (CycT1) (Cyclin-T).

MPP2_HUMAN
NC score	0.008226 (rank : 122)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	105	Target Neighborhood Hits	173	Shared Neighborhood Hits	6
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

UBP43_HUMAN
NC score	0.007928 (rank : 123)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	105	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

RNAS2_HUMAN
NC score	0.007514 (rank : 124)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	105	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P10153, Q9H2B7, Q9UCG7	Gene names	RNASE2, EDN, RNS2
Domain Architecture
Description	Nonsecretory ribonuclease precursor (EC 3.1.27.5) (Ribonuclease US) (Eosinophil-derived neurotoxin) (RNase UpI-2) (Ribonuclease 2) (RNase 2).

MYST4_HUMAN
NC score	0.006713 (rank : 125)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	105	Target Neighborhood Hits	671	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

ZO2_HUMAN
NC score	0.006529 (rank : 126)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	105	Target Neighborhood Hits	289	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

RP1L1_MOUSE
NC score	0.005741 (rank : 127)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	105	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

HNF4A_MOUSE
NC score	0.004777 (rank : 128)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	105	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4A_HUMAN
NC score	0.002793 (rank : 129)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	105	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

SFRS7_HUMAN
NC score	0.002757 (rank : 130)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	105	Target Neighborhood Hits	191	Shared Neighborhood Hits	2
SwissProt Accessions	Q16629	Gene names	SFRS7
Domain Architecture
Description	Splicing factor, arginine/serine-rich 7 (Splicing factor 9G8).

CD2L7_HUMAN
NC score	0.002061 (rank : 131)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	105	Target Neighborhood Hits	1275	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CNTP4_MOUSE
NC score	0.001548 (rank : 132)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	105	Target Neighborhood Hits	193	Shared Neighborhood Hits	2
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

MEFV_HUMAN
NC score	0.001430 (rank : 133)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	105	Target Neighborhood Hits	431	Shared Neighborhood Hits	4
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

AMOT_HUMAN
NC score	0.001321 (rank : 134)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	105	Target Neighborhood Hits	712	Shared Neighborhood Hits	4
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

ULK1_MOUSE
NC score	0.000748 (rank : 135)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	105	Target Neighborhood Hits	1214	Shared Neighborhood Hits	9
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ULK1_HUMAN
NC score	0.000427 (rank : 136)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	105	Target Neighborhood Hits	1121	Shared Neighborhood Hits	10
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

CHX10_HUMAN
NC score	0.000419 (rank : 137)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	105	Target Neighborhood Hits	340	Shared Neighborhood Hits	2
SwissProt Accessions	P58304	Gene names	CHX10, VSX2
Domain Architecture
Description	Homeobox protein CHX10 (Ceh-10 homeodomain-containing homolog).

ZSCA1_HUMAN
NC score	-0.000435 (rank : 138)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	105	Target Neighborhood Hits	724	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NBB4, Q6WLH8, Q86WS8	Gene names	ZSCAN1
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 1.

WNK2_HUMAN
NC score	-0.000673 (rank : 139)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	105	Target Neighborhood Hits	1407	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZBTB8_MOUSE
NC score	-0.001957 (rank : 140)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	105	Target Neighborhood Hits	791	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CII0	Gene names	Zbtb8
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 8.